cytosine has been researched along with ganciclovir in 183 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 85 (46.45) | 18.2507 |
| 2000's | 65 (35.52) | 29.6817 |
| 2010's | 32 (17.49) | 24.3611 |
| 2020's | 1 (0.55) | 2.80 |
| Authors | Studies |
|---|---|
| Balzarini, J; De Clercq, E; Naesens, L; Neyts, J | 1 |
| Holy, A; Leonhardt, JA; Mead, JR; Morris, JL; Sidwell, RW; Smee, DF | 1 |
| Kern, ER; Patel, P; Simecka, JW | 1 |
| Kern, ER | 1 |
| Andrei, G; De Clercq, E; Neyts, J; Schols, D; Snoeck, R | 1 |
| De Castro, LM; De Clercq, E; Gangemi, JD; Ghaffar, A; Kern, ER; Mayer, EP; Vogt, PE | 1 |
| Balzarini, J; De Clercq, E; Neyts, J; Snoeck, R | 1 |
| De Clercq, E; Himpens, B; Neyts, J; Schols, D; Snoeck, R | 1 |
| Baba, M; De Clercq, E; Konno, K; Shigeta, S; Yokota, T | 1 |
| Datema, R; Yang, H | 1 |
| Balzarini, J; Bron, D; De Clercq, E; Delforge, A; Lagneaux, L; Snoeck, R; Stryckmans, P; Van der Auwera, P | 1 |
| Balzarini, J; De Clercq, E; Neyts, J; Schols, D; Snoeck, R | 1 |
| Chatterjee, S; Gangopadhyay, NN; Whitley, RJ | 1 |
| Cohen, J | 1 |
| Masur, H; Polis, MA | 1 |
| Barnett, BB; Holy, A; Reist, EJ; Sidwell, RW; Smee, DF | 1 |
| De Clercq, E; Neyts, J | 1 |
| Bergeron-Lynn, G; Chandler, B; De Clercq, E; Flores-Aguilar, M; Freeman, WR; Huang, JS; Munguia, D; Vuong, C; Wiley, CA | 1 |
| Bruggeman, CA; de Clercq, E; Havennith, M; Stals, FS; Zeytinoglu, A | 1 |
| Bruggeman, CA; de Clercq, E; Havenith, M; Stals, FS; Zeytinoglu, A | 1 |
| De Clercq, E; Neyts, J; Snoeck, R; Sobis, H; Vandeputte, M | 1 |
| De Clercq, E | 1 |
| Balzarini, J; De Clercq, E; Dvoráková, H; Holý, A; Naesens, L; Reymen, D | 1 |
| Jabs, DA | 1 |
| Freeman, WR | 1 |
| Flaherty, JF | 1 |
| Danner, SA | 1 |
| Chatterjee, S; Lakeman, F; Nii, S; Whitley, RJ; Yamada, M; Yoshida, M | 1 |
| De Clercq, E; Kodama, E; Shigeta, S; Suzuki, T | 1 |
| Reusser, P | 1 |
| Bosmans, E; Bron, D; De Clereq, E; Delforge, A; Lagneaux, L; Schols, D; Snoeck, R; Stryckmans, P | 1 |
| Schwartz, DM | 1 |
| Barnett, BB; Sidwell, RW; Smee, DF | 1 |
| Freytag, SO; Kim, JH; Kim, SH; Rogulski, KR | 1 |
| Hardy, WD | 1 |
| Kuppermann, BD | 1 |
| Cunningham, ET | 1 |
| Eizuru, Y; Harada, K; Ihara, S; Isashiki, Y; Minamishima, Y | 1 |
| Ganem, D; Kedes, DH | 1 |
| Cherrington, JM; Freeman, WR; Fuller, MD; Jiles, RE; Smith, IL; Spector, SA | 1 |
| Jacobson, MA | 1 |
| Okleberry, KM; Smee, DF; Warren, RP | 1 |
| Bruggeman, CA; Kloover, JS; Stals, FS; Vanagt, WY | 1 |
| Chou, S; Drew, WL; Follansbee, SE; Guentzel, S; Lalezari, JP; Marousek, G; Miner, RC; Poscher, ME | 1 |
| Horvath, E; Lund, T; Medveczky, MM; Medveczky, PG | 1 |
| Katlama, C | 1 |
| Pérez, JL | 1 |
| De Clercq, E; Neyts, J; Pagano, JS; Raab-Traub, N; Sadler, R | 1 |
| Takahashi, K | 1 |
| Ai, E; Freeman, WR; Mueller, AJ; Powell, HC; Rahhal, FM; Smith, IL; Spector, SA; Taskintuna, I | 1 |
| Smith, CL | 1 |
| Baldanti, F; Biron, KK; Gerna, G | 1 |
| Pau, AK | 1 |
| Behnsch, M; Bergmann, F; Grobusch, MP; Liekfeld, A; Schürmann, D | 1 |
| Benson, CA; Deutsch, TA; Dieterich, DT; Drew, WL; Feinberg, J; Friedberg, DN; Griffiths, PD; Hardy, WD; Holland, GN; Jabs, DA; Jacobson, MA; Kessler, HA; Polis, MA; Powderly, WG; Spector, SA; Walmsley, S; Whitley, RJ | 1 |
| Cherrington, JM; Cihlar, T; Fuller, MD | 1 |
| Cinatl, J; Scholz, M; Vogel, JU | 1 |
| Cherrington, JM; Cihlar, T; Fuller, MD; Mulato, AS | 1 |
| Aissa, N; Carquin, J; Dewilde, A; Freymuth, F; Houhou-Fidouh, N; Mazeron, MC; Scieux, C; Thouvenot, D | 1 |
| Dunn, JP; Enger, C; Forman, M; Hubbard, L; Jabs, DA | 1 |
| Freeman, WR; Garcia, CR; Torriani, FJ | 1 |
| Cherrington, JM; Drew, WL; Fuller, MD; Lalezari, JP; Lamy, PD; Miner, R; Nuessle, S | 1 |
| Bolton, SG; Dunn, JP; Jabs, DA; Palestine, AG | 1 |
| Cheung, TW; Teich, SA | 1 |
| Cherrington, J; Holtzer, C; Jacobson, MA; Safrin, S; Stanley, H; Wilson, S | 1 |
| Barbeau, D; Bedard, J; Bowlin, TL; May, S; Rando, RF; Yuen, L | 1 |
| Skiest, DJ | 1 |
| Balzarini, J; de Clercq, E; de Vries, E; Franssen, FF; Holý, A; Naesens, L; Overdulve, JP; Smeijsters, LJ | 1 |
| Bowen, EF; Cherrington, JM; Emery, VC; Griffiths, PD; Johnson, MA; Lamy, PD | 1 |
| Drew, WL; Lalezari, JP | 1 |
| Hoy, J | 1 |
| Keating, MR | 1 |
| Au Eong, KG; Beatty, S; Charles, SJ | 1 |
| Blaheta, RA; Cinatl, J; Doerr, HW; Gümbel, HO; Kotchetkov, R; Scholz, M; Vogel, JU; Weimer, E | 1 |
| Bolger, G; Bousquet, C; Cordingley, M; Garneau, M; Kibler, P; Lapeyre, N; Rhéaume, M | 1 |
| Emery, VC | 2 |
| Agut, H; Debré, P; Gautheret-Dejean, A; Grenot, P; Huraux, JM; Manichanh, C | 1 |
| Einsele, H; Hebart, H | 1 |
| Althaus, C; Best, J; Gantke, B; Kersten, A; Theisen, A | 1 |
| Hoffman, VF; Skiest, DJ | 1 |
| Chou, S; Drew, WL; Miner, RC | 1 |
| Distler, A; Ketteler, M; Mertz, A; Offermann, G; Preuschof, L; Schäfer, H; Stöffler-Meilicke, M | 1 |
| Eizuru, Y; Minamishima, Y; Minematsu, T; Mori, S | 1 |
| Boeckh, M; Chuang, EL; Corey, L; Crippa, F; Sale, G | 1 |
| LaBree, L; McDonnell, PJ; Moreira, LB; Oliveira, C; Seitz, B | 1 |
| Castagnola, E; Cristina, E; Dallorso, S; Giacchino, R; Lanino, E | 1 |
| Lawson, CM; Lenzo, JC; Shellam, GR | 1 |
| Blanchet, KD | 1 |
| Torres, G | 2 |
| Cheng, B | 1 |
| Feinberg, J | 1 |
| Highleyman, L | 1 |
| Lee, TA; Malinverni, R; Pleil, AM; Ramsey, SD; Steger, PJ; Sullivan, SD; Veenstra, DL; Williamson, T | 1 |
| Basara, N; Kiehl, MG | 1 |
| Castagnola, E; Chierici, M; Cristina, E; Lanino, E; Miano, M; Morreale, G | 1 |
| Alkan, S; Bhorade, SM; Garrity, ER; Husain, AN; McCabe, MA; Norwick, L; Sandesara, C; Vigneswaran, WT; Yeldandi, V | 1 |
| Boulad, F; Cihlar, T; George, D; Kiehn, TE; Lin, DC; Polsky, B; Prasad, VK; Regan, A; Seo, SK | 1 |
| Bidanset, DJ; Hartline, CB; Kern, ER; Rybak, RJ | 2 |
| Salmon-Ceron, D | 1 |
| De Clercq, E; Naesens, L | 1 |
| Chou, SW | 1 |
| Williams, IG | 1 |
| Di Perri, G; Maiello, A; Quario, M; Racca, D; Sinicco, A; Zeme, DA | 1 |
| Kimberlin, DW | 1 |
| Zaia, JA | 2 |
| Mitchell, SM; Obi, AA; Zambarakji, HJ | 1 |
| Emery, VC; Leśnikowski, ZJ; Olejniczak, A; Paradowska, E; Przepiórkiewicz, M | 1 |
| Bidanset, DJ; Kern, ER; Kushner, NL; Long, MC; Williams, SL | 1 |
| Bakker, HI; De Boer, FM; Harmsen, MC; Meijer, DK; Molema, G; van der Strate, BW | 1 |
| Boivin, G; Sergerie, Y | 1 |
| Boeckh, M; Nichols, WG; Papanicolaou, G; Rubin, R; Wingard, JR; Zaia, J | 1 |
| Baldanti, F; Campanini, G; Comolli, G; Gerna, G; Lilleri, D; Ridolfo, AL; Rusconi, S | 1 |
| Eksborg, S | 1 |
| Alain, S; Belloc, S; Brouet, JC; Ducancelle, A; Malphettes, M; Mazeron, MC; Petit, F; Sanson Le Pors, MJ; Scieux, C | 1 |
| Dunn, JP; Foster, G; Jabs, DA; Kuppermann, BD; Martin, DF; Van Natta, M; Zong, A | 1 |
| Clarke, HE; Maggs, DJ | 1 |
| Clark, DA; Emery, VC; Fryer, JF; Griffiths, PD | 1 |
| De Clercq, E; Friedrichs, C; Gaspar, G; Neyts, J; Wutzler, P | 1 |
| Baldanti, F; Gerna, G; Lurain, N | 1 |
| Alain, S; Denes, E; Magy, L; Pradeau, K; Ranger-Rogez, S; Weinbreck, P | 1 |
| Ljungman, P | 1 |
| Freitag, M; Herget, T; Kupfer, R; Marschall, M; Morbitzer, M; Stamminger, T | 1 |
| Aldern, K; Beadle, JR; Bessho, K; Bovet, JM; Cheng, L; Freeman, WR; Hostetler, KY; Koh, HJ; Lee, J; Toyoguchi, M | 1 |
| Dediulescu, DF; Dediulescu, L | 1 |
| Morton, CJ; Ng, HL; Parker, MW; Rawlinson, WD; Scott, GM | 1 |
| Buonfrate, D; Cesaro, S; Cusinato, R; Manzardo, C; Mengoli, C; Messina, C; Palù, G; Tridello, G; Zhou, X | 1 |
| Boivin, G; Gilbert, C | 1 |
| Moriuchi, H; Moriuchi, M | 1 |
| Chou, S; Drew, WL; Marousek, GI; Miner, RC | 1 |
| Chou, S; Rawlinson, WD; Scott, GM; Weinberg, A | 1 |
| Croubels, S; De Backer, P; Garré, B; Nauwynck, H; Neyts, J; Nugent, J; van der Meulen, K | 1 |
| Abdelhalim, A; Almyroudis, NG; Battiwalla, M; Becker, J; Elefante, A; McCarthy, A; McCarthy, PL; Paplham, P; Segal, BH; Smith, P | 1 |
| Eizuru, Y | 1 |
| Michaels, MG | 1 |
| Bernstein, DI; Bravo, FJ; Cardin, RD | 1 |
| Chou, S; Marousek, GI | 1 |
| Chou, S; Li, S; Marousek, G; Weinberg, A | 1 |
| Boucher, HW; Torres-Madriz, G | 1 |
| Asano-Mori, Y; Chiba, S; Kako, S; Kanda, Y; Kurokawa, M; Motokura, T; Oshima, K; Shiraki, K; Watanabe, T | 1 |
| Casier, S; Filler, G; Grimmer, J; Moussa, M; Rehman, F; Sharma, AP | 1 |
| Járay, J; Péter, A; Telkes, G; Varga, M | 1 |
| Bunjes, D; Härter, G; Mertens, T; Michel, D; Schreiber, A; Schubert, A | 1 |
| Cowan, MJ; Dvorak, CC; Horn, B; Weintrub, PS | 1 |
| Chou, S; Lurain, NS | 1 |
| Kern, ER; Prichard, MN | 1 |
| Agut, H | 1 |
| Capobianchi, A; Foà, R; Gentile, G; Girmenia, C; Iori, AP; Mauro, FR; Micozzi, A; Torelli, GF | 1 |
| Bowlin, TL; Chou, S; Marousek, G | 1 |
| Chavala, S; Miller, MB; Moss, HB; Say, E | 1 |
| Carmichael, A; Goldsmith, PM; Husain, MM; Middleton, SJ; Zhang, H | 1 |
| Hartline, CB; James, SH; Lanier, ER; Price, NB; Prichard, MN | 1 |
| Fischer, L; Göhring, K; Hamprecht, K; Jahn, G; Laib Sampaio, K | 1 |
| Bastide, C; Bruyère, F; Chandenier, J; Desoubeaux, G; Fourcade, C; Guy, L; Karsenty, G; Lachaud, L; Lavigne, JP; Malavaud, S; Sotto, A | 1 |
| Bowlin, TL; Chou, S; Komazin-Meredith, G; Williams, JD | 1 |
| Boivin, G; Piret, J | 1 |
| Gregg, K; Hakki, M; Kaul, DR | 1 |
| Chou, S; Ercolani, RJ; Lefterova, MI; Pinsky, BA; Sahoo, MK; Strasfeld, LM | 1 |
| Balakrishnan, L; Buller, RM; Capella, C; Dewhurst, S; Spencer, JF; Tollefson, AE; Toth, K; Wold, WS; Ying, B | 1 |
| Griffiths, P; Lumley, S | 1 |
| Black, DH; Brush, LA; Eberle, R; Maxwell, LK; Mccormack, KA; Payton, ME; Ritchey, JW; Wright, G | 1 |
| Iapadre, G; Lasorella, S; Mareri, A; Maresca, M; Nigro, G; Tambucci, R | 1 |
| Fischer, L; Göhring, K; Hamprecht, K; Jahn, G; Sampaio, KL | 1 |
| Alain, S; Andouard, D; Cahen, R; Couvreux, A; Deering, M; Hantz, S; Ligat, G; Mazeron, MC; Pouteil-Noble, C; Viget, N; Yasdanpanah, Y | 1 |
| Chou, S; Ercolani, RJ; Lanier, ER | 1 |
| Fischer, L; Göhring, K; Hamprecht, K; Hofmann, J; Imrich, E; Jahn, G; Sampaio, KL | 1 |
| Choo, DI; Nassar, M; Pordal, A; Quimby, C; Sidell, D; Ward, JA | 1 |
| Agut, H; Bonnafous, P; Gautheret-Dejean, A | 1 |
| Andrei, G; Chen, X; Liu, NN; Schols, D; Snoeck, R; Wen, YN; Wu, QP; Xiang, YH; Zhang, QS; Zhang, ZF; Zhang, ZY | 1 |
| Bruminhent, J; Rotjanapan, P; Watcharananan, SP | 1 |
| Spencer, JF; Tollefson, AE; Toth, K; Wold, WSM; Ying, B | 2 |
| Agrawal, N; Beltran, D; Echenique, IA; Najafian, N; Ramirez-Ruiz, L | 1 |
| Frange, P; Leruez-Ville, M | 1 |
| DeVita, AV; Gentry, BG; Markovich, KC; O'Brien, MS; Selleseth, D; Sethna, P | 1 |
| Bar-On, S; Haynes, RK; Lantsberg, D; Laskov, I; Oiknine-Djian, E; Panet, A; Wolf, DG | 1 |
| Demin, MV; Filatov, FP; Tikhomirov, DS; Tupoleva, TA | 1 |
52 review(s) available for cytosine and ganciclovir
| Article | Year |
|---|---|
Value of animal models to evaluate agents with potential activity against human cytomegalovirus.
Topics: Acyclovir; Animals; Antiviral Agents; Cell Division; Cell Survival; Cells, Cultured; Cidofovir; Cytomegalovirus; Cytomegalovirus Infections; Cytosine; Disease Models, Animal; Fibroblasts; Ganciclovir; Humans; Mice; Organophosphonates; Organophosphorus Compounds; Virus Replication | 1991 |
Promising new treatments for cytomegalovirus retinitis.
Topics: AIDS-Related Opportunistic Infections; Cidofovir; Cytomegalovirus Retinitis; Cytosine; Drug Implants; Foscarnet; Ganciclovir; Humans; Injections, Intralesional; Organophosphonates; Organophosphorus Compounds | 1995 |
Antivirals for the treatment of herpesvirus infections.
Topics: Acyclovir; Antiviral Agents; Belgium; Bromodeoxyuridine; Cidofovir; Cytomegalovirus Infections; Cytosine; Ganciclovir; Guanine; Herpesviridae Infections; Humans; Organophosphonates; Organophosphorus Compounds | 1993 |
Management of cytomegalovirus disease.
Topics: Antiviral Agents; Cidofovir; Cytomegalovirus Infections; Cytosine; Drug Therapy, Combination; Foscarnet; Ganciclovir; HIV Infections; Humans; Organophosphonates; Organophosphorus Compounds | 1995 |
Herpesvirus resistance to antiviral drugs: a review of the mechanisms, clinical importance and therapeutic options.
Topics: 2-Aminopurine; Acyclovir; Antiviral Agents; Cidofovir; Cytosine; Drug Resistance, Microbial; Famciclovir; Foscarnet; Ganciclovir; Guanine; Herpesviridae; Herpesviridae Infections; Humans; Immunocompromised Host; Organophosphonates; Organophosphorus Compounds; Valacyclovir; Valine | 1996 |
New therapies for cytomegalovirus retinitis.
Topics: AIDS-Related Opportunistic Infections; Antiviral Agents; Cidofovir; Cytomegalovirus Retinitis; Cytosine; Drug Administration Routes; Drug Therapy, Combination; Ganciclovir; Humans; Organophosphonates; Organophosphorus Compounds; Treatment Outcome | 1996 |
Management strategies for patients with cytomegalovirus retinitis.
Topics: Administration, Oral; AIDS-Related Opportunistic Infections; Antiviral Agents; Cidofovir; Cytomegalovirus Retinitis; Cytosine; Drug Implants; Drug Interactions; Drug Therapy, Combination; Foscarnet; Ganciclovir; Humans; Infusions, Intravenous; Organophosphonates; Organophosphorus Compounds | 1997 |
Therapeutic options for resistant cytomegalovirus retinitis.
Topics: AIDS-Related Opportunistic Infections; Antiviral Agents; Cidofovir; Cytomegalovirus; Cytomegalovirus Retinitis; Cytosine; Drug Implants; Drug Resistance, Microbial; Drug Therapy, Combination; Foscarnet; Ganciclovir; Humans; Infusions, Intravenous; Organophosphonates; Organophosphorus Compounds; Recurrence; Thionucleotides | 1997 |
Treatment of cytomegalovirus retinitis in patients with the acquired immunodeficiency syndrome.
Topics: Administration, Oral; AIDS-Related Opportunistic Infections; Antiviral Agents; Cidofovir; Cytomegalovirus Retinitis; Cytosine; Drug Implants; Drug Therapy, Combination; Foscarnet; Ganciclovir; Humans; Organophosphonates; Organophosphorus Compounds | 1997 |
Management of CMV retinitis in HIV infected patients.
Topics: AIDS-Related Opportunistic Infections; Antiviral Agents; Cidofovir; Clinical Trials as Topic; Cytomegalovirus Retinitis; Cytosine; Foscarnet; Ganciclovir; Guanine; Humans; Organophosphonates; Organophosphorus Compounds; Prodrugs; Prospective Studies; Recurrence | 1997 |
Resistance to antivirals in human cytomegalovirus: mechanisms and clinical significance.
Topics: Antiviral Agents; Cidofovir; Codon; Cytomegalovirus; Cytomegalovirus Infections; Cytosine; Drug Resistance, Microbial; Foscarnet; Ganciclovir; Genes, Viral; Humans; Nucleic Acid Synthesis Inhibitors; Organophosphonates; Organophosphorus Compounds; Phosphotransferases (Alcohol Group Acceptor); Viral Proteins; Viral Structural Proteins | 1997 |
[Recent advances in antiviral drugs--antiviral agents to HCMV, HHV-6, and HHV-7].
Topics: Antiviral Agents; Cidofovir; Cytomegalovirus; Cytomegalovirus Infections; Cytosine; Drug Resistance, Microbial; Foscarnet; Ganciclovir; Herpesviridae Infections; Herpesvirus 6, Human; Herpesvirus 7, Human; Humans; Nucleic Acid Synthesis Inhibitors; Organophosphonates; Organophosphorus Compounds; Purines; Thymidine Kinase | 1998 |
Local therapy for cytomegalovirus retinitis.
Topics: Administration, Topical; AIDS-Related Opportunistic Infections; Anti-HIV Agents; Antiviral Agents; Cidofovir; Cytomegalovirus Retinitis; Cytosine; Foscarnet; Ganciclovir; Humans; Organophosphonates; Organophosphorus Compounds; Vitreous Body | 1998 |
Treatment of cytomegalovirus diseases.
Topics: Acquired Immunodeficiency Syndrome; Antiviral Agents; Cidofovir; Cytomegalovirus Infections; Cytosine; Drug Resistance, Microbial; Drug Therapy, Combination; Enzyme Inhibitors; Foscarnet; Ganciclovir; Humans; Organophosphonates; Organophosphorus Compounds | 1997 |
Cidofovir in the treatment of cytomegalovirus (CMV) retinitis.
Topics: Antiviral Agents; Cidofovir; Cytomegalovirus Retinitis; Cytosine; Drug Implants; Foscarnet; Ganciclovir; Humans; Injections; Organophosphonates; Organophosphorus Compounds | 1998 |
Cytomegalovirus infection in patients with HIV infection.
Topics: AIDS-Related Opportunistic Infections; Antiviral Agents; Cidofovir; Cytomegalovirus Infections; Cytosine; Foscarnet; Ganciclovir; Humans; Organophosphonates; Organophosphorus Compounds | 1999 |
Cytomegalovirus retinitis in the era of highly active antiretroviral therapy (HAART).
Topics: Antiviral Agents; Biomarkers; Cidofovir; Cytomegalovirus Retinitis; Cytosine; Diagnosis, Differential; Foscarnet; Ganciclovir; Herpesviridae; Humans; Incidence; Organophosphonates; Organophosphorus Compounds; Risk Factors | 1999 |
Cytomegalovirus: disease syndromes and treatment.
Topics: AIDS-Related Opportunistic Infections; Antiviral Agents; Central Nervous System Diseases; Chorioretinitis; Cidofovir; Cytomegalovirus Infections; Cytosine; Drug Resistance; Foscarnet; Ganciclovir; Gastrointestinal Diseases; Humans; Organophosphonates; Organophosphorus Compounds; Pneumonia; Sexually Transmitted Diseases, Viral | 1999 |
Management of CMV infections in HIV-infected patients.
Topics: AIDS-Related Opportunistic Infections; Antiviral Agents; Cidofovir; Cytomegalovirus Retinitis; Cytosine; Foscarnet; Ganciclovir; Humans; Organophosphonates; Organophosphorus Compounds | 1999 |
Antiviral agents for non-human immunodeficiency virus infections.
Topics: 2-Aminopurine; Acetamides; Acyclovir; Amantadine; Antiviral Agents; Cidofovir; Cytosine; Drug Resistance, Microbial; Drugs, Investigational; Enzyme Inhibitors; Famciclovir; Foscarnet; Ganciclovir; Guanidines; Guanine; Humans; Interferons; Lamivudine; Neuraminidase; Organophosphonates; Organophosphorus Compounds; Oseltamivir; Pyrans; Ribavirin; Sialic Acids; Valacyclovir; Valine; Virus Diseases; Zanamivir | 1999 |
Cytomegalovirus retinitis in patients with acquired immune deficiency syndrome.
Topics: Anti-HIV Agents; CD4 Lymphocyte Count; Cidofovir; Cytomegalovirus Retinitis; Cytosine; Foscarnet; Ganciclovir; HIV Infections; Humans; Organophosphonates; Organophosphorus Compounds; Retinal Detachment | 1999 |
Cytomegalovirus drug resistance.
Topics: Antiviral Agents; Cidofovir; Cytomegalovirus Infections; Cytosine; Drug Resistance; Foscarnet; Ganciclovir; Humans; Mutation; Organophosphonates; Organophosphorus Compounds | 1998 |
Cytomegalovirus infection following stem cell transplantation.
Topics: Acyclovir; Antibodies, Viral; Antiviral Agents; Blood Donors; Cidofovir; Cytomegalovirus; Cytomegalovirus Infections; Cytosine; Foscarnet; Ganciclovir; Hematopoietic Stem Cell Transplantation; Hematopoietic Stem Cells; Humans; Immunocompromised Host; Immunotherapy, Adoptive; Leukocyte Transfusion; Organophosphonates; Organophosphorus Compounds; Premedication; Risk Factors; Tissue Donors; Transfusion Reaction; Virus Latency | 1999 |
Therapeutic developments in cytomegalovirus retinitis.
Topics: Adenine; Antibodies, Monoclonal; Antiviral Agents; Cidofovir; Cytomegalovirus Retinitis; Cytosine; Drugs, Investigational; Foscarnet; Ganciclovir; Guanine; Humans; Organophosphonates; Organophosphorus Compounds; Thionucleotides; Valganciclovir | 2000 |
Progress in understanding cytomegalovirus drug resistance.
Topics: Antiviral Agents; Cidofovir; Cytomegalovirus; Cytomegalovirus Infections; Cytosine; Drug Resistance, Microbial; Forecasting; Foscarnet; Ganciclovir; Humans; Incidence; Organophosphonates; Organophosphorus Compounds | 2001 |
Economic evaluation of systemic treatments for cytomegalovirus retinitis in patients with AIDS.
Topics: Adult; AIDS-Related Opportunistic Infections; Antiviral Agents; Cidofovir; Cytomegalovirus Retinitis; Cytosine; Economics, Pharmaceutical; Foscarnet; Ganciclovir; Humans; Models, Economic; Organophosphonates; Organophosphorus Compounds; Switzerland; Treatment Failure | 2001 |
Cytomegalovirus infection: the point in 2001.
Topics: AIDS-Related Opportunistic Infections; Anti-HIV Agents; Antiretroviral Therapy, Highly Active; Antiviral Agents; CD4 Lymphocyte Count; Cidofovir; Cytomegalovirus Infections; Cytosine; Drug Monitoring; Foscarnet; Ganciclovir; Humans; Organophosphonates; Organophosphorus Compounds; Polymerase Chain Reaction; Population Surveillance; Predictive Value of Tests; Prevalence; Risk Factors; Valganciclovir | 2001 |
Recent developments in herpesvirus therapy.
Topics: 2-Aminopurine; Acyclovir; Antiviral Agents; Arabinofuranosyluracil; Bromodeoxyuridine; Cidofovir; Clinical Trials as Topic; Cytosine; Famciclovir; Foscarnet; Ganciclovir; Guanine; Herpesviridae Infections; Humans; Organophosphonates; Organophosphorus Compounds; Thionucleotides; Valacyclovir; Valine | 2001 |
Cytomegalovirus drug resistance and clinical implications.
Topics: Antiviral Agents; Cidofovir; Cytomegalovirus; Cytomegalovirus Infections; Cytosine; Drug Resistance, Viral; Foscarnet; Ganciclovir; Humans; Incidence; Organ Transplantation; Organophosphonates; Organophosphorus Compounds; Risk Factors | 2001 |
Management of CMV disease in HIV infection.
Topics: AIDS-Related Opportunistic Infections; Antiviral Agents; Cidofovir; Cytomegalovirus Infections; Cytomegalovirus Retinitis; Cytosine; Encephalitis, Viral; Foscarnet; Ganciclovir; Gastrointestinal Diseases; Humans; Organophosphonates; Organophosphorus Compounds | 1999 |
Prevention and management of CMV-related problems after hematopoietic stem cell transplantation.
Topics: Acyclovir; Antiviral Agents; Cidofovir; Cytomegalovirus; Cytomegalovirus Infections; Cytosine; Foscarnet; Ganciclovir; Hematopoietic Stem Cell Transplantation; Humans; Organophosphonates; Organophosphorus Compounds; Risk Factors | 2002 |
[Drugs against human cytomegalovirus].
Topics: Acyclovir; AIDS-Related Opportunistic Infections; Antiviral Agents; Cidofovir; Cytomegalovirus Infections; Cytosine; Drugs, Investigational; Female; Foscarnet; Ganciclovir; Global Health; Humans; Infectious Disease Transmission, Vertical; Naphthalenesulfonates; Organophosphonates; Organophosphorus Compounds; Pregnancy; Pregnancy Complications, Infectious; Thionucleotides; Valacyclovir; Valganciclovir; Valine | 2002 |
Cytomegalovirus in hematopoietic stem cell transplant recipients: Current status, known challenges, and future strategies.
Topics: Acyclovir; Antigens, CD34; Antiviral Agents; Cidofovir; Cytomegalovirus Infections; Cytosine; Foscarnet; Ganciclovir; Graft vs Host Disease; Hematopoietic Stem Cell Transplantation; Humans; Immunoglobulins, Intravenous; Immunosuppression Therapy; Immunotherapy; Lymphocyte Depletion; Organophosphonates; Organophosphorus Compounds; Transplantation Conditioning | 2003 |
The pharmacokinetics of antiviral therapy in paediatric patients.
Topics: 2-Aminopurine; Acyclovir; Antiviral Agents; Child; Child, Hospitalized; Cidofovir; Cytosine; Famciclovir; Foscarnet; Ganciclovir; Humans; Organophosphonates; Organophosphorus Compounds; Virus Diseases | 2003 |
Clinical and biologic aspects of human cytomegalovirus resistance to antiviral drugs.
Topics: Acquired Immunodeficiency Syndrome; Antiretroviral Therapy, Highly Active; Cidofovir; Cytomegalovirus; Cytomegalovirus Infections; Cytosine; DNA Mutational Analysis; DNA-Directed DNA Polymerase; Drug Resistance, Viral; Foscarnet; Ganciclovir; Humans; Mutation; Organophosphonates; Phosphotransferases (Alcohol Group Acceptor); Viral Proteins; Virus Replication | 2004 |
Treatment of adenovirus infections in the immunocompromised host.
Topics: Adenoviridae Infections; Antiviral Agents; Cidofovir; Clinical Trials as Topic; Cytosine; Dose-Response Relationship, Drug; Drug Administration Schedule; Female; Ganciclovir; Hematopoietic Stem Cell Transplantation; Humans; Immunocompromised Host; Male; Organ Transplantation; Organophosphonates; Organophosphorus Compounds; Prognosis; Ribavirin; Severity of Illness Index; Transplantation Immunology; Treatment Outcome; Vidarabine | 2004 |
[Antiherpetic therapy].
Topics: 2-Aminopurine; Acyclovir; Antiviral Agents; Bromodeoxyuridine; Cidofovir; Cytosine; Drug Combinations; Famciclovir; Foscarnet; Ganciclovir; Humans; Idoxuridine; Keratitis, Herpetic; Oligonucleotides; Ophthalmic Solutions; Organophosphonates; Treatment Outcome; Valacyclovir; Valine; Vidarabine | 2005 |
[Treatment of HHV-6 and HHV-7 infections].
Topics: Antiviral Agents; Cidofovir; Cytosine; Drug Therapy, Combination; Foscarnet; Ganciclovir; Herpesvirus 6, Human; Herpesvirus 7, Human; Humans; Immunoglobulins; Lymphocyte Transfusion; Organophosphonates; Roseolovirus Infections | 2006 |
[Mechanism of drug-resistance in human cytomegalovirus].
Topics: Antiviral Agents; Cidofovir; Cytomegalovirus; Cytomegalovirus Infections; Cytosine; DNA-Directed DNA Polymerase; Drug Resistance, Microbial; Foscarnet; Ganciclovir; Humans; Mutation; Organophosphonates; Phosphotransferases (Alcohol Group Acceptor); Viral Proteins | 2007 |
Treatment of congenital cytomegalovirus: where are we now?
Topics: Antiviral Agents; Cidofovir; Cytomegalovirus Infections; Cytosine; Female; Foscarnet; Ganciclovir; Humans; Infant, Newborn; Organophosphonates; Pregnancy; Valganciclovir | 2007 |
Immunocompromised hosts: perspectives in the treatment and prophylaxis of cytomegalovirus disease in solid-organ transplant recipients.
Topics: Antiviral Agents; Chemoprevention; Cidofovir; Cytomegalovirus Infections; Cytosine; Drug Resistance, Viral; Foscarnet; Ganciclovir; Humans; Immunocompromised Host; Organ Transplantation; Organophosphonates; Transplantation; Valganciclovir | 2008 |
[Gastrointestinal cytomegalovirus infections in organ transplant patients].
Topics: Acyclovir; Antiviral Agents; Biopsy; Cidofovir; Cytomegalovirus; Cytomegalovirus Infections; Cytosine; Endoscopy, Gastrointestinal; Foscarnet; Ganciclovir; Gastric Mucosa; Gastrointestinal Diseases; Gastrointestinal Tract; Humans; Immunocompromised Host; Immunoglobulins; Immunotherapy, Adoptive; Intestinal Mucosa; Organ Transplantation; Organophosphonates; Primary Prevention; Valganciclovir | 2008 |
Antiviral treatment of cytomegalovirus infection and resistant strains.
Topics: Antiviral Agents; Cidofovir; Cytomegalovirus Infections; Cytosine; Drug Resistance, Viral; Drug Therapy, Combination; Foscarnet; Ganciclovir; Humans; Organophosphonates; Thionucleotides; Valganciclovir | 2009 |
Antiviral drug resistance of human cytomegalovirus.
Topics: Antiviral Agents; Cidofovir; Cytomegalovirus; Cytomegalovirus Infections; Cytosine; DNA-Directed DNA Polymerase; Drug Resistance, Viral; Foscarnet; Ganciclovir; Genome, Viral; Humans; Organophosphonates; Phosphotransferases (Alcohol Group Acceptor); Sequence Analysis, DNA | 2010 |
The search for new therapies for human cytomegalovirus infections.
Topics: Antiviral Agents; Cidofovir; Cyclopropanes; Cytomegalovirus; Cytomegalovirus Infections; Cytosine; Foscarnet; Ganciclovir; Guanine; Humans; Organophosphonates; Valganciclovir; Virus Replication | 2011 |
Deciphering the clinical impact of acute human herpesvirus 6 (HHV-6) infections.
Topics: Antiviral Agents; Child; Child, Preschool; Cidofovir; Cytosine; DNA, Viral; Foscarnet; Ganciclovir; Herpesvirus 6, Human; Humans; Immunity, Cellular; Infant; Organophosphonates; Roseolovirus Infections; Viral Load; Virus Latency | 2011 |
[Non-antibiotic anti-infectious treatments in urology].
Topics: Acyclovir; Albendazole; Amphotericin B; Anti-Infective Agents; Caspofungin; Cidofovir; Cytosine; Echinocandins; Fluconazole; Flucytosine; Foscarnet; Ganciclovir; Humans; Ivermectin; Lipopeptides; Organophosphonates; Praziquantel; Urologic Diseases; Valganciclovir | 2013 |
Antiviral drug resistance in herpesviruses other than cytomegalovirus.
Topics: Acyclovir; Antiviral Agents; Cidofovir; Cytomegalovirus; Cytosine; Drug Resistance, Viral; Foscarnet; Ganciclovir; Herpesviridae Infections; Herpesvirus 1, Human; Herpesvirus 2, Human; Herpesvirus 3, Human; Herpesvirus 6, Human; Humans; Immunocompromised Host; Organophosphonates | 2014 |
Cytomegalovirus.
Topics: Acetates; Antiviral Agents; Benzimidazoles; Bone Marrow Transplantation; Cytomegalovirus; Cytomegalovirus Infections; Cytosine; Disease Transmission, Infectious; Double-Blind Method; Female; Ganciclovir; Humans; Male; Organ Transplantation; Organophosphonates; Practice Guidelines as Topic; Pregnancy; Pregnancy Complications, Infectious; Quinazolines; Randomized Controlled Trials as Topic; Ribonucleosides | 2014 |
Anti-viral therapy for congenital cytomegalovirus infection: pharmacokinetics, efficacy and side effects.
Topics: Antiviral Agents; Cidofovir; Cytomegalovirus Infections; Cytosine; Foscarnet; Ganciclovir; Humans; Immunocompetence; Organophosphonates; Treatment Outcome | 2016 |
Human Herpesviruses 6A, 6B, and 7.
Topics: Antiviral Agents; Cidofovir; Cytosine; DNA, Viral; Foscarnet; Ganciclovir; Herpesvirus 6, Human; Herpesvirus 7, Human; Humans; Immunocompromised Host; Organophosphonates; Roseolovirus Infections; Transplant Recipients; Virus Latency | 2016 |
Maribavir, brincidofovir and letermovir: Efficacy and safety of new antiviral drugs for treating cytomegalovirus infections.
Topics: Acetates; Antiviral Agents; Benzimidazoles; Cytomegalovirus Infections; Cytosine; Ganciclovir; Humans; Organophosphonates; Quinazolines; Ribonucleosides | 2018 |
6 trial(s) available for cytosine and ganciclovir
| Article | Year |
|---|---|
Phase I study of combination therapy with intravenous cidofovir and oral ganciclovir for cytomegalovirus retinitis in patients with AIDS.
Topics: Adult; AIDS-Related Opportunistic Infections; Antiviral Agents; Cidofovir; Cytomegalovirus Retinitis; Cytosine; Drug Therapy, Combination; Female; Ganciclovir; Humans; Male; Middle Aged; Organophosphonates; Organophosphorus Compounds; Treatment Outcome | 1999 |
The ganciclovir implant plus oral ganciclovir versus parenteral cidofovir for the treatment of cytomegalovirus retinitis in patients with acquired immunodeficiency syndrome: The Ganciclovir Cidofovir Cytomegalovirus Retinitis Trial.
Topics: Administration, Oral; Adult; AIDS-Related Opportunistic Infections; Antiviral Agents; Cidofovir; Cytomegalovirus Retinitis; Cytosine; Disease Progression; Double-Blind Method; Drug Evaluation; Drug Implants; Female; Ganciclovir; Humans; Infusions, Parenteral; Kidney; Male; Organophosphonates; Organophosphorus Compounds; Survival Rate; Treatment Outcome; Uveitis; Visual Acuity; Vitreous Hemorrhage | 2001 |
Update on treatment of CMV retinitis.
Topics: Administration, Oral; AIDS-Related Opportunistic Infections; Cidofovir; Cytomegalovirus Retinitis; Cytosine; Drug Implants; Eye; Ganciclovir; Humans; Infusions, Intravenous; Organophosphonates; Organophosphorus Compounds; Randomized Controlled Trials as Topic | 1995 |
Opportunistic infection highlights from the 35th ICAAC.
Topics: Acyclovir; AIDS-Related Opportunistic Infections; Antiviral Agents; Bacterial Vaccines; CD4 Lymphocyte Count; Cidofovir; Clinical Trials as Topic; Cytomegalovirus Infections; Cytosine; Drug Resistance, Microbial; Ganciclovir; HIV; Humans; Influenza Vaccines; Mycobacterium avium-intracellulare Infection; Organophosphonates; Organophosphorus Compounds; Pneumonia; Pneumonia, Pneumocystis; Randomized Controlled Trials as Topic; United States; Valacyclovir; Valine; Viremia | 1995 |
Cidofovir for cytomegalovirus-preemptive therapy in stem cell transplant recipients.
Topics: Antiviral Agents; Cidofovir; Cytomegalovirus; Cytomegalovirus Infections; Cytosine; Drug Resistance, Microbial; Drug Therapy, Combination; Foscarnet; Ganciclovir; Hematologic Neoplasms; Hematopoietic Stem Cell Transplantation; Humans; Myelodysplastic Syndromes; Organophosphonates; Organophosphorus Compounds; Prospective Studies; Transplantation, Homologous; Treatment Failure; Viremia; Virus Activation | 2001 |
Complications of ganciclovir implant surgery in patients with cytomegalovirus retinitis: the Ganciclovir Cidofovir Cytomegalovirus Retinitis Trial.
Topics: Administration, Oral; Adult; AIDS-Related Opportunistic Infections; Anesthesia, General; Anesthesia, Local; Antiviral Agents; Cidofovir; Cytomegalovirus Retinitis; Cytosine; Drug Implants; Female; Ganciclovir; Humans; Infusions, Intravenous; Intraoperative Complications; Male; Organophosphonates; Organophosphorus Compounds; Postoperative Complications; Prospective Studies; Visual Acuity; Vitreous Hemorrhage | 2004 |
125 other study(ies) available for cytosine and ganciclovir
| Article | Year |
|---|---|
Efficacy of (S)-1-(3-hydroxy-2-phosphonylmethoxypropyl)cytosine and 9-(1,3-dihydroxy-2-propoxymethyl)guanine for the treatment of murine cytomegalovirus infection in severe combined immunodeficiency mice.
Topics: Animals; Antiviral Agents; Cidofovir; Cytomegalovirus Infections; Cytosine; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Administration Schedule; Female; Ganciclovir; Male; Mice; Mice, SCID; Organophosphonates; Organophosphorus Compounds | 1992 |
Treatment of murine cytomegalovirus infections in severe combined immunodeficient mice with ganciclovir, (S)-1-[3-hydroxy-2-(phosphonylmethoxy)propyl]cytosine, interferon, and bropirimine.
Topics: Animals; Antifungal Agents; Antineoplastic Agents; Cidofovir; Cytomegalovirus Infections; Cytosine; Disease Models, Animal; Drug Combinations; Ganciclovir; Immunologic Deficiency Syndromes; Interferon Type I; Mice; Mice, Inbred BALB C; Mice, Inbred Strains; Organophosphonates; Organophosphorus Compounds; Recombinant Proteins | 1992 |
Immunotoxic potential of antiviral drugs: effects of ganciclovir and (S)-1-(3-hydroxy-2-phosphonylmethoxy propyl) cytosine on lymphocyte transformation and delayed-type hypersensitivity responses.
Topics: Animals; Antiviral Agents; Cell Survival; Cidofovir; Concanavalin A; Cytosine; Ganciclovir; Humans; Hypersensitivity, Delayed; In Vitro Techniques; Lymphocyte Activation; Lymphocytes; Mice; Mice, Inbred C3H; Organophosphonates; Organophosphorus Compounds; Phytohemagglutinins; Specific Pathogen-Free Organisms | 1992 |
Antiviral activity of anti-cytomegalovirus agents (HPMPC, HPMPA) assessed by a flow cytometric method and DNA hybridization technique.
Topics: Adenine; Antiviral Agents; Cell Line; Cidofovir; Cytomegalovirus; Cytosine; Flow Cytometry; Ganciclovir; Humans; Microbial Sensitivity Tests; Nucleic Acid Hybridization; Organophosphonates; Organophosphorus Compounds; Viral Plaque Assay | 1991 |
Phosphonylmethoxyalkyl purine and pyrimidine derivatives for treatment of opportunistic cytomegalovirus and herpes simplex virus infections in murine AIDS.
Topics: Adenine; Animals; Antiviral Agents; Cidofovir; Cytomegalovirus Infections; Cytosine; Ganciclovir; Herpes Simplex; Immune Tolerance; Mice; Mice, Inbred C57BL; Murine Acquired Immunodeficiency Syndrome; Opportunistic Infections; Organophosphonates; Organophosphorus Compounds | 1991 |
Particular characteristics of the anti-human cytomegalovirus activity of (S)-1-(3-hydroxy-2-phosphonylmethoxypropyl)cytosine (HPMPC) in vitro.
Topics: Animals; Antiviral Agents; Cidofovir; Cytarabine; Cytidine; Cytomegalovirus; Cytosine; Deoxycytidine; DNA, Viral; Ganciclovir; Humans; Organophosphonates; Organophosphorus Compounds; Tumor Cells, Cultured; Virus Replication | 1991 |
Sensitive, reproducible and convenient fluorometric assay for the in vitro evaluation of anti-cytomegalovirus agents.
Topics: Acyclovir; Antiviral Agents; Cidofovir; Cytomegalovirus; Cytomegalovirus Infections; Cytosine; Esterases; Flow Cytometry; Fluoresceins; Fluorometry; Foscarnet; Ganciclovir; Humans; Microbial Sensitivity Tests; Organophosphonates; Organophosphorus Compounds; Phosphonoacetic Acid; Polyethylene Glycols; Suramin | 1991 |
Comparative inhibitory effects of nucleoside analogues on different clinical isolates of human cytomegalovirus in vitro.
Topics: Adenine; Adenosine; Antiviral Agents; Cell Line; Cidofovir; Cytidine; Cytomegalovirus; Cytosine; Ganciclovir; Guanosine; Humans; Nucleosides; Organophosphonates; Organophosphorus Compounds; Thymidine | 1991 |
Prolonged and potent therapeutic and prophylactic effects of (S)-1-[(3-hydroxy-2-phosphonylmethoxy)propyl]cytosine against herpes simplex virus type 2 infections in mice.
Topics: Animals; Antiviral Agents; Brain Stem; Cidofovir; Cytosine; Drug Administration Schedule; Encephalitis; Female; Ganciclovir; Herpes Simplex; Mice; Organophosphonates; Organophosphorus Compounds; Premedication | 1991 |
Inhibitory effects of potent inhibitors of human immunodeficiency virus and cytomegalovirus on the growth of human granulocyte-macrophage progenitor cells in vitro.
Topics: Adenine; Adult; Antiviral Agents; Bone Marrow; Bone Marrow Cells; Cells, Cultured; Cidofovir; Cytomegalovirus; Cytosine; Foscarnet; Ganciclovir; Granulocytes; Hematopoietic Stem Cells; HIV; Humans; Macrophages; Organophosphonates; Organophosphorus Compounds; Phosphonoacetic Acid; Zidovudine | 1990 |
Selective inhibition of human cytomegalovirus DNA synthesis by (S)-1-(3-hydroxy-2-phosphonylmethoxypropyl)cytosine [(S)-HPMPC] and 9-(1,3-dihydroxy-2-propoxymethyl)guanine (DHPG).
Topics: Antiviral Agents; Cell Line; Cell Survival; Cidofovir; Cytomegalovirus; Cytosine; DNA; DNA Replication; DNA, Viral; Flow Cytometry; Ganciclovir; Humans; Organophosphonates; Organophosphorus Compounds | 1990 |
A rapid protein A binding radioimmunoassay for the evaluation of antiviral agents.
Topics: Antiviral Agents; Cells, Cultured; Cidofovir; Cytomegalovirus; Cytosine; Evaluation Studies as Topic; Ganciclovir; Humans; Interferons; Microbial Sensitivity Tests; Organophosphonates; Organophosphorus Compounds; Radioimmunoassay; Staphylococcal Protein A; Time Factors; Virus Replication | 1994 |
AIDS therapy. New hope against blindness.
Topics: AIDS-Related Opportunistic Infections; Antiviral Agents; Blindness; Cidofovir; Clinical Trials as Topic; Cytomegalovirus Retinitis; Cytosine; Drug Implants; Ganciclovir; Humans; Organophosphonates; Organophosphorus Compounds; RNA, Antisense | 1995 |
Antiviral activities of nucleosides and nucleotides against wild-type and drug-resistant strains of murine cytomegalovirus.
Topics: Acyclovir; Animals; Antiviral Agents; Cidofovir; Cytosine; Drug Resistance, Microbial; Foscarnet; Ganciclovir; Guanine; Herpesviridae Infections; Mice; Mice, SCID; Microbial Sensitivity Tests; Muromegalovirus; Nucleosides; Nucleotides; Organophosphonates; Organophosphorus Compounds | 1995 |
New inhibitors of cytomegalovirus replication: in vitro evaluation, mechanism of action, and in vivo activity.
Topics: Adenine; Animals; Antiviral Agents; Cidofovir; Cytomegalovirus; Cytomegalovirus Infections; Cytosine; DNA, Viral; Ganciclovir; Herpesviridae Infections; Humans; Immunologic Deficiency Syndromes; Mice; Mice, SCID; Muromegalovirus; Organophosphonates; Organophosphorus Compounds; Virus Replication | 1994 |
Long-acting therapy of viral retinitis with (S)-1-(3-hydroxy-2-phosphonylmethoxypropyl)cytosine.
Topics: Animals; Antiviral Agents; Cidofovir; Cytosine; Drug Therapy, Combination; Ganciclovir; Herpes Simplex; Herpesvirus 1, Human; Organophosphonates; Organophosphorus Compounds; Rabbits; Retinitis; Time Factors | 1994 |
Comparative effect of (S)-1-(3-hydroxy-2-phosphonylmethoxypropyl)cytosine and 9-(1,3-dihydroxy-2-propoxymethyl)guanine treatment on cytomegalovirus-induced interstitial pneumonitis in allogeneic bone marrow transplant recipient rats.
Topics: Animals; Antiviral Agents; Bone Marrow Transplantation; Cidofovir; Cytomegalovirus Infections; Cytosine; Ganciclovir; Male; Organophosphonates; Organophosphorus Compounds; Pulmonary Fibrosis; Rats; Rats, Inbred BN; Rats, Inbred Lew; Transplantation, Homologous; Whole-Body Irradiation | 1993 |
Rat cytomegalovirus-induced pneumonitis after allogeneic bone marrow transplantation: effective treatment with (S)-1-(3-hydroxy-2-phosphonyl-methoxypropyl)cytosine.
Topics: Animals; Antigens, Viral; Antiviral Agents; Bone Marrow Transplantation; Cidofovir; Cytomegalovirus; Cytomegalovirus Infections; Cytosine; Disease Models, Animal; Ganciclovir; Immunohistochemistry; Lung; Male; Organophosphonates; Organophosphorus Compounds; Paraffin Embedding; Pneumonia, Viral; Rats; Whole-Body Irradiation | 1993 |
Efficacy of (S)-1-(3-hydroxy-2-phosphonylmethoxypropyl)-cytosine and 9-(1,3-dihydroxy-2-propoxymethyl)-guanine in the treatment of intracerebral murine cytomegalovirus infections in immunocompetent and immunodeficient mice.
Topics: Animals; Animals, Newborn; Antiviral Agents; Brain; Brain Diseases; Cidofovir; Cytomegalovirus; Cytomegalovirus Infections; Cytosine; Dose-Response Relationship, Drug; Ganciclovir; Mice; Mice, SCID; Organophosphonates; Organophosphorus Compounds | 1993 |
Antiviral activity of selected acyclic nucleoside analogues against human herpesvirus 6.
Topics: Adenine; Antiviral Agents; Cell Line; Cidofovir; Cytopathogenic Effect, Viral; Cytosine; Flow Cytometry; Foscarnet; Ganciclovir; Herpesvirus 6, Human; Humans; Nucleosides; Organophosphonates; Organophosphorus Compounds | 1995 |
Treatment of cytomegalovirus retinitis in patients with AIDS.
Topics: AIDS-Related Opportunistic Infections; Antiviral Agents; Cidofovir; Cytomegalovirus Infections; Cytosine; Drug Administration Routes; Foscarnet; Ganciclovir; Humans; Organophosphonates; Organophosphorus Compounds; Retinitis | 1996 |
New developments in the treatment of CMV retinitis.
Topics: AIDS-Related Opportunistic Infections; Antiviral Agents; Cidofovir; Cytomegalovirus Retinitis; Cytosine; Foscarnet; Ganciclovir; Humans; Injections; Injections, Intravenous; Organophosphonates; Organophosphorus Compounds; Vitreous Body | 1996 |
Current and experimental therapeutic options for cytomegalovirus disease.
Topics: Administration, Oral; Antiviral Agents; Cidofovir; Cytomegalovirus; Cytomegalovirus Infections; Cytomegalovirus Retinitis; Cytosine; Delayed-Action Preparations; Foscarnet; Ganciclovir; Guanine; Humans; Injections, Intravenous; Organophosphonates; Organophosphorus Compounds | 1996 |
A method for detection of HHV-6 antigens and its use for evaluating antiviral drugs.
Topics: Antigens, Viral; Antiviral Agents; Cidofovir; Cytosine; Drug Evaluation; Foscarnet; Ganciclovir; Herpesvirus 6, Human; Humans; Organophosphonates; Organophosphorus Compounds; Reproducibility of Results | 1996 |
Application of a gastric cancer cell line (MKN-28) for anti-adenovirus screening using the MTT method.
Topics: Adenine; Adenoviruses, Human; Antiviral Agents; Cidofovir; Cytosine; Drug Evaluation, Preclinical; Formazans; Ganciclovir; Humans; Idoxuridine; Organophosphonates; Organophosphorus Compounds; Purines; Stomach Neoplasms; Tetrazolium Salts; Thiazoles; Tumor Cells, Cultured | 1996 |
Imbalance in production of cytokines by bone marrow stromal cells following cytomegalovirus infection.
Topics: Bone Marrow Cells; Cidofovir; Cytokines; Cytomegalovirus; Cytosine; Ganciclovir; Humans; Lipopolysaccharides; Organophosphonates; Organophosphorus Compounds; Stromal Cells; Virus Replication | 1996 |
Combination of antiviral immunotoxin and ganciclovir or cidofovir for the treatment of murine cytomegalovirus infections.
Topics: Animals; Antiviral Agents; Cidofovir; Cytomegalovirus Infections; Cytosine; Drug Therapy, Combination; Ganciclovir; Immunotoxins; Mice; Mice, SCID; Muromegalovirus; Organophosphonates; Organophosphorus Compounds; Plant Proteins; Ribosome Inactivating Proteins, Type 1; Ricin; Tumor Cells, Cultured | 1996 |
Glioma cells transduced with an Escherichia coli CD/HSV-1 TK fusion gene exhibit enhanced metabolic suicide and radiosensitivity.
Topics: Blotting, Western; Bromodeoxyuridine; Cytosine; Cytosine Deaminase; Deoxyuridine; Enzyme Inhibitors; Escherichia coli; Flucytosine; Ganciclovir; Gene Expression Regulation, Viral; Gene Transfer Techniques; Genetic Therapy; Genetic Vectors; Gliosarcoma; Humans; Nucleoside Deaminases; Prodrugs; Radiation Tolerance; Recombinant Fusion Proteins; Simplexvirus; Thymidine Kinase; Tumor Cells, Cultured | 1997 |
New therapies for cytomegalovirus retinitis in patients with the acquired immunodeficiency syndrome.
Topics: AIDS-Related Opportunistic Infections; Antiviral Agents; Cidofovir; Cytomegalovirus Infections; Cytosine; Foscarnet; Ganciclovir; Humans; Organophosphonates; Organophosphorus Compounds; Prognosis; Retinitis | 1997 |
Genetic analysis of a clinical isolate of human cytomegalovirus exhibiting resistance against both ganciclovir and cidofovir.
Topics: Antiviral Agents; Cidofovir; Cytomegalovirus; Cytomegalovirus Infections; Cytosine; DNA, Viral; Drug Resistance, Microbial; Ganciclovir; Humans; Mutation; Organophosphonates; Organophosphorus Compounds; Sequence Analysis, DNA | 1997 |
Sensitivity of Kaposi's sarcoma-associated herpesvirus replication to antiviral drugs. Implications for potential therapy.
Topics: Acyclovir; Antiviral Agents; Cidofovir; Cytosine; DNA Probes; DNA, Viral; Foscarnet; Ganciclovir; Herpesvirus 8, Human; HIV Protease Inhibitors; Humans; Methylurea Compounds; Nucleic Acid Hybridization; Organophosphonates; Organophosphorus Compounds; Phorbol Esters; Pyridines; Sarcoma, Kaposi; Tumor Cells, Cultured; Valine; Virus Replication | 1997 |
High-level resistance of cytomegalovirus to ganciclovir is associated with alterations in both the UL97 and DNA polymerase genes.
Topics: Antiviral Agents; Cidofovir; Cytomegalovirus; Cytosine; DNA-Directed DNA Polymerase; Drug Resistance; Ganciclovir; Humans; Mutation; Organophosphonates; Organophosphorus Compounds; Phosphotransferases (Alcohol Group Acceptor) | 1997 |
Metabolism of ganciclovir and cidofovir in cells infected with drug-resistant and wild-type strains of murine cytomegalovirus.
Topics: Animals; Antiviral Agents; Cidofovir; Cytosine; Drug Resistance, Microbial; Ganciclovir; Mice; Muromegalovirus; Organophosphonates; Organophosphorus Compounds; Phosphorylation; Time Factors; Tumor Cells, Cultured | 1997 |
Effective treatment of experimental cytomegalovirus-induced encephalo-meningitis in immunocompromised rats with HPMPC.
Topics: Animals; Antiviral Agents; Brain; Cidofovir; Cytomegalovirus Infections; Cytosine; Disease Models, Animal; Drug Therapy, Combination; Ganciclovir; Immune Sera; Immunocompromised Host; Male; Meninges; Meningitis, Viral; Organophosphonates; Organophosphorus Compounds; Rats; Rats, Inbred BN; Time Factors | 1997 |
Drugs for non-HIV viral infections.
Topics: 2-Aminopurine; Abnormalities, Drug-Induced; Acyclovir; Amantadine; Antiviral Agents; Cidofovir; Contraindications; Cytosine; Drug Resistance, Microbial; Eye Infections, Viral; Famciclovir; Foscarnet; Ganciclovir; Guanine; Humans; Interferon-alpha; Kidney Diseases; Lamivudine; Organophosphonates; Organophosphorus Compounds; Prodrugs; Ribavirin; Rimantadine; Trifluridine; Valacyclovir; Valine; Virus Diseases | 1997 |
Evolution of mutations conferring multidrug resistance during prophylaxis and therapy for cytomegalovirus disease.
Topics: Adult; AIDS-Related Opportunistic Infections; Anti-HIV Agents; Antiviral Agents; Cidofovir; Cytomegalovirus; Cytomegalovirus Infections; Cytosine; Drug Resistance, Microbial; Drug Resistance, Multiple; Drug Therapy, Combination; Foscarnet; Ganciclovir; Humans; Male; Mutation; Organophosphonates; Organophosphorus Compounds; Phosphotransferases (Alcohol Group Acceptor); Recombination, Genetic; RNA-Directed DNA Polymerase; Sequence Analysis, DNA | 1997 |
In vitro antiviral drug sensitivity of the Kaposi's sarcoma-associated herpesvirus.
Topics: Acyclovir; Antiviral Agents; Carcinogens; Cidofovir; Cytosine; DNA-Directed DNA Polymerase; DNA, Viral; Foscarnet; Ganciclovir; Herpesvirus 8, Human; Humans; Microbial Sensitivity Tests; Organophosphonates; Organophosphorus Compounds; Phorbol 12,13-Dibutyrate; Sarcoma, Kaposi; Thymidine; Tumor Cells, Cultured; Virus Latency | 1997 |
The antiviral agent cidofovir [(S)-1-(3-hydroxy-2-phosphonyl-methoxypropyl)cytosine] has pronounced activity against nasopharyngeal carcinoma grown in nude mice.
Topics: Adolescent; Animals; Antiviral Agents; Apoptosis; Carcinoma; Cidofovir; Cytosine; Drug Screening Assays, Antitumor; Female; Ganciclovir; Genes, p53; Herpesviridae Infections; Herpesvirus 4, Human; Humans; Injections, Intralesional; Mice; Mice, Nude; Nasopharyngeal Neoplasms; Neoplasm Transplantation; Organophosphonates; Organophosphorus Compounds; Tumor Virus Infections | 1998 |
Clinical failure of CMV retinitis with intravitreal cidofovir is associated with antiviral resistance.
Topics: Adult; AIDS-Related Opportunistic Infections; Antiviral Agents; Cidofovir; Cytomegalovirus; Cytomegalovirus Retinitis; Cytosine; DNA, Viral; Drug Resistance, Microbial; Ganciclovir; Humans; Injections; Male; Middle Aged; Organophosphonates; Organophosphorus Compounds; Polymerase Chain Reaction; Treatment Failure; Vitreous Body | 1998 |
Interpreting human cytomegalovirus antiviral drug susceptibility testing: the role of mixed virus populations.
Topics: Antiviral Agents; Cidofovir; Cytomegalovirus; Cytosine; Drug Resistance, Microbial; Foscarnet; Ganciclovir; Humans; Microbial Sensitivity Tests; Organophosphonates; Organophosphorus Compounds | 1998 |
New issues in the management of cytomegalovirus retinitis in AIDS patients.
Topics: AIDS-Related Opportunistic Infections; Antiviral Agents; Cidofovir; Cytomegalovirus Retinitis; Cytosine; Drug Implants; Foscarnet; Ganciclovir; Humans; Organophosphonates; Organophosphorus Compounds | 1998 |
Lack of efficacy of cidofovir in treating AIDS-related cytomegalovirus retinitis after long-term treatment with ganciclovir.
Topics: Adult; AIDS-Related Opportunistic Infections; Anti-HIV Agents; Cidofovir; Cytomegalovirus Retinitis; Cytosine; Foscarnet; Ganciclovir; Humans; Male; Organophosphonates; Organophosphorus Compounds; Recurrence | 1998 |
Guidelines for the treatment of cytomegalovirus diseases in patients with AIDS in the era of potent antiretroviral therapy: recommendations of an international panel. International AIDS Society-USA.
Topics: AIDS-Related Opportunistic Infections; Anti-HIV Agents; Antiviral Agents; Cidofovir; Cytomegalovirus Infections; Cytosine; Foscarnet; Ganciclovir; Humans; Lung Diseases; Nervous System Diseases; Organophosphonates; Organophosphorus Compounds; Retinitis | 1998 |
Characterization of drug resistance-associated mutations in the human cytomegalovirus DNA polymerase gene by using recombinant mutant viruses generated from overlapping DNA fragments.
Topics: Antiviral Agents; Cidofovir; Cytomegalovirus; Cytosine; DNA Replication; DNA-Directed DNA Polymerase; DNA, Viral; Drug Resistance, Microbial; Foscarnet; Ganciclovir; Genes, Viral; Humans; Mutation; Organophosphonates; Organophosphorus Compounds; Recombination, Genetic; Virus Replication | 1998 |
A point mutation in the human cytomegalovirus DNA polymerase gene selected in vitro by cidofovir confers a slow replication phenotype in cell culture.
Topics: Amino Acid Sequence; Antiviral Agents; Cells, Cultured; Cidofovir; Cytomegalovirus; Cytosine; DNA Replication; DNA-Directed DNA Polymerase; DNA, Viral; Drug Resistance, Microbial; Enzyme Repression; Exonucleases; Ganciclovir; Molecular Sequence Data; Organophosphonates; Organophosphorus Compounds; Phenotype; Phosphodiesterase I; Phosphoric Diester Hydrolases; Point Mutation; Sequence Homology, Amino Acid; Viral Proteins; Virus Replication | 1998 |
[Comparison of the in vitro sensitivity to cidofovir and ganciclovir of clinical cytomegalovirus isolates. Coordinated Action Group 11].
Topics: Antiviral Agents; Cidofovir; Cytomegalovirus; Cytosine; Drug Resistance, Microbial; Drug Resistance, Multiple; Enzyme Inhibitors; Ganciclovir; Humans; Microbial Sensitivity Tests; Nucleic Acid Synthesis Inhibitors; Organophosphonates; Organophosphorus Compounds; Phosphotransferases (Alcohol Group Acceptor); Viral Proteins | 1998 |
Cytomegalovirus retinitis and viral resistance: 3. Culture results. CMV Retinitis and Viral Resistance Study Group.
Topics: Adult; AIDS-Related Opportunistic Infections; Antiviral Agents; Baltimore; Blood; Cidofovir; Cytomegalovirus; Cytomegalovirus Retinitis; Cytosine; Drug Resistance, Microbial; Female; Follow-Up Studies; Foscarnet; Ganciclovir; Humans; Male; Organophosphonates; Organophosphorus Compounds; Prognosis; Prospective Studies; Survival Rate; Urine; Viremia | 1998 |
In vitro antiviral susceptibilities of isolates from cytomegalovirus retinitis patients receiving first- or second-line cidofovir therapy: relationship to clinical outcome.
Topics: Antiviral Agents; Cidofovir; Cytomegalovirus; Cytomegalovirus Retinitis; Cytosine; Drug Resistance, Microbial; Foscarnet; Ganciclovir; Genotype; Humans; Microbial Sensitivity Tests; Organophosphonates; Organophosphorus Compounds; Recurrence | 1998 |
Discontinuing anticytomegalovirus therapy in patients with immune reconstitution after combination antiretroviral therapy.
Topics: Adult; AIDS-Related Opportunistic Infections; Antiviral Agents; CD4 Lymphocyte Count; CD4-Positive T-Lymphocytes; Cidofovir; Cytomegalovirus Retinitis; Cytosine; Drug Implants; Drug Therapy, Combination; Female; Ganciclovir; HIV-1; Humans; Male; Middle Aged; Organophosphonates; Organophosphorus Compounds; Viral Load | 1998 |
A high throughput colorimetric cell proliferation assay for the identification of human cytomegalovirus inhibitors.
Topics: Antiviral Agents; Cidofovir; Colorimetry; Cytomegalovirus; Cytopathogenic Effect, Viral; Cytosine; Fibroblasts; Ganciclovir; Humans; Microbial Sensitivity Tests; Organophosphonates; Organophosphorus Compounds; Tetrazolium Salts; Virus Replication | 1999 |
Inhibition of the in vitro growth of Plasmodium falciparum by acyclic nucleoside phosphonates.
Topics: Adenine; Animals; Antimalarials; Cidofovir; Cytosine; Erythrocytes; Ganciclovir; Humans; Nucleic Acid Synthesis Inhibitors; Organophosphonates; Organophosphorus Compounds; Plasmodium falciparum; Structure-Activity Relationship | 1999 |
Quantitative changes in cytomegalovirus DNAemia and genetic analysis of the UL97 and UL54 genes in AIDS patients receiving cidofovir following ganciclovir therapy.
Topics: Acquired Immunodeficiency Syndrome; Antiviral Agents; Cidofovir; Cytomegalovirus; Cytomegalovirus Infections; Cytosine; DNA-Directed DNA Polymerase; DNA, Viral; Ganciclovir; Genotype; Humans; Mutation; Organophosphonates; Organophosphorus Compounds; Phosphotransferases (Alcohol Group Acceptor); Prospective Studies; Retinitis; Viral Load; Viral Proteins | 1999 |
The antisense oligonucleotide ISIS 2922 prevents cytomegalovirus-induced upregulation of IL-8 and ICAM-1 in cultured human fibroblasts.
Topics: Antiviral Agents; Cells, Cultured; Chemotaxis, Leukocyte; Cidofovir; Cytomegalovirus Infections; Cytosine; Fibroblasts; Foscarnet; Ganciclovir; Humans; Immunohistochemistry; Intercellular Adhesion Molecule-1; Interleukin-8; Neutrophils; Oligonucleotides, Antisense; Organophosphonates; Organophosphorus Compounds; Reverse Transcriptase Polymerase Chain Reaction; Thionucleotides; Up-Regulation | 2000 |
Acute murine cytomegalovirus infection: a model for determining antiviral activity against CMV induced hepatitis.
Topics: Alanine Transaminase; Animals; Antiviral Agents; Aspartate Aminotransferases; Body Weight; Cidofovir; Cytomegalovirus Infections; Cytosine; Disease Models, Animal; Female; Ganciclovir; Hepatitis, Viral, Animal; Herpesviridae Infections; Liver; Mice; Mice, Inbred BALB C; Muromegalovirus; Organophosphonates; Organophosphorus Compounds; Virus Replication | 1999 |
Susceptibility of human herpesvirus 6 to antiviral compounds by flow cytometry analysis.
Topics: Antibodies, Monoclonal; Antigens, Surface; Antigens, Viral; Antiviral Agents; Cidofovir; Cytosine; Dose-Response Relationship, Drug; Flow Cytometry; Foscarnet; Ganciclovir; Herpesviridae Infections; Herpesvirus 6, Human; Humans; In Vitro Techniques; Leukocytes, Mononuclear; Organophosphonates; Organophosphorus Compounds; Reproducibility of Results | 2000 |
Cidofovir: new preparation. Of help in CMV retinitis.
Topics: Antiviral Agents; Clinical Trials as Topic; Cytomegalovirus Retinitis; Cytosine; Foscarnet; Ganciclovir; Humans; Treatment Outcome | 1998 |
[Stopping secondary prevention in AIDS patients with inactive CMV retinitis treated with HAART (highly active antiretroviral therapy)].
Topics: AIDS-Related Opportunistic Infections; Antiretroviral Therapy, Highly Active; Antiviral Agents; Cidofovir; Cytomegalovirus Retinitis; Cytosine; Follow-Up Studies; Foscarnet; Ganciclovir; Humans; Organophosphonates; Organophosphorus Compounds | 2000 |
A deletion mutation in region V of the cytomegalovirus DNA polymerase sequence confers multidrug resistance.
Topics: Acquired Immunodeficiency Syndrome; Antiviral Agents; Cidofovir; Cytomegalovirus; Cytomegalovirus Retinitis; Cytosine; DNA-Directed DNA Polymerase; Drug Resistance, Microbial; Drug Resistance, Multiple; Foscarnet; Ganciclovir; Gene Deletion; Humans; Mutation; Organophosphonates; Organophosphorus Compounds; Phosphotransferases; Transfection | 2000 |
Fatal cytomegalovirus pneumonia after preemptive antiviral therapy in a renal transplant recipient.
Topics: Antigens, Viral; Antiviral Agents; Cidofovir; Cytomegalovirus; Cytomegalovirus Infections; Cytosine; Fatal Outcome; Female; Foscarnet; Ganciclovir; Humans; Kidney Transplantation; Middle Aged; Organophosphonates; Organophosphorus Compounds; Pneumonia, Viral; Polymerase Chain Reaction; Postoperative Complications | 2000 |
Isolation and analysis of an aciclovir-resistant murine cytomegalovirus mutant.
Topics: Acyclovir; Amino Acid Substitution; Animals; Antiviral Agents; Cells, Cultured; Cidofovir; Codon; Cytosine; DNA-Directed DNA Polymerase; Drug Resistance, Microbial; Ganciclovir; Inhibitory Concentration 50; Mice; Muromegalovirus; Mutation; Organophosphonates; Organophosphorus Compounds; Polymerase Chain Reaction; Polymorphism, Restriction Fragment Length; Virus Replication | 2001 |
Virological, clinical, and ophthalmologic features of cytomegalovirus retinitis after hematopoietic stem cell transplantation.
Topics: Adult; Antiviral Agents; Chronic Disease; Cidofovir; Cytomegalovirus; Cytomegalovirus Retinitis; Cytosine; Female; Foscarnet; Ganciclovir; Graft vs Host Disease; Hematopoietic Stem Cell Transplantation; Humans; Incidence; Male; Middle Aged; Organophosphonates; Organophosphorus Compounds; Postoperative Complications; Risk Factors; Treatment Outcome; Virus Activation | 2001 |
In vitro effects of antiviral agents on human keratocytes.
Topics: Antiviral Agents; Cell Survival; Cells, Cultured; Cidofovir; Colorimetry; Corneal Stroma; Cytosine; Dose-Response Relationship, Drug; Fibroblasts; Ganciclovir; Humans; Idoxuridine; Microscopy, Phase-Contrast; Organophosphonates; Organophosphorus Compounds; Trifluridine | 2001 |
Failure of cidofovir to reduce CMV-antigenemia in a child transplanted from a matched unrelated donor.
Topics: Adenoviridae; Antiviral Agents; Bone Marrow Transplantation; Child; Cidofovir; Cytomegalovirus Infections; Cytosine; Drug Evaluation; Foscarnet; Ganciclovir; Humans; Immunocompromised Host; Male; Organophosphonates; Organophosphorus Compounds; Treatment Outcome | 2001 |
Ganciclovir and cidofovir treatment of cytomegalovirus-induced myocarditis in mice.
Topics: Animals; Antiviral Agents; Cidofovir; Cytosine; Disease Models, Animal; Ganciclovir; Herpesviridae Infections; Male; Mice; Mice, Inbred BALB C; Microbial Sensitivity Tests; Muromegalovirus; Myocarditis; Organophosphonates; Organophosphorus Compounds | 2001 |
CMV retinitis: a clinical management update.
Topics: AIDS-Related Opportunistic Infections; Algorithms; Antiviral Agents; Cidofovir; Clinical Protocols; Clinical Trials as Topic; Cytomegalovirus; Cytomegalovirus Retinitis; Cytosine; Drug Implants; Drug Resistance, Microbial; Drug Therapy, Combination; Foscarnet; Ganciclovir; Humans; Injections; Organophosphonates; Organophosphorus Compounds; Patient Participation; Vitreous Body | 1996 |
Second National Retrovirus conference: a further report.
Topics: Acetamides; Acetophenones; Acquired Immunodeficiency Syndrome; Adult; Antiviral Agents; Cause of Death; Cidofovir; Cytomegalovirus Retinitis; Cytosine; Female; Ganciclovir; Humans; Male; Organophosphonates; Organophosphorus Compounds; Paclitaxel; Reverse Transcriptase Inhibitors; Sarcoma, Kaposi; Tuberculosis | 1995 |
Advances in the treatment of CMV.
Topics: AIDS-Related Opportunistic Infections; Antiviral Agents; Cidofovir; Clinical Trials, Phase I as Topic; Clinical Trials, Phase III as Topic; Cytomegalovirus Retinitis; Cytosine; Drug Implants; Drug Therapy, Combination; Eye; Foscarnet; Ganciclovir; Humans; Organophosphonates; Organophosphorus Compounds; Quality of Life | 1995 |
Fomivirsen.
Topics: AIDS-Related Opportunistic Infections; Antiviral Agents; Cidofovir; Clinical Trials as Topic; Cytomegalovirus Retinitis; Cytosine; Disease Progression; Foscarnet; Ganciclovir; Health Services Accessibility; Humans; Organophosphonates; Organophosphorus Compounds; Thionucleotides | 1998 |
Strategies for management of cytomegalovirus (CMV) infection after allogeneic bone marrow transplantation: the "doubling of baseline CMV pp65 antigenemia" and the "cidofovir as rescue treatment approaches.
Topics: Antigens, Viral; Antiviral Agents; Bone Marrow Transplantation; Child; Cidofovir; Cytomegalovirus; Cytomegalovirus Infections; Cytosine; Drug Resistance, Microbial; Drug Therapy, Combination; Foscarnet; Ganciclovir; Humans; Organophosphonates; Organophosphorus Compounds; Phosphoproteins; Recurrence; Salvage Therapy; Time Factors; Transplantation, Homologous; Viral Matrix Proteins; Viremia | 2001 |
Quantification of cytomegalovirus (CMV) viral load by the hybrid capture assay allows for early detection of CMV disease in lung transplant recipients.
Topics: Adult; Antiviral Agents; Cell Culture Techniques; Cidofovir; Cytomegalovirus; Cytomegalovirus Infections; Cytosine; DNA, Viral; Female; Ganciclovir; Humans; Illinois; Immunization, Passive; Lung Transplantation; Male; Middle Aged; Nucleic Acid Hybridization; Organophosphonates; Organophosphorus Compounds; Predictive Value of Tests; Prospective Studies; Reagent Kits, Diagnostic; Sensitivity and Specificity; Survival Analysis; Syndrome; Viral Load | 2001 |
Cytomegalovirus ventriculoencephalitis in a bone marrow transplant recipient receiving antiviral maintenance: clinical and molecular evidence of drug resistance.
Topics: Antiviral Agents; Bone Marrow Transplantation; Cerebral Ventricles; Child; Cidofovir; Cytomegalovirus Retinitis; Cytosine; Drug Combinations; Drug Resistance, Viral; Encephalitis, Viral; Female; Foscarnet; Ganciclovir; Humans; Immunocompromised Host; Organophosphonates; Organophosphorus Compounds | 2001 |
Predictive efficacy of SCID-hu mouse models for treatment of human cytomegalovirus infections.
Topics: Animals; Antiviral Agents; Cidofovir; Cytomegalovirus; Cytomegalovirus Infections; Cytosine; Disease Models, Animal; Ganciclovir; Humans; Mice; Mice, SCID; Organophosphonates; Organophosphorus Compounds; Virus Replication | 2001 |
A case of flare syndrome.
Topics: Acute Disease; Adult; AIDS-Related Opportunistic Infections; Antiretroviral Therapy, Highly Active; Antiviral Agents; CD4 Lymphocyte Count; Cidofovir; Cytomegalovirus Retinitis; Cytosine; Drug Therapy, Combination; Ganciclovir; HIV Infections; Humans; Indinavir; Lamivudine; Male; Organophosphonates; Organophosphorus Compounds; Zidovudine | 2001 |
Antiviral therapy for cytomegalovirus infections in pediatric patients.
Topics: Acquired Immunodeficiency Syndrome; Administration, Oral; Adolescent; Adult; AIDS-Related Opportunistic Infections; Antiviral Agents; Child; Child, Preschool; Cidofovir; Cytomegalovirus Infections; Cytosine; Foscarnet; Ganciclovir; Humans; Immunocompromised Host; Infant; Injections, Intravenous; Organophosphonates; Organophosphorus Compounds; Time Factors | 2002 |
Prevention of cytomegalovirus disease in hematopoietic stem cell transplantation.
Topics: Acyclovir; Antiviral Agents; Chemoprevention; Cidofovir; Cytomegalovirus; Cytomegalovirus Infections; Cytosine; Ganciclovir; Hematopoietic Stem Cell Transplantation; Humans; Organophosphonates; Organophosphorus Compounds; Postoperative Complications; Risk Factors; Transplantation, Autologous; Transplantation, Homologous; Valacyclovir; Valganciclovir; Valine | 2002 |
Successful treatment of varicella zoster virus retinitis with aggressive intravitreal and systemic antiviral therapy.
Topics: Acquired Immunodeficiency Syndrome; Adult; Antiviral Agents; Cidofovir; Cytosine; Drug Therapy, Combination; Female; Foscarnet; Ganciclovir; Herpes Zoster Ophthalmicus; Humans; Injections, Intravenous; Male; Organophosphonates; Organophosphorus Compounds; Retinitis; Vitreous Body | 2002 |
Determination of antiviral efficacy against lymphotropic herpesviruses utilizing flow cytometry.
Topics: Acyclovir; Antibodies, Viral; Antiviral Agents; Cells, Cultured; Cidofovir; Cytosine; Flow Cytometry; Foscarnet; Ganciclovir; Herpesvirus 4, Human; Herpesvirus 6, Human; Herpesvirus 8, Human; Humans; Organophosphonates; Organophosphorus Compounds | 2003 |
Synergy of bovine lactoferrin with the anti-cytomegalovirus drug cidofovir in vitro.
Topics: Acyclovir; Animals; Antiviral Agents; Cattle; Cells, Cultured; Cidofovir; Cytomegalovirus; Cytosine; Drug Synergism; Foscarnet; Ganciclovir; Inhibitory Concentration 50; Lactoferrin; Organophosphonates; Organophosphorus Compounds | 2003 |
Evaluation of susceptibility of human herpesvirus 8 to antiviral drugs by quantitative real-time PCR.
Topics: Antiviral Agents; Cidofovir; Cytosine; Ganciclovir; Herpesvirus 8, Human; Humans; Microbial Sensitivity Tests; Organophosphonates; Organophosphorus Compounds; Polymerase Chain Reaction; Regression Analysis | 2003 |
Human cytomegalovirus double resistance in a donor-positive/recipient-negative lung transplant patient with an impaired CD4-mediated specific immune response.
Topics: Antigens, Viral; Antiviral Agents; CD4 Lymphocyte Count; CD4-Positive T-Lymphocytes; Cidofovir; Cytokines; Cytomegalovirus; Cytomegalovirus Infections; Cytosine; DNA, Viral; Drug Resistance, Viral; Ganciclovir; Humans; Immunity, Cellular; Lung; Lung Transplantation; Male; Middle Aged; Organophosphonates; Organophosphorus Compounds | 2004 |
Comparison of sequential cytomegalovirus isolates in a patient with lymphoma and failing antiviral therapy.
Topics: Aged; Antiviral Agents; Cidofovir; Cytomegalovirus; Cytomegalovirus Infections; Cytosine; DNA, Viral; Drug Resistance, Viral; Evolution, Molecular; Female; Foscarnet; Ganciclovir; Humans; Lymphoma, T-Cell; Molecular Epidemiology; Mutation, Missense; Organophosphonates; Organophosphorus Compounds; Polymorphism, Restriction Fragment Length; Sequence Analysis, DNA | 2004 |
In vitro efficacy of ganciclovir, cidofovir, penciclovir, foscarnet, idoxuridine, and acyclovir against feline herpesvirus type-1.
Topics: Acyclovir; Animals; Antiviral Agents; Cats; Cells, Cultured; Cidofovir; Cytosine; Dose-Response Relationship, Drug; Foscarnet; Ganciclovir; Guanine; Idoxuridine; In Vitro Techniques; Inhibitory Concentration 50; Organophosphonates; Organophosphorus Compounds; Varicellovirus; Virus Replication | 2004 |
Susceptibility of porcine cytomegalovirus to antiviral drugs.
Topics: Animals; Antiviral Agents; Cell Survival; Cidofovir; Cytomegalovirus; Cytosine; DNA, Viral; Fluorescent Antibody Technique, Indirect; Foscarnet; Ganciclovir; Organophosphonates; Organophosphorus Compounds; Reverse Transcriptase Polymerase Chain Reaction; Swine; Virus Replication | 2004 |
Evaluation of antiviral activity against human herpesvirus 8 (HHV-8) and Epstein-Barr virus (EBV) by a quantitative real-time PCR assay.
Topics: Acyclovir; Antiviral Agents; Cell Line; Cidofovir; Cytosine; Ganciclovir; Herpesvirus 4, Human; Herpesvirus 8, Human; Humans; Microbial Sensitivity Tests; Organophosphonates; Organophosphorus Compounds; Polymerase Chain Reaction | 2004 |
Efficacy of ganciclovir and cidofovir against human cytomegalovirus replication in SCID mice implanted with human retinal tissue.
Topics: Animals; Antiviral Agents; Cidofovir; Cytomegalovirus; Cytomegalovirus Retinitis; Cytosine; Disease Models, Animal; Ganciclovir; Humans; Mice; Mice, SCID; Organophosphonates; Organophosphorus Compounds; Transplantation, Heterologous; Virus Replication | 2004 |
Successful treatment of human herpesvirus 6 encephalomyelitis in immunocompetent patient.
Topics: Adult; Antiviral Agents; Cidofovir; Cytosine; Drug Therapy, Combination; Encephalomyelitis; Female; Ganciclovir; Herpesvirus 6, Human; Humans; Immunocompetence; Organophosphonates; Organophosphorus Compounds; Roseolovirus Infections | 2004 |
Novel chemical class of pUL97 protein kinase-specific inhibitors with strong anticytomegaloviral activity.
Topics: Antiviral Agents; Blotting, Western; Cell Line; Cells, Cultured; Cidofovir; Cytomegalovirus; Cytosine; Drug Resistance, Viral; Enzyme Inhibitors; Ganciclovir; Humans; Organophosphonates; Phosphotransferases (Alcohol Group Acceptor); Plasmids; Quinazolines; Viral Plaque Assay; Virus Replication | 2004 |
Characterization of a novel intraocular drug-delivery system using crystalline lipid antiviral prodrugs of ganciclovir and cyclic cidofovir.
Topics: Animals; Antiviral Agents; Area Under Curve; Biological Availability; Chromatography, High Pressure Liquid; Cytosine; Drug Delivery Systems; Eye Infections, Viral; Ganciclovir; Herpes Simplex; Herpesvirus 1, Human; Liposomes; Microfluidics; Organophosphonates; Prodrugs; Rabbits; Retina; Retinitis; Vitreous Body | 2004 |
Murine cytomegalovirus resistant to antivirals has genetic correlates with human cytomegalovirus.
Topics: Acyclovir; Adenine; Animals; Antiviral Agents; Cidofovir; Cytomegalovirus; Cytosine; DNA-Directed DNA Polymerase; Drug Resistance, Viral; Ganciclovir; Guanine; Humans; Mice; Models, Molecular; Molecular Sequence Data; Muromegalovirus; Mutation; Organophosphonates; Protein Kinases; Sequence Alignment; Valacyclovir; Valine; Virus Replication | 2005 |
Cidofovir for cytomegalovirus reactivation in pediatric patients after hematopoietic stem cell transplantation.
Topics: Adolescent; Antigens, Viral; Antiviral Agents; Child; Cidofovir; Creatinine; Cytomegalovirus Infections; Cytosine; Female; Foscarnet; Ganciclovir; Hematopoietic Stem Cell Transplantation; Humans; Male; Organophosphonates; Premedication; Virus Activation | 2005 |
New reporter cell line to evaluate the sequential emergence of multiple human cytomegalovirus mutations during in vitro drug exposure.
Topics: Amino Acid Sequence; Antiviral Agents; Cell Line; Cidofovir; Cytomegalovirus; Cytosine; DNA Replication; DNA, Viral; Drug Resistance, Viral; Ganciclovir; Humans; Molecular Sequence Data; Mutation; Organophosphonates | 2005 |
Maribavir sensitivity of cytomegalovirus isolates resistant to ganciclovir, cidofovir or foscarnet.
Topics: Antiviral Agents; Benzimidazoles; Cidofovir; Cytomegalovirus; Cytosine; DNA-Directed DNA Polymerase; Drug Resistance, Viral; Foscarnet; Ganciclovir; Humans; Mutation; Organophosphonates; Phosphotransferases (Alcohol Group Acceptor); Ribonucleosides; Viral Proteins | 2006 |
Multidrug resistance conferred by novel DNA polymerase mutations in human cytomegalovirus isolates.
Topics: Antiviral Agents; Cidofovir; Cytomegalovirus; Cytomegalovirus Infections; Cytosine; DNA Replication; DNA-Directed DNA Polymerase; Drug Resistance, Multiple; Drug Resistance, Viral; Foscarnet; Ganciclovir; Genotype; Humans; Immunocompromised Host; Mutation; Organophosphonates; Phenotype; Viral Proteins; Virus Replication | 2007 |
In vitro susceptibility of six isolates of equine herpesvirus 1 to acyclovir, ganciclovir, cidofovir, adefovir, PMEDAP and foscarnet.
Topics: Acyclovir; Adenine; Animals; Antiviral Agents; Cell Survival; Cells, Cultured; Cidofovir; Cytosine; Dose-Response Relationship, Drug; Drug Resistance, Viral; Epithelial Cells; Foscarnet; Ganciclovir; Herpesvirus 1, Equid; Horses; Lung; Organophosphonates | 2007 |
Leflunomide failure to control recurrent cytomegalovirus infection in the setting of renal failure after allogeneic stem cell transplantation.
Topics: Antiviral Agents; Cidofovir; Cytomegalovirus; Cytomegalovirus Infections; Cytosine; Drug Therapy, Combination; Encephalitis, Viral; Fatal Outcome; Ganciclovir; Hodgkin Disease; Humans; Isoxazoles; Leflunomide; Male; Middle Aged; Organophosphonates; Peripheral Blood Stem Cell Transplantation; Postoperative Complications; Renal Insufficiency; Secondary Prevention; Treatment Failure; Virus Activation | 2007 |
A model of human cytomegalovirus infection in severe combined immunodeficient mice.
Topics: Animals; Antiviral Agents; Cell Culture Techniques; Cell Line; Cidofovir; Cytomegalovirus; Cytomegalovirus Infections; Cytosine; Disease Models, Animal; Ganciclovir; Gelatin Sponge, Absorbable; Humans; Male; Mice; Mice, SCID; Organophosphonates; Viral Plaque Assay | 2007 |
Accelerated evolution of maribavir resistance in a cytomegalovirus exonuclease domain II mutant.
Topics: Amino Acid Sequence; Amino Acid Substitution; Antiviral Agents; Benzimidazoles; Cells, Cultured; Cidofovir; Cytomegalovirus; Cytomegalovirus Infections; Cytosine; DNA-Directed DNA Polymerase; Drug Resistance, Viral; Foscarnet; Ganciclovir; Humans; Models, Molecular; Molecular Sequence Data; Mutant Proteins; Organophosphonates; Phosphotransferases (Alcohol Group Acceptor); Protein Structure, Tertiary; Ribonucleosides; Sequence Alignment; Viral Proteins | 2008 |
Contrasting drug resistance phenotypes resulting from cytomegalovirus DNA polymerase mutations at the same exonuclease locus.
Topics: Antiviral Agents; Cidofovir; Cytomegalovirus; Cytomegalovirus Infections; Cytosine; DNA-Directed DNA Polymerase; Drug Resistance, Viral; Exodeoxyribonucleases; Foscarnet; Ganciclovir; Humans; Mutation; Organophosphonates; Phenotype; Protein Structure, Tertiary; Viral Proteins | 2008 |
Case report: persistent cytomegalovirus (CMV) infection after haploidentical hematopoietic stem cell transplantation using in vivo alemtuzumab: emergence of resistant CMV due to mutations in the UL97 and UL54 genes.
Topics: Alemtuzumab; Anemia, Refractory, with Excess of Blasts; Antibodies, Monoclonal; Antibodies, Monoclonal, Humanized; Antibodies, Neoplasm; Antiviral Agents; Base Sequence; Cidofovir; Cytomegalovirus; Cytomegalovirus Retinitis; Cytosine; DNA-Directed DNA Polymerase; Drug Resistance, Viral; Foscarnet; Ganciclovir; Hematopoietic Stem Cell Transplantation; Humans; Immunosuppressive Agents; Male; Microbial Sensitivity Tests; Middle Aged; Molecular Sequence Data; Organophosphonates; Phosphotransferases (Alcohol Group Acceptor); Point Mutation; Viral Proteins; Virus Activation | 2008 |
Intravenous immunoglobulin as rescue therapy for BK virus nephropathy.
Topics: Antiviral Agents; BK Virus; Child, Preschool; Cidofovir; Creatinine; Cytosine; Ganciclovir; Humans; Immunoglobulins, Intravenous; Immunologic Factors; Kidney; Kidney Transplantation; Male; Organophosphonates; Polyomavirus Infections; Tumor Virus Infections | 2009 |
Development of herpes simplex virus stomatitis during receipt of cidofovir therapy.
Topics: Acyclovir; Antiviral Agents; Chemoprevention; Child; Child, Preschool; Cidofovir; Cytomegalovirus Infections; Cytosine; Ganciclovir; Humans; Male; Organophosphonates; Simplexvirus; Stem Cell Transplantation; Stomatitis; Treatment Outcome | 2009 |
Longitudinal analysis of human herpesvirus-8 DNA and antibodies in an Italian allogeneic stem cell transplant recipient.
Topics: Antibodies, Viral; Cidofovir; Cytosine; DNA, Viral; Encephalitis; Fatal Outcome; Foscarnet; Ganciclovir; Herpesviridae Infections; Herpesvirus 8, Human; Humans; Italy; Leukemia, Lymphocytic, Chronic, B-Cell; Male; Middle Aged; Organophosphonates; Stem Cell Transplantation; Transplantation, Homologous | 2011 |
Cyclopropavir susceptibility of cytomegalovirus DNA polymerase mutants selected after antiviral drug exposure.
Topics: Alkaline Phosphatase; Antiviral Agents; Cidofovir; Cyclopropanes; Cytomegalovirus; Cytomegalovirus Infections; Cytosine; DNA-Directed DNA Polymerase; Drug Resistance, Viral; Exonucleases; Foscarnet; Ganciclovir; Genes, Reporter; Genotype; Guanine; Humans; Inhibitory Concentration 50; Mutation; Organophosphonates; Phenotype; Viral Proteins; Virus Replication | 2012 |
Ganciclovir-resistant cytomegalovirus (CMV) retinitis in a patient with wild-type CMV in her plasma.
Topics: Adult; Antiviral Agents; Cidofovir; Cytomegalovirus; Cytomegalovirus Retinitis; Cytosine; DNA, Viral; Drug Resistance, Viral; Eye; Female; Foscarnet; Ganciclovir; Humans; Organophosphonates; Plasma; Sequence Analysis, DNA | 2012 |
Case report: Multidrug-resistant cytomegalovirus in a modified multivisceral transplant recipient.
Topics: Adult; Antiviral Agents; Cidofovir; Cytomegalovirus; Cytomegalovirus Infections; Cytosine; Drug Resistance, Multiple, Viral; Female; Foscarnet; Ganciclovir; Humans; Immunosuppressive Agents; Intestine, Small; Isoxazoles; Kidney Transplantation; Leflunomide; Organophosphonates; Pancreas Transplantation; Recurrence; Stomach; Treatment Outcome | 2012 |
Selection and recombinant phenotyping of a novel CMX001 and cidofovir resistance mutation in human cytomegalovirus.
Topics: Amino Acid Sequence; Antiviral Agents; Base Sequence; Cells, Cultured; Chromosomes, Artificial, Bacterial; Cidofovir; Cytomegalovirus; Cytomegalovirus Infections; Cytosine; DNA-Directed DNA Polymerase; Drug Resistance, Viral; Foscarnet; Ganciclovir; Humans; Mutation; Organophosphonates; Phenotype; Sequence Analysis, DNA | 2013 |
Generation and characterization of a GCV resistant HCMV UL97-mutation and a drug sensitive UL54-mutation.
Topics: Antiviral Agents; Chromosomes, Artificial, Bacterial; Cidofovir; Cytomegalovirus; Cytomegalovirus Infections; Cytosine; DNA-Directed DNA Polymerase; Drug Resistance, Multiple, Viral; Foscarnet; Ganciclovir; Genes, Viral; Humans; Mutagenesis; Mutation, Missense; Organophosphonates; Phenotype; Phosphotransferases (Alcohol Group Acceptor); Point Mutation; Viral Proteins | 2013 |
Cytomegalovirus mutants resistant to ganciclovir and cidofovir differ in susceptibilities to synguanol and its 6-ether and 6-thioether derivatives.
Topics: Antiviral Agents; Cidofovir; Cyclopropanes; Cytomegalovirus; Cytosine; Drug Resistance, Multiple, Viral; Foscarnet; Ganciclovir; Genotype; Guanine; Mutation; Organophosphonates | 2014 |
UL54 foscarnet mutation in an hematopoietic stem cell transplant recipient with cytomegalovirus disease.
Topics: Antiviral Agents; Cidofovir; Cytomegalovirus; Cytomegalovirus Infections; Cytosine; DNA-Directed DNA Polymerase; Drug Resistance, Viral; Foscarnet; Ganciclovir; Hematopoietic Stem Cell Transplantation; Humans; Male; Middle Aged; Mutation; Organophosphonates; Viral Proteins | 2014 |
Improved detection of emerging drug-resistant mutant cytomegalovirus subpopulations by deep sequencing.
Topics: Antiviral Agents; Cidofovir; Cytomegalovirus; Cytomegalovirus Infections; Cytosine; DNA-Directed DNA Polymerase; Drug Resistance, Viral; Foscarnet; Ganciclovir; High-Throughput Nucleotide Sequencing; Humans; Immunocompromised Host; Leukemia, Lymphocytic, Chronic, B-Cell; Male; Middle Aged; Mutation; Organophosphonates; Pneumonia, Viral; Time Factors; Viral Proteins; Virus Replication | 2014 |
Ganciclovir inhibits human adenovirus replication and pathogenicity in permissive immunosuppressed Syrian hamsters.
Topics: Adenoviridae Infections; Adenoviruses, Human; Animals; Antiviral Agents; Body Weight; Cell Line, Tumor; Cytosine; DNA-Directed DNA Polymerase; Female; Ganciclovir; Gene Expression; Humans; Immunocompromised Host; Male; Mesocricetus; Organophosphonates; Survival Analysis; Transaminases; Viral Load; Viral Proteins; Virus Replication | 2014 |
Papiine herpesvirus 2 as a predictive model for drug sensitivity of Macacine herpesvirus 1 (monkey B virus).
Topics: Animals; Antiviral Agents; Chlorocebus aethiops; Cidofovir; Cytosine; Disease Models, Animal; Ganciclovir; Herpesviridae Infections; Herpesvirus 1, Cercopithecine; Macaca mulatta; Mice; Organophosphonates; Simplexvirus; Trifluridine; Vero Cells; Viral Plaque Assay | 2014 |
Identification of newly detected, drug-related HCMV UL97- and UL54-mutations using a modified plaque reduction assay.
Topics: Adult; Antiviral Agents; Cell Line; Child; Chromosomes, Artificial, Bacterial; Cidofovir; Cytomegalovirus; Cytomegalovirus Infections; Cytosine; DNA-Directed DNA Polymerase; Drug Resistance, Multiple, Viral; Female; Ganciclovir; Genotype; Humans; Infant; Male; Mutation; Organophosphonates; Phosphotransferases (Alcohol Group Acceptor); Viral Proteins | 2015 |
Contrasting effect of new HCMV pUL54 mutations on antiviral drug susceptibility: Benefits and limits of 3D analysis.
Topics: Antiviral Agents; Chromosomes, Artificial, Bacterial; Cytomegalovirus; Cytosine; DNA-Directed DNA Polymerase; DNA, Viral; Drug Resistance, Viral; Foscarnet; Ganciclovir; Humans; Models, Molecular; Mutagenesis; Organophosphonates; Phenotype; Point Mutation; Protein Domains; Viral Proteins | 2016 |
Novel Cytomegalovirus UL54 DNA Polymerase Gene Mutations Selected In Vitro That Confer Brincidofovir Resistance.
Topics: Antiviral Agents; Cidofovir; Cytomegalovirus; Cytomegalovirus Infections; Cytosine; DNA-Directed DNA Polymerase; Drug Resistance, Viral; Foscarnet; Ganciclovir; Gene Expression; Humans; Microbial Sensitivity Tests; Mutation; Organophosphonates; Protein Domains; Viral Proteins | 2016 |
Identification of resistance-associated HCMV UL97- and UL54-mutations and a UL97-polymporphism with impact on phenotypic drug-resistance.
Topics: Adolescent; Adult; Antiviral Agents; Child; Chromosomes, Artificial, Bacterial; Cidofovir; Cytomegalovirus; Cytomegalovirus Infections; Cytosine; DNA-Directed DNA Polymerase; DNA, Viral; Drug Resistance, Viral; Foscarnet; Ganciclovir; Genotype; Humans; Immunocompromised Host; Infant; Middle Aged; Mutation; Organophosphonates; Phenotype; Phosphotransferases (Alcohol Group Acceptor); Polymorphism, Genetic; Viral Proteins | 2016 |
Combination therapies using an intratympanic polymer gel delivery system in the guinea pig animal model: A safety study.
Topics: Animals; Antiviral Agents; Cidofovir; Cytosine; Dexamethasone; Drug Combinations; Drug Delivery Systems; Follow-Up Studies; Ganciclovir; Glucocorticoids; Guinea Pigs; Hearing Loss; Hydrogels; Injection, Intratympanic; Organophosphonates; Polyesters; Polyethylene Glycols; Polymers | 2016 |
Synthesis and Ativiral Activity of 5-(Benzylthio)-4-carbamyl-1,2,3-triazoles Against Human Cytomegalovirus (CMV) and Varicella-zoster Virus (VZV).
Topics: Acyclovir; Antiviral Agents; Bromodeoxyuridine; Cidofovir; Cytomegalovirus; Cytosine; Ganciclovir; Herpesvirus 1, Human; Herpesvirus 2, Human; Herpesvirus 3, Human; Organophosphonates; Thymidine Kinase; Triazoles | 2017 |
Epidemiology and Outcome of Ganciclovir-Resistant Cytomegalovirus Infection After Solid Organ Transplantation: A Single Transplant Center Experience in Thailand.
Topics: Adult; Antiviral Agents; Cidofovir; Cytomegalovirus; Cytomegalovirus Infections; Cytosine; Drug Resistance, Viral; Female; Foscarnet; Ganciclovir; Humans; Kidney Transplantation; Liver Transplantation; Male; Middle Aged; Mutation; Organ Transplantation; Organophosphonates; Postoperative Complications; Real-Time Polymerase Chain Reaction; Retrospective Studies; Thailand; Young Adult | 2017 |
HAdV-C6 Is a More Relevant Challenge Virus than HAdV-C5 for Testing Antiviral Drugs with the Immunosuppressed Syrian Hamster Model.
Topics: A549 Cells; Adenoviridae Infections; Adenovirus Infections, Human; Adenoviruses, Human; Animals; Antiviral Agents; Cell Line; Cidofovir; Cricetinae; Cytosine; Disease Models, Animal; Ganciclovir; Humans; Immunosuppression Therapy; Liver; Male; Organophosphonates; Valganciclovir; Viral Load; Virus Replication | 2017 |
Combination therapy with brincidofovir and valganciclovir against species C adenovirus infection in the immunosuppressed Syrian hamster model allows for substantial reduction of dose for both compounds.
Topics: Adenoviridae Infections; Adenoviruses, Human; Animals; Antiviral Agents; Cytosine; Disease Models, Animal; Drug Therapy, Combination; Ganciclovir; HEK293 Cells; Humans; Immunocompromised Host; Mesocricetus; Organophosphonates; Valganciclovir; Viral Load; Virus Replication | 2017 |
Ganciclovir Dosing Strategies and Development of Cytomegalovirus Resistance in a Kidney Transplant Recipient: A Case Report.
Topics: Aged; Antiviral Agents; Cidofovir; Cytomegalovirus; Cytomegalovirus Infections; Cytosine; Dose-Response Relationship, Drug; Drug Resistance, Viral; Foscarnet; Ganciclovir; Humans; Immunoglobulins; Immunoglobulins, Intravenous; Isoxazoles; Kidney; Kidney Transplantation; Leflunomide; Male; Organophosphonates; Postoperative Complications; Tissue Donors | 2017 |
In vitro evaluation of current and novel antivirals in combination against human cytomegalovirus.
Topics: Antiviral Agents; Benzimidazoles; Cell Line; Cidofovir; Cyclopropanes; Cytomegalovirus; Cytomegalovirus Infections; Cytosine; DNA-Directed DNA Polymerase; Drug Antagonism; Drug Combinations; Drug Resistance, Viral; Drug Synergism; Drug Therapy, Combination; Endodeoxyribonucleases; Fibroblasts; Foscarnet; Ganciclovir; Guanine; Humans; Nucleic Acid Synthesis Inhibitors; Organophosphonates; Ribonucleosides; Viral Proteins; Virus Replication | 2018 |
Artemisone demonstrates synergistic antiviral activity in combination with approved and experimental drugs active against human cytomegalovirus.
Topics: Acetates; Antiviral Agents; Artemisinins; Benzimidazoles; Cidofovir; Cytomegalovirus; Cytomegalovirus Infections; Cytosine; Drug Interactions; Drug Synergism; Drugs, Investigational; Female; Ganciclovir; Humans; Organ Culture Techniques; Organophosphonates; Placenta; Pregnancy; Quinazolines; Ribonucleosides | 2019 |
[Resistance to antiviral drugs in human viruses from the subfamily
Topics: Antiviral Agents; Betaherpesvirinae; Cytomegalovirus; Cytosine; DNA-Directed DNA Polymerase; Drug Resistance, Viral; Foscarnet; Ganciclovir; Humans | 2022 |