d-alpha tocopherol has been researched along with probucol in 139 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 2 (1.44) | 18.7374 |
| 1990's | 93 (66.91) | 18.2507 |
| 2000's | 31 (22.30) | 29.6817 |
| 2010's | 12 (8.63) | 24.3611 |
| 2020's | 1 (0.72) | 2.80 |
| Authors | Studies |
|---|---|
| Aizawa, Y; Fujita, T; Hasegawa, K; Horikoshi, H; Kanai, T; Kurumada, T; Yoshioka, T | 1 |
| Baltaze, JP; Breugnot, C; Lenaers, A; Lewin, G; Poisson, J; Privat, S; Rolland, Y; Vilaine, JP | 1 |
| Carbonneau, MA; Cartron, E; Descomps, B; Fouret, G; Léger, CL | 1 |
| Chandrasekar, D; Krishnaiah, P; Raju, TV; Ramakrishna, S; Ravikumar, K; Ravinder, K; Reddy, VL; Srinivasulu, M; Venkataramana, G; Venkateswarlu, Y | 1 |
| Baltas, M; Bedos-Belval, F; Delomenède, M; Duran, H; Lapeyre, C; Nègre-Salvayre, A | 1 |
| Baltas, M; Bedos-Belval, F; Delomenède, M; Duran, H; Gornitzka, H; Negre-Salvayre, A; Rakotondramanana, DL; Rasoanaivo, P | 1 |
| Baltas, M; Bedos-Belval, F; Delomenède, M; Duran, H; Nègre-Salvayre, A; Vindis, C | 1 |
| Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A | 1 |
| Morita, M; Naito, Y; Niki, E; Yoshikawa, T | 1 |
| Elguero, J; Silva, AMS; Silva, VLM | 1 |
| Breugnot, C; Iliou, JP; Lenaers, A; Privat, S; Robin, F; Vilaine, JP | 1 |
| Gotoh, N; Komuro, E; Niki, E; Noguchi, N; Shimizu, K; Tsuchiya, J | 1 |
| Bocan, TM; Brown, EQ; Mazur, MJ; Mueller, SB; Newton, RS; Uhlendorf, PD | 1 |
| Lorimer, AR; Oldroyd, KG; Packard, CJ; Paterson, JR; Rumley, AG; Shepherd, J; Smellie, WS; Tait, GW | 1 |
| McLean, LR; Ohlweiler, DF; Parker, RA; Thomas, CE | 1 |
| Hanna, AN; Kauffman, EM; Newman, HA; Sharma, HM | 2 |
| Guivarc'h, P; Iliou, JP; Jourd'heuil, D; Robin, F; Serkiz, B; Vilaine, JP; Volland, JP | 1 |
| Arístegui, R; Baumstark, MW; Berg, A; Frey, I; Keul, J; Zöller, T | 1 |
| Babiy, AV; Gebicki, JM; Sullivan, DR; Willey, K | 1 |
| Bonin, PD; Singh, JP | 1 |
| Fujita, H; Ihara, Y; Kajinami, K; Kamisaka, K; Kibata, M; Mabuchi, H; Namba, R; Nobukuni, K; Ohshima, K; Shirabe, T | 1 |
| Mimura, K; Yukawa, S | 1 |
| Akeson, AL; Jackson, RL; Mosher, LB; Thomas, CE; Woods, CW | 1 |
| Asai, K; Funaki, C; Hayashi, T; Kuzuya, F; Kuzuya, M; Naito, M; Yamada, K | 1 |
| Grundy, SM; Jialal, I | 1 |
| Brenner, DA; Chojkier, M; Houglum, K | 1 |
| Kimura, H; Kimura, S; Nakano, M; Sakurai, T | 1 |
| Chisolm, GM | 1 |
| Alomar, Y; Negre-Salvayre, A; Salvayre, R; Troly, M | 1 |
| Asai, K; Funaki, C; Hayashi, T; Kuzuya, F; Kuzuya, M; Naito, M | 1 |
| Asada, Y; Hayashi, T; Kisanuki, A; Sumiyoshi, A; Tanimura, N | 1 |
| Ballantine, JA; Carpenter, KL; Enright, JH; Fussell, B; Mitchinson, MJ | 1 |
| Abe, A; Maeda, S; Muto, Y; Noma, A; Okuno, M | 1 |
| Auclair, M; Breugnot, C; Lenaers, A; Mazière, C; Mazière, JC; Morlière, P; Salmon, S; Santus, R | 1 |
| Chisolm, GM; Morel, DW | 1 |
| Bolaffi, JL; Grodsky, GM; Rodd, GG; Wang, J | 1 |
| Arfors, KE; Frei, B; Lehr, HA | 1 |
| Fukuda, N; Nagata, Y; Sakai, T; Shiotsuki, Y; Shiroi, S; Tani, T; Yamamoto, K | 2 |
| Dewhurst, M; Karasu, C; Stevens, EJ; Tomlinson, DR | 1 |
| Cap, M; Gill, BT; Parker, RA; Sabrah, T | 1 |
| Parthasarathy, S; Santanam, N | 1 |
| Carpenter, KL; Hardwick, SJ; Law, NS; Marchant, CE; Mitchinson, MJ; van der Veen, C | 2 |
| Braun, S; von Bruchhausen, F | 1 |
| Arfors, KE; Carew, TE; Frei, B; Lehr, HA; Olofsson, AM | 1 |
| Ager, AL; Fontela, R; Levander, OA; Morris, VC | 1 |
| Brennan, GM; Bruce, I; Johnston, GD; McDowell, IF; McEneny, J; McVeigh, GE; Nicholls, DP; Trimble, ER; Young, IS | 1 |
| de la Llera-Moya, M; Friday, KE; Morel, DW | 1 |
| Dujovne, CA; Fan, J; Gerrond, LL; Harris, WS; Muzio, F | 1 |
| Bottoms, MA; Hunt, JV; Lyell, V; Mitchinson, MJ; Taylor, SE | 1 |
| Elstner, EF; Kögl, C; Schneider, W | 1 |
| Arimoto, T; Ito, T; Kamiya, K; Nakano, M; Ushijima, Y | 1 |
| Demacker, PN; Kleinveld, HA; Stalenhoef, AF | 1 |
| Heinecke, JW; Mueller, DM; Savenkova, ML | 1 |
| Kaji, K; Kaneko, T; Matsuo, M | 1 |
| Bouzom, F; Breugnot, C; Guillonneau, C; Lenaers, A; Privat, S; Regnier, G; Vilaine, JP | 1 |
| Boulet, L; Davignon, J; de Langavant, GC; Dubreuil-Quidoz, S; Leboeuf, N; Lussier-Cacan, S; Naruszewicz, M; Roederer, G | 1 |
| Demacker, PN; Hijmans, AG; Kleinveld, HA; Stalenhoef, AF | 1 |
| Antonov, IA; Kosenkov, EI; Kosykh, VA; Lakeev, IuV; Repin, VS; Tikhomirov, OIu; Tsibul'skiĭ, VP | 1 |
| Andersen, HO; Elinder, LS; Hansen, BF; Holm, P; Kjeldsen, K; Nordestgaard, BG; Stender, S | 1 |
| Cao, R; Chappey, O; Guillausseau, PJ; Hori, O; Schmidt, AM; Stern, D; Wautier, JL; Wautier, MP; Zoukourian, C | 1 |
| Rojstaczer, N; Triggle, DJ | 1 |
| Kobuchi, H; Matsugo, S; Packer, L; Traber, MG; Tritschler, HJ; Yan, LJ | 1 |
| Ameshima, S; Ishizaki, T; Kishi, Y; Miyabo, S; Nakai, T; Sasaki, F | 1 |
| Bisby, RH; Johnson, SA; Parker, AW | 1 |
| Guyton, JR; Hughes, H; Karsan, D; Lenz, ML; Mathews, B; Selinger, E; Smith, CV | 1 |
| Ostlund-Lindqvist, AM; Pettersson, KS; Westerlund, C | 1 |
| Darley-Usmar, V; Fleetwood, G; O'Leary, VJ; Stone, D; Tilling, L | 1 |
| Chappey, B; Moatti, N; Myara, I; Pech-Amsellem, MA; Pico, I; Vedie, B | 1 |
| Robenek, H; Severs, NJ; Trach, CC; Wülfroth, PM | 1 |
| Barnett, J; Grasse, B; Reaven, P | 1 |
| Chung, HK; Jeong, JY; Kim, BC; Kim, YS; Lee, HS; Zhang, YZ | 1 |
| Dittrich, P; Graier, WF; Hoebel, BG; Kostner, GM; Simecek, S; Wascher, TC | 1 |
| Olsson, AG; Yuan, XM | 1 |
| Harada, N; Hidaka, H; Kashiwagi, A; Kikkawa, R; Kojima, H; Maegawa, H; Nishio, Y; Takahara, N | 1 |
| Bilodeau, L; Bourassa, M; Cöté, G; de Guise, P; Doucet, S; Lambert, J; Lespérance, J; Nattel, S; Tardif, JC | 1 |
| Kalra, VK; Rattan, V; Shen, Y; Sultana, C | 1 |
| Hirano, R; Igarashi, O; Itakura, H; Iwamoto, T; Kondo, K | 1 |
| Hodis, H; Sevanian, A | 1 |
| Jorge, PA | 1 |
| Azzi, A; Moser, U; Ozer, NK; San, T; Sirikçi, O; Taha, S | 1 |
| Bird, DA; Fruebis, J; Palinski, W; Pattison, J | 1 |
| Hong, CY; Lin, SJ; Shiao, MS; Wu, P; Wu, YJ | 1 |
| Bykhovskii, VY; Gessler, NN; Gomboeva, SB; Khomich, TI; Moiseenok, AG; Shumaev, KB | 1 |
| Drukker, A; Eddy, AA | 1 |
| Bird, DA; Fruebis, J; Palinski, W; Steinberg, D; Tangirala, RK; Witztum, JL | 1 |
| Dailly, E; Tillement, JP; Urien, S | 1 |
| Koga, T; Moro, K; Terao, J | 1 |
| Haklar, G; Ozer, NK; Sirikçi, O; Yalçin, AS | 1 |
| Behr, SR; Schwenke, DC | 2 |
| Hiramitsu, T; Ito, T; Nakano, M | 1 |
| Bonnefont-Rousselot, D; Delattre, J; Gardès-Albert, M; Jore, D; Segaud, C | 1 |
| Kano, H; Kohno, M; Minami, M; Yasunari, K; Yokokawa, K; Yoshikawa, J | 1 |
| Carpenter, KL; Freeman, MA; Mitchinson, MJ; Müller, K | 1 |
| Black, CM; Bruckdorfer, KR; Bunce, TD; Denton, CP; Dorado, MB; Howell, K; Roberts, Z; Wilson, H | 1 |
| Knox, FG; Liang, M | 1 |
| Abdel-Naim, AB; Abdel-Wahab, MH; Attia, FF | 1 |
| Byun, J; Fabjan, JS; Heinecke, JW; Mueller, DM | 1 |
| Fruebis, J; Napoli, C; Palinski, W; Shelton, D; Silvestre, M | 1 |
| Ishi, H; Kanoh, H; King, GL; Koya, D; Lee, IK | 1 |
| Niki, E; Nishino, K; Noguchi, N | 1 |
| El-Swefy, S; El-Sweidy, M; Meydani, M; Ordovas, JM; Schaefer, EJ; Seman, LJ; Sevanian, A; Smith, DE; van Dongen, D | 1 |
| Hashimura, Y; Kubota, H; Ohmizu, H; Suzuki, T; Suzumura, K | 1 |
| Lahoz Rallo, C; Mostaza Prieto, JM; Peña Valverde, R | 1 |
| Baba, N; Kaneko, T; Matsuo, M | 1 |
| Azzi, A; Ozer, NK | 1 |
| Csallany, AS; Gallaher, DD; Kim, SS | 1 |
| Alberto, P; Cerinic, MM; Falcini, F; Fernanda, F; Gabriele, S; Generini, S; Marco, MC; Pignone, A; Sergio, G; Simonini, G | 1 |
| Beisiegel, U; Braesen, JH; Djahansouzi, S; Koenig, K; Kontush, A | 1 |
| Itakura, H | 1 |
| Mashima, R; Stocker, R; Witting, PK | 1 |
| Iwasaki, K; Kuroda, N; Nakashima, A; Nakashima, K; Ohtawa, M; Wada, M | 1 |
| Choi, JY; Chung, MH; Han, B; Kim, JH; Kim, JM; Kim, MS; Kim, SK; Kim, SY; Lee, HK; Park, KS | 1 |
| Bok, SH; Choi, MS; Jang, MK; Jeon, SM; Jeong, TS; Kim, YH; Nam, KT; Park, YB | 1 |
| Kunieda, T; Murase, H; Naito, Y; Tanaka, T; Tanigawa, T; Terao, J; Toyokuni, S; Yoshida, N; Yoshikawa, T | 1 |
| Bach, H; Beisiegel, U; Bräsen, JH; Heinle, H; Koenig, K; Kontush, A; Stocker, R; Witting, PK; Ylä-Herttuala, S | 1 |
| Ashidate, K; Hayashi, H; Hirata, Y; Kawamura, M; Miyazaki, S; Teramoto, T; Tohda, H | 1 |
| Gotto, AM | 1 |
| Belenkov, YN; Kaminnyi, AI; Konovalova, GG; Kukharchuk, VV; Lankin, VZ; Pisarenko, OI; Shumaev, KB; Tikhaze, AK | 1 |
| Huang, HY; Lin, CC; Liu, HC; Mao, SJ; Tseng, CF | 1 |
| Choi, MS; Do, KM; Huh, TL; Jeon, SM; Kwon, OS; Lee, WH; Park, T; Park, YB | 1 |
| Comar, KM; Sterling, RK | 1 |
| Murata, T; Nagai, H; Okamoto, N; Tamai, H; Tanaka, H | 1 |
| März, W; Siekmeier, R; Steffen, C | 1 |
| Ishihara, M; Ito, M; Kojima, R | 1 |
| Dhawan, A; Dziechciarz, P; Horvath, A; Socha, P; Szajewska, H; Vajro, P | 1 |
| Arai, H; Kokubu, T; Rotzoll, DE; Shichiri, M; Takanezawa, Y; Tamai, H; Ueda, K; Yoshida, Y | 1 |
| Fujino, H; Kawashima, T; Makiyama, T; Matsuzawa, Y; Murayama, T; Yamaura, E; Yamazaki, R | 1 |
| Calleja, MA; Faus, MJ; Gil, A; Montero-Meléndez, T; Montero-Meterdez, T; Suárez, A; Torres, MI; Vieites, JM | 1 |
| Fan, Z; Fang, X; Sha, X; Wu, J | 1 |
| Cui, J; Gu, W; Jiang, S; Li, Y; Liu, Z; Niu, B; Zhang, Z | 1 |
| Atef, E; Karzuon, B; Raut, S | 1 |
| Hagihara, Y; Herbas, MS; Ishida, N; Kume, A; Shichiri, M; Suzuki, H; Yoshida, Y | 1 |
| Herbas, MS; Ishida, N; Kume, A; Shichiri, M; Suzuki, H | 1 |
| Berco, M; Bhavnani, BR; Cecutti, A; Gerulath, A; Woolever, AC | 1 |
| Chen, W; Feng, X; Li, L; Xu, S; Zhang, L; Zhang, S | 1 |
15 review(s) available for d-alpha tocopherol and probucol
| Article | Year |
|---|---|
Current progress on antioxidants incorporating the pyrazole core.
Topics: Animals; Antioxidants; Drug Discovery; Humans; Oxidative Stress; Pyrazoles; Structure-Activity Relationship | 2018 |
Antioxidants and atherosclerosis: a current assessment.
Topics: Animals; Antioxidants; Arteriosclerosis; Cholesterol, Dietary; Free Radical Scavengers; Humans; Lipoproteins, LDL; Probucol; Vitamin E | 1991 |
The potential of antioxidants to prevent atherosclerosis development and its clinical manifestations.
Topics: Angioplasty, Balloon, Coronary; Animals; Anticholesteremic Agents; Antioxidants; Arteries; Arteriosclerosis; Female; Humans; Lipoproteins, LDL; Male; Oxidation-Reduction; Probucol; Vasodilation; Vitamin E | 1996 |
Antioxidants in the prevention of atherosclerosis.
Topics: Anticholesteremic Agents; Antioxidants; Arteriosclerosis; beta Carotene; Humans; Iron Chelating Agents; Probucol; Vitamin E | 1996 |
Antioxidants and atherosclerosis: an overview.
Topics: Animals; Anticholesteremic Agents; Antioxidants; Arteriosclerosis; Disease Models, Animal; Humans; Probucol; Vitamin E | 1997 |
[Endothelium, lipids and atherosclerosis].
Topics: Animals; Anticholesteremic Agents; Arteriosclerosis; Endocytosis; Endothelium, Vascular; Foam Cells; Humans; Hypercholesterolemia; Lipoproteins, LDL; Pravastatin; Probucol; Rabbits; Vitamin E | 1997 |
[Should antioxidants be recommended for the prevention of cardiovascular diseases?].
Topics: Antioxidants; beta Carotene; Cardiovascular Diseases; Flavonoids; Humans; Probucol; Vitamin E | 2000 |
Emerging potentials for an antioxidant therapy as a new approach to the treatment of systemic sclerosis.
Topics: Antioxidants; Ascorbic Acid; beta Carotene; Endothelium, Vascular; Humans; In Vitro Techniques; Melatonin; Nitric Oxide; Oxidative Stress; Pregnatrienes; Probucol; Raynaud Disease; Reactive Oxygen Species; Reperfusion Injury; Resveratrol; Scleroderma, Systemic; Selenium; Stilbenes; Vitamin E | 2000 |
[Antioxidants].
Topics: Animals; Antioxidants; Arteriosclerosis; Ascorbic Acid; Carotenoids; Clinical Trials as Topic; Coronary Disease; Fatty Acids, Monounsaturated; Flavonoids; Fluvastatin; Humans; Indoles; Oxidative Stress; Phenols; Polymers; Polyphenols; Probucol; Vitamin E | 2001 |
Oxidants and antioxidants in atherosclerosis.
Topics: Antioxidants; Arteriosclerosis; Free Radicals; Humans; Lipid Peroxidation; Lipoproteins, LDL; Nitric Oxide; Oxidants; Peroxidase; Probucol; Vitamin E | 2001 |
Antioxidants, statins, and atherosclerosis.
Topics: Animals; Antioxidants; Ascorbic Acid; beta Carotene; Clinical Trials as Topic; Coronary Artery Disease; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hyperlipidemias; Probucol; Rabbits; Vitamin E | 2003 |
Review article: Drug therapy for non-alcoholic fatty liver disease.
Topics: Angiotensin-Converting Enzyme Inhibitors; Antioxidants; Ascorbic Acid; Betaine; Cholagogues and Choleretics; Enzyme Inhibitors; Fatty Liver; Humans; Hypoglycemic Agents; Lipotropic Agents; Metformin; Pentoxifylline; Probucol; Thiazolidinediones; Ursodeoxycholic Acid; Vitamin E | 2006 |
[Can antioxidants prevent atherosclerosis?].
Topics: Adult; Age Factors; Aged; Aged, 80 and over; Animals; Anticholesteremic Agents; Antioxidants; Ascorbic Acid; Atherosclerosis; beta Carotene; Case-Control Studies; Dietary Supplements; Female; Follow-Up Studies; Humans; Male; Meta-Analysis as Topic; Middle Aged; Oxidants; Primary Prevention; Probucol; Prospective Studies; Randomized Controlled Trials as Topic; Reactive Oxygen Species; Risk; Risk Factors; Sex Factors; Time Factors; Tocopherols; Vitamin E; Vitamins | 2006 |
Pharmacological interventions for nonalcoholic fatty liver disease in adults and in children: a systematic review.
Topics: Acetylcysteine; Adult; Alanine Transaminase; Aspartate Aminotransferases; Carnitine; Child; Dietary Supplements; Drug Synergism; Drug Therapy, Combination; Fatty Liver; Humans; Hypoglycemic Agents; Liver; Metformin; Pioglitazone; Probucol; Randomized Controlled Trials as Topic; Thiazolidinediones; Ursodeoxycholic Acid; Vitamin E | 2009 |
Natural products: The role and mechanism in low-density lipoprotein oxidation and atherosclerosis.
Topics: Abietanes; Antioxidants; Atherosclerosis; Biological Products; Catechin; Dietary Supplements; Humans; Lipoproteins, LDL; Lycopene; Phytotherapy; Plant Extracts; Probucol; Quercetin; Resveratrol; Vitamin E | 2021 |
4 trial(s) available for d-alpha tocopherol and probucol
| Article | Year |
|---|---|
Reduction of serum lipoprotein(a) levels in hyperlipidaemic patients with alpha-tocopheryl nicotinate.
Topics: Adult; Aged; Apolipoprotein C-II; Apolipoproteins C; Cholesterol; Cholesterol, HDL; Female; Humans; Hyperlipidemias; Lipoprotein(a); Lipoproteins; Male; Middle Aged; Nicotinic Acids; Probucol; Vitamin E | 1990 |
The effect of probucol and vitamin E treatment on the oxidation of low-density lipoprotein and forearm vascular responses in humans.
Topics: Adult; Cholesterol, LDL; Double-Blind Method; Drug Administration Schedule; Drug Therapy, Combination; Female; Forearm; Humans; Hyperlipidemias; Hypolipidemic Agents; Lovastatin; Male; Middle Aged; Oxidation-Reduction; Probucol; Regional Blood Flow; Simvastatin; Vitamin E | 1994 |
Probucol and multivitamins in the prevention of restenosis after coronary angioplasty. Multivitamins and Probucol Study Group.
Topics: Angioplasty, Balloon, Coronary; Antioxidants; Ascorbic Acid; beta Carotene; Coronary Angiography; Coronary Disease; Double-Blind Method; Drug Therapy, Combination; Female; Humans; Male; Middle Aged; Probucol; Recurrence; Treatment Outcome; Vitamin E | 1997 |
Probucol improves symptoms and reduces lipoprotein oxidation susceptibility in patients with Raynaud's phenomenon.
Topics: Anticholesteremic Agents; Antioxidants; Ascorbic Acid; Cohort Studies; Humans; Lipoproteins; Lipoproteins, LDL; Nifedipine; Oxidation-Reduction; Probucol; Raynaud Disease; Scleroderma, Systemic; Triglycerides; Vasodilator Agents; Vitamin E | 1999 |
120 other study(ies) available for d-alpha tocopherol and probucol
| Article | Year |
|---|---|
Studies on hindered phenols and analogues. 1. Hypolipidemic and hypoglycemic agents with ability to inhibit lipid peroxidation.
Topics: Animals; Hypoglycemic Agents; Hypolipidemic Agents; Lipid Peroxidation; Male; Mice; Mice, Inbred BALB C; Phenols; Rats; Structure-Activity Relationship | 1989 |
Synthesis and evaluation of 3',5'-di-tert-butyl-4'-hydroxyflavones as potential inhibitors of low density lipoprotein (LDL) oxidation.
Topics: Antioxidants; Flavonoids; Humans; In Vitro Techniques; Lipid Peroxidation; Lipoproteins, LDL; Magnetic Resonance Spectroscopy; Oxidation-Reduction; Thiobarbituric Acid Reactive Substances | 1995 |
Specific antioxidant activity of caffeoyl derivatives and other natural phenolic compounds: LDL protection against oxidation and decrease in the proinflammatory lysophosphatidylcholine production.
Topics: Antioxidants; Caffeic Acids; Humans; Inflammation Mediators; Lipoproteins, LDL; Lysophosphatidylcholines; Oxidation-Reduction; Phenols | 2001 |
New lamellarin alkaloids from the Indian ascidian Didemnum obscurum and their antioxidant properties.
Topics: Alkaloids; Animals; Antioxidants; Coumarins; Crystallography, X-Ray; Heterocyclic Compounds, 4 or More Rings; India; Inhibitory Concentration 50; Molecular Structure; Nuclear Magnetic Resonance, Biomolecular; Urochordata | 2004 |
Design, synthesis, and evaluation of pharmacological properties of cinnamic derivatives as antiatherogenic agents.
Topics: Antioxidants; Atherosclerosis; Cell Line; Cell Survival; Cinnamates; Cytoprotection; Drug Design; Endothelium, Vascular; Humans; Lipoproteins, LDL; Microcirculation; Probucol | 2005 |
Synthesis of ferulic ester dimers, functionalisation and biological evaluation as potential antiatherogenic and antiplasmodial agents.
Topics: Animals; Antioxidants; Atherosclerosis; Cell Survival; Coumaric Acids; Dimerization; Endothelium, Vascular; Esters; Humans; Leukemia P388; Lipoproteins, LDL; Mice; Molecular Structure; Parasitic Sensitivity Tests; Plasmodium falciparum; Thiobarbituric Acid Reactive Substances | 2007 |
Development of novel antiatherogenic biaryls: design, synthesis, and reactivity.
Topics: Antioxidants; Cell Line; Foam Cells; Humans; Hydrazines; Hydrazones; Lipoproteins, LDL; Models, Molecular; Organophosphonates; Oxidation-Reduction; Phthalazines; Protein Carbonylation; Structure-Activity Relationship | 2008 |
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship | 2010 |
Inhibition of plasma lipid oxidation induced by peroxyl radicals, peroxynitrite, hypochlorite, 15-lipoxygenase, and singlet oxygen by clinical drugs.
Topics: Animals; Antioxidants; Antipyrine; Arachidonate 15-Lipoxygenase; Edaravone; Free Radicals; Hypochlorous Acid; Lipid Metabolism; Lipids; Mice; Oxidants; Oxidation-Reduction; Peroxides; Peroxynitrous Acid; Plasma; Probucol; Singlet Oxygen | 2016 |
In vitro and ex vivo inhibition of the modification of low-density lipoprotein by indapamide.
Topics: Animals; Bepridil; Biphenyl Compounds; Cells, Cultured; Cholesterol; Chromatography, High Pressure Liquid; Copper; Diuretics; Electrophoresis, Agar Gel; Endothelium; Free Radical Scavengers; Humans; Indapamide; Lipid Peroxidation; Lipoproteins, LDL; Picrates; Probucol; Rabbits; Spectrophotometry, Ultraviolet; Vitamin E | 1992 |
Antioxidant activities of probucol against lipid peroxidations.
Topics: Antioxidants; Benzhydryl Compounds; Copper; Electron Spin Resonance Spectroscopy; Free Radicals; Hexanes; Humans; Linoleic Acids; Lipid Peroxidation; Lipoproteins, LDL; Liposomes; Oxidation-Reduction; Phosphatidylcholines; Probucol; Vitamin E | 1992 |
Antiatherosclerotic effects of antioxidants are lesion-specific when evaluated in hypercholesterolemic New Zealand white rabbits.
Topics: Animals; Antioxidants; Aorta; Arteriosclerosis; Ascorbic Acid; Blood Vessels; Cholesterol; Cholesterol Esters; Femoral Artery; Hypercholesterolemia; Lipids; Lipoproteins; Male; Probucol; Rabbits; Vitamin E | 1992 |
Probucol reduces plasma lipid peroxides in man.
Topics: Adult; Cholesterol; Humans; Hyperlipidemias; Lipid Peroxides; Male; Middle Aged; Probucol; Vitamin E | 1992 |
Ascorbate and phenolic antioxidant interactions in prevention of liposomal oxidation.
Topics: Antioxidants; Ascorbic Acid; Drug Synergism; Lipid Peroxidation; Liposomes; Oxidation-Reduction; Phenols; Phosphatidylcholines; Probucol; Sulfides; Vitamin E | 1992 |
Inhibition of human low-density lipoprotein oxidation in vitro by Maharishi Ayur-Veda herbal mixtures.
Topics: Antioxidants; Ascorbic Acid; Copper; Dose-Response Relationship, Drug; Electrophoresis, Polyacrylamide Gel; Humans; In Vitro Techniques; Lipoproteins, LDL; Medicine, Ayurvedic; Oxidation-Reduction; Phytotherapy; Plant Extracts; Probucol; Thiobarbituric Acid Reactive Substances; Vitamin E | 1992 |
Kinetics of photoperoxidation of arachidonic acid: molecular mechanisms and effects of antioxidants.
Topics: 4,5-Dihydro-1-(3-(trifluoromethyl)phenyl)-1H-pyrazol-3-amine; 5,8,11,14-Eicosatetraynoic Acid; Antioxidants; Arachidonic Acid; beta Carotene; Carotenoids; Free Radicals; Indomethacin; Kinetics; Oxidation-Reduction; Peroxides; Photochemistry; Photosensitizing Agents; Probucol; Vitamin E | 1992 |
Probucol, incorporated into LDL particles in vivo, inhibits generation of lipid peroxides more effectively than endogenous antioxidants alone.
Topics: Antioxidants; Cholesterol; Humans; Hypercholesterolemia; Lipid Peroxides; Lipoproteins, LDL; Male; Probucol; Vitamin E | 1992 |
Increased oxidizability of plasma lipoproteins in diabetic patients can be decreased by probucol therapy and is not due to glycation.
Topics: Adult; Arteriosclerosis; Diabetes Complications; Diabetes Mellitus; Female; Glycosylation; Humans; Lipid Peroxidation; Lipoproteins; Lipoproteins, HDL; Lipoproteins, LDL; Male; Middle Aged; Probucol; Vitamin E | 1992 |
Inhibition of proliferation of fibroblasts by lazaroids (21-aminosteroids).
Topics: Animals; Antioxidants; Cell Division; Cell Line; Cell Survival; DNA Replication; Ethylamines; Fibroblasts; Kinetics; L-Lactate Dehydrogenase; Mice; Mice, Inbred BALB C; Piperazines; Pregnatrienes; Probucol; Pyridines; Steroids; Vitamin E | 1991 |
A family of familial hypercholesterolemia with cerebral infarction and without coronary heart disease. An unusual case with corneal opacity, polyneuropathy and carpal tunnel syndrome in the family: therapy with probucol and tocopherol nicotinate.
Topics: Arteriosclerosis; Axons; Carpal Tunnel Syndrome; CD4-CD8 Ratio; Cerebral Infarction; Corneal Opacity; Female; Free Radicals; Hereditary Sensory and Motor Neuropathy; Humans; Hyperlipoproteinemia Type II; Lipoproteins, LDL; Middle Aged; Mosaicism; Nicotinic Acids; Probucol; Schwann Cells; Superoxide Dismutase; Turner Syndrome; Vitamin E | 1991 |
[Hyperlipidemia and drug treatment].
Topics: Arteriosclerosis; Carnitine; Cholestyramine Resin; Glomerulonephritis; Humans; Hyperlipidemias; Kidney Failure, Chronic; Niceritrol; Pantetheine; Pravastatin; Probucol; Vitamin E | 1991 |
Inhibition of IL-1 beta expression in THP-1 cells by probucol and tocopherol.
Topics: Cell Differentiation; Cell Line; Dose-Response Relationship, Drug; Humans; Interleukin-1; Leukemia, Experimental; Probucol; RNA, Messenger; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured; Vitamin E | 1991 |
Antioxidants stimulate endothelial cell proliferation in culture.
Topics: Animals; Antioxidants; Biological Factors; Butylated Hydroxytoluene; Catalase; Cattle; Cell Division; Cells, Cultured; Culture Media; Endothelium, Vascular; Mannitol; Probucol; Superoxide Dismutase; Thiobarbiturates; Vitamin E | 1991 |
Preservation of the endogenous antioxidants in low density lipoprotein by ascorbate but not probucol during oxidative modification.
Topics: Ascorbic Acid; beta Carotene; Carotenoids; Electrophoresis, Agar Gel; Humans; Lipid Peroxidation; Lipoproteins, LDL; Macrophages; Oxidation-Reduction; Probucol; Vitamin E | 1991 |
d-alpha-tocopherol inhibits collagen alpha 1(I) gene expression in cultured human fibroblasts. Modulation of constitutive collagen gene expression by lipid peroxidation.
Topics: 4,5-Dihydro-1-(3-(trifluoromethyl)phenyl)-1H-pyrazol-3-amine; Blotting, Northern; Cells, Cultured; Collagen; Dose-Response Relationship, Drug; Fibroblasts; Gene Expression; Humans; Lipid Peroxides; Methylene Blue; Probucol; RNA, Messenger; Transcription, Genetic; Vitamin E | 1991 |
Oxidative modification of glycated low density lipoprotein in the presence of iron.
Topics: Electrophoresis, Polyacrylamide Gel; Glucose; Glycation End Products, Advanced; Humans; Iron; Kinetics; Lipid Peroxidation; Lipoproteins, LDL; Molecular Weight; Oxidation-Reduction; Probucol; Vitamin E | 1991 |
Ultraviolet-treated lipoproteins as a model system for the study of the biological effects of lipid peroxides on cultured cells. III. The protective effect of antioxidants (probucol, catechin, vitamin E) against the cytotoxicity of oxidized LDL occurs in
Topics: Antioxidants; Catechin; Cell Line, Transformed; Copper; Humans; Kinetics; Lipid Peroxidation; Lipid Peroxides; Lipoproteins, LDL; Models, Biological; Oxidation-Reduction; Probucol; Ultraviolet Rays; Vitamin E | 1991 |
Probucol prevents oxidative injury to endothelial cells.
Topics: Animals; Antioxidants; Benzene Derivatives; Cattle; Cells, Cultured; Chromatography, High Pressure Liquid; Endothelium, Vascular; L-Lactate Dehydrogenase; Lipoproteins, LDL; Oxidation-Reduction; Probucol; Vitamin E | 1991 |
Aortic endothelial cell damage induced by beta-VLDL and macrophages in vitro.
Topics: Adenine; Animals; Antioxidants; Aorta, Thoracic; Catalase; Cells, Cultured; Endothelium, Vascular; Lipoproteins, VLDL; Macrophages; Male; Polyethylene Glycols; Probucol; Rabbits; Superoxide Dismutase; Swine; Vitamin E | 1990 |
Oxidation of cholesteryl linoleate by human monocyte-macrophages in vitro.
Topics: Arteriosclerosis; Butylated Hydroxytoluene; Cells, Cultured; Cholesterol Esters; Edetic Acid; Free Radicals; Humans; Hydroxycholesterols; Lipid Metabolism; Lipid Peroxidation; Macrophages; Monocytes; Oxidation-Reduction; Probucol; Vitamin E | 1990 |
Phenothiazines inhibit copper and endothelial cell-induced peroxidation of low density lipoprotein. A comparative study with probucol, butylated hydroxytoluene and vitamin E.
Topics: Animals; Butylated Hydroxytoluene; Cell Line; Chlorpromazine; Copper; Endothelium; Free Radical Scavengers; Lipid Peroxidation; Lipoproteins, LDL; Probucol; Rabbits; Trifluoperazine; Vitamin E | 1990 |
Antioxidant treatment of diabetic rats inhibits lipoprotein oxidation and cytotoxicity.
Topics: Animals; Antioxidants; Blood Glucose; Body Weight; Cell Survival; Cells, Cultured; Diabetes Mellitus, Experimental; Humans; Lipid Peroxides; Lipoproteins, LDL; Lipoproteins, VLDL; Male; Oxidation-Reduction; Probucol; Rats; Rats, Inbred Strains; Vitamin E | 1989 |
Interrelationship of changes in islet nicotine adeninedinucleotide, insulin secretion, and cell viability induced by interleukin-1 beta.
Topics: Amino Acid Oxidoreductases; Animals; Arginine; Arginine Vasopressin; beta-Endorphin; Cell Survival; Cells, Cultured; Colforsin; Corticosterone; Dynorphins; Glucose; Insulin; Insulin Secretion; Interleukin-1; Islets of Langerhans; Kinetics; Male; NAD; Niacinamide; Nitric Oxide Synthase; omega-N-Methylarginine; Probucol; Progesterone; Rats; Vitamin E | 1994 |
Vitamin C prevents cigarette smoke-induced leukocyte aggregation and adhesion to endothelium in vivo.
Topics: Animals; Aorta; Ascorbic Acid; Cell Adhesion; Cell Aggregation; Cricetinae; Endothelium, Vascular; Leukocytes; Mesocricetus; Microcirculation; Microscopy, Electron, Scanning; Microscopy, Fluorescence; Probucol; Reactive Oxygen Species; Smoke Inhalation Injury; Staining and Labeling; Superoxides; Vitamin E | 1994 |
Effect of dietary antioxidants on the susceptibility to hepatic microsomal lipid peroxidation in the rat.
Topics: Animals; Antioxidants; Butylated Hydroxytoluene; Cholesterol; Diet; Fatty Acids; Food, Fortified; Hypercholesterolemia; Lipid Metabolism; Lipid Peroxidation; Liver; Male; Microsomes, Liver; Phospholipids; Probucol; Rats; Rats, Wistar; Thiobarbituric Acid Reactive Substances; Vitamin E | 1995 |
Effects of anti-oxidant treatment on sciatic nerve dysfunction in streptozotocin-diabetic rats; comparison with essential fatty acids.
Topics: Animals; Antioxidants; Cholesterol; Diabetes Mellitus, Experimental; Fatty Acids, Essential; gamma-Linolenic Acid; Linoleic Acids; Male; Neural Conduction; Oenothera biennis; Peripheral Nervous System Diseases; Plant Oils; Probucol; Rats; Rats, Wistar; Sciatic Nerve; Triglycerides; Vitamin E | 1995 |
Relation of vascular oxidative stress, alpha-tocopherol, and hypercholesterolemia to early atherosclerosis in hamsters.
Topics: Animals; Antioxidants; Aorta; Arteriosclerosis; Corn Oil; Cricetinae; Diet, Atherogenic; Dose-Response Relationship, Drug; Food, Formulated; Hypercholesterolemia; Lipoproteins, LDL; Male; Mesocricetus; Oxidation-Reduction; Oxidative Stress; Probucol; Vitamin E | 1995 |
Paradoxical actions of antioxidants in the oxidation of low density lipoprotein by peroxidases.
Topics: Antioxidants; Humans; In Vitro Techniques; Linoleic Acid; Linoleic Acids; Lipoproteins, LDL; Models, Molecular; Peroxidases; Probucol; Structure-Activity Relationship; Tyrosine; Vitamin E | 1995 |
Oxidized low-density lipoprotein is cytotoxic to human monocyte-macrophages: protection with lipophilic antioxidants.
Topics: Adult; Antioxidants; Cell Survival; Chromatography, Gas; Cytotoxins; Humans; Lipoproteins, LDL; Macrophages; Monocytes; Oxidation-Reduction; Probucol; Vitamin E | 1995 |
Vitamin E or probucol as donors for oxidation of human low-density lipoprotein by peroxidases/H2O2.
Topics: Antioxidants; Chromans; Humans; Lipoproteins, LDL; Oxidation-Reduction; Peroxidases; Probucol; Vitamin E | 1994 |
Protection from oxidized LDL-induced leukocyte adhesion to microvascular and macrovascular endothelium in vivo by vitamin C but not by vitamin E.
Topics: Animals; Aorta; Ascorbic Acid; Cell Adhesion; Cell Aggregation; Cricetinae; Diet; Endothelium, Vascular; Leukocytes; Lipoproteins, LDL; Mesocricetus; Microscopy, Electron, Scanning; Microscopy, Fluorescence; Platelet Aggregation; Premedication; Probucol; Reactive Oxygen Species; Vitamin E | 1995 |
Protection against murine cerebral malaria by dietary-induced oxidative stress.
Topics: Animal Feed; Animals; Antioxidants; Disease Models, Animal; Fish Oils; Malaria, Cerebral; Male; Mice; Mice, Inbred CBA; Oxidative Stress; Phenylenediamines; Plasmodium berghei; Probucol; Vitamin E; Vitamin E Deficiency | 1995 |
Treatment of cholesterol-fed rabbits with dietary vitamins E and C inhibits lipoprotein oxidation but not development of atherosclerosis.
Topics: Animals; Arteriosclerosis; Ascorbic Acid; Cholesterol, Dietary; Drug Interactions; Lipoproteins; Oxidation-Reduction; Probucol; Rabbits; Vitamin E | 1994 |
Comparison of effects of probucol versus vitamin E on ex vivo oxidation susceptibility of lipoproteins in hyperlipoproteinemia.
Topics: Antioxidants; Cholesterol, LDL; Cholesterol, VLDL; Female; Humans; Hyperlipoproteinemias; Lipoproteins; Male; Oxidation-Reduction; Probucol; Vitamin E | 1994 |
Differing effects of probucol and vitamin E on the oxidation of lipoproteins, ceroid accumulation and protein uptake by macrophages.
Topics: Animals; Biological Transport; Cells, Cultured; Ceroid; Dose-Response Relationship, Drug; Humans; Kinetics; Lipid Peroxidation; Lipoproteins; Lipoproteins, LDL; Macrophages, Peritoneal; Male; Mice; Mice, Inbred BALB C; Oxidation-Reduction; Probucol; Serum Albumin, Bovine; Vitamin E | 1994 |
The influence of magnesium-pyridoxal-5'-phosphate-glutamate in comparison with probucol, alpha-tocopherol and trolox on copper-induced oxidation of human low density lipoprotein in vitro.
Topics: Arteriosclerosis; Chromans; Copper; Fatty Acids; Glutamine; Humans; In Vitro Techniques; Lipoproteins, LDL; Oxidation-Reduction; Probucol; Pyridoxal Phosphate; Vitamin E | 1994 |
A simple luminescence method for detecting lipid peroxidation and antioxidant activity in vitro.
Topics: Antioxidants; Energy Transfer; Humans; Lipid Peroxidation; Liposomes; Luminescent Measurements; Methemoglobin; Oxygen Consumption; Probucol; Rose Bengal; Vitamin E | 1994 |
Comparative study on the effect of low-dose vitamin E and probucol on the susceptibility of LDL to oxidation and the progression of atherosclerosis in Watanabe heritable hyperlipidemic rabbits.
Topics: Animals; Aorta; Arteriosclerosis; Dose-Response Relationship, Drug; Hyperlipidemias; Lipid Peroxides; Lipoproteins, LDL; Oxidation-Reduction; Probucol; Rabbits; Vitamin E | 1994 |
Tyrosyl radical generated by myeloperoxidase is a physiological catalyst for the initiation of lipid peroxidation in low density lipoprotein.
Topics: Ascorbic Acid; Catalysis; Free Radicals; Humans; Lipid Peroxidation; Lipid Peroxides; Lipoproteins, LDL; Neutrophils; Oxidation-Reduction; Peroxidase; Probucol; Substrate Specificity; Tyrosine; Vitamin E | 1994 |
Protection of linoleic acid hydroperoxide-induced cytotoxicity by phenolic antioxidants.
Topics: Antioxidants; Butylated Hydroxytoluene; Cell Survival; Cells, Cultured; Chromans; Endothelium, Vascular; Free Radicals; Humans; Linoleic Acids; Lipid Peroxides; Phenols; Probucol; Structure-Activity Relationship; Vitamin E | 1994 |
In vitro and in vivo inhibition of microsomal lipid peroxidation by MA-631.
Topics: Animals; Ascorbic Acid; Free Radicals; In Vitro Techniques; Lipid Peroxidation; Male; Medicine, Ayurvedic; Microsomes; NADP; Probucol; Rats; Rats, Sprague-Dawley; Thiobarbituric Acid Reactive Substances; Vitamin E | 1994 |
Ameliorative effect of dietary probucol on polychlorinated biphenyls-induced hypercholesterolemia and lipid peroxidation in the rat.
Topics: Animals; Cholesterol; Cholesterol, HDL; Diet; Hypercholesterolemia; Lipid Peroxidation; Liver; Male; Microsomes, Liver; Mitochondria, Liver; Polychlorinated Biphenyls; Probucol; Rats; Rats, Wistar; Thiobarbituric Acid Reactive Substances; Vitamin E | 1994 |
S 12340: a potent inhibitor of the oxidative modification of low-density lipoprotein in vitro and ex vivo in WHHL rabbits.
Topics: Animals; Antioxidants; Cells, Cultured; Copper; Endothelium, Vascular; Lipoproteins, LDL; Oxidation-Reduction; Probucol; Rabbits; Spiro Compounds; Vitamin E | 1994 |
Influence of probucol on enhanced LDL oxidation after fish oil treatment of hypertriglyceridemic patients.
Topics: Adult; Antioxidants; Cholesterol, HDL; Cholesterol, VLDL; Copper; Fish Oils; Humans; Hyperlipoproteinemia Type III; Hyperlipoproteinemia Type IV; Lipid Peroxidation; Lipoproteins, LDL; Lipoproteins, VLDL; Male; Middle Aged; Probucol; Thiobarbituric Acid Reactive Substances; Triglycerides; Vitamin E | 1993 |
Indications for the presence of circulating peroxidized low density lipoproteins in WHHL rabbits treated with antioxidants.
Topics: Animals; Antioxidants; Apolipoprotein B-100; Apolipoproteins B; Hyperlipidemias; Lipid Peroxidation; Lipids; Lipoproteins, LDL; Malondialdehyde; Molecular Weight; Probucol; Rabbits; Vitamin E | 1993 |
[Probucol and alpha-tocopherol stimulate the synthesis of bile acids in cultured rabbit hepatocytes].
Topics: Animals; Bile Acids and Salts; Cells, Cultured; Cholesterol; Lipoproteins, HDL; Liver; Male; Probucol; Rabbits; Vitamin E | 1993 |
Effect of the antioxidant probucol on transplant arteriosclerosis in aorta-allografted rabbits.
Topics: Animals; Antioxidants; Aorta, Abdominal; Aorta, Thoracic; Arteriosclerosis; Cholesterol; Cholesterol, Dietary; Cholesterol, HDL; Cholesterol, LDL; Cholesterol, VLDL; Humans; Lipoproteins; Male; Probucol; Rabbits; Time Factors; Transplantation, Heterotopic; Transplantation, Homologous; Triglycerides; Vitamin A; Vitamin E | 1995 |
Receptor-mediated endothelial cell dysfunction in diabetic vasculopathy. Soluble receptor for advanced glycation end products blocks hyperpermeability in diabetic rats.
Topics: Adult; Albumins; Animals; Antioxidants; Capillary Permeability; Cattle; Cells, Cultured; Diabetes Mellitus; Diabetes Mellitus, Experimental; Endothelium, Vascular; Erythrocyte Transfusion; Erythrocytes; Glycation End Products, Advanced; Humans; Inulin; Middle Aged; Probucol; Rats; Receptor for Advanced Glycation End Products; Receptors, Immunologic; Solubility; Vitamin E | 1996 |
Structure-function relationships of calcium antagonists. Effect on oxidative modification of low density lipoprotein.
Topics: Animals; Antioxidants; Calcium Channel Blockers; Cell Line; Dose-Response Relationship, Drug; Humans; Lipoproteins, LDL; Mice; Oxidation-Reduction; Probucol; Structure-Activity Relationship; Thiobarbituric Acid Reactive Substances; Vitamin E | 1996 |
Efficacy of hypochlorous acid scavengers in the prevention of protein carbonyl formation.
Topics: Animals; Antioxidants; Ascorbic Acid; Cattle; Cysteine; Free Radical Scavengers; Glutathione; Hypochlorous Acid; Kinetics; Oxidation-Reduction; Probucol; Serum Albumin, Bovine; Thioctic Acid; Uric Acid; Vitamin E | 1996 |
Effect of probucol, an oral hypocholesterolaemic agent, on acute tobacco smoke inhalation in rats.
Topics: Animals; Anticholesteremic Agents; Bronchoalveolar Lavage Fluid; Ceruloplasmin; Glutathione; Lung; Male; Oxidative Stress; Pancreatic Elastase; Peroxides; Probucol; Rats; Rats, Sprague-Dawley; Smoking; Specific Pathogen-Free Organisms; Vitamin E | 1996 |
Quenching of reactive oxidative species by probucol and comparison with other antioxidants.
Topics: Acetylcysteine; Antimutagenic Agents; Antioxidants; Ascorbic Acid; Benzophenones; Benzoquinones; Free Radicals; Oxidation-Reduction; Photolysis; Probucol; Reactive Oxygen Species; Spectrophotometry; Spectrum Analysis, Raman; Thioctic Acid; Vitamin E | 1996 |
Oxidation of low-density lipoprotein by human monocyte-macrophages results in toxicity to the oxidising culture.
Topics: Antioxidants; Coculture Techniques; Evaluation Studies as Topic; Humans; Kinetics; Lipoproteins, LDL; Macrophages; Monocytes; Oxidation-Reduction; Probucol; Vitamin E | 1996 |
Toxicity of oxidized low density lipoproteins for vascular smooth muscle cells and partial protection by antioxidants.
Topics: Animals; Antioxidants; Aorta; Butylated Hydroxytoluene; Cell Death; Cells, Cultured; Copper; Culture Media; Deferoxamine; Enzyme Inhibitors; Hydroxycholesterols; Hydroxymethylglutaryl CoA Reductases; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Ketocholesterols; Lipid Peroxidation; Lipoproteins, LDL; Lovastatin; Mevalonic Acid; Muscle, Smooth, Vascular; Oxidation-Reduction; Probucol; Swine; Thiobarbituric Acid Reactive Substances; Vitamin E | 1995 |
The resistance of low density lipoprotein to oxidation promoted by copper and its use as an index of antioxidant therapy.
Topics: Administration, Oral; Animals; Antioxidants; Aortic Diseases; Arteriosclerosis; Blood; Copper; Disease Models, Animal; Humans; Lipoproteins, LDL; Oxidation-Reduction; Probucol; Rabbits; Vitamin E | 1996 |
Oxidative modification of low-density lipoprotein by the human hepatoma cell line HepG2.
Topics: Antioxidants; Butylated Hydroxytoluene; Chromatography, Ion Exchange; Electrophoresis, Agar Gel; Electrophoresis, Polyacrylamide Gel; Hepatoblastoma; Humans; Lipid Peroxidation; Lipoproteins, LDL; Liver Neoplasms; Oxidation-Reduction; Probucol; Superoxides; Thiobarbituric Acid Reactive Substances; Tumor Cells, Cultured; Vitamin E | 1996 |
Influence of native and modified lipoproteins on migration of mouse peritoneal macrophages and the effect of the antioxidants vitamin E and Probucol.
Topics: Animals; Cell Movement; Cholesterol; Cholesterol Esters; Chromatography, High Pressure Liquid; Dose-Response Relationship, Drug; Female; Lipoproteins; Lipoproteins, LDL; Macrophages, Peritoneal; Mice; Mice, Inbred Strains; Probucol; Time Factors; Vitamin E | 1996 |
Effect of antioxidants alone and in combination with monounsaturated fatty acid-enriched diets on lipoprotein oxidation.
Topics: Adult; Aged; Antioxidants; Diabetes Mellitus, Type 2; Diet; Drug Interactions; Fatty Acids, Monounsaturated; Female; Humans; Lipid Peroxidation; Lipoproteins, LDL; Male; Middle Aged; Probucol; Vitamin E | 1996 |
Dietary antioxidant inhibits lipoprotein oxidation and renal injury in experimental focal segmental glomerulosclerosis.
Topics: Animals; Anticholesteremic Agents; Antioxidants; Cholesterol, Dietary; Diet; Glomerulosclerosis, Focal Segmental; Hypercholesterolemia; Immunohistochemistry; Kidney; Kidney Cortex; Lipid Peroxidation; Lipoproteins; Lipoproteins, LDL; Lipoproteins, VLDL; Male; Oxidation-Reduction; Probucol; Proteinuria; Puromycin Aminonucleoside; Rats; Rats, Sprague-Dawley; Vitamin E | 1997 |
Antioxidants prevent high-D-glucose-enhanced endothelial Ca2+/cGMP response by scavenging superoxide anions.
Topics: Animals; Antioxidants; Ascorbic Acid; Calcium; Cells, Cultured; Cyclic GMP; Cytosol; Endothelium, Vascular; Free Radical Scavengers; Glucose; Glutathione; Hypolipidemic Agents; Nitric Oxide; Probucol; Superoxides; Swine; Vitamin E | 1997 |
Oxidized lipoproteins found in patients with NIDDM stimulate radical-induced monocyte chemoattractant protein-1 mRNA expression in cultured human endothelial cells.
Topics: Antioxidants; Cells, Cultured; Chemokine CCL2; Deferoxamine; Diabetes Mellitus, Type 2; Endothelium, Vascular; Female; Humans; Lipoproteins; Male; Middle Aged; Oxidation-Reduction; Probucol; Reference Values; Regression Analysis; RNA, Messenger; Transcription, Genetic; Umbilical Veins; Vitamin E | 1997 |
Oxidant stress-induced transendothelial migration of monocytes is linked to phosphorylation of PECAM-1.
Topics: Adenine; Antibodies, Monoclonal; Antioxidants; Cells, Cultured; Chemotaxis, Leukocyte; Endothelium, Vascular; Enzyme Inhibitors; HL-60 Cells; Humans; Indoles; Kainic Acid; Kinetics; Maleimides; Marine Toxins; Monocytes; Oxazoles; Oxidative Stress; Peroxides; Phosphorylation; Platelet Endothelial Cell Adhesion Molecule-1; Probucol; Reactive Oxygen Species; Signal Transduction; tert-Butylhydroperoxide; Thiobarbituric Acid Reactive Substances; Umbilical Veins; Vitamin E | 1997 |
Effects of antioxidants on the oxidative susceptibility of low-density lipoprotein.
Topics: Adult; Antioxidants; Ascorbic Acid; Azo Compounds; Humans; Lipid Peroxidation; Lipoproteins, LDL; Nitriles; Oxidants; Probucol; Uric Acid; Vitamin E | 1997 |
Effect of vitamin E and probucol on dietary cholesterol-induced atherosclerosis in rabbits.
Topics: Animals; Anticholesteremic Agents; Aorta; Arteriosclerosis; Cholesterol; Cholesterol, Dietary; Endothelium, Vascular; Male; Microscopy, Electron, Scanning; Muscle, Smooth, Vascular; Probucol; Protein Kinase C; Rabbits; Vitamin E | 1998 |
Extent of antioxidant protection of plasma LDL is not a predictor of the antiatherogenic effect of antioxidants.
Topics: Animals; Antioxidants; Arteriosclerosis; Body Weight; Cholesterol; Lipid Peroxidation; Lipoproteins, LDL; Phenols; Probucol; Rabbits; Receptors, LDL; Statistics as Topic; Time Factors; Triglycerides; Vitamin E | 1997 |
Increase of vitamin E content in LDL and reduction of atherosclerosis in cholesterol-fed rabbits by a water-soluble antioxidant-rich fraction of Salvia miltiorrhiza.
Topics: Animals; Anticholesteremic Agents; Antioxidants; Aorta; Arteriosclerosis; Bepridil; Biphenyl Compounds; Cholesterol; Cholesterol, Dietary; Drugs, Chinese Herbal; Endothelium, Vascular; Free Radical Scavengers; Lipoproteins, LDL; Male; Oxidation-Reduction; Picrates; Probucol; Rabbits; Solubility; Vitamin E; Water | 1998 |
Some natural and synthetic antioxidants as stabilizers of beta-carotene conversion into vitamin A.
Topics: Animals; Antioxidants; Ascorbic Acid; beta Carotene; beta-Carotene 15,15'-Monooxygenase; Butylated Hydroxytoluene; Dietary Supplements; Drug Stability; Intestinal Mucosa; Oxygen; Oxygenases; Probucol; Quercetin; Rabbits; Rats; Rats, Wistar; Vitamin A; Vitamin E | 1998 |
Failure of antioxidant therapy to attenuate interstitial disease in rats with reversible nephrotic syndrome.
Topics: Animals; Anticholesteremic Agents; Antioxidants; Cholesterol; Collagen; Female; Fibronectins; Fibrosis; Kidney; Lipid Peroxides; Lipoproteins, LDL; Liver; Lovastatin; Macrophages; Microscopy, Fluorescence; Nephrotic Syndrome; Organ Size; Probucol; Proteinuria; Puromycin Aminonucleoside; Rats; Rats, Sprague-Dawley; Time Factors; Transforming Growth Factor beta; Treatment Failure; Vitamin E | 1998 |
Effect of probucol on LDL oxidation and atherosclerosis in LDL receptor-deficient mice.
Topics: Animals; Anticholesteremic Agents; Arteriosclerosis; Cholesterol, Dietary; Female; Lipoproteins, HDL; Lipoproteins, LDL; Male; Mice; Mice, Inbred C57BL; Probucol; Receptors, LDL; Vitamin E | 1998 |
Chain-breaking antioxidants and ferriheme-bound drugs are synergistic inhibitors of erythrocyte membrane peroxidation.
Topics: Adult; Amidines; Antioxidants; Ascorbic Acid; Chloroquine; Deferoxamine; Drug Synergism; Erythrocyte Membrane; Fatty Acids; Female; Hemin; Humans; Linoleic Acid; Lipid Peroxidation; Male; Membrane Lipids; Oxidation-Reduction; Oxygen Consumption; Oxyhemoglobins; Probucol; Pyridines; Reperfusion Injury; Vitamin E | 1998 |
Protective effect of a vitamin E analog, phosphatidylchromanol, against oxidative hemolysis of human erythrocytes.
Topics: Amidines; Antioxidants; Butylated Hydroxytoluene; Chromans; Erythrocyte Membrane; Erythrocytes; Free Radicals; Glycerophospholipids; Hemolysis; Humans; In Vitro Techniques; Oxidants; Oxidation-Reduction; Phosphatidic Acids; Probucol; Vitamin E | 1998 |
Measurement of reactive oxygen species by chemiluminescence in diet-induced atherosclerosis: protective roles of vitamin E and probucol on different radical species.
Topics: Animals; Aorta; Arteriosclerosis; Cholesterol; Cholesterol, Dietary; Luminescent Measurements; Male; Peroxidase; Probucol; Rabbits; Reactive Oxygen Species; Vitamin E | 1998 |
Vitamin E combined with selenium inhibits atherosclerosis in hypercholesterolemic rabbits independently of effects on plasma cholesterol concentrations.
Topics: Animals; Aorta; Arteriosclerosis; Ascorbic Acid; Cholesterol; Diet, Atherogenic; Drug Therapy, Combination; Lipids; Lipoproteins; Probucol; Rabbits; Selenium; Vitamin E | 1998 |
A simple luminescence method for detecting lipid peroxidation and antioxidant activity in vitro.
Topics: Animals; Antioxidants; In Vitro Techniques; Lipid Peroxidation; Liposomes; Luminescent Measurements; Methemoglobin; Microsomes, Liver; Oxygen Consumption; Probucol; Rats; Rose Bengal; Vitamin E | 1998 |
Antioxidant effect of probucol on RO2*/O2(*-)-induced peroxidation of human low-density lipoproteins.
Topics: Anticholesteremic Agents; Antioxidants; Ethanol; Free Radical Scavengers; Free Radicals; Gamma Rays; Humans; In Vitro Techniques; Kinetics; Lipid Peroxidation; Lipoproteins, LDL; Probucol; Radiochemistry; Solutions; Superoxides; Thiobarbituric Acid Reactive Substances; Vitamin E; Water | 1999 |
Antioxidants improve impaired insulin-mediated glucose uptake and prevent migration and proliferation of cultured rabbit coronary smooth muscle cells induced by high glucose.
Topics: Animals; Antioxidants; Becaplermin; Biological Transport, Active; Cell Cycle; Cell Division; Cell Movement; Cells, Cultured; Coronary Vessels; Enzyme Activation; Enzyme Inhibitors; Flow Cytometry; Fructose; Glucose; Insulin; Insulin Resistance; Muscle, Smooth, Vascular; NAD; Naphthalenes; Oxidation-Reduction; Oxidative Stress; Phospholipase D; Platelet-Derived Growth Factor; Probucol; Protein Kinase C; Proto-Oncogene Proteins c-sis; Rabbits; Suramin; Vitamin E | 1999 |
Antioxidant BO-653 and human macrophage-mediated LDL oxidation.
Topics: Antioxidants; Benzofurans; Cell Membrane Permeability; Cell Survival; Cells, Cultured; Cholesterol; Fatty Acids; Humans; Hydroxycholesterols; Lipid Peroxidation; Lipoproteins, LDL; Macrophages; Oxidation-Reduction; Oxidoreductases; Probucol; Vitamin E | 1999 |
Nitric oxide reduces the molecular activity of Na+,K+-ATPase in opossum kidney cells.
Topics: Animals; Anticholesteremic Agents; Antihypertensive Agents; Cells, Cultured; Cyclic GMP; Enzyme Inhibitors; Kidney Tubules, Proximal; Lipid Peroxidation; Nitric Oxide; Nitroprusside; Opossums; Ouabain; Probucol; Protein Binding; Signal Transduction; Sodium-Potassium-Exchanging ATPase; Vitamin E | 1999 |
Protective effects of vitamin e and probucol against gentamicin-induced nephrotoxicity in rats.
Topics: Acetylglucosaminidase; Animals; Anticholesteremic Agents; Creatinine; Drug Synergism; gamma-Glutamyltransferase; Gentamicins; Kidney; Kidney Diseases; Male; Malondialdehyde; Probucol; Rats; Rats, Sprague-Dawley; Sulfhydryl Compounds; Superoxide Dismutase; Urea; Vitamin E | 1999 |
Nitrogen dioxide radical generated by the myeloperoxidase-hydrogen peroxide-nitrite system promotes lipid peroxidation of low density lipoprotein.
Topics: Antioxidants; Arteriosclerosis; Ascorbic Acid; Free Radicals; HL-60 Cells; Humans; Hydrogen Peroxide; Lipid Peroxidation; Lipoproteins, LDL; Nitrites; Nitrogen Dioxide; Peroxidase; Probucol; Vitamin E | 1999 |
Inhibition of VCAM-1 expression in the arterial wall is shared by structurally different antioxidants that reduce early atherosclerosis in NZW rabbits.
Topics: Animals; Antioxidants; Aorta, Thoracic; Arteriosclerosis; Body Weight; Cholesterol, Dietary; Copper; Disease Models, Animal; Gene Expression Regulation; Hypercholesterolemia; Immunohistochemistry; Lipoproteins, LDL; Male; Oxidation-Reduction; Polymerase Chain Reaction; Probucol; Rabbits; Vascular Cell Adhesion Molecule-1; Vitamin E | 1999 |
d-Alpha-tocopherol prevents the hyperglycemia induced activation of diacylglycerol (DAG)-protein kinase C (PKC) pathway in vascular smooth muscle cell by an increase of DAG kinase activity.
Topics: Animals; Aorta, Abdominal; Aorta, Thoracic; Cells, Cultured; Diacylglycerol Kinase; Diglycerides; Glucose; Humans; Hyperglycemia; Isoenzymes; Kinetics; Muscle, Smooth, Vascular; Probucol; Rats; Rats, Sprague-Dawley; Vitamin E | 1999 |
Dynamics of action of bisphenol as radical-scavenging antioxidant against lipid peroxidation in solution and liposomal membranes.
Topics: Anticholesteremic Agents; Antioxidants; Benzhydryl Compounds; Bepridil; Biphenyl Compounds; Free Radical Scavengers; Lipid Peroxidation; Liposomes; Oxidation-Reduction; Phenols; Phenylenediamines; Picrates; Probucol; Solutions; Spin Labels; Vitamin E | 1999 |
The effect of vitamin E, probucol, and lovastatin on oxidative status and aortic fatty lesions in hyperlipidemic-diabetic hamsters.
Topics: Animals; Animals, Newborn; Anticholesteremic Agents; Antioxidants; Arteriosclerosis; Cells, Cultured; Cricetinae; Diabetes Mellitus, Experimental; Disease Models, Animal; Foam Cells; Hyperlipidemias; Lipid Peroxidation; Lovastatin; Male; Mesocricetus; Probucol; Reference Values; Streptozocin; Vitamin E | 2000 |
Antioxidative property of T-0970, a new ureidophenol derivative.
Topics: Alanine Transaminase; Animals; Antioxidants; Aspartate Aminotransferases; Brain; Butylated Hydroxytoluene; Ferric Compounds; Free Radical Scavengers; Hydroxyl Radical; Lipid Peroxidation; Male; Molecular Structure; Nitrilotriacetic Acid; Oxidative Stress; Phenols; Phenylurea Compounds; Probucol; Pyridines; Rats; Rats, Sprague-Dawley; Superoxides; Thiobarbituric Acid Reactive Substances; Urea; Vitamin E | 2000 |
Protective effect of phenolic antioxidants on the cytotoxicity induced by phosphatidylcholine hydroperoxide.
Topics: Antioxidants; Butylated Hydroxytoluene; Cell Survival; Cells, Cultured; Chromans; Endothelium, Vascular; Ethanol; Humans; Phosphatidylcholines; Probucol; Vitamin E | 2000 |
Effect of vitamin E on the development of atherosclerosis.
Topics: Animals; Anticholesteremic Agents; Arteriosclerosis; Cell Division; Cell Line; Cholesterol; Cholesterol, Dietary; Dose-Response Relationship, Drug; Male; Muscle, Smooth, Vascular; Probucol; Protein Kinase C; Rabbits; Vitamin E | 2000 |
Vitamin E and probucol reduce urinary lipophilic aldehydes and renal enlargement in streptozotocin-induced diabetic rats.
Topics: Aldehydes; Animals; Antioxidants; Ascorbic Acid; Blood Glucose; Diabetes Mellitus, Experimental; Diabetic Nephropathies; Feeding Behavior; Kidney; Male; Probucol; Rats; Rats, Wistar; Streptozocin; Vitamin E | 2000 |
The effect of pharmacological doses of different antioxidants on oxidation parameters and atherogenesis in hyperlipidaemic rabbits.
Topics: Administration, Oral; Animals; Anticholesteremic Agents; Antidotes; Antioxidants; Aorta; Arteriosclerosis; Diet; Dose-Response Relationship, Drug; Fatty Acids, Unsaturated; Hyperlipidemias; Lipoproteins; Oxidation-Reduction; Probucol; Rabbits; Tunica Intima; Ubiquinone; Vitamin E | 2001 |
Inhibitory effects of fluvastain and its metabolites on the formation of several reactive oxygen species.
Topics: Animals; Antioxidants; Fatty Acids, Monounsaturated; Fluvastatin; Free Radical Scavengers; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Indoles; Microsomes, Liver; Oxygen; Pravastatin; Probucol; Rats; Reactive Oxygen Species; Simvastatin; Singlet Oxygen; Vitamin E | 2001 |
Alpha-tocopherol and probucol reduce autoantibody titer to MDA-LDL in hypercholesterolemic rabbits.
Topics: alpha-Tocopherol; Animals; Anticholesteremic Agents; Antioxidants; Aorta; Arteriosclerosis; Autoantibodies; Cholesterol; Cholesterol, Dietary; Female; Hypercholesterolemia; Lipoproteins, LDL; Malondialdehyde; Probucol; Rabbits | 2001 |
Effects of insulin and antioxidant on plasma 8-hydroxyguanine and tissue 8-hydroxydeoxyguanosine in streptozotocin-induced diabetic rats.
Topics: 8-Hydroxy-2'-Deoxyguanosine; Animals; Antioxidants; Biomarkers; Blood Glucose; Deoxyguanosine; Diabetes Mellitus, Experimental; DNA Damage; Guanine; Insulin; Kidney; Liver; Male; Oxidative Stress; Probucol; Rats; Rats, Sprague-Dawley; Vitamin E | 2001 |
Comparison of antioxidant effects of naringin and probucol in cholesterol-fed rabbits.
Topics: Animals; Anticholesteremic Agents; Antioxidants; Cholesterol; Dietary Fats; Eating; Enzymes; Flavanones; Flavonoids; Gene Expression Regulation, Enzymologic; Hydrogen Peroxide; Lipid Peroxidation; Liver; Male; Organ Size; Probucol; Rabbits; Vitamin A; Vitamin E; Weight Gain | 2002 |
Inhibitory effect of a novel water-soluble vitamin E derivative on atherosclerosis in rabbits.
Topics: Administration, Oral; Animals; Antioxidants; Aorta; Arteriosclerosis; Aspartate Aminotransferases; Body Weight; Cholesterol, HDL; Cholesterol, LDL; Chromans; Disease Models, Animal; Dose-Response Relationship, Drug; Female; Glycosides; L-Lactate Dehydrogenase; Lipid Metabolism; Lipid Peroxidation; Male; Models, Cardiovascular; Oxidation-Reduction; Probucol; Rabbits; Solubility; Vitamin E | 2002 |
Comparison of the effects of alpha-tocopherol, ubiquinone-10 and probucol at therapeutic doses on atherosclerosis in WHHL rabbits.
Topics: alpha-Tocopherol; Animals; Antioxidants; Aorta; Arteriosclerosis; Coenzymes; Disease Models, Animal; Female; Humans; Lipids; Lipoproteins, LDL; Male; Probucol; Rabbits; Ubiquinone; Vitamin E | 2002 |
Ascorbic acid augments cytotoxicity induced by oxidized low-density lipoprotein.
Topics: alpha-Tocopherol; Animals; Antioxidants; Ascorbic Acid; Cattle; Cell Line; Cell Survival; Drug Synergism; In Vitro Techniques; Lipoproteins, LDL; Macrophages; Oxidation-Reduction; Probucol | 2003 |
Antioxidants decreases the intensification of low density lipoprotein in vivo peroxidation during therapy with statins.
Topics: Animals; Antioxidants; Arteriosclerosis; Coenzymes; Dose-Response Relationship, Drug; Double-Blind Method; Enzyme Inhibitors; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Lipid Peroxidation; Lipoproteins, LDL; Liver; Male; Middle Aged; Oxidation-Reduction; Pravastatin; Probucol; Pyridines; Rats; Time Factors; Ubiquinone; Vitamin E | 2003 |
Antioxidant role of human haptoglobin.
Topics: Animals; Antioxidants; CHO Cells; Copper; Cricetinae; Disulfides; Haptoglobins; Hemoglobins; Humans; Hydrogen Peroxide; Lipoproteins, LDL; Oxidants; Oxidation-Reduction; Oxidative Stress; Phenotype; Probucol; Protein Isoforms; Vitamin E | 2004 |
Vitamin E supplementation alters HDL-cholesterol concentration and paraoxonase activity in rabbits fed high-cholesterol diet: comparison with probucol.
Topics: Alanine Transaminase; Animals; Anticholesteremic Agents; Aorta; Aryldialkylphosphatase; Aspartate Aminotransferases; Base Sequence; Body Weight; Cholesterol, HDL; DNA Primers; Gene Expression; Liver; Male; Probucol; Rabbits; Vitamin E | 2005 |
Effects of alpha tocopherol and probucol supplements on allergen-induced airway inflammation and hyperresponsiveness in a mouse model of allergic asthma.
Topics: Acrolein; Allergens; alpha-Tocopherol; Animals; Antioxidants; Asthma; Bronchial Hyperreactivity; Bronchial Provocation Tests; Bronchoalveolar Lavage Fluid; Dietary Supplements; Dinoprost; Disease Models, Animal; Eosinophils; Female; Hypersensitivity; Immunoglobulin E; Interleukin-4; Interleukin-5; Mice; Mice, Inbred BALB C; Ovalbumin; Oxidative Stress; Probucol | 2006 |
Influence of aging on gastric ulcer healing activities of the antioxidants alpha-tocopherol and probucol.
Topics: Acetic Acid; Administration, Oral; Aging; alpha-Tocopherol; Animals; Anti-Ulcer Agents; Antioxidants; Disease Models, Animal; Lipid Peroxidation; Male; Probucol; Rats; Rats, Wistar; Stomach Ulcer; Superoxide Dismutase; Thiobarbituric Acid Reactive Substances | 2008 |
ATP-binding cassette transporter A1 is involved in hepatic alpha-tocopherol secretion.
Topics: alpha-Tocopherol; Animals; Anticholesteremic Agents; Apolipoprotein A-I; ATP Binding Cassette Transporter 1; ATP-Binding Cassette Transporters; Carrier Proteins; Cell Line, Tumor; Cholesterol; Dose-Response Relationship, Drug; Hepatocytes; Male; Mice; Mice, Inbred C57BL; Probucol; Rats; RNA Interference; RNA, Small Interfering; Time Factors | 2010 |
Inhibitory effects of clinical reagents having anti-oxidative activity on transforming growth factor-β1-induced expression of α-smooth muscle actin in human fetal lung fibroblasts.
Topics: Acetylcysteine; Actins; alpha-Tocopherol; Antioxidants; Cell Line; Fetus; Fibroblasts; Humans; Hypolipidemic Agents; Lovastatin; Lung; Phosphatidylcholines; Probucol; Reactive Oxygen Species; Superoxide Dismutase; Transforming Growth Factor beta1 | 2011 |
The antioxidant effect of β-caryophyllene protects rat liver from carbon tetrachloride-induced fibrosis by inhibiting hepatic stellate cell activation.
Topics: alpha-Tocopherol; Animals; Antioxidants; Arachidonate 5-Lipoxygenase; Carbon Tetrachloride Poisoning; Cell Line; Cell Survival; Dietary Supplements; Female; Flavoring Agents; Free Radical Scavengers; Hepatic Stellate Cells; Lipid Peroxidation; Lipoxygenase Inhibitors; Liver; Monocyclic Sesquiterpenes; Oxidative Stress; Polycyclic Sesquiterpenes; Probucol; Random Allocation; Rats; Rats, Wistar; Sesquiterpenes | 2013 |
A new function of Vitamin E-TPGS in the intestinal lymphatic transport of lipophilic drugs: enhancing the secretion of chylomicrons.
Topics: Animals; Biological Transport; Caco-2 Cells; Chylomicrons; Drug Carriers; Humans; Intestinal Mucosa; Intestines; Lymphatic Vessels; Male; Polyethylene Glycols; Probucol; Rats; Rats, Sprague-Dawley; Vitamin E | 2013 |
Directed self-assembled nanoparticles of probucol improve oral delivery: fabrication, performance and correlation.
Topics: Administration, Oral; Animals; Anticholesteremic Agents; Biological Availability; Caco-2 Cells; Drug Carriers; Humans; Male; Nanoparticles; Particle Size; Polyethylene Glycols; Polysorbates; Probucol; Rats, Sprague-Dawley; Surface-Active Agents; Vitamin E | 2014 |
Using in situ Raman spectroscopy to study the drug precipitation inhibition and supersaturation mechanism of Vitamin E TPGS from self-emulsifying drug delivery systems (SEDDS).
Topics: Anti-Inflammatory Agents, Non-Steroidal; Anticholesteremic Agents; Drug Carriers; Drug Delivery Systems; Emulsions; Hydrogen Bonding; Indomethacin; Kinetics; Polyethylene Glycols; Probucol; Spectrum Analysis, Raman; Vitamin E | 2015 |
Probucol-Induced α-Tocopherol Deficiency Protects Mice against Malaria Infection.
Topics: alpha-Tocopherol; Animals; Antimalarials; Antioxidants; Artemisinins; Drug Administration Schedule; Drug Synergism; Drug Therapy, Combination; Female; Lipid Peroxidation; Malaria; Male; Mice; Mice, Inbred C57BL; Oxidative Stress; Parasitemia; Plasmodium berghei; Plasmodium yoelii; Probucol; Survival Analysis | 2015 |
Effect of anti-hyperlipidemia drugs on the alpha-tocopherol concentration and their potential for murine malaria infection.
Topics: alpha-Tocopherol; Animals; Anticholesteremic Agents; Antimalarials; Berberine; Cholestyramine Resin; Ezetimibe; Female; Malaria; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; Parasitemia; Plasmodium yoelii; Probucol; Specific Pathogen-Free Organisms; Vitamin E Deficiency | 2016 |
Comparison of the antioxidant effects of equine estrogens, red wine components, vitamin E, and probucol on low-density lipoprotein oxidation in postmenopausal women.
Topics: Analysis of Variance; Antioxidants; Cardiovascular Diseases; Chromans; Estrogens; Estrogens, Conjugated (USP); Female; Hormone Replacement Therapy; Humans; Lipoproteins, LDL; Medroxyprogesterone Acetate; Middle Aged; Oxidation-Reduction; Postmenopause; Probucol; Progestins; Quercetin; Resveratrol; Thiobarbituric Acid Reactive Substances; Treatment Outcome; Vitamin E; Wine | 2018 |