d-alpha tocopherol has been researched along with methotrexate in 22 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 4 (18.18) | 18.2507 |
| 2000's | 2 (9.09) | 29.6817 |
| 2010's | 12 (54.55) | 24.3611 |
| 2020's | 4 (18.18) | 2.80 |
| Authors | Studies |
|---|---|
| Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A | 1 |
| Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K | 1 |
| Kouri, M; Kuitunen, T; Nyandoto, P; Pyrhönen, S | 1 |
| Anderson, R; Van Rensburg, CE; Van Staden, AM | 1 |
| Shyamala Devi, CS; Subramaniam, S | 1 |
| ElAttar, TM; Virji, AS | 1 |
| el-Bassiouni, EA; Helmy, M; Helmy, MH; Shohayeb, M | 1 |
| Alleva, R; Benassi, MS; Borghi, B; Gellert, N; Neuzil, J; Pazzaglia, L; Picci, P; Tomasetti, M | 1 |
| Aronow, BJ; Gibson, G; Kim, J; Mason, E; Matigian, N; Nones, K; Tronc, G; Wells, C; Wolfinger, RD | 1 |
| Bhori, M; Malviya, A; Marar, T; Singh, K | 1 |
| Haddad, E; Hatami, A; Marcoux, D; McCuaig, CC; Piram, M; Powell, J; Saint-Cyr, C | 1 |
| Bayat, N; Bükücü, N; Sencar, L; Tarakçioğlu, M; Yüncü, M | 1 |
| Dhanahiranpruk, S; Junyaprasert, VB; Moongkarndi, P; Sripha, K; Suksiriworapong, J | 1 |
| Burcu, B; Kanter, M; Karabacak, R; Orhon, ZN; Yarali, O | 1 |
| Abedi, SM; Amirfakhrian, H; Azizi, S; Hosseinimehr, SJ; Sadeghi, H | 1 |
| Bordbar, M; Fattahi, M; Haghpanah, S; Honar, N; Shakibazad, N | 1 |
| Chen, YH; Hung, YT; Wei, CW; Yiang, GT; Yu, YL | 1 |
| Cavaco-Paulo, A; Cerqueira, P; Guimarães, D; Loureiro, A; Moura, S; Noro, J; Silva, C | 1 |
| Ding, C; Gao, J; Kong, Y; Qin, Y; Wu, D; Wu, H; Yin, ZZ | 1 |
| Alwaseem, H; Birsoy, K; Garcia-Bermudez, J; La, K; Molina, H; Pratt, DA; Soula, M; Weber, RA; Yen, F; Zilka, O | 1 |
| Abdelbaky, FAF; Abdelzaher, WY; Alzahrani, KJ; Batiha, GE; Elbassuoni, E; Hafez, SMNA; Welson, NN | 1 |
| Ahmadi, H; Akbari, ME; Barati, M; Davoodi, SH; Jabbari, M; Khaki Bakhtiarvand, V; Nikmehr, P; Shabani, M | 1 |
1 review(s) available for d-alpha tocopherol and methotrexate
| Article | Year |
|---|---|
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk | 2016 |
3 trial(s) available for d-alpha tocopherol and methotrexate
| Article | Year |
|---|---|
Randomised comparison of fluorouracil, epidoxorubicin and methotrexate (FEMTX) plus supportive care with supportive care alone in patients with non-resectable gastric cancer.
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Combined Modality Therapy; Drug Administration Schedule; Epirubicin; Female; Fluorouracil; Humans; Male; Methotrexate; Middle Aged; Neoplasm Metastasis; Palliative Care; Stomach Neoplasms; Vitamin A; Vitamin E | 1995 |
Antioxidants as adjuvant therapy in rheumatoid disease. A preliminary study.
Topics: Adult; Anti-Inflammatory Agents, Non-Steroidal; Antioxidants; Antirheumatic Agents; Arthritis, Rheumatoid; Biomarkers; Drug Therapy, Combination; Female; Humans; Indomethacin; Male; Methotrexate; Middle Aged; Sulfasalazine; Vitamin E | 2001 |
Effect of ursodeoxycholic acid and vitamin E in the prevention of liver injury from methotrexate in pediatric leukemia.
Topics: Adolescent; Antimetabolites, Antineoplastic; Chemical and Drug Induced Liver Injury; Child; Child, Preschool; Cholagogues and Choleretics; Female; Humans; Liver; Liver Function Tests; Male; Methotrexate; Precursor B-Cell Lymphoblastic Leukemia-Lymphoma; Treatment Outcome; Ursodeoxycholic Acid; Vitamin E; Vitamins | 2018 |
18 other study(ies) available for d-alpha tocopherol and methotrexate
| Article | Year |
|---|---|
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship | 2010 |
The riminophenazine agents clofazimine and B669 inhibit the proliferation of cancer cell lines in vitro by phospholipase A2-mediated oxidative and nonoxidative mechanisms.
Topics: Animals; Arachidonic Acid; Bleomycin; Cell Death; Cell Division; Cisplatin; Clofazimine; Cyclooxygenase Inhibitors; Cytotoxicity, Immunologic; Growth Inhibitors; Humans; In Vitro Techniques; L-Lactate Dehydrogenase; Lipoxygenase Inhibitors; Lysophosphatidylcholines; Methotrexate; Neutrophils; Oxidation-Reduction; Phospholipases A; Phospholipases A2; Protein Kinase C; Tumor Cells, Cultured; Vitamin E | 1993 |
Vitamin E protects intestinal basolateral membrane from CMF-induced damages in rat.
Topics: Animals; Antineoplastic Combined Chemotherapy Protocols; Cyclophosphamide; Fluorouracil; Intestinal Mucosa; Lipid Metabolism; Lipid Peroxides; Male; Membranes; Methotrexate; Rats; Rats, Wistar; Thyrotropin; Vitamin E | 1995 |
Inhibition of growth in oral squamous carcinoma cells by cyclopentenone prostaglandins: comparison with chemotherapeutic agents.
Topics: Antineoplastic Agents; Carcinoma, Squamous Cell; Cell Division; Dinoprostone; Fluorouracil; Humans; Methotrexate; Mouth Neoplasms; Prostaglandin D2; Prostaglandins A; Prostaglandins A, Synthetic; Prostaglandins, Synthetic; Tocopherols; Tumor Cells, Cultured; Vitamin E | 1997 |
Alpha-tocopheryl succinate alters cell cycle distribution sensitising human osteosarcoma cells to methotrexate-induced apoptosis.
Topics: Apoptosis; Bone Neoplasms; Cell Cycle; Cell Line, Tumor; Cell Proliferation; Humans; Methotrexate; Osteosarcoma; Tocopherols; Vitamin E | 2006 |
Maternal influences on the transmission of leukocyte gene expression profiles in population samples from Brisbane, Australia.
Topics: Australia; Body Mass Index; CD4-Positive T-Lymphocytes; CD8-Positive T-Lymphocytes; Diabetes, Gestational; False Positive Reactions; Female; Gene Expression Profiling; Gene Expression Regulation; Humans; Leukocytes; Maternal Exposure; Methotrexate; Obesity; Pregnancy; Pregnancy Complications; Vitamin E | 2010 |
An in vitro study of the ameliorative role of α-tocopherol on methotrexate-induced oxidative stress in rat heart mitochondria.
Topics: Animals; Calcium; Calcium-Transporting ATPases; Methotrexate; Mitochondria, Heart; Mitochondrial Membrane Transport Proteins; Mitochondrial Permeability Transition Pore; Oxidative Stress; Rats; Rats, Wistar; Vitamin E | 2012 |
Short- and long-term outcome of linear morphoea in children.
Topics: Adolescent; Adrenal Cortex Hormones; Age of Onset; Aminoquinolines; Calcitriol; Child; Dermatologic Agents; Drug Therapy, Combination; Female; Humans; Imiquimod; Male; Methotrexate; Ointments; Phototherapy; Retrospective Studies; Scleroderma, Localized; Tacrolimus; Treatment Outcome; Vitamin A; Vitamin E | 2013 |
The effect of vitamin E and L-carnitine against methotrexate-induced injury in rat testis.
Topics: Analysis of Variance; Animals; Antioxidants; Carnitine; Male; Malondialdehyde; Methotrexate; Rats; Rats, Wistar; Superoxide Dismutase; Testicular Diseases; Vitamin B Complex; Vitamin E; Weight Loss | 2015 |
Enhanced toxicity and cellular uptake of methotrexate-conjugated nanoparticles in folate receptor-positive cancer cells by decorating with folic acid-conjugated d-α-tocopheryl polyethylene glycol 1000 succinate.
Topics: Breast Neoplasms; Female; Folic Acid; Humans; MCF-7 Cells; Methotrexate; Microscopy, Electron, Scanning; Nanoparticles; Polyethylene Glycols; Spectroscopy, Fourier Transform Infrared; Toxicokinetics; Vitamin E | 2015 |
Protective Effects of Vitamin E on Methotrexate-Induced Jejunal Mucosal Damage in Rats.
Topics: Animals; Antioxidants; Biomarkers; Cytoprotection; Disease Models, Animal; Gastrointestinal Hemorrhage; Glutathione Peroxidase; Intestinal Mucosa; Jejunal Diseases; Jejunum; Male; Malondialdehyde; Methotrexate; Necrosis; NF-kappa B; Nitric Oxide Synthase Type II; Oxidative Stress; Rats, Wistar; Superoxide Dismutase; Time Factors; Vitamin E | 2016 |
The use of 99mTc-phytate for assessment the protective effect of vitamin E against hepatotoxicity induced by methotrexat in rat.
Topics: Animals; Biological Transport; Cytoprotection; Liver; Methotrexate; Organotechnetium Compounds; Phytic Acid; Rats; Rats, Wistar; Spleen; Vitamin E | 2018 |
Anticancer effects of methotrexate in combination with α‑tocopherol and α‑tocopherol succinate on triple‑negative breast cancer.
Topics: alpha-Tocopherol; Antineoplastic Combined Chemotherapy Protocols; Apoptosis; Cell Line, Tumor; Cell Proliferation; Cell Survival; Dose-Response Relationship, Drug; Drug Screening Assays, Antitumor; Drug Synergism; Female; Humans; Methotrexate; Triple Negative Breast Neoplasms | 2019 |
PTS micelles for the delivery of hydrophobic methotrexate.
Topics: alpha-Tocopherol; Cell Line; Cell Survival; Drug Carriers; Humans; Hydrophobic and Hydrophilic Interactions; Methotrexate; Micelles | 2019 |
Disulfide-cleavage- and pH-triggered drug delivery based on a vesicle structured amphiphilic self-assembly.
Topics: Acrylic Resins; alpha-Tocopherol; Cell Survival; Cystamine; Disulfides; Drug Delivery Systems; Hep G2 Cells; Humans; Hydrogen Bonding; Hydrogen-Ion Concentration; Hydrophobic and Hydrophilic Interactions; Magnetic Resonance Spectroscopy; Methotrexate; Microscopy, Electron, Transmission; Spectroscopy, Fourier Transform Infrared | 2020 |
Metabolic determinants of cancer cell sensitivity to canonical ferroptosis inducers.
Topics: Antineoplastic Agents; Antioxidants; Biopterins; Carbolines; Cell Line, Tumor; Cell Proliferation; Cystine; Dose-Response Relationship, Drug; Ferroptosis; Folic Acid Antagonists; Gene Expression Profiling; Gene Expression Regulation, Neoplastic; Humans; Jurkat Cells; Lipid Peroxidation; Methotrexate; Oxidative Stress; Phospholipid Hydroperoxide Glutathione Peroxidase; Piperazines; Reactive Oxygen Species; Signal Transduction; Tetrahydrofolate Dehydrogenase; Vitamin E | 2020 |
Efficacy of vitamin E in protection against methotrexate induced placental injury in albino rats.
Topics: Animals; Antioxidants; Chorion; Cyclooxygenase 2; Edema; Female; Free Radical Scavengers; Immunohistochemistry; Methotrexate; Organ Size; Oxidative Stress; Placenta; Pregnancy; Rats; Trophoblasts; Vitamin E | 2021 |
Antioxidant nutrients can increase high-dose Methotrexate efficacy in 4T1 breast tumor Model: An experimental study on Vitamin E Succinate and Methyl-selenic acid.
Topics: alpha-Tocopherol; Animals; Antioxidants; Forkhead Transcription Factors; Methotrexate; Mice; Neoplasms; Nutrients; Selenic Acid; Vascular Endothelial Growth Factor A | 2022 |