d-alpha tocopherol has been researched along with squalene in 137 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 8 (5.84) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 20 (14.60) | 29.6817 |
| 2010's | 99 (72.26) | 24.3611 |
| 2020's | 10 (7.30) | 2.80 |
| Authors | Studies |
|---|---|
| Beck, FW; Orr, KJ; Pearson, CM; Whitehouse, MW | 1 |
| Gutfinger, T; Letan, A | 1 |
| Dada, OA; Threlfall, DR; Whistance, GR | 1 |
| Goodwin, TW; Threlfall, DR; Whistance, GR | 1 |
| Imaeda, K; Matsukawa, R; Ohsawa, K; Watanabe, T; Yoshimura, Y | 1 |
| Dillard, CJ; Kunert, KJ; Tappel, AL | 1 |
| Morin, RJ; Srikantaiah, MV | 1 |
| D'Ambrosio, M; Finotti, E; Paoletti, F; Quaglia, G; Vivanti, V | 1 |
| Hsieh, SN; Packer, L; Podda, M; Schroeter, C; Thiele, JJ | 1 |
| Gylling, H; Miettinen, TA; Relas, H | 1 |
| Giacometti, J | 1 |
| Psomiadou, E; Tsimidou, M | 2 |
| De Pità, O; Littarru, GP; Passi, S; Puddu, P | 1 |
| De Simone, F; Ippolito, F; Passi, S; Rastrelli, L; Vacca, G | 1 |
| Bernhardt, J; Bertram, HJ; Engelhart, K; Ley, JP | 1 |
| Matterson, LD; Olson, G; Pudelkiewicz, WJ | 1 |
| Cert, A; Domínguez, MM; Espartero, JL; Mateos, R | 1 |
| De Pità, O; Grandinetti, M; Littarru, GP; Passi, S; Simotti, C | 1 |
| Ekanayake-Mudiyanselage, S; Kraemer, K; Thiele, JJ | 1 |
| Choo, YM; Chuah, CH; Hashim, MA; Ma, AN; Ng, MH | 1 |
| Devaki, T; Senthilkumar, S; Subashini, R; Yogeeta, SK | 1 |
| Kalinova, J; Triska, J; Vrchotova, N | 1 |
| Shibamoto, T; Wei, A | 1 |
| Arlorio, M; Barra, A; Cabras, P; Cereti, E; Coisson, JD; Dessi, S; Garau, VL; Sarais, G | 1 |
| Wertz, PW | 1 |
| Fang, JY; Huang, ZR; Lin, YK | 1 |
| Brosh, A; Eitam, H; Hadar, Y; Izhaki, I; Kerem, Z; Orlov, A; Shabtay, A; Tadmor, Y | 1 |
| Allen, RJ; Andrews, N; Casey, M; Collinson, AC; Eccleston, PE; Faust, SN; Finn, A; Heath, PT; Hoschler, K; John, T; Ladhani, S; Miller, E; Oeser, C; Okike, I; Pollard, AJ; Reiner, A; Sheasby, E; Snape, MD; Waddington, CS; Waight, P; Walker, WT; Wilkins, S | 1 |
| Arístegui, J; Carmona, A; Dieussaert, I; Gillard, P; Merino, JM; Omeñaca, F; Tejedor, JC; Vaman, T | 1 |
| Kawakami, K; Maruko, T; Miyazawa, T; Nakagawa, K; Nishida, H; Shibata, A; Sookwong, P; Tsuduki, T | 1 |
| Allen, R; Andrews, N; Casey, M; Collinson, A; Eccleston, P; Faust, S; Finn, A; Heath, P; Hoschler, K; John, T; Ladhani, S; Miller, E; Oeser, C; Okike, I; Pollard, A; Reiner, A; Sheasby, E; Snape, M; Waddington, C; Waight, P; Walker, W; Wilkins, S | 1 |
| Akselsen, PE; Cox, RJ; Jul-Larsen, A; Madhun, AS; Major, D; Mohn, K; Nilsen, M; Nøstbakken, JK; Pedersen, G; Sjursen, H; Smith, I; Svindland, S; Wood, J | 1 |
| Bate, J; Heath, PT; Hoschler, K; Miller, E; Morden, J; Sheasby, L; Taj, M; Yung, CF | 1 |
| Faust, SN; Walker, WT | 1 |
| Andrews, N; Miller, E; Waight, P; Yung, CF | 1 |
| Brosset, C; Javelle, E; Lorcy, S; Simon, F; Soulier, B | 1 |
| Baras, B; Bourguignon, P; Carlsen, H; Chomez, P; Delhaye, S; Didierlaurent, A; Elouahabi, A; Garçon, N; Harvengt, P; Jacob, V; Kielland, A; Morel, S; Planty, C; Van Mechelen, M | 1 |
| Alves, D; Bart, PA; Calandra, T; Cavassini, M; Ellefsen, K; Giulieri, S; Hoschler, K; Manuel, O; Pascual, M; Venetz, JP | 1 |
| Aristegui, J; Behre, U; Caplanusi, A; Carmona, A; Dieussaert, I; Garcia-Sicilia, J; Gillard, P; Merino, JM; Tejedor, JC; Vaman, T | 1 |
| Bennett, A; Butter, N; Doerholt, K; Donaghy, S; Heath, PT; Hoschler, K; Ladhani, S; Miller, E; Oeser, C; Okike, IO; Sheasby, L; Storey, S; Yung, C | 1 |
| Allen, R; Andrews, NJ; Casey, M; Chalk, J; Collinson, AC; Faust, SN; Fineman, N; Finn, A; Fletcher, M; Heath, PT; Hoschler, K; John, T; Kerridge, S; Ladhani, S; Michaelis, L; Miller, E; Oeser, C; Okike, I; Pollard, AJ; Reiner, A; Sheasby, L; Snape, MD; Waddington, C; Waight, PA; Walker, WT; Wilkins, S | 1 |
| Abramowicz, D; Brochier, B; Broeders, NE; De Mul, A; Gastaldello, K; Hombrouck, A; Lemy, A; Massart, A; Racapé, J; Thomas, I; Van Gucht, S; Weichselbaum, L; Wissing, KM | 1 |
| Bel, M; Calmy, A; Combescure, C; Delhumeau, C; Hirschel, B; Kaiser, L; Meier, S; Nguyen, A; Siegrist, CA; Yerly, S | 1 |
| Didierlaurent, AM; Garçon, N; Vaughn, DW | 1 |
| Aavitsland, P; Borgen, K; Feiring, B; Guzmán Herrador, BR; Riise Bergsaker, MA | 1 |
| Dobson, S; Halperin, SA; Kellner, JD; Kollman, T; Kuhn, S; Langley, JM; Li, Y; MacKinnon-Cameron, D; McNeil, S; Quach, C; Scheifele, DW; Smith, B; Vanderkooi, OG; Ward, B | 1 |
| Aggarwal, N; Connor, D; Garfield, H; Gupta, A; Langley, JM; Lebel, MH; Li, P; Madan, A; Reich, D; Vaughn, DW | 1 |
| Ikematsu, H; Li, P; Madan, A; Tenjinbaru, K; Vaughn, D | 1 |
| Aboulker, JP; Delfraissy, JF; Desaint, C; Durier, C; Girard, PM; Launay, O; Lévy, Y; Lucht, F; May, T; Michelet, C; Rami, A; Roman, F | 1 |
| Kronborg, G; Nielsen, AB; Nielsen, HS; Nielsen, L; Thybo, S | 1 |
| Ishii, KJ; Tetsutani, K | 1 |
| Chu, L; Frenette, L; Halperin, S; Langley, JM; Li, P; McNeil, S; Vaughn, D | 1 |
| Augustine, G; Bugg, G; Davis, Y; Enstone, J; Hoschler, K; Konje, J; Myles, P; Nguyen-Van-Tam, J; Nicholson, K; Puleston, R; Stephenson, I; Thornton, J; Zambon, M | 1 |
| Beran, J; Caplanusi, A; Claeys, C; Devaster, JM; Durand, C; Duval, X; El Idrissi, M; Esen, M; Falsey, AR; Feldman, G; Frey, SE; Galtier, F; Hwang, SJ; Innis, BL; Kovac, M; Kremsner, P; Launay, O; Leroux-Roels, G; McElhaney, JE; McNeil, S; Nowakowski, A; Oostvogels, L; Richardus, JH; Ruiz-Palacios, GM; Trofa, A; van Essen, GA | 1 |
| Ledgerwood, JE | 1 |
| Bambure, V; Gillard, P; Hanon, E; Kafeja, F; Moris, P; Roman, F; Van Damme, P | 1 |
| Bruun Laursen, A | 1 |
| Aggarwal, N; Dionne, M; Godeaux, O; Kyle, M; Li, P; Madariaga, M; Vaughn, DW; Yang, WH | 1 |
| Fox, CB; Haensler, J | 1 |
| De Serres, G; Drolet, JP; Gagnon, R; Landry, M; Ménard, S; Ouakki, M; Rouleau, I; Skowronski, DM; Toth, E | 1 |
| Andrews, NJ; Faust, SN; Finn, A; Hoschler, K; Miller, E; Pollard, AJ; Snape, MD; Walker, WT; Zambon, M | 1 |
| Berglund, J; Boutriau, D; Lestrate, P; Tavares Da Silva, F; Vink, P | 1 |
| Li, P; Poder, A; Roy-Ghanta, S; Simurka, P; Vaughn, D | 1 |
| Ahmed, SS; MacDonald, NE; Schur, PH; Steinman, L | 1 |
| Chu, DW; Dramé, M; Gillard, P; Hwang, SJ; Lim, FS; Roman, F; Thongcharoen, P; Walravens, K; Yang, PC | 1 |
| Girod, A; Weyermann, C | 1 |
| Cooper, C; Gipson, E; Haase, D; Halperin, S; Klein, M; Scheifele, D; Walmsley, S; Ward, BJ; Yam, KK | 1 |
| Allwinn, R; Bickel, M; Brodt, HR; Doerr, HW; Herrmann, E; Jung, O; Kroon, FP; Lais, C; Stephan, C; Wieters, I | 1 |
| Bankwitz, D; Brovko, O; Fiedler, M; Khudyakov, Y; Lange, M; Nassal, M; Osburn, W; Pietschmann, T; Pumpens, P; Roggendorf, M; Timm, J; Viazov, S; Walker, A; Zekri, AR | 1 |
| Del Giudice, G; Rappuoli, R | 1 |
| Morishita, K; Nishimura, M; Nishiyama, K; Sakakibara, Y; Suiko, M; Yamasaki, M | 1 |
| De Wals, P; Deceuninck, G; Desautels, A; Mignot, E; Montplaisir, J; Ouakki, M; Petit, D; Quinn, MJ | 1 |
| Drame, M; Frenette, L; Godeaux, O; Innis, BL; Izurieta, P; Jeanfreau, R; Kosalaraksa, P; Madariaga, M; Vaughn, DW | 1 |
| Dramé, M; Giet, D; Gillard, P; Heijmans, S; Roman, F; Walravens, K | 1 |
| Asanza, M; Guerrini, A; Maietti, S; Neill, D; Radice, M; Sacchetti, G; Viafara, D | 1 |
| Boutet, P; Carmona Martinez, A; Devaster, JM; Salamanca de la Cueva, I; Smolenov, I; Vanden Abeele, C | 1 |
| Chu, L; Dramé, M; Frenette, L; Fries, L; Halperin, SA; Jeanfreau, R; Kyle, M; Langley, JM; McNeil, S; Moris, P; Vaughn, DW | 1 |
| Cohet, C; Dewe, W; Drame, M; Fries, LF; Hepburn, A; Innis, BL; Li, P; Seifert, H; Vaughn, DW | 1 |
| Aladedunye, F; Matthaus, B; Przybylski, R | 1 |
| Baldó, JM; Díez-Domingo, J; Garcés-Sánchez, M; Garcia-Corbeira, P; Gillard, P; Jubert-Rosich, A; Marès, J; Moris, P; Planelles-Catarino, MV; Teko, M; Ubeda, I; Vanden Abeele, C | 1 |
| Mitkus, RJ; Tegenge, MA | 1 |
| Crumpton, JC; Debeauchamp, J; Kaplan, B; Kercher, L; Krauss, S; Seiler, P; Sun, Y; Tang, L; Webby, RJ; Webster, R; Wong, SS; Zanin, M | 1 |
| Boutriau, D; Damaso, S; Haelterman, E; Lestrate, P; Levy, J; Licini, L; Moris, P; Van Belle, P | 1 |
| Drame, M; Innis, BL; Schuind, A; Segall, N | 1 |
| Destexhe, E; Didierlaurent, AM; Garçon, N; Gautier, G; Kuper, F; Le Gal, J; Martin, T; Morelle, D; Segal, L; Wouters, S | 1 |
| Chaudhuri, TK; Dey, P; Ray, S; Sarkar, MP | 1 |
| Dramé, M; Izurieta, P; Kim, WJ; Lee, J; Lee, JS; Schuind, A; Vaughn, DW; Wie, SH | 1 |
| Cox, RJ; Jul-Larsen, Å; Lartey, S; Montomoli, E; Pathirana, RD; Wood, J; Zhou, F | 1 |
| Bambure, V; Berglund, J; Caplanusi, A; Dieussaert, I; Flodmark, CE; Korhonen, T; Lindstrand, A; Richardus, JH; Roy-Ghanta, S; Silfverdal, SA; Vaughn, DW; Vesikari, T | 1 |
| Baras, B; Beaulieu, E; Giannini, SL; Innis, BL; Joly, MH; Katz, JM; Levine, MZ; Liu, F; Lu, X; Mallett, CP | 1 |
| Arístegui, J; Bambure, V; Caplanusi, A; Carmona, A; Dieussaert, I; García-Corbeira, P; Garcia-Sicilia, J; Gillard, P; Merino, JM; Moris, P; Omeñaca, F; Tejedor, JC; Walravens, K | 1 |
| Anderson, EL; Atmar, RL; Bellamy, AR; Berry, AA; Campbell, JD; Creech, CB; Edwards, KM; El Sahly, HM; Frey, SE; Graham, I; Gutierrez, AF; Hill, H; Jackson, LA; Keitel, WA; Kotloff, KL; Noah, DL; Patel, SM; Thomsen, IP | 1 |
| Bédard, F; De Serres, G; Dupré, N; Lacroix, K; Landry, M; Ouakki, M; Rouleau, I; Skowronski, DM; Toth, E | 1 |
| Baum, U; Gissler, M; Jokinen, J; Kilpi, T; Leino, T | 1 |
| Fukuda, T; Ichikawa, M; Kimachi, K; Kino, Y; Naruse, T; Oda, Y; Tanabe, T; Tochihara, S; Ueda, K | 1 |
| Dramé, M; Izurieta, P; Uy-Aragon, MJ; Vaughn, DW | 1 |
| Chen, WH; Creech, CB; Edwards, KM; Hill, H; Jackson, LA; Keitel, WA; Kotloff, KL; Mangal, B; Noah, DL; Patel, SM | 1 |
| Baay, M; Bollaerts, K; Stassijns, J; Verstraeten, T | 1 |
| Allen, EK; Beaulieu, É; Burt, DS; Burt, KR; Gupta, J; Mallett, CP; Ward, BJ; Yam, KK | 1 |
| Elizabeth Halloran, M; Feldstein, LR; Keitel, WA; Longini, IM; Matrajt, L | 1 |
| Hertz, T; Johnson, C; Karlsson, EA; Krammer, F; Mehle, A; Schultz-Cherry, S | 1 |
| Ferguson, M; Frenette, L; Friel, D; Innis, BL; Kroll, R; Li, P; Madan, A; Schuind, A; Segall, N; Soni, J | 1 |
| Benoit, A; Beran, J; Claeys, C; Devaster, JM; Dewé, W; Durand, C; Duval, X; Esen, M; Falsey, AR; Feldman, G; Galtier, F; Gervais, P; Hwang, SJ; Launay, O; Leroux-Roels, G; McElhaney, JE; McNeil, S; Oostvogels, L; Richardus, JH; Ruiz-Palacios, GM; Trofa, A; van Essen, GA | 1 |
| Beaulieu, É; Bleau, V; Brewer, A; Mallett, CP; Ward, BJ; Yam, KK | 1 |
| Galson, JD; Kelly, DF; Trück, J; van der Most, R | 1 |
| Ambra, R; Forte, V; Lucchetti, S; Natella, F; Pastore, G | 1 |
| Airenne, K; He, F; Julkunen, I; Kakkola, L; Karlberg, H; Melén, K; Mirazimi, A; Vapalahti, O | 1 |
| Choo, YM; Loganathan, R; Radhakrishnan, AK; Subramaniam, KM; Teng, KT | 1 |
| Chu, L; Ferguson, M; Friel, D; Innis, BL; Li, P; Madan, A; Rheault, P; Schuind, A; Segall, N; Sheldon, E; Soni, J; Toma, A | 1 |
| Ferguson, M; Friel, D; Innis, BL; Li, P; Madan, A; Rheault, P; Schuind, A; Seiden, D; Soni, J; Toma, A | 1 |
| Barbeau, DM; Bauchau, V; Cohet, C; Dos Santos, G; Seifert, HA; Shinde, V | 1 |
| Harvanová, J; Ondrejka, R; Ondrejková, A; Prokeš, M; Süli, J | 1 |
| Chu, L; Collins, H; Drame, M; Frenette, L; Friel, D; Innis, BL; Madan, A; Schuind, A; Sheldon, E; Vaughn, DW | 1 |
| Bach, TJ; Chen, X; Chye, ML; Liao, P; Wang, M | 1 |
| Del Giudice, G; Didierlaurent, AM; Rappuoli, R | 1 |
| Harandi, AM | 1 |
| Creech, CB; Edwards, KM; Gelber, CE; Goll, JB; Hoek, KL; Howard, LM; Jensen, TL; Joyce, S; Levy, SE; Link, AJ; Prasad, N | 1 |
| Bauchau, V; Bekkat-Berkani, R; Cohet, C; Doherty, TM; Garçon, N; Innis, BL; Rappuoli, R; Schuind, A; Tavares Da Silva, F; van der Most, R | 1 |
| Liang, Z; Ma, X; Shi, S; Sun, B; Xia, X; Zhu, H | 1 |
| Gul, RM; Li, ZM; Ren, Y; Wang, FY; Wang, J; Wei, ST; Wei, X; Xu, JZ; Xu, L | 1 |
| Endo, Y; Zeng, W | 1 |
| Dwyer, DE; Hauser, MI; Muscatello, DJ; Soh, ACY; Turner, RM | 1 |
| Anderson, SA; Beland, FA; Forshee, RA; Mitkus, RJ; Tegenge, MA; Vanlandingham, MM; Von Tungeln, LS | 1 |
| Ayachit, G; Bhairappanavar, SB; Das, J; Jani, B; Joshi, C; Shaikh, I; Sharma, P; Shukla, L | 1 |
| Amiji, MM; Bertholet, S; Friedrich, K; Henson, D; Kanitkar, AP; Lodaya, RN; Mallett, CP; Nuti, S; O'Hagan, DT; Yamagata, R | 1 |
| Brusini, R; Cailleau, C; Couvreur, P; Dormont, F; Gaudin, F; Gendron, A; Mougin, J; Peramo, A; Reynaud, F; Varna, M | 1 |
| Endo, M; Fukuda, T; Hayashida, K; Ibaragi, K; Kino, Y; Naruse, T; Tanabe, T; Tanishima, M; Ueda, K | 1 |
| Andrews, N; Gringras, P; Miller, E; Quinnell, T; Shneerson, J; Stowe, J; Zaiwalla, Z | 1 |
| Kamani, MH; Luithui, Y; Meera, MS; Sreerama, YN | 1 |
| Ashuach, T; Bosinger, SE; Chang, SE; Cheung, P; Cortese, M; Davis, M; De Jong, SE; Donato, M; Dvorak, M; Foecke, MH; Gupta, S; Hagan, T; Khatri, P; Kuo, A; Li, C; Maecker, HT; Pulendran, B; Rouphael, N; Subramaniam, S; Utz, PJ; van der Most, R; Wimmers, F; Yosef, N | 1 |
| Destexhe, E; Dubé, C; Landry, N; Paris-Robidas, S; Primakova, I; Trépanier, S; Ward, BJ | 1 |
| Andreani, G; Arunachalam, PS; Aye, PP; Blair, RV; Bohm, RP; Boyd, SD; Charland, N; D'Aoust, MA; Dubé, C; Fontenot, J; Gobeil, P; Golden, N; Landry, N; Lehmicke, G; Monjure, C; Pillet, S; Pulendran, B; Rappaport, J; Röltgen, K; Russell-Lodrigue, K; Trépanier, S; Villinger, F; Ward, BJ | 1 |
| Buddy Creech, C; Chen, WH; Cross, K; Dickey, M; Goepfert, PA; Logan, HL; Neuzil, KM; Ortiz, JR; Overton, ET; Parker, S; Spearman, PW; Wegel, A | 1 |
| Boguś, MI; Drozdowski, M; Gołębiowski, M; Kaczmarek, A; Sobich, J; Wrońska, AK; Włóka, E | 1 |
| Asaoka, Y; Hashimoto, M; Hayashi, T; Hayata, A; Hirose, J; Ishida, S; Ishii, KJ; Kobiyama, K; Nagira, M; Nakagawa, T; Nishinaka, A; Omoto, S; Onishi, M; Tajiri, M; Yanagida, Y; Yoshioka, Y | 1 |
16 review(s) available for d-alpha tocopherol and squalene
| Article | Year |
|---|---|
The antioxidant network of the stratum corneum.
Topics: Aging; Air Pollutants; Animals; Antioxidants; Arm; Ascorbic Acid; Benzoyl Peroxide; Catalase; Cheek; Epidermis; Glutathione; Guinea Pigs; Humans; Keratinocytes; Lipid Peroxidation; Oxidants; Ozone; Photochemistry; Proteins; Radiation Injuries; Sebum; Squalene; Ultraviolet Rays; Uric Acid; Vitamin E | 2001 |
Biological and pharmacological activities of squalene and related compounds: potential uses in cosmetic dermatology.
Topics: Animals; Antioxidants; beta Carotene; Cosmetics; Dermatology; Emollients; Emulsions; Humans; Lipids; Molecular Structure; Oxidation-Reduction; Plant Oils; Skin; Squalene; Ubiquinone; Vitamin A; Vitamin E; Vitamin K 1; Vitamins | 2009 |
Monovalent inactivated split-virion AS03-adjuvanted pandemic influenza A (H1N1) vaccine.
Topics: alpha-Tocopherol; Drug Combinations; Humans; Influenza A Virus, H1N1 Subtype; Influenza Vaccines; Influenza, Human; Polysorbates; Squalene; Vaccines, Inactivated; Vaccines, Subunit | 2010 |
Development and evaluation of AS03, an Adjuvant System containing α-tocopherol and squalene in an oil-in-water emulsion.
Topics: Adjuvants, Immunologic; alpha-Tocopherol; Animals; Antigens; Drug Combinations; Emulsions; Humans; Influenza Vaccines; Oils; Polysorbates; Squalene; Water | 2012 |
Adjuvants in influenza vaccines.
Topics: Adjuvants, Immunologic; alpha-Tocopherol; Alum Compounds; Drug Combinations; Humans; Influenza Vaccines; Polysorbates; Squalene; Vaccines, Inactivated | 2012 |
An update on safety and immunogenicity of vaccines containing emulsion-based adjuvants.
Topics: Adjuvants, Immunologic; alpha-Tocopherol; Clinical Trials as Topic; Drug Combinations; Emulsions; History, 20th Century; History, 21st Century; Humans; Polysorbates; Product Surveillance, Postmarketing; Squalene; Vaccines | 2013 |
Narcolepsy, 2009 A(H1N1) pandemic influenza, and pandemic influenza vaccinations: what is known and unknown about the neurological disorder, the role for autoimmunity, and vaccine adjuvants.
Topics: Adjuvants, Immunologic; alpha-Tocopherol; Antibodies, Viral; Antigens, Viral; Autoimmunity; Canada; Drug Combinations; Europe; Humans; Influenza A Virus, H1N1 Subtype; Influenza Vaccines; Influenza, Human; Narcolepsy; Pandemics; Polysorbates; Squalene; Vaccination | 2014 |
Inactivated and adjuvanted influenza vaccines.
Topics: Adjuvants, Immunologic; alpha-Tocopherol; Animals; Drug Combinations; Humans; Influenza Vaccines; Polysorbates; Squalene; Vaccines, Inactivated | 2015 |
Performance of antioxidative compounds under frying conditions: A review.
Topics: alpha-Tocopherol; Antioxidants; beta-Tocopherol; Carotenoids; Cooking; Hot Temperature; Lignans; Nutritive Value; Phenylpropionates; Phospholipids; Phytosterols; Plant Extracts; Plant Oils; Polyphenols; Squalene | 2017 |
A systematic review and meta-analysis on the safety of newly adjuvanted vaccines among children.
Topics: Adjuvants, Immunologic; Adolescent; alpha-Tocopherol; Child; Child, Preschool; Clinical Trials as Topic; Drug Combinations; Humans; Infant; Likelihood Functions; Lipid A; Polysorbates; Risk; Saponins; Squalene; Vaccines | 2016 |
Health-promoting effects of red palm oil: evidence from animal and human studies.
Topics: Animals; Antioxidants; Cardiovascular Diseases; Carotenoids; Disease Models, Animal; Evidence-Based Medicine; Fruit; Health Promotion; Humans; Palm Oil; Phytochemicals; Randomized Controlled Trials as Topic; Recommended Dietary Allowances; Squalene; Ubiquinone; Vitamin A Deficiency; Vitamin E | 2017 |
Correlates of adjuvanticity: A review on adjuvants in licensed vaccines.
Topics: Adjuvants, Immunologic; Aged; alpha-Tocopherol; Animals; Drug Combinations; Herpes Zoster; Humans; Immunity, Cellular; Immunity, Humoral; Immunogenicity, Vaccine; Influenza, Human; Liposomes; Papillomavirus Infections; Polysorbates; Squalene; Th1 Cells; Th2 Cells; Viral Vaccines | 2018 |
Systems analysis of human vaccine adjuvants.
Topics: Adjuvants, Immunologic; alpha-Tocopherol; Animals; Drug Combinations; Glucosides; HIV Infections; Humans; Immunity, Innate; Immunogenicity, Vaccine; Influenza, Human; Lipid A; Liposomes; Malaria, Falciparum; Polysorbates; Squalene; Systems Analysis; Systems Biology; T-Lymphocytes, Helper-Inducer; Toll-Like Receptor 4; Vaccines | 2018 |
Safety of AS03-adjuvanted influenza vaccines: A review of the evidence.
Topics: Adjuvants, Immunologic; alpha-Tocopherol; Animals; Antibodies, Viral; Clinical Trials as Topic; Drug Combinations; Hemagglutination Inhibition Tests; Humans; Influenza A Virus, H1N1 Subtype; Influenza Vaccines; Narcolepsy; Pharmacovigilance; Polysorbates; Squalene; Vaccination; Vaccines, Inactivated | 2019 |
Vaccine adjuvants: Understanding the structure and mechanism of adjuvanticity.
Topics: Adaptive Immunity; Adjuvants, Immunologic; alpha-Tocopherol; Animals; Clinical Trials as Topic; Drug Combinations; Humans; Immunogenicity, Vaccine; Polysorbates; Squalene; Structure-Activity Relationship; Vaccines | 2019 |
An indirect comparison meta-analysis of AS03 and MF59 adjuvants in pandemic influenza A(H1N1)pdm09 vaccines.
Topics: Adjuvants, Immunologic; alpha-Tocopherol; Antibodies, Viral; Drug Combinations; Female; Hemagglutination Inhibition Tests; Hemagglutinin Glycoproteins, Influenza Virus; Humans; Influenza A Virus, H1N1 Subtype; Influenza Vaccines; Influenza, Human; Male; Polysorbates; Seroconversion; Squalene; Vaccination | 2019 |
44 trial(s) available for d-alpha tocopherol and squalene
| Article | Year |
|---|---|
Oral supplementation with all-Rac- and RRR-alpha-tocopherol increases vitamin E levels in human sebum after a latency period of 14-21 days.
Topics: Adult; alpha-Tocopherol; Chromatography, High Pressure Liquid; Dietary Supplements; Face; Female; Humans; Lipids; Male; Sebum; Skin; Squalene; Time Factors; Tocopherols; Vitamin E | 2004 |
Safety and immunogenicity of AS03B adjuvanted split virion versus non-adjuvanted whole virion H1N1 influenza vaccine in UK children aged 6 months-12 years: open label, randomised, parallel group, multicentre study.
Topics: Adjuvants, Immunologic; Adolescent; alpha-Tocopherol; Child; Child, Preschool; Drug Combinations; Female; Hemagglutination Inhibition Tests; Humans; Infant; Influenza A Virus, H1N1 Subtype; Influenza Vaccines; Influenza, Human; Male; Polysorbates; Squalene; Virion | 2010 |
Immunogenicity and safety of AS03-adjuvanted 2009 influenza A H1N1 vaccine in children 6-35 months.
Topics: Adjuvants, Immunologic; alpha-Tocopherol; Antibodies, Viral; Antibody Formation; Child, Preschool; Drug Combinations; Female; Hemagglutination Inhibition Tests; Humans; Immunization, Secondary; Infant; Influenza A Virus, H1N1 Subtype; Influenza Vaccines; Influenza, Human; Male; Polysorbates; Squalene | 2010 |
Open-label, randomised, parallel-group, multicentre study to evaluate the safety, tolerability and immunogenicity of an AS03(B)/oil-in-water emulsion-adjuvanted (AS03(B)) split-virion versus non-adjuvanted whole-virion H1N1 influenza vaccine in UK childre
Topics: alpha-Tocopherol; Antibodies, Viral; Child; Child, Preschool; Disease Outbreaks; Drug Combinations; Emulsions; Female; Humans; Immunization Programs; Infant; Influenza A Virus, H1N1 Subtype; Influenza Vaccines; Influenza, Human; Male; Polysorbates; Program Evaluation; Squalene; United Kingdom | 2010 |
Immunogenicity and safety of AS03-adjuvanted H1N1 pandemic vaccines in children and adolescents.
Topics: Adjuvants, Immunologic; Adolescent; alpha-Tocopherol; Antibodies, Viral; Child; Drug Combinations; Female; Germany; Humans; Influenza A Virus, H1N1 Subtype; Influenza Vaccines; Influenza, Human; Male; Pandemics; Polysorbates; Spain; Squalene; Treatment Outcome; Vaccination | 2011 |
Predictors of immune response and reactogenicity to AS03B-adjuvanted split virion and non-adjuvanted whole virion H1N1 (2009) pandemic influenza vaccines.
Topics: Adjuvants, Immunologic; alpha-Tocopherol; Antibodies, Viral; Child; Child, Preschool; Drug Combinations; Female; Hemagglutination Inhibition Tests; Humans; Infant; Influenza A Virus, H1N1 Subtype; Influenza Vaccines; Influenza, Human; Male; Polysorbates; Squalene; Vaccines, Inactivated; Vaccines, Subunit | 2011 |
Safety and immunogenicity of 2010-2011 H1N12009-containing trivalent inactivated influenza vaccine in children 12-59 months of age previously given AS03-adjuvanted H1N12009 pandemic vaccine: a PHAC/CIHR Influenza Research Network (PCIRN) study.
Topics: Adjuvants, Immunologic; alpha-Tocopherol; Antibodies, Viral; Canada; Child, Preschool; Drug Combinations; Drug-Related Side Effects and Adverse Reactions; Female; Humans; Infant; Influenza A Virus, H1N1 Subtype; Influenza Vaccines; Interviews as Topic; Male; Polysorbates; Prospective Studies; Squalene; Vaccines, Inactivated | 2012 |
Randomized, multicenter trial of a single dose of AS03-adjuvanted or unadjuvanted H1N1 2009 pandemic influenza vaccine in children 6 months to <9 years of age: safety and immunogenicity.
Topics: Adjuvants, Immunologic; alpha-Tocopherol; Child; Child, Preschool; Cohort Studies; Drug Combinations; Female; Hemagglutination Inhibition Tests; Humans; Infant; Influenza A Virus, H1N1 Subtype; Influenza Vaccines; Influenza, Human; Male; Neutralization Tests; Pandemics; Polysorbates; Squalene; Tocopherols; Vaccination | 2012 |
Evaluation of immune response following one dose of an AS03A-adjuvanted H1N1 2009 pandemic influenza vaccine in Japanese adults 65 years of age or older.
Topics: Adjuvants, Immunologic; Aged; Aged, 80 and over; alpha-Tocopherol; Asian People; Female; Humans; Influenza A Virus, H1N1 Subtype; Influenza Vaccines; Influenza, Human; Male; Oils; Squalene | 2012 |
Long-term immunogenicity of two doses of 2009 A/H1N1v vaccine with and without AS03(A) adjuvant in HIV-1-infected adults.
Topics: Adjuvants, Immunologic; alpha-Tocopherol; Antibodies, Neutralizing; Antibodies, Viral; Antibody Formation; Drug Combinations; Female; France; Hemagglutination Inhibition Tests; Hemagglutinins; HIV Infections; HIV-1; Humans; Influenza A Virus, H1N1 Subtype; Influenza Vaccines; Influenza, Human; Male; Polysorbates; Prospective Studies; Single-Blind Method; Smoking; Squalene; Time Factors | 2013 |
A randomized, controlled non-inferiority trial comparing A(H1N1)pmd09 vaccine antigen, with and without AS03 adjuvant system, co-administered or sequentially administered with an inactivated trivalent seasonal influenza vaccine.
Topics: Adjuvants, Immunologic; Adult; alpha-Tocopherol; Antibodies, Viral; Drug Combinations; Drug-Related Side Effects and Adverse Reactions; Female; Humans; Influenza Vaccines; Influenza, Human; Male; Polysorbates; Squalene; Vaccination; Young Adult | 2012 |
AS03-adjuvanted versus non-adjuvanted inactivated trivalent influenza vaccine against seasonal influenza in elderly people: a phase 3 randomised trial.
Topics: Adjuvants, Immunologic; Aged; Aged, 80 and over; alpha-Tocopherol; Drug Combinations; Female; Follow-Up Studies; Humans; Influenza A virus; Influenza A Virus, H1N1 Subtype; Influenza B virus; Influenza Vaccines; Influenza, Human; Male; Middle Aged; Polysorbates; Seasons; Squalene; Vaccines, Inactivated | 2013 |
Long-term persistence of humoral and cellular immune responses induced by an AS03A-adjuvanted H1N1 2009 influenza vaccine: an open-label, randomized study in adults aged 18-60 years and older.
Topics: Adjuvants, Immunologic; Adolescent; Adult; Aged; Aged, 80 and over; alpha-Tocopherol; Antibodies, Viral; B-Lymphocytes; CD4-Positive T-Lymphocytes; Drug Administration Schedule; Drug Combinations; Female; Hemagglutination Inhibition Tests; Humans; Immunity, Cellular; Immunologic Memory; Influenza A Virus, H1N1 Subtype; Influenza Vaccines; Influenza, Human; Male; Middle Aged; Polysorbates; Squalene; Vaccination; Young Adult | 2013 |
Long-term immunogenicity of an AS03-adjuvanted influenza A(H1N1)pdm09 vaccine in young and elderly adults: an observer-blind, randomized trial.
Topics: Adjuvants, Immunologic; Adolescent; Adult; alpha-Tocopherol; Antibodies, Viral; Antibody Formation; Drug Combinations; Hemagglutination Inhibition Tests; Humans; Influenza A Virus, H1N1 Subtype; Influenza Vaccines; Influenza, Human; Middle Aged; Polysorbates; Squalene; Vaccination; Young Adult | 2013 |
Safety, immunogenicity, and antibody persistence following an investigational Streptococcus pneumoniae and Haemophilus influenzae triple-protein vaccine in a phase 1 randomized controlled study in healthy adults.
Topics: Adjuvants, Immunologic; Adolescent; Adult; alpha-Tocopherol; Antibodies, Bacterial; CD4-Positive T-Lymphocytes; Drug Combinations; Drug-Related Side Effects and Adverse Reactions; Female; Haemophilus Vaccines; Humans; Male; Pneumococcal Vaccines; Polysorbates; Squalene; Vaccination; Vaccines, Combined; Vaccines, Subunit; Vaccines, Synthetic; Young Adult | 2014 |
An observer-blind, randomized, multi-center trial assessing long-term safety and immunogenicity of AS03-adjuvanted or unadjuvanted H1N1/2009 influenza vaccines in children 10-17 years of age.
Topics: Adjuvants, Immunologic; Adolescent; alpha-Tocopherol; Antibodies, Viral; Child; Drug Combinations; Estonia; Female; Hemagglutination Inhibition Tests; Humans; Immunity, Humoral; Immunization Schedule; Immunologic Memory; Influenza A Virus, H1N1 Subtype; Influenza Vaccines; Influenza, Human; Male; Polysorbates; Single-Blind Method; Slovakia; Squalene | 2014 |
Long-term booster schedules with AS03A-adjuvanted heterologous H5N1 vaccines induces rapid and broad immune responses in Asian adults.
Topics: Adult; alpha-Tocopherol; Animals; Antibodies, Neutralizing; Antibodies, Viral; Asian People; Cross Reactions; Drug Combinations; Female; Humans; Immunization Schedule; Immunization, Secondary; Influenza A Virus, H5N1 Subtype; Influenza Vaccines; Male; Middle Aged; Polysorbates; Squalene; Young Adult | 2014 |
High level antibody avidity is achieved in HIV-seropositive recipients of an inactivated split adjuvanted (AS03A) influenza vaccine.
Topics: Adult; alpha-Tocopherol; Antibodies, Viral; Antibody Affinity; Drug Combinations; Female; HIV; HIV Infections; HIV Seropositivity; Humans; Immunization, Secondary; Influenza A virus; Influenza Vaccines; Influenza, Human; Male; Mass Vaccination; Middle Aged; Polysorbates; Squalene; Treatment Outcome | 2014 |
AS03B-adjuvanted H5N1 influenza vaccine in children 6 months through 17 years of age: a phase 2/3 randomized, placebo-controlled, observer-blinded trial.
Topics: Adjuvants, Immunologic; Adolescent; alpha-Tocopherol; Antibodies, Viral; Child; Child, Preschool; Drug Combinations; Drug-Related Side Effects and Adverse Reactions; Female; Humans; Infant; Influenza A Virus, H5N1 Subtype; Influenza Vaccines; Influenza, Human; Male; Placebos; Polysorbates; Single-Blind Method; Squalene; Treatment Outcome; Vaccination; Vaccines, Inactivated | 2015 |
Long-term outcome of the humoral and cellular immune response of an H5N1 adjuvanted influenza vaccine in elderly persons: 2-year follow-up of a randomised open-label study.
Topics: Adjuvants, Immunologic; Age Factors; Aged; Aged, 80 and over; alpha-Tocopherol; Antibodies, Neutralizing; Antibodies, Viral; Belgium; Biomarkers; CD4-Positive T-Lymphocytes; Drug Combinations; Female; Follow-Up Studies; Hemagglutination Inhibition Tests; Humans; Immunity, Cellular; Immunity, Humoral; Immunization Schedule; Influenza A Virus, H5N1 Subtype; Influenza Vaccines; Influenza, Human; Male; Middle Aged; Polysorbates; Serologic Tests; Squalene; Time Factors; Treatment Outcome | 2014 |
A phase 1, open-label safety and immunogenicity study of an AS03-adjuvanted trivalent inactivated influenza vaccine in children aged 6 to 35 months.
Topics: Adjuvants, Immunologic; alpha-Tocopherol; Child, Preschool; Drug Combinations; Female; Fever; Hemagglutination Inhibition Tests; Humans; Incidence; Infant; Influenza Vaccines; Influenza, Human; Male; Polysorbates; Squalene; Vaccines, Inactivated | 2014 |
Immunogenicity of heterologous H5N1 influenza booster vaccination 6 or 18 months after primary vaccination in adults: a randomized controlled clinical trial.
Topics: Adjuvants, Immunologic; Adolescent; Adult; Aged; Aged, 80 and over; alpha-Tocopherol; Animals; Antibodies, Neutralizing; Antibodies, Viral; Drug Combinations; Female; Hemagglutination Inhibition Tests; Humans; Immunization, Secondary; Indonesia; Influenza A Virus, H5N1 Subtype; Influenza Vaccines; Influenza, Human; Leukocytes, Mononuclear; Male; Middle Aged; Neutralization Tests; Placebos; Polysorbates; Single-Blind Method; Squalene; Turkey; Young Adult | 2015 |
Safety of AS03-adjuvanted inactivated split virion A(H1N1)pdm09 and H5N1 influenza virus vaccines administered to adults: pooled analysis of 28 clinical trials.
Topics: Adjuvants, Immunologic; Adolescent; Adult; alpha-Tocopherol; Antibodies, Viral; Drug Combinations; Female; Humans; Influenza A Virus, H1N1 Subtype; Influenza A Virus, H5N1 Subtype; Influenza Vaccines; Influenza, Human; Male; Middle Aged; Polysorbates; Risk; Squalene; Vaccination; Young Adult | 2014 |
Phase II, randomized, open, controlled study of AS03-adjuvanted H5N1 pre-pandemic influenza vaccine in children aged 3 to 9 years: follow-up of safety and immunogenicity persistence at 24 months post-vaccination.
Topics: Adjuvants, Immunologic; alpha-Tocopherol; Antibodies, Viral; Child; Child, Preschool; Drug Combinations; Female; Follow-Up Studies; Hemagglutination Inhibition Tests; Hemagglutinin Glycoproteins, Influenza Virus; Humans; Immunity, Cellular; Infant; Influenza A Virus, H5N1 Subtype; Influenza Vaccines; Influenza, Human; Male; Polysorbates; Squalene; Vaccination | 2015 |
Safety and immunogenicity of an investigational 4-component Staphylococcus aureus vaccine with or without AS03B adjuvant: Results of a randomized phase I trial.
Topics: Adjuvants, Immunologic; Adolescent; Adult; alpha-Tocopherol; Antibodies, Bacterial; CD4-Positive T-Lymphocytes; CD8-Positive T-Lymphocytes; Drug Combinations; Drug-Related Side Effects and Adverse Reactions; Female; Healthy Volunteers; Humans; Male; Placebos; Polysorbates; Single-Blind Method; Squalene; Staphylococcal Infections; Staphylococcal Vaccines; Young Adult | 2015 |
Immunogenicity and Safety of an EB66 Cell-Culture-Derived Influenza A/Indonesia/5/2005(H5N1) AS03-Adjuvanted Vaccine: A Phase 1 Randomized Trial.
Topics: Adjuvants, Immunologic; Adolescent; Adult; alpha-Tocopherol; Animals; Antibodies, Viral; Cell Line; Drug Combinations; Ducks; Embryonic Stem Cells; Female; Humans; Influenza A Virus, H5N1 Subtype; Influenza Vaccines; Influenza, Human; Male; Middle Aged; Polysorbates; Single-Blind Method; Squalene; Young Adult | 2015 |
Immunogenicity and safety of an AS03-adjuvanted H5N1 pandemic influenza vaccine in Korean adults: a phase IV, randomized, open-label, controlled study.
Topics: Adjuvants, Immunologic; Adolescent; Adult; alpha-Tocopherol; Antibodies, Viral; Antibody Formation; Drug Combinations; Female; Hemagglutination Inhibition Tests; Humans; Immunization Schedule; Influenza A Virus, H5N1 Subtype; Influenza Vaccines; Influenza, Human; Male; Middle Aged; Pandemics; Polysorbates; Republic of Korea; Squalene; Vaccination; Vaccines, Inactivated; Young Adult | 2015 |
Single dose vaccination of the ASO3-adjuvanted A(H1N1)pdm09 monovalent vaccine in health care workers elicits homologous and cross-reactive cellular and humoral responses to H1N1 strains.
Topics: Adjuvants, Immunologic; Adult; alpha-Tocopherol; Antibodies, Viral; Cross Reactions; Drug Combinations; Female; Health Personnel; Hemagglutination Inhibition Tests; Humans; Immunity, Cellular; Immunity, Humoral; Immunization Schedule; Influenza A Virus, H1N1 Subtype; Influenza Vaccines; Influenza, Human; Interferon-gamma; Male; Middle Aged; Polysorbates; Squalene; Time Factors | 2015 |
Immunogenicity and Safety of a Trivalent Inactivated Influenza Vaccine in Children 6 Months to 17 Years of Age, Previously Vaccinated with an AS03-Adjuvanted A(H1N1)Pdm09 Vaccine: Two Open-label, Randomized Trials.
Topics: Adolescent; alpha-Tocopherol; Antibodies, Neutralizing; Antibodies, Viral; Child; Child, Preschool; Drug Combinations; Female; Hemagglutination Inhibition Tests; Humans; Infant; Influenza Vaccines; Influenza, Human; Male; Polysorbates; Squalene; Treatment Outcome; Vaccination | 2015 |
Safety and persistence of the humoral and cellular immune responses induced by 2 doses of an AS03-adjuvanted A(H1N1)pdm09 pandemic influenza vaccine administered to infants, children and adolescents: Two open, uncontrolled studies.
Topics: Adjuvants, Immunologic; Adolescent; alpha-Tocopherol; Antibodies, Neutralizing; Antibodies, Viral; Child; Child, Preschool; Drug Combinations; Female; Humans; Immunity, Cellular; Infant; Influenza A Virus, H1N1 Subtype; Influenza Vaccines; Influenza, Human; Male; Polysorbates; Squalene; Time Factors; Treatment Outcome | 2015 |
Effect of Varying Doses of a Monovalent H7N9 Influenza Vaccine With and Without AS03 and MF59 Adjuvants on Immune Response: A Randomized Clinical Trial.
Topics: Adjuvants, Immunologic; Adult; Age Factors; alpha-Tocopherol; Antibodies, Viral; Double-Blind Method; Drug Combinations; Female; Hemagglutination Inhibition Tests; Hemagglutination, Viral; Humans; Influenza A Virus, H7N9 Subtype; Influenza Vaccines; Influenza, Human; Male; Middle Aged; Polysorbates; Squalene | 2015 |
A clinical phase I study of an EB66 cell-derived H5N1 pandemic vaccine adjuvanted with AS03.
Topics: Adjuvants, Immunologic; Adult; alpha-Tocopherol; Animals; Antibodies, Neutralizing; Antibodies, Viral; Cell Line; Cross Reactions; Drug Combinations; Ducks; Hemagglutination Inhibition Tests; Humans; Immunization Schedule; Influenza A Virus, H5N1 Subtype; Influenza Vaccines; Influenza, Human; Injections, Intramuscular; Male; Orthomyxoviridae Infections; Pandemics; Polysorbates; Squalene; Young Adult | 2015 |
Assessment of Prime-boost Vaccination Using an AS03B-adjuvanted Influenza A (H5N1) Vaccine: A Randomized Trial in Children of Three to Less Than Eighteen Years of Age.
Topics: Adjuvants, Immunologic; Adolescent; alpha-Tocopherol; Antibodies, Viral; Child; Child, Preschool; Drug Combinations; Female; Hemagglutination Inhibition Tests; Humans; Immunization; Influenza A Virus, H5N1 Subtype; Influenza Vaccines; Male; Neutralization Tests; Polysorbates; Squalene; Treatment Outcome | 2016 |
Persistence of Antibody to Influenza A/H5N1 Vaccine Virus: Impact of AS03 Adjuvant.
Topics: Adjuvants, Immunologic; Adolescent; Adult; alpha-Tocopherol; Antibodies, Viral; Double-Blind Method; Drug Combinations; Female; Humans; Influenza A Virus, H5N1 Subtype; Influenza Vaccines; Influenza, Human; Male; Middle Aged; Polysorbates; Squalene; Time Factors; Vaccination; Young Adult | 2016 |
Immunogenicity and Safety of an AS03-Adjuvanted H7N9 Pandemic Influenza Vaccine in a Randomized Trial in Healthy Adults.
Topics: Adjuvants, Immunologic; Adolescent; Adult; alpha-Tocopherol; Antibodies, Viral; Drug Combinations; Drug-Related Side Effects and Adverse Reactions; Female; Healthy Volunteers; Humans; Immunization Schedule; Influenza A Virus, H7N9 Subtype; Influenza Vaccines; Influenza, Human; Male; Middle Aged; Placebos; Polysorbates; Single-Blind Method; Squalene; Vaccines, Inactivated; Young Adult | 2016 |
Immunogenicity of AS03-adjuvanted and non-adjuvanted trivalent inactivated influenza vaccines in elderly adults: A Phase 3, randomized trial and post-hoc correlate of protection analysis.
Topics: Aged; Aged, 80 and over; alpha-Tocopherol; Antibodies, Viral; Drug Combinations; Female; Hemagglutination Inhibition Tests; Humans; Influenza A Virus, H3N2 Subtype; Influenza Vaccines; Influenza, Human; Male; Polysorbates; Single-Blind Method; Squalene; Treatment Outcome; Vaccines, Inactivated | 2016 |
Investigating the effect of AS03 adjuvant on the plasma cell repertoire following pH1N1 influenza vaccination.
Topics: Adjuvants, Immunologic; Adult; alpha-Tocopherol; Antibodies, Viral; B-Lymphocytes; Double-Blind Method; Drug Combinations; Humans; Immunization Schedule; Influenza A Virus, H1N1 Subtype; Influenza Vaccines; Influenza, Human; Polysorbates; Squalene; Vaccination | 2016 |
Immunogenicity and safety of an AS03-adjuvanted H7N1 vaccine in healthy adults: A phase I/II, observer-blind, randomized, controlled trial.
Topics: Adaptive Immunity; Adjuvants, Immunologic; Adult; alpha-Tocopherol; Animals; Antibodies, Viral; Canada; Drug Combinations; Drug-Related Side Effects and Adverse Reactions; Female; Healthy Volunteers; Hemagglutination Inhibition Tests; Humans; Influenza A Virus, H7N1 Subtype; Influenza Vaccines; Influenza, Human; Male; Middle Aged; Neutralization Tests; Placebos; Polysorbates; Single-Blind Method; Squalene; United States; Vaccines, Inactivated; Young Adult | 2017 |
Immunogenicity and safety of an AS03-adjuvanted H7N1 vaccine in adults 65years of age and older: A phase II, observer-blind, randomized, controlled trial.
Topics: Adult; Aged; Aged, 80 and over; alpha-Tocopherol; Animals; Antibodies, Neutralizing; Antibodies, Viral; Drug Combinations; Drug-Related Side Effects and Adverse Reactions; Female; Healthy Volunteers; Hemagglutination Inhibition Tests; Humans; Influenza A Virus, H7N1 Subtype; Influenza Vaccines; Male; Neutralization Tests; Placebos; Polysorbates; Single-Blind Method; Squalene; Vaccines, Inactivated | 2017 |
Evaluation of a primary course of H9N2 vaccine with or without AS03 adjuvant in adults: A phase I/II randomized trial.
Topics: Adjuvants, Immunologic; Adult; alpha-Tocopherol; Antibodies, Viral; Drug Combinations; Female; Hemagglutination Inhibition Tests; Humans; Immunogenicity, Vaccine; Immunologic Memory; Influenza A Virus, H9N2 Subtype; Influenza Vaccines; Influenza, Human; Male; Middle Aged; Neutralization Tests; Pandemics; Polysorbates; Squalene; Vaccination; Young Adult | 2017 |
AS03-Adjuvanted H5N1 Avian Influenza Vaccine Modulates Early Innate Immune Signatures in Human Peripheral Blood Mononuclear Cells.
Topics: Adaptive Immunity; Adjuvants, Immunologic; Adult; alpha-Tocopherol; Double-Blind Method; Drug Combinations; Gene Expression Profiling; Humans; Immunity, Innate; Influenza A Virus, H5N1 Subtype; Influenza Vaccines; Influenza, Human; Leukocytes; Polysorbates; Signal Transduction; Squalene; Young Adult | 2019 |
Clinical phase II and III studies of an AS03-adjuvanted H5N1 influenza vaccine produced in an EB66
Topics: Adult; alpha-Tocopherol; Antibodies, Viral; Cell Culture Techniques; Double-Blind Method; Drug Combinations; Female; Humans; Immunogenicity, Vaccine; Influenza A Virus, H5N1 Subtype; Influenza Vaccines; Influenza, Human; Injections, Intramuscular; Male; Middle Aged; Polysorbates; Random Allocation; Squalene; Vaccination; Young Adult | 2020 |
The single-cell epigenomic and transcriptional landscape of immunity to influenza vaccination.
Topics: Adolescent; Adult; alpha-Tocopherol; Anti-Bacterial Agents; Antigens, CD34; Antiviral Agents; Cellular Reprogramming; Chromatin; Cytokines; Drug Combinations; Epigenomics; Female; Gene Expression Regulation; Histones; Humans; Immunity; Immunity, Innate; Influenza A Virus, H5N1 Subtype; Influenza Vaccines; Interferon Type I; Male; Myeloid Cells; Polysorbates; Single-Cell Analysis; Squalene; Toll-Like Receptors; Transcription Factor AP-1; Transcription, Genetic; Transcriptome; Vaccination; Young Adult | 2021 |
Safety and immunogenicity of monovalent H7N9 influenza vaccine with AS03 adjuvant given sequentially or simultaneously with a seasonal influenza vaccine: A randomized clinical trial.
Topics: Adjuvants, Immunologic; Adult; alpha-Tocopherol; Animals; Antibodies, Viral; Drug Combinations; Hemagglutination Inhibition Tests; Humans; Immunogenicity, Vaccine; Influenza A Virus, H7N9 Subtype; Influenza in Birds; Influenza Vaccines; Influenza, Human; Polysorbates; Seasons; Squalene; Vaccines, Inactivated | 2022 |
77 other study(ies) available for d-alpha tocopherol and squalene
| Article | Year |
|---|---|
Freund's adjuvants: relationship of arthritogenicity and adjuvanticity in rats to vehicle composition.
Topics: Alkanes; Animals; Arthritis; Body Weight; Corynebacterium; Encephalomyelitis, Autoimmune, Experimental; Fatty Acids; Freund's Adjuvant; Hydrocarbons; Male; Mycobacterium tuberculosis; Nocardia asteroides; Oils; Oxygen; Pharmaceutical Vehicles; Rats; Squalene; Structure-Activity Relationship; Triglycerides; Vaccines, Attenuated; Vitamin A; Vitamin E; Vitamin K | 1974 |
Quantitative changes in some unsaponifiable components of soya bean oil due to refining.
Topics: Food-Processing Industry; Glycine max; Hydrogen-Ion Concentration; Oils; Phytosterols; Sitosterols; Squalene; Stigmasterol; Vitamin E | 1974 |
Biosynthesis of phytoquinones. Stereospecific biosynthesis of the polyprenyl side chains of terpenoid quinones and chromanols in maize shoots.
Topics: Alkenes; Carbon Isotopes; Carotenoids; Chemical Phenomena; Chemistry, Physical; Mevalonic Acid; Plants; Quinones; Squalene; Sterols; Tritium; Ubiquinone; Vitamin E; Zea mays | 1968 |
Biosynthesis of phytoquinones. Incorporation of L-[Me-14C,3H]methionine into terpenoid quinones and chromanols in maize shoots.
Topics: Carbon Isotopes; Carotenoids; Chloroplasts; Lipids; Methionine; Methylation; Naphthoquinones; Plants; Quinones; Squalene; Sterols; Terpenes; Tritium; Ubiquinone; Vitamin E; Vitamin K; Zea mays | 1968 |
The possible role of squalene and its peroxide of the sebum in the occurrence of sunburn and protection from the damage caused by U.V. irradiation.
Topics: Animals; Guinea Pigs; Hydrogen-Ion Concentration; Lipid Peroxides; Male; Oxygen Consumption; Sebum; Skin; Squalene; Sunburn; Ultraviolet Rays; Vitamin E | 1984 |
Lipid peroxidation during chronic inflammation induced in rats by Freund's adjuvant: effect of vitamin E as measured by expired pentane.
Topics: Animals; Foot; Freund's Adjuvant; Inflammation; Lipid Peroxides; Male; Pentanes; Rats; Rats, Inbred Strains; Squalene; Vitamin E; Vitamin E Deficiency | 1982 |
Inhibition of rat liver sterol formation by isoprenoid and conjugated ene compounds.
Topics: Acyclic Monoterpenes; Animals; Cytosol; Dolichols; In Vitro Techniques; Liver; Mevalonic Acid; Microsomes, Liver; Monoterpenes; Phytol; Rats; Squalene; Sterols; Terpenes; Ubiquinone; Vitamin E | 1982 |
Synergistic effects of alpha-tocopherol, beta-sitosterol and squalene on antioxidant activity assayed by crocin bleaching method.
Topics: Algorithms; Antioxidants; Carotenoids; Drug Synergism; Hypolipidemic Agents; Kinetics; Sitosterols; Squalene; Vitamin E | 2000 |
Acute effect of dietary stanyl ester dose on post-absorptive alpha-tocopherol, beta-carotene, retinol and retinyl palmitate concentrations.
Topics: Analysis of Variance; Area Under Curve; beta Carotene; Cholesterol; Chylomicrons; Dose-Response Relationship, Drug; Esters; Humans; Intestinal Absorption; Male; Middle Aged; Palmitates; Phytosterols; Postprandial Period; Sitosterols; Squalene; Statistics, Nonparametric; Triglycerides; Vitamin A; Vitamin E | 2001 |
Determination of aliphatic alcohols, squalene, alpha-tocopherol and sterols in olive oils: direct method involving gas chromatography of the unsaponifiable fraction following silylation.
Topics: Alcohols; Chromatography, Gas; Olive Oil; Plant Oils; Sensitivity and Specificity; Squalene; Sterols; Vitamin E | 2001 |
Stability of virgin olive oil. 1. Autoxidation studies.
Topics: alpha-Tocopherol; Carotenoids; Chlorophyll; Chromatography, High Pressure Liquid; Colorimetry; Drug Stability; Fatty Acids; Food Preservation; Olive Oil; Oxidation-Reduction; Peroxides; Phenols; Pheophytins; Plant Oils; Squalene | 2002 |
Stability of virgin olive oil. 2. Photo-oxidation studies.
Topics: alpha-Tocopherol; Chlorophyll; Chromatography, High Pressure Liquid; Drug Stability; Lipids; Olive Oil; Oxidation-Reduction; Oxygen; Phenols; Pheophytins; Photochemistry; Plant Oils; Singlet Oxygen; Squalene | 2002 |
Lipophilic antioxidants in human sebum and aging.
Topics: Administration, Topical; Adolescent; Adult; Aged; Aged, 80 and over; Antioxidants; Biological Availability; Child; Cholesterol; Coenzymes; Cytoprotection; Fatty Acids; Female; Humans; Lipid Metabolism; Male; Middle Aged; Sebum; Skin; Skin Aging; Squalene; Triglycerides; Ubiquinone; Ultraviolet Rays; Vitamin A; Vitamin E | 2002 |
Rate of degradation of alpha-tocopherol, squalene, phenolics, and polyunsaturated fatty acids in olive oil during different storage conditions.
Topics: alpha-Tocopherol; Chromatography, High Pressure Liquid; Drug Stability; Fatty Acids, Unsaturated; Food Preservation; Gas Chromatography-Mass Spectrometry; Italy; Kinetics; Lipid Peroxidation; Mass Spectrometry; Olive Oil; Oxidation-Reduction; Peroxides; Phenols; Photochemistry; Plant Oils; Squalene | 2002 |
3,4-Dihydroxymandelic acid, a noradrenalin metabolite with powerful antioxidative potential.
Topics: alpha-Tocopherol; Antioxidants; Ascorbic Acid; Biphenyl Compounds; Butylated Hydroxytoluene; Chemical Phenomena; Chemistry, Physical; Drug Synergism; Fibroblasts; Free Radical Scavengers; Humans; Hydrogen Peroxide; Lipid Peroxidation; Mandelic Acids; Oxidative Stress; Picrates; Soybean Oil; Squalene; Superoxides; Tocopherols | 2002 |
INFLUENCE OF DIETARY PHYTOL, ISOPHYTOL, AND SQUALENE ON THE TOCOPHEROL CONTENT OF LIVER TISSUE.
Topics: Animals; Blood; Diet; Liver; Phytol; Poultry; Research; Squalene; Terpenes; Tocopherols; Vitamin E; Vitamin E Deficiency | 1964 |
Antioxidant effect of phenolic compounds, alpha-tocopherol, and other minor components in virgin olive oil.
Topics: alpha-Tocopherol; Antioxidants; Drug Stability; Fatty Acids; Flavonoids; Hydrogen-Ion Concentration; Kinetics; Oleic Acid; Olive Oil; Oxidation-Reduction; Phenols; Plant Oils; Squalene | 2003 |
The combined use of oral and topical lipophilic antioxidants increases their levels both in sebum and stratum corneum.
Topics: Administration, Oral; Administration, Topical; Adult; alpha-Tocopherol; Antioxidants; Coenzymes; Drug Therapy, Combination; Epidermis; Female; Humans; Kinetics; Oxidation-Reduction; Sebum; Selenium; Squalene; Tocopherols; Ubiquinone; Vitamin E | 2003 |
Application of supercritical fluid chromatography in the quantitative analysis of minor components (carotenes, vitamin E, sterols, and squalene) from palm oil.
Topics: Carotenoids; Chromatography, Gas; Chromatography, High Pressure Liquid; Chromatography, Supercritical Fluid; Palm Oil; Phytosterols; Plant Oils; Squalene; Time Factors; Vitamin E | 2005 |
Attenuation of cyclophosphamide induced toxicity by squalene in experimental rats.
Topics: Administration, Oral; Animals; Antioxidants; Ascorbic Acid; Catalase; Ceruloplasmin; Cyclophosphamide; Dose-Response Relationship, Drug; Drug Interactions; Erythrocytes; Glutathione; Glutathione Peroxidase; Glutathione Reductase; Glutathione Transferase; Heart; Lipid Peroxidation; Rats; Rats, Wistar; Squalene; Superoxide Dismutase; Thiobarbituric Acid Reactive Substances; Vitamin E | 2006 |
Distribution of Vitamin E, squalene, epicatechin, and rutin in common buckwheat plants (Fagopyrum esculentum Moench).
Topics: alpha-Tocopherol; Catechin; Chromatography, High Pressure Liquid; Fagopyrum; Gas Chromatography-Mass Spectrometry; Plant Leaves; Rutin; Squalene | 2006 |
Antioxidant activities of essential oil mixtures toward skin lipid squalene oxidized by UV irradiation.
Topics: alpha-Tocopherol; Antioxidants; Butylated Hydroxytoluene; Chromatography, Gas; Clove Oil; Dose-Response Relationship, Drug; Lipid Peroxidation; Malondialdehyde; Oils, Volatile; Oxidation-Reduction; Petroselinum; Rosa; Skin; Squalene; Thymus Plant; Ultraviolet Rays | 2007 |
Chemical characterization and DNA tracking of Sardinian botargo by Mugil cephalus from different geographical origins.
Topics: Animals; Antioxidants; Cholesterol; DNA; Eggs; Fatty Acids; Fish Products; Fishes; Italy; Squalene; Vitamin E | 2008 |
Human synthetic sebum formulation and stability under conditions of use and storage.
Topics: Drug Stability; Drug Storage; Humans; Oleic Acid; Sebum; Squalene; Surface Properties; Triolein; Vitamin E; Waxes | 2009 |
The potential of Pleurotus-treated olive mill solid waste as cattle feed.
Topics: alpha-Tocopherol; Animal Feed; Animals; Biodegradation, Environmental; Cattle; Fatty Acids; gamma-Tocopherol; Industrial Waste; Oils; Olea; Pleurotus; Refuse Disposal; Sitosterols; Solubility; Squalene; Time Factors | 2009 |
gamma-Tocotrienol reduces squalene hydroperoxide-induced inflammatory responses in HaCaT keratinocytes.
Topics: Cells, Cultured; Chromans; Cyclooxygenase 2; Humans; Inflammation Mediators; Keratinocytes; Reactive Oxygen Species; RNA, Messenger; Skin; Squalene; Vitamin E | 2010 |
An adjuvanted pandemic influenza H1N1 vaccine provides early and long term protection in health care workers.
Topics: Adult; Aged; alpha-Tocopherol; Antibodies, Viral; Drug Combinations; Female; Health Personnel; Hemagglutination Inhibition Tests; Humans; Influenza A Virus, H1N1 Subtype; Influenza Vaccines; Influenza, Human; Male; Middle Aged; Polysorbates; Squalene; Time Factors; Vaccines, Subunit | 2010 |
Immunogenicity of pandemic (H1N1) 2009 vaccine in children with cancer in the United Kingdom.
Topics: Adjuvants, Immunologic; Adolescent; alpha-Tocopherol; Antibodies, Viral; Child; Child, Preschool; Drug Combinations; Female; Hemagglutination Inhibition Tests; Humans; Immunization, Secondary; Infant; Influenza A Virus, H1N1 Subtype; Influenza Vaccines; Male; Neoplasms; Polysorbates; Squalene; United Kingdom; Vaccination | 2010 |
Age-specific effectiveness of an oil-in-water adjuvanted pandemic (H1N1) 2009 vaccine against confirmed infection in high risk groups in England.
Topics: Adjuvants, Immunologic; Adolescent; Adult; Age Factors; Aged; Aged, 80 and over; alpha-Tocopherol; Child; Child, Preschool; Drug Combinations; Emulsions; England; Female; Humans; Infant; Infant, Newborn; Influenza A Virus, H1N1 Subtype; Influenza Vaccines; Influenza, Human; Male; Middle Aged; Polysorbates; Squalene; Young Adult | 2011 |
Delayed focal lipoatrophy after AS03-adjuvanted influenza A (H1N1) 2009 vaccine.
Topics: Adult; alpha-Tocopherol; Drug Combinations; Female; Humans; Influenza A Virus, H1N1 Subtype; Influenza Vaccines; Injections, Intramuscular; Lipodystrophy; Polysorbates; Skin Diseases; Squalene; Subcutaneous Tissue | 2011 |
Adjuvant System AS03 containing α-tocopherol modulates innate immune response and leads to improved adaptive immunity.
Topics: Adaptive Immunity; Adjuvants, Immunologic; alpha-Tocopherol; Animals; Antibodies, Viral; Cell Line; Cytokines; Drug Combinations; Emulsions; Female; Granulocytes; Humans; Immunity, Innate; Influenza Vaccines; Lymphocytes; Mice; Mice, Inbred C57BL; Monocytes; Muscles; Polysorbates; Squalene; Tocopherols | 2011 |
Humoral response to the influenza A H1N1/09 monovalent AS03-adjuvanted vaccine in immunocompromised patients.
Topics: Adjuvants, Immunologic; Adult; alpha-Tocopherol; Antibodies, Neutralizing; Antibodies, Viral; Drug Combinations; Female; Hemagglutination Inhibition Tests; HIV Infections; Humans; Immunization, Secondary; Immunocompromised Host; Influenza A Virus, H1N1 Subtype; Influenza Vaccines; Male; Middle Aged; Neutralization Tests; Organ Transplantation; Polysorbates; Squalene; Vaccination | 2011 |
The immunogenicity of a novel A (H1N1) vaccine in HIV-infected children.
Topics: Adjuvants, Immunologic; Adolescent; alpha-Tocopherol; Antibodies, Viral; CD4 Lymphocyte Count; Child; Child, Preschool; Drug Combinations; Female; Hemagglutination Inhibition Tests; HIV Infections; HIV-1; Humans; Immunization, Secondary; Influenza Vaccines; Male; Polysorbates; Squalene; United Kingdom; Vaccination; Viral Load | 2011 |
Influenza A/H1N1 vaccine in patients treated by kidney transplant or dialysis: a cohort study.
Topics: Adult; Aged; alpha-Tocopherol; Analysis of Variance; Antibodies, Neutralizing; Antibodies, Viral; Belgium; Case-Control Studies; Chi-Square Distribution; Cohort Studies; Drug Combinations; Female; Histocompatibility Antigens Class I; Histocompatibility Antigens Class II; Humans; Immunosuppressive Agents; Influenza A Virus, H1N1 Subtype; Influenza Vaccines; Influenza, Human; Kidney Failure, Chronic; Kidney Transplantation; Male; Middle Aged; Odds Ratio; Polysorbates; Regression Analysis; Renal Dialysis; Squalene; Time Factors; Treatment Outcome | 2011 |
Strong serological responses and HIV RNA increase following AS03-adjuvanted pandemic immunization in HIV-infected patients.
Topics: Adult; alpha-Tocopherol; Antibodies, Viral; Drug Combinations; Female; Hemagglutination Inhibition Tests; HIV Infections; HIV-1; Humans; Influenza Vaccines; Male; Middle Aged; Polysorbates; Prospective Studies; RNA, Viral; Squalene; Viral Load | 2012 |
Usefulness of health registries when estimating vaccine effectiveness during the influenza A(H1N1)pdm09 pandemic in Norway.
Topics: Adjuvants, Immunologic; Adolescent; Adult; Aged; Aged, 80 and over; alpha-Tocopherol; Child; Child, Preschool; Cohort Studies; Drug Combinations; Female; Humans; Infant; Infant, Newborn; Influenza A Virus, H1N1 Subtype; Influenza Vaccines; Influenza, Human; Male; Middle Aged; Norway; Polysorbates; Registries; Retrospective Studies; Squalene; Treatment Outcome; Young Adult | 2012 |
Immune response after one or two doses of pandemic influenza A (H1N1) monovalent, AS03-adjuvanted vaccine in HIV infected adults.
Topics: Adult; Aged; Aged, 80 and over; alpha-Tocopherol; Antibodies, Viral; Drug Combinations; Female; HIV Infections; Humans; Influenza A Virus, H1N1 Subtype; Influenza Vaccines; Influenza, Human; Male; Middle Aged; Polysorbates; Squalene | 2012 |
Multi-centre observational study of transplacental transmission of influenza antibodies following vaccination with AS03(A)-adjuvanted H1N1 2009 vaccine.
Topics: Adult; alpha-Tocopherol; Antibodies, Viral; Drug Combinations; Female; Fetus; Hemagglutination Inhibition Tests; Humans; Immunity, Maternally-Acquired; Infant; Influenza A Virus, H1N1 Subtype; Influenza Vaccines; Influenza, Human; Mass Vaccination; Pandemics; Polysorbates; Pregnancy; Squalene; United Kingdom | 2013 |
AS03-adjuvanted influenza vaccine in elderly people.
Topics: Adjuvants, Immunologic; alpha-Tocopherol; Drug Combinations; Female; Humans; Influenza A virus; Influenza B virus; Influenza Vaccines; Influenza, Human; Male; Polysorbates; Squalene | 2013 |
[Catastrophic consequences of Pandemrix swine flu vaccine containing squalene].
Topics: Adjuvants, Immunologic; alpha-Tocopherol; Drug Combinations; Humans; Influenza A Virus, H1N1 Subtype; Influenza Vaccines; Influenza, Human; Narcolepsy; Polysorbates; Squalene | 2013 |
Increased risk of anaphylaxis following administration of 2009 AS03-adjuvanted monovalent pandemic A/H1N1 (H1N1pdm09) vaccine.
Topics: Adjuvants, Immunologic; Adolescent; Adult; Aged; Aged, 80 and over; alpha-Tocopherol; Anaphylaxis; Canada; Child; Child, Preschool; Drug Combinations; Drug-Related Side Effects and Adverse Reactions; Female; Humans; Incidence; Influenza A Virus, H1N1 Subtype; Influenza Vaccines; Influenza, Human; Male; Middle Aged; Polysorbates; Quebec; Risk Assessment; Squalene; Young Adult | 2013 |
Administration of AS03B-adjuvanted A(H1N1)pdm09 vaccine in children aged <3 years enhances antibody response to H3 and B viruses following a single dose of trivalent vaccine one year later.
Topics: Adjuvants, Immunologic; alpha-Tocopherol; Antibodies, Viral; Child; Child, Preschool; Cross Reactions; Drug Combinations; Female; Follow-Up Studies; Hemagglutination Inhibition Tests; Humans; Infant; Influenza A Virus, H1N1 Subtype; Influenza A Virus, H3N2 Subtype; Influenza B virus; Influenza Vaccines; Male; Polysorbates; Squalene; Vaccination | 2014 |
Lipid composition of fingermark residue and donor classification using GC/MS.
Topics: Adult; Alkanes; Cluster Analysis; Dermatoglyphics; Female; Forensic Sciences; Gas Chromatography-Mass Spectrometry; Humans; Lipids; Male; Middle Aged; Sebum; Squalene; Vitamin E | 2014 |
Durability of protective antibody titres is not enhanced by a two-dose schedule of an ASO3-adjuvanted pandemic H1N1 influenza vaccine in adult HIV-1-infected patients.
Topics: Adjuvants, Immunologic; Adult; Aged; alpha-Tocopherol; Antibodies, Viral; Drug Combinations; Female; HIV Infections; HIV-1; Humans; Immunization Schedule; Influenza A Virus, H1N1 Subtype; Influenza Vaccines; Influenza, Human; Male; Middle Aged; Polysorbates; Squalene; Vaccination | 2014 |
Hepatitis C virus hypervariable region 1 variants presented on hepatitis B virus capsid-like particles induce cross-neutralizing antibodies.
Topics: alpha-Tocopherol; Animals; Antibodies, Neutralizing; Antibodies, Viral; Antigen Presentation; Antigens, Viral; Capsid Proteins; Cross Protection; Drug Combinations; Escherichia coli; Female; Gene Expression; Hepacivirus; Hepatitis B virus; Hepatitis C; Humans; Immunity, Humoral; Injections, Intramuscular; Injections, Subcutaneous; Mice; Mice, Inbred C57BL; Polysorbates; Recombinant Proteins; Squalene; Viral Hepatitis Vaccines; Viral Proteins | 2014 |
Delta-tocotrienol induces apoptotic cell death via depletion of intracellular squalene in ED40515 cells.
Topics: Apoptosis; bcl-2-Associated X Protein; bcl-X Protein; Caspase 3; Caspase 6; Caspase 7; Caspase 9; Cell Line, Tumor; Cell Proliferation; DNA Fragmentation; Down-Regulation; Farnesyl-Diphosphate Farnesyltransferase; Humans; Squalene; Transcription Factor RelA; Vitamin E; X-Linked Inhibitor of Apoptosis Protein | 2014 |
Risk of narcolepsy associated with inactivated adjuvanted (AS03) A/H1N1 (2009) pandemic influenza vaccine in Quebec.
Topics: Adjuvants, Immunologic; Adolescent; Adult; alpha-Tocopherol; Case-Control Studies; Child; Drug Combinations; Female; Humans; Influenza A Virus, H1N1 Subtype; Influenza Vaccines; Influenza, Human; Male; Middle Aged; Narcolepsy; Polysorbates; Quebec; Retrospective Studies; Squalene; Vaccination; Young Adult | 2014 |
Chemical characterization and antioxidant activity of Amazonian (Ecuador) Caryodendron orinocense Karst. and Bactris gasipaes Kunth seed oils.
Topics: Antioxidants; Arecaceae; Cholesterol; Chromatography, High Pressure Liquid; Euphorbiaceae; Fatty Acids; Free Radical Scavengers; Gas Chromatography-Mass Spectrometry; Lauric Acids; Linoleic Acid; Magnetic Resonance Spectroscopy; Myristic Acid; Nuts; Phytosterols; Plant Oils; Seeds; Sitosterols; Squalene; Stigmasterol; Vitamin E | 2014 |
A first-generation physiologically based pharmacokinetic (PBPK) model of alpha-tocopherol in human influenza vaccine adjuvant.
Topics: Adipose Tissue; Adjuvants, Immunologic; Adult; alpha-Tocopherol; Animals; Chemistry, Pharmaceutical; Computer Simulation; Drug Combinations; Emulsions; Humans; Infant; Influenza Vaccines; Injections, Intramuscular; Lymphatic System; Models, Animal; Models, Biological; Polysorbates; Risk Assessment; Sheep; Squalene | 2015 |
Impact of Adjuvants on the Immunogenicity and Efficacy of Split-Virion H7N9 Vaccine in Ferrets.
Topics: Adjuvants, Immunologic; alpha-Tocopherol; Animals; Antibodies, Viral; Cross Reactions; Dose-Response Relationship, Immunologic; Drug Combinations; Ferrets; Influenza A Virus, H7N9 Subtype; Influenza Vaccines; Male; Polysorbates; Specific Pathogen-Free Organisms; Squalene | 2015 |
Non-clinical safety and biodistribution of AS03-adjuvanted inactivated pandemic influenza vaccines.
Topics: alpha-Tocopherol; Animals; Carbon Radioisotopes; Disease Outbreaks; Drug Combinations; Drug Evaluation, Preclinical; Female; Humans; Influenza A Virus, H5N1 Subtype; Influenza Vaccines; Injections, Intramuscular; Male; Mice, Inbred C57BL; Orthomyxoviridae Infections; Polysorbates; Rabbits; Squalene; Tissue Distribution; Tritium | 2015 |
Chemical characterization and assessment of antioxidant potentiality of Streptocaulon sylvestre Wight, an endangered plant of sub-Himalayan plains of West Bengal and Sikkim.
Topics: Animals; Antioxidants; Apocynaceae; Chromatography, High Pressure Liquid; Coumaric Acids; Endangered Species; Flavonoids; Gas Chromatography-Mass Spectrometry; Hydrolyzable Tannins; Iron Chelating Agents; Lipid Peroxidation; Mice; Phenols; Plant Extracts; Propionates; Sikkim; Sitosterols; Squalene; Vitamin E | 2015 |
AS03-adjuvanted H7N1 detergent-split virion vaccine is highly immunogenic in unprimed mice and induces cross-reactive antibodies to emerged H7N9 and additional H7 subtypes.
Topics: alpha-Tocopherol; Animals; Antibodies, Neutralizing; Antibodies, Viral; Cross Reactions; Drug Combinations; Female; Hemagglutination Inhibition Tests; Influenza A Virus, H7N1 Subtype; Influenza A Virus, H7N9 Subtype; Influenza Vaccines; Mice, Inbred C57BL; Neutralization Tests; Polysorbates; Squalene; Vaccines, Inactivated | 2015 |
Paresthesia and sensory disturbances associated with 2009 pandemic vaccine receipt: Clinical features and risk factors.
Topics: Adolescent; Adult; Aged; alpha-Tocopherol; Case-Control Studies; Child; Drug Combinations; Europe; Female; Humans; Influenza A Virus, H1N1 Subtype; Influenza Vaccines; Influenza, Human; Male; Middle Aged; Paresthesia; Polysorbates; Quebec; Risk Factors; Squalene; Young Adult | 2015 |
Perinatal survival and health after maternal influenza A(H1N1)pdm09 vaccination: A cohort study of pregnancies stratified by trimester of vaccination.
Topics: Adolescent; Adult; alpha-Tocopherol; Drug Combinations; Female; Finland; Humans; Immunization Schedule; Infant Health; Infant, Low Birth Weight; Infant, Newborn; Influenza A Virus, H1N1 Subtype; Influenza Vaccines; Polysorbates; Pregnancy; Pregnancy Complications; Premature Birth; Retrospective Studies; Squalene; Stillbirth; Survival Analysis; Young Adult | 2015 |
Comparison of AS03 and Alum on immune responses elicited by A/H3N2 split influenza vaccine in young, mature and aged BALB/c mice.
Topics: Adjuvants, Immunologic; Age Factors; alpha-Tocopherol; Alum Compounds; Animals; Antibodies, Viral; Cytokines; Dose-Response Relationship, Immunologic; Drug Combinations; Female; Hemagglutination Inhibition Tests; Immunity, Cellular; Immunity, Humoral; Influenza A Virus, H3N2 Subtype; Influenza Vaccines; Mice, Inbred BALB C; Neutralization Tests; Orthomyxoviridae Infections; Polysorbates; Spleen; Squalene | 2016 |
Extrapolating theoretical efficacy of inactivated influenza A/H5N1 virus vaccine from human immunogenicity studies.
Topics: Adjuvants, Immunologic; alpha-Tocopherol; Antibodies, Viral; Clinical Trials, Phase I as Topic; Clinical Trials, Phase II as Topic; Dose-Response Relationship, Immunologic; Drug Combinations; Hemagglutination Inhibition Tests; Humans; Immunogenicity, Vaccine; Influenza A Virus, H5N1 Subtype; Influenza Vaccines; Influenza, Human; Polysorbates; Randomized Controlled Trials as Topic; Squalene; Vaccines, Inactivated | 2016 |
Obesity Outweighs Protection Conferred by Adjuvanted Influenza Vaccination.
Topics: Adjuvants, Immunologic; alpha-Tocopherol; Alum Compounds; Animals; Antibodies, Neutralizing; Antibodies, Viral; Disease Models, Animal; Drug Combinations; Hemagglutinin Glycoproteins, Influenza Virus; Humans; Influenza A Virus, H7N9 Subtype; Influenza Vaccines; Influenza, Human; Mice, Inbred C57BL; Mice, Obese; Neuraminidase; Obesity; Polysorbates; Respiratory System; Squalene; Survival Analysis; Treatment Outcome; Viral Load; Viral Proteins | 2016 |
Low hemagglutinin antigen dose influenza vaccines adjuvanted with AS03 alter the long-term immune responses in BALB/c mice.
Topics: alpha-Tocopherol; Animals; Antibody-Producing Cells; CD4-Positive T-Lymphocytes; Cytokines; Drug Combinations; Enzyme-Linked Immunospot Assay; Female; Flow Cytometry; Hemagglutinin Glycoproteins, Influenza Virus; Influenza Vaccines; Injections, Intramuscular; Mice, Inbred BALB C; Polysorbates; Squalene | 2017 |
α-Tocopherol, β-carotene, lutein, squalene and secoiridoids in seven monocultivar Italian extra-virgin olive oils.
Topics: alpha-Tocopherol; beta Carotene; Food Analysis; Iridoids; Italy; Lutein; Olive Oil; Squalene | 2017 |
Production, purification and immunogenicity of recombinant Ebola virus proteins - A comparison of Freund's adjuvant and adjuvant system 03.
Topics: Adjuvants, Immunologic; alpha-Tocopherol; Animals; Antibodies, Viral; Baculoviridae; Drug Combinations; Ebolavirus; Freund's Adjuvant; Guinea Pigs; Polysorbates; Rabbits; Recombinant Proteins; Squalene; Viral Proteins | 2017 |
Adjuvanted (AS03) A/H1N1 2009 Pandemic Influenza Vaccines and Solid Organ Transplant Rejection: Systematic Signal Evaluation and Lessons Learnt.
Topics: Adolescent; Adult; Aged; alpha-Tocopherol; Animals; Drug Combinations; Female; Graft Rejection; Humans; Influenza A Virus, H1N1 Subtype; Influenza Vaccines; Influenza, Human; Male; Mice; Middle Aged; Pharmacoepidemiology; Polysorbates; Product Surveillance, Postmarketing; Squalene; Young Adult | 2017 |
Antioxidative Protection of Squalene Adjuvant and Rabies Vaccine with Adjuvant.
Topics: Adjuvants, Immunologic; alpha-Tocopherol; Animals; Antibodies, Viral; Antigens, Viral; Antioxidants; beta Carotene; Drug Compounding; Drug Stability; Emulsions; Female; Mice, Inbred ICR; Rabies Vaccines; Squalene | 2017 |
Improved fruit α-tocopherol, carotenoid, squalene and phytosterol contents through manipulation of Brassica juncea 3-HYDROXY-3-METHYLGLUTARYL-COA SYNTHASE1 in transgenic tomato.
Topics: alpha-Tocopherol; Carotenoids; Fruit; Gene Expression Regulation, Plant; Hydroxymethylglutaryl-CoA Synthase; Mustard Plant; Phytosterols; Plant Proteins; Solanum lycopersicum; Squalene | 2018 |
Autoimmune diseases and vaccines.
Topics: Adjuvants, Immunologic; alpha-Tocopherol; Autoimmune Diseases; Drug Combinations; Guillain-Barre Syndrome; Humans; Influenza Vaccines; Influenza, Human; Meningococcal Infections; Meningococcal Vaccines; Narcolepsy; Papillomavirus Infections; Papillomavirus Vaccines; Polysorbates; Squalene | 2016 |
High Oxidation Stability of Tea Polyphenol-stabilized Highly Crosslinked UHMWPE Under an in Vitro Aggressive Oxidative Condition.
Topics: Antioxidants; Camellia sinensis; Catechin; Free Radicals; Joint Prosthesis; Oxidation-Reduction; Plant Extracts; Polyethylenes; Prosthesis Failure; Squalene; Time Factors; Vitamin E | 2019 |
Lipid Characteristics of Camellia Seed Oil.
Topics: alpha-Tocopherol; Camellia; Chemical Phenomena; Linoleic Acid; Oleic Acid; Palmitic Acid; Phytosterols; Plant Oils; Seeds; Squalene; Triglycerides; Triolein | 2019 |
Comparative pharmacokinetic and biodistribution study of two distinct squalene-containing oil-in-water emulsion adjuvants in H5N1 influenza vaccines.
Topics: Adjuvants, Immunologic; alpha-Tocopherol; Animals; Antigens; Drug Combinations; Emulsions; Female; Influenza A Virus, H5N1 Subtype; Influenza Vaccines; Injections, Intramuscular; Lymph Nodes; Male; Mice, Inbred BALB C; Polysorbates; Quadriceps Muscle; Squalene; Tissue Distribution | 2019 |
De novo transcriptome of Gymnema sylvestre identified putative lncRNA and genes regulating terpenoid biosynthesis pathway.
Topics: Chromosome Mapping; Erythritol; Gene Expression Profiling; Gene Expression Regulation, Plant; Gene Ontology; Genome, Plant; Gymnema sylvestre; India; Microsatellite Repeats; Molecular Sequence Annotation; Oleanolic Acid; Plants, Medicinal; RNA, Long Noncoding; Squalene; Sugar Phosphates; Terpenes; Transcriptome; Vitamin E | 2019 |
Formulation Design, Optimization and In Vivo Evaluations of an α-Tocopherol-Containing Self-Emulsified Adjuvant System using Inactivated Influenza Vaccine.
Topics: Adjuvants, Immunologic; alpha-Tocopherol; Animals; Emulsions; Female; Humans; Influenza A Virus, H1N1 Subtype; Influenza Vaccines; Influenza, Human; Mice; Mice, Inbred BALB C; Polysorbates; Squalene; Vaccines, Inactivated | 2019 |
Squalene-based multidrug nanoparticles for improved mitigation of uncontrolled inflammation in rodents.
Topics: Adenosine; alpha-Tocopherol; Animals; Antioxidants; Betacoronavirus; Coronavirus Infections; COVID-19; Disease Models, Animal; Drug Delivery Systems; Endotoxemia; Female; Immunologic Factors; Lipopolysaccharides; Male; Mice; Mice, Inbred BALB C; Mice, Inbred C57BL; Nanoparticles; Pandemics; Pneumonia, Viral; SARS-CoV-2; Squalene; Systemic Inflammatory Response Syndrome; Treatment Outcome | 2020 |
Reassessment of the risk of narcolepsy in children in England 8 years after receipt of the AS03-adjuvanted H1N1 pandemic vaccine: A case-coverage study.
Topics: Adolescent; alpha-Tocopherol; Child; Child, Preschool; Drug Combinations; England; Female; Humans; Influenza A Virus, H1N1 Subtype; Influenza Vaccines; Influenza, Human; Male; Narcolepsy; Odds Ratio; Pandemics; Polysorbates; Risk Factors; Squalene; Surveys and Questionnaires; Vaccination | 2020 |
Impact of hydrothermal processing on squalene, α-tocopherol, and fatty acid content in Job's tears grain milled fractions: evaluation of their storage stability.
Topics: alpha-Tocopherol; Coix; Fatty Acids; Food Handling; Food Storage; Hot Temperature; Seeds; Squalene | 2021 |
Lack of effects on female fertility or pre- and postnatal development of offspring in rats after exposure to AS03-adjuvanted recombinant plant-derived virus-like particle vaccine candidate for COVID-19.
Topics: alpha-Tocopherol; Animals; Animals, Newborn; Antibodies, Viral; COVID-19; COVID-19 Vaccines; Drug Combinations; Embryonic Development; Female; Fertility; Fetal Development; Immunoglobulin G; Maternal-Fetal Exchange; Nicotiana; Polysorbates; Pregnancy; Rats, Sprague-Dawley; Recombinant Proteins; SARS-CoV-2; Spike Glycoprotein, Coronavirus; Squalene; Vaccines, Virus-Like Particle | 2022 |
Safety, immunogenicity, and protection provided by unadjuvanted and adjuvanted formulations of a recombinant plant-derived virus-like particle vaccine candidate for COVID-19 in nonhuman primates.
Topics: Adjuvants, Immunologic; alpha-Tocopherol; Animals; Antibodies, Neutralizing; Antibodies, Viral; COVID-19; COVID-19 Vaccines; Disease Models, Animal; Drug Combinations; Drug Compounding; Immunity, Humoral; Immunogenicity, Vaccine; Macaca mulatta; Male; Nicotiana; Pandemics; Polysorbates; Recombinant Proteins; SARS-CoV-2; Spike Glycoprotein, Coronavirus; Squalene; Treatment Outcome; Vaccination; Vaccines, Virus-Like Particle | 2022 |
Insect cuticular compounds affect Conidiobolus coronatus (Entomopthorales) sporulation and the activity of enzymes involved in fungal infection.
Topics: Acetylglucosaminidase; alpha-Tocopherol; Animals; Conidiobolus; Fatty Acids; Horses; Humans; Insecta; Lipase; Moths; Oleic Acid; Pancreatic Elastase; Sheep; Spores, Fungal; Squalene; Zygomycosis | 2022 |
A-910823, a squalene-based emulsion adjuvant, induces T follicular helper cells and humoral immune responses
Topics: Adjuvants, Immunologic; Adjuvants, Pharmaceutic; alpha-Tocopherol; Animals; COVID-19; Emulsions; Humans; Immunity, Humoral; Mice; SARS-CoV-2; Squalene; T Follicular Helper Cells | 2023 |