Page last updated: 2024-08-21

d-alpha tocopherol and gentamicin

d-alpha tocopherol has been researched along with gentamicin in 25 studies

Research

Studies (25)

TimeframeStudies, this research(%)All Research%
pre-19901 (4.00)18.7374
1990's9 (36.00)18.2507
2000's9 (36.00)29.6817
2010's6 (24.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Yuan, F1
Ademuyiwa, O; Ngaha, EO; Ubah, FO1
Josepovitz, C; Kaloyanides, GJ; Lane, BP; Ling, KY; Ramsammy, LS1
Haber, C; Zurovsky, Y1
Fauconneau, B; Huguet, F; Piriou, A; Tallineau, C1
Maesaka, J; Schwob, N; Trachtman, H; Valderrama, E1
Canbolat, O; Durak, I; Ekinci, C; Gökhun, IH; Kavutcu, M; Olcay, E; Oztürk, S; Ulutepe, S1
Canbolat, O; Durak, I; Kaçmaz, M; Kavutcu, M; Oztürk, HS1
Dionyssiou-Asteriou, A; Giamarellos-Bourboulis, EJ; Giamarellou, H; Grecka, P1
Abdel-Naim, AB; Abdel-Wahab, MH; Attia, FF1
Dolay, K; Köksoy, F; Lice, H; Ozşeker, A; Soybir, G; Soybir, N1
Ferraresi, A; Fetoni, AR; Paludetti, G; Scarano, E; Sergi, B; Troiani, D1
Ferraresi, A; Fetoni, AR; Paludetti, G; Sergi, B; Troiani, D1
Azzena, GB; Ferraresi, A; Fetoni, AR; Maurizi, M; Paludetti, G; Sergi, B; Troiani, D1
Faghihi, M; Ghaznavi, R; Kadkhodaee, M; Khastar, H; Zahmatkesh, M1
Arab, HA; Ghaznavi, R; Kadkhodaee, M; Khastar, H; Mahdavi-Mazdeh, M; Zahmatkesh, M1
Davitashvili, O; Kevanishvili, Z; Kharkheli, E; Maglakelidze, T; Schacht, J1
Avizeh, R; Esmailzadeh, S; Givi, ME; Morovvati, H; Shahriari, A; Varzi, HN1
Arumugam, M; Kalayarasan, S; Manikandan, R; Prabhu, PN; Sriram, N; Sudhandiran, G1
Deshpande, S; Patel Manali, B; Shah, G1
Addai-Mensah, J; Losic, D; Sinn Aw, M1
Dong, C; Feng, Y; Liu, D; Liu, P; Lv, P; Wu, H; Wu, X; Zhou, Y1
DeRemer, SJ; Le Prell, CG; Miller, JM; Nelson, MA; Ojano-Dirain, C; Prieskorn, DM; Rudnick, EW1
Albert, AP; Babu, D; Barnwal, P; Das, S; Jothivel, N; Ramasamy, A; Swapna, A1
Ilic, S; Mladenovic, M; Stojiljkovic, N; Todorovic, J; Veljkovic, M1

Trials

2 trial(s) available for d-alpha tocopherol and gentamicin

ArticleYear
Does vitamin E prevent gentamicin-induced ototoxicity?
    Georgian medical news, 2007, Issue:146

    Topics: Adolescent; Adult; Aged; Anti-Bacterial Agents; Double-Blind Method; Female; Gentamicins; Hearing Loss; Humans; Male; Middle Aged; Placebos; Pneumonia, Bacterial; Vitamin E

2007
Effect of silymarin and vitamin E on gentamicin-induced nephrotoxicity in dogs.
    Journal of veterinary pharmacology and therapeutics, 2007, Volume: 30, Issue:5

    Topics: Animals; Anti-Bacterial Agents; Blood Urea Nitrogen; Creatinine; Dog Diseases; Dogs; Drug Therapy, Combination; Gentamicins; Injections, Intramuscular; Kidney Diseases; Malondialdehyde; Phytotherapy; Protective Agents; Silybum marianum; Silymarin; Vitamin E

2007

Other Studies

23 other study(ies) available for d-alpha tocopherol and gentamicin

ArticleYear
[The effects of free radicals in experimental gentamicin nephrotoxicity].
    Zhonghua yi xue za zhi, 1990, Volume: 70, Issue:2

    Topics: Animals; Blood Urea Nitrogen; Free Radicals; Gentamicins; Kidney; Kidney Diseases; Lipid Peroxides; Male; Rabbits; Superoxide Dismutase; Vitamin E

1990
Vitamin E and selenium in gentamicin nephrotoxicity.
    Human & experimental toxicology, 1990, Volume: 9, Issue:5

    Topics: Animals; Drug Synergism; Female; Gentamicins; Kidney; Membrane Lipids; Phospholipids; Proteins; Rats; Selenium; Vitamin E

1990
Failure of inhibition of lipid peroxidation by vitamin E to protect against gentamicin nephrotoxicity in the rat.
    Biochemical pharmacology, 1987, Jul-01, Volume: 36, Issue:13

    Topics: Animals; Arachidonic Acid; Arachidonic Acids; Catalase; Fatty Acids; Gentamicins; Glutathione; Kidney Cortex; Kidney Diseases; Kidney Tubules, Proximal; Lipid Peroxides; Male; Malondialdehyde; Phospholipids; Rats; Rats, Inbred Strains; Superoxide Dismutase; Vitamin E

1987
Antioxidants attenuate endotoxin-gentamicin induced acute renal failure in rats.
    Scandinavian journal of urology and nephrology, 1995, Volume: 29, Issue:2

    Topics: Animals; Antioxidants; Dose-Response Relationship, Drug; Endotoxins; Free Radical Scavengers; Gentamicins; Kidney; Kidney Failure, Chronic; Kidney Function Tests; Lipid Peroxidation; Male; Plant Extracts; Rats; Thiourea; Vitamin E

1995
Gentamicin-induced kidney damage and lipid peroxidation in rats.
    Toxicology letters, 1995, Volume: 76, Issue:2

    Topics: Animals; Fatty Acids; Gentamicins; In Vitro Techniques; Kidney; Kidney Diseases; Lipid Peroxidation; Rats; Rats, Sprague-Dawley; Thiobarbituric Acid Reactive Substances; Vitamin E

1995
Dietary vitamin E supplementation ameliorates renal injury in chronic puromycin aminonucleoside nephropathy.
    Journal of the American Society of Nephrology : JASN, 1995, Volume: 5, Issue:10

    Topics: Animals; Blood Pressure; Chronic Disease; Diet; Dose-Response Relationship, Drug; Gentamicins; Kidney; Kidney Diseases; Male; Proteinuria; Puromycin Aminonucleoside; Rats; Rats, Sprague-Dawley; Reference Values; Vitamin E

1995
Reduced enzymatic antioxidant defense mechanism in kidney tissues from gentamicin-treated guinea pigs: effects of vitamins E and C.
    Nephron, 1996, Volume: 72, Issue:2

    Topics: Animals; Antioxidants; Ascorbic Acid; Catalase; Drug Combinations; Free Radicals; Gentamicins; Glutathione Peroxidase; Guinea Pigs; Kidney; Male; Oxidoreductases; Protein Synthesis Inhibitors; Superoxide Dismutase; Vitamin E; Xanthine Oxidase

1996
The effects of gentamicin on the activities of glutathione peroxidase and superoxide dismutase enzymes and malondialdehyde levels in heart tissues of guinea pigs.
    Current medical research and opinion, 1997, Volume: 14, Issue:1

    Topics: Animals; Drug Interactions; Free Radicals; Gentamicins; Glutathione Peroxidase; Guinea Pigs; Heart; Humans; In Vitro Techniques; Male; Malondialdehyde; Myocardium; Superoxide Dismutase; Vitamin E

1997
In vitro activity of polyunsaturated fatty acids on Pseudomonas aeruginosa: relationship to lipid peroxidation.
    Prostaglandins, leukotrienes, and essential fatty acids, 1998, Volume: 58, Issue:4

    Topics: Amikacin; Ampicillin Resistance; Anti-Bacterial Agents; Arachidonic Acid; Ceftazidime; Cephalosporin Resistance; Cephalosporins; Colony Count, Microbial; Drug Resistance, Microbial; Drug Resistance, Multiple; Fatty Acids, Unsaturated; gamma-Linolenic Acid; Gentamicins; Imipenem; Lipid Peroxidation; Malondialdehyde; Microbial Sensitivity Tests; Penicillin Resistance; Penicillins; Piperacillin; Pseudomonas aeruginosa; Species Specificity; Thienamycins; Ticarcillin; Tobramycin; Vitamin E

1998
Protective effects of vitamin e and probucol against gentamicin-induced nephrotoxicity in rats.
    Pharmacological research, 1999, Volume: 40, Issue:2

    Topics: Acetylglucosaminidase; Animals; Anticholesteremic Agents; Creatinine; Drug Synergism; gamma-Glutamyltransferase; Gentamicins; Kidney; Kidney Diseases; Male; Malondialdehyde; Probucol; Rats; Rats, Sprague-Dawley; Sulfhydryl Compounds; Superoxide Dismutase; Urea; Vitamin E

1999
The effects of desferrioxamin and vitamin E as supplements to antibiotics in the treatment of peritonitis in rats.
    Journal of the Royal College of Surgeons of Edinburgh, 2002, Volume: 47, Issue:5

    Topics: Animals; Clindamycin; Deferoxamine; Drug Therapy, Combination; Gentamicins; Male; Peritonitis; Rats; Rats, Sprague-Dawley; Vitamin E

2002
Protective effects of alpha-tocopherol against gentamicin-induced Oto-vestibulo toxicity: an experimental study.
    Acta oto-laryngologica, 2003, Volume: 123, Issue:2

    Topics: alpha-Tocopherol; Animals; Auditory Threshold; Disease Models, Animal; Drug Interactions; Drug-Related Side Effects and Adverse Reactions; Ear, Inner; Evoked Potentials, Auditory, Brain Stem; Female; Gentamicins; Guinea Pigs; Hearing Loss; Male; Microscopy, Electron, Scanning; Probability; Reference Values; Reflex, Vestibulo-Ocular; Vestibule, Labyrinth

2003
alpha-Tocopherol protective effects on gentamicin ototoxicity: an experimental study.
    International journal of audiology, 2004, Volume: 43, Issue:3

    Topics: Action Potentials; alpha-Tocopherol; Analysis of Variance; Animals; Anti-Bacterial Agents; Antioxidants; Audiometry, Evoked Response; Cochlea; Electrophysiology; Gentamicins; Guinea Pigs; Hair Cells, Auditory, Outer; Hearing Loss; Microscopy, Electron, Scanning; Treatment Outcome

2004
The role of antioxidants in protection from ototoxic drugs.
    Acta oto-laryngologica. Supplementum, 2004, Issue:552

    Topics: Action Potentials; alpha-Tocopherol; Animals; Anti-Bacterial Agents; Antineoplastic Agents; Antioxidants; Audiometry, Evoked Response; Cisplatin; Cochlea; Female; Gentamicins; Guinea Pigs; Hearing Loss; Microscopy; Reflex, Vestibulo-Ocular; Tiopronin; Vestibule, Labyrinth

2004
Effects of co-supplementation of vitamins E and C on gentamicin-induced nephrotoxicity in rat.
    Experimental physiology, 2005, Volume: 90, Issue:4

    Topics: Acetylglucosamine; Acetylglucosaminidase; Alkaline Phosphatase; Animals; Anti-Bacterial Agents; Antioxidants; Ascorbic Acid; Gentamicins; Glomerular Filtration Rate; Glutathione; Histocytochemistry; In Vitro Techniques; Inulin; Kidney Diseases; L-Lactate Dehydrogenase; Male; Rats; Rats, Sprague-Dawley; Vitamin E

2005
Antioxidant vitamins preserve superoxide dismutase activities in gentamicin-induced nephrotoxicity.
    Transplantation proceedings, 2007, Volume: 39, Issue:4

    Topics: Animals; Antioxidants; Ascorbic Acid; Gentamicins; Kidney; Male; Models, Animal; Rats; Rats, Sprague-Dawley; Superoxide Dismutase; Vitamin E; Vitamins

2007
Diallyl sulfide enhances antioxidants and inhibits inflammation through the activation of Nrf2 against gentamicin-induced nephrotoxicity in Wistar rats.
    European journal of pharmacology, 2009, Mar-15, Volume: 606, Issue:1-3

    Topics: Allyl Compounds; Animals; Anti-Inflammatory Agents; Antioxidants; Ascorbic Acid; Biomarkers; Enzyme Induction; Gentamicins; Glutathione; Inflammation; Kidney; Kidney Glomerulus; Kidney Tubules; Lipid Peroxidation; Male; NF-E2-Related Factor 2; NF-kappa B; Nitric Oxide Synthase Type II; Oxidative Stress; Peroxidase; Rats; Rats, Wistar; Sulfides; Tumor Necrosis Factor-alpha; Vitamin E

2009
Evaluation of efficacy of vitamin E and N-acetyl cysteine in gentamicin-induced nephrotoxicity in rats.
    Renal failure, 2011, Volume: 33, Issue:3

    Topics: Acetylcysteine; Acute Kidney Injury; Animals; Anti-Bacterial Agents; Antioxidants; Drug Evaluation, Preclinical; Gentamicins; Male; Rats; Rats, Sprague-Dawley; Vitamin E

2011
Polymer micelles for delayed release of therapeutics from drug-releasing surfaces with nanotubular structures.
    Macromolecular bioscience, 2012, Volume: 12, Issue:8

    Topics: Delayed-Action Preparations; Drug Carriers; Drug Compounding; Electrochemical Techniques; Gentamicins; Hydrophobic and Hydrophilic Interactions; Indomethacin; Kinetics; Micelles; Microscopy, Electron, Scanning; Nanotubes; Poloxamer; Polyethylene Glycols; Propylene Glycols; Solubility; Succinates; Titanium; Vitamin E

2012
Study on therapeutic action of bone marrow derived mesenchymal stem cell combined with vitamin E against acute kidney injury in rats.
    Life sciences, 2013, May-02, Volume: 92, Issue:14-16

    Topics: Acute Kidney Injury; Animals; Antioxidants; Apoptosis; Blood Urea Nitrogen; Bone Marrow Cells; Cell Proliferation; Coculture Techniques; Combined Modality Therapy; Creatinine; Disease Models, Animal; Down-Regulation; Endoplasmic Reticulum; Gentamicins; Male; Mesenchymal Stem Cell Transplantation; Microscopy, Electron, Transmission; Rats; Rats, Wistar; Up-Regulation; Vitamin E

2013
Assessment of nutrient supplement to reduce gentamicin-induced ototoxicity.
    Journal of the Association for Research in Otolaryngology : JARO, 2014, Volume: 15, Issue:3

    Topics: Animals; Anti-Bacterial Agents; Ascorbic Acid; Bacteria; beta Carotene; Dietary Supplements; Evoked Potentials, Auditory, Brain Stem; Gentamicins; Guinea Pigs; Hair Cells, Auditory; Magnesium; Male; Vitamin E

2014
Evaluation of the Protective Role of Glycine max Seed Extract (Soybean Oil) in Drug-Induced Nephrotoxicity in Experimental Rats.
    Journal of dietary supplements, 2018, Sep-03, Volume: 15, Issue:5

    Topics: Animals; Antioxidants; Biomarkers; Gentamicins; Kidney; Kidney Diseases; Kidney Function Tests; Male; Rats; Rats, Sprague-Dawley; Rifampin; Soybean Oil; Vitamin E

2018
α-Tocopherol Reduces Morphological Changes and Oxidative Stress during Gentamicin-Induced Acute Renal Failure.
    Bulletin of experimental biology and medicine, 2018, Volume: 164, Issue:4

    Topics: Acute Kidney Injury; alpha-Tocopherol; Animals; Antioxidants; Catalase; Gentamicins; Kidney Glomerulus; Kidney Tubules; Malondialdehyde; Oxidative Stress; Rats; Rats, Wistar

2018