cytosine and cmx 001

cytosine has been researched along with cmx 001 in 103 studies

Research

Studies (103)

Timeframe	Studies, this research(%)	All Research%
pre-1990	0 (0.00)	18.7374
1990's	0 (0.00)	18.2507
2000's	5 (4.85)	29.6817
2010's	83 (80.58)	24.3611
2020's	15 (14.56)	2.80

Authors

Authors	Studies
Hruby, DE; Jordan, R; Keith, KA; Kern, ER; Painter, GR; Prichard, MN; Quenelle, DC; Robertson, A	1
Almond, M; Buller, RM; Lampert, B; Oberle, C; Painter, G; Parker, S; Robertson, A; Touchette, E; Trost, LC	1
Buller, RM; Dhar, D; Painter, GR; Sagartz, JE; Spencer, JF; Toth, K; Wold, WS	1
Buller, RM; Lanier, R; Oberle, C; Painter, G; Parker, S; Robertson, A; Schriewer, J	1
Buller, RM; Hembrador, E; Lanier, R; Oberle, C; Painter, G; Parker, S; Robertson, A; Siddiqui, AM	1
Buller, RM; Parker, S; Sagartz, JE; Schriewer, J; Stabenow, J; West, C	1
Bernhoff, E; Finstad, S; Gosert, R; Hirsch, HH; Rinaldo, CH	1
Cohen, J; Jiang, ZG; Major, EO; Marshall, LJ	1
Ikwuagwu, J; Patel, A; Patel, J	1
Collins, DJ; Kern, ER; Lampert, B; Painter, GR; Quenelle, DC; Rice, TL	1
Bellone, CJ; Buller, RM; Chen, N; Fredrickson, T; Owens, G; Parker, S; Schriewer, J	1
Beadle, JR; Bernstein, DI; Bravo, FJ; Cardin, RD; Hostetler, KY	1
Anderson, M; DeBiasi, RL; Fry, T; Jantausch, B; Lanier, ER; Loechelt, B; Painter, W; Paolino, K; Perez, E; Sande, J; Tippin, T	1
Adams, MM; Foster, S; Lampert, B; Moyer, RW; Painter, G; Rice, AD; Robertson, A	1
Adams, MM; Burrage, AM; Foster, S; Gray, SA; Lampert, B; Lanier, R; Lindsey, SF; Manning, BR; Moyer, RW; Painter, G; Rice, AD; Robertson, A; Smith, AJ; Swetnam, D; Wallace, G	1
Gosert, R; Hirsch, HH; Major, EO; Rinaldo, CH; Wernli, M	1
Hartline, CB; Kern, ER; Lanier, ER; Prichard, MN; Quenelle, DC	1
Hayden, EC	1
Anderson, M; Florescu, DF; Graham, ML; Guzman-Cottrill, JA; Johnston, C; Kurtzberg, J; Lanier, R; Lewinsohn, DA; Mommeja-Marin, H; Neely, MN; Painter, W; Papanicolaou, G; Pergam, SA; Qiu, F; Rigdon, J; Sande, J; van der Horst, C; Way, S	1
Vere Hodge, A	1
Aldern, KA; Beadle, JR; Cheng, L; Chhablani, J; Conner, L; Freeman, WR; Hartmann, K; Hostetler, KY; Pearson, L; Wang, H	1
Ali, MA; Cohen, JI; Cowen, EW; Davila, W; Freeman, AF; Turk, SP; Wang, K	1
Chen, NG; Foster, S; Hartzler, H; Hembrador, E; Hruby, D; Jordan, R; Lanier, R; Mark Buller, R; Painter, G; Painter, W; Parker, S; Sagartz, JE; Schriewer, J	1
Godkin, S; Lampert, B; Painter, G; Painter, W; Robertson, A; Trost, LC	1
Ahmed, R; Akondy, RS; Bergman, KL; Cohen, JI; Damon, IK; Davidson, W; Frace, M; Groff, HL; Hruby, DE; Karem, KL; Lederman, ER; Li, Y; Painter, WP; Shieh, WJ; Smith, SK; Warkentien, T; Wilkins, KA; Zaki, S	1
Agut, H; Bogaert, S; Bonnafous, P; Godet, AN	1
Alfson, ED; Awosika, OO; Ciarlini, P; Drew, C; Folkerth, RD; Johnson, EL; Klein, JP; Koo, S; Lyons, JL; Marty, F; Phillips, RE; Zaki, S	1
Hartline, CB; James, SH; Lanier, ER; Price, NB; Prichard, MN	1
Boeckh, M; Brundage, TM; Godkin, S; Marty, FM; Momméja-Marin, H; Mullane, KM; Papanicolaou, GA; Robertson, AT; Rowley, SD; Vance, E; Winston, DJ	1
Boztug, H; Lion, T; Matthes-Martin, S	1
Peggs, KS; Sellar, RS	1
Damon, IK; Foster, S; Gates, I; Lanier, ER; Li, Y; Olson, VA; Smith, SK; Trost, LC	1
Florescu, DF; Keck, MA	1
Buller, RM; Crump, R; Foster, S; Hartzler, H; Hembrador, E; Lanier, ER; Painter, G; Parker, S; Schriewer, J; Trost, LC	1
Habib, S; Latiolais, LS; McClure, GB; Reisman, L; Vanchiere, JA	1
Balakrishnan, L; Buller, RM; Capella, C; Dewhurst, S; Spencer, JF; Tollefson, AE; Toth, K; Wold, WS; Ying, B	1
Griffiths, P; Lumley, S	1
Cohen, J; Kupferschmidt, K	2
Boeckh, M; Murphy, WJ; Peggs, KS	1
Buller, RM; Spencer, JF; Tollefson, AE; Toth, K; Wold, WS; Ying, B	1
Beadle, JR; Cheng, L; Freeman, WR; Hostetler, KY; Hou, H; Lee, S; Ma, F; Nan, K	1
Nau, JY	1
Cruz, S; Diaz, CG; Golding, H; Grossi, IM; Keilholz, L; McCullough, KT; Thomas, A; Trost, LC; Zaitseva, M	1
Boruchov, AM; Chittick, G; Glezerman, IG; Lee, YJ; Momméja-Marin, H; Papanicolaou, GA; Seshan, SV; Young, JW	1
Foster, SA; Godin, SJ; Keilholz, L; Khouri, J; Long, J; Rose, ML; Trost, LC	1
Hirsch, HH; Rinaldo, CH; Tylden, GD	1
Bavari, S; Cardile, AP; Mayers, DL	1
Bekerman, E; Einav, S	1
Florescu, DF; Hewlett, AL; Kalil, AC; Schuh, AJ; Smith, PW; Stroher, U; Uyeki, TM	1
Lang, T	1
Blondiaux, J; Haque, A; Hober, D	1
Toth, K; Wold, WS	1
Breuer, J; De, SK; Hart, JC	1
Albariño, C; Dyall, J; Flint, M; Foster, S; Hensley, LE; Lanier, ER; McMullan, LK; Nichol, ST; Olinger, GG; Sethna, P; Spiropoulou, CF	1
Cohen, J; Enserink, M	1
Horby, P; Lang, T; Olliaro, P; Whitehead, J	1
Chou, S; Ercolani, RJ; Lanier, ER	1
Gill, JS; Wright, AJ	1
Reardon, S	1
Hartline, CB; Larson, RA; Mommeja-Marin, H; Mullane, KM; Nuss, C; Prichard, MN; Ridgeway, J; Theusch, J	1
Edelmann, A; Hofmann, J; Kühl, JS; Sauerbrei, A; Voigt, S	1
Gerna, G; Lilleri, D	1
Abbo, LM; Alencar, MC; Camargo, JF; Komanduri, KV; Lekakis, LJ; Morris, MI; Saneeymehri, S; Simkins, J	1
Ariza-Heredia, EJ; Chemaly, RF; El Chaer, F; El-Haddad, D; Gulbis, AM; Mulanovich, VE; Shah, DP; Shpall, EJ; Vanichanan, J	1
Antierens, A; Carson, G; Castle, L; Ciglenecki, I; Dunning, J; Grove, J; Horby, PW; Howell-Jones, R; Kanapathipillai, R; Kennedy, SB; Lang, T; Olliaro, P; Pardinaz-Solis, R; Scott, J; Whitehead, J	1
Hayden, RT; Ison, MG	1
Brundage, TM; Momméja-Marin, H; Morrison, ME; Tippin, TK	1
Alain, S; Béné, J; Cannesson, O; Dewilde, A; Faure, E; Galperine, T; Gnemmi, V; Goeminne, C; Lasri, M; Lessore de Sainte Foy, C; Lionet, A	1
Buller, RM; Crump, R; Korom, M; Parker, S	1
Brundage, T; Chittick, G; Morrison, M; Nichols, WG	1
El Hayderi, L; Nikkels, AF; Rübben, A	1
Brundage, T; Dunn, JA; Foster, SA; Gainey, MR; Grossi, IM; Khouri, JM; Krile, RT	1
Spencer, JF; Tollefson, AE; Toth, K; Wold, WSM; Ying, B	1
Attwood, C; Griffiths, PD; Irish, D; Kyriakou, C; Lowe, DM; Ramsay, ID	1
Abouljoud, MS; Nagai, S; Ramesh, M; Raoufi, M; Rizzari, MD; Safwan, M; Sulejmani, N	1
Frange, P; Leruez-Ville, M	1
Amit, S; Averbuch, D; Cherniak, M; Dar, D; Safadi, R; Sorek, R; Wolf, D	1
Foster, SA; Lanier, R; Parker, S	1
Green, M; Lopez, SMC; Michaels, MG	1
Cardona, DM; Detweiler, CJ; Mueller, SB; Prasad, VK; Saullo, JL; Sung, AD	1
Cheteyan, L; Huang, YT; Jakubowski, AA; Kim, SJ; Lee, YJ; Neofytos, D; Papadopoulos, EB; Papanicolaou, GA	1
DeVita, AV; Gentry, BG; Markovich, KC; O'Brien, MS; Selleseth, D; Sethna, P	1
Boeckh, MJ; Brundage, TM; Chemaly, RF; Chittick, G; Foster, SA; Marty, FM; Morrison, ME; Mullane, KM; Nichols, WG; Papanicolaou, GA; Shore, TB; Wilson, C; Winston, DJ	1
Bae, A; Bambara, RA; Chamberlain, JM; Dewhurst, S; Lanier, R; Sethna, P; Sortino, K	1
Kinsey, S; Meena, JP; Phillips, RS	1
Bar-On, S; Haynes, RK; Lantsberg, D; Laskov, I; Oiknine-Djian, E; Panet, A; Wolf, DG	1
Delaune, D; Iseni, F	1
Berthou, C; Eveillard, JR; Rezig, S; Talarmin, JP; Tran-Minoui, A	1
Boeckh, MJ; Brundage, TM; Hill, JA; Lanier, R; Marty, FM; Nichols, WG; Papanicolaou, GA; Zerr, DM	1
Alvarez-Cardona, JJ; Chemaly, RF; Whited, LK	1
Ljungman, P	1
Garro, R; George, RP; Liverman, R; Londeree, J; Romero, R; Serluco, A; Shin, S; Winterberg, PD; Yildirim, I	1
Armero, A; Dalle, JH; Diaz, E; Dutrieux, J; Feghoul, L; LeGoff, J; Mercier-Delarue, S; Salmona, M; Splitberger, M	1
Cottrell, ML; Dunn, JA; Guzman, BB; Schauer, AP; Sykes, C	1
Richardson, BE	1
Buller, RM; D'Angelo, J; George, SL; Jensen, A; Lantto, J; Nielsen, H; Parker, S; Prichard, M; Smee, DF	1
Bensman, T; Birnkrant, D; Cao, Y; Chan-Tack, K; Choi, SY; Donaldson, E; Ghantous, H; Harrington, P; McMillan, D; Myers, L; O'Rear, J; Seaton, M; Struble, K; Valappil, T	1
Baretta, V; Biffi, A; Calore, E; Caniglia, M; Capolsini, I; Carraro, F; Cesaro, S; Fagioli, F; Faraci, M; Galaverna, F; Locatelli, F; Massei, MS; Menconi, M; Pagliara, D; Perruccio, K; Soncini, E; Verna, M	1
Fujimoto, T; Fukushima, K; Hanaoka, N; Hazama, M	1
Sassine, J; Siegrist, EA	1
Curtis, S; Egelund, EF; Huston, J	1

Reviews

21 review(s) available for cytosine and cmx 001

Article	Year
Efficacy of CMX001 as a prophylactic and presymptomatic antiviral agent in New Zealand white rabbits infected with rabbitpox virus, a model for orthopoxvirus infections of humans. Viruses, 2011, Volume: 3, Issue:2 Topics: Animals; Antiviral Agents; Bioterrorism; Cytosine; Disease Models, Animal; Disease Transmission, Infectious; Humans; Mpox (monkeypox); Organophosphonates; Rabbits; Smallpox; Smallpox Vaccine; Vaccinia virus	2011
Efficacy of CMX001 as a post exposure antiviral in New Zealand White rabbits infected with rabbitpox virus, a model for orthopoxvirus infections of humans. Viruses, 2011, Volume: 3, Issue:1 Topics: Animals; Antiviral Agents; Cytosine; Disease Models, Animal; Disease Transmission, Infectious; Dose-Response Relationship, Drug; Humans; Mpox (monkeypox); Organophosphonates; Rabbits; Random Allocation; Smallpox; Vaccinia virus	2011
Diagnosis and treatment of adenovirus infection in immunocompromised patients. Expert review of anti-infective therapy, 2013, Volume: 11, Issue:10 Topics: Adenovirus Infections, Human; Adenoviruses, Human; Adult; Antiviral Agents; Child; Cytosine; Humans; Immunocompromised Host; Incidence; Organophosphonates; Risk Factors; Stem Cell Transplantation; T-Lymphocytes; Transplantation, Homologous; Treatment Outcome; Viral Load	2013
Therapeutic strategies for cytomegalovirus infection in haematopoietic transplant recipients: a focused update. Expert opinion on biological therapy, 2014, Volume: 14, Issue:8 Topics: Acetates; Antiviral Agents; Benzimidazoles; Cytomegalovirus; Cytomegalovirus Infections; Cytosine; Hematologic Neoplasms; Hematopoietic Stem Cell Transplantation; Humans; Immunotherapy, Adoptive; Organophosphonates; Quinazolines; Ribonucleosides; T-Lymphocytes; Transplant Recipients; Transplantation, Homologous	2014
Cytomegalovirus. Current opinion in infectious diseases, 2014, Volume: 27, Issue:6 Topics: Acetates; Antiviral Agents; Benzimidazoles; Bone Marrow Transplantation; Cytomegalovirus; Cytomegalovirus Infections; Cytosine; Disease Transmission, Infectious; Double-Blind Method; Female; Ganciclovir; Humans; Male; Organ Transplantation; Organophosphonates; Practice Guidelines as Topic; Pregnancy; Pregnancy Complications, Infectious; Quinazolines; Randomized Controlled Trials as Topic; Ribonucleosides	2014
Recent advances in cytomegalovirus: an update on pharmacologic and cellular therapies. Biology of blood and marrow transplantation : journal of the American Society for Blood and Marrow Transplantation, 2015, Volume: 21, Issue:1 Topics: Acetates; Adoptive Transfer; Animals; Antiviral Agents; Benzimidazoles; Cell- and Tissue-Based Therapy; Clinical Trials, Phase III as Topic; Cytomegalovirus; Cytomegalovirus Infections; Cytosine; Hematopoietic Stem Cell Transplantation; Humans; Isoxazoles; Killer Cells, Natural; Leflunomide; Mice; Organophosphonates; Quinazolines; Ribonucleosides; T-Lymphocytes	2015
Current status of chemically synthesized inhibitors of Ebola virus. Recent patents on anti-infective drug discovery, 2014, Volume: 9, Issue:2 Topics: Adenine; Adenosine; Amides; Antiviral Agents; Cytosine; Drug Discovery; Ebolavirus; Hemorrhagic Fever, Ebola; Humans; Organophosphonates; Patents as Topic; Purine Nucleosides; Pyrazines; Pyrrolidines	2014
Addressing Therapeutic Options for Ebola Virus Infection in Current and Future Outbreaks. Antimicrobial agents and chemotherapy, 2015, Volume: 59, Issue:10 Topics: Amides; Amidines; Androstenes; Animals; Anti-Inflammatory Agents; Antibodies, Monoclonal; Antiviral Agents; Benzofurans; Cytosine; Disease Models, Animal; Disease Outbreaks; Ebolavirus; Hemorrhagic Fever, Ebola; Humans; Immune Sera; Organophosphonates; Pyrazines; RNA, Small Interfering; Stilbenes; Virus Replication	2015
Herpes simplex virus and varicella zoster virus: recent advances in therapy. Current opinion in infectious diseases, 2015, Volume: 28, Issue:6 Topics: Antiviral Agents; Clinical Trials as Topic; Cytosine; Drug Discovery; Drug Evaluation; Drug Resistance, Viral; Herpes Simplex; Herpes Zoster; Humans; Microbial Sensitivity Tests; Organophosphonates; Treatment Outcome; Virus Replication	2015
Strategies to prevent BK virus infection in kidney transplant recipients. Current opinion in infectious diseases, 2016, Volume: 29, Issue:4 Topics: BK Virus; Cytosine; Humans; Immunity, Cellular; Immunity, Humoral; Immunosuppression Therapy; Kidney Transplantation; Organophosphonates; Polyomavirus Infections; Postoperative Complications; Prospective Studies; Quinolones; Transplant Recipients; Tumor Virus Infections	2016
Strategies to control human cytomegalovirus infection in adult hematopoietic stem cell transplant recipients. Immunotherapy, 2016, Volume: 8, Issue:9 Topics: Acetates; Adult; Animals; Antiviral Agents; Asymptomatic Diseases; Benzimidazoles; Clinical Trials as Topic; Cytomegalovirus; Cytomegalovirus Infections; Cytosine; Disease Management; Gastroenteritis; Hematopoietic Stem Cell Transplantation; Humans; Immunotherapy; Monitoring, Immunologic; Organophosphonates; Pneumonia; Postoperative Complications; Quinazolines; Ribonucleosides	2016
Adenovirus. Microbiology spectrum, 2016, Volume: 4, Issue:4 Topics: Adenoviridae Infections; Antiviral Agents; Cidofovir; Cytosine; Diagnostic Tests, Routine; Disease Susceptibility; Drug Monitoring; Humans; Immunocompromised Host; Organophosphonates	2016
The alpha-herpesviridae in dermatology : Varicella zoster virus. Der Hautarzt; Zeitschrift fur Dermatologie, Venerologie, und verwandte Gebiete, 2017, Volume: 68, Issue:Suppl 1 Topics: Adult; Child; Child, Preschool; Cytosine; Herpes Zoster Vaccine; Herpesvirus 3, Human; Humans; Infant; Low-Level Light Therapy; Middle Aged; Organophosphonates; Pyrimidine Nucleosides; Recurrence; Risk Factors; Varicella Zoster Virus Infection; Virulence	2017
Disseminated adenovirus infection after allogeneic stem cell transplant and the potential role of brincidofovir - Case series and 10 year experience of management in an adult transplant cohort. Journal of clinical virology : the official publication of the Pan American Society for Clinical Virology, 2017, Volume: 96 Topics: Adenoviridae Infections; Adult; Antiviral Agents; Cohort Studies; Cytosine; Female; Hematopoietic Stem Cell Transplantation; Humans; Male; Middle Aged; Organophosphonates; Transplantation, Homologous; Treatment Outcome; Young Adult	2017
Maribavir, brincidofovir and letermovir: Efficacy and safety of new antiviral drugs for treating cytomegalovirus infections. Medecine et maladies infectieuses, 2018, Volume: 48, Issue:8 Topics: Acetates; Antiviral Agents; Benzimidazoles; Cytomegalovirus Infections; Cytosine; Ganciclovir; Humans; Organophosphonates; Quinazolines; Ribonucleosides	2018
Adenovirus infection in pediatric transplant recipients: are effective antiviral agents coming our way? Current opinion in organ transplantation, 2018, Volume: 23, Issue:4 Topics: Adenoviridae Infections; Antiviral Agents; Child; Cidofovir; Cytosine; Hematopoietic Stem Cell Transplantation; Humans; Immunocompromised Host; Organ Transplantation; Organophosphonates; Pediatrics; Transplant Recipients	2018
Drug Development against Smallpox: Present and Future. Antimicrobial agents and chemotherapy, 2020, 03-24, Volume: 64, Issue:4 Topics: Animals; Antiviral Agents; Benzamides; Biological Warfare Agents; Biomedical Research; Cytosine; Disease Models, Animal; Drug Discovery; Isoindoles; Organophosphonates; Smallpox; Variola virus	2020
Brincidofovir: understanding its unique profile and potential role against adenovirus and other viral infections. Future microbiology, 2020, Volume: 15 Topics: Adenovirus Infections, Human; Animals; Antiviral Agents; Clinical Trials as Topic; Cytosine; DNA Virus Infections; DNA Viruses; Humans; Immunocompromised Host; Organophosphonates	2020
Benefit-risk assessment for brincidofovir for the treatment of smallpox: U.S. Food and Drug Administration's Evaluation. Antiviral research, 2021, Volume: 195 Topics: Animals; Antiviral Agents; Cytosine; Disease Eradication; Disease Models, Animal; Drug Approval; Humans; Organophosphonates; Risk Assessment; Smallpox; Treatment Outcome; United States; United States Food and Drug Administration	2021
Antivirals With Activity Against Mpox: A Clinically Oriented Review. Clinical infectious diseases : an official publication of the Infectious Diseases Society of America, 2023, 01-06, Volume: 76, Issue:1 Topics: Animals; Antiviral Agents; Cidofovir; Cytosine; Humans; Monkeypox virus; Mpox (monkeypox); Organophosphonates	2023
Brincidofovir: A Novel Agent for the Treatment of Smallpox. The Annals of pharmacotherapy, 2023, Volume: 57, Issue:10 Topics: Animals; Antiviral Agents; Cytomegalovirus; Cytosine; Disease Models, Animal; Hematopoietic Stem Cell Transplantation; Humans; Mice; Rabbits; Smallpox; Variola virus	2023

Trials

5 trial(s) available for cytosine and cmx 001

Article	Year
First pharmacokinetic and safety study in humans of the novel lipid antiviral conjugate CMX001, a broad-spectrum oral drug active against double-stranded DNA viruses. Antimicrobial agents and chemotherapy, 2012, Volume: 56, Issue:5 Topics: Administration, Oral; Adolescent; Adult; Antiviral Agents; Area Under Curve; Biological Availability; Capsule Endoscopy; Cidofovir; Cytosine; DNA Viruses; Double-Blind Method; Drug Administration Schedule; Drug-Related Side Effects and Adverse Reactions; Female; Humans; Intraocular Pressure; Kidney Function Tests; Male; Middle Aged; Organophosphonates; Placebos; United States	2012
CMX001 to prevent cytomegalovirus disease in hematopoietic-cell transplantation. The New England journal of medicine, 2013, Sep-26, Volume: 369, Issue:13 Topics: Administration, Oral; Adult; Antiviral Agents; Cytomegalovirus; Cytomegalovirus Infections; Cytosine; Diarrhea; DNA, Viral; Dose-Response Relationship, Drug; Double-Blind Method; Female; Hematopoietic Stem Cell Transplantation; Humans; Incidence; Male; Organophosphonates; Polymerase Chain Reaction; Transplantation, Homologous	2013
Experimental Treatment of Ebola Virus Disease with Brincidofovir. PloS one, 2016, Volume: 11, Issue:9 Topics: Adult; Antiviral Agents; Cytosine; Ebolavirus; Female; Hemorrhagic Fever, Ebola; Humans; Liberia; Male; Middle Aged; Organophosphonates; Treatment Outcome; Young Adult	2016
Short-term clinical safety profile of brincidofovir: A favorable benefit-risk proposition in the treatment of smallpox. Antiviral research, 2017, Volume: 143 Topics: Adenoviridae; Adolescent; Adult; Animals; Antiviral Agents; Cytomegalovirus; Cytosine; Disease Models, Animal; Double-Blind Method; Drug Administration Schedule; Humans; Middle Aged; Organophosphonates; Orthopoxvirus; Safety; Smallpox; Young Adult	2017
A Randomized, Double-Blind, Placebo-Controlled Phase 3 Trial of Oral Brincidofovir for Cytomegalovirus Prophylaxis in Allogeneic Hematopoietic Cell Transplantation. Biology of blood and marrow transplantation : journal of the American Society for Blood and Marrow Transplantation, 2019, Volume: 25, Issue:2 Topics: Administration, Oral; Adolescent; Adult; Aged; Allografts; Cytomegalovirus; Cytomegalovirus Infections; Cytosine; Disease-Free Survival; Female; Hematopoietic Stem Cell Transplantation; Humans; Male; Middle Aged; Organophosphonates; Survival Rate	2019

Other Studies

77 other study(ies) available for cytosine and cmx 001

Article	Year
Synergistic efficacy of the combination of ST-246 with CMX001 against orthopoxviruses. Antimicrobial agents and chemotherapy, 2007, Volume: 51, Issue:11 Topics: Administration, Oral; Animals; Antiviral Agents; Benzamides; Cells, Cultured; Chlorocebus aethiops; Cowpox virus; Cytosine; Dose-Response Relationship, Drug; Drug Synergism; Drug Therapy, Combination; Female; Humans; Isoindoles; Male; Mice; Mice, Inbred BALB C; Organophosphonates; Orthopoxvirus; Poxviridae Infections; Treatment Outcome; Vaccinia virus; Vero Cells; Virus Replication	2007
Efficacy of therapeutic intervention with an oral ether-lipid analogue of cidofovir (CMX001) in a lethal mousepox model. Antiviral research, 2008, Volume: 77, Issue:1 Topics: Administration, Oral; Animals; Antiviral Agents; Cidofovir; Cytosine; Ectromelia virus; Ectromelia, Infectious; Ether; Female; Hepatocytes; Humans; Mice; Mice, Inbred A; Organophosphonates	2008
Hexadecyloxypropyl-cidofovir, CMX001, prevents adenovirus-induced mortality in a permissive, immunosuppressed animal model. Proceedings of the National Academy of Sciences of the United States of America, 2008, May-20, Volume: 105, Issue:20 Topics: Adenoviridae; Adenoviridae Infections; Animals; Antiviral Agents; Cricetinae; Cytosine; Disease Models, Animal; Drug Screening Assays, Antitumor; Hematopoietic Stem Cells; Humans; Immunosuppressive Agents; Liver; Mesocricetus; Models, Biological; Organophosphonates	2008
Using biomarkers to stage disease progression in a lethal mousepox model treated with CMX001. Antiviral therapy, 2008, Volume: 13, Issue:7 Topics: Alanine Transaminase; Animals; Antiviral Agents; Aspartate Aminotransferases; Biomarkers; Cell Line; Cytosine; Disease Models, Animal; Disease Progression; DNA, Viral; Ectromelia virus; Ectromelia, Infectious; Female; Humans; Interferon-gamma; Mice; Organophosphonates; Treatment Outcome; Weight Loss	2008
Mousepox in the C57BL/6 strain provides an improved model for evaluating anti-poxvirus therapies. Virology, 2009, Mar-01, Volume: 385, Issue:1 Topics: Animals; Antiviral Agents; Cell Line; Chlorocebus aethiops; Cytokines; Cytosine; Disease Models, Animal; Ectromelia virus; Ectromelia, Infectious; Female; Mice; Mice, Inbred C57BL; Organophosphonates	2009
A mouse model of lethal infection for evaluating prophylactics and therapeutics against Monkeypox virus. Journal of virology, 2010, Volume: 84, Issue:8 Topics: Animals; Antiviral Agents; Benzamides; Cytosine; Disease Models, Animal; Female; Humans; Isoindoles; Liver; Lung; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; Monkeypox virus; Mpox (monkeypox); Organophosphonates; Smallpox Vaccine; Spleen; STAT1 Transcription Factor; Survival Analysis; Treatment Outcome; Vaccinia virus; Viral Load	2010
1-O-hexadecyloxypropyl cidofovir (CMX001) effectively inhibits polyomavirus BK replication in primary human renal tubular epithelial cells. Antimicrobial agents and chemotherapy, 2010, Volume: 54, Issue:11 Topics: Antiviral Agents; BK Virus; Blotting, Western; Cell Proliferation; Cell Survival; Cells, Cultured; Cytosine; Humans; Microscopy, Fluorescence; Organophosphonates; Reverse Transcriptase Polymerase Chain Reaction; Virus Replication	2010
Hexadecyloxypropyl-cidofovir (CMX001) suppresses JC virus replication in human fetal brain SVG cell cultures. Antimicrobial agents and chemotherapy, 2010, Volume: 54, Issue:11 Topics: Antiviral Agents; Brain; Cell Line; Cytosine; Fetus; Humans; In Situ Hybridization; JC Virus; Microscopy, Phase-Contrast; Molecular Structure; Organophosphonates; Polymerase Chain Reaction; Virus Replication	2010
A case of progressive multifocal leukoencephalopathy and idiopathic CD4+ lymphocytopenia. The Journal of antimicrobial chemotherapy, 2010, Volume: 65, Issue:12 Topics: Antiviral Agents; CD4 Lymphocyte Count; Cytosine; Humans; Interleukin-7; JC Virus; Leukoencephalopathy, Progressive Multifocal; Magnetic Resonance Imaging; Organophosphonates; T-Lymphocytopenia, Idiopathic CD4-Positive; Viral Load	2010
Efficacy of CMX001 against herpes simplex virus infections in mice and correlations with drug distribution studies. The Journal of infectious diseases, 2010, Nov-15, Volume: 202, Issue:10 Topics: Administration, Oral; Animals; Antiviral Agents; Cytosine; Disease Models, Animal; Drug Evaluation, Preclinical; Female; Herpes Simplex; Herpesvirus 1, Human; Herpesvirus 2, Human; Mice; Mice, Inbred BALB C; Organophosphonates; Tissue Distribution	2010
Poxvirus interleukin-4 expression overcomes inherent resistance and vaccine-induced immunity: pathogenesis, prophylaxis, and antiviral therapy. Virology, 2011, Jan-20, Volume: 409, Issue:2 Topics: Animals; Antiviral Agents; Benzamides; Cytosine; Ectromelia virus; Ectromelia, Infectious; Female; Gene Expression Regulation; Interleukin-4; Isoindoles; Mice; Mice, Inbred C57BL; Organophosphonates; Promoter Regions, Genetic; Recombinant Proteins; Survival Analysis; Treatment Outcome	2011
Oral hexadecyloxypropyl-cidofovir therapy in pregnant guinea pigs improves outcome in the congenital model of cytomegalovirus infection. Antimicrobial agents and chemotherapy, 2011, Volume: 55, Issue:1 Topics: Administration, Oral; Animals; Antiviral Agents; Cytomegalovirus Infections; Cytosine; Disease Models, Animal; Female; Guinea Pigs; Organophosphonates; Pregnancy; Treatment Outcome	2011
Eradication of disseminated adenovirus infection in a pediatric hematopoietic stem cell transplantation recipient using the novel antiviral agent CMX001. Journal of clinical virology : the official publication of the Pan American Society for Clinical Virology, 2011, Volume: 50, Issue:2 Topics: Adenovirus Infections, Human; Antiviral Agents; Child; Cytosine; Female; Hematopoietic Stem Cell Transplantation; Humans; Immunocompromised Host; Organophosphonates; Polymerase Chain Reaction	2011
CMX001 (1-O-hexadecyloxypropyl-cidofovir) inhibits polyomavirus JC replication in human brain progenitor-derived astrocytes. Antimicrobial agents and chemotherapy, 2011, Volume: 55, Issue:5 Topics: Animals; Astrocytes; Brain; Cells, Cultured; Chlorocebus aethiops; COS Cells; Cytosine; Fluorescent Antibody Technique; Humans; JC Virus; Organophosphonates; Polymerase Chain Reaction; Stem Cells; Virus Replication	2011
CMX001 potentiates the efficacy of acyclovir in herpes simplex virus infections. Antimicrobial agents and chemotherapy, 2011, Volume: 55, Issue:10 Topics: Acyclovir; Animals; Antiviral Agents; Cells, Cultured; Cytosine; Drug Resistance, Viral; Drug Synergism; Drug Therapy, Combination; Female; Herpes Simplex; Herpesvirus 1, Human; Herpesvirus 2, Human; Humans; Mice; Mice, Inbred BALB C; Organophosphonates	2011
Biodefence since 9/11: The price of protection. Nature, 2011, Sep-07, Volume: 477, Issue:7363 Topics: Animals; Antiviral Agents; Biomedical Research; Bioterrorism; Budgets; Cytosine; Disease Models, Animal; Humans; Male; Organophosphonates; Security Measures; September 11 Terrorist Attacks; Smallpox; Tularemia; United States; Vaccines; Young Adult	2011
Safety and efficacy of CMX001 as salvage therapy for severe adenovirus infections in immunocompromised patients. Biology of blood and marrow transplantation : journal of the American Society for Blood and Marrow Transplantation, 2012, Volume: 18, Issue:5 Topics: Adenoviridae; Adenoviridae Infections; Adolescent; Adult; Aged; Antiviral Agents; Child; Child, Preschool; Cytosine; Female; Humans; Immunocompromised Host; Infant; Male; Middle Aged; Organophosphonates; Retrospective Studies; Salvage Therapy; Severity of Illness Index; Stem Cell Transplantation; Transplantation, Homologous; Treatment Outcome; Viral Load	2012
Scientific report: highlights of 24th ICAR, 8-11 May 2011, Sofia, Bulgaria. Antiviral chemistry & chemotherapy, 2011, Oct-07, Volume: 22, Issue:2 Topics: Adenine; Animals; Antiviral Agents; Arenavirus; Chemistry, Pharmaceutical; Communicable Diseases, Emerging; Cytosine; Flavivirus; Hepacivirus; HIV Seropositivity; Humans; Organophosphonates; Prodrugs; Smallpox; Tenofovir; Virus Replication	2011
Intraocular safety and pharmacokinetics of hexadecyloxypropyl-cidofovir (HDP-CDV) as a long-lasting intravitreal antiviral drug. Investigative ophthalmology & visual science, 2011, Dec-09, Volume: 52, Issue:13 Topics: Animals; Chromatography, High Pressure Liquid; Ciliary Body; Cytomegalovirus Retinitis; Cytosine; Delayed-Action Preparations; Disease Models, Animal; Dose-Response Relationship, Drug; Follow-Up Studies; Hydrolysis; Intravitreal Injections; Organophosphonates; Rabbits; Retina; Vitreous Body	2011
Detection of molluscum contagiosum virus (MCV) DNA in the plasma of an immunocompromised patient and possible reduction of MCV DNA with CMX-001. The Journal of infectious diseases, 2012, Mar-01, Volume: 205, Issue:5 Topics: Adult; Antiviral Agents; Compassionate Use Trials; Cytosine; DNA, Viral; Female; Humans; Immunologic Deficiency Syndromes; Molluscum Contagiosum; Molluscum contagiosum virus; Organophosphonates; Real-Time Polymerase Chain Reaction; Young Adult	2012
Evaluation of disease and viral biomarkers as triggers for therapeutic intervention in respiratory mousepox - an animal model of smallpox. Antiviral research, 2012, Volume: 94, Issue:1 Topics: Animals; Benzamides; Biomarkers, Pharmacological; Cell Line; Cytosine; Disease Models, Animal; Drug Evaluation, Preclinical; Ectromelia virus; Ectromelia, Infectious; Female; Humans; Isoindoles; Mice; Mice, Hairless; Mice, Inbred C57BL; Monkeypox virus; Organophosphonates; Smallpox; Variola virus; Virus Replication	2012
Progressive vaccinia: case description and laboratory-guided therapy with vaccinia immune globulin, ST-246, and CMX001. The Journal of infectious diseases, 2012, Volume: 206, Issue:9 Topics: Adult; Antibodies, Viral; Antiviral Agents; Benzamides; Cytosine; Drug Resistance, Viral; Humans; Immunoglobulins; Isoindoles; Male; Organophosphonates; Smallpox Vaccine; Treatment Outcome; Vaccinia; Vaccinia virus	2012
HDP-CDV as an alternative for treatment of human herpesvirus-6 infections. Journal of clinical virology : the official publication of the Pan American Society for Clinical Virology, 2013, Volume: 56, Issue:2 Topics: Antiviral Agents; Cell Line; Cytosine; Herpesvirus 6, Human; Humans; Microbial Sensitivity Tests; Organophosphonates; Roseolovirus Infections	2013
Fatal adenovirus encephalomyeloradiculitis in an umbilical cord stem cell transplant recipient. Neurology, 2013, Apr-30, Volume: 80, Issue:18 Topics: Adenoviridae Infections; Antiviral Agents; Cidofovir; Cord Blood Stem Cell Transplantation; Cytosine; Encephalomyelitis; Fatal Outcome; Female; Humans; Leukemia, Prolymphocytic, T-Cell; Middle Aged; Organophosphonates	2013
Selection and recombinant phenotyping of a novel CMX001 and cidofovir resistance mutation in human cytomegalovirus. Antimicrobial agents and chemotherapy, 2013, Volume: 57, Issue:7 Topics: Amino Acid Sequence; Antiviral Agents; Base Sequence; Cells, Cultured; Chromosomes, Artificial, Bacterial; Cidofovir; Cytomegalovirus; Cytomegalovirus Infections; Cytosine; DNA-Directed DNA Polymerase; Drug Resistance, Viral; Foscarnet; Ganciclovir; Humans; Mutation; Organophosphonates; Phenotype; Sequence Analysis, DNA	2013
In vitro efficacy of brincidofovir against variola virus. Antimicrobial agents and chemotherapy, 2014, Volume: 58, Issue:9 Topics: Animals; Antiviral Agents; Cell Line; Chlorocebus aethiops; Cidofovir; Cytosine; Disease Models, Animal; DNA, Viral; Humans; In Vitro Techniques; Microbial Sensitivity Tests; Organophosphonates; Smallpox; Variola virus	2014
Development of CMX001 (Brincidofovir) for the treatment of serious diseases or conditions caused by dsDNA viruses. Expert review of anti-infective therapy, 2014, Volume: 12, Issue:10 Topics: Adenoviridae; Antiviral Agents; Cytomegalovirus; Cytosine; DNA Virus Infections; Humans; Microbial Sensitivity Tests; Molluscum contagiosum virus; Organophosphonates; Orthopoxvirus; Polyomavirus	2014
Co-administration of the broad-spectrum antiviral, brincidofovir (CMX001), with smallpox vaccine does not compromise vaccine protection in mice challenged with ectromelia virus. Antiviral research, 2014, Volume: 111 Topics: Animals; Antiviral Agents; Cytosine; Ectromelia virus; Ectromelia, Infectious; Female; Humans; Immunity; Mice; Mice, Inbred C57BL; Organophosphonates; Smallpox Vaccine; Vaccination; Virus Replication	2014
Treatment of BK virus-associated nephropathy with CMX001 after kidney transplantation in a young child. Pediatric transplantation, 2014, Volume: 18, Issue:7 Topics: Administration, Oral; Biopsy; BK Virus; Child, Preschool; Ciprofloxacin; Creatinine; Cytosine; DNA, Viral; Female; Humans; Immunosuppressive Agents; Isoxazoles; Kidney Transplantation; Leflunomide; Organophosphonates; Renal Insufficiency; Renal Insufficiency, Chronic; Viral Load	2014
Ganciclovir inhibits human adenovirus replication and pathogenicity in permissive immunosuppressed Syrian hamsters. Antimicrobial agents and chemotherapy, 2014, Volume: 58, Issue:12 Topics: Adenoviridae Infections; Adenoviruses, Human; Animals; Antiviral Agents; Body Weight; Cell Line, Tumor; Cytosine; DNA-Directed DNA Polymerase; Female; Ganciclovir; Gene Expression; Humans; Immunocompromised Host; Male; Mesocricetus; Organophosphonates; Survival Analysis; Transaminases; Viral Load; Viral Proteins; Virus Replication	2014
A dose of reality. Science (New York, N.Y.), 2014, Nov-21, Volume: 346, Issue:6212 Topics: Antibodies, Viral; Antiviral Agents; Cytosine; Ebolavirus; Hemorrhagic Fever, Ebola; Humans; Organophosphonates; Randomized Controlled Trials as Topic; Serum; Therapies, Investigational	2014
Cidofovir and brincidofovir reduce the pathology caused by systemic infection with human type 5 adenovirus in immunosuppressed Syrian hamsters, while ribavirin is largely ineffective in this model. Antiviral research, 2014, Volume: 112 Topics: Adenoviridae Infections; Adenoviruses, Human; Alanine Transaminase; Animals; Body Weight; Cell Line; Cidofovir; Cytosine; Disease Models, Animal; Female; Humans; Immunocompromised Host; Liver; Mesocricetus; Organophosphonates; Ribavirin; Survival Analysis; Treatment Outcome; Viral Load	2014
Micelle formulation of hexadecyloxypropyl-cidofovir (HDP-CDV) as an intravitreal long-lasting delivery system. European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft fur Pharmazeutische Verfahrenstechnik e.V, 2015, Volume: 89 Topics: Animals; Antiviral Agents; Chemistry, Pharmaceutical; Cytosine; Delayed-Action Preparations; Drug Delivery Systems; Guinea Pigs; Half-Life; Herpes Simplex; Herpesvirus 1, Human; Intravitreal Injections; Micelles; Organophosphonates; Prodrugs; Rabbits; Retina; Vitreous Body	2015
[Ebola: three experimental clinical trials directed by MSF]. Revue medicale suisse, 2014, Nov-26, Volume: 10, Issue:452 Topics: Africa, Western; Amides; Anti-Infective Agents; Clinical Trials as Topic; Cytosine; France; Health Services Accessibility; Hemorrhagic Fever, Ebola; Humans; International Cooperation; Organophosphonates; Pyrazines; Societies, Medical	2014
Postchallenge administration of brincidofovir protects healthy and immune-deficient mice reconstituted with limited numbers of T cells from lethal challenge with IHD-J-Luc vaccinia virus. Journal of virology, 2015, Volume: 89, Issue:6 Topics: Animals; Antiviral Agents; Cytosine; Female; Humans; Luciferases; Lymphocyte Count; Mice; Mice, Inbred BALB C; Mice, Nude; Organophosphonates; Protective Agents; T-Lymphocytes; Vaccinia; Vaccinia virus; Viral Load	2015
Brincidofovir for polyomavirus-associated nephropathy after allogeneic hematopoietic stem cell transplantation. American journal of kidney diseases : the official journal of the National Kidney Foundation, 2015, Volume: 65, Issue:5 Topics: BK Virus; Cytomegalovirus Infections; Cytosine; Hematopoietic Stem Cell Transplantation; Humans; Immunocompromised Host; Kidney Diseases; Male; Middle Aged; Organophosphonates; Polyomavirus; Polyomavirus Infections; Tumor Virus Infections; Viremia	2015
Infectious diseases. Ebola drug trials lurch ahead. Science (New York, N.Y.), 2015, Feb-13, Volume: 347, Issue:6223 Topics: Amides; Antibodies, Monoclonal; Antiviral Agents; Clinical Trials as Topic; Cytosine; Disease Outbreaks; Ebolavirus; Hemorrhagic Fever, Ebola; Humans; Organophosphonates; Pyrazines	2015
The efficacy and pharmacokinetics of brincidofovir for the treatment of lethal rabbitpox virus infection: a model of smallpox disease. Antiviral research, 2015, Volume: 117 Topics: Animals; Antibodies, Neutralizing; Antibodies, Viral; Antiviral Agents; Cidofovir; Cytosine; Disease Models, Animal; Humans; Injections, Intradermal; Organophosphonates; Rabbits; Random Allocation; Smallpox; Vaccinia; Vaccinia virus; Variola virus	2015
Brincidofovir (CMX001) inhibits BK polyomavirus replication in primary human urothelial cells. Antimicrobial agents and chemotherapy, 2015, Volume: 59, Issue:6 Topics: Antiviral Agents; BK Virus; Blotting, Western; Cell Survival; Cells, Cultured; Cytosine; Humans; Organophosphonates; Virus Replication	2015
Infectious disease. Combating emerging viral threats. Science (New York, N.Y.), 2015, Apr-17, Volume: 348, Issue:6232 Topics: Adenine; Adenosine; Antiviral Agents; Benzamides; Chloroquine; Communicable Diseases, Emerging; Cyclosporins; Cytosine; Dengue; Drug Approval; Drug Design; Erlotinib Hydrochloride; Hemorrhagic Fever, Ebola; Humans; Imatinib Mesylate; Indoles; Organophosphonates; Piperazines; Purine Nucleosides; Pyrimidines; Pyrroles; Pyrrolidines; Quinazolines; Sunitinib; Viruses	2015
Administration of Brincidofovir and Convalescent Plasma in a Patient With Ebola Virus Disease. Clinical infectious diseases : an official publication of the Infectious Diseases Society of America, 2015, Sep-15, Volume: 61, Issue:6 Topics: Adult; Africa, Western; Alanine Transaminase; Antibodies, Viral; Antiviral Agents; Aspartate Aminotransferases; Bilirubin; Cytosine; Hemorrhagic Fever, Ebola; Humans; Immunization, Passive; Immunoglobulin G; Immunoglobulin M; Leukocyte Count; Male; Organophosphonates; Plasma; Platelet Count; Randomized Controlled Trials as Topic; RNA, Viral; Treatment Outcome; Viral Load	2015
Ebola: Embed research in outbreak response. Nature, 2015, Aug-06, Volume: 524, Issue:7563 Topics: Adult; Biomedical Research; Child; Clinical Trials as Topic; Cooperative Behavior; Cytosine; Disaster Planning; Disease Outbreaks; Hemorrhagic Fever, Ebola; Humans; Information Dissemination; Liberia; Organophosphonates; Time Factors; Treatment Outcome; World Health Organization	2015
New drug on the horizon for treating adenovirus. Expert opinion on pharmacotherapy, 2015, Volume: 16, Issue:14 Topics: Adenoviridae Infections; Adenoviruses, Human; Adoptive Transfer; Animals; Antiviral Agents; Cidofovir; Cytosine; DNA, Viral; Humans; Immunocompromised Host; Organophosphonates; T-Lymphocytes	2015
The lipid moiety of brincidofovir is required for in vitro antiviral activity against Ebola virus. Antiviral research, 2016, Volume: 125 Topics: Animals; Antiviral Agents; Cell Line, Tumor; Chlorocebus aethiops; Cidofovir; Cytosine; Drug Evaluation, Preclinical; Ebolavirus; HeLa Cells; Hemorrhagic Fever, Ebola; Human Umbilical Vein Endothelial Cells; Humans; Lipids; Male; Organophosphonates; Structure-Activity Relationship; Vero Cells; Virus Replication	2016
INFECTIOUS DISEASE. As Ebola epidemic draws to a close, a thin scientific harvest. Science (New York, N.Y.), 2016, Jan-01, Volume: 351, Issue:6268 Topics: Africa, Western; Antiviral Agents; Clinical Trials as Topic; Cytosine; Ebola Vaccines; Ebolavirus; Epidemics; Global Health; Hemorrhagic Fever, Ebola; Humans; Organophosphonates; World Health Organization	2016
Trial design for evaluating novel treatments during an outbreak of an infectious disease. Clinical trials (London, England), 2016, Volume: 13, Issue:1 Topics: Antiviral Agents; Clinical Protocols; Clinical Trials, Phase II as Topic; Clinical Trials, Phase III as Topic; Cytosine; Disease Outbreaks; Hemorrhagic Fever, Ebola; Humans; Liberia; Organophosphonates; Randomized Controlled Trials as Topic; Research Design; Sierra Leone; Survival Rate; Treatment Outcome	2016
Novel Cytomegalovirus UL54 DNA Polymerase Gene Mutations Selected In Vitro That Confer Brincidofovir Resistance. Antimicrobial agents and chemotherapy, 2016, Volume: 60, Issue:6 Topics: Antiviral Agents; Cidofovir; Cytomegalovirus; Cytomegalovirus Infections; Cytosine; DNA-Directed DNA Polymerase; Drug Resistance, Viral; Foscarnet; Ganciclovir; Gene Expression; Humans; Microbial Sensitivity Tests; Mutation; Organophosphonates; Protein Domains; Viral Proteins	2016
Fairer way to distribute last-ditch drugs gets real-world trial. Nature, 2016, 06-09, Volume: 534, Issue:7606 Topics: Antibodies, Monoclonal; Child; Compassionate Use Trials; Controlled Clinical Trials as Topic; Cytosine; Drug Approval; Drug Industry; Humans; Male; Multiple Myeloma; Organophosphonates; Patient Advocacy; Patient Selection; Social Media; United States; United States Food and Drug Administration	2016
Brincidofovir treatment of acyclovir-resistant disseminated varicella zoster virus infection in an immunocompromised host. Transplant infectious disease : an official journal of the Transplantation Society, 2016, Volume: 18, Issue:5 Topics: Acyclovir; Adult; Antibiotic Prophylaxis; Antineoplastic Agents; Antiviral Agents; Cytosine; Drug Resistance, Viral; Drugs, Investigational; Female; Foscarnet; Graft vs Host Disease; Hematopoietic Stem Cell Transplantation; Herpes Zoster; Herpesvirus 3, Human; Humans; Immunocompromised Host; Investigational New Drug Application; Leukemia, Myelogenous, Chronic, BCR-ABL Positive; Organophosphonates; Transplantation, Homologous; Valacyclovir; Valine	2016
Brincidofovir clearance of acyclovir-resistant herpes simplex virus-1 and adenovirus infection after stem cell transplantation. Transplant infectious disease : an official journal of the Transplantation Society, 2016, Volume: 18, Issue:5 Topics: Acyclovir; Adenoviridae; Adenovirus Infections, Human; Antibiotic Prophylaxis; Antiviral Agents; Child, Preschool; Cidofovir; Cytosine; DNA, Viral; Drug Resistance, Viral; Epstein-Barr Virus Infections; Female; Foscarnet; Hematopoietic Stem Cell Transplantation; Herpes Simplex; Herpes Zoster; Herpesvirus 1, Human; Herpesvirus 3, Human; Herpesvirus 4, Human; Humans; Immunocompromised Host; Meningoencephalitis; Mucositis; Myelodysplastic Syndromes; Organophosphonates; Rituximab; Viral Load	2016
The use of brincidofovir for the treatment of mixed dsDNA viral infection. Journal of clinical virology : the official publication of the Pan American Society for Clinical Virology, 2016, Volume: 83 Topics: Adult; Antiviral Agents; BK Virus; Coinfection; Cytomegalovirus; Cytosine; DNA Virus Infections; Fatal Outcome; Female; Herpesvirus 4, Human; Humans; Immunocompromised Host; Organophosphonates; Stem Cell Transplantation; Viral Load; Young Adult	2016
Brincidofovir (CMX-001) for refractory and resistant CMV and HSV infections in immunocompromised cancer patients: A single-center experience. Antiviral research, 2016, Volume: 134 Topics: Aged; Antiviral Agents; Clinical Trials as Topic; Cytomegalovirus; Cytomegalovirus Infections; Cytosine; Drug Resistance, Viral; Female; Hematopoietic Stem Cell Transplantation; Herpes Simplex; Herpesviridae Infections; Humans; Immunocompromised Host; Male; Middle Aged; Neoplasms; Organophosphonates	2016
Brincidofovir Is Not a Substrate for the Human Organic Anion Transporter 1: A Mechanistic Explanation for the Lack of Nephrotoxicity Observed in Clinical Studies. Therapeutic drug monitoring, 2016, Volume: 38, Issue:6 Topics: Adolescent; Adult; Aged; Animals; Antiviral Agents; Biological Transport; Cell Line; Child; Cytosine; Dogs; Female; Glomerular Filtration Rate; Humans; Kidney Tubules, Proximal; Madin Darby Canine Kidney Cells; Male; Middle Aged; Organic Anion Transport Protein 1; Organophosphonates; Young Adult	2016
Case report: Brincidofovir-induced reversible severe acute kidney injury in 2 solid-organ transplant for treatment of cytomegalovirus infection. Medicine, 2016, Volume: 95, Issue:44 Topics: Acute Kidney Injury; Antiviral Agents; Cytomegalovirus Infections; Cytosine; Heart Transplantation; Humans; Kidney Transplantation; Male; Middle Aged; Organophosphonates; Postoperative Complications; Severity of Illness Index	2016
Buccal viral DNA as a trigger for brincidofovir therapy in the mousepox model of smallpox. Antiviral research, 2017, Volume: 139 Topics: Animals; Antiviral Agents; Cytosine; Disease Models, Animal; DNA, Viral; Ectromelia virus; Ectromelia, Infectious; Mice; Mouth Mucosa; Organophosphonates; Orthopoxvirus; Smallpox	2017
Efficacy of delayed brincidofovir treatment against a lethal rabbitpox virus challenge in New Zealand White rabbits. Antiviral research, 2017, Volume: 143 Topics: Animals; Antibodies, Neutralizing; Antibodies, Viral; Antiviral Agents; Body Temperature; Body Weight; Cytosine; Disease Models, Animal; Double-Blind Method; Organophosphonates; Poxviridae Infections; Rabbits; Smallpox; Survival Rate; Treatment Outcome; Vaccination; Vaccinia; Vaccinia virus; Variola virus; Viral Load	2017
Combination therapy with brincidofovir and valganciclovir against species C adenovirus infection in the immunosuppressed Syrian hamster model allows for substantial reduction of dose for both compounds. Antiviral research, 2017, Volume: 146 Topics: Adenoviridae Infections; Adenoviruses, Human; Animals; Antiviral Agents; Cytosine; Disease Models, Animal; Drug Therapy, Combination; Ganciclovir; HEK293 Cells; Humans; Immunocompromised Host; Mesocricetus; Organophosphonates; Valganciclovir; Viral Load; Virus Replication	2017
Brincidofovir as Salvage Therapy for Adenovirus Disease in Intestinal Transplant Recipients. Pharmacotherapy, 2018, Volume: 38, Issue:4 Topics: Adenoviridae Infections; Adult; Antiviral Agents; Cytosine; Female; Humans; Immunocompromised Host; Male; Organophosphonates; Salvage Therapy; Transplant Recipients	2018
Successful Brincidofovir Treatment of Metagenomics-detected Adenovirus Infection in a Severely Ill Signal Transducer and Activator of Transcription-1-deficient Patient. The Pediatric infectious disease journal, 2019, Volume: 38, Issue:3 Topics: Adenoviridae Infections; Antiviral Agents; Cytosine; Humans; Immunocompromised Host; Liver; Male; Metagenomics; Organophosphonates; Osteomyelitis; STAT1 Transcription Factor; Treatment Outcome; Young Adult	2019
The Role of Brincidofovir in Preparation for a Potential Smallpox Outbreak. Viruses, 2017, 10-30, Volume: 9, Issue:11 Topics: Animals; Antiviral Agents; Benzamides; Biological Warfare Agents; Cytosine; Databases, Pharmaceutical; Disease Outbreaks; Drug Resistance, Viral; Drug Therapy, Combination; Humans; Isoindoles; Models, Animal; Organophosphonates; Smallpox; Variola virus	2017
Brincidofovir (CMX001) Toxicity Associated With Epithelial Apoptosis and Crypt Drop Out in a Hematopoietic Cell Transplant Patient: Challenges in Distinguishing Drug Toxicity From GVHD. Journal of pediatric hematology/oncology, 2018, Volume: 40, Issue:6 Topics: Adenoviridae; Adenoviridae Infections; Autografts; Child, Preschool; Colon; Cytosine; Graft vs Host Disease; Hematopoietic Stem Cell Transplantation; Humans; Male; Medulloblastoma; Octreotide; Organophosphonates; Viremia	2018
The spectre of smallpox lingers. Nature, 2018, Volume: 560, Issue:7718 Topics: Animals; Benzamides; Cytosine; Disease Eradication; Disease Models, Animal; Disease Reservoirs; Drug Approval; Female; History, 20th Century; History, 21st Century; Humans; Isoindoles; Organophosphonates; Rabbits; Smallpox; Smallpox Vaccine; Synthetic Biology; United States; United States Food and Drug Administration	2018
Efficacy of brincidofovir as prophylaxis against HSV and VZV in hematopoietic cell transplant recipients. Transplant infectious disease : an official journal of the Transplantation Society, 2018, Volume: 20, Issue:6 Topics: Adult; Aged; Antibiotic Prophylaxis; Child; Child, Preschool; Cytosine; Female; Hematopoietic Stem Cell Transplantation; Herpes Simplex; Herpesvirus 3, Human; Humans; Infant; Male; Middle Aged; Organophosphonates; Retrospective Studies; Simplexvirus; Treatment Outcome; Varicella Zoster Virus Infection; Young Adult	2018
In vitro evaluation of current and novel antivirals in combination against human cytomegalovirus. Antiviral research, 2018, Volume: 158 Topics: Antiviral Agents; Benzimidazoles; Cell Line; Cidofovir; Cyclopropanes; Cytomegalovirus; Cytomegalovirus Infections; Cytosine; DNA-Directed DNA Polymerase; Drug Antagonism; Drug Combinations; Drug Resistance, Viral; Drug Synergism; Drug Therapy, Combination; Endodeoxyribonucleases; Fibroblasts; Foscarnet; Ganciclovir; Guanine; Humans; Nucleic Acid Synthesis Inhibitors; Organophosphonates; Ribonucleosides; Viral Proteins; Virus Replication	2018
Cidofovir Diphosphate Inhibits Adenovirus 5 DNA Polymerase via both Nonobligate Chain Termination and Direct Inhibition, and Polymerase Mutations Confer Cidofovir Resistance on Intact Virus. Antimicrobial agents and chemotherapy, 2019, Volume: 63, Issue:1 Topics: Adenovirus Infections, Human; Adenoviruses, Human; Antiviral Agents; Cidofovir; Cytosine; DNA Primers; DNA-Directed DNA Polymerase; DNA, Viral; Dose-Response Relationship, Drug; Humans; Kinetics; Mutation; Organophosphonates; Real-Time Polymerase Chain Reaction; Recombinant Proteins; Viral Proteins; Virus Replication	2019
Brincidofovir as a Salvage Therapy in Controlling Adenoviremia in Pediatric Recipients of Hematopoietic Stem Cell Transplant. Journal of pediatric hematology/oncology, 2019, Volume: 41, Issue:7 Topics: Adenovirus Infections, Human; Adolescent; Antiviral Agents; Child; Child, Preschool; Cytosine; Female; Hematopoietic Stem Cell Transplantation; Humans; Immunocompromised Host; Infant; Male; Organophosphonates; Salvage Therapy; Viremia	2019
Artemisone demonstrates synergistic antiviral activity in combination with approved and experimental drugs active against human cytomegalovirus. Antiviral research, 2019, Volume: 172 Topics: Acetates; Antiviral Agents; Artemisinins; Benzimidazoles; Cidofovir; Cytomegalovirus; Cytomegalovirus Infections; Cytosine; Drug Interactions; Drug Synergism; Drugs, Investigational; Female; Ganciclovir; Humans; Organ Culture Techniques; Organophosphonates; Placenta; Pregnancy; Quinazolines; Ribonucleosides	2019
Failure of antiviral therapy with brincidofovir in non-HIV progressive multifocal leukoencephalopathy. Acta neurologica Belgica, 2020, Volume: 120, Issue:5 Topics: Antiviral Agents; Cytosine; Fatal Outcome; Female; Humans; Leukoencephalopathy, Progressive Multifocal; Male; Middle Aged; Organophosphonates; Treatment Failure	2020
Oral brincidofovir decreases the incidence of HHV-6B viremia after allogeneic HCT. Blood, 2020, 04-23, Volume: 135, Issue:17 Topics: Administration, Oral; Adolescent; Adult; Aged; Antiviral Agents; Cohort Studies; Cytosine; DNA, Viral; Female; Follow-Up Studies; Graft vs Host Disease; Hematologic Neoplasms; Hematopoietic Stem Cell Transplantation; Herpesvirus 6, Human; Humans; Incidence; Male; Middle Aged; Organophosphonates; Prognosis; Randomized Controlled Trials as Topic; Roseolovirus Infections; United States; Viral Load; Viremia; Virus Activation; Young Adult	2020
Is antiviral therapy against HHV-6B beneficial? Blood, 2020, 04-23, Volume: 135, Issue:17 Topics: Antiviral Agents; Cytosine; Hematopoietic Stem Cell Transplantation; Herpesvirus 6, Human; Humans; Incidence; Organophosphonates; Roseolovirus Infections; Viremia	2020
Brincidofovir for the treatment of human adenovirus infection in pediatric solid organ transplant recipients: A case series. Pediatric transplantation, 2020, Volume: 24, Issue:7 Topics: Adenovirus Infections, Human; Adolescent; Antiviral Agents; Cytosine; Female; Follow-Up Studies; Humans; Infant; Kidney Transplantation; Liver Transplantation; Male; Organophosphonates; Postoperative Complications; Retrospective Studies; Transplant Recipients; Transplantation, Homologous; Young Adult	2020
Effect of brincidofovir on adenovirus and A549 cells transcriptome profiles. Antiviral research, 2020, Volume: 182 Topics: A549 Cells; Adenoviruses, Human; Antiviral Agents; Cytosine; Host Microbial Interactions; Humans; Organophosphonates; Transcriptome; Virus Replication	2020
A quantitative LC-MS/MS method for the determination of tissue brincidofovir and cidofovir diphosphate in a MuPyV-infected mouse model. Biomedical chromatography : BMC, 2021, Volume: 35, Issue:5 Topics: Animals; Antiviral Agents; Brain Chemistry; Chromatography, High Pressure Liquid; Cidofovir; Cytosine; Kidney; Mice; Mice, Inbred C57BL; Organophosphonates; Polyomavirus Infections; Spleen; Tandem Mass Spectrometry	2021
Initial Experience Treating HPV-Related Laryngeal Diseases with Oral Brincidofovir: A Pilot Study. The Annals of otology, rhinology, and laryngology, 2021, Volume: 130, Issue:12 Topics: Administration, Oral; Adult; Alphapapillomavirus; Antiviral Agents; Cytosine; Dose-Response Relationship, Drug; Humans; Laryngeal Diseases; Laryngoscopy; Larynx; Male; Middle Aged; Organophosphonates; Papillomavirus Infections; Pilot Projects	2021
A human recombinant analogue to plasma-derived vaccinia immunoglobulin prophylactically and therapeutically protects against lethal orthopoxvirus challenge. Antiviral research, 2021, Volume: 195 Topics: Animals; Antiviral Agents; Benzamides; Cell Line; Chlorocebus aethiops; Cytosine; Female; Humans; Immunoglobulins; Isoindoles; Mice; Mice, Inbred BALB C; Organophosphonates; Orthopoxvirus; Smallpox; Smallpox Vaccine; Vaccines, DNA; Vaccinia	2021
Safety and efficacy of brincidofovir for Adenovirus infection in children receiving allogeneic stem cell transplantation: an AIEOP retrospective analyses. Bone marrow transplantation, 2021, Volume: 56, Issue:12 Topics: Adenoviridae Infections; Antiviral Agents; Cytosine; Hematopoietic Stem Cell Transplantation; Humans; Organophosphonates; Retrospective Studies	2021
Sensitivity of Human Mastadenovirus, the Causal Agent of Pharyngoconjunctival Fever, Epidemic Keratoconjunctivitis, and Hemorrhagic Cystitis in Immunocompromised Individuals, to Brincidofovir. Microbiology spectrum, 2022, 02-23, Volume: 10, Issue:1 Topics: Adenoviridae Infections; Adenovirus Infections, Human; Cystitis; Cytosine; Humans; Immunocompromised Host; Keratoconjunctivitis; Mastadenovirus; Organophosphonates	2022