cytosine and decitabine

cytosine has been researched along with decitabine in 56 studies

Research

Studies (56)

Timeframe	Studies, this research(%)	All Research%
pre-1990	11 (19.64)	18.7374
1990's	8 (14.29)	18.2507
2000's	18 (32.14)	29.6817
2010's	18 (32.14)	24.3611
2020's	1 (1.79)	2.80

Authors

Authors	Studies
Hayashibara, KC; Verdine, GL	1
Lutze, LH; Morgan, WF; Phillips, JW; Winegar, RA	1
Jones, PA; Kautiainen, TL	1
Holliday, R	1
Gunter, KC; Sneller, MC	1
Jones, PA; Michalowsky, LA	2
Veselý, J	1
Farooq, M; Holliday, R; Hunter, JL; Matsumura, T	1
Bouchard, J; Chabot, GG; Momparler, RL	1
Jones, PA; Momparler, RL; Wilson, VL	1
Christman, JK	1
Flatau, E; Gonzales, FA; Jones, PA; Michalowsky, LA	1
Baylin, SB; Davidson, NE; Ferguson, AT; Lapidus, RG	1
Baylin, SB; Burger, PC; Gabrielson, E; Herman, JG; Lee, DJ; Mao, L; Merlo, A; Sidransky, D	1
Bird, AP	1
Chen, ZJ; Pikaard, CS	1
Christiansen-Weber, T; Haas, M; Haggblom, C; Vogt, M; Yeargin, J	1
Côté, S; Momparler, RL; Sinnett, D	1
Bearzatto, A; Jiricny, J; Karran, P; Macpherson, P; Szadkowski, M	1
Bashambu, M; Singal, R; van Wert, J	1
Fujita, M; Hosokawa, M; Imai, K; Itoh, F; Kikuchi, T; Suzuki, H; Toyota, M; Yamamoto, H	1
Czyz, M; Fabianowska-Majewska, K; Wyczechowska, D	1
Giles, FJ	2
Comai, L; Davison, J; Madlung, A; Masuelli, RW; Reynolds, SH; Watson, B	1
Bertoni, F; Cotter, FE; Fu, WN; Jia, L; Kelsey, SM; McElwaine, SM; Newland, AC	1
Avila, S; Esteller, M; Fraga, MF; Guo, M; Herman, JG; Paz, MF; Pollan, M	1
Kumar, PP; Kush, A; Lakshmanan, P; Prakash, AP	1
Baylin, SB; Belinsky, SA; Herman, JG; Issa, JP; Klinge, DM; March, TH; Stidley, CA	1
Aoyama, T; Ishibe, T; Nagayama, S; Nakamura, T; Nakayama, T; Nishijo, K; Okamoto, T; Toguchida, J; Yasura, K	1
Akintola, AD; Burghardt, RC; Catania, JM; Chen, G; Crislip, ZL; Parrish, AR; Zimmer, WE	1
Bokelmann, I; Lyko, F; Mahlknecht, U; Stresemann, C	1
Wang, H; Wang, Y	1
Bosque, A; Kauder, SE; Lindqvist, A; Planelles, V; Verdin, E	1
Bettuzzi, S; Patra, SK	1
Carambula, SF; Hansen, PJ; Oliveira, LJ	1
Jagodzinski, PP; Lianeri, M; Lutkowska, A; Pietkiewicz, PP	1
Huang, X; Wang, X; Yin, J; Zhong, J	1
Czemerska, M; Grzybowska-Izydorczyk, O; Pluta, A; Robak, T; Szmigielska-Kapłon, A; Wierzbowska, A; Wolska, A	1
Baer, MR; Gojo, I	1
Bao, B; Rodriguez-Melendez, R; Zempleni, J	1
Jabbour, E; Kadia, TM; Kantarjian, H	1
Bracht, JR; Landweber, LF; Perlman, DH	1
Kone, BC; Kong, Q; Yu, Z	1
Cho, IH; Chowdhury, B; Cui, Y; Irudayaraj, J	1
Iliakis, G; Moscariello, M	1
Dolan, ME; Godley, LA; Moen, EL; Stark, AL; Zhang, W	1
Huang, Y; Rao, A	1
Sakata-Yanagimoto, M	1
Chao, MR; Chen, JL; Hsu, YW; Hu, CW; Yen, CC	1
Chevassut, T; Cho, IH; Choudhury, SR; Chowdhury, B; Cooper, B; Cui, Y; Irudayaraj, J; Lossie, AC; McGovern, A	1
DeSimone, J; Ibanez, V; Lavelle, D; Mahmud, N; Rivers, A; Ruiz, MA; Vaitkus, K	1
Levine, AJ	1
Cummings-Lorbetskie, C; Desaulniers, D; Parfett, C; Xiao, GH; Zhou, G	1
Barros-Silva, D; Carneiro, I; Correia, MP; Costa, BM; Gonçalves, CS; Henrique, R; Jerónimo, C; Lobo, J; Martins, EP; Morais, A; Moreira-Silva, F; Outeiro-Pinho, G	1

Reviews

10 review(s) available for cytosine and decitabine

Article	Year
DNA methylation in friend erythroleukemia cells: the effects of chemically induced differentiation and of treatment with inhibitors of DNA methylation. Current topics in microbiology and immunology, 1984, Volume: 108 Topics: 5-Methylcytosine; Animals; Azacitidine; Cell Differentiation; Cell Line; Cytosine; Decitabine; DNA (Cytosine-5-)-Methyltransferases; DNA, Neoplasm; Friend murine leukemia virus; Gene Expression Regulation; Globins; Leukemia, Erythroblastic, Acute; Methylation; Mice	1984
The relationship of DNA methylation to cancer. Cancer surveys, 1996, Volume: 28 Topics: 5-Methylcytosine; Azacitidine; CpG Islands; Cytosine; Decitabine; DNA Methylation; Enzyme Inhibitors; Gene Expression Regulation, Neoplastic; Genes, Tumor Suppressor; Humans; Methyltransferases; Neoplasms	1996
Novel agents for the therapy of acute leukemia. Current opinion in oncology, 2002, Volume: 14, Issue:1 Topics: Angiogenesis Inhibitors; Antineoplastic Agents; Azacitidine; Cysteine Endopeptidases; Cytosine; Decitabine; Dioxolanes; DNA Methylation; Humans; Leukemia; Multienzyme Complexes; Neovascularization, Pathologic; Proteasome Endopeptidase Complex	2002
New drugs in acute myeloid leukemia. Current oncology reports, 2002, Volume: 4, Issue:5 Topics: Acute Disease; Adenine Nucleotides; Angiogenesis Inhibitors; Antibodies, Monoclonal; Antibodies, Monoclonal, Humanized; Antimetabolites, Antineoplastic; Antineoplastic Agents; Arabinonucleosides; Azacitidine; Bevacizumab; Boronic Acids; Bortezomib; Clofarabine; Cytosine; Decitabine; Dioxolanes; Humans; Indoles; Leukemia, Myeloid; Phthalazines; Pyrazines; Pyridines; Pyrroles; Thionucleotides	2002
Epigenetic DNA-(cytosine-5-carbon) modifications: 5-aza-2'-deoxycytidine and DNA-demethylation. Biochemistry. Biokhimiia, 2009, Volume: 74, Issue:6 Topics: 5-Methylcytosine; Animals; Antimetabolites, Antineoplastic; Azacitidine; Cell Cycle; Cytosine; Decitabine; DNA (Cytosine-5-)-Methyltransferases; DNA Methylation; DNA-Cytosine Methylases; Epigenesis, Genetic; Gene Expression Regulation; Humans	2009
Novel and emerging drugs for acute myeloid leukemia: pharmacology and therapeutic activity. Current medicinal chemistry, 2011, Volume: 18, Issue:5 Topics: Adenine Nucleotides; Animals; Arabinonucleosides; Azacitidine; Benzamides; Clofarabine; Cytarabine; Cytosine; Daunorubicin; Decitabine; Dioxolanes; Farnesyltranstransferase; Histone Deacetylase Inhibitors; Humans; Hydrazines; Imatinib Mesylate; Leukemia, Myeloid, Acute; Liposomes; Piperazines; Protein Kinase Inhibitors; Pyrimidines; Sulfonamides; TOR Serine-Threonine Kinases; Valproic Acid; Vascular Endothelial Growth Factor Receptor-1	2011
Failure of hypomethylating agent-based therapy in myelodysplastic syndromes. Seminars in oncology, 2011, Volume: 38, Issue:5 Topics: Adenine Nucleotides; Alemtuzumab; Antibodies, Monoclonal; Antibodies, Monoclonal, Humanized; Antibodies, Neoplasm; Antineoplastic Agents; Arabinonucleosides; Azacitidine; Clofarabine; Cytosine; Decitabine; Drug Resistance; Drug Substitution; Enzyme Inhibitors; Glutathione; Glycine; Humans; Myelodysplastic Syndromes; Stem Cell Transplantation; Sulfones; Treatment Failure	2011
Connections between TET proteins and aberrant DNA modification in cancer. Trends in genetics : TIG, 2014, Volume: 30, Issue:10 Topics: 5-Methylcytosine; Azacitidine; Cytosine; Decitabine; Dioxygenases; DNA Methylation; DNA Modification Methylases; DNA-Binding Proteins; Hematologic Neoplasms; Humans; Isocitrate Dehydrogenase; Mixed Function Oxygenases; Molecular Targeted Therapy; Mutation; Neoplasms; Proto-Oncogene Proteins; Small Molecule Libraries	2014
[TET2 dysregulation in hematologic malignancies]. [Rinsho ketsueki] The Japanese journal of clinical hematology, 2014, Volume: 55, Issue:10 Topics: Azacitidine; Cytosine; Decitabine; Dioxygenases; DNA-Binding Proteins; Enzyme Inhibitors; Epigenesis, Genetic; Genetic Predisposition to Disease; Hematologic Neoplasms; Humans; Methylation; Molecular Targeted Therapy; Multigene Family; Mutation; Neoplasm Proteins; Proto-Oncogene Proteins	2014
The p53 protein plays a central role in the mechanism of action of epigentic drugs that alter the methylation of cytosine residues in DNA. Oncotarget, 2017, Jan-31, Volume: 8, Issue:5 Topics: Animals; Antimetabolites, Antineoplastic; Azacitidine; Cell Death; Cytosine; Decitabine; DNA Methylation; DNA, Neoplasm; Drug Resistance, Neoplasm; Epigenesis, Genetic; Humans; Mutation; Neoplasms; Tumor Suppressor Protein p53	2017

Trials

1 trial(s) available for cytosine and decitabine

Article	Year
Azacytidine causes complex DNA methylation responses in myeloid leukemia. Molecular cancer therapeutics, 2008, Volume: 7, Issue:9 Topics: Antineoplastic Agents; Azacitidine; Cell Line, Tumor; Cytosine; Decitabine; DNA Methylation; Genome, Human; Humans; Leukemia, Myeloid; Myelodysplastic Syndromes; Oligonucleotide Array Sequence Analysis	2008

Other Studies

45 other study(ies) available for cytosine and decitabine

Article	Year
Template-directed interference footprinting of cytosine contacts in a protein-DNA complex: potent interference by 5-aza-2'-deoxycytidine. Biochemistry, 1992, Nov-24, Volume: 31, Issue:46 Topics: Antineoplastic Agents; Azacitidine; Base Sequence; Cytosine; Decitabine; DNA; DNA-Binding Proteins; Electrophoresis, Polyacrylamide Gel; Molecular Sequence Data; Templates, Genetic; X-Ray Diffraction	1992
Chromosome aberration induction in Chinese hamster ovary cells by restriction enzymes with different methylation sensitivity. Somatic cell and molecular genetics, 1990, Volume: 16, Issue:3 Topics: Animals; Azacitidine; Cell Line; Chromosome Aberrations; Cricetinae; Cytosine; Decitabine; Deoxyribonuclease HpaII; Deoxyribonucleases, Type II Site-Specific; DNA; Methylation; Substrate Specificity	1990
DNA methyltransferase levels in tumorigenic and nontumorigenic cells in culture. The Journal of biological chemistry, 1986, Feb-05, Volume: 261, Issue:4 Topics: 5-Methylcytosine; Animals; Azacitidine; Cattle; Cells, Cultured; Cricetinae; Cytosine; Decitabine; DNA; DNA (Cytosine-5-)-Methyltransferases; DNA, Neoplasm; Fibroblasts; Gene Expression Regulation; Humans; Mesocricetus; Methylation; Mice; Neoplasm Proteins; Neoplasms, Experimental; Rats	1986
Strong effects of 5-azacytidine on the in vitro lifespan of human diploid fibroblasts. Experimental cell research, 1986, Volume: 166, Issue:2 Topics: 5-Methylcytosine; Azacitidine; Cell Division; Cell Line; Cell Survival; Cytarabine; Cytosine; Decitabine; DNA; Fibroblasts; Humans; Methylation	1986
DNA methylation alters chromatin structure and regulates Thy-1 expression in EL-4 T cells. Journal of immunology (Baltimore, Md. : 1950), 1987, May-15, Volume: 138, Issue:10 Topics: 5-Methylcytosine; Animals; Antigens, Surface; Azacitidine; Cell Line; Chromatin; Cytosine; Decitabine; DNA, Neoplasm; Ethyl Methanesulfonate; Gene Expression Regulation; Lymphoma; Methylation; Mice; Mice, Inbred C57BL; RNA, Messenger; T-Lymphocytes; Thy-1 Antigens	1987
Differential nuclear protein binding to 5-azacytosine-containing DNA as a potential mechanism for 5-aza-2'-deoxycytidine resistance. Molecular and cellular biology, 1987, Volume: 7, Issue:9 Topics: 5-Methylcytosine; Animals; Azacitidine; Cell Line; Cell Nucleus; Cytarabine; Cytosine; Decitabine; DNA; DNA (Cytosine-5-)-Methyltransferases; DNA-Binding Proteins; Drug Resistance; Methylation; Mice	1987
High degree of resistance to 5-aza-2'-deoxycytidine in L1210 cells in vitro associated with almost complete loss of deoxycytidine kinase activity. Neoplasma, 1987, Volume: 34, Issue:6 Topics: 5-Methylcytosine; Animals; Azacitidine; Cell Line; Cells, Cultured; Cytosine; Decitabine; Deoxycytidine; Deoxycytidine Kinase; DNA (Cytosine-5-)-Methyltransferases; Drug Resistance; Leukemia L1210; Mice; Phosphorylation; Phosphotransferases	1987
Gene structure and transcription in mouse cells with extensively demethylated DNA. Molecular and cellular biology, 1989, Volume: 9, Issue:3 Topics: 5-Methylcytosine; Animals; Azacitidine; Chromatin; Clone Cells; Cytosine; Decitabine; DNA; Gene Expression Regulation; Methylation; Mice; Transcription, Genetic	1989
Maintenance of DNA methylation level in SV40-infected human fibroblasts during their in vitro limited proliferative life span. Experimental cell research, 1989, Volume: 184, Issue:1 Topics: 5-Methylcytosine; Azacitidine; Base Composition; Cell Division; Cell Transformation, Viral; Cytosine; Decitabine; DNA; Humans; In Vitro Techniques; Methylation; Simian virus 40	1989
Kinetics of deamination of 5-aza-2'-deoxycytidine and cytosine arabinoside by human liver cytidine deaminase and its inhibition by 3-deazauridine, thymidine or uracil arabinoside. Biochemical pharmacology, 1983, Apr-01, Volume: 32, Issue:7 Topics: 3-Deazauridine; Adult; Arabinofuranosyluracil; Azacitidine; Cytarabine; Cytidine Deaminase; Cytosine; Decitabine; Humans; Kinetics; Liver; Nucleoside Deaminases; Substrate Specificity; Thymidine	1983
Inhibition of DNA methylation in L1210 leukemic cells by 5-aza-2'-deoxycytidine as a possible mechanism of chemotherapeutic action. Cancer research, 1983, Volume: 43, Issue:8 Topics: 5-Methylcytosine; Animals; Antineoplastic Agents; Azacitidine; Cytosine; Decitabine; DNA; DNA (Cytosine-5-)-Methyltransferases; Dose-Response Relationship, Drug; Leukemia L1210; Male; Methylation; Mice	1983
DNA methylation in 5-aza-2'-deoxycytidine-resistant variants of C3H 10T1/2 C18 cells. Molecular and cellular biology, 1984, Volume: 4, Issue:10 Topics: Animals; Azacitidine; Cell Line; Cytosine; Decitabine; DNA; Drug Resistance; Kinetics; Methylation; Mice; Mice, Inbred C3H	1984
Demethylation of the estrogen receptor gene in estrogen receptor-negative breast cancer cells can reactivate estrogen receptor gene expression. Cancer research, 1995, Jun-01, Volume: 55, Issue:11 Topics: Antineoplastic Agents; Azacitidine; Base Sequence; Breast Neoplasms; Cytosine; Decitabine; DNA, Neoplasm; Gene Expression; Gene Expression Regulation, Neoplastic; Guanine; Humans; Methylation; Molecular Sequence Data; Receptors, Estrogen; RNA, Messenger; Tumor Cells, Cultured	1995
5' CpG island methylation is associated with transcriptional silencing of the tumour suppressor p16/CDKN2/MTS1 in human cancers. Nature medicine, 1995, Volume: 1, Issue:7 Topics: 5-Methylcytosine; Alleles; Azacitidine; Base Sequence; Brain Neoplasms; Carcinoma, Non-Small-Cell Lung; Carcinoma, Squamous Cell; Carrier Proteins; Chromosomes, Human, Pair 9; CpG Islands; Cyclin-Dependent Kinase Inhibitor p16; Cytosine; Decitabine; DNA, Neoplasm; Gene Expression Regulation, Neoplastic; Genes, Tumor Suppressor; Glioma; Head and Neck Neoplasms; Humans; Lung Neoplasms; Methylation; Molecular Sequence Data; Neoplasm Proteins; Neoplasms; Sequence Deletion; Transcription, Genetic; Tumor Cells, Cultured	1995
Epigenetic silencing of RNA polymerase I transcription: a role for DNA methylation and histone modification in nucleolar dominance. Genes & development, 1997, Aug-15, Volume: 11, Issue:16 Topics: Azacitidine; Brassica; Butyrates; Butyric Acid; Cell Nucleolus; Cytosine; Decitabine; DNA Methylation; Enzyme Inhibitors; Gene Expression Regulation, Plant; Genes, Dominant; Histones; Hydroxamic Acids; Polyploidy; RNA Polymerase I; RNA, Ribosomal; Transcription, Genetic	1997
Independent induction of senescence by p16INK4a and p21CIP1 in spontaneously immortalized human fibroblasts. Cell growth & differentiation : the molecular biology journal of the American Association for Cancer Research, 1998, Volume: 9, Issue:2 Topics: 5-Methylcytosine; Azacitidine; Cell Division; Cell Line, Transformed; Cellular Senescence; CpG Islands; Cyclin-Dependent Kinase Inhibitor p16; Cyclin-Dependent Kinase Inhibitor p21; Cyclins; Cytosine; Decitabine; DNA Methylation; DNA, Complementary; Gene Expression Regulation; Genes, p16; Genes, p53; Germ-Line Mutation; Humans; Li-Fraumeni Syndrome	1998
Demethylation by 5-aza-2'-deoxycytidine of specific 5-methylcytosine sites in the promoter region of the retinoic acid receptor beta gene in human colon carcinoma cells. Anti-cancer drugs, 1998, Volume: 9, Issue:9 Topics: 5-Methylcytosine; Adenocarcinoma; Antimetabolites, Antineoplastic; Azacitidine; Base Sequence; Colonic Neoplasms; CpG Islands; Cytosine; Decitabine; DNA Methylation; DNA Primers; DNA, Neoplasm; Humans; Molecular Sequence Data; Polymerase Chain Reaction; Promoter Regions, Genetic; Receptors, Retinoic Acid; Tumor Cells, Cultured	1998
Epigenetic regulation of the MGMT and hMSH6 DNA repair genes in cells resistant to methylating agents. Cancer research, 2000, Jun-15, Volume: 60, Issue:12 Topics: Alkylating Agents; Antimetabolites, Antineoplastic; Azacitidine; Blotting, Western; CpG Islands; Cytosine; Decitabine; DNA Methylation; DNA Repair; DNA-Binding Proteins; Dose-Response Relationship, Drug; Drug Resistance, Neoplasm; Gene Silencing; Humans; Luciferases; Methylnitrosourea; O(6)-Methylguanine-DNA Methyltransferase; Plasmids; Promoter Regions, Genetic; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Sequence Analysis, DNA; Transcription, Genetic; Transfection; Tumor Cells, Cultured	2000
Cytosine methylation represses glutathione S-transferase P1 (GSTP1) gene expression in human prostate cancer cells. Cancer research, 2001, Jun-15, Volume: 61, Issue:12 Topics: Azacitidine; Base Sequence; Cytosine; Decitabine; DNA Methylation; Enzyme Inhibitors; Gene Expression Regulation, Enzymologic; Gene Expression Regulation, Neoplastic; Gene Silencing; Glutathione S-Transferase pi; Glutathione Transferase; HeLa Cells; Histone Deacetylase Inhibitors; Humans; Hydroxamic Acids; Isoenzymes; Male; Molecular Sequence Data; Plasmids; Promoter Regions, Genetic; Prostatic Neoplasms; Transfection; Tumor Cells, Cultured	2001
Aberrant methylation and histone deacetylation of cyclooxygenase 2 in gastric cancer. International journal of cancer, 2002, Jan-20, Volume: 97, Issue:3 Topics: Antimetabolites, Antineoplastic; Apoptosis; Azacitidine; Cyclooxygenase 2; Cytosine; Decitabine; DNA; DNA Methylation; Enzyme Inhibitors; Gastric Mucosa; Gene Silencing; Histone Deacetylases; Histones; Humans; Hydroxamic Acids; Immunohistochemistry; Isoenzymes; Membrane Proteins; Methylation; Polymorphism, Single-Stranded Conformational; Precipitin Tests; Promoter Regions, Genetic; Prostaglandin-Endoperoxide Synthases; Reverse Transcriptase Polymerase Chain Reaction; Stomach Neoplasms; Sulfites; Transcription, Genetic; Tumor Cells, Cultured	2002
Inhibition of dna methylation by 5-aza-2'-deoxycytidine correlates with induction of K562 cells differentiation. Advances in experimental medicine and biology, 2000, Volume: 486 Topics: Antimetabolites, Antineoplastic; Azacitidine; Butyric Acid; Cell Differentiation; CpG Islands; Cytosine; Decitabine; DNA Methylation; DNA Modification Methylases; Enzyme Inhibitors; Humans; K562 Cells	2000
Remodeling of DNA methylation and phenotypic and transcriptional changes in synthetic Arabidopsis allotetraploids. Plant physiology, 2002, Volume: 129, Issue:2 Topics: Arabidopsis; Azacitidine; Chromatin; Crosses, Genetic; Cytosine; Decitabine; DNA Methylation; DNA-Cytosine Methylases; DNA, Complementary; Evolution, Molecular; Gene Expression Regulation; Gene Silencing; Phenotype; Polymorphism, Restriction Fragment Length; Polyploidy; RNA, Messenger	2002
Role of DNA methylation in the suppression of Apaf-1 protein in human leukaemia. Oncogene, 2003, Jan-23, Volume: 22, Issue:3 Topics: Apoptosis; Apoptotic Protease-Activating Factor 1; Azacitidine; Cytosine; Decitabine; DNA Methylation; Humans; Leukemia; Polymerase Chain Reaction; Promoter Regions, Genetic; Proteins; Reference Values; Sequence Analysis, DNA; Tumor Cells, Cultured; Ultraviolet Rays	2003
A systematic profile of DNA methylation in human cancer cell lines. Cancer research, 2003, Mar-01, Volume: 63, Issue:5 Topics: 5-Methylcytosine; Azacitidine; Cluster Analysis; CpG Islands; Cytosine; Decitabine; DNA Methylation; DNA, Neoplasm; Genes, Tumor Suppressor; Germ-Line Mutation; Humans; Neoplasms; Oligonucleotide Array Sequence Analysis; Tumor Cells, Cultured	2003
Cytosine methylation occurs in a CDC48 homologue and a MADS-box gene during adventitious shoot induction in Petunia leaf explants. Journal of experimental botany, 2003, Volume: 54, Issue:386 Topics: Amino Acid Sequence; Azacitidine; Cloning, Molecular; Culture Techniques; Cytosine; Decitabine; DNA Methylation; DNA, Plant; Gene Expression Regulation, Plant; MADS Domain Proteins; Microscopy, Electron, Scanning; Molecular Sequence Data; Petunia; Phylogeny; Plant Leaves; Plant Shoots; Sequence Analysis, DNA; Sequence Homology, Amino Acid	2003
Inhibition of DNA methylation and histone deacetylation prevents murine lung cancer. Cancer research, 2003, Nov-01, Volume: 63, Issue:21 Topics: Alleles; Animals; Antimetabolites, Antineoplastic; Azacitidine; Cytosine; Decitabine; DNA (Cytosine-5-)-Methyltransferase 1; DNA (Cytosine-5-)-Methyltransferases; DNA Methylation; Drug Synergism; Enzyme Inhibitors; Female; Gene Dosage; Histone Deacetylase Inhibitors; Histones; Lung Neoplasms; Male; Mice; Mice, Inbred A; Phenylbutyrates	2003
Methylation in the core-promoter region of the chondromodulin-I gene determines the cell-specific expression by regulating the binding of transcriptional activator Sp3. The Journal of biological chemistry, 2004, Jul-02, Volume: 279, Issue:27 Topics: 5-Methylcytosine; Azacitidine; Binding Sites; Blotting, Western; Bone and Bones; Cartilage; Cell Line, Tumor; Chondrocytes; Chromatin; CpG Islands; Cytosine; Decitabine; DNA Methylation; DNA-Binding Proteins; Genes, Reporter; Humans; Intercellular Signaling Peptides and Proteins; Luciferases; Membrane Proteins; Precipitin Tests; Promoter Regions, Genetic; Protein Binding; Reverse Transcriptase Polymerase Chain Reaction; RNA Interference; RNA, Messenger; RNA, Small Interfering; Sp1 Transcription Factor; Sp3 Transcription Factor; Sulfites; Thymine; Transcription Factors; Transcription, Genetic	2004
Promoter methylation is associated with the age-dependent loss of N-cadherin in the rat kidney. American journal of physiology. Renal physiology, 2008, Volume: 294, Issue:1 Topics: Aging; Animals; Azacitidine; Base Sequence; Cadherins; Cells, Cultured; Cytosine; Decitabine; DNA; DNA Methylation; Enzyme Inhibitors; Gene Expression Regulation; Guanine; Kidney; Liver; Male; Molecular Sequence Data; Promoter Regions, Genetic; Rats; Rats, Inbred F344	2008
6-Thioguanine perturbs cytosine methylation at the CpG dinucleotide site by DNA methyltransferases in vitro and acts as a DNA demethylating agent in vivo. Biochemistry, 2009, Mar-17, Volume: 48, Issue:10 Topics: Azacitidine; Cytosine; Decitabine; Dinucleoside Phosphates; DNA; DNA (Cytosine-5-)-Methyltransferase 1; DNA (Cytosine-5-)-Methyltransferases; DNA Methylation; DNA-Cytosine Methylases; Humans; Jurkat Cells; Oligodeoxyribonucleotides; Tandem Mass Spectrometry; Thioguanine	2009
Epigenetic regulation of HIV-1 latency by cytosine methylation. PLoS pathogens, 2009, Volume: 5, Issue:6 Topics: Azacitidine; CD4-Positive T-Lymphocytes; CpG Islands; Cytosine; Decitabine; DNA Methylation; DNA-Binding Proteins; Epigenesis, Genetic; HIV-1; Humans; Jurkat Cells; NF-kappa B; Promoter Regions, Genetic; Repressor Proteins; RNA, Small Interfering; Transfection; Virus Latency	2009
Repression of induced apoptosis in the 2-cell bovine embryo involves DNA methylation and histone deacetylation. Biochemical and biophysical research communications, 2009, Oct-16, Volume: 388, Issue:2 Topics: 5-Methylcytosine; Animals; Apoptosis; Azacitidine; Blastocyst; Carbonyl Cyanide m-Chlorophenyl Hydrazone; Cattle; Cytosine; Decitabine; DNA Fragmentation; DNA Methylation; Histone Deacetylase Inhibitors; Histone Deacetylases; Histones; Hydroxamic Acids	2009
Tamoxifen epigenetically modulates CXCL12 expression in MCF-7 breast cancer cells. Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie, 2010, Volume: 64, Issue:1 Topics: Antimetabolites, Antineoplastic; Antineoplastic Agents, Hormonal; Azacitidine; Breast Neoplasms; Cell Line, Tumor; Chemokine CXCL12; Cytosine; Decitabine; DNA Methylation; Epigenesis, Genetic; Female; Gene Expression Regulation, Neoplastic; Humans; Sequence Analysis, DNA; Tamoxifen	2010
DNA methyltransferase inhibitors increase baculovirus-mediated gene expression in mammalian cells when applied before infection. Analytical biochemistry, 2010, Jan-15, Volume: 396, Issue:2 Topics: Animals; Azacitidine; Baculoviridae; Cell Line; CHO Cells; Cricetinae; Cricetulus; Cytosine; Decitabine; DNA (Cytosine-5-)-Methyltransferases; Enzyme Inhibitors; Gene Expression Regulation; Genetic Vectors; Humans	2010
Novel agents for the treatment of acute myeloid leukemia in the older patient. Journal of the National Comprehensive Cancer Network : JNCCN, 2011, Volume: 9, Issue:3 Topics: Adenine Nucleotides; Age Factors; Aged; Antineoplastic Agents; Arabinonucleosides; Azacitidine; Clofarabine; Cytosine; Decitabine; Disease-Free Survival; Hematopoietic Stem Cell Transplantation; Humans; Lenalidomide; Leukemia, Myeloid, Acute; Middle Aged; Prognosis; Quinolones; Thalidomide	2011
Cytosine methylation in miR-153 gene promoters increases the expression of holocarboxylase synthetase, thereby increasing the abundance of histone H4 biotinylation marks in HEK-293 human kidney cells. The Journal of nutritional biochemistry, 2012, Volume: 23, Issue:6 Topics: 3' Untranslated Regions; Azacitidine; Binding Sites; Biotinylation; Carbon-Nitrogen Ligases; Cytosine; Decitabine; DNA Methylation; Epigenomics; Gene Expression Regulation; HEK293 Cells; Histones; Humans; Kidney; MicroRNAs; Promoter Regions, Genetic	2012
Cytosine methylation and hydroxymethylation mark DNA for elimination in Oxytricha trifallax. Genome biology, 2012, Oct-17, Volume: 13, Issue:10 Topics: Azacitidine; Cytosine; Decitabine; DNA Methylation; DNA, Protozoan; Enzyme Inhibitors; Gene Rearrangement; High-Throughput Nucleotide Sequencing; Mass Spectrometry; Molecular Sequence Data; Oxytricha; Sequence Analysis, DNA	2012
Aldosterone reprograms promoter methylation to regulate αENaC transcription in the collecting duct. American journal of physiology. Renal physiology, 2013, Oct-01, Volume: 305, Issue:7 Topics: Aldosterone; Animals; Azacitidine; Cell Line; Cells, Cultured; Cytosine; Decitabine; Dioxygenases; DNA (Cytosine-5-)-Methyltransferases; DNA Methylation; DNA Methyltransferase 3B; DNA-Binding Proteins; Endodeoxyribonucleases; Epithelial Sodium Channels; Kidney Tubules, Collecting; Mice; Promoter Regions, Genetic; Proto-Oncogene Proteins; Sp1 Transcription Factor; Transcription, Genetic	2013
Real-time dynamics of methyl-CpG-binding domain protein 3 and its role in DNA demethylation by fluorescence correlation spectroscopy. Epigenetics, 2013, Volume: 8, Issue:10 Topics: 5-Methylcytosine; Azacitidine; Cell Hypoxia; Cytosine; Decitabine; DNA; DNA Modification Methylases; DNA-Binding Proteins; HeLa Cells; Humans; Single-Cell Analysis; Spectrometry, Fluorescence	2013
Effects of chromatin decondensation on alternative NHEJ. DNA repair, 2013, Volume: 12, Issue:11 Topics: Animals; Azacitidine; Cell Cycle; Cell Line; Chromatin; Chromosomal Instability; Cytosine; Decitabine; DNA Breaks, Double-Stranded; DNA End-Joining Repair; DNA Ligases; DNA Methylation; Gene Expression Regulation; Humans; Hypotonic Solutions; Mice; Translocation, Genetic	2013
The role of gene body cytosine modifications in MGMT expression and sensitivity to temozolomide. Molecular cancer therapeutics, 2014, Volume: 13, Issue:5 Topics: Antineoplastic Agents, Alkylating; Azacitidine; Cell Line, Tumor; CpG Islands; Cytosine; Dacarbazine; Decitabine; DNA Methylation; DNA Modification Methylases; DNA Repair Enzymes; Drug Resistance, Neoplasm; Gene Expression Regulation, Neoplastic; Glioblastoma; Humans; Polymorphism, Single Nucleotide; Promoter Regions, Genetic; Quantitative Trait Loci; Temozolomide; Tumor Suppressor Proteins	2014
Trace analysis of methylated and hydroxymethylated cytosines in DNA by isotope-dilution LC-MS/MS: first evidence of DNA methylation in Caenorhabditis elegans. The Biochemical journal, 2015, Jan-01, Volume: 465, Issue:1 Topics: 5-Methylcytosine; Animals; Azacitidine; Cadmium; Caenorhabditis elegans; Chromatography, Liquid; Cytosine; Decitabine; Deoxycytidine; DNA; DNA Methylation; Isotope Labeling; Online Systems; Reproducibility of Results; Solid Phase Extraction; Tandem Mass Spectrometry	2015
The hypomethylating agent Decitabine causes a paradoxical increase in 5-hydroxymethylcytosine in human leukemia cells. Scientific reports, 2015, Apr-22, Volume: 5 Topics: 5-Methylcytosine; Azacitidine; Catalytic Domain; Chromatography, High Pressure Liquid; CpG Islands; Cytosine; Decitabine; DNA (Cytosine-5-)-Methyltransferases; DNA Methylation; DNA-Binding Proteins; Enzyme-Linked Immunosorbent Assay; HL-60 Cells; Humans; Immunohistochemistry; Leukemia, Myeloid, Acute; MCF-7 Cells; Microscopy, Fluorescence; Mixed Function Oxygenases; Protein Binding; Proto-Oncogene Proteins; Spectrometry, Fluorescence; Tandem Mass Spectrometry	2015
Hydroxymethylcytosine and demethylation of the γ-globin gene promoter during erythroid differentiation. Epigenetics, 2015, Volume: 10, Issue:5 Topics: 5-Methylcytosine; Animals; Animals, Newborn; Antineoplastic Agents; Ascorbic Acid; Azacitidine; Bone Marrow Cells; Cell Differentiation; Cells, Cultured; Cytosine; Decitabine; Dioxygenases; DNA Methylation; Erythroid Cells; gamma-Globins; Histone Demethylases; Humans; Hydroxyurea; Liver; Papio anubis; Promoter Regions, Genetic; Tranylcypromine	2015
Two-color fluorescent cytosine extension assay for the determination of global DNA methylation. BioTechniques, 2017, 04-01, Volume: 62, Issue:4 Topics: Azacitidine; Biological Assay; Cytosine; Decitabine; DNA Methylation; DNA Restriction Enzymes; Fluorescence; Hep G2 Cells; Humans; Liver; Primary Cell Culture	2017
Epigenetically-regulated miR-30a/c-5p directly target TWF1 and hamper ccRCC cell aggressiveness. Translational research : the journal of laboratory and clinical medicine, 2022, Volume: 249 Topics: Carcinoma, Renal Cell; Cell Line, Tumor; Cell Movement; Cell Proliferation; Claudin-1; Cytosine; Decitabine; Epigenesis, Genetic; Gene Expression Regulation, Neoplastic; Guanine; Humans; Kidney Neoplasms; Luciferases; Microfilament Proteins; MicroRNAs; Phosphates; Protein-Tyrosine Kinases; RNA, Small Interfering	2022