Page last updated: 2024-08-21

d-alpha tocopherol and etoposide

d-alpha tocopherol has been researched along with etoposide in 20 studies

Research

Studies (20)

TimeframeStudies, this research(%)All Research%
pre-19902 (10.00)18.7374
1990's2 (10.00)18.2507
2000's4 (20.00)29.6817
2010's10 (50.00)24.3611
2020's2 (10.00)2.80

Authors

AuthorsStudies
Gibbons, S; Kaatz, GW; Zloh, M1
Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A1
Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K1
Clemens, MR; Ehninger, G; Gey, KF; Ladner, C1
Bowman, WP; Brown, RE; Champion, JE; D'Cruz, CA; Pick, TE1
Kagan, VE; Tyurina, YY1
Borisenko, GG; Fabisiak, JP; Kagan, VE; Thampatty, P; Tyurin, VA; Tyurina, YY; Yalowich, JC1
Bergman, GF; Blumberg, JB; Carlson, JL; Furr, CE; Galloway, JR; Griffith, DP; Jonas, CR; Jones, DP; Puckett, AB; Szeszycki, EE; Tyre, C; Ziegler, TR1
Kang, YH; Kim, SH; Lee, E; Lee, HJ; Lim, SJ; Park, YG; Youk, HJ1
Kumagai, T; Miyoshi, N; Nakamura, Y; Naniwa, K; Osawa, T; Uchida, K1
Constantinou, AI; Constantinou, C; Hyatt, JA; Neophytou, CM; Papas, KA; Vraka, P1
Gogvadze, V; Kruspig, B; Zhivotovsky, B1
Al-Bader, MM; Khan, KM; Kilarkaje, N; Mousa, AM1
Al-Bader, M; Kilarkaje, N1
Dadashzadeh, S; Saadati, R1
Kilarkaje, N1
Bian, J; Cai, J; Luo, S; Tsend-Ayush, A; Wen, J; Yao, J; Yin, L; Yuan, Z; Zhou, J; Zhu, X1
Beig, A; Dahan, A; Fine-Shamir, N; Lindley, D; Miller, JM; Porat, D1
Beig, A; Dahan, A; Fine-Shamir, N1
Abou Najem, S; Fakhoury, R; Hodroj, MH; Idriss, M; Rizk, S; Younes, M1

Reviews

2 review(s) available for d-alpha tocopherol and etoposide

ArticleYear
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
    Drug discovery today, 2016, Volume: 21, Issue:4

    Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk

2016
Recycling and redox cycling of phenolic antioxidants.
    Annals of the New York Academy of Sciences, 1998, Nov-20, Volume: 854

    Topics: Animals; Antioxidants; Chromosome Aberrations; Coenzymes; DNA Damage; Etoposide; Humans; Models, Biological; Oxidation-Reduction; Oxidative Stress; Phenols; Ubiquinone; Vitamin E

1998

Trials

1 trial(s) available for d-alpha tocopherol and etoposide

ArticleYear
Plasma antioxidant status after high-dose chemotherapy: a randomized trial of parenteral nutrition in bone marrow transplantation patients.
    The American journal of clinical nutrition, 2000, Volume: 72, Issue:1

    Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; Antioxidants; Ascorbic Acid; Bone Marrow Neoplasms; Bone Marrow Transplantation; Busulfan; Cyclophosphamide; Etoposide; Female; Glutathione; Glutathione Peroxidase; Humans; Male; Middle Aged; Parenteral Nutrition, Total; Vitamin E; Zinc

2000

Other Studies

17 other study(ies) available for d-alpha tocopherol and etoposide

ArticleYear
Inhibitors of multidrug resistance (MDR) have affinity for MDR substrates.
    Bioorganic & medicinal chemistry letters, 2004, Feb-23, Volume: 14, Issue:4

    Topics: Anti-Bacterial Agents; Antineoplastic Agents; ATP Binding Cassette Transporter, Subfamily B; Biological Transport; Cell Membrane; Drug Resistance, Microbial; Drug Resistance, Multiple; Ligands; Models, Molecular

2004
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
    Chemical research in toxicology, 2010, Volume: 23, Issue:1

    Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship

2010
Effect of etoposide (VP16-213) on lipid peroxidation and antioxidant status in a high-dose radiochemotherapy regimen.
    Cancer chemotherapy and pharmacology, 1989, Volume: 25, Issue:3

    Topics: Anemia, Aplastic; Antioxidants; beta Carotene; Bone Marrow Transplantation; Carotenoids; Combined Modality Therapy; Etoposide; Humans; Leukemia; Lipid Peroxidation; Lipid Peroxides; Myelodysplastic Syndromes; Parenteral Nutrition; Radiotherapy Dosage; Time Factors; Vitamin E

1989
Endoperoxidation, hyperprostaglandinemia, and hyperlipidemia in a case of erythrophagocytic lymphohistiocytosis. Reversal with VP-16 and indomethacin.
    Cancer, 1987, Nov-15, Volume: 60, Issue:10

    Topics: Dinoprost; Dinoprostone; Etoposide; Glucose; Histiocytes; Humans; Hyperlipidemias; Indomethacin; Infant; Lipid Peroxides; Liver; Lymphatic Diseases; Lymphocytosis; Male; Phagocytosis; Prostaglandins E; Prostaglandins F; Vitamin E

1987
Mechanism-based chemopreventive strategies against etoposide-induced acute myeloid leukemia: free radical/antioxidant approach.
    Molecular pharmacology, 1999, Volume: 56, Issue:3

    Topics: Acute Disease; Antineoplastic Agents, Phytogenic; Antioxidants; Ascorbic Acid; Chromans; DNA Topoisomerases, Type II; DNA, Neoplasm; Electrons; Etoposide; Free Radicals; HL-60 Cells; Humans; Hydrogen Peroxide; Leukemia, Myeloid; Oxidation-Reduction; Peroxidase; Phospholipids; Sulfhydryl Compounds; Vitamin E

1999
Potentiation by alpha-tocopheryl succinate of the etoposide response in multidrug resistance protein 1-expressing glioblastoma cells.
    Cancer letters, 2005, Jan-20, Volume: 217, Issue:2

    Topics: Antineoplastic Agents, Phytogenic; ATP Binding Cassette Transporter, Subfamily B, Member 1; Cell Line, Tumor; Drug Synergism; Etoposide; Glioblastoma; Glutathione; Humans; Liposomes; Vitamin E

2005
Alpha-tocopherol-mediated caspase-3 up-regulation enhances susceptibility to apoptotic stimuli.
    Biochemical and biophysical research communications, 2005, Aug-26, Volume: 334, Issue:2

    Topics: alpha-Tocopherol; Apoptosis; Caspase 3; Caspases; Etoposide; fas Receptor; Humans; Hydrogen Peroxide; Immunoglobulins; Jurkat Cells; Receptors, Tumor Necrosis Factor; Up-Regulation

2005
Induction of DNA damage and caspase-independent programmed cell death by vitamin E.
    Nutrition and cancer, 2012, Volume: 64, Issue:1

    Topics: Apoptosis; Caspase 3; Caspases; Cell Line, Tumor; DNA Damage; Drug Screening Assays, Antitumor; Etoposide; Humans; Isomerism; Male; Poly(ADP-ribose) Polymerases; Polyethylene Glycols; Prostatic Neoplasms; Tocotrienols; Vitamin E

2012
Contrasting effects of α-tocopheryl succinate on cisplatin- and etoposide-induced apoptosis.
    Mitochondrion, 2013, Volume: 13, Issue:5

    Topics: alpha-Tocopherol; Antineoplastic Agents; Apoptosis; Cell Line; Cisplatin; Drug Interactions; Etoposide; Humans; Mitochondria

2013
Antioxidants enhance the recovery of three cycles of bleomycin, etoposide, and cisplatin-induced testicular dysfunction, pituitary-testicular axis, and fertility in rats.
    Fertility and sterility, 2013, Volume: 100, Issue:4

    Topics: alpha-Tocopherol; Animals; Antineoplastic Combined Chemotherapy Protocols; Antioxidants; Ascorbic Acid; Atrophy; Bleomycin; Blotting, Western; Cisplatin; Cytoprotection; Disease Models, Animal; Drug Combinations; Enzyme-Linked Immunosorbent Assay; Etoposide; Female; Fertility; Hormones; Immunohistochemistry; Male; Pituitary Gland; Proliferating Cell Nuclear Antigen; Rats; Rats, Sprague-Dawley; Recovery of Function; Selenium; Sperm Count; Sperm Motility; Spermatogenesis; Testicular Diseases; Testis; Time Factors; Transferrin; Zinc

2013
Effects of antioxidants on drugs used against testicular cancer-induced alterations in metastasis-associated protein 1 signaling in the rat testis.
    Toxicology and industrial health, 2016, Volume: 32, Issue:1

    Topics: Actins; alpha-Tocopherol; Animals; Antineoplastic Agents; Antioxidants; Apoptosis; Ascorbic Acid; Bleomycin; Cisplatin; Disease Models, Animal; DNA Damage; Dose-Response Relationship, Drug; Etoposide; Histone Deacetylases; Male; Proteins; Rats; Rats, Sprague-Dawley; Real-Time Polymerase Chain Reaction; Selenium; Signal Transduction; Testicular Neoplasms; Testis; Up-Regulation

2016
Marked effects of combined TPGS and PVA emulsifiers in the fabrication of etoposide-loaded PLGA-PEG nanoparticles: in vitro and in vivo evaluation.
    International journal of pharmaceutics, 2014, Apr-10, Volume: 464, Issue:1-2

    Topics: alpha-Tocopherol; Animals; Drug Evaluation, Preclinical; Emulsifying Agents; Etoposide; Male; Nanoparticles; Polyethylene Glycols; Polyglactin 910; Polyvinyl Alcohol; Rats; Rats, Wistar

2014
Effects of combined treatment of α-tocopherol, L-ascorbic acid, selenium and zinc on bleomycin, etoposide and cisplatin-induced alterations in testosterone synthesis pathway in rats.
    Cancer chemotherapy and pharmacology, 2014, Volume: 74, Issue:6

    Topics: alpha-Tocopherol; Animals; Antineoplastic Combined Chemotherapy Protocols; Antioxidants; Ascorbic Acid; Bleomycin; Blotting, Western; Cisplatin; Dose-Response Relationship, Drug; Down-Regulation; Drug Therapy, Combination; Etoposide; Male; Rats; Rats, Sprague-Dawley; Selenium; Testosterone; Time Factors; Up-Regulation; Zinc

2014
Glycyrrhetinic acid-modified TPGS polymeric micelles for hepatocellular carcinoma-targeted therapy.
    International journal of pharmaceutics, 2017, Aug-30, Volume: 529, Issue:1-2

    Topics: Carcinoma, Hepatocellular; Drug Carriers; Etoposide; Glycyrrhetinic Acid; Humans; Micelles; Vitamin E

2017
Concomitant solubility-permeability increase: Vitamin E TPGS vs. amorphous solid dispersion as oral delivery systems for etoposide.
    European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft fur Pharmazeutische Verfahrenstechnik e.V, 2017, Volume: 121

    Topics: Administration, Oral; Animals; Antineoplastic Agents; ATP Binding Cassette Transporter, Subfamily B, Member 1; Drug Delivery Systems; Etoposide; Male; Permeability; Rats; Rats, Wistar; Solubility; Surface-Active Agents; Vitamin E

2017
Adequate formulation approach for oral chemotherapy: Etoposide solubility, permeability, and overall bioavailability from cosolvent- vs. vitamin E TPGS-based delivery systems.
    International journal of pharmaceutics, 2021, Mar-15, Volume: 597

    Topics: Administration, Oral; Animals; Biological Availability; Etoposide; Permeability; Polyethylene Glycols; Rats; Solubility; Vitamin E

2021
Gamma-Tocotrienol Synergistically Promotes the Anti-proliferative and Pro-apoptotic Effects of Etoposide on Breast Cancer Cell Lines.
    Current molecular pharmacology, 2022, Volume: 15, Issue:7

    Topics: Breast Neoplasms; Cell Line, Tumor; Cell Proliferation; Chromans; Etoposide; Female; Humans; MCF-7 Cells; Vitamin E

2022