Page last updated: 2024-08-21

d-alpha tocopherol and donepezil

d-alpha tocopherol has been researched along with donepezil in 38 studies

Research

Studies (38)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's7 (18.42)18.2507
2000's22 (57.89)29.6817
2010's8 (21.05)24.3611
2020's1 (2.63)2.80

Authors

AuthorsStudies
Anil, B; Gunesacar, G; Halici, Z; Kasap, Z; Koca, M; Sevindik, H; Turkaydin, K; Yerdelen, KO1
Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K1
He, Y; Liu, W; Mi, J; Sang, Z; Wu, A; Yang, J; Zhou, Y; Zhu, G1
Cummings, JL; Tom, T1
Cummings, JL1
Sunderland, T; Tune, LE1
Karlawish, JH; Whitehouse, PJ1
Pryse-Phillips, W1
Burke, JR; Morgenlander, JC1
Doody, RS1
Cummings, J; Fillit, H1
Allain, H; Belliard, S; Bentue-Ferrer, D; Djemaï, M; Merienne, M; Reymann, JM1
Butler, R; Prabhakaran, P; Warner, J1
Adelman, EE; Karlawish, JH1
Kitamura, S1
Gupta, S1
Foote, RL; Frytak, S; Jatoi, A; Kahanic, SP; Petersen, RC; Schaefer, P; Sloan, J1
Arya, P; Butler, R; Warner, J1
Bennett, D; Doody, R; Ferris, S; Galasko, D; Grundman, M; Jin, S; Kaye, J; Levey, A; Petersen, RC; Pfeiffer, E; Sano, M; Thal, LJ; Thomas, RG; van Dyck, CH1
Blacker, D1
Marder, K1
Barnes, DE; Yaffe, K1
Jelic, V; Kivipelto, M; Winblad, B1
Ownby, RL1
Clark, CM; DeCarli, C; Frisoni, GB; Grundman, M; Harvey, D; Jack, CR; Jin, S; Petersen, RC; Scheltens, P; Thal, LJ1
Fleisher, AS; Gamst, AC; Petersen, RC; Sowell, BB; Taylor, C; Thal, LJ1
Gagnon, E; Robinson, B; Small, BJ1
Doody, RS; Gamst, A; Grundman, M; Jack, CR; Jin, S; Petersen, RC; Sencakova, D; Thal, LJ; Ward, CP1
Feldman, HH; Hsiung, GY1
Barkhof, F; DeCarli, C; Harvey, D; Jack, CR; Petersen, RC; Scheltens, P; Thal, LJ; van Straaten, EC1
Aisen, PS; Ascherio, A; Becerra, LM; Irizarry, MC; Peterson, RC; Raman, R; Schwarzschild, MA; Thomas, RG1
Aisen, PS; Emond, J; Fleisher, AS; Petersen, RC; Raman, R; Sherzai, A; Whitehair, DC1
Aisen, PS; Andrieu, S; Bednar, MM; Carrillo, M; Donohue, M; Doody, RS; Dubois, B; Feldman, HH; Grundman, M; Hendrix, SB; Khachaturian, ZS; Petersen, RC; Potter, WZ; Salmon, D; Salmon, E; Sampaio, C; Schindler, RJ; Schneider, LS; Siemers, E; Thomas, RG; Touchon, J; Vellas, B1
Ahmed, HH1
Au, J; Berry-Kravis, E; Hagerman, R; Lauterborn, J1
Aisen, PS; Cummings, J; Schneider, LS1
Aisen, PS; Donohue, MC; Edland, SD; Galasko, D; Moghadam, SH; Petersen, RC; Rissman, RA; Roe, AD; Sano, M; Sun, CK; Thomas, RG1

Reviews

15 review(s) available for d-alpha tocopherol and donepezil

ArticleYear
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
    Drug discovery today, 2016, Volume: 21, Issue:4

    Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk

2016
New cholinergic therapies: treatment tools for the psychiatrist.
    The Journal of clinical psychiatry, 1998, Volume: 59 Suppl 13

    Topics: Alzheimer Disease; Anti-Inflammatory Agents, Non-Steroidal; Antioxidants; Cholinergic Agents; Cholinesterase Inhibitors; Donepezil; Drug Therapy, Combination; Estrogen Replacement Therapy; Estrogens; Female; Humans; Indans; Male; Piperidines; Selective Serotonin Reuptake Inhibitors; Selegiline; Tacrine; Vitamin E

1998
Is the placebo control obsolete in a world after donepezil and vitamin E?
    Archives of neurology, 1998, Volume: 55, Issue:11

    Topics: Cognition Disorders; Control Groups; Controlled Clinical Trials as Topic; Donepezil; Ethics Committees, Research; Ethics, Medical; Federal Government; Government Regulation; Humans; Indans; Piperidines; Placebos; Research Design; Research Subjects; Risk Assessment; Therapeutic Human Experimentation; Vitamin E

1998
Do we have drugs for dementia? No.
    Archives of neurology, 1999, Volume: 56, Issue:6

    Topics: Alzheimer Disease; Cholinesterase Inhibitors; Dementia; Donepezil; Ginkgo biloba; Humans; Indans; Neuroprotective Agents; Nootropic Agents; Phytotherapy; Piperidines; Plants, Medicinal; Selegiline; Tacrine; Vitamin E

1999
Update on Alzheimer's disease. Promising advances in detection and treatment.
    Postgraduate medicine, 1999, Oct-15, Volume: 106, Issue:5

    Topics: Aged; Alzheimer Disease; Anti-Inflammatory Agents, Non-Steroidal; Cholinesterase Inhibitors; Donepezil; Estrogen Replacement Therapy; Estrogens; Female; Humans; Indans; Piperidines; Vitamin E

1999
Therapeutic standards in Alzheimer disease.
    Alzheimer disease and associated disorders, 1999, Volume: 13 Suppl 2

    Topics: Activities of Daily Living; Alzheimer Disease; Cholinesterase Inhibitors; Cognition; Donepezil; Humans; Indans; Piperidines; Quality of Health Care; Quality of Life; Treatment Outcome; Vitamin E

1999
[Mild Cognitive Impairment: potential therapeutics].
    Revue neurologique, 2002, Volume: 158, Issue:10 Suppl

    Topics: Aged; Alzheimer Disease; Cholinesterase Inhibitors; Cognition Disorders; Donepezil; Dopamine Agonists; Humans; Indans; Neuropsychological Tests; Piperidines; Severity of Illness Index; Vitamin E

2002
Dementia.
    Clinical evidence, 2003, Issue:9

    Topics: Alzheimer Disease; Anticonvulsants; Antipsychotic Agents; Carbamates; Donepezil; Galantamine; Ginkgo biloba; Humans; Indans; Nootropic Agents; Phenylcarbamates; Phosphatidylcholines; Physostigmine; Phytotherapy; Piperidines; Rivastigmine; Tacrine; Vitamin E

2003
[Prognosis in Alzheimer's disease].
    Nihon rinsho. Japanese journal of clinical medicine, 2004, Volume: 62 Suppl

    Topics: Activities of Daily Living; Alzheimer Disease; Cholinesterase Inhibitors; Donepezil; Drug Therapy, Combination; Humans; Indans; Mental Processes; Piperidines; Prognosis; Risk; Selegiline; Survival Rate; Time Factors; Vitamin E

2004
Dementia.
    Clinical evidence, 2004, Issue:11

    Topics: Alzheimer Disease; Antipsychotic Agents; Benzodiazepines; Cognition; Dementia; Donepezil; Galantamine; Ginkgo biloba; Haloperidol; Humans; Indans; Memantine; Olanzapine; Phenylcarbamates; Physostigmine; Phytotherapy; Piperidines; Risperidone; Rivastigmine; Selegiline; Tacrine; Vitamin E

2004
Clinical trials in mild cognitive impairment: lessons for the future.
    Journal of neurology, neurosurgery, and psychiatry, 2006, Volume: 77, Issue:4

    Topics: Aged; Alzheimer Disease; Anti-Inflammatory Agents; Cholinesterase Inhibitors; Clinical Trials as Topic; Cognition Disorders; Donepezil; Galantamine; Humans; Indans; Lactones; Neuropsychological Tests; Phenylcarbamates; Piperidines; Rivastigmine; Severity of Illness Index; Sulfones; Vitamin E

2006
Early identification of cognitive deficits: preclinical Alzheimer's disease and mild cognitive impairment.
    Geriatrics, 2007, Volume: 62, Issue:4

    Topics: Adult; Alzheimer Disease; Cognition Disorders; Disease Progression; Donepezil; Humans; Indans; Neuropsychological Tests; Nootropic Agents; Piperidines; Predictive Value of Tests; Randomized Controlled Trials as Topic; Risk Assessment; Time Factors; Vitamin E

2007
Pharmacological treatment in moderate-to-severe Alzheimer's disease.
    Expert opinion on pharmacotherapy, 2008, Volume: 9, Issue:15

    Topics: Alzheimer Disease; Donepezil; Double-Blind Method; Humans; Indans; Memantine; Phenylcarbamates; Piperidines; Placebos; Randomized Controlled Trials as Topic; Rivastigmine; Selegiline; Severity of Illness Index; Vitamin E

2008
Fragile X syndrome and targeted treatment trials.
    Results and problems in cell differentiation, 2012, Volume: 54

    Topics: Animals; Anti-Bacterial Agents; Antioxidants; Baclofen; Brain-Derived Neurotrophic Factor; Central Nervous System Stimulants; Clinical Trials as Topic; Dendritic Spines; Donepezil; Dopamine; Enzyme Inhibitors; Fragile X Mental Retardation Protein; Fragile X Syndrome; Humans; Indans; Lithium Compounds; Melatonin; Mice; Mice, Knockout; Minocycline; Nootropic Agents; Piperidines; Receptor, Metabotropic Glutamate 5; Receptors, GABA; Receptors, Metabotropic Glutamate; Signal Transduction; Vitamin E

2012
Symptomatic and nonamyloid/tau based pharmacologic treatment for Alzheimer disease.
    Cold Spring Harbor perspectives in medicine, 2012, Volume: 2, Issue:3

    Topics: Alkaloids; Alzheimer Disease; Amino Acids; Animals; Cholinesterase Inhibitors; Dietary Supplements; Disease Progression; Docosahexaenoic Acids; Donepezil; Drug Approval; Galantamine; Ginkgo biloba; Half-Life; History, 20th Century; Humans; Indans; Memantine; Nootropic Agents; Phenylcarbamates; Phytotherapy; Piperidines; Psychotropic Drugs; Receptors, AMPA; Receptors, N-Methyl-D-Aspartate; Rivastigmine; Sesquiterpenes; Vitamin B Complex; Vitamin E

2012

Trials

9 trial(s) available for d-alpha tocopherol and donepezil

ArticleYear
Donepezil and vitamin E for preventing cognitive dysfunction in small cell lung cancer patients: preliminary results and suggestions for future study designs.
    Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer, 2005, Volume: 13, Issue:1

    Topics: Aged; Antioxidants; Carcinoma, Small Cell; Cholinesterase Inhibitors; Cognition Disorders; Donepezil; Double-Blind Method; Female; Humans; Indans; Lung Neoplasms; Male; Piperidines; Vitamin E

2005
Vitamin E and donepezil for the treatment of mild cognitive impairment.
    The New England journal of medicine, 2005, Jun-09, Volume: 352, Issue:23

    Topics: Alzheimer Disease; Apolipoprotein E4; Apolipoproteins E; Cholinesterase Inhibitors; Cognition Disorders; Disease Progression; Donepezil; Double-Blind Method; Humans; Indans; Nootropic Agents; Piperidines; Proportional Hazards Models; Treatment Failure; Vitamin E

2005
Vitamin E and donepezil for the treatment of mild cognitive impairment.
    Current neurology and neuroscience reports, 2005, Volume: 5, Issue:5

    Topics: Aged; Cholinesterase Inhibitors; Cognition Disorders; Confidence Intervals; Donepezil; Double-Blind Method; Female; Humans; Indans; Male; Neuropsychological Tests; Piperidines; Retrospective Studies; Treatment Outcome; Vitamin E

2005
Donepezil and vitamin E for mild cognitive impairment.
    Current psychiatry reports, 2006, Volume: 8, Issue:1

    Topics: Alzheimer Disease; Cognition Disorders; Donepezil; Humans; Indans; Long-Term Care; Piperidines; Treatment Outcome; Vitamin E

2006
Qualitative estimates of medial temporal atrophy as a predictor of progression from mild cognitive impairment to dementia.
    Archives of neurology, 2007, Volume: 64, Issue:1

    Topics: Aged; Aged, 80 and over; Atrophy; Cognition Disorders; Dementia; Disease Progression; Donepezil; Double-Blind Method; Female; Humans; Indans; Kaplan-Meier Estimate; Magnetic Resonance Imaging; Male; Neuropsychological Tests; Nootropic Agents; Piperidines; Predictive Value of Tests; Reproducibility of Results; Temporal Lobe; Vitamin E

2007
Clinical predictors of progression to Alzheimer disease in amnestic mild cognitive impairment.
    Neurology, 2007, May-08, Volume: 68, Issue:19

    Topics: Age Distribution; Aged; Aged, 80 and over; Alzheimer Disease; Amnesia; Antioxidants; Apolipoprotein E4; Cholinesterase Inhibitors; Cognition Disorders; Cohort Studies; Disease Progression; Donepezil; Female; Genotype; Humans; Indans; Linear Models; Male; Neuropsychological Tests; Piperidines; Placebo Effect; Predictive Value of Tests; Prognosis; Sex Distribution; Vitamin E

2007
Longitudinal MRI findings from the vitamin E and donepezil treatment study for MCI.
    Neurobiology of aging, 2008, Volume: 29, Issue:9

    Topics: Aged; Aged, 80 and over; Antioxidants; Atrophy; Cholinesterase Inhibitors; Cognition Disorders; Donepezil; Female; Hippocampus; Humans; Incidence; Indans; Longitudinal Studies; Male; Middle Aged; Piperidines; Treatment Outcome; United States; Vitamin E

2008
Periventricular white matter hyperintensities increase the likelihood of progression from amnestic mild cognitive impairment to dementia.
    Journal of neurology, 2008, Volume: 255, Issue:9

    Topics: Aged; Aged, 80 and over; Alzheimer Disease; Amnesia; Antioxidants; Atrophy; Brain; Cerebral Ventricles; Cholinesterase Inhibitors; Cognition Disorders; Dementia; Disease Progression; Donepezil; Double-Blind Method; Female; Humans; Image Processing, Computer-Assisted; Indans; Magnetic Resonance Imaging; Male; Piperidines; Prospective Studies; Temporal Lobe; Time Factors; Treatment Outcome; Vitamin E

2008
Longitudinal plasma amyloid beta in Alzheimer's disease clinical trials.
    Alzheimer's & dementia : the journal of the Alzheimer's Association, 2015, Volume: 11, Issue:9

    Topics: Aged; Alzheimer Disease; Amyloid beta-Peptides; Apolipoprotein E4; Biomarkers; Blood Chemical Analysis; Cognitive Dysfunction; Disease Progression; Donepezil; Female; Heterozygote; Humans; Indans; Longitudinal Studies; Male; Nootropic Agents; Peptide Fragments; Piperidines; Severity of Illness Index; Simvastatin; Vitamin E

2015

Other Studies

14 other study(ies) available for d-alpha tocopherol and donepezil

ArticleYear
Synthesis of donepezil-based multifunctional agents for the treatment of Alzheimer's disease.
    Bioorganic & medicinal chemistry letters, 2015, Dec-01, Volume: 25, Issue:23

    Topics: Alzheimer Disease; Amides; Amyloid beta-Peptides; Catalytic Domain; Cholinesterase Inhibitors; Donepezil; Drug Design; Indans; Inhibitory Concentration 50; Models, Molecular; Piperidines; Structure-Activity Relationship

2015
Development of naringenin-O-carbamate derivatives as multi-target-directed liagnds for the treatment of Alzheimer's disease.
    Bioorganic & medicinal chemistry letters, 2022, 03-15, Volume: 60

    Topics: Acetylcholinesterase; Alzheimer Disease; Amyloid beta-Peptides; Animals; Antioxidants; Butyrylcholinesterase; Carbamates; Cell Line; Cell Survival; Cholinesterase Inhibitors; Copper; Dose-Response Relationship, Drug; Drug Development; Flavanones; Humans; Molecular Structure; Neuroprotective Agents; Peptide Fragments; Protein Aggregates; Rats; Structure-Activity Relationship

2022
Drug treatment for Alzheimer's disease.
    The Western journal of medicine, 1998, Volume: 168, Issue:4

    Topics: Alzheimer Disease; Cholinesterase Inhibitors; Donepezil; Drug Therapy, Combination; Estrogen Replacement Therapy; Female; Humans; Indans; Male; Neuroprotective Agents; Piperidines; Selegiline; Vitamin E

1998
Alzheimer's disease management.
    The Journal of clinical psychiatry, 1998, Volume: 59 Suppl 13

    Topics: Aged; Aged, 80 and over; Alzheimer Disease; Cholinesterase Inhibitors; Donepezil; Humans; Indans; Middle Aged; Piperidines; Selegiline; Tacrine; Vitamin E

1998
Practice guidelines for the diagnosis and treatment of Alzheimer's disease in a managed care setting: Part II--Pharmacologic therapy. Alzheimer's Disease (AD) Managed Care Advisory Council.
    Managed care interface, 2000, Volume: 13, Issue:1

    Topics: Algorithms; Alzheimer Disease; Anti-Inflammatory Agents, Non-Steroidal; Antioxidants; Caregivers; Cholinesterase Inhibitors; Clinical Trials as Topic; Cost-Benefit Analysis; Donepezil; Drug Interactions; Estrogens; Female; Ginkgo biloba; Humans; Indans; Male; Managed Care Programs; Nootropic Agents; Patient Selection; Phytotherapy; Piperidines; Plants, Medicinal; Psychotropic Drugs; Quality of Health Care; Selegiline; Tacrine; Time Factors; Vitamin E

2000
Ignoring the controversies: newspaper reports on Alzheimer's disease treatments.
    Journal of the American Geriatrics Society, 2003, Volume: 51, Issue:12

    Topics: Alzheimer Disease; Canada; Donepezil; Humans; Indans; Newspapers as Topic; Nootropic Agents; Piperidines; United Kingdom; United States; Vitamin E

2003
Delaying Alzheimer's. In a new study, Aricept held it off for 18 months. Is this drug right for you?
    Time, 2004, Aug-02, Volume: 164, Issue:5

    Topics: Alzheimer Disease; Donepezil; Humans; Indans; Nootropic Agents; Piperidines; Placebos; Randomized Controlled Trials as Topic; Treatment Outcome; United States; Vitamin E

2004
Mild cognitive impairment--no benefit from vitamin E, little from donepezil.
    The New England journal of medicine, 2005, Jun-09, Volume: 352, Issue:23

    Topics: Alzheimer Disease; Apolipoprotein E4; Apolipoproteins E; Cholinesterase Inhibitors; Cognition Disorders; Disease Progression; Donepezil; Humans; Indans; Nootropic Agents; Piperidines; Treatment Failure; Vitamin E

2005
Drug may temporarily slow progression of mild cognitive impairment.
    Mayo Clinic women's healthsource, 2005, Volume: 9, Issue:8

    Topics: Alzheimer Disease; Cognition Disorders; Donepezil; Female; Humans; Indans; Nootropic Agents; Piperidines; Vitamin E

2005
Vitamin E and donepezil for the treatment of mild cognitive impairment.
    The New England journal of medicine, 2005, Sep-01, Volume: 353, Issue:9

    Topics: Alzheimer Disease; Apolipoprotein E4; Apolipoproteins E; Cholinesterase Inhibitors; Data Interpretation, Statistical; Disease Progression; Donepezil; Heterozygote; Humans; Indans; Piperidines; Vitamin E

2005
Plasma urate and progression of mild cognitive impairment.
    Neuro-degenerative diseases, 2009, Volume: 6, Issue:1-2

    Topics: Aged; Aged, 80 and over; Alzheimer Disease; Boston; Cognition Disorders; Confounding Factors, Epidemiologic; Dementia; Disease Progression; Donepezil; Female; Humans; Incidence; Indans; Male; Middle Aged; Nootropic Agents; Piperidines; Prevalence; Survival Analysis; Uric Acid; Vitamin E

2009
Influence of apolipoprotein E varepsilon4 on rates of cognitive and functional decline in mild cognitive impairment.
    Alzheimer's & dementia : the journal of the Alzheimer's Association, 2010, Volume: 6, Issue:5

    Topics: Aged; Aged, 80 and over; Apolipoprotein E4; Cholinesterase Inhibitors; Cognition Disorders; Disease Progression; Donepezil; Female; Follow-Up Studies; Genotype; Humans; Indans; Male; Middle Aged; Neuropsychological Tests; Piperidines; Psychiatric Status Rating Scales; Randomized Controlled Trials as Topic; Retrospective Studies; Vitamin E

2010
Report of the task force on designing clinical trials in early (predementia) AD.
    Neurology, 2011, Jan-18, Volume: 76, Issue:3

    Topics: Advisory Committees; Alzheimer Disease; Amyloidogenic Proteins; Biomarkers; Clinical Trials as Topic; Cognition; Consensus; Disease Progression; Donepezil; Drug Industry; Early Diagnosis; Europe; Humans; Indans; International Cooperation; Nootropic Agents; Outcome Assessment, Health Care; Patient Selection; Piperidines; Positron-Emission Tomography; Research Design; Treatment Outcome; United States; United States Food and Drug Administration; Vitamin E

2011
Modulatory effects of vitamin E, acetyl-L-carnitine and α-lipoic acid on new potential biomarkers for Alzheimer's disease in rat model.
    Experimental and toxicologic pathology : official journal of the Gesellschaft fur Toxikologische Pathologie, 2012, Volume: 64, Issue:6

    Topics: Alzheimer Disease; Animals; Antioxidants; Biomarkers; Brain; Carnitine; Cholinesterase Inhibitors; Dietary Supplements; Disease Models, Animal; Donepezil; Enzyme-Linked Immunosorbent Assay; Homocysteine; Indans; Insulin-Like Growth Factor I; Interleukin-1beta; Male; Piperidines; Rats; Rats, Sprague-Dawley; Thioctic Acid; Tumor Necrosis Factor-alpha; Vitamin E

2012