Page last updated: 2024-08-17

cytidine monophosphate and cytarabine

cytidine monophosphate has been researched along with cytarabine in 28 studies

Research

Studies (28)

TimeframeStudies, this research(%)All Research%
pre-199010 (35.71)18.7374
1990's16 (57.14)18.2507
2000's2 (7.14)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Dorr, RT; Iyengar, BS; Remers, WA1
Buchheit, DJ; Hong, CI; Kirisits, AJ; Nechaev, A; West, CR2
Kim, SH; Rosowsky, A; Ross, J; Wick, MM1
Abraham, TW; Kalman, TI; McIntee, EJ; Wagner, CR1
Zaborowska, D; Zuk, J1
Deguchi, K; Kageyama, S; Komada, F; Minami, N; Morita, K; Nishikawa, M; Shirakawa, S; Uemura, Y1
Higashigawa, M; Hori, H; Kawasaki, H; Ohkubo, T; Sakurai, M; Yoshizumi, T1
Chen, SR; Cuddy, DP; Ross, DD1
Suga, T; Takayama, H; Watanabe, T; Yamada, J; Yoshida, Y1
Arakawa, M; Ekimoto, H; Ishii, T; Kusama, K; Nagahata, T; Shibasaki, C; Takahashi, K; Uchida, T1
Kodama, K; Kuninaka, A; Morozumi, M; Saitoh, K; Saneyoshi, M; Yoshino, H1
Haynes, RH; Kunz, BA; McIntosh, EM1
Rooze, M1
Campbell, J; Mayhew, E; Rustum, YM; Szoka, F1
Myers-Robfogel, MW; Spataro, AC1
Harrington, C; Perrino, FW1
Arie, Y; Hirai, M; Kikukawa, M; Kodo, H; Kumakawa, T; Mizutani, R; Mori, M; Murai, Y; Nakamura, N; Tsutsumi, H1
Braess, J; Hiddemann, W; Kaufmann, C; Ramsauer, B; Schleyer, E; Schüssler, M; Unterhalt, M; Wilde, S1
Niitsu, N; Shikoshi, K; Takada, M; Umeda, M1
Tsukagoshi, S1
Ito, T; Konishi, H; Maesako, Y; Mori, S; Ueda, Y; Yagiri, Y1
Braess, J; Freund, M; Hanauske, A; Heil, G; Hiddemann, W; Kaufmann, C; Kern, W; Schleyer, E; Schüssler, M1
Harvey, S; Mazur, DJ; Perrino, FW; Ward, H1
Berger, U; Hehlmann, R; Hochhaus, A; Kuhn, C; Reiter, A1
Leen, R; van Gennip, AH; van Kuilenburg, AB; Verschuur, AC; Voûte, PA1
Capasso, JM; Hirschberg, CB2

Reviews

2 review(s) available for cytidine monophosphate and cytarabine

ArticleYear
[Recent development of antitumor antimetabolites in Japan--cytosine arabinoside analogues].
    Gan to kagaku ryoho. Cancer & chemotherapy, 1997, Volume: 24, Issue:7

    Topics: Animals; Antimetabolites, Antineoplastic; Arabinonucleotides; Carcinoma, Non-Small-Cell Lung; Clinical Trials, Phase I as Topic; Clinical Trials, Phase II as Topic; Cytarabine; Cytidine Monophosphate; Deoxycytidine; Gemcitabine; Humans; Lung Neoplasms; Mice; Neoplasm Transplantation

1997
AraC-based pharmacotherapy of chronic myeloid leukaemia.
    Expert opinion on pharmacotherapy, 2001, Volume: 2, Issue:7

    Topics: Aged; Antimetabolites, Antineoplastic; Antineoplastic Combined Chemotherapy Protocols; Arabinonucleotides; Clinical Trials as Topic; Cytarabine; Cytidine Monophosphate; Drug Administration Schedule; Guidelines as Topic; Humans; Interferons; Leukemia, Myelogenous, Chronic, BCR-ABL Positive; Survival Analysis

2001

Trials

3 trial(s) available for cytidine monophosphate and cytarabine

ArticleYear
Pharmacokinetics of Ara-CMP-Stearate (YNK01): phase I study of the oral Ara-C derivative.
    Leukemia, 1995, Volume: 9, Issue:6

    Topics: Administration, Oral; Antineoplastic Agents; Arabinofuranosyluracil; Arabinonucleotides; Cytarabine; Cytidine Monophosphate; Dose-Response Relationship, Drug; Half-Life; Humans; Leukemia, Myeloid, Acute; Lymphoma, Non-Hodgkin; Statistics, Nonparametric

1995
[A pharmacokinetic study of the value of oral cytarabine ocfosfate in the treatment of hematological malignancies].
    [Rinsho ketsueki] The Japanese journal of clinical hematology, 1998, Volume: 39, Issue:5

    Topics: Administration, Oral; Aged; Antineoplastic Agents; Arabinonucleotides; Cytarabine; Cytidine Monophosphate; Female; Humans; Leukemia, Myeloid, Acute; Male; Middle Aged; Myelodysplastic Syndromes; Time Factors

1998
Oral cytarabine ocfosfate in acute myeloid leukemia and non-Hodgkin's lymphoma--phase I/II studies and pharmacokinetics.
    Leukemia, 1998, Volume: 12, Issue:10

    Topics: Acute Disease; Administration, Oral; Adult; Antineoplastic Agents; Arabinonucleotides; Biological Availability; Cytarabine; Cytidine Monophosphate; Diarrhea; Dose-Response Relationship, Drug; Half-Life; Humans; Infusions, Intravenous; Leukemia, Myeloid; Lymphoma, Non-Hodgkin; Metabolic Clearance Rate; Prodrugs; Regression Analysis

1998

Other Studies

23 other study(ies) available for cytidine monophosphate and cytarabine

ArticleYear
Additional nucleotide derivatives of mitosenes. Synthesis and activity against parental and multidrug resistant L1210 leukemia.
    Journal of medicinal chemistry, 1991, Volume: 34, Issue:7

    Topics: Animals; Antineoplastic Agents; Cell Line; Chemical Phenomena; Chemistry; Leukemia L1210; Mice; Mitomycin; Mitomycins; Nucleotides

1991
Nucleoside conjugates. 6. Synthesis and comparison of antitumor activity of 1-beta-D-arabinofuranosylcytosine conjugates of corticosteroids and selected lipophilic alcohols.
    Journal of medicinal chemistry, 1985, Volume: 28, Issue:2

    Topics: Adrenal Cortex Hormones; Animals; Antineoplastic Agents; Arabinonucleotides; Cytidine Deaminase; Esters; Female; Humans; Leukemia L1210; Male; Mice

1985
Lipophilic 5'-(alkyl phosphate) esters of 1-beta-D-arabinofuranosylcytosine and its N4-acyl and 2,2'-anhydro-3'-O-acyl derivatives as potential prodrugs.
    Journal of medicinal chemistry, 1982, Volume: 25, Issue:2

    Topics: Animals; Antineoplastic Agents; Chemical Phenomena; Chemistry; Cytarabine; Drug Resistance; Esters; Hydrolysis; Leukemia L1210; Melanoma; Mice; Neoplasms, Experimental

1982
Synthesis and biological activity of aromatic amino acid phosphoramidates of 5-fluoro-2'-deoxyuridine and 1-beta-arabinofuranosylcytosine: evidence of phosphoramidase activity.
    Journal of medicinal chemistry, 1996, Nov-08, Volume: 39, Issue:23

    Topics: Animals; Cell Division; Cell Line; Cytarabine; Floxuridine; Humans; Magnetic Resonance Spectroscopy; Mice; Organophosphorus Compounds; Phosphoric Monoester Hydrolases; Thymidylate Synthase; Tumor Cells, Cultured

1996
The effect of DNA replication on mutation of the Saccharomyces cerevisiae CDC8 gene.
    Current genetics, 1990, Volume: 17, Issue:4

    Topics: Arabinonucleotides; Buffers; Caffeine; Cycloheximide; Cytarabine; Cytidine Monophosphate; DNA Replication; DNA, Fungal; Genes, Fungal; Hydroxyurea; Mutation; Phenotype; Phosphates; Saccharomyces cerevisiae; Ultraviolet Rays

1990
[A case of complete remission from acute unclassified leukemia achieved by using a prodrug of ara C, stearyl-ara-CMP (YNK01)].
    Gan no rinsho. Japan journal of cancer clinics, 1990, Volume: 36, Issue:12

    Topics: Acute Disease; Administration, Oral; Antineoplastic Agents; Arabinonucleotides; Cytarabine; Cytidine Monophosphate; Drug Administration Schedule; Female; Humans; Leukemia; Middle Aged; Prodrugs; Remission Induction

1990
Deoxyribonucleoside triphosphate pools and Ara-CTP levels in P388 murine leukemic cells treated with 1-B-D-arabinofuranosylcytosine-5'-stearylphosphate which is a newly synthesized derivative of 1-B-D-arabinofuranosylcytosine.
    Medical oncology and tumor pharmacotherapy, 1990, Volume: 7, Issue:4

    Topics: Administration, Oral; Animals; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Arabinofuranosylcytosine Triphosphate; Arabinonucleotides; Chromatography, High Pressure Liquid; Cytarabine; Cytidine Monophosphate; Deoxyribonucleotides; Leukemia P388; Male; Mice

1990
Effects of 1-beta-D-arabinofuranosylcytosine on DNA replication intermediates monitored by pH-step alkaline elution.
    Cancer research, 1990, May-01, Volume: 50, Issue:9

    Topics: Arabinonucleotides; Cytarabine; Cytidine Monophosphate; DNA Replication; DNA, Neoplasm; Humans; Hydrogen-Ion Concentration; Kinetics; Leukemia, Promyelocytic, Acute; Thymidine; Tumor Cells, Cultured

1990
Participation of the peroxisomal beta-oxidation system in the chain-shortening of PCA16, a metabolite of the cytosine arabinoside prodrug, YNKO1, in rat liver.
    Biochemical pharmacology, 1990, May-15, Volume: 39, Issue:10

    Topics: Animals; Arabinonucleotides; Cells, Cultured; Clofibrate; Coenzyme A Ligases; Cytarabine; Cytidine Monophosphate; Cytosine Nucleotides; Hydrogen Peroxide; Ketone Bodies; Liver; Microbodies; Mitochondria, Liver; Palmitates; Prodrugs; Rats; Rats, Inbred Strains; Repressor Proteins; Saccharomyces cerevisiae Proteins

1990
[Antitumor activity of a novel analog of cytarabine, 4-amino-1-beta-D-arabinofuranosyl-2(1H)-pyrimidinone 5'-(sodium octadecyl phosphate) monohydrate (YNK01)].
    Gan to kagaku ryoho. Cancer & chemotherapy, 1990, Volume: 17, Issue:8 Pt 1

    Topics: Administration, Oral; Animals; Antineoplastic Agents; Arabinonucleotides; Cytarabine; Cytidine Monophosphate; Cytosine Nucleotides; Drug Administration Schedule; Drug Screening Assays, Antitumor; Female; Injections, Intraperitoneal; Injections, Intravenous; Leukemia L1210; Male; Mice; Neoplasms, Experimental; Tumor Cells, Cultured

1990
Antitumor activity and pharmacology of 1-beta-D-arabinofuranosylcytosine-5'-stearylphosphate: an orally active derivative of 1-beta-D-arabinofuranosylcytosine.
    Japanese journal of cancer research : Gann, 1989, Volume: 80, Issue:7

    Topics: Administration, Oral; Animals; Antineoplastic Agents; Arabinonucleotides; Cytarabine; Cytidine Monophosphate; Cytosine Nucleotides; Drug Administration Schedule; Leukemia L1210; Metabolic Clearance Rate; Mice; Solubility; Structure-Activity Relationship

1989
Inhibition of DNA replication in Saccharomyces cerevisiae by araCMP.
    Current genetics, 1986, Volume: 10, Issue:8

    Topics: Arabinonucleotides; Biological Transport; Cell Division; Chromatography, High Pressure Liquid; Cytarabine; Cytidine Monophosphate; Cytosine Nucleotides; DNA Replication; DNA, Fungal; Mitosis; Recombination, Genetic; Saccharomyces cerevisiae; Thymine Nucleotides

1986
1-beta-D-arabinofuranosylcytosine conjugates of thioether phospholipids as a new class of potential antitumor drugs.
    Cancer drug delivery, 1986,Spring, Volume: 3, Issue:2

    Topics: Animals; Antineoplastic Agents; Arabinonucleotides; Cytarabine; Cytidine Monophosphate; Leukemia L1210; Leukemia P388; Leukemia, Experimental; Male; Mice; Mice, Inbred DBA; Structure-Activity Relationship

1986
Correlations between necrotic patterns and limb skeletal defects induced by antimitotic drugs in the mouse.
    Progress in clinical and biological research, 1983, Volume: 110 Pt A

    Topics: Abnormalities, Drug-Induced; Animals; Antibiotics, Antineoplastic; Cell Survival; Cytarabine; Cytidine Monophosphate; Ectoderm; Extremities; Female; Glycine; Hyperplasia; Limb Deformities, Congenital; Mesoderm; Mice; Mitosis; Necrosis; Pregnancy; Time Factors

1983
Inability of liposome encapsulated 1-beta-D-arabinofuranosylcytosine nucleotides to overcome drug resistance in L1210 cells.
    European journal of cancer & clinical oncology, 1981, Volume: 17, Issue:7

    Topics: Animals; Arabinofuranosylcytosine Triphosphate; Arabinonucleotides; Cells, Cultured; Cytarabine; Cytidine Monophosphate; DNA, Neoplasm; Drug Resistance; Female; Leukemia L1210; Liposomes; Mice; Mice, Inbred DBA

1981
1-beta-D-arabinofuranosylcytosine nucleotide inhibition of sialic acid metabolism in WI-38 cells.
    Cancer research, 1980, Volume: 40, Issue:6

    Topics: Arabinofuranosylcytosine Triphosphate; Arabinonucleotides; Cell Line; Cells, Cultured; Cytarabine; Cytidine Monophosphate; Cytosine Nucleotides; Humans; Sialic Acids; Sialyltransferases; Transferases

1980
The effects of cytosine arabinoside on RNA-primed DNA synthesis by DNA polymerase alpha-primase.
    The Journal of biological chemistry, 1995, Nov-03, Volume: 270, Issue:44

    Topics: Arabinonucleotides; Base Sequence; Cytarabine; Cytidine Monophosphate; DNA Primase; DNA Primers; DNA Replication; Kinetics; Molecular Sequence Data; RNA Nucleotidyltransferases; Templates, Genetic

1995
[Plasma concentration of cytosine arabinoside (Ara-C) in the elderly patients with hematological malignancy treated by Ara-C or cytarabine ocfosfate (SPAC)].
    Nihon Ronen Igakkai zasshi. Japanese journal of geriatrics, 1995, Volume: 32, Issue:3

    Topics: Administration, Oral; Aged; Aged, 80 and over; Antineoplastic Agents; Arabinonucleotides; Cytarabine; Cytidine Monophosphate; Female; Humans; Infusions, Intravenous; Injections, Subcutaneous; Leukemia, Myeloid, Acute; Male; Myelodysplastic Syndromes

1995
[Therapy-related acute non-lymphocytic leukemia (M2) with 7;11 chromosome translocation induced into complete remission by low dose cytosine arabinoside and cytarabine ocfosfate therapy].
    Nihon Ronen Igakkai zasshi. Japanese journal of geriatrics, 1994, Volume: 31, Issue:6

    Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Arabinonucleotides; Chromosomes, Human, Pair 11; Chromosomes, Human, Pair 7; Cytarabine; Cytidine Monophosphate; Female; Humans; Leukemia, Myeloid, Acute; Neoplasms, Second Primary; Remission Induction; Translocation, Genetic

1994
Exonucleases and the incorporation of aranucleotides into DNA.
    Cell biochemistry and biophysics, 1999, Volume: 30, Issue:3

    Topics: Animals; Cattle; Chromatography; Cytarabine; Cytidine Monophosphate; DNA; DNA Polymerase gamma; DNA Repair; DNA Replication; DNA-Directed DNA Polymerase; Electrophoresis, Polyacrylamide Gel; Exodeoxyribonucleases; HL-60 Cells; Humans; Kinetics; Leukemia; Recombinant Proteins; Thymus Gland; Time Factors; Tissue Inhibitor of Metalloproteinases

1999
Cyclopentenyl cytosine increases the phosphorylation and incorporation into dna of arabinofu-ranosyl cytosine in a myeloid leukemic cell-line.
    Advances in experimental medicine and biology, 2000, Volume: 486

    Topics: Antimetabolites, Antineoplastic; Antineoplastic Agents; Carbon-Nitrogen Ligases; Cytarabine; Cytidine; Cytidine Diphosphate; Cytidine Monophosphate; Deoxycytosine Nucleotides; DNA; Dose-Response Relationship, Drug; Enzyme Inhibitors; HL-60 Cells; Humans; Leukemia, Myeloid; Phosphorylation

2000
Mechanisms of glycosylation and sulfation in the Golgi apparatus: evidence for nucleotide sugar/nucleoside monophosphate and nucleotide sulfate/nucleoside monophosphate antiports in the Golgi apparatus membrane.
    Proceedings of the National Academy of Sciences of the United States of America, 1984, Volume: 81, Issue:22

    Topics: Adenine Nucleotides; Adenosine Monophosphate; Animals; Biological Transport; Cytidine Monophosphate; Cytidine Monophosphate N-Acetylneuraminic Acid; Golgi Apparatus; Guanosine Diphosphate Fucose; Guanosine Monophosphate; Nucleoside Diphosphate Sugars; Phosphoadenosine Phosphosulfate; Rats; Sialic Acids

1984
Effect of nucleotides on translocation of sugar nucleotides and adenosine 3'-phosphate 5'-phosphosulfate into Golgi apparatus vesicles.
    Biochimica et biophysica acta, 1984, Oct-17, Volume: 777, Issue:1

    Topics: Adenine Nucleotides; Animals; Binding, Competitive; Biological Transport; Cytidine Monophosphate; Cytidine Monophosphate N-Acetylneuraminic Acid; Golgi Apparatus; Guanine Nucleotides; Guanosine Diphosphate Fucose; Liver; Nucleoside Diphosphate Sugars; Nucleotides; Phosphoadenosine Phosphosulfate; Rats; Sialic Acids; Structure-Activity Relationship; Uridine Monophosphate

1984