Page last updated: 2024-08-21

d-alpha tocopherol and tocotrienol, alpha

d-alpha tocopherol has been researched along with tocotrienol, alpha in 100 studies

Research

Studies (100)

TimeframeStudies, this research(%)All Research%
pre-19902 (2.00)18.7374
1990's21 (21.00)18.2507
2000's39 (39.00)29.6817
2010's36 (36.00)24.3611
2020's2 (2.00)2.80

Authors

AuthorsStudies
Deason, ME; Parker, RA; Pearce, BC; Qureshi, AA; Wright, JJ1
Fukuhara, A; Kato, H; Niki, E; Nishio, K; Omata, Y; Saito, Y; Yamaguchi, S; Yoshida, Y1
Bamonti, L; Böhmdorfer, S; Galli, F; Gille, L; Kelly, FJ; Mazzini, F; Netscher, T; Piroddi, M; Rosenau, T1
Han, D; Kagan, V; Packer, L; Serbinova, E1
Heinonen, M; Piironen, V1
Weimann, BJ; Weiser, H1
Iizuka, K; Komiyama, K; Tsuchiya, N; Umezawa, I; Watanabe, H; Yamaoka, M1
Koivistoinen, P; Piironen, V; Salminen, K; Syväoja, EL; Varo, P1
Järvinen, R1
Komiyama, K; Yamaoka, M1
Packer, L; Serbinova, EA1
Khalid, BA; Ong, FB; Shamaan, NA; Top, AG; Wan Ngah, WZ1
Choo, YM; Govil, G; Kagan, VE; Packer, L; Suzuki, YJ; Tsuchiya, M; Wassall, SR1
Dean, RT; Hood, RL; Stocker, R; Suarna, C1
Hofer, PJ; Jackson, LL; Newman, CW; Newman, RK; Wang, L1
Devasagayam, TP; Kamat, JP2
Ikeda, I; Imasato, Y; Sasaki, E; Sugano, M1
Adam, A; Marzuki, A; Ngah, WZ; Top, GM1
Carroll, KK; Chambers, AF; Gapor, A; Guthrie, N1
Basiron, Y; Devasagayam, TP; Kamat, JP; Nesaretnam, K; Sarma, HD1
Maibach, HI; Packer, L; Podda, M; Rallis, M; Traber, MG; Weber, C1
Darbre, P; Dils, R; Nesaretnam, K; Stephen, R1
Speake, BK; Surai, PF1
Gapor, A; Kline, K; Sanders, BG; Simmons-Menchaca, M; Yu, W1
Addis, PB; Katsanidis, E1
Briski, KP; Fariss, MW; Gapor, A; McIntyre, BS; Sylvester, PW; Tirmenstein, MA1
Khanna, S; Packer, L; Roy, S; Sen, CK1
Adachi, H; Ishii, N1
Ikeda, S; Niwa, T; Yamashita, K1
Black, TM; Coleman, RA; Maeda, N; Wang, P1
Packer, L; Rimbach, G; Weber, SU1
Wong, JW; Yap, SP; Yuen, KH1
Leonard, S; Lodge, JK; Ridlington, J; Traber, MG; Vaule, H1
German, B; Kaushik, S; Leonard, S; Traber, MG; Wander, R1
Drotleff, AM; Ternes, W1
Furukawa, F; Hirose, M; Imazawa, T; Miyauchi, M; Nakamura, H; Nishikawa, A; Son, HY1
Ikeda, S; Toyoshima, K; Yamashita, K1
Briski, KP; Gapor, A; McIntyre, BS; Sylvester, PW1
Chao, JT; Gapor, A; Theriault, A1
Begum, AN; Terao, J1
Iizuka, Y; Ikeda, I; Ikeda, S; Yamashita, K1
DeMichele, SJ; Edens, NK; Mustad, VA; Ruey, PP; Smith, CA1
Han, N; Luu, C; Packer, L; Thiele, JJ; Valacchi, G; Weber, S; Weber, SU1
Egashira, N; Fujiwara, M; Hidaka, R; Iwasaki, K; Karube, Y; Matsunaga, K; Mishima, K; Pu, F; Takata, J; Tanaka, T1
Fuchs, J; Groth, N; Herrling, T; Kaufmann, R; Packer, L; Podda, M; Weber, S1
Abe, K; Hamamura, K; Ikeda, S; Tohyama, T; Yamashita, K; Yoshimura, H1
Lim, AB; Yap, SP; Yuen, KH1
Hanyu, R; Kodama, T; Noguchi, N; Nonaka, A; Okimoto, Y1
Bahadduri, P; Khanna, S; Ratan, RR; Roy, S; Ryu, H; Sen, CK; Swaan, PW1
Yap, SP; Yuen, KH1
Akaike, A; Hashino, A; Kaneko, S; Katsuki, H; Kume, T; Osakada, F1
Hayakawa, M; Niki, E; Nishio, K; Saito, Y; Yoshida, Y1
Chua, CW; Ima-Nirwana, S; Norazlina, M1
Chaki, S; Craft, TK; DeVries, AC; Khanna, S; Notestine, MA; Parinandi, NL; Rink, C; Roy, S; Sen, CK; Slivka, A1
Khanna, S; Patel, V; Rink, C; Roy, S; Sen, CK1
Okabe, M; Sakai, M; Tachibana, H; Yamada, K1
Chênevert, R; Courchesne, G; Pelchat, N1
Kumamaru, E; Kunugi, H; Matsumoto, T; Niki, E; Numakawa, T; Numakawa, Y; Taguchi, T; Yagasaki, Y1
Khanna, S; Maurer, M; Parinandi, NL; Roy, S; Sen, CK1
Gapor, A; Qureshi, AA; Qureshi, N; Tan, B; Thomas, AM; Yu, SG1
Abe, C; Ichikawa, T; Ikeda, S; Uchida, T; Yamashita, K1
Avanzi, L; Bravo, E; Manfredini, S; Napolitano, M1
Bibus, D; Khanna, S; Kotha, SR; Parinandi, NL; Rink, C; Roy, S; Sen, CK1
Gogvadze, V; Norberg, E; Orrenius, S; Zhivotovsky, B1
Kang, Z; Li, F; Tan, W; Wong, CW1
Galli, F; Pierpaoli, E; Pilolli, F; Piroddi, M; Provinciali, M; Viola, V1
Akazawa, YO; Miyama, A; Niki, E; Nishio, K; Noguchi, N; Saito, Y; Yamanaka, K; Yoshida, Y1
Ha, H; Kim, HN; Lee, JH; Lee, ZH1
Checker, R; Devasagayam, TP; Khan, NM; Patil, A; Patwardhan, R; Sandur, SK; Sharma, D; Wilankar, C1
Amagata, A; Barnes, A; Enns, GM; Hinman, A; Jankowski, O; Kheifets, V; Komatsuzaki, R; Lee, E; Miller, G; Mollard, P; Murase, K; Sadun, AA; Shrader, WD; Thoolen, M; Wesson, K1
Chan, YC; Gnyawali, S; Khanna, S; Kubicki, N; Park, HA; Roy, S; Sen, CK1
Abdullah, M; Ramasamy, R; Tan, SW; Vidyadaran, S1
Abe, C; Ichikawa, T; Ikeda, S; Nomura, S; Uchida, T2
Fukui, K; Koike, T; Takatsu, H; Urano, S; Ushiki, K1
Constantinou, AI; Constantinou, C; Hyatt, JA; Neophytou, CM; Papas, KA; Vraka, P1
Cheng, HM; Fairus, S; Nor, RM; Sundram, K1
Cheong, SK; Ibrahim, TA; Radhakrishnan, AK; Wong, RS1
Brown, AJ; Krycer, JR; Phan, L1
Li, Y; Liang, GH; Liu, QQ; Liu, RR; Tang, KX; Xu, G; Zhang, GY; Zhang, P1
Baglioni, M; Cecchetti, R; Floridi, P; Gobbi, G; Kivipelto, M; Kłoszewska, I; Lovestone, S; Mangialasche, F; Mecocci, P; Muehlboeck, JS; Simmons, A; Soininen, H; Spenger, C; Tarducci, R; Tsolaki, M; Vellas, B; Wahlund, LO; Westman, E1
Loganathan, R; Nesaretnam, K; Radhakrishnan, AK; Selvaduray, KR1
Birringer, M; Ciobanu, I; Eckert, GP; Eckert, SH; El-Askary, H; Frank, J; Hagl, S; Helal, A; Khayyal, MT; Kocher, A; Muller, WE; Schiborr, C1
Cela, J; Munné-Bosch, S; Siles, L1
Jung, NY; Lee, BH; Lee, KH; Won, R1
Ghazali, HM; Muhammad, K; Ramakrishnan, Y; Shammugasamy, B1
Gerling, EM; Ternes, W1
Ishikawa, E; Izumisawa, K; Koike, T; Mukai, K; Nagaoka, S; Ouchi, A; Suzuki, T1
Bradshaw, TD; Lim, SW; Loh, HS; Ting, KN; Zeenathul, NA1
Bicalho, EM; Garcia, QS; Morales, M; Müller, M; Munné-Bosch, S; Pintó-Marijuan, M1
Able, AJ; Box, A; Cozzolino, D; Do, TD; Muhlhausler, B1
Brown, L; Fong, CW; Ward, LC; Wong, WY; Yap, WN1
Gay, MC; Gee, PT; Liew, CY; Thong, MC1
Miyanoki, Y; Nakazawa, T; Noguchi, N; Saito, Y; Uehara, M; Urano, Y1
Chia, LL; Chua, KH; Jantan, I1
Kushairi, A; Ng, MH1
Caccia, C; Cherkaoui-Malki, M; Leoni, V; Lizard, G; Meddeb, W; Ménétrier, F; Mihoubi, W; Moreau, T; Namsi, A; Nury, T; Riedinger, JM; Sassi, K; Sghaier, R; Uzun, T; Vejux, A; Zarrouk, A1
Nakatani, Y; Noguchi, N; Shimokawa, N; Takagi, M; Urano, Y1
Hido, M; Ishii, K; Sakamura, M; Virgona, N; Yano, T1

Reviews

1 review(s) available for d-alpha tocopherol and tocotrienol, alpha

ArticleYear
Molecular aspects of alpha-tocotrienol antioxidant action and cell signalling.
    The Journal of nutrition, 2001, Volume: 131, Issue:2

    Topics: Animals; Anticarcinogenic Agents; Anticholesteremic Agents; Antioxidants; Biological Availability; Cholesterol; Humans; Hydroxymethylglutaryl CoA Reductases; Intestinal Absorption; Lipoproteins, LDL; Oxidation-Reduction; Oxidative Stress; Protein Isoforms; Signal Transduction; Tissue Distribution; Tocotrienols; Vitamin E

2001

Trials

4 trial(s) available for d-alpha tocopherol and tocotrienol, alpha

ArticleYear
Pharmacokinetics and bioavailability of alpha-, gamma- and delta-tocotrienols under different food status.
    The Journal of pharmacy and pharmacology, 2001, Volume: 53, Issue:1

    Topics: Administration, Oral; Adult; Antioxidants; Area Under Curve; Biological Availability; Chromans; Eating; Fasting; Half-Life; Humans; Male; Middle Aged; Tocotrienols; Vitamin E

2001
Alpha- and gamma-tocotrienols are metabolized to carboxyethyl-hydroxychroman derivatives and excreted in human urine.
    Lipids, 2001, Volume: 36, Issue:1

    Topics: Chromans; Chromatography, High Pressure Liquid; Dietary Supplements; Female; Humans; Kinetics; Male; Propionates; Tocotrienols; Vitamin E

2001
Supplementation with 3 compositionally different tocotrienol supplements does not improve cardiovascular disease risk factors in men and women with hypercholesterolemia.
    The American journal of clinical nutrition, 2002, Volume: 76, Issue:6

    Topics: Adult; Aged; Cardiovascular Diseases; Cholesterol; Cholesterol, LDL; Chromans; Dietary Supplements; Dinoprost; Double-Blind Method; F2-Isoprostanes; Female; Humans; Hypercholesterolemia; Male; Middle Aged; Placebos; Risk Factors; Tocopherols; Tocotrienols; Vitamin E

2002
Topical alpha-tocotrienol supplementation inhibits lipid peroxidation but fails to mitigate increased transepidermal water loss after benzoyl peroxide treatment of human skin.
    Free radical biology & medicine, 2003, Jan-15, Volume: 34, Issue:2

    Topics: Administration, Topical; Adult; Benzoyl Peroxide; Chromatography, High Pressure Liquid; Double-Blind Method; Female; Humans; Lipid Peroxidation; Male; Skin; Tocotrienols; Vitamin E; Water Loss, Insensible

2003

Other Studies

95 other study(ies) available for d-alpha tocopherol and tocotrienol, alpha

ArticleYear
Hypocholesterolemic activity of synthetic and natural tocotrienols.
    Journal of medicinal chemistry, 1992, Oct-02, Volume: 35, Issue:20

    Topics: Animals; Anticholesteremic Agents; Cells, Cultured; Chickens; Cholesterol; Chromans; Humans; Hydroxymethylglutaryl CoA Reductases; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Liver; Male; Rats; Rats, Wistar; Tocotrienols; Vitamin E

1992
Characterization of novel furan compounds on the basis of their radical scavenging activity and cytoprotective effects against glutamate- and lipopolysaccharide-induced insults.
    Bioorganic & medicinal chemistry, 2008, Dec-15, Volume: 16, Issue:24

    Topics: Animals; Antioxidants; beta Carotene; Cell Death; Cells, Cultured; Cyclooxygenase Inhibitors; Cytoprotection; Free Radical Scavengers; Furans; Glutamates; Inhibitory Concentration 50; Lipopolysaccharides; Rats; Rats, Sprague-Dawley; Vitamins

2008
Tocotrienamines and tocopheramines: reactions with radicals and metal ions.
    Bioorganic & medicinal chemistry, 2011, Nov-01, Volume: 19, Issue:21

    Topics: Amines; Biphenyl Compounds; Chromans; Electron Spin Resonance Spectroscopy; Ferric Compounds; Free Radical Scavengers; Kinetics; Magnetic Resonance Spectroscopy; Oxidation-Reduction; Picrates; Vitamin E

2011
Free radical recycling and intramembrane mobility in the antioxidant properties of alpha-tocopherol and alpha-tocotrienol.
    Free radical biology & medicine, 1991, Volume: 10, Issue:5

    Topics: Animals; Antioxidants; Chromans; Cytochrome P-450 Enzyme System; Electron Spin Resonance Spectroscopy; Female; Free Radicals; Lipid Bilayers; Lipid Peroxidation; Liposomes; Magnetic Resonance Spectroscopy; Membrane Fluidity; Membrane Lipids; Microsomes, Liver; Rats; Rats, Inbred Strains; Spectrometry, Fluorescence; Tocotrienols; Vitamin E

1991
The tocopherol, tocotrienol, and vitamin E content of the average Finnish diet.
    International journal for vitamin and nutrition research. Internationale Zeitschrift fur Vitamin- und Ernahrungsforschung. Journal international de vitaminologie et de nutrition, 1991, Volume: 61, Issue:1

    Topics: Antioxidants; Chromans; Diet; Eating; Fatty Acids, Unsaturated; Finland; Food Analysis; Humans; Seasons; Tocotrienols; Vitamin E

1991
Functions of vitamin E in reproduction and in prostacyclin and immunoglobulin synthesis in rats.
    The American journal of clinical nutrition, 1991, Volume: 53, Issue:4 Suppl

    Topics: Animals; Epoprostenol; Female; Immunoglobulin G; Palm Oil; Plant Oils; Pregnancy; Pregnancy, Animal; Pyruvate Kinase; Rats; Tocotrienols; Vitamin E

1991
Studies on the biological activity of tocotrienols.
    Chemical & pharmaceutical bulletin, 1989, Volume: 37, Issue:5

    Topics: Animals; Antineoplastic Agents; Chromans; Female; Lipid Peroxidation; Mice; Mice, Inbred BALB C; Mice, Inbred ICR; Tocotrienols; Vitamin E

1989
High-performance liquid chromatographic determination of tocopherols and tocotrienols and its application to diets and plasma of Finnish men. I. Analytical method.
    International journal for vitamin and nutrition research. Internationale Zeitschrift fur Vitamin- und Ernahrungsforschung. Journal international de vitaminologie et de nutrition, 1984, Volume: 54, Issue:1

    Topics: Butylated Hydroxyanisole; Chromans; Chromatography, High Pressure Liquid; Food, Formulated; Hexanes; Humans; Hydroxides; Male; Potassium; Potassium Compounds; Solvents; Tocotrienols; Vitamin E

1984
Carotenoids, retinoids, tocopherols and tocotrienols in the diet; the Finnish Mobile Clinic Health Examination Survey.
    International journal for vitamin and nutrition research. Internationale Zeitschrift fur Vitamin- und Ernahrungsforschung. Journal international de vitaminologie et de nutrition, 1995, Volume: 65, Issue:1

    Topics: Adult; Antioxidants; Carotenoids; Chromatography, High Pressure Liquid; Diet; Female; Finland; Food Analysis; Health Surveys; Humans; Male; Middle Aged; Mobile Health Units; Nutrition Surveys; Retinoids; Tocotrienols; Vitamin E

1995
Antioxidative activity of tocotrienol in heterogeneous system: indication of restriction within membrane by fluorescence measurement.
    Methods in enzymology, 1994, Volume: 234

    Topics: Antioxidants; Diphenylhexatriene; Dose-Response Relationship, Drug; Liposomes; Phospholipids; Spectrometry, Fluorescence; Structure-Activity Relationship; Tocotrienols; Vitamin E

1994
Antioxidant properties of alpha-tocopherol and alpha-tocotrienol.
    Methods in enzymology, 1994, Volume: 234

    Topics: Animals; Antioxidants; Ascorbic Acid; Electron Spin Resonance Spectroscopy; Erythrocyte Membrane; Free Radical Scavengers; Free Radicals; Hexanes; Humans; Indicators and Reagents; Iron; Kinetics; Lipid Peroxidation; Liposomes; Microsomes; Mitochondria, Heart; Myocardium; Rats; Superoxides; Tocotrienols; Vitamin E

1994
Vitamin E, glutathione S-transferase and gamma-glutamyl transpeptidase activities in cultured hepatocytes of rats treated with carcinogens.
    The International journal of biochemistry, 1994, Volume: 26, Issue:3

    Topics: 2-Acetylaminofluorene; Animals; Carcinogens; Cells, Cultured; Diethylnitrosamine; Drug Interactions; gamma-Glutamyltransferase; Glutathione Transferase; Liver; Male; Rats; Thymidine; Tocotrienols; Vitamin E

1994
Structural and dynamic membrane properties of alpha-tocopherol and alpha-tocotrienol: implication to the molecular mechanism of their antioxidant potency.
    Biochemistry, 1993, Oct-12, Volume: 32, Issue:40

    Topics: Antioxidants; Electron Spin Resonance Spectroscopy; Free Radical Scavengers; Free Radicals; Lipid Peroxidation; Magnetic Resonance Spectroscopy; Membranes; Models, Biological; Oxygen Consumption; Peroxides; Spectrometry, Fluorescence; Thermodynamics; Tocotrienols; Vitamin E

1993
Comparative antioxidant activity of tocotrienols and other natural lipid-soluble antioxidants in a homogeneous system, and in rat and human lipoproteins.
    Biochimica et biophysica acta, 1993, Feb-24, Volume: 1166, Issue:2-3

    Topics: Adult; Animals; Antioxidants; Chromans; Dietary Fats, Unsaturated; Humans; Lipid Peroxidation; Lipids; Lipoproteins, LDL; Male; Oxidation-Reduction; Palm Oil; Plant Oils; Rats; Tocotrienols; Vitamin E

1993
Tocotrienol and fatty acid composition of barley oil and their effects on lipid metabolism.
    Plant foods for human nutrition (Dordrecht, Netherlands), 1993, Volume: 43, Issue:1

    Topics: Animal Feed; Animals; Antioxidants; Chickens; Cholesterol, HDL; Cholesterol, LDL; Chromans; Corn Oil; Diet; Dietary Fats, Unsaturated; Fatty Acids; Hordeum; Lipid Metabolism; Male; Margarine; Plant Oils; Tocotrienols; Triglycerides; Vitamin E; Weight Gain

1993
Tocotrienols from palm oil as potent inhibitors of lipid peroxidation and protein oxidation in rat brain mitochondria.
    Neuroscience letters, 1995, Aug-11, Volume: 195, Issue:3

    Topics: Animals; Antioxidants; Brain; Dietary Fats, Unsaturated; Female; Lipid Peroxidation; Mitochondria; Oxidation-Reduction; Palm Oil; Plant Oils; Proteins; Rats; Rats, Wistar; Tocotrienols; Vitamin E

1995
Lymphatic transport of alpha-, gamma- and delta-tocotrienols and alpha-tocopherol in rats.
    International journal for vitamin and nutrition research. Internationale Zeitschrift fur Vitamin- und Ernahrungsforschung. Journal international de vitaminologie et de nutrition, 1996, Volume: 66, Issue:3

    Topics: Animals; Biological Transport; Chromans; Emulsions; Intestinal Absorption; Kinetics; Lymphatic System; Male; Oleic Acid; Rats; Rats, Sprague-Dawley; Thoracic Duct; Tocotrienols; Triolein; Vitamin E

1996
Nitrofurantoin-induced hepatic and pulmonary biochemical changes in mice fed different vitamin E doses.
    Pharmacology & toxicology, 1996, Volume: 79, Issue:6

    Topics: Animals; Antioxidants; Catalase; Drug Interactions; Glutathione; Glutathione Peroxidase; Liver; Lung; Male; Malondialdehyde; Mice; Nitrofurantoin; Tocotrienols; Vitamin E; Vitamin E Deficiency

1996
Inhibition of proliferation of estrogen receptor-negative MDA-MB-435 and -positive MCF-7 human breast cancer cells by palm oil tocotrienols and tamoxifen, alone and in combination.
    The Journal of nutrition, 1997, Volume: 127, Issue:3

    Topics: Antineoplastic Agents, Hormonal; Antioxidants; Breast Neoplasms; Cell Division; Cell Survival; Chromans; Dietary Fats, Unsaturated; Drug Interactions; Estrogen Antagonists; Female; Humans; Palm Oil; Plant Oils; Receptors, Estrogen; Tamoxifen; Tocotrienols; Tumor Cells, Cultured; Vitamin E

1997
Tocotrienols from palm oil as effective inhibitors of protein oxidation and lipid peroxidation in rat liver microsomes.
    Molecular and cellular biochemistry, 1997, Volume: 170, Issue:1-2

    Topics: Animals; Antioxidants; Chromans; Female; Kinetics; Lipid Peroxidation; Microsomes, Liver; Oxidation-Reduction; Palm Oil; Plant Oils; Proteins; Rats; Rats, Wistar; Thiobarbituric Acid Reactive Substances; Tocotrienols; Vitamin E

1997
Penetration and distribution of alpha-tocopherol, alpha- or gamma-tocotrienols applied individually onto murine skin.
    Lipids, 1998, Volume: 33, Issue:1

    Topics: Administration, Topical; Animals; Chromans; Female; Kinetics; Mice; Mice, Hairless; Polyethylene Glycols; Skin; Solutions; Tissue Distribution; Tocotrienols; Vitamin E

1998
Tocotrienols inhibit the growth of human breast cancer cells irrespective of estrogen receptor status.
    Lipids, 1998, Volume: 33, Issue:5

    Topics: Breast Neoplasms; Cell Division; Estradiol; Female; Humans; Insulin-Like Growth Factor Binding Proteins; Receptors, Estrogen; Tocotrienols; Tumor Cells, Cultured; Vitamin E

1998
Selective excretion of yolk-derived tocotrienols into the bile of the chick embryo.
    Comparative biochemistry and physiology. Part B, Biochemistry & molecular biology, 1998, Volume: 121, Issue:4

    Topics: Animals; Animals, Newborn; Bile; Chick Embryo; Chickens; Chromans; Liver; Tissue Distribution; Tocotrienols; Vitamin E; Yolk Sac

1998
Induction of apoptosis in human breast cancer cells by tocopherols and tocotrienols.
    Nutrition and cancer, 1999, Volume: 33, Issue:1

    Topics: Antioxidants; Apoptosis; Breast Neoplasms; Chromans; Chromatin; DNA, Neoplasm; Female; Humans; Neoplasms, Hormone-Dependent; Tocotrienols; Tumor Cells, Cultured; Vitamin E

1999
Novel HPLC analysis of tocopherols, tocotrienols, and cholesterol in tissue.
    Free radical biology & medicine, 1999, Volume: 27, Issue:11-12

    Topics: Animals; Antioxidants; Cattle; Cholesterol; Chromans; Chromatography, High Pressure Liquid; Muscles; Saponins; Sensitivity and Specificity; Tocotrienols; Vitamin E

1999
Antiproliferative and apoptotic effects of tocopherols and tocotrienols on normal mouse mammary epithelial cells.
    Lipids, 2000, Volume: 35, Issue:2

    Topics: Animals; Apoptosis; Cell Division; Cells, Cultured; Chromans; DNA Fragmentation; Dose-Response Relationship, Drug; Epidermal Growth Factor; Epithelial Cells; Female; Inhibitory Concentration 50; Isomerism; Mammary Glands, Animal; Mice; Mice, Inbred BALB C; Palm Oil; Plant Oils; Tocotrienols; Vitamin E

2000
Molecular basis of vitamin E action. Tocotrienol potently inhibits glutamate-induced pp60(c-Src) kinase activation and death of HT4 neuronal cells.
    The Journal of biological chemistry, 2000, Apr-28, Volume: 275, Issue:17

    Topics: Animals; Benzoquinones; Cell Death; Cells, Cultured; Chelating Agents; Chromans; Chromatography, High Pressure Liquid; Deferoxamine; Enzyme Activation; Enzyme Inhibitors; Flow Cytometry; Glutamic Acid; Hippocampus; Immunoblotting; Lactams, Macrocyclic; Mice; Neurons; Phosphotyrosine; Proto-Oncogene Proteins pp60(c-src); Quinones; Rats; Signal Transduction; Time Factors; Tocotrienols; Transfection; Vitamin E

2000
Effects of tocotrienols on life span and protein carbonylation in Caenorhabditis elegans.
    The journals of gerontology. Series A, Biological sciences and medical sciences, 2000, Volume: 55, Issue:6

    Topics: Animals; Antioxidants; Caenorhabditis elegans; Chromans; Longevity; Proteins; Tocotrienols; Vitamin E

2000
Selective uptake of dietary tocotrienols into rat skin.
    Journal of nutritional science and vitaminology, 2000, Volume: 46, Issue:3

    Topics: Animals; Antioxidants; Chromans; Diet; Female; Kidney; Liver; Male; Mice; Mice, Hairless; Mice, Inbred BALB C; Mice, Nude; Rats; Rats, Wistar; Skin; Tissue Distribution; Tocotrienols; Vitamin E

2000
Palm tocotrienols protect ApoE +/- mice from diet-induced atheroma formation.
    The Journal of nutrition, 2000, Volume: 130, Issue:10

    Topics: Animals; Apolipoproteins E; Arteriosclerosis; Cholesterol; Cholesterol, Dietary; Chromans; Chromatography, High Pressure Liquid; Dietary Fats; Female; Lipid Metabolism; Lipoproteins; Liver; Male; Mice; Mice, Inbred C57BL; Tocotrienols; Triglycerides; Vitamin E

2000
Oxidative damage to mitochondria in normal and cancer tissues, and its modulation.
    Toxicology, 2000, Nov-30, Volume: 155, Issue:1-3

    Topics: Animals; Antioxidants; Ascites; Brain; Caffeine; Gamma Rays; Male; Mitochondria, Liver; Niacinamide; Oxidative Stress; Palm Oil; Photosensitizing Agents; Plant Oils; Porphyrins; Pulse Radiolysis; Rats; Rats, Wistar; Sarcoma 180; Tocotrienols; Vitamin E

2000
Removal of fat from cow's milk decreases the vitamin E contents of the resulting dairy products.
    Lipids, 2001, Volume: 36, Issue:1

    Topics: Animals; Cholesterol; Dairy Products; Food Handling; Lipids; Milk; Tocotrienols; Vitamin E

2001
Determination of RS,E/Z-tocotrienols by HPLC.
    Journal of chromatography. A, 2001, Feb-16, Volume: 909, Issue:2

    Topics: Chromatography, High Pressure Liquid; Sensitivity and Specificity; Stereoisomerism; Tocotrienols; Vitamin E

2001
Oral toxicity of a tocotrienol preparation in rats.
    Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association, 2001, Volume: 39, Issue:8

    Topics: Administration, Oral; Adrenal Glands; Animals; Blood Cell Count; Chromans; Dose-Response Relationship, Drug; Female; Food Additives; Genitalia; Kidney; Liver; Male; No-Observed-Adverse-Effect Level; Rats; Rats, Inbred F344; Sex Factors; Tocotrienols; Vitamin E

2001
Dietary sesame seeds elevate alpha- and gamma-tocotrienol concentrations in skin and adipose tissue of rats fed the tocotrienol-rich fraction extracted from palm oil.
    The Journal of nutrition, 2001, Volume: 131, Issue:11

    Topics: Adipose Tissue; Analysis of Variance; Animals; Body Weight; Chromans; Diet; Male; Organ Size; Palm Oil; Plant Oils; Rats; Rats, Wistar; Seeds; Skin; Tissue Distribution; Tocotrienols; Vitamin E

2001
Vitamin E inhibition of normal mammary epithelial cell growth is associated with a reduction in protein kinase C(alpha) activation.
    Cell proliferation, 2001, Volume: 34, Issue:6

    Topics: alpha-Tocopherol; Animals; Blotting, Western; Cell Division; Cells, Cultured; Chromans; Dose-Response Relationship, Drug; Electrophoresis, Polyacrylamide Gel; Enzyme Activation; Epidermal Growth Factor; Epithelial Cells; Female; gamma-Tocopherol; Mice; Mice, Inbred BALB C; Pregnancy; Protein Kinase C; Time Factors; Tocotrienols; Vitamin E

2001
Tocotrienol is the most effective vitamin E for reducing endothelial expression of adhesion molecules and adhesion to monocytes.
    Atherosclerosis, 2002, Volume: 160, Issue:1

    Topics: Antioxidants; Cell Survival; Dose-Response Relationship, Drug; E-Selectin; Endothelium, Vascular; Humans; Intercellular Adhesion Molecule-1; Interleukin-1; Monocytes; NF-kappa B; Protein Prenylation; Tetradecanoylphorbol Acetate; Tocotrienols; Tumor Necrosis Factor-alpha; Vitamin E

2002
Protective effect of alpha-tocotrienol against free radical-induced impairment of erythrocyte deformability.
    Bioscience, biotechnology, and biochemistry, 2002, Volume: 66, Issue:2

    Topics: Erythrocyte Deformability; Free Radicals; Hemolysis; Humans; Lipid Peroxidation; Oxidation-Reduction; Tocotrienols; Vitamin E

2002
Effect of sesaminol on plasma and tissue alpha-tocopherol and alpha-tocotrienol concentrations in rats fed a vitamin E concentrate rich in tocotrienols.
    Lipids, 2002, Volume: 37, Issue:4

    Topics: alpha-Tocopherol; Animals; Dioxoles; Furans; Male; Rats; Rats, Wistar; Tissue Distribution; Tocotrienols; Vitamin E

2002
Vitamin E isoforms alpha-tocotrienol and gamma-tocopherol prevent cerebral infarction in mice.
    Neuroscience letters, 2003, Jan-30, Volume: 337, Issue:1

    Topics: Animals; gamma-Tocopherol; Infarction, Middle Cerebral Artery; Male; Mice; Structure-Activity Relationship; Tocotrienols; Vitamin E

2003
HPLC analysis of vitamin E isoforms in human epidermis: correlation with minimal erythema dose and free radical scavenging activity.
    Free radical biology & medicine, 2003, Feb-01, Volume: 34, Issue:3

    Topics: alpha-Tocopherol; Chromans; Chromatography, High Pressure Liquid; Electron Spin Resonance Spectroscopy; Epidermis; Erythema; Free Radical Scavengers; Free Radicals; gamma-Tocopherol; Humans; Isomerism; Microbial Sensitivity Tests; Tocotrienols; Vitamin E

2003
Dietary alpha-tocopherol decreases alpha-tocotrienol but not gamma-tocotrienol concentration in rats.
    The Journal of nutrition, 2003, Volume: 133, Issue:2

    Topics: Adipose Tissue; alpha-Tocopherol; Animals; Antioxidants; Body Weight; Chromans; Diet; Male; Pyruvate Kinase; Rats; Rats, Wistar; Tissue Distribution; Tocotrienols; Vitamin E

2003
Influence of route of administration on the absorption and disposition of alpha-, gamma- and delta-tocotrienols in rats.
    The Journal of pharmacy and pharmacology, 2003, Volume: 55, Issue:1

    Topics: Administration, Oral; Animals; Biological Availability; Chromans; Cross-Over Studies; Infusions, Intravenous; Infusions, Parenteral; Injections, Intramuscular; Male; Rats; Rats, Sprague-Dawley; Tissue Distribution; Tocotrienols; Vitamin E

2003
Inhibition of THP-1 cell adhesion to endothelial cells by alpha-tocopherol and alpha-tocotrienol is dependent on intracellular concentration of the antioxidants.
    Free radical biology & medicine, 2003, Jun-15, Volume: 34, Issue:12

    Topics: alpha-Tocopherol; Antioxidants; Cell Adhesion; Cell Survival; Cells, Cultured; Dose-Response Relationship, Drug; Endothelium, Vascular; Free Radical Scavengers; Humans; Lipid Peroxidation; Monocytes; Tocotrienols; Vascular Cell Adhesion Molecule-1; Vitamin E

2003
Molecular basis of vitamin E action: tocotrienol modulates 12-lipoxygenase, a key mediator of glutamate-induced neurodegeneration.
    The Journal of biological chemistry, 2003, Oct-31, Volume: 278, Issue:44

    Topics: Animals; Arachidonate 12-Lipoxygenase; Binding Sites; Cell Death; Cell Survival; Cells, Cultured; Cytosol; Glutamic Acid; Glutathione; Hippocampus; Mice; Mice, Inbred C57BL; Microscopy, Fluorescence; Models, Molecular; Neurodegenerative Diseases; Neurons; Neurotoxins; Protein Structure, Secondary; Protein Structure, Tertiary; Rats; Rats, Sprague-Dawley; Time Factors; Tocotrienols; Vitamin E

2003
Influence of lipolysis and droplet size on tocotrienol absorption from self-emulsifying formulations.
    International journal of pharmaceutics, 2004, Aug-20, Volume: 281, Issue:1-2

    Topics: Administration, Oral; Adult; Area Under Curve; Biological Availability; Chemistry, Pharmaceutical; Chromans; Chromatography, High Pressure Liquid; Cross-Over Studies; Emulsions; Glycerides; Half-Life; Humans; Lipolysis; Male; Organic Chemicals; Particle Size; Polysorbates; Soybean Oil; Tocotrienols; Vitamin E

2004
Alpha-tocotrienol provides the most potent neuroprotection among vitamin E analogs on cultured striatal neurons.
    Neuropharmacology, 2004, Volume: 47, Issue:6

    Topics: Animals; Antimetabolites; Antioxidants; Apoptosis; Bisbenzimidazole; Buthionine Sulfoximine; Carcinogens; Cell Survival; Cells, Cultured; Chromatography, High Pressure Liquid; Fluorescent Dyes; Hydrogen Peroxide; Immunohistochemistry; In Situ Nick-End Labeling; L-Lactate Dehydrogenase; Neostriatum; Neurons; Neuroprotective Agents; Oxidative Stress; Rats; Rats, Wistar; Staurosporine; Tetrazolium Salts; Thiazoles; Tocotrienols; Vitamin E

2004
Characterization of cellular uptake and distribution of vitamin E.
    Annals of the New York Academy of Sciences, 2004, Volume: 1031

    Topics: alpha-Tocopherol; Antioxidants; Cell Fractionation; Cell Survival; Humans; Jurkat Cells; Oxidative Stress; Subcellular Fractions; Tocotrienols; Vitamin E

2004
Vitamin E deficiency reduced lumbar bone calcium content in female rats.
    The Medical journal of Malaysia, 2004, Volume: 59, Issue:5

    Topics: alpha-Tocopherol; Amino Acids; Animals; Antioxidants; Calcium; Creatinine; Dietary Supplements; Female; Lumbar Vertebrae; Osteocalcin; Parathyroid Hormone; Rats; Rats, Sprague-Dawley; Tocotrienols; Vitamin E; Vitamin E Deficiency

2004
Neuroprotective properties of the natural vitamin E alpha-tocotrienol.
    Stroke, 2005, Volume: 36, Issue:10

    Topics: Animals; Antioxidants; Arachidonate 12-Lipoxygenase; Brain; Cell Death; Cell Line; Cell Survival; Cells, Cultured; Cerebral Cortex; CSK Tyrosine-Protein Kinase; Fluoresceins; Glutamic Acid; Hippocampus; Immunohistochemistry; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; Neurons; Neuroprotective Agents; Organic Chemicals; Phosphorylation; Protein-Tyrosine Kinases; Proto-Oncogene Proteins pp60(c-src); Random Allocation; Rats; Rats, Inbred SHR; src-Family Kinases; Stroke; Time Factors; Tocotrienols; Transfection; Tyrosine; Vitamin E

2005
Delivery of orally supplemented alpha-tocotrienol to vital organs of rats and tocopherol-transport protein deficient mice.
    Free radical biology & medicine, 2005, Nov-15, Volume: 39, Issue:10

    Topics: Administration, Oral; Animals; Antioxidants; Biological Transport; Carrier Proteins; Female; Humans; Lung; Male; Mice; Mice, Knockout; Mice, Transgenic; Muscle, Skeletal; Neuroprotective Agents; Rats; Rats, Sprague-Dawley; Time Factors; Tissue Distribution; Tocopherols; Tocotrienols; Vitamin E

2005
Apoptosis induction by gamma-tocotrienol in human hepatoma Hep3B cells.
    The Journal of nutritional biochemistry, 2006, Volume: 17, Issue:10

    Topics: Apoptosis; Carcinoma, Hepatocellular; Caspase 3; Caspase 8; Caspase 9; Caspases; Cell Division; Cell Line, Tumor; Chromans; Gene Expression; Genes, bcl-2; Humans; Liver Neoplasms; Poly(ADP-ribose) Polymerases; Tocotrienols; Vitamin E

2006
Chemoenzymatic synthesis of both enantiomers of alpha-tocotrienol.
    Bioorganic & medicinal chemistry, 2006, Aug-01, Volume: 14, Issue:15

    Topics: Acylation; Candida; Esters; Fungal Proteins; Hydrolysis; Lipase; Molecular Structure; Stereoisomerism; Tocotrienols; Vitamin E

2006
Vitamin E protected cultured cortical neurons from oxidative stress-induced cell death through the activation of mitogen-activated protein kinase and phosphatidylinositol 3-kinase.
    Journal of neurochemistry, 2006, Volume: 97, Issue:4

    Topics: alpha-Tocopherol; Animals; Animals, Newborn; Cell Death; Cell Survival; Cells, Cultured; Cerebral Cortex; Chromans; Cytoprotection; Enzyme Inhibitors; MAP Kinase Signaling System; Mitogen-Activated Protein Kinase 1; Neurons; Neuroprotective Agents; Oxidative Stress; Phosphatidylinositol 3-Kinases; Proto-Oncogene Proteins c-bcl-2; Rats; Tocotrienols; Up-Regulation; Vitamin E

2006
Characterization of the potent neuroprotective properties of the natural vitamin E alpha-tocotrienol.
    Journal of neurochemistry, 2006, Volume: 98, Issue:5

    Topics: Animals; Arachidonate 12-Lipoxygenase; Calcium; Cell Survival; Cells, Cultured; Dose-Response Relationship, Drug; Drug Interactions; Embryo, Mammalian; Enzyme Inhibitors; Glutathione; Hippocampus; Homocysteine; Hydro-Lyases; Linoleic Acid; Membrane Potentials; Mice; Mitochondria; Neurons; Neuroprotective Agents; Neurotoxins; Rats; Rats, Sprague-Dawley; Reactive Oxygen Species; RNA, Small Interfering; Time Factors; Tocotrienols; Vitamin E

2006
Dose-response impact of various tocotrienols on serum lipid parameters in 5-week-old female chickens.
    Lipids, 2006, Volume: 41, Issue:5

    Topics: alpha-Tocopherol; Analysis of Variance; Animals; Chickens; Cholesterol; Cholesterol, HDL; Cholesterol, LDL; Dose-Response Relationship, Drug; Female; Hypercholesterolemia; Lipid Metabolism; Lipids; Palm Oil; Plant Oils; Tocotrienols; Vitamin E

2006
Triton WR1339, an inhibitor of lipoprotein lipase, decreases vitamin E concentration in some tissues of rats by inhibiting its transport to liver.
    The Journal of nutrition, 2007, Volume: 137, Issue:2

    Topics: alpha-Tocopherol; Animals; Biological Transport; Chromans; gamma-Tocopherol; Lipoprotein Lipase; Liver; Male; Polyethylene Glycols; Rats; Rats, Wistar; Tocotrienols; Triglycerides; Vitamin E

2007
Effects of new combinative antioxidant FeAOX-6 and alpha-tocotrienol on macrophage atherogenesis-related functions.
    Vascular pharmacology, 2007, Volume: 46, Issue:6

    Topics: Antioxidants; Arachidonic Acid; Atherosclerosis; Cells, Cultured; Cholesterol; Cholesterol Esters; Chromans; Cytokines; Dinoprost; Dinoprostone; Dose-Response Relationship, Drug; Foam Cells; Free Radicals; Humans; Inflammation; Macrophages; Receptors, Scavenger; Tocotrienols; Vitamin E

2007
Nanomolar vitamin E alpha-tocotrienol inhibits glutamate-induced activation of phospholipase A2 and causes neuroprotection.
    Journal of neurochemistry, 2010, Volume: 112, Issue:5

    Topics: Animals; Arachidonic Acid; Arachidonic Acids; Calcium; Cell Death; Cell Line, Transformed; Cell Size; Chelating Agents; Dose-Response Relationship, Drug; Down-Regulation; Drug Interactions; Egtazic Acid; Enzyme Activation; Enzyme Inhibitors; Fatty Acids; Glutamic Acid; Hippocampus; Mice; Neurons; Neuroprotective Agents; Phospholipase A2 Inhibitors; Phospholipases A2; RNA, Small Interfering; Subcellular Fractions; Tocotrienols; Transfection; Vitamin E

2010
Involvement of Ca2+ and ROS in alpha-tocopheryl succinate-induced mitochondrial permeabilization.
    International journal of cancer, 2010, Oct-15, Volume: 127, Issue:8

    Topics: alpha-Tocopherol; Animals; Antioxidants; Calcium; Caspase 3; Cell Membrane Permeability; Cells, Cultured; Cytochromes c; Humans; Hydrogen Peroxide; Jurkat Cells; Male; Mitochondria, Liver; Mitochondrial Membrane Transport Proteins; Mitochondrial Permeability Transition Pore; Neuroblastoma; Oxidants; Permeability; Rats; Rats, Sprague-Dawley; Reactive Oxygen Species; Tocotrienols; Vitamin E

2010
Tocotrienol enriched palm oil prevents atherosclerosis through modulating the activities of peroxisome proliferators-activated receptors.
    Atherosclerosis, 2010, Volume: 211, Issue:1

    Topics: Animals; Apolipoproteins E; Atherosclerosis; Chromans; Humans; Liver X Receptors; Male; Mice; Orphan Nuclear Receptors; Palm Oil; Peroxisome Proliferator-Activated Receptors; Plant Oils; PPAR alpha; Tocotrienols; Tumor Cells, Cultured; Vitamin E

2010
Gamma- and delta-tocotrienols exert a more potent anticancer effect than alpha-tocopheryl succinate on breast cancer cell lines irrespective of HER-2/neu expression.
    Life sciences, 2010, Apr-24, Volume: 86, Issue:17-18

    Topics: alpha-Tocopherol; Animals; Antineoplastic Agents; Apoptosis; Blotting, Western; Breast Neoplasms; Cell Line, Tumor; Cell Survival; Chromans; Drug Screening Assays, Antitumor; Female; Gene Expression Regulation, Neoplastic; Humans; Inhibitory Concentration 50; Mice; Receptor, ErbB-2; Tocotrienols; Vitamin E

2010
Cytoprotective effects of vitamin E homologues against glutamate-induced cell death in immature primary cortical neuron cultures: Tocopherols and tocotrienols exert similar effects by antioxidant function.
    Free radical biology & medicine, 2010, Nov-30, Volume: 49, Issue:10

    Topics: alpha-Tocopherol; Animals; Antioxidants; Cell Death; Cerebral Cortex; Glutamic Acid; Glutathione; Neurons; Rats; Tocopherols; Tocotrienols; Vitamin E

2010
α-Tocotrienol inhibits osteoclastic bone resorption by suppressing RANKL expression and signaling and bone resorbing activity.
    Biochemical and biophysical research communications, 2011, Mar-25, Volume: 406, Issue:4

    Topics: Animals; Bone Resorption; Cell Differentiation; Cell Survival; Cells, Cultured; Mice; Osteoclasts; RANK Ligand; Signal Transduction; Tocotrienols; Vitamin E

2011
Role of immunoregulatory transcription factors in differential immunomodulatory effects of tocotrienols.
    Free radical biology & medicine, 2011, Jul-01, Volume: 51, Issue:1

    Topics: Animals; Cell Cycle; Cell Proliferation; Cells, Cultured; Chromans; Concanavalin A; Cytokines; Glutathione; Immunologic Factors; Lymphocyte Activation; Mice; NF-kappa B; T-Lymphocytes; Tocotrienols; TOR Serine-Threonine Kinases; Transcription Factor AP-1; Vitamin E

2011
α-Tocotrienol quinone modulates oxidative stress response and the biochemistry of aging.
    Bioorganic & medicinal chemistry letters, 2011, Jun-15, Volume: 21, Issue:12

    Topics: Aging; Animals; Antioxidants; Benzoquinones; Cells, Cultured; Dogs; Dose-Response Relationship, Drug; Humans; Mice; Molecular Structure; Oxidative Stress; Rats; Tocotrienols; Vitamin E

2011
Natural vitamin E α-tocotrienol protects against ischemic stroke by induction of multidrug resistance-associated protein 1.
    Stroke, 2011, Volume: 42, Issue:8

    Topics: Animals; Antioxidants; Brain Ischemia; Cell Death; Cerebral Cortex; Male; Mice; Multidrug Resistance-Associated Proteins; Neurons; Neuroprotective Agents; Stroke; Tocotrienols; Vitamin E

2011
Inhibitory effects of palm α-, γ- and δ-tocotrienol on lipopolysaccharide-induced nitric oxide production in BV2 microglia.
    Cellular immunology, 2011, Volume: 271, Issue:2

    Topics: Animals; Antioxidants; Cell Line; Cell Survival; Chromans; Lipopolysaccharides; Mice; Microglia; Nitric Oxide; Palm Oil; Plant Oils; Tocotrienols; Vitamin E

2011
Tissue distribution of α- and γ-tocotrienol and γ-tocopherol in rats and interference with their accumulation by α-tocopherol.
    Lipids, 2012, Volume: 47, Issue:2

    Topics: alpha-Tocopherol; Animals; Antioxidants; Carrier Proteins; Chromans; gamma-Tocopherol; Male; Rats; Rats, Wistar; Tissue Distribution; Tocotrienols; Vitamin E

2012
Tocotrienols prevent hydrogen peroxide-induced axon and dendrite degeneration in cerebellar granule cells.
    Free radical research, 2012, Volume: 46, Issue:2

    Topics: Animals; Autophagy; Axons; Cells, Cultured; Cerebellum; Chromans; Dendrites; Free Radical Scavengers; Hydrogen Peroxide; Intercellular Signaling Peptides and Proteins; Lipid Peroxidation; Mice; Mice, Inbred C57BL; Microtubule-Associated Proteins; Nerve Degeneration; Nerve Tissue Proteins; Neuroprotective Agents; Primary Cell Culture; Thiobarbituric Acid Reactive Substances; Tocotrienols; Vitamin E

2012
Induction of DNA damage and caspase-independent programmed cell death by vitamin E.
    Nutrition and cancer, 2012, Volume: 64, Issue:1

    Topics: Apoptosis; Caspase 3; Caspases; Cell Line, Tumor; DNA Damage; Drug Screening Assays, Antitumor; Etoposide; Humans; Isomerism; Male; Poly(ADP-ribose) Polymerases; Polyethylene Glycols; Prostatic Neoplasms; Tocotrienols; Vitamin E

2012
Alpha-tocotrienol is the most abundant tocotrienol isomer circulated in plasma and lipoproteins after postprandial tocotrienol-rich vitamin E supplementation.
    Nutrition journal, 2012, Jan-17, Volume: 11

    Topics: Adult; Dietary Supplements; Female; Humans; Lipoproteins; Lipoproteins, HDL; Male; Palm Oil; Plant Oils; Postprandial Period; Tocopherols; Tocotrienols; Vitamin E

2012
Tissue distribution of vitamin E metabolites in rats after oral administration of tocopherol or tocotrienol.
    Journal of nutritional science and vitaminology, 2011, Volume: 57, Issue:5

    Topics: 14-alpha Demethylase Inhibitors; Administration, Oral; alpha-Tocopherol; Animals; Biological Transport; Chromans; gamma-Tocopherol; Intestine, Small; Kidney; Liver; Male; Organ Specificity; Propionates; Rats; Rats, Wistar; Tocotrienols; Vitamin E

2011
δ- and γ-tocotrienols induce classical ultrastructural apoptotic changes in human T lymphoblastic leukemic cells.
    Microscopy and microanalysis : the official journal of Microscopy Society of America, Microbeam Analysis Society, Microscopical Society of Canada, 2012, Volume: 18, Issue:3

    Topics: Apoptosis; Cell Line, Tumor; Cell Nucleus; Cell Survival; Chromans; Chromatin; Humans; Microscopy, Electron, Transmission; T-Lymphocytes; Tocotrienols; Vitamin E

2012
A key regulator of cholesterol homoeostasis, SREBP-2, can be targeted in prostate cancer cells with natural products.
    The Biochemical journal, 2012, Sep-01, Volume: 446, Issue:2

    Topics: Animals; Antineoplastic Agents, Phytogenic; Cell Line, Tumor; Cell Survival; CHO Cells; Cholesterol; Chromans; Cricetinae; Cricetulus; Humans; Intracellular Signaling Peptides and Proteins; Liver X Receptors; Male; Membrane Proteins; Mutant Proteins; Neoplasm Proteins; Orphan Nuclear Receptors; Prostatic Neoplasms; Recombinant Proteins; Sterol Regulatory Element Binding Protein 2; Tocotrienols; Triterpenes; Vitamin E

2012
Increased α-tocotrienol content in seeds of transgenic rice overexpressing Arabidopsis γ-tocopherol methyltransferase.
    Transgenic research, 2013, Volume: 22, Issue:1

    Topics: Antioxidants; Arabidopsis; Gene Expression Regulation, Plant; Methyltransferases; Oryza; Plants, Genetically Modified; Protein Isoforms; Seeds; Tocopherols; Tocotrienols; Vitamin E

2013
Classification and prediction of clinical diagnosis of Alzheimer's disease based on MRI and plasma measures of α-/γ-tocotrienols and γ-tocopherol.
    Journal of internal medicine, 2013, Volume: 273, Issue:6

    Topics: Aged; Alzheimer Disease; Biomarkers; Chromans; Chromatography, High Pressure Liquid; Diagnosis, Differential; Disease Progression; Female; gamma-Tocopherol; Humans; Magnetic Resonance Imaging; Male; Prognosis; Reproducibility of Results; Severity of Illness Index; Tocotrienols; Vitamin E

2013
Tocotrienols promote apoptosis in human breast cancer cells by inducing poly(ADP-ribose) polymerase cleavage and inhibiting nuclear factor kappa-B activity.
    Cell proliferation, 2013, Volume: 46, Issue:2

    Topics: Antineoplastic Agents, Phytogenic; Apoptosis; Breast Neoplasms; Cell Count; Cell Proliferation; Chromans; DNA Fragmentation; Enzyme-Linked Immunosorbent Assay; Female; Humans; Inhibitory Concentration 50; MCF-7 Cells; NF-kappa B p50 Subunit; Paclitaxel; Palm Oil; Plant Oils; Poly (ADP-Ribose) Polymerase-1; Poly(ADP-ribose) Polymerases; Proteolysis; Reagent Kits, Diagnostic; Signal Transduction; Tocotrienols; Vitamin E

2013
Rice bran extract protects from mitochondrial dysfunction in guinea pig brains.
    Pharmacological research, 2013, Volume: 76

    Topics: Animals; Brain; Chromans; Guinea Pigs; Male; Membrane Potential, Mitochondrial; Mitochondria; Oryza; Oxidative Stress; PC12 Cells; Plant Extracts; Rats; Tocotrienols; Vitamin E

2013
Vitamin E analyses in seeds reveal a dominant presence of tocotrienols over tocopherols in the Arecaceae family.
    Phytochemistry, 2013, Volume: 95

    Topics: alpha-Tocopherol; Arecaceae; Seeds; Tocotrienols; Vitamin E

2013
Neuroprotective effects of α-tocotrienol on kainic acid-induced neurotoxicity in organotypic hippocampal slice cultures.
    International journal of molecular sciences, 2013, Sep-05, Volume: 14, Issue:9

    Topics: Animals; Cell Death; Hippocampus; In Situ Nick-End Labeling; In Vitro Techniques; Kainic Acid; Neuroprotective Agents; Rats; Rats, Sprague-Dawley; Thiobarbituric Acid Reactive Substances; Tocotrienols; Vitamin E

2013
Tocopherol and tocotrienol contents of different varieties of rice in Malaysia.
    Journal of the science of food and agriculture, 2015, Mar-15, Volume: 95, Issue:4

    Topics: alpha-Tocopherol; beta-Tocopherol; Chromatography, High Pressure Liquid; Chromatography, Reverse-Phase; Crops, Agricultural; Food Handling; Humans; Hydrolysis; Liquid-Liquid Extraction; Malaysia; Nutritive Value; Oryza; Pigments, Biological; Reproducibility of Results; Seeds; Species Specificity; Tocopherols; Tocotrienols

2015
Stability of α-tocotrienol and α-tocopherol in salami-type sausages and curing brine depending on nitrite and pH.
    Meat science, 2014, Volume: 98, Issue:4

    Topics: alpha-Tocopherol; Animals; Food Preservation; Hydrogen-Ion Concentration; Meat Products; Nitrites; Salts; Swine; Tocotrienols

2014
Kinetic study of the quenching reaction of singlet oxygen by α-, β-, γ-, δ-tocotrienols, and palm oil and soybean extracts in solution.
    Bioscience, biotechnology, and biochemistry, 2014, Volume: 78, Issue:12

    Topics: Carotenoids; Chromans; Free Radical Scavengers; Glycine max; Kinetics; Palm Oil; Plant Extracts; Plant Oils; Singlet Oxygen; Solutions; Tocopherols; Tocotrienols; Vitamin E

2014
Cytotoxicity and apoptotic activities of alpha-, gamma- and delta-tocotrienol isomers on human cancer cells.
    BMC complementary and alternative medicine, 2014, Dec-06, Volume: 14

    Topics: Adenocarcinoma; Adenocarcinoma of Lung; Antineoplastic Agents; Antioxidants; Apoptosis; bcl-2-Associated X Protein; BH3 Interacting Domain Death Agonist Protein; Caspase 8; Cell Cycle; Cell Line, Tumor; Cell Survival; Central Nervous System Neoplasms; Chromans; Cytochromes c; DNA Fragmentation; Glioblastoma; Humans; Isomerism; Lung Neoplasms; Mitochondria; Tocotrienols; Vitamin E

2014
Control of macaw palm seed germination by the gibberellin/abscisic acid balance.
    Plant biology (Stuttgart, Germany), 2015, Volume: 17, Issue:5

    Topics: Abscisic Acid; alpha-Tocopherol; Arecaceae; Cyclopentanes; Cytokinins; Germination; Gibberellins; Lipid Peroxidation; Oxylipins; Plant Growth Regulators; Seeds; Tocotrienols

2015
Antioxidant capacity and vitamin E in barley: Effect of genotype and storage.
    Food chemistry, 2015, Nov-15, Volume: 187

    Topics: alpha-Tocopherol; Antioxidants; Ascorbic Acid; Food Storage; Genotype; Hordeum; Tocotrienols; Vitamin E

2015
Anti-inflammatory γ- and δ-tocotrienols improve cardiovascular, liver and metabolic function in diet-induced obese rats.
    European journal of nutrition, 2017, Volume: 56, Issue:1

    Topics: Adipose Tissue; alpha-Tocopherol; Animals; Anti-Inflammatory Agents; Body Composition; Cardiovascular System; Diet, High-Fat; Dietary Carbohydrates; Fatty Liver; Insulin Resistance; Liver; Male; Metabolic Syndrome; Obesity, Abdominal; Organ Size; Rats; Rats, Wistar; Tocotrienols; Vitamin E

2017
Vitamin E analysis by ultra-performance convergence chromatography and structural elucidation of novel α-tocodienol by high-resolution mass spectrometry.
    Food chemistry, 2016, Apr-01, Volume: 196

    Topics: alpha-Tocopherol; Chromans; Chromatography, High Pressure Liquid; Mass Spectrometry; Palm Oil; Plant Oils; Tocotrienols; Vitamin E

2016
Effect of vitamin E on 24(S)-hydroxycholesterol-induced necroptosis-like cell death and apoptosis.
    The Journal of steroid biochemistry and molecular biology, 2017, Volume: 169

    Topics: alpha-Tocopherol; Antioxidants; Apoptosis; Cell Death; Cell Line, Tumor; Cell Survival; Humans; Hydroxycholesterols; Lipids; Microscopy, Fluorescence; Neurons; Reactive Oxygen Species; Tocotrienols; Tretinoin; Vitamin E

2017
Tocotrienols Stimulate Insulin Secretion of Rat Pancreatic Isolated Islets in a Dynamic Culture.
    Current pharmaceutical biotechnology, 2017, Volume: 18, Issue:7

    Topics: Animals; Antioxidants; Chromans; Dose-Response Relationship, Drug; Glucose; In Vitro Techniques; Insulin; Insulin Secretion; Islets of Langerhans; Male; Potassium Chloride; Rats; Rats, Wistar; Tissue Culture Techniques; Tocotrienols; Vitamin E

2017
The Effect of Pressure and Solvent on the Supercritical Fluid Chromatography Separation of Tocol Analogs in Palm Oil.
    Molecules (Basel, Switzerland), 2017, Aug-29, Volume: 22, Issue:9

    Topics: alpha-Tocopherol; Chromans; Chromatography, Supercritical Fluid; Molecular Structure; Palm Oil; Pressure; Solvents; Tocopherols; Tocotrienols; Vitamin E

2017
Induction of peroxisomal changes in oligodendrocytes treated with 7-ketocholesterol: Attenuation by α-tocopherol.
    Biochimie, 2018, Volume: 153

    Topics: alpha-Tocopherol; Animals; Apoptosis; Dose-Response Relationship, Drug; Fatty Acids; Fibroblasts; Humans; Ketocholesterols; Male; Membrane Potential, Mitochondrial; Membrane Proteins; Mice; Mitochondria; Oligodendroglia; Peroxisomes; Plasmalogens; Tocotrienols; Zellweger Syndrome

2018
Suppression of Amyloid-β Adsorption on Endoplasmic Reticulum Stress-Mimicking Membranes by α-Tocopherol and α-Tocotrienol.
    The journal of physical chemistry letters, 2022, Dec-29, Volume: 13, Issue:51

    Topics: Adsorption; alpha-Tocopherol; Alzheimer Disease; Amyloid beta-Peptides; Endoplasmic Reticulum Stress; Humans; Tocotrienols; Vitamin E

2022
α-Tocotrienol and Redox-Silent Analogs of Vitamin E Enhances Bortezomib Sensitivity in Solid Cancer Cells through Modulation of NFE2L1.
    International journal of molecular sciences, 2023, May-27, Volume: 24, Issue:11

    Topics: Antineoplastic Agents; Bortezomib; Cell Line, Tumor; Drug Resistance, Neoplasm; Neoplasms; Oxidation-Reduction; Proteasome Endopeptidase Complex; Proteasome Inhibitors; Vitamin E

2023