Page last updated: 2024-08-17

cytidine triphosphate and glutamine

cytidine triphosphate has been researched along with glutamine in 24 studies

Research

Studies (24)

TimeframeStudies, this research(%)All Research%
pre-19904 (16.67)18.7374
1990's7 (29.17)18.2507
2000's7 (29.17)29.6817
2010's4 (16.67)24.3611
2020's2 (8.33)2.80

Authors

AuthorsStudies
McPartland, RP; Weinfeld, H1
Kantrowitz, ER; Middleton, SA; Tauc, P; Vachette, P1
Kantrowitz, ER; Stebbins, JW; Zhang, Y1
Lewis, DA; Villafranca, JJ1
Fisher, JM; Rabinovitz, M1
Chu, EH; McLaren, JD1
Adeline, MT; Carman, GM; Flocco, MT; McDonough, VM; Ozier-Kalogeropoulos, O; Yang, WL1
Bruno, ME; Carman, GM; Yang, WL1
Carman, GM; Gorman, JA; O'Brien, DJ; Ostrander, DB1
Jiang, P; Ninfa, AJ; Peliska, JA1
Huang, Q; Lau, SS; Monks, TJ1
Bearne, SL; Hekmat, O; Macdonnell, JE1
Sigurskjold, BW; Willemoës, M1
Bearne, SL; Iyengar, A2
Bearne, SL; Hewitt, KA; Iyengar, A; Lunn, F; Simard, D1
Willemoës, M1
Bearne, SL; Lunn, FA; MacDonnell, JE1
Brumby, AM; Humbert, PO; Manning, SA; Parisot, JP; Richardson, HE; Schlosser, T; Street, IP; Willoughby, LF1
Calise, SJ; Carcamo, WC; Chan, EK; Krueger, C; Purich, DL; Yin, JD1
Bearne, SL; McCluskey, GD1
Raushel, FM; Taylor, ZW1
Ajazi, A; Bachi, A; Bruhn, C; Choudhary, R; Tronci, L1
Bearne, SL; Guo, CJ; Liu, JL1

Reviews

1 review(s) available for cytidine triphosphate and glutamine

ArticleYear
GTP-Dependent Regulation of CTP Synthase: Evolving Insights into Allosteric Activation and NH
    Biomolecules, 2022, 04-29, Volume: 12, Issue:5

    Topics: Adenosine Triphosphate; Allosteric Regulation; Carbon-Nitrogen Ligases; Cryoelectron Microscopy; Cytidine Triphosphate; Glutaminase; Glutamine; Guanosine Triphosphate; Nitric Oxide Synthase; Uridine Triphosphate

2022

Other Studies

23 other study(ies) available for cytidine triphosphate and glutamine

ArticleYear
Cooperative effects of CTP on calf liver CTP synthetase.
    The Journal of biological chemistry, 1979, Nov-25, Volume: 254, Issue:22

    Topics: Adenosine Triphosphate; Animals; Cattle; Cytidine Triphosphate; Cytosine Nucleotides; Glutamine; Kinetics; Ligases; Liver; Uridine Triphosphate

1979
Structural consequences of the replacement of Glu239 by Gln in the catalytic chain of Escherichia coli aspartate transcarbamylase.
    Journal of molecular biology, 1990, Jul-05, Volume: 214, Issue:1

    Topics: Adenosine Triphosphate; Amino Acid Sequence; Aspartate Carbamoyltransferase; Aspartic Acid; Carbamyl Phosphate; Cytidine Triphosphate; Escherichia coli; Glutamates; Glutamic Acid; Glutamine; Phosphonoacetic Acid; Protein Engineering; Structure-Activity Relationship; X-Ray Diffraction

1990
Importance of residues Arg-167 and Gln-231 in both the allosteric and catalytic mechanisms of Escherichia coli aspartate transcarbamoylase.
    Biochemistry, 1990, Apr-24, Volume: 29, Issue:16

    Topics: Adenosine Triphosphate; Allosteric Regulation; Aspartate Carbamoyltransferase; Aspartic Acid; Binding Sites; Catalysis; Cytidine Triphosphate; Escherichia coli; Glutamine; Kinetics; Mutation; Phosphonoacetic Acid; Protein Conformation

1990
Investigation of the mechanism of CTP synthetase using rapid quench and isotope partitioning methods.
    Biochemistry, 1989, Oct-17, Volume: 28, Issue:21

    Topics: Adenosine Triphosphatases; Adenosine Triphosphate; Carbon-Nitrogen Ligases; Chemical Phenomena; Chemistry; Cytidine Triphosphate; Cytosine Nucleotides; Escherichia coli; Glutamine; Guanosine Triphosphate; Kinetics; Ligases; Phosphorus Radioisotopes; Phosphorylation; Uridine Triphosphate

1989
Evidence for a copper:S-(methylthio)-L-homocysteine complex as a glutamine antagonist of cytidine triphosphate synthesis in L1210 murine leukemia cells.
    Molecular pharmacology, 1988, Volume: 34, Issue:3

    Topics: Animals; Anthranilate Synthase; Binding Sites; Cell Survival; Copper; Cytidine Triphosphate; Cytosine Nucleotides; Disulfides; Glutamine; Homocysteine; Leukemia L1210; Metals; Mice; Nitrogenous Group Transferases; Organometallic Compounds; Transferases; Tumor Cells, Cultured

1988
Apparent synergism between amino donors for CTP synthesis in Chinese hamster fibroblasts.
    Molecular and cellular biochemistry, 1983, Volume: 57, Issue:2

    Topics: Animals; Arginine; Bicarbonates; Carbon-Nitrogen Ligases; Cell Line; Cricetinae; Cricetulus; Cytidine Triphosphate; Cytosine Nucleotides; Drug Synergism; Glutamine; Ligases; Lung; Uridine Triphosphate

1983
Purification and characterization of CTP synthetase, the product of the URA7 gene in Saccharomyces cerevisiae.
    Biochemistry, 1994, Sep-06, Volume: 33, Issue:35

    Topics: Base Sequence; Blotting, Western; Carbon-Nitrogen Ligases; Cloning, Molecular; Cytidine Triphosphate; Glutamine; Guanosine Triphosphate; Hydrogen-Ion Concentration; Kinetics; Ligases; Magnesium; Molecular Sequence Data; Precipitin Tests; Recombinant Proteins; Saccharomyces cerevisiae; Uridine Triphosphate

1994
Regulation of yeast CTP synthetase activity by protein kinase C.
    The Journal of biological chemistry, 1996, May-10, Volume: 271, Issue:19

    Topics: Adenosine Triphosphate; Carbon-Nitrogen Ligases; Cytidine Triphosphate; Enzyme Activation; Glutamine; Kinetics; Ligases; Phosphates; Phosphorus Radioisotopes; Phosphorylation; Protein Kinase C; Saccharomyces cerevisiae; Substrate Specificity

1996
Effect of CTP synthetase regulation by CTP on phospholipid synthesis in Saccharomyces cerevisiae.
    The Journal of biological chemistry, 1998, Jul-24, Volume: 273, Issue:30

    Topics: Amino Acid Substitution; Antineoplastic Agents; Carbon-Nitrogen Ligases; Cytidine; Cytidine Triphosphate; Glutamine; Lysine; Mutagenesis, Site-Directed; Phospholipids; Pyrimidines; Saccharomyces cerevisiae

1998
Enzymological characterization of the signal-transducing uridylyltransferase/uridylyl-removing enzyme (EC 2.7.7.59) of Escherichia coli and its interaction with the PII protein.
    Biochemistry, 1998, Sep-15, Volume: 37, Issue:37

    Topics: Bacterial Proteins; Binding, Competitive; Cytidine Triphosphate; Enzyme Activation; Escherichia coli; Glutamate-Ammonia Ligase; Glutamine; Manganese; Nicotinamide-Nucleotide Adenylyltransferase; Nucleotidyltransferases; PII Nitrogen Regulatory Proteins; Pyrimidine Nucleotides; Substrate Specificity; Uridine Triphosphate

1998
Induction of gadd153 mRNA by nutrient deprivation is overcome by glutamine.
    The Biochemical journal, 1999, Jul-01, Volume: 341 ( Pt 1)

    Topics: Animals; Aspartic Acid; CCAAT-Enhancer-Binding Proteins; Cells, Cultured; Culture Media; Cytidine; Cytidine Triphosphate; Diazooxonorleucine; DNA Damage; DNA-Binding Proteins; Epithelial Cells; Gene Expression Regulation; Glutamine; Isoxazoles; Ketoglutaric Acids; Kidney Tubules, Proximal; RNA, Messenger; Salts; Swine; Transcription Factor CHOP; Transcription Factors; Uridine

1999
Inhibition of Escherichia coli CTP synthase by glutamate gamma-semialdehyde and the role of the allosteric effector GTP in glutamine hydrolysis.
    The Biochemical journal, 2001, May-15, Volume: 356, Issue:Pt 1

    Topics: Allosteric Regulation; Aminobutyrates; Carbon-Nitrogen Ligases; Cysteine; Cytidine Triphosphate; Enzyme Activation; Escherichia coli; Glutamates; Glutamine; Hydrolysis; Kinetics; Models, Chemical; Mutagenesis, Site-Directed; Pyrroles; Pyrrolidonecarboxylic Acid; Quaternary Ammonium Compounds; Recombinant Proteins

2001
Steady-state kinetics of the glutaminase reaction of CTP synthase from Lactococcus lactis. The role of the allosteric activator GTP incoupling between glutamine hydrolysis and CTP synthesis.
    European journal of biochemistry, 2002, Volume: 269, Issue:19

    Topics: Allosteric Regulation; Calorimetry; Carbon-Nitrogen Ligases; Cytidine Triphosphate; Glutaminase; Glutamine; Guanosine Triphosphate; Hydrolysis; Kinetics; Lactococcus lactis; Models, Biological

2002
Aspartate-107 and leucine-109 facilitate efficient coupling of glutamine hydrolysis to CTP synthesis by Escherichia coli CTP synthase.
    The Biochemical journal, 2003, Feb-01, Volume: 369, Issue:Pt 3

    Topics: Alanine; Amino Acid Sequence; Aspartic Acid; Carbon-Nitrogen Ligases; Circular Dichroism; Conserved Sequence; Cytidine Triphosphate; Dimerization; Escherichia coli Proteins; Glutamine; Guanosine Triphosphate; Hydrolysis; Leucine; Molecular Sequence Data; Mutagenesis, Site-Directed

2003
An assay for cytidine 5(')-triphosphate synthetase glutaminase activity using high performance liquid chromatography.
    Analytical biochemistry, 2002, Sep-15, Volume: 308, Issue:2

    Topics: Adenosine Triphosphate; Carbon-Nitrogen Ligases; Chromatography, High Pressure Liquid; Colorimetry; Cytidine Triphosphate; Glutaminase; Glutamine; Guanosine Triphosphate; Kinetics; Mutation; Uridine Triphosphate

2002
Limited proteolysis of Escherichia coli cytidine 5'-triphosphate synthase. Identification of residues required for CTP formation and GTP-dependent activation of glutamine hydrolysis.
    European journal of biochemistry, 2003, Volume: 270, Issue:10

    Topics: Amino Acid Sequence; Arginine; Binding Sites; Carbon-Nitrogen Ligases; Catalysis; Circular Dichroism; Cytidine Triphosphate; Dimerization; Dose-Response Relationship, Drug; Electrophoresis, Polyacrylamide Gel; Enzyme Activation; Escherichia coli; Glutaminase; Glutamine; Guanosine Triphosphate; Hydrolysis; Kinetics; Lysine; Models, Chemical; Models, Genetic; Molecular Sequence Data; Mutagenesis, Site-Directed; Mutation; Plasmids; Protein Binding; Protein Structure, Secondary; Protein Structure, Tertiary; Proteins; Sequence Homology, Amino Acid; Time Factors; Trypsin

2003
Competition between ammonia derived from internal glutamine hydrolysis and hydroxylamine present in the solution for incorporation into UTP as catalysed by Lactococcus lactis CTP synthase.
    Archives of biochemistry and biophysics, 2004, Apr-01, Volume: 424, Issue:1

    Topics: Ammonia; Binding, Competitive; Carbon-Nitrogen Ligases; Catalysis; Cytidine Triphosphate; Enzyme Inhibitors; Glutamates; Glutamine; Guanosine Triphosphate; Hydrolysis; Hydroxylamine; Kinetics; Lactococcus lactis; Protein Binding; Protein Subunits; Solutions; Uridine Triphosphate

2004
Inhibition of E. coli CTP synthase by the "positive" allosteric effector GTP.
    Biochimica et biophysica acta, 2004, Jun-01, Volume: 1699, Issue:1-2

    Topics: Allosteric Regulation; Ammonia; Carbon-Nitrogen Ligases; Cytidine Triphosphate; Escherichia coli; Glutaminase; Glutamine; Guanosine Triphosphate; Hydrolysis; Kinetics; Uridine Triphosphate

2004
An in vivo large-scale chemical screening platform using Drosophila for anti-cancer drug discovery.
    Disease models & mechanisms, 2013, Volume: 6, Issue:2

    Topics: Animals; Antineoplastic Agents; Benzamides; Biological Availability; Cell Proliferation; Cytidine Triphosphate; Diphenylamine; Drosophila melanogaster; Drug Screening Assays, Antitumor; Glutamine; Isoxazoles; Neoplasms; Pharmacogenetics; Pilot Projects

2013
Glutamine deprivation initiates reversible assembly of mammalian rods and rings.
    Cellular and molecular life sciences : CMLS, 2014, Volume: 71, Issue:15

    Topics: Biosynthetic Pathways; Carbon-Nitrogen Ligases; Cytidine Triphosphate; Glutamate-Ammonia Ligase; Glutamine; Guanosine Triphosphate; HeLa Cells; Humans; IMP Dehydrogenase

2014
"Pinching" the ammonia tunnel of CTP synthase unveils coordinated catalytic and allosteric-dependent control of ammonia passage.
    Biochimica et biophysica acta. General subjects, 2018, Volume: 1862, Issue:12

    Topics: Adenosine Triphosphate; Alkylation; Allosteric Regulation; Amino Acid Sequence; Ammonia; Binding Sites; Carbon-Nitrogen Ligases; Catalysis; Chlorides; Crystallography, X-Ray; Cytidine Triphosphate; Glutaminase; Glutamine; Hydrolysis; Kinetics; Mutagenesis, Site-Directed; Protein Conformation; Uridine Triphosphate; Valine

2018
Manganese-Induced Substrate Promiscuity in the Reaction Catalyzed by Phosphoglutamine Cytidylyltransferase from Campylobacter jejuni.
    Biochemistry, 2019, 04-23, Volume: 58, Issue:16

    Topics: Amides; Bacterial Proteins; Biocatalysis; Campylobacter jejuni; Cytidine Triphosphate; Glutamine; Manganese; Models, Chemical; Molecular Structure; Nucleotidyltransferases; Phosphoric Acids; Substrate Specificity

2019
CTP sensing and Mec1ATR-Rad53CHK1/CHK2 mediate a two-layered response to inhibition of glutamine metabolism.
    PLoS genetics, 2022, Volume: 18, Issue:3

    Topics: Cytidine Triphosphate; Glutamine

2022