Page last updated: 2024-08-21

d-alpha tocopherol and cyclic gmp

d-alpha tocopherol has been researched along with cyclic gmp in 22 studies

Research

Studies (22)

TimeframeStudies, this research(%)All Research%
pre-19902 (9.09)18.7374
1990's7 (31.82)18.2507
2000's11 (50.00)29.6817
2010's2 (9.09)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Kasai, H; Makino, H; Sakai, T; Tanaka, R; Yamanaka, H1
Munkres, KD1
Schroeder, J1
Alanko, J; Mucha, I; Riutta, A; Vapaatalo, H1
Dittrich, P; Graier, WF; Hoebel, BG; Kostner, GM; Simecek, S; Wascher, TC1
Kakihana, M; Ohtsuka, S; Sugishita, Y; Watanabe, H2
Giugliano, D; Marfella, R1
Knox, FG; Liang, M1
Berggren, PO; Cooney, RV; Sjöholm, A1
Caccitolo, JA; Lerman, A; Lerman, LO; Napoli, C; Porcel, MR; Romero, JC; Schaff, HV; Stulak, JM1
Holmes, DR; Lerman, A; Lerman, LO; Napoli, C; Richardson, D; Rodriguez-Porcel, M1
d'Uscio, LV; Katusic, ZS; Milstien, S; Richardson, D; Smith, L1
Herrmann, J; Lerman, A; Lerman, LO; Napoli, C; Rodriguez-Porcel, M; Sawamura, T1
Arockia Rani P, J; Fukatsu, A; Hayashi, T; Iguchi, A; Kano, H; Matsui-Hirai, H; Sumi, D; Tsunekawa, T1
Heller, R; Werner, ER; Werner-Felmayer, G1
Fukatsu, A; Funami, J; Hayashi, T; Ignarro, LJ; Iguchi, A; Juliet, PA; Matsui-Hirai, H; Miyazaki, A1
Hai, S; Minamiyama, Y; Okada, S; Suehiro, S; Takemura, S1
Aggeli, IK; Andreadou, I; Beis, I; Gaitanaki, C; Iliodromitis, EK; Kremastinos, DT; Markantonis, SL; Paraskevaidis, IA; Tsovolas, K; Zoga, A1
Katayama, S; Kuramochi, T; Ushiyama, M; Yagi, S1
Beyer, AJ; Chen, J; Chen, Q; Gerdes, AM; Harris, WS; Healy, CL; Nareddy, VB; O'Connell, TD; Shearer, GC; Wang, D1
Chernichovski, T; Chernin, G; Grupper, A; Hershkoviz, R; Hillel, O; Ingbir, M; Laron, I; Schwartz, D; Schwartz, IF; Shashar, M; Shtabski, A; Soetendorp, H; Weinstein, T1

Trials

2 trial(s) available for d-alpha tocopherol and cyclic gmp

ArticleYear
Randomized, double-blind, placebo-controlled study of supplemental vitamin E on attenuation of the development of nitrate tolerance.
    Circulation, 1997, Oct-21, Volume: 96, Issue:8

    Topics: Administration, Oral; Adult; Aged; Antioxidants; Blood Platelets; Cyclic GMP; Double-Blind Method; Drug Interactions; Drug Tolerance; Female; Forearm; Humans; Male; Middle Aged; Myocardial Ischemia; Nitroglycerin; Plethysmography; Regional Blood Flow; Vasodilator Agents; Vitamin E

1997
Randomized, double-blind, placebo-controlled study of ascorbate on the preventive effect of nitrate tolerance in patients with congestive heart failure.
    Circulation, 1998, Mar-10, Volume: 97, Issue:9

    Topics: Aged; Ascorbic Acid; Blood Platelets; Blood Pressure; Cyclic GMP; Double-Blind Method; Drug Tolerance; Female; Heart Failure; Humans; Infusions, Intravenous; Male; Nitroglycerin; Vitamin E

1998

Other Studies

20 other study(ies) available for d-alpha tocopherol and cyclic gmp

ArticleYear
Stimulation of cyclic nucleotide phosphodiesterases from rat brain by activator protein, proteolytic enzymes and a vitamin E derivative.
    Biochimica et biophysica acta, 1977, Jul-08, Volume: 483, Issue:1

    Topics: 3',5'-Cyclic-AMP Phosphodiesterases; Animals; Brain; Calcium; Carrier Proteins; Chromatography, Affinity; Chromatography, DEAE-Cellulose; Cyclic GMP; Enzyme Activation; Kinetics; Male; Molecular Weight; Nerve Tissue Proteins; Peptide Hydrolases; Phosphoric Diester Hydrolases; Rats; Trypsin; Vitamin E

1977
Pharmacogenetics of cyclic guanylate, antioxidants, and antioxidant enzymes in Saccharomyces.
    Free radical biology & medicine, 1990, Volume: 9, Issue:1

    Topics: Antioxidants; Catalase; Cell Differentiation; Copper; Cyclic GMP; Drug Resistance, Microbial; Free Radicals; Iron; Lighting; Mutation; Oxygen; Paraquat; Saccharomyces; Superoxide Dismutase; Theophylline; Vitamin E

1990
Analogs of alpha-tocopherol as inhibitors of cyclic-AMP and cyclic-GMP phosphodiesterases and effects of alpha-tocopherol deficiency on cyclic AMP-controlled metabolism.
    Biochimica et biophysica acta, 1974, Mar-20, Volume: 343, Issue:1

    Topics: Animals; Body Weight; Cattle; Cyclic AMP; Cyclic GMP; Glycogen; Kinetics; L-Serine Dehydratase; Liver; Male; Organ Size; Phosphodiesterase Inhibitors; Rats; Structure-Activity Relationship; Theophylline; Vitamin E; Vitamin E Deficiency

1974
Effects of Trolox C and SIN-1 on arachidonic acid metabolism and on cyclic GMP formation in leukocytes.
    European journal of pharmacology, 1994, Sep-12, Volume: 262, Issue:3

    Topics: Antioxidants; Arachidonic Acid; Calcimycin; Centrifugation, Density Gradient; Chromans; Cyclic GMP; Dibutyryl Cyclic GMP; Dinoprostone; Dose-Response Relationship, Drug; Guanylate Cyclase; Humans; Leukotriene B4; Molsidomine; Neutrophils; Radioimmunoassay; Vasodilator Agents; Vitamin E

1994
Antioxidants prevent high-D-glucose-enhanced endothelial Ca2+/cGMP response by scavenging superoxide anions.
    European journal of pharmacology, 1997, Mar-12, Volume: 322, Issue:1

    Topics: Animals; Antioxidants; Ascorbic Acid; Calcium; Cells, Cultured; Cyclic GMP; Cytosol; Endothelium, Vascular; Free Radical Scavengers; Glucose; Glutathione; Hypolipidemic Agents; Nitric Oxide; Probucol; Superoxides; Swine; Vitamin E

1997
Antioxidants and nitrate tolerance.
    Circulation, 1998, Sep-29, Volume: 98, Issue:13

    Topics: Antioxidants; Cyclic GMP; Drug Tolerance; Humans; Nitroglycerin; Vitamin E

1998
Nitric oxide reduces the molecular activity of Na+,K+-ATPase in opossum kidney cells.
    Kidney international, 1999, Volume: 56, Issue:2

    Topics: Animals; Anticholesteremic Agents; Antihypertensive Agents; Cells, Cultured; Cyclic GMP; Enzyme Inhibitors; Kidney Tubules, Proximal; Lipid Peroxidation; Nitric Oxide; Nitroprusside; Opossums; Ouabain; Probucol; Protein Binding; Signal Transduction; Sodium-Potassium-Exchanging ATPase; Vitamin E

1999
gamma-tocopherol partially protects insulin-secreting cells against functional inhibition by nitric oxide.
    Biochemical and biophysical research communications, 2000, Oct-22, Volume: 277, Issue:2

    Topics: Adenylyl Cyclases; Animals; Calcium; Calcium Channels; Carbachol; Cell Division; Cell Line; Cell Survival; Cholinergic Agonists; Colforsin; Cyclic GMP; Enzyme Inhibitors; Insulin; Insulin Secretion; Insulinoma; Interleukin-1; Islets of Langerhans; Models, Chemical; Nitric Oxide; Nitrogen Oxides; Oxadiazoles; Phorbol Esters; Protein Kinase C; Quinoxalines; Rats; Spermine; Type C Phospholipases; Vitamin E

2000
Renal vascular function in hypercholesterolemia is preserved by chronic antioxidant supplementation.
    Journal of the American Society of Nephrology : JASN, 2001, Volume: 12, Issue:9

    Topics: Animals; Antioxidants; Ascorbic Acid; Cholesterol; Cholesterol, Dietary; Cyclic GMP; Endothelium, Vascular; Hemodynamics; Hypercholesterolemia; Immunohistochemistry; In Vitro Techniques; Lipoproteins, LDL; Muscle, Smooth, Vascular; Reference Values; Renal Circulation; Swine; Time Factors; Tomography, X-Ray Computed; Vitamin E

2001
Chronic antioxidant supplementation attenuates nuclear factor-kappa B activation and preserves endothelial function in hypercholesterolemic pigs.
    Cardiovascular research, 2002, Volume: 53, Issue:4

    Topics: Animals; Antioxidants; Ascorbic Acid; Cholesterol; Cyclic GMP; Dietary Supplements; Endothelium, Vascular; Female; Hypercholesterolemia; Muscle, Smooth, Vascular; NF-kappa B; Nitric Oxide Synthase; Oxidative Stress; Swine; Vitamin E

2002
Long-term vitamin C treatment increases vascular tetrahydrobiopterin levels and nitric oxide synthase activity.
    Circulation research, 2003, Jan-10, Volume: 92, Issue:1

    Topics: Animals; Aorta; Apolipoproteins E; Arteriosclerosis; Ascorbic Acid; Biopterins; Cyclic AMP; Cyclic GMP; Dietary Supplements; Disease Models, Animal; Endothelium, Vascular; Enzyme Activation; In Vitro Techniques; Lipids; Male; Mice; Mice, Inbred C57BL; Mice, Mutant Strains; Nitric Oxide Synthase; Nitric Oxide Synthase Type II; Nitric Oxide Synthase Type III; Superoxides; Time; Tyrosine; Vasomotor System; Vitamin E

2003
Hypercholesterolemia and hypertension have synergistic deleterious effects on coronary endothelial function.
    Arteriosclerosis, thrombosis, and vascular biology, 2003, May-01, Volume: 23, Issue:5

    Topics: Animals; Antioxidants; Ascorbic Acid; Bradykinin; Calcimycin; Coronary Artery Disease; Coronary Vessels; Cyclic GMP; Diet, Atherogenic; Endothelin-1; Endothelium, Vascular; Female; Hemodynamics; Hypercholesterolemia; Hypertension, Renovascular; Lipids; Nitric Oxide; Nitroprusside; Oxidative Stress; Renal Artery Obstruction; Renin; Substance P; Swine; Vasodilator Agents; Vitamin E

2003
Sarpogrelate HCl, a selective 5-HT2A antagonist, retards the progression of atherosclerosis through a novel mechanism.
    Atherosclerosis, 2003, Volume: 168, Issue:1

    Topics: Acetylcholine; Animals; Antioxidants; Aorta, Thoracic; Biomarkers; Blood Proteins; Cholesterol, HDL; Coronary Artery Disease; Cyclic GMP; Disease Models, Animal; Disease Progression; Dose-Response Relationship, Drug; Endothelium, Vascular; Hypercholesterolemia; Male; Matrix Metalloproteinase 1; Matrix Metalloproteinase 2; Models, Cardiovascular; Myocardial Contraction; Myocytes, Smooth Muscle; Nitric Oxide Synthase; Nitric Oxide Synthase Type II; Nitric Oxide Synthase Type III; Rabbits; RNA, Messenger; Serotonin Antagonists; Succinates; Treatment Outcome; Vasodilator Agents; Vitamin E

2003
Alpha-Tocopherol and endothelial nitric oxide synthesis.
    Annals of the New York Academy of Sciences, 2004, Volume: 1031

    Topics: alpha-Tocopherol; Biopterins; Cells, Cultured; Citrulline; Cyclic GMP; Endothelium, Vascular; Humans; Nitric Oxide; Nitric Oxide Synthase; Nitric Oxide Synthase Type III; Phosphorylation; Serine; Umbilical Veins

2004
l-Citrulline and l-arginine supplementation retards the progression of high-cholesterol-diet-induced atherosclerosis in rabbits.
    Proceedings of the National Academy of Sciences of the United States of America, 2005, Sep-20, Volume: 102, Issue:38

    Topics: Animals; Antioxidants; Aorta, Thoracic; Arginine; Arteriosclerosis; Ascorbic Acid; Citrulline; Cyclic AMP Response Element-Binding Protein; Cyclic GMP; Diet, Atherogenic; DNA-Binding Proteins; Endothelium, Vascular; ets-Domain Protein Elk-1; Humans; Male; Nitrates; Nitric Oxide Synthase; Nitric Oxide Synthase Type III; Nitrites; Oxidation-Reduction; Proto-Oncogene Proteins; Rabbits; Superoxides; Transcription Factors; Vasodilation; Vitamin E

2005
Vitamin E deficiency accelerates nitrate tolerance via a decrease in cardiac P450 expression and increased oxidative stress.
    Free radical biology & medicine, 2006, Mar-01, Volume: 40, Issue:5

    Topics: alpha-Tocopherol; Animals; Aorta; Cell Adhesion Molecules; Cyclic GMP; Cytochrome P-450 CYP1A2; Down-Regulation; Drug Tolerance; Lipid Peroxidation; Male; Microfilament Proteins; Myocardium; Nitrates; Nitric Oxide; Nitroglycerin; Oxidative Stress; Phosphoproteins; Phosphorylation; Rats; Reactive Oxygen Species; Serine; Vasodilator Agents; Vitamin E; Vitamin E Deficiency

2006
Acute administration of vitamin E triggers preconditioning via K(ATP) channels and cyclic-GMP without inhibiting lipid peroxidation.
    Free radical biology & medicine, 2006, Oct-01, Volume: 41, Issue:7

    Topics: Animals; Blood Pressure; Cyclic GMP; Dose-Response Relationship, Drug; Heart Rate; Ischemic Preconditioning, Myocardial; Lipid Peroxidation; Male; Malondialdehyde; Models, Animal; Myocardium; Potassium Channels; Rabbits; Vitamin E

2006
Antioxidant treatment with alpha-tocopherol improves erectile function in hypertensive rats.
    Hypertension research : official journal of the Japanese Society of Hypertension, 2008, Volume: 31, Issue:5

    Topics: alpha-Tocopherol; Animals; Antioxidants; Blood Pressure; Carbon Monoxide; Cyclic GMP; Disease Models, Animal; Dose-Response Relationship, Drug; Electric Stimulation; Heme Oxygenase (Decyclizing); Hypertension; Male; Nitric Oxide; Nitric Oxide Synthase Type I; Nitric Oxide Synthase Type III; Penile Erection; Rats; Rats, Inbred SHR; Superoxide Dismutase; Thiobarbituric Acid Reactive Substances

2008
Omega-3 fatty acids prevent pressure overload-induced cardiac fibrosis through activation of cyclic GMP/protein kinase G signaling in cardiac fibroblasts.
    Circulation, 2011, Feb-15, Volume: 123, Issue:6

    Topics: Animals; Cyclic GMP; Cyclic GMP-Dependent Protein Kinases; Dietary Supplements; Fatty Acids, Omega-3; Fibroblasts; Fibrosis; Heart Ventricles; Male; Mice; Mice, Inbred C57BL; Nitric Oxide; Nitric Oxide Synthase Type III; Signal Transduction; Smad2 Protein; Smad3 Protein; Transforming Growth Factor beta1; Up-Regulation; Ventricular Dysfunction, Left; Ventricular Remodeling; Vitamin E

2011
Attenuated glomerular arginine transport prevents hyperfiltration and induces HIF-1α in the pregnant uremic rat.
    American journal of physiology. Renal physiology, 2012, Aug-01, Volume: 303, Issue:3

    Topics: Animals; Arginine; Biological Transport, Active; Blotting, Western; Cationic Amino Acid Transporter 1; Chromatography, High Pressure Liquid; Cyclic GMP; Female; Glomerular Filtration Rate; Hypoxia-Inducible Factor 1, alpha Subunit; Immunoprecipitation; Inulin; Kidney Glomerulus; Nitric Oxide Synthase Type III; p-Aminohippuric Acid; Phosphorylation; Pregnancy; Pregnancy Complications; Protein Kinase C-alpha; Rats; Rats, Wistar; Renal Circulation; Uremia; Vitamin E

2012