Page last updated: 2024-08-21

d-alpha tocopherol and 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine

d-alpha tocopherol has been researched along with 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine in 17 studies

Research

Studies (17)

TimeframeStudies, this research(%)All Research%
pre-19909 (52.94)18.7374
1990's4 (23.53)18.2507
2000's2 (11.76)29.6817
2010's1 (5.88)24.3611
2020's1 (5.88)2.80

Authors

AuthorsStudies
Heikkila, RE; Sieber, BA; Terleckyj, I1
Cadet, JL1
Bergeron, C; Foulks, JG; Hansen, S; Jones, K; Perry, TL; Wright, JM; Yong, VW1
Di Monte, D; Sandy, MS; Smith, MT1
Hirai, S1
Cohen, P; Di Monte, D; Sandy, MS; Smith, MT1
Krisman, AA; Perry, TL; Yong, VW1
Cohen, O; Martinovits, G; Melamed, E; Rosenthal, J; Uzzan, A1
Angelucci, L; Fariello, RG; Ghirardi, O; Peschechera, A; Ramacci, MT1
Clavier, RM; Foulks, JG; Jones, K; Perry, TL; Wall, RA; Wright, JM; Yong, VW1
Andersen, JK; Jurma, OP; Wei, Q; Yeung, M1
Jiang, DH; Lan, J1
Selley, ML1
Cynshi, O; Itoh, N; Jishage, K; Masuo, Y; Niki, E; Yoshida, Y1
Jishage, K; Mizuno, Y; Mochizuki, H; Nishida, Y; Ren, YR; Uchihara, T; Yasuda, T; Yokota, T; Yoshimi, K1
Gómez-Rodríguez, VM; González-Renovato, ED; Ortiz, GG; Pacheco-Moisés, FP; Ramírez-Anguiano, AC; Torres-Sánchez, ED1
Ahmad, R; Ali, J; Atiq, A; Choe, K; Kang, MH; Khan, A; Kim, MO; Lee, HJ; Park, JS; Rehman, IU; Tahir, M1

Reviews

1 review(s) available for d-alpha tocopherol and 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine

ArticleYear
Desferrioxamine and vitamin E protect against iron and MPTP-induced neurodegeneration in mice.
    Journal of neural transmission (Vienna, Austria : 1996), 1997, Volume: 104, Issue:4-5

    Topics: 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine; 3,4-Dihydroxyphenylacetic Acid; Animals; Brain Diseases; Corpus Striatum; Deferoxamine; Dopamine; Female; Glutathione; Glutathione Disulfide; Hydroxyl Radical; Iron; Lipid Peroxides; Male; Mice; Nerve Degeneration; Osmolar Concentration; Vitamin E

1997

Other Studies

16 other study(ies) available for d-alpha tocopherol and 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine

ArticleYear
Monoamine oxidase and the bioactivation of MPTP and related neurotoxins: relevance to DATATOP.
    Journal of neural transmission. Supplementum, 1990, Volume: 32

    Topics: 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine; Animals; Biotransformation; Brain; Humans; In Vitro Techniques; Male; Mice; Monoamine Oxidase; Nervous System; Neurotoxins; Oxidation-Reduction; Parkinson Disease; Rats; Rats, Inbred Strains; Selegiline; Vitamin E

1990
The potential use of vitamin E and selenium in parkinsonism.
    Medical hypotheses, 1986, Volume: 20, Issue:1

    Topics: 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine; Animals; Disease Models, Animal; Humans; Hydroxydopamines; Neurons; Oxidopamine; Parkinson Disease; Pyridines; Rats; Selenium; Vitamin E

1986
Alpha-tocopherol and beta-carotene do not protect marmosets against the dopaminergic neurotoxicity of N-methyl-4-phenyl-1,2,3,6-tetrahydropyridine.
    Journal of the neurological sciences, 1987, Volume: 81, Issue:2-3

    Topics: 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine; Animals; beta Carotene; Brain; Callitrichinae; Carotenoids; Corpus Striatum; Dopamine; Drug Interactions; Male; Pyridines; Substantia Nigra; Vitamin E

1987
Relationships between intracellular vitamin E, lipid peroxidation, and chemical toxicity in hepatocytes.
    Toxicology and applied pharmacology, 1988, Volume: 93, Issue:2

    Topics: 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine; 1-Methyl-4-phenylpyridinium; Adenosine Diphosphate; Animals; Carmustine; Diquat; Dithiothreitol; Dose-Response Relationship, Drug; Glutathione; In Vitro Techniques; Lipid Peroxides; Liver; Male; Phenylenediamines; Pyridines; Pyridinium Compounds; Rats; Rats, Inbred Strains; Vitamin E

1988
[Biochemistry of the physiopathologic and clinical aspects of free radicals in cerebral degenerative diseases such as Alzheimer's and Parkinson diseases].
    Nihon rinsho. Japanese journal of clinical medicine, 1988, Volume: 46, Issue:10

    Topics: 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine; Alzheimer Disease; Animals; Catecholamines; Free Radicals; Humans; Lipid Peroxides; Monoamine Oxidase; Parkinson Disease; Pyridines; Superoxide Dismutase; Vitamin E

1988
Role of active oxygen in paraquat and 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP) cytotoxicity.
    Basic life sciences, 1988, Volume: 49

    Topics: 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine; Animals; Antioxidants; Carmustine; Cell Survival; Cells, Cultured; Deferoxamine; Free Radicals; Lipid Peroxidation; Liver; Paraquat; Phenylenediamines; Pyridines; Rats; Reference Values; Vitamin E

1988
Depletion of glutathione in brainstem of mice caused by N-methyl-4-phenyl-1,2,3,6-tetrahydropyridine is prevented by antioxidant pretreatment.
    Neuroscience letters, 1986, Jan-02, Volume: 63, Issue:1

    Topics: 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine; Animals; Antioxidants; beta Carotene; Brain Stem; Carotenoids; Corpus Striatum; Dopamine; Glutathione; Male; Mice; Mice, Inbred C57BL; Premedication; Pyridines; Substantia Nigra; Vitamin E

1986
Systemic administration of antioxidants does not protect mice against the dopaminergic neurotoxicity of 1-methyl-4-phenyl-1,2,5,6-tetrahydropyridine (MPTP).
    Neuroscience letters, 1986, Aug-29, Volume: 69, Issue:2

    Topics: 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine; Animals; Antioxidants; Ascorbic Acid; Brain Chemistry; Corpus Striatum; Dimethyl Sulfoxide; Dopamine; Drug Administration Schedule; Drug Combinations; Injections, Subcutaneous; Male; Mice; Mice, Inbred C57BL; Neurotoxins; Pyridines; Substantia Nigra; Vitamin E

1986
Transient nigral ubiquinone depletion after single MPTP administration in mice.
    Neuropharmacology, 1987, Volume: 26, Issue:12

    Topics: 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine; Animals; Dopamine; Female; Mice; Pyridines; Substantia Nigra; Ubiquinone; Vitamin E

1987
Partial protection from the dopaminergic neurotoxin N-methyl-4-phenyl-1,2,3,6-tetrahydropyridine by four different antioxidants in the mouse.
    Neuroscience letters, 1985, Sep-30, Volume: 60, Issue:2

    Topics: 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine; Acetylcysteine; Animals; Antioxidants; Ascorbic Acid; Carotenoids; Corpus Striatum; Male; Mice; Mice, Inbred C57BL; Neural Pathways; Pyridines; Substantia Nigra; Vitamin E

1985
Genetic elevation of monoamine oxidase levels in dopaminergic PC12 cells results in increased free radical damage and sensitivity to MPTP.
    Journal of neuroscience research, 1996, Dec-15, Volume: 46, Issue:6

    Topics: 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine; Animals; Cell Survival; Dopamine; Dopamine Agents; Free Radicals; Gene Expression Regulation, Enzymologic; Humans; Monoamine Oxidase; Monoamine Oxidase Inhibitors; Neurotoxins; PC12 Cells; Plasmids; Rats; Selegiline; Sensitivity and Specificity; Vitamin E

1996
(E)-4-hydroxy-2-nonenal may be involved in the pathogenesis of Parkinson's disease.
    Free radical biology & medicine, 1998, Jul-15, Volume: 25, Issue:2

    Topics: 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine; Adult; Aged; Aldehydes; Animals; Brain Stem; Cross-Linking Reagents; Drug Administration Routes; Glutathione; Humans; Injections, Subcutaneous; Male; Mice; Middle Aged; Parkinson Disease; Substantia Nigra; Time Factors; Vitamin E

1998
gamma-Tocopherol attenuates MPTP-induced dopamine loss more efficiently than alpha-tocopherol in mouse brain.
    Neuroscience letters, 2006, Jul-31, Volume: 403, Issue:1-2

    Topics: 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine; alpha-Tocopherol; Animals; Antioxidants; Brain; Dopamine; gamma-Tocopherol; Immunohistochemistry; Mice; Mice, Inbred C57BL; Mice, Knockout; Neurons; Vitamins

2006
Genetic vitamin E deficiency does not affect MPTP susceptibility in the mouse brain.
    Journal of neurochemistry, 2006, Volume: 98, Issue:6

    Topics: 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine; Administration, Oral; Animals; Brain; Corpus Striatum; Disease Susceptibility; Dopamine Antagonists; Genotype; Glutathione; Mice; Mice, Inbred C57BL; Mice, Knockout; Neurotoxins; Parkinsonian Disorders; Substantia Nigra; Superoxide Dismutase; Superoxide Dismutase-1; Vitamin E; Vitamin E Deficiency

2006
Fish oil, melatonin and vitamin E attenuates midbrain cyclooxygenase-2 activity and oxidative stress after the administration of 1-methyl-4-phenyl-1,2,3,6- tetrahydropyridine.
    Metabolic brain disease, 2013, Volume: 28, Issue:4

    Topics: 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine; Animals; Cyclooxygenase 2; Fish Oils; Lipid Peroxidation; Melatonin; Mesencephalon; Mice; Mice, Inbred C57BL; Oxidative Stress; Vitamin E

2013
Vitamin E Analog Trolox Attenuates MPTP-Induced Parkinson's Disease in Mice, Mitigating Oxidative Stress, Neuroinflammation, and Motor Impairment.
    International journal of molecular sciences, 2023, Jun-09, Volume: 24, Issue:12

    Topics: 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine; Animals; Disease Models, Animal; Dopaminergic Neurons; Mice; Mice, Inbred C57BL; Motor Disorders; Neuroinflammatory Diseases; Neuroprotective Agents; Oxidative Stress; Parkinson Disease; Substantia Nigra; Tyrosine 3-Monooxygenase; Vitamin E

2023