Page last updated: 2024-08-21

d-alpha tocopherol and saquinavir

d-alpha tocopherol has been researched along with saquinavir in 6 studies

Research

Studies (6)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's2 (33.33)29.6817
2010's4 (66.67)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A1
Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K1
Griffin, BT; O'Driscoll, CM1
Chao, Y; Grigorian, A; Hurford, R; Langford, TD; Patrick, C1
Geldenhuys, WJ; Lockman, PR; Manda, VK; Mittapalli, RK1
Davis, BM; Davis, S; O'Shea, P; Petrov, PG; Richens, JL; Vere, KA; Winlove, CP1

Reviews

1 review(s) available for d-alpha tocopherol and saquinavir

ArticleYear
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
    Drug discovery today, 2016, Volume: 21, Issue:4

    Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk

2016

Other Studies

5 other study(ies) available for d-alpha tocopherol and saquinavir

ArticleYear
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
    Chemical research in toxicology, 2010, Volume: 23, Issue:1

    Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship

2010
A comparison of intestinal lymphatic transport and systemic bioavailability of saquinavir from three lipid-based formulations in the anaesthetised rat model.
    The Journal of pharmacy and pharmacology, 2006, Volume: 58, Issue:7

    Topics: Anesthesia; Animals; Biological Availability; Biological Transport; Excipients; HIV Protease Inhibitors; Intestinal Absorption; Intestinal Mucosa; Lymph; Male; Micelles; Oleic Acid; Polyethylene Glycols; Rats; Rats, Wistar; Saquinavir; Succinates; Triglycerides; Vitamin E

2006
Alterations in the Notch4 pathway in cerebral endothelial cells by the HIV aspartyl protease inhibitor, nelfinavir.
    BMC neuroscience, 2008, Feb-26, Volume: 9

    Topics: Aspartic Acid Endopeptidases; Cell Survival; Cells, Cultured; Cerebral Arteries; Cerebral Veins; Endothelial Cells; Frontal Lobe; HIV Protease Inhibitors; Humans; Indinavir; Nelfinavir; Oxidative Stress; Phosphorylation; Proto-Oncogene Proteins; Reactive Oxygen Species; Receptor, Notch1; Receptor, Notch4; Receptors, Notch; Repressor Proteins; Ritonavir; Saquinavir; Vitamin E

2008
Chronic exposure to nicotine and saquinavir decreases endothelial Notch-4 expression and disrupts blood-brain barrier integrity.
    Journal of neurochemistry, 2010, Volume: 115, Issue:2

    Topics: Analysis of Variance; Animals; Blood-Brain Barrier; Brain; Chromatography, High Pressure Liquid; Dose-Response Relationship, Drug; Drug Delivery Systems; Drug Interactions; Endothelial Cells; HIV Protease Inhibitors; Male; Membrane Proteins; Nicotine; Oxidative Stress; Phosphoproteins; Proto-Oncogene Proteins; Rats; Rats, Inbred F344; Reactive Oxygen Species; Receptor, Notch4; Receptors, Notch; Saquinavir; Smoking; Vitamin E; Zonula Occludens-1 Protein

2010
α-Tocopherols modify the membrane dipole potential leading to modulation of ligand binding by P-glycoprotein.
    Journal of lipid research, 2015, Volume: 56, Issue:8

    Topics: alpha-Tocopherol; ATP Binding Cassette Transporter, Subfamily B, Member 1; Cell Membrane; Fluoresceins; Fluorescent Dyes; Humans; Jurkat Cells; Ketocholesterols; Ligands; Membrane Potentials; Models, Molecular; Molecular Conformation; Phosphatidylethanolamines; Protein Binding; Pyridinium Compounds; Saquinavir; Unilamellar Liposomes

2015