cytidine triphosphate has been researched along with lamivudine in 35 studies
Timeframe | Studies, this research(%) | All Research% |
---|---|---|
pre-1990 | 0 (0.00) | 18.7374 |
1990's | 0 (0.00) | 18.2507 |
2000's | 28 (80.00) | 29.6817 |
2010's | 6 (17.14) | 24.3611 |
2020's | 1 (2.86) | 2.80 |
Authors | Studies |
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Klarmann, GJ; North, TW; Preston, BD; Schinazi, RF; Smith, RA | 1 |
García, H; Rodriguez, JF; Rodriguez, JL; Rosario, O; Santana, J | 1 |
Anderson, PL; Brundage, RC; Bushman, LR; Fletcher, CV; Kakuda, TN; Kawle, SP; Remmel, RP; Weller, D | 1 |
Darque, A; Moore, JD; Sommadossi, JP; Valette, G; Zhou, XJ | 1 |
Back, DJ; Hoggard, PG; Johnson, MA; Kewn, S; Sales, SD | 1 |
Arnold, E; Das, K; Gibbs, CS; Sarafianos, SG; Westland, CE; Xiong, X; Yang, H | 1 |
Copeland, WC; Lim, SE | 1 |
Anderson, KS; Feng, JY; Johnson, AA; Johnson, KA | 1 |
Deville-Bonne, D; Faraj, A; Kreimeyer, A; Sarfati, R; Schneider, B; Sommadossi, JP; Veron, M | 1 |
Arnold, E; Boyer, PL; Clark, PK; Gao, HQ; Hughes, SH; Sarafianos, SG | 1 |
Duan, C; Kuritzkes, DR; McHenry, CS; Petropoulos, CJ; Poticha, D; Stoeckli, TC; Whitcomb, JM | 1 |
Ahn, KJ; Choi, KM; Hong, JS; Jeong, GY; Ki, CS; Kim, DK; Kim, JW | 1 |
Anderson, KS | 1 |
Furman, P; Martin, P; Pichoud, C; Seignères, B; Trépo, C; Zoulim, F | 1 |
Hurwitz, SJ; Schinazi, RF | 1 |
Anderson, KS; Feng, JY; Furman, PA; Jeffrey, JL; Qi, CC | 1 |
Bacheler, L; Erickson-Viitanen, S; Gallagher, K; Garber, S; Geleziunas, R; Otto, MJ; Schinazi, RF; Shi, G; Wu, JT; Zhang, H | 1 |
Anderson, PL; Fletcher, CV; Kakuda, TN; Kawle, S | 1 |
Back, DJ; Beijnen, JH; Crommentuyn, KM; Hoggard, PG; Huitema, AD; Kewn, S; Lange, JM; Prins, JM; Sankatsing, SU; Sparidans, RW | 1 |
Clark, N; Guyer, B; Hawkins, T; Kearney, BP; St Claire, RL; Veikley, W | 1 |
Baofeng, W; Lichao, Y; Shuangsuo, D; Xin, Z; Yan'an, C; Yunru, C; Zhengguo, Z | 1 |
Mellors, JW; Parikh, UM; Sheen, CW; Sluis-Cremer, N; Torres, PS; Zelina, S | 1 |
Chatterjee, DK; Eisenhauer, BM; Gotte, M; Hecht, SM; Klarmann, GJ; Le Grice, SF; Pata, JD; Zhang, Y | 1 |
Anderson, PL; Bushman, LR; Fletcher, CV; Gerber, J; King, T; Meditz, A; Predhomme, J; Zheng, JH | 1 |
Acosta, EP; Bassett, R; Eron, JJ; Fischl, MA; Johnson, VA; Kuritzkes, DR; Long, MC; Moore, JD; Sommadossi, JP | 1 |
Agrofoglio, L; Bénech, H; Negredo, E; Pruvost, A; Théodoro, F | 1 |
Asif, G; Hurwitz, SJ; Schinazi, RF | 1 |
Anderson, PL; King, T; MaWhinney, S; Zheng, JH | 1 |
Johnson, KA; Kellinger, MW | 1 |
Bazzoli, C; Bénech, H; Duval, X; Mentré, F; Retout, S; Rey, E; Salmon, D; Tréluyer, JM | 1 |
Amara, A; Back, DJ; Boffito, M; Else, LJ; Emery, S; Fahey, P; Hill, A; Jackson, A; Khoo, S; Lin, E; Puls, R; Siccardi, M; Tjia, J; Watson, V | 1 |
Anderson, PL; Bushman, LR; Gardner, EM; Klein, B; Lichtenstein, K; Mawhinney, S; Meditz, A; Predhomme, J; Rower, JE; Zheng, JH | 1 |
Fätkenheuer, G; Hartmann, P; Jung, N; Lehmann, C; Rubbert, A; Schömig, E; Taubert, D | 1 |
Bridges, AS; Cohen, MS; Dumond, JB; Fiscus, SA; Forrest, A; Kashuba, AD; Kendrick, R; Reddy, YS; Troiani, L; Yang, KH | 1 |
Beksinska, M; Brown, TT; Eneh, P; Fowler, MG; Isingel, E; Kabwigu, S; Kaiser, T; Kiweewa Matovu, F; Nakalega, R; Nicol, MR; Staley, C; Sykes, C | 1 |
1 review(s) available for cytidine triphosphate and lamivudine
Article | Year |
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Perspectives on the molecular mechanism of inhibition and toxicity of nucleoside analogs that target HIV-1 reverse transcriptase.
Topics: Anti-HIV Agents; Cytidine Triphosphate; Deoxycytosine Nucleotides; Dideoxynucleotides; DNA Polymerase gamma; DNA-Directed DNA Polymerase; HIV Reverse Transcriptase; HIV-1; Humans; Lamivudine; Nucleosides; Reverse Transcriptase Inhibitors; Stereoisomerism; Zalcitabine | 2002 |
4 trial(s) available for cytidine triphosphate and lamivudine
Article | Year |
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Zidovudine triphosphate and lamivudine triphosphate concentration-response relationships in HIV-infected persons.
Topics: Adolescent; Adult; Aged; Anti-HIV Agents; CD4 Lymphocyte Count; Cytidine Triphosphate; Dideoxynucleotides; Dose-Response Relationship, Drug; Drug Therapy, Combination; HIV; HIV Infections; Humans; Lamivudine; Leukocytes, Mononuclear; Middle Aged; Prospective Studies; Regression Analysis; Reverse Transcriptase Inhibitors; RNA, Viral; Thymine Nucleotides; Zidovudine | 2000 |
Antiviral dynamics and sex differences of zidovudine and lamivudine triphosphate concentrations in HIV-infected individuals.
Topics: Adult; Anti-HIV Agents; CD4 Lymphocyte Count; Chromatography, High Pressure Liquid; Cytidine Triphosphate; Dideoxynucleotides; Female; Half-Life; HIV Infections; Humans; Immunoassay; Lamivudine; Male; Prospective Studies; Reverse Transcriptase Inhibitors; RNA, Viral; Severity of Illness Index; Sex Factors; Zidovudine | 2003 |
Effect of mycophenolate mofetil on the pharmacokinetics of antiretroviral drugs and on intracellular nucleoside triphosphate pools.
Topics: Acquired Immunodeficiency Syndrome; Adult; Anti-Inflammatory Agents, Non-Steroidal; Anti-Retroviral Agents; Cytidine Triphosphate; Deoxycytosine Nucleotides; Deoxyguanine Nucleotides; Dideoxynucleotides; Drug Interactions; HIV-1; Humans; Lamivudine; Male; Metabolic Clearance Rate; Middle Aged; Mycophenolic Acid | 2004 |
Pharmacokinetics of lamivudine and lamivudine-triphosphate after administration of 300 milligrams and 150 milligrams once daily to healthy volunteers: results of the ENCORE 2 study.
Topics: Administration, Oral; Adolescent; Adult; Aged; Area Under Curve; Biological Availability; Chromatography, High Pressure Liquid; Cross-Over Studies; Cytidine Triphosphate; Dideoxynucleotides; Drug Administration Schedule; Female; Humans; Lamivudine; Leukocytes, Mononuclear; Male; Middle Aged; Reverse Transcriptase Inhibitors; Tandem Mass Spectrometry; Therapeutic Equivalency; United Kingdom; Young Adult | 2012 |
30 other study(ies) available for cytidine triphosphate and lamivudine
Article | Year |
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Site-specific incorporation of nucleoside analogs by HIV-1 reverse transcriptase and the template grip mutant P157S. Template interactions influence substrate recognition at the polymerase active site.
Topics: Catalytic Domain; Cytidine Triphosphate; Dideoxynucleotides; Dose-Response Relationship, Drug; Drug Resistance; HIV Reverse Transcriptase; HIV-1; Lamivudine; Mutation; Proline; Reverse Transcriptase Inhibitors; Thionucleosides; Thiophenes; Thymine Nucleotides; Transcription, Genetic; Zalcitabine; Zidovudine | 2000 |
Simultaneous quantitation of intracellular zidovudine and lamivudine triphosphates in human immunodeficiency virus-infected individuals.
Topics: Anti-HIV Agents; Chromatography, Ion Exchange; Cytidine Triphosphate; Dideoxynucleotides; HIV Infections; Humans; Lamivudine; Reference Standards; Thymine Nucleotides; Zidovudine | 2000 |
Simultaneous quantitation of the 5'-triphosphate metabolites of zidovudine, lamivudine, and stavudine in peripheral mononuclear blood cells of HIV infected patients by high-performance liquid chromatography tandem mass spectrometry.
Topics: Anti-HIV Agents; Calibration; Chromatography, High Pressure Liquid; Cytidine Triphosphate; Dideoxynucleotides; Drug Therapy, Combination; HIV Infections; Humans; Lamivudine; Mass Spectrometry; Monocytes; Reference Standards; Sensitivity and Specificity; Stavudine; Thymine Nucleotides; Zidovudine | 2000 |
The intracellular activation of lamivudine (3TC) and determination of 2'-deoxycytidine-5'-triphosphate (dCTP) pools in the presence and absence of various drugs in HepG2 cells.
Topics: Anti-HIV Agents; Cell Survival; Cytidine Triphosphate; Deoxycytosine Nucleotides; Dideoxynucleotides; Drug Interactions; Humans; Hydroxyurea; Lamivudine; Methotrexate; Phosphorylation; Tumor Cells, Cultured; Vidarabine | 2000 |
Molecular modeling and biochemical characterization reveal the mechanism of hepatitis B virus polymerase resistance to lamivudine (3TC) and emtricitabine (FTC).
Topics: Acyclovir; Adenine; Amino Acid Sequence; Antiviral Agents; Cytidine Triphosphate; Deoxycytidine; Dideoxynucleotides; Drug Resistance, Microbial; Emtricitabine; Guanine; Hepatitis B virus; Humans; Lamivudine; Models, Molecular; Molecular Sequence Data; Organophosphonates; Protein Conformation; Reverse Transcriptase Inhibitors; RNA-Directed DNA Polymerase; Sequence Homology, Amino Acid | 2001 |
Differential incorporation and removal of antiviral deoxynucleotides by human DNA polymerase gamma.
Topics: Anti-HIV Agents; Cytidine Triphosphate; Deoxyguanine Nucleotides; Deoxyribonucleotides; Dideoxynucleotides; DNA; DNA Polymerase gamma; DNA Replication; DNA-Directed DNA Polymerase; Exodeoxyribonucleases; Humans; Kinetics; Lamivudine; Nucleic Acid Synthesis Inhibitors; Reverse Transcriptase Inhibitors; Stavudine; Substrate Specificity; Thymine Nucleotides; Zalcitabine; Zidovudine | 2001 |
Insights into the molecular mechanism of mitochondrial toxicity by AIDS drugs.
Topics: Acquired Immunodeficiency Syndrome; Anti-HIV Agents; Cytidine Triphosphate; Deoxycytosine Nucleotides; Dideoxynucleotides; DNA; DNA Polymerase gamma; DNA Replication; DNA-Directed DNA Polymerase; DNA, Mitochondrial; Exodeoxyribonucleases; Humans; Kinetics; Lamivudine; Mitochondria; Nucleic Acid Synthesis Inhibitors; Reverse Transcriptase Inhibitors; Zalcitabine | 2001 |
NDP kinase reactivity towards 3TC nucleotides.
Topics: Animals; Anti-HIV Agents; Binding, Competitive; Computer Simulation; Cytidine Triphosphate; Dictyostelium; Dideoxynucleotides; Humans; Kinetics; Lamivudine; Nucleoside-Diphosphate Kinase; Phosphorylation; Substrate Specificity | 2001 |
YADD mutants of human immunodeficiency virus type 1 and Moloney murine leukemia virus reverse transcriptase are resistant to lamivudine triphosphate (3TCTP) in vitro.
Topics: Alanine; Animals; Anti-HIV Agents; Cytidine Triphosphate; Dideoxynucleotides; Drug Resistance, Microbial; HIV Reverse Transcriptase; HIV-1; Humans; Isoleucine; Lamivudine; Methionine; Molecular Conformation; Moloney murine leukemia virus; Point Mutation; RNA-Directed DNA Polymerase; Virus Replication | 2001 |
Inhibition of purified recombinant reverse transcriptase from wild-type and zidovudine-resistant clinical isolates of human immunodeficiency virus type 1 by zidovudine, stavudine, and lamivudine triphosphates.
Topics: Anti-HIV Agents; Cytidine Triphosphate; Dideoxynucleotides; Dose-Response Relationship, Drug; Drug Resistance, Microbial; Escherichia coli; HIV Infections; HIV-1; Lamivudine; Recombinant Proteins; Reverse Transcriptase Inhibitors; RNA-Directed DNA Polymerase; Stavudine; Thymine Nucleotides; Transfection; Zidovudine | 2001 |
Identification of lamin A/C ( LMNA) gene mutations in Korean patients with autosomal dominant Emery-Dreifuss muscular dystrophy and limb-girdle muscular dystrophy 1B.
Topics: Adult; Cytidine Triphosphate; Dideoxynucleotides; DNA Mutational Analysis; Female; Genes, Dominant; Genetic Predisposition to Disease; Humans; Korea; Lamin Type A; Lamins; Lamivudine; Muscular Dystrophies; Muscular Dystrophy, Emery-Dreifuss; Mutation; Nuclear Proteins; Pedigree | 2002 |
Inhibitory activity of dioxolane purine analogs on wild-type and lamivudine-resistant mutants of hepadnaviruses.
Topics: Animals; Arabinofuranosylcytosine Triphosphate; Arabinofuranosyluracil; Carcinoma, Hepatocellular; Cytidine Triphosphate; Dioxolanes; DNA Replication; DNA-Directed DNA Polymerase; DNA, Viral; Drug Resistance, Viral; Gene Expression Regulation, Viral; Guanosine; Hepadnaviridae Infections; Hepatitis B virus; Hepatitis B Virus, Duck; Hepatitis, Viral, Animal; Hepatocytes; Humans; Lamivudine; Liver Neoplasms; Mutation; Purine Nucleosides; Reverse Transcriptase Inhibitors; Thiophenes; Tumor Cells, Cultured | 2002 |
Development of a pharmacodynamic model for HIV treatment with nucleoside reverse transcriptase and protease inhibitors.
Topics: Anti-HIV Agents; CD4 Lymphocyte Count; Cytidine Triphosphate; Dideoxynucleotides; HIV Infections; HIV Protease Inhibitors; HIV-1; Humans; Lamivudine; Models, Statistical; Reverse Transcriptase Inhibitors; Thymine Nucleotides; Viral Load; Zidovudine | 2002 |
Dioxolane guanosine 5'-triphosphate, an alternative substrate inhibitor of wild-type and mutant HIV-1 reverse transcriptase. Steady state and pre-steady state kinetic analyses.
Topics: Acquired Immunodeficiency Syndrome; Cytidine Triphosphate; Deoxycytidine Monophosphate; Deoxyguanine Nucleotides; Dideoxynucleotides; Dioxolanes; DNA, Viral; Drug Resistance, Viral; Guanosine; Guanosine Triphosphate; HIV Reverse Transcriptase; HIV-1; Lamivudine; Mutation; Reverse Transcriptase Inhibitors; Substrate Specificity; Thymidine Monophosphate; Thymine Nucleotides; Zidovudine | 2003 |
HIV-1 resistance profile of the novel nucleoside reverse transcriptase inhibitor beta-D-2',3'-dideoxy-2',3'-didehydro-5-fluorocytidine (Reverset).
Topics: Adenine; Anti-HIV Agents; Cell Line; Cytidine Triphosphate; Didanosine; Drug Resistance, Multiple, Viral; Genotype; HIV Reverse Transcriptase; HIV-1; Humans; Lamivudine; Mutation; Organophosphonates; Organophosphorus Compounds; Reverse Transcriptase Inhibitors; Species Specificity; Tenofovir; Transfection; Zalcitabine; Zidovudine | 2003 |
Intracellular pharmacokinetics of tenofovir diphosphate, carbovir triphosphate, and lamivudine triphosphate in patients receiving triple-nucleoside regimens.
Topics: Adenine; Adult; Aged; Anti-HIV Agents; Cytidine Triphosphate; Dideoxynucleosides; Dideoxynucleotides; Drug Interactions; Female; HIV Infections; Humans; Lamivudine; Leukocytes, Mononuclear; Male; Middle Aged; Organophosphonates; Prospective Studies; Tenofovir | 2005 |
Inhibition of the replication of hepatitis B virus in vitro by emodin.
Topics: Antiviral Agents; Biological Assay; Cytidine Triphosphate; Dideoxynucleotides; Emodin; Enzyme Inhibitors; Hepatitis B Antigens; Hepatitis B virus; Humans; Interferon-alpha; Lamivudine; Tumor Cells, Cultured; Virus Replication | 2006 |
Molecular mechanism by which the K70E mutation in human immunodeficiency virus type 1 reverse transcriptase confers resistance to nucleoside reverse transcriptase inhibitors.
Topics: Adenine; Amino Acid Substitution; Anti-HIV Agents; Cytidine Triphosphate; Dideoxynucleosides; Dideoxynucleotides; Drug Resistance, Multiple, Viral; Genotype; Glutamic Acid; HIV Reverse Transcriptase; HIV-1; Humans; Lamivudine; Lysine; Mutagenesis, Site-Directed; Organophosphonates; Phenotype; Reverse Transcriptase Inhibitors; Tenofovir; Thymine Nucleotides; Zidovudine | 2007 |
Investigating the "steric gate" of human immunodeficiency virus type 1 (HIV-1) reverse transcriptase by targeted insertion of unnatural amino acids.
Topics: Amino Acid Substitution; Binding Sites; Cell-Free System; Cytidine Triphosphate; Deoxycytosine Nucleotides; Dideoxynucleotides; DNA; Escherichia coli; HIV Reverse Transcriptase; HIV-1; Hydrogen Bonding; Kinetics; Lamivudine; Models, Molecular; Protein Biosynthesis; Protein Engineering; Reverse Transcriptase Inhibitors; Transcription, Genetic; Tyrosine | 2007 |
Concentrations of zidovudine- and lamivudine-triphosphate according to cell type in HIV-seronegative adults.
Topics: Adult; Anti-HIV Agents; CD4-Positive T-Lymphocytes; Cytidine Triphosphate; Dideoxynucleotides; Drug Administration Schedule; Female; HIV Seronegativity; Humans; Lamivudine; Leukocytes, Mononuclear; Male; Middle Aged; Phosphorylation; Reverse Transcriptase Inhibitors; Thymine Nucleotides; Zidovudine | 2007 |
Intracellular nucleoside triphosphate concentrations in HIV-infected patients on dual nucleoside reverse transcriptase inhibitor therapy.
Topics: Anti-HIV Agents; Cytidine Triphosphate; Dideoxynucleotides; Drug Therapy, Combination; Female; HIV Infections; Humans; Lamivudine; Leukocytes, Mononuclear; Male; Reverse Transcriptase Inhibitors; Stavudine; Thymine Nucleotides; Zidovudine | 2007 |
Specificity enhancement with LC-positive ESI-MS/MS for the measurement of nucleotides: application to the quantitative determination of carbovir triphosphate, lamivudine triphosphate and tenofovir diphosphate in human peripheral blood mononuclear cells.
Topics: Adenine; Anti-HIV Agents; Cytidine Triphosphate; Deoxyguanine Nucleotides; Dideoxynucleosides; Dideoxynucleotides; HIV Infections; Humans; Lamivudine; Leukocytes, Mononuclear; Organophosphonates; Reproducibility of Results; Spectrometry, Mass, Electrospray Ionization; Tandem Mass Spectrometry; Tenofovir | 2008 |
Development of a population simulation model for HIV monotherapy virological outcomes using lamivudine.
Topics: Anti-HIV Agents; CD4 Lymphocyte Count; Clinical Trials as Topic; Cytidine Triphosphate; Dideoxynucleotides; HIV; HIV Infections; Humans; Inhibitory Concentration 50; Kinetics; Lamivudine; Models, Biological; Monte Carlo Method; Reverse Transcriptase Inhibitors; Treatment Outcome; Viral Load | 2007 |
Cytokine and sex hormone effects on zidovudine- and lamivudine-triphosphate concentrations in vitro.
Topics: Adipocytes; Cytidine Triphosphate; Cytokines; Dideoxynucleotides; Female; Gonadal Steroid Hormones; Humans; Lamivudine; Leukocytes, Mononuclear; Male; Zidovudine | 2008 |
Nucleotide-dependent conformational change governs specificity and analog discrimination by HIV reverse transcriptase.
Topics: Chromatography, Affinity; Chromatography, Ion Exchange; Cytidine Triphosphate; Dideoxynucleotides; DNA Primers; Fluorometry; HIV Reverse Transcriptase; Kinetics; Lamivudine; Models, Chemical; Mutagenesis; Protein Binding; Protein Conformation; Substrate Specificity | 2010 |
Joint population pharmacokinetic analysis of zidovudine, lamivudine, and their active intracellular metabolites in HIV patients.
Topics: Adult; Anti-HIV Agents; Chromatography, Liquid; Cytidine Triphosphate; Dideoxynucleotides; Female; Humans; Lamivudine; Male; Middle Aged; Models, Theoretical; Sex Factors; Tandem Mass Spectrometry; Young Adult; Zidovudine | 2011 |
Effect of HIV-1 infection and sex on the cellular pharmacology of the antiretroviral drugs zidovudine and lamivudine.
Topics: Adult; Anti-HIV Agents; Black or African American; Cytidine Triphosphate; Dideoxynucleotides; Female; HIV Infections; Humans; Lamivudine; Longitudinal Studies; Male; Prospective Studies; Sex Factors; Thymine Nucleotides; Zidovudine | 2012 |
Organic cation transporters OCT1 and OCT2 determine the accumulation of lamivudine in CD4 cells of HIV-infected patients.
Topics: Adult; Antiretroviral Therapy, Highly Active; CD4-Positive T-Lymphocytes; Cytidine Triphosphate; Dideoxynucleotides; Female; HIV Infections; HIV Protease Inhibitors; HIV-1; Humans; Lamivudine; Male; Middle Aged; Nelfinavir; Organic Cation Transport Proteins; Organic Cation Transporter 1; Organic Cation Transporter 2; Phosphorylation; Real-Time Polymerase Chain Reaction; Ritonavir; RNA, Messenger; Tandem Mass Spectrometry; Transfection; Young Adult | 2013 |
Pharmacokinetic Modeling of Lamivudine and Zidovudine Triphosphates Predicts Differential Pharmacokinetics in Seminal Mononuclear Cells and Peripheral Blood Mononuclear Cells.
Topics: Adult; Anti-HIV Agents; Biological Availability; Biological Transport; Blood Cells; Computer Simulation; Cytidine Triphosphate; Dideoxynucleotides; HIV Infections; HIV-1; Humans; Lamivudine; Leukocytes, Mononuclear; Male; Models, Statistical; Semen; Thymine Nucleotides; Time Factors; Zidovudine | 2015 |
Depot Medroxyprogesterone Acetate and the Vaginal Microbiome as Modifiers of Tenofovir Diphosphate and Lamivudine Triphosphate Concentrations in the Female Genital Tract of Ugandan Women: Implications for Tenofovir Disoproxil Fumarate/Lamivudine in Preexp
Topics: Adenine; Anti-HIV Agents; Cytidine Triphosphate; Dideoxynucleotides; Emtricitabine; Female; HIV Infections; Humans; Lamivudine; Medroxyprogesterone Acetate; Microbiota; Organophosphates; Pre-Exposure Prophylaxis; Tenofovir; Uganda | 2020 |