cytochrome-c-t and phenylisothiocyanate

cytochrome-c-t has been researched along with phenylisothiocyanate* in 1 studies

Other Studies

1 other study(ies) available for cytochrome-c-t and phenylisothiocyanate

Article	Year
Dietary isothiocyanates modify mitochondrial functions through their electrophilic reaction. Bioscience, biotechnology, and biochemistry, 2005, Volume: 69, Issue:12 We found that both benzyl isothiocyanate (ITC) and phenyl ITC inhibited respiration in the mitochondria in an electrophilic reaction-dependent manner. ITC-induced mitochondrial swelling and cytochrome c release were prevented by cyclosporin A, indicating that they are mediated through the ITC moiety-dependent reaction to critical thiol groups for the opening of membrane permeability transition-dependent pores. Topics: Animals; Cell Death; Cyclosporine; Cytochromes c; Diet; Dose-Response Relationship, Drug; In Vitro Techniques; Isothiocyanates; Male; Mitochondria, Liver; Mitochondrial Swelling; Oxidative Phosphorylation; Permeability; Rats; Signal Transduction; Thiocarbamates; Thiocyanates	2005

Article

Year

Dietary isothiocyanates modify mitochondrial functions through their electrophilic reaction.

Bioscience, biotechnology, and biochemistry, 2005, Volume: 69, Issue:12

We found that both benzyl isothiocyanate (ITC) and phenyl ITC inhibited respiration in the mitochondria in an electrophilic reaction-dependent manner. ITC-induced mitochondrial swelling and cytochrome c release were prevented by cyclosporin A, indicating that they are mediated through the ITC moiety-dependent reaction to critical thiol groups for the opening of membrane permeability transition-dependent pores.

Topics: Animals; Cell Death; Cyclosporine; Cytochromes c; Diet; Dose-Response Relationship, Drug; In Vitro Techniques; Isothiocyanates; Male; Mitochondria, Liver; Mitochondrial Swelling; Oxidative Phosphorylation; Permeability; Rats; Signal Transduction; Thiocarbamates; Thiocyanates

2005