cytidine diphosphate choline has been researched along with choline in 281 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 197 (70.11) | 18.7374 |
| 1990's | 38 (13.52) | 18.2507 |
| 2000's | 21 (7.47) | 29.6817 |
| 2010's | 15 (5.34) | 24.3611 |
| 2020's | 10 (3.56) | 2.80 |
| Authors | Studies |
|---|---|
| Bean, B; Tomasz, A | 1 |
| Leak, DJ; Poxton, IR | 1 |
| Fonlupt, P; Martinet, M; Pacheco, H | 3 |
| Bellati, U; Bracaglia, R; Garzetti, GG; Serri, F | 1 |
| Boismare, F; Le Poncin-Lafitte, M; Rapin, JR | 1 |
| Boismare, F; Le Poncin-Lafitte, M | 1 |
| Cohadon, F; Guérin, B; Rigoulet, M; Vandendriessche, M | 1 |
| Akesson, B; Sundler, R | 2 |
| Bygrave, FL; Dawson, RM | 1 |
| Kennard, O; Post, ML; Seshadri, TP; Viswamitra, MA | 1 |
| Ishii, K; Nakamura, K; Yamada, N; Zeze, F | 1 |
| Galeone, F; Guarguaglini, M; Saba, P; Salvadorini, F | 1 |
| Okuda, K; Takamatsu, M; Yashima, K | 1 |
| Lauzon, GJ; Paran, JH; Paterson, AR | 1 |
| Belch, AW; Lauzon, GJ; Paterson, AR | 1 |
| Esplugues, J; Marco, J; Martí Viaño, JL; Orts, A; Sellés, J; Vega, F | 1 |
| Cantore, ML; De Recondo, ME; Fecondo, EF | 1 |
| Ciarimboli, M; Di Grezia, F; Lingetti, E; Lingetti, M; Policicchio, D; Policicchio, F | 1 |
| Bellati, U; Bracaglia, R; Buscemi, L; Garzetti, GG; Liverani, A; Riccardi, P | 1 |
| Armeli, G; De Gregorio, G; Francolino, A; Restivo, S | 1 |
| Kawanaka, M; Matsuoka, T; Nagai, K | 1 |
| Boismare, F; Le Poncin, M; Lecordier, JC; Lefrançois, J | 1 |
| Cubells, JM; De Blas, A; Hernando, C | 1 |
| Kimura, A | 1 |
| Agnoli, A; Casacchia, M; Ruggieri, S; Zamponi, A | 1 |
| Broad, TE; Dawson, RM | 1 |
| Galeone, F; Nicotera, M; Ombrato, M; Saba, P; Salvadorini, F | 1 |
| Cornia, G; Gramiccioni, E | 2 |
| Francescangeli, E; Goracci, G; Mozzi, R; Piccinin, GL; Porcellati, G; Woelk, H | 1 |
| Dodd, RC; Havener, LJ; Spargo, BH; Toback, FG | 1 |
| Kuksis, A; O'Doherty, PJ; Smith, NB | 1 |
| Calsini, P; Del Soldato, P; Papeschi, G; Sesti, AG | 1 |
| Arienti, G; Corazzi, L; Porcellati, G; Woelk, H | 1 |
| Gilder, H; McSherry, CK | 1 |
| Ogashiwa, M; Takeuchi, K | 1 |
| Collins, FD; Shamgar, FA | 1 |
| Colombo, ML; Dogliani, P; Raggi, M | 1 |
| Abe, H; Kawaguchi, Y; Masu, K; Takahashi, M; Tanji, H | 1 |
| Kono, S; Mitsunobu, K; Nakashima, Y; Otsuki, S; Watanabe, S | 1 |
| Beeler, DA; Korniat, EK | 1 |
| Kawaguchi, N; Kitane, Y; Nojima, T; Saito, Y | 1 |
| Hara, M; Ogashiwa, M; Okada, J; Takeuchi, K; Tanaka, Y | 1 |
| Hirose, K; Kariya, Y; Kimura, A; Nagai, S | 1 |
| Cook, GA; Daron, HH; Perry, WD | 1 |
| Choy, PC; Jay, FT; Zha, X | 1 |
| Chan, M; Choy, PC; Hatch, G; Man, RY | 1 |
| Abbiati, G; Acuto, G; Barzaghi, N; Fossati, T; Gatti, G; Perucca, E | 1 |
| Arevalo, JI; Saz, HJ | 1 |
| Byers, DM; Cook, HW; George, TP; Palmer, FB; Spence, MW | 1 |
| Petkov, VD; Petkov, VV; Stancheva, SL; Tocuschieva, L | 1 |
| Kent, C; Taparowsky, EJ; Teegarden, D | 1 |
| Bernardi, M; Diaspri, GP; Gasbarrini, A; Gasbarrini, G; Giancane, S; Rimondi, A; Sakellaridis, E; Serra, F; Tamè, MR | 1 |
| Cervós-Navarro, J; Hamdorf, G | 1 |
| Graschew, G; Hull, WE; Kuesel, AC; Lorenz, W; Thielmann, HW | 1 |
| Mosharrof, AH; Petkov, VD | 1 |
| Cervós-Navarro, J; Lafuente, JV | 1 |
| Getova, D; Petkov, V | 1 |
| Adachi, H; Aoki, E; Honda, T; Noguchi, M; Ohnishi, S; Sato, S; Torizuka, K | 1 |
| Barr, HA; Nicholas, TE; Power, JH | 1 |
| Dani, HM; Misra, UK; Narayan, S | 1 |
| Auteri, A; Bianciardi, G; Fabrini, P; Resi, L; Salvi, M; Tanganelli, P; Toti, P; Weber, G | 1 |
| Covelli, G; De Gregorio, F; Grechi, G; Pecori Giraldi, J; Virno, M | 1 |
| Byers, DM; Cook, HW; George, TP; Morash, SC; Palmer, FB; Spence, MW | 1 |
| Dworkin, J; Mar, A; Oró, J | 1 |
| Arrigoni, E; Averet, N; Cohadon, F | 1 |
| Hoffman, JM; Laychock, SG | 1 |
| Martin, TW; Michaelis, KC | 1 |
| Arena, M; Campo, G; Grasso, A; Sofia, V; Ventimiglia, A | 1 |
| Clandinin, MT; Hargreaves, KM | 1 |
| Capobianco, G; Palleschi, M | 1 |
| Jaffe, JJ; Srivastava, AK | 1 |
| Dabrowiecki, Z; Dorman, RV; Goldberg, WJ; Horrocks, LA | 1 |
| Infante, JP | 1 |
| Jarrige, B; Raggueneau, JL | 1 |
| Cubells, JM; Hernando, C | 1 |
| Dreyfus, H; Freysz, L; Golly, F; Massarelli, R; Mykita, S | 1 |
| Boismare, F; Daoust, M; Moore, N; Saligaut, C | 2 |
| Petkov, VD; Popova, JS | 1 |
| Mosharrof, AH; Petkov, VD; Petkov, VV | 2 |
| Damron, DS; Dorman, RV | 1 |
| Sanjurjo, P; Valls i Soler, A; Vázquez Cordero, C | 1 |
| Fujishima, M; Kameyama, M; Kutsuzawa, T; Omae, T; Otomo, E; Sakai, F; Sakuma, A; Tazaki, Y | 1 |
| Bloch, K; Chin, J | 1 |
| Fukuda, N; Kakihana, M; Nagaoka, A; Suno, M | 1 |
| Choy, PC; Hatch, GM; Stevens, WK | 1 |
| Choy, PC; Man, RY; Wientzek, M | 1 |
| Besterman, JM; Cuatrecasas, P; Duronio, V | 1 |
| Gualtieri, S; Pacchetti, C; Sinforiani, E; Trucco, M | 1 |
| Galli, C; Giani, E; Masi, I | 1 |
| Fieldsend, JK; Higgins, JA | 1 |
| Ancelin, ML; Capron, A; Torpier, G; Vial, HJ | 1 |
| Aguirre de Cárcer, A; Juárez Ucelay, F; Marcos Sánchez, F; Moreiras Jiménez, JL | 1 |
| Calicchio, G; Centrone, G; Ragno, G | 1 |
| Bonavita, E | 1 |
| Agut, J; Coviella, G; Lopez, I; Wurtman, RJ | 1 |
| Cornell, R; Lim, P; Vance, DE | 1 |
| Duterte, D; Lageron, A; Le Poncin-Lafitte, M; Rapin, JR | 1 |
| Combe, J; Combe, M; Neidhardt, A; Schipmann, N | 1 |
| Chander, A; Dodia, C; Fisher, AB; Yost, RW | 1 |
| Fouilland, L; Gagniarre, J; Lecerf, J | 1 |
| Biot, N; Brune, J; Douss, T; Pacheco, Y; Perrin-Fayolle, M; Pujol, B; Revol, A; Vergnon, JM | 1 |
| Baso, G; Crolle, G; Cucca, S; Gosparini, B; Martechini, A; Urbani, N; Vattolo, S | 1 |
| Ambrosi, R; Briolini, F; Losapio, GM; Nespoli, M; Setti, M; Terraneo, F | 1 |
| Boismare, F; Chadelaud, M; Chretien, P; Daoust, M; Moore, N; Saligaut, C | 1 |
| Binaglia, L; Dreyfus, H; Freysz, L; Golly, F; Massarelli, R; Porcellati, G | 1 |
| Miyazaki, M | 1 |
| Berchicci, R; Cuzzoni, G; Merchan, C; Pecorini, M | 1 |
| Concas, A; Porceddu, ML | 1 |
| Cighetti, G; Del Puppo, M; Kienle, MG; Paroni, R | 1 |
| De Rosa, M; del Piano, L; Galletti, P; Nappi, MA; Pontoni, G; Salluzzo, A; Zappia, V | 1 |
| Melnykovych, G; Standaert, MM | 1 |
| Hashihira, S; Mori, R; Nishii, T; Tai, J; Takeda, Y | 1 |
| Adler, M; Cantoni, GL; Chiang, PK; de Blas, A; Nirenberg, M; Shih, M | 1 |
| Alberghina, M; Giuffrida, AM; Mistretta, A; Serra, I; Viola, M | 2 |
| Dunier, M; Luffau, G; Mecheri, S; Paraf, A; Pery, P; Singh, SN | 1 |
| Aguilar, J; Agut, J; Bachs, O; Enrich, C; Giménez, R | 1 |
| Paddon, HB; Trip, EM; Vance, DE | 1 |
| Kent, C; Sleight, R | 1 |
| Esko, JD; Raetz, CR | 1 |
| Naito, H; Yasuhara, M | 1 |
| Paddon, HB; Vance, DE | 1 |
| Kanoh, H; Ohno, K | 1 |
| Brooks, RL; Feldman, DA; Miller, JC; Quade, MM; Weinhold, PA | 1 |
| Kumagai, A; Matsuoka, N; Saito, Y; Sasaki, N; Shirai, K | 1 |
| Benzi, G; Curti, D; Polgatti, M; Villa, RF | 1 |
| Nikawa, J; Yamashita, S; Yonemura, K | 1 |
| Harwood, JL; Price-Jones, MJ | 1 |
| Angle, CR; Markin, RS; Stohs, SJ; Swanson, MS | 1 |
| Akamatsu, Y; Kuge, O; Maeda, M; Nakano, A; Nishijima, M | 1 |
| Jenden, DJ; Paglia, DE; Valentine, WN | 1 |
| Pelech, SL; Percival-Smith, A; Pritchard, PH; Sommerman, EF; Vance, DE | 1 |
| Aylward, M; Castelló, J; Dinsdale, JR; Griffiths, GK; Maddock, J; Ortiz, JA; Rowlands, C | 1 |
| O'Doherty, PJ | 1 |
| Batenburg, JJ; Post, M; Smith, BT; Van Golde, LM | 1 |
| Kosaka, A | 1 |
| Lachant, NA; Tanaka, KR | 1 |
| Agut, J; Coviella, IL; Wurtman, RJ | 1 |
| Nakatani, M; Paglia, DE; Rauth, BJ; Valentine, WN | 1 |
| Castelló, J; Fernández, JM; Forné, E; Ortíz, JA; Sacristán, A; Sánchez, MC | 1 |
| Algate, DR; Beard, DJ; Davies, JE; Ortiz, JA; Sacristán, A | 1 |
| Agut, J; Font, E; Ortiz, JA; Sacristán, A | 4 |
| Ortiz, JA; Sacristán, A; Tornos, ME | 3 |
| Grau, T; Ortiz, JA; Romero, A; Sacristán, A | 4 |
| Brasó, MA; Ortiz, JA; Sacristán, A | 1 |
| Ortiz, JA; Romero, A; Sacristán, A; Serratosa, J | 3 |
| Aylward, M; Castelló, J; Dinsdale, JR; Griffiths, GK; Maddock, J; Ortiz, JA | 1 |
| Arranz, J; Ganoza, C | 1 |
| Lozano Fernández, R | 1 |
| De Medio, GE; Piccinin, GL; Porcellati, G; Trovarelli, G | 1 |
| Floridi, A; Palmerini, CA; Piccinin, GL; Porcellati, G; Trovarelli, G | 1 |
| Choy, PC; Zelinski, TA | 1 |
| Arena, M; Bizzarro, G; Campo, G; Corso, EA; Rodolico, F; Ventimiglia, A | 1 |
| Ayuso-Gutierrez, JL; Saiz-Ruiz, J | 1 |
| Cascales, C; Cascales, M; Santos-Ruiz, A; Santos-Ruiz, MR | 1 |
| Chiccoli, A; Galluzzi, F; La Cauza, C; Nania, C; Salti, R; Seminara, S | 1 |
| Cohadon, F; Poletto, B; Richer, E | 1 |
| Aiello, A; de Rosa, E; de Rosa, G; Gulino, A; Makhoul, O; Pasargiklian, E; Satta, MA | 1 |
| Matsunaga, T; Okumura, SI | 1 |
| de Medio, GE; Dorman, RV; Horrocks, LA; Piccinin, GL; Porcellati, G; Trovarelli, G | 1 |
| Scillieri, E; Stramba-Badiale, M | 1 |
| Dabrowiecki, Z; Dorman, RV; Horrocks, LA | 1 |
| Binaglia, L; Floridi, A; Palmerini, CA; Procellati, G; Vecchini, A | 1 |
| Hasegawa, T; Hazama, T; Sakuma, A; Ueda, S | 1 |
| Choy, PC; Man, RY; Savard, JD; Zelinski, TA | 1 |
| Faryna de Raveglia, IA; Pasquini, JM; Soto, EF | 1 |
| Cocchiara, G; De Rosa, M; Romeo, G; Zappia, V | 1 |
| Cantoni, GL; Chiang, PK; Pritchard, PH; Vance, DE | 1 |
| Agnoli, A; Arrigoni, E; Benzi, G; Dossena, M; Giuffrida, AM; Pastoris, O; Villa, RF | 1 |
| Podesta, RB; Young, BW | 1 |
| Kennedy, EP; Voelker, DR | 1 |
| Choy, PC | 1 |
| Batenburg, JJ; Post, M; Schuurmans, EA; Van Golde, LM | 1 |
| De Medio, GE; Montanini, I; Trovarelli, G | 1 |
| Agnoli, A; Bruno, G; Denaro, A; Ruggieri, S | 1 |
| Cattani, P; Maffetti, G; Zanoio, L; Zardini, E | 1 |
| Haines, DS; Possmayer, F; Tokmakjian, S | 1 |
| Casola, PG; Chan, F; Harding, PG; MacDonald, P; Ormseth, MA; Possmayer, F; Tokmakjian, S; Wong, T | 1 |
| Fujiwara, M; Hidaka, H; Kageyama, N; Shibuya, M; Taniguchi, T | 1 |
| Cocchiara, G; De Rosa, M; Giordano, F; Romeo, G; Zappia, V | 1 |
| Andreana, A; Cocchiara, G; De Rosa, M; Romeo, G; Ruggiero, G; Zappia, V | 1 |
| Possmayer, F; Tokmakjian, S | 1 |
| Stanzani, S | 1 |
| Alberghina, M; Giuffrida, AM; Viola, M | 1 |
| Dabrowiecki, Z; Dorman, RV; Goracci, G; Horrocks, LA; Porcellati, G | 1 |
| Capitman, N; Faryna de Raveglia, I; Pasquini, JM; Soto, EF | 1 |
| Canino, V; Segre, D | 1 |
| Forli, C; Galeone, F; Saba, P; Salvadorini, F; Tusini, G | 1 |
| Grossmann, G; Lachmann, B; Malmqvist, E; Nilsson, R; Robertson, B | 1 |
| Bussière, M; Campenot, RB; Ure, DR; Vance, DE; Vance, JE | 1 |
| Agut, J; López-Coviella, I; Ortiz, JA; Savci, V; Wurtman, RJ | 1 |
| Boggs, KP; Jackowski, S; Rock, CO | 1 |
| Bankaitis, VA; Bell, RM; Fry, MR; McGee, TP; McMaster, CR; Skinner, HB | 1 |
| Bankaitis, VA; McGee, TP; Skinner, HB | 1 |
| Bindra, A; Khuller, GK | 1 |
| Bell, RM; McMaster, CR | 1 |
| Hatch, GM; Oskin, A; Vance, DE | 1 |
| Bussière, M; Campenot, RB; Pan, D; Vance, DE; Vance, JE | 1 |
| Rabkin, SW | 1 |
| Burdge, GC; Kelly, FJ; Postle, AD | 1 |
| Choy, PC; Man, RY; Tran, K | 1 |
| Cui, Z; Houweling, M; Vance, DE | 1 |
| Hochanadel, GS; Lieberman, HR; Myers, D; Spiers, PA; Wurtman, RJ | 1 |
| Le Grimellec, C; Leroy, C; Moll, G; Zlatkine, P | 1 |
| Appelmans, KE; Babb, SM; Cohen, BM; Renshaw, PF; Wurtman, RJ | 1 |
| Bakovic, M; Lee, MW; Vance, DE | 1 |
| Fujio, T; Maruyama, A | 1 |
| Boggs, K; Jackowski, S; Rock, CO | 1 |
| Kummerow, FA; Zhou, Q | 1 |
| Coleman, RA; Igal, RA | 1 |
| Favre, G; Miquel, K; Pradines, A; Selmi, S; Tercé, F | 1 |
| Burdge, GC; Hunt, AN | 1 |
| Bruland, O; Holmsen, H; Lillehaug, JR; Thorsen, VA | 1 |
| Anthony, ML; Brindle, KM; Zhao, M | 1 |
| DeGregorio-Rocasolano, N; Gasull, T; Trullas, R; Zapata, A | 1 |
| Regan, M; Ulus, I; Wurtman, RJ; Yu, L | 1 |
| Angelogianni, P; Plataras, C; Tsakiris, S | 1 |
| Blusztajn, JK; Farber, SA; Slack, BE | 1 |
| Antony, P; Freysz, L; Kanfer, JN | 1 |
| Ben-Menachem, G; Brenner, T; Mousa, A; Pinto, F; Rottem, S; Zähringer, U | 1 |
| Cavun, S; Goktalay, G; Savci, V; Ulus, IH | 1 |
| Cansev, M; Cavun, S; Goktalay, G; Savci, V; Ulus, IH; Yilmaz, MS | 1 |
| ANSELL, GB; BAYLISS, BJ | 1 |
| PRITCHARD, ET; ROSSITER, RJ; STRICKLAND, KP; SUBRAHMANYAM, D; THOMPSON, W | 1 |
| TANAKAMARU, S | 1 |
| HAYAKAWA, I; MIYAKE, H; TAKAKURA, K | 1 |
| Kulinski, A; Vance, DE; Vance, JE | 1 |
| Ben Mamoun, C; Calas, M; Minca, M; Richier, E; Roggero, R; Vial, H; Zufferey, R | 1 |
| Bergen, HT; Dakshinamurti, S; Giles, BL; Hastings, C; Lombaert, GA; Mantsch, HH; Rand, T; Scott, JE; Shaw, AR; Thliveris, JA | 1 |
| Adibhatla, RM; Hatcher, JF; Tureyen, K | 1 |
| Fernández-Murray, JP; McMaster, CR | 1 |
| Ben Mamoun, C; Witola, WH | 1 |
| Cansev, M; Hamurtekin, E; Ilcol, YO; Ulus, IH; Yilmaz, MS | 4 |
| Coskun, C; Savci, V; Yalcin, M; Yilmaz, MS | 1 |
| Cansev, M; Hamurtekin, E; Ilcol, YO; Isbil-Buyukcoskun, N; Ozluk, K; Ulus, IH | 1 |
| Cansev, M; Ilcol, YO; Ulus, IH; Yilmaz, Z | 1 |
| Cansev, M; Eralp, O; Kocaturk, M; Ozarda, Y; Ulus, IH; Yilmaz, Z | 1 |
| Bernhard, W; Clark, H; Henderson, NG; Koster, G; Postle, AD; Pynn, CJ | 1 |
| Amenta, F; Cerasa, LS; Di Stefano, A; Sozio, P; Tayebati, SK; Tomassoni, D | 1 |
| Aslan, E; Bekar, A; Kocaeli, H; Tolunay, S; Ulus, IH | 1 |
| Bagdas, D; Gurun, MS; Hamurtekin, E; Sonal, S; Sonat, FA | 1 |
| Bekar, A; Caner, B; Cansev, M; Kafa, MI; Karli, N; Kurt, MA; Ulus, IH | 1 |
| Bruce, SE | 1 |
| Dastidar, SG; Ghosh, D; Gupta, B; Haldar, D; Pal, TK; Sarkar, AK; Sarkar, P | 1 |
| Fagone, P; Jackowski, S | 1 |
| Amenta, F; Cerasa, LS; Di Stefano, A; Nwankwo, IE; Sozio, P; Tayebati, SK; Tomassoni, D | 1 |
| Baumgärtner, W; Degen, D; Gold, R; Gropengießer, K; Gudi, V; Hammer, A; Jörg, S; Lee, DH; Linker, RA; Manzel, A; Moharregh-Khiabani, D; Pul, R; Salinas Tejedor, L; Schäfer, N; Singh, V; Skripuletz, T; Stangel, M; Voss, E; Vulinovic, F; Wolf, R | 1 |
| Batistel, F; Loor, JJ; Luchini, DL; Martinez-Cortés, I; Pate, RT; Zhou, YF; Zhou, Z | 1 |
| Phyu, SM; Smith, TAD; Tseng, CC | 1 |
| Chan, KC; Faiq, MA; Schuman, JS; Wollstein, G | 1 |
| Goyal, A; Gupta, JK; Narayan Yadav, H; Qureshi, SS | 1 |
| Cai, M; Liu, H; Liu, Q; Ren, Y; Zhang, Y; Zhou, X | 1 |
| Putilina, MV | 1 |
| Aidelbaum, R; Choueiry, J; Knott, V; Labelle, A | 1 |
| Buturak, A; Cansev, M; Ceron, JJ; Kocaturk, M; Ozarda, Y; Ulus, IH; Yilmaz, Z | 1 |
| Arcadi, FA; Bonanno, L; Bramanti, P; Corallo, F; De Cola, MC; Formica, C; Lo Buono, V; Marino, S; Scarfì, C; Torrisi, M | 1 |
| Afzal, A; Alanazi, MM; Alasmari, F; Alharbi, M; Alqahtani, F; Alsanea, S; Ashraf, W; Farooq, T; Imran, I; Javaid, S; Rasool, MF; Rehman, Z | 1 |
| Arici, MA; Baris, E; Simsek, O; Tosun, M | 1 |
| Kansakar, U; Lombardi, A; Mone, P; Santulli, G; Trimarco, V; Varzideh, F | 1 |
| He, Y; Qian, H; Wang, Z; Yang, M; Yang, Y | 1 |
| Chen, Q; Gao, Y; Guo, L; Jiang, H; Xu, M; Zhang, F; Zhou, F | 1 |
6 review(s) available for cytidine diphosphate choline and choline
| Article | Year |
|---|---|
[Control mechanism in fermentative production of nucleotide coenzymes (author's transl)].
Topics: Adenosine Triphosphate; Choline; Coenzymes; Cytidine Diphosphate Choline; Fermentation; Glucose; Glycolysis; Hexokinase; Methods; Mitochondria; Nucleotides; Phosphates; Protoplasts; Yeasts | 1976 |
[National inquiry on the outcome of severe head injuries: analysis of 921 injured patients treated with CDP-choline].
Topics: Adult; Choline; Craniocerebral Trauma; Cytidine Diphosphate Choline; France; Humans | 1988 |
Phosphatidylcholine and the CDP-choline cycle.
Topics: Animals; Biological Transport; Cell Membrane; Choline; Choline Kinase; Choline-Phosphate Cytidylyltransferase; Cytidine Diphosphate Choline; Diglycerides; Endoplasmic Reticulum; Golgi Apparatus; Isoenzymes; Mice; Mice, Knockout; Phosphatidylcholines; Saccharomyces cerevisiae | 2013 |
Cholinergic nervous system and glaucoma: From basic science to clinical applications.
Topics: Acetylcholine; Choline; Cholinergic Agents; Cytidine Diphosphate Choline; Glaucoma; Humans; Neuroprotective Agents; Retinal Ganglion Cells; Signal Transduction; Visual Cortex | 2019 |
Dynamics of Choline-Containing Phospholipids in Traumatic Brain Injury and Associated Comorbidities.
Topics: Brain; Brain Injuries, Traumatic; Choline; Comorbidity; Cytidine Diphosphate Choline; Humans; Neurodegenerative Diseases; Neuroglia; Oxidative Stress; Phosphatidylcholines; Phospholipids | 2021 |
Choline supplements: An update.
Topics: Acetylcholine; Choline; Cytidine Diphosphate Choline; Dietary Supplements; Glycerylphosphorylcholine | 2023 |
19 trial(s) available for cytidine diphosphate choline and choline
| Article | Year |
|---|---|
[Therapeutic effects of cyticholine (cytidine-diphospho-choline) in Parkinsonian syndrome].
Topics: Adult; Aged; Choline; Clinical Trials as Topic; Cytidine Diphosphate Choline; Drug Evaluation; Female; Humans; Middle Aged; Parkinson Disease, Postencephalitic; Parkinson Disease, Secondary | 1976 |
Clinical evaluation of CDP-choline (Nicholin): efficacy As antidepressant treatment.
Topics: Aged; Antidepressive Agents; Choline; Clinical Trials as Topic; Cytidine Diphosphate Choline; Depression; Drug Evaluation; Female; Growth Hormone; Humans; Male; Middle Aged; Psychiatric Status Rating Scales; Time Factors | 1975 |
A comparative study of free plasma choline levels following intramuscular administration of L-alpha-glycerylphosphorylcholine and citicoline in normal volunteers.
Topics: Adult; Choline; Cytidine Diphosphate Choline; Glycerylphosphorylcholine; Humans; Injections, Intramuscular; Male; Placebos | 1992 |
[Effect of CDP-choline on senile mental deterioration. Multicenter experience on 237 cases].
Topics: Activities of Daily Living; Aged; Aged, 80 and over; Choline; Cytidine Diphosphate Choline; Dementia; Drug Administration Schedule; Drug Evaluation; Female; Humans; Male; Multicenter Studies as Topic | 1990 |
Clinical trial on the use of cytidine diphosphate choline in Parkinson's disease.
Topics: Choline; Clinical Trials as Topic; Cytidine Diphosphate Choline; Dopamine; Female; Humans; Male; Middle Aged; Parkinson Disease; Receptors, Dopamine | 1988 |
[Controlled study of the administration of CDP-choline to preterm newborn infants with respiratory distress syndrome].
Topics: Choline; Cytidine Diphosphate Choline; Double-Blind Method; Humans; Infant, Newborn; Oxygen Inhalation Therapy; Palmitic Acid; Palmitic Acids; Phosphatidylcholines; Prospective Studies; Pulmonary Surfactants; Random Allocation; Respiratory Distress Syndrome, Newborn; Sphingomyelins | 1988 |
Treatment of acute cerebral infarction with a choline precursor in a multicenter double-blind placebo-controlled study.
Topics: Acute Disease; Adult; Aged; Aged, 80 and over; Cerebral Infarction; Choline; Clinical Trials as Topic; Consciousness; Cytidine Diphosphate Choline; Double-Blind Method; Female; Humans; Male; Middle Aged; Prospective Studies; Random Allocation | 1988 |
[Evaluation of the effects of citicoline in chronic cerebrovascular diseases].
Topics: Aged; Cerebrovascular Disorders; Choline; Chronic Disease; Clinical Trials as Topic; Cytidine Diphosphate Choline; Double-Blind Method; Humans; Intracranial Arteriosclerosis; Male; Middle Aged; Psychological Tests; Random Allocation | 1986 |
[Is it possible to improve erythrocyte deformability in vascular diseases in the aged? Preliminary study].
Topics: Age Factors; Aged; Choline; Clinical Trials as Topic; Confusion; Cytidine Diphosphate Choline; Drug Evaluation; Erythrocyte Deformability; Erythrocyte Membrane; Female; Humans; Male; Middle Aged; Vascular Diseases | 1985 |
CDP-choline: repeated oral dose tolerance studies in adult healthy volunteers.
Topics: Adult; Blood Pressure; Choline; Cytidine Diphosphate Choline; Electrocardiography; Electroencephalography; Eye Movements; Female; Humans; Male; Pulse; Pupil; Reflex; Respiration; Time Factors | 1983 |
[CDP choline in cerebral vasculopathy: clinical evaluation and instrumental semeiology].
Topics: Aged; Cerebrovascular Disorders; Choline; Clinical Trials as Topic; Cytidine Diphosphate Choline; Double-Blind Method; Drug Evaluation; Electroencephalography; Evoked Potentials, Somatosensory; Female; Humans; Male; Middle Aged; Placebos | 1982 |
The value of cytidine-5-diphosphate-choline in the prevention of impairment of memory function after electric convulsive therapy. A double-blind study.
Topics: Adult; Choline; Clinical Trials as Topic; Cytidine Diphosphate Choline; Double-Blind Method; Electroconvulsive Therapy; Female; Humans; Male; Memory Disorders; Premedication | 1982 |
[A precursor of phospholipids in the treatment of severe traumatic comas].
Topics: Adult; Aged; Brain Injuries; Choline; Clinical Trials as Topic; Coma; Cytidine Diphosphate Choline; Double-Blind Method; Female; Humans; Male; Middle Aged; Random Allocation; Time Factors | 1982 |
Evaluation of the effect of CDP-choline on poststroke hemiplegia employing a double-blind controlled trial. Assessed by a new rating scale for recovery in hemiplegia.
Topics: Choline; Clinical Trials as Topic; Cytidine Diphosphate Choline; Double-Blind Method; Hemiplegia; Humans; Movement; Physical Therapy Modalities; Placebos | 1980 |
Citicoline improves verbal memory in aging.
Topics: Aged; Aged, 80 and over; Analysis of Variance; Choline; Cross-Over Studies; Cytidine Diphosphate Choline; Double-Blind Method; Female; Humans; Intelligence Tests; Male; Memory; Memory Disorders; Middle Aged; Nootropic Agents; Placebos; Speech | 1996 |
Effect of oral CDP-choline on plasma choline and uridine levels in humans.
Topics: Administration, Oral; Aged; Aged, 80 and over; Animals; Choline; Cytidine; Cytidine Diphosphate Choline; Cytidine Triphosphate; Female; Humans; Male; Middle Aged; Nootropic Agents; PC12 Cells; Rats; Uridine; Uridine Triphosphate | 2000 |
Improvements in quantitative EEG following consumption of a natural citicoline-enhanced beverage.
Topics: Adult; Attention; Beverages; Brain; Choline; Cross-Over Studies; Cytidine Diphosphate Choline; Dietary Supplements; Double-Blind Method; Electroencephalography; Female; Humans; Male; Taurine | 2012 |
A rapid LC-ESI-MS/MS method for the quantitation of choline, an active metabolite of citicoline: Application to in vivo pharmacokinetic and bioequivalence study in Indian healthy male volunteers.
Topics: Administration, Oral; Adult; Choline; Chromatography, High Pressure Liquid; Cross-Over Studies; Cytidine Diphosphate Choline; Delayed-Action Preparations; Humans; Male; Reproducibility of Results; Spectrometry, Mass, Electrospray Ionization; Tablets; Tandem Mass Spectrometry; Therapeutic Equivalency | 2012 |
The acute dose and baseline amplitude-dependent effects of CDP-choline on deviance detection (MMN) in chronic schizophrenia: A pilot study.
Topics: Choline; Cytidine Diphosphate Choline; Electroencephalography; Evoked Potentials; Humans; Pilot Projects; Schizophrenia | 2022 |
256 other study(ies) available for cytidine diphosphate choline and choline
| Article | Year |
|---|---|
Choline metabolism in pneumococci.
Topics: Cell Wall; Choline; Choline Kinase; Cytidine Diphosphate Choline; Nucleotidyltransferases; Phosphorylcholine; Streptococcus pneumoniae; Teichoic Acids | 1977 |
The biosynthesis of a choline nucleotide by a cell-free extract from Streptococcus pneumoniae.
Topics: Cell-Free System; Choline; Choline Kinase; Cytidine Diphosphate Choline; Nucleotidyltransferases; Streptococcus pneumoniae | 1977 |
Interaction of CDP-choline with synaptosomal transport of biogenic amines and their precursors in vitro and in vivo in the rat corpus striatum.
Topics: Animals; Biogenic Amines; Cell-Free System; Choline; Corpus Striatum; Cytidine Diphosphate Choline; Dopamine; Kinetics; Male; Neurotransmitter Agents; Norepinephrine; Rats; Serotonin; Synaptosomes; Tryptophan; Tyrosine | 1978 |
[Study of fetal alveolar surfactant: possibility of induction].
Topics: Adrenergic beta-Agonists; Adult; Choline; Cytidine Diphosphate Choline; Female; Fetus; Glucocorticoids; Humans; Hyaline Membrane Disease; Infant, Newborn; Pregnancy; Pulmonary Alveoli; Pulmonary Surfactants; Respiratory Distress Syndrome, Newborn | 1979 |
[Hemodynamic, functional and biochemical effects of hypobaric hypoxia in rats treated with cytidine diphosphocholine].
Topics: Animals; Avoidance Learning; Blood Pressure; Brain; Choline; Cytidine Diphosphate Choline; Dopamine; Female; Heart Rate; Hypoxia; Norepinephrine; Oxygen; Plethysmography, Impedance; Pressure; Rats | 1978 |
[Effect of citidoline on hemodynamics in the normobaric hypoxic dog].
Topics: Animals; Blood Pressure; Carbon Dioxide; Cardiac Output; Choline; Cytidine Diphosphate Choline; Dogs; Female; Heart Rate; Hypoxia; Male; Oxygen; Partial Pressure; Pressure | 1978 |
[Vasogenic cerebral oedema. Changes in membrane ATPases. Correction by a phospholipid precursor (author's transl)].
Topics: Adenosine Triphosphatases; Animals; Brain Edema; Cell Membrane; Choline; Cytidine Diphosphate Choline; Mitochondria; Phospholipids; Potassium; Rabbits; Sodium | 1979 |
Biosynthesis of phosphatidylethanolamines and phosphatidylcholines from ethanolamine and choline in rat liver.
Topics: Animals; Choline; Cytidine Diphosphate Choline; Diacylglycerol Cholinephosphotransferase; Ethanolamines; Haplorhini; Kinetics; Liver; Male; Models, Biological; Phosphatidylcholines; Phosphatidylethanolamines; Phospholipids | 1975 |
Phosphatidylcholine biosynthesis in the anaerobic protozoon Entodinium caudatum.
Topics: Anaerobiosis; Animals; Cell Membrane; Choline; Cytidine Diphosphate Choline; Enzyme Activation; Eukaryota; Magnesium; Organophosphorus Compounds; Phosphatidylcholines; Phosphotransferases | 1975 |
Molecular structures of cytidine-5'-diphosphate and cytidine-5'-diphospho-choline, and their role in intermidiary metabolism.
Topics: Choline; Cytidine Diphosphate Choline; Cytosine Nucleotides; Diphosphates; Models, Molecular | 1975 |
[Therapeutic effects of CDP-choline and premarin in acute experimental pancreatitis].
Topics: Acute Disease; Animals; Choline; Cytidine Diphosphate Choline; Estrogens, Conjugated (USP); Male; Pancreatitis; Rats | 1976 |
Effect of intravenous injection of CDP-choline, S-adenosyl-methionine and citiolone in subjects with hyperlipemia.
Topics: Adult; Cholesterol; Choline; Cytidine Diphosphate Choline; Female; Humans; Hyperlipidemias; In Vitro Techniques; Injections, Intravenous; Lipids; Lipoproteins, HDL; Lipoproteins, LDL; Male; Middle Aged; S-Adenosylmethionine; Thiophenes; Triglycerides | 1979 |
Intestinal absorption of cytidine diphosphate choline and its changes in the digestive tract.
Topics: Animals; Carbon Dioxide; Carbon Radioisotopes; Choline; Cytidine; Cytidine Diphosphate Choline; Gastric Mucosa; Hydrogen-Ion Concentration; Intestinal Absorption; Intestinal Mucosa; Intestine, Small; Liver; Rats; Solubility; Tritium | 1975 |
Formation of 1-beta-D-arabinofuranosylcytosine diphosphate choline in cultured human leukemic RPMI 6410 cells.
Topics: 3-Deazauridine; Animals; Cell Division; Cells, Cultured; Choline; Cytarabine; Cytidine Diphosphate Choline; Drug Synergism; Humans; Hydrolysis; Leukemia, Experimental; Leukemia, Myeloid, Acute | 1978 |
Formation of 1-beta-D-arabinofuranosylcytosine diphosphate choline in neoplastic and normal cells.
Topics: 3-Deazauridine; Animals; Choline; Cytarabine; Cytidine Diphosphate Choline; Drug Synergism; Female; HeLa Cells; Leukemia L1210; Leukemia, Experimental; Leukemia, Myeloid, Acute; Liver; Lymphocytes; Mice; Mice, Inbred Strains | 1978 |
[Antagonism of barbituric coma by stimulating products. Experimental study].
Topics: Animals; Body Weight; Choline; Coma; Cytidine Diphosphate Choline; Female; Glycolates; Injections, Intraperitoneal; Lethal Dose 50; Male; Meclofenoxate; Mice; Phenobarbital; Piracetam; Pyridoxine; Pyrrolidinones; Reflex; Respiration | 1978 |
Nucleotides and sugar nucleotides in early development of Bufo arenarum. Coelomic oocytes.
Topics: Animals; Bufo arenarum; Choline; Cytidine Diphosphate Choline; Female; Nucleoside Diphosphate Sugars; Nucleotides; Oocytes; Oogenesis; Ovum; Pentoses | 1977 |
Effects of cytidine-5' diphosphocholine on norepinephrine, dopamine and serotonin synthesis in various regions of the rat brain.
Topics: Animals; Brain; Choline; Cytidine Diphosphate Choline; Dopamine; Male; Norepinephrine; Rats; Serotonin; Stimulation, Chemical | 1979 |
[Metabolic therapy of atherosclerosis].
Topics: Aged; Arteriosclerosis; Arteriosclerosis Obliterans; Choline; Cytidine Diphosphate Choline; Drug Therapy, Combination; Female; Humans; Intracranial Arteriosclerosis; Male; Theophylline; Xanthinol Niacinate | 1979 |
[Increased production of alveolar surfactant in the human fetus after treatment with cytidine diphosphocholine].
Topics: Adult; Amniotic Fluid; Choline; Cytidine Diphosphate Choline; Female; Fetus; Humans; Phosphatidylcholines; Pregnancy; Pulmonary Surfactants; Sphingomyelins | 1977 |
[Rheographic evaluation of the cerebral angio-hemodynamic effects of cytidine diphosphate choline in arteriosclerotic ictal syndromes].
Topics: Aged; Cerebrovascular Circulation; Cerebrovascular Disorders; Choline; Cytidine Diphosphate Choline; Drug Evaluation; Female; Hemiplegia; Humans; Injections, Intravenous; Intracranial Arteriosclerosis; Male; Middle Aged | 1977 |
Effect of cytidine diphosphate choline on growth hormone and prolactin secretion in man.
Topics: Adolescent; Adult; Choline; Cytidine Diphosphate Choline; Growth Hormone; Humans; Male; Prolactin | 1978 |
Action of cytidine diphosphocholine on functional and hemodynamic effects of cerebral ischemia in cats.
Topics: Animals; Blood Pressure; Cats; Cerebral Cortex; Choline; Cytidine Diphosphate Choline; Drug Evaluation, Preclinical; Evoked Potentials; Female; Heart Rate; Ischemic Attack, Transient | 1978 |
[Cytidine diphosphate cholinne -- a new drug in the treatment of spasticity].
Topics: Choline; Cytidine Diphosphate Choline; Drug Evaluation; Humans; Injections, Intravenous; Muscle Contraction; Muscle Spasticity | 1978 |
Phospholipid biosynthesis in the anaerobic protozoon Entodinium caudatum.
Topics: Anaerobiosis; Autoradiography; Ceramides; Choline; Ciliophora; Cytidine Diphosphate Choline; Cytosine Nucleotides; Ethanolamines; Fatty Acids; Methionine; Phosphatidylethanolamines; Phosphatidylinositols; Phospholipids; Serine; Sonication | 1975 |
[The place of citicolin in pulmonological therapy (author's transl)].
Topics: Animals; Choline; Cytidine Diphosphate Choline; Female; Humans; Infant, Newborn; Lipids; Lung; Maternal-Fetal Exchange; Phospholipids; Pregnancy; Pulmonary Surfactants; Rabbits; Rats; Respiratory Distress Syndrome, Newborn; Respiratory Insufficiency; Respiratory Tract Diseases; Surface Properties | 1976 |
The metabolism of labelled choline in neuronal and glial cells of the rabbit in vivo.
Topics: Animals; Cerebral Cortex; Choline; Cytidine Diphosphate Choline; Female; Injections, Intraventricular; Male; Neuroglia; Neurons; Phosphatidylcholines; Phospholipids; Rabbits; Sphingomyelins | 1977 |
Phospholipid metabolism during renal regeneration after acute tubular necrosis.
Topics: Acute Kidney Injury; Animals; Blood Urea Nitrogen; Cell Membrane; Choline; Cytidine Diphosphate Choline; Disease Models, Animal; Kidney; Kidney Tubular Necrosis, Acute; Male; Mercury; Phosphatidylcholines; Phospholipids; Rats; Regeneration | 1977 |
Stimulation of CDP-choline biosynthesis by enantiomeric lysophosphatidylcholines in rat intestinal mucosa.
Topics: Animals; Choline; Columbidae; Cytidine Diphosphate Choline; Cytosol; Fatty Acids; Intestinal Mucosa; Liver; Lysophosphatidylcholines; Male; Nucleotidyltransferases; Phospholipases; Phospholipids; Phosphorylcholine; Rats; Stereoisomerism | 1977 |
[Effects of citidine diphosphocholine (citicholine) and phospholipids on the elastic properties of the lung and on the physico-chemical properties of the irrigation liquid].
Topics: Animals; Choline; Cytidine Diphosphate Choline; Lung; Lung Compliance; Male; Phospholipids; Rats; Therapeutic Irrigation | 1976 |
Biosynthesis of rat brain phosphatidylcholines from intracerebrally injected choline.
Topics: Animals; Brain; Choline; Cytidine Diphosphate Choline; Kinetics; Male; Phosphatidylcholines; Phospholipids; Rats; Time Factors | 1976 |
Phosphatidylcholine synthesis and pulmonary oxygen toxicity.
Topics: Animals; Choline; Cytidine Diphosphate Choline; Lung; Microsomes; Oleic Acids; Oxygen; Palmitic Acids; Phosphatidylcholines; Pulmonary Surfactants; Rabbits | 1976 |
Intrathecal pharmacotherapy in coma.
Topics: Adult; Aged; Brain Injuries; Choline; Coma; Cytidine Diphosphate Choline; Electroencephalography; Female; Humans; Injections, Spinal; Male; Meningoencephalitis; Middle Aged; Subarachnoid Hemorrhage; Time Factors | 1976 |
Pool sizes and metabolism of CDPCholine and CDPethanolamine in skeletal muscle.
Topics: Animals; Choline; Cytidine Diphosphate Choline; Cytosine Nucleotides; Ethanolamines; Liver; Male; Muscles; Phosphates; Phosphorylcholine; Rats | 1976 |
[Relation between citicoline and pulmonary surfactant. Recent acquisitions in the treatment of respiratory syndromes of the newborn].
Topics: Choline; Cytidine Diphosphate Choline; Humans; Hyaline Membrane Disease; Infant, Newborn; Pulmonary Atelectasis; Pulmonary Surfactants; Respiratory Distress Syndrome, Newborn | 1976 |
Intrathecal administration of CDP-choline into the lower lumbar subarachnoid space in two patients with post-traumatic akinetic mutism.
Topics: Aged; Akinetic Mutism; Brain Injuries; Choline; Cytidine Diphosphate Choline; Humans; Injections, Spinal; Male; Middle Aged; Subarachnoid Space | 1976 |
[Position of cyticholine in pneumologic therapy].
Topics: Choline; Cytidine Diphosphate Choline; Drug Evaluation; Humans; Hypoventilation; Infant, Newborn; Injections, Intramuscular; Pulmonary Surfactants; Respiratory Distress Syndrome, Newborn; Respiratory Insufficiency; Respiratory Tract Diseases | 1975 |
Effects of various cerebral metabolic activators on glucose metabolism of brain.
Topics: Animals; Blood Glucose; Brain; Choline; Cytidine Diphosphate Choline; Cytosine Nucleotides; Glucose; Glycolates; Lactates; Meclofenoxate; Perfusion; Pyridines; Pyrithioxin | 1975 |
Regulation of phospholipid biosynthesis in isolated rat hepatocytes. Effect of different substrates.
Topics: Animals; Choline; Cytidine Diphosphate Choline; Cytosine Nucleotides; Ethanolamines; Fatty Acids, Unsaturated; Glycerol; Liver; Male; Methionine; Methylation; Oleic Acids; Phosphatidylcholines; Phosphatidylethanolamines; Rats | 1975 |
Water-soluble phospholipid precursor pool-sizes in quick-frozen and unfrozen rat livers.
Topics: Animals; Betaine; Choline; Cytidine Diphosphate Choline; Cytosine Nucleotides; Ethanolamines; Freezing; Liver; Male; Phospholipids; Rats; Solubility | 1975 |
[Diurnal variation of serum cortisol and CDP-choline treatment of patients in the vegetative state].
Topics: Adolescent; Adult; Choline; Circadian Rhythm; Coma; Cytidine Diphosphate Choline; Female; Humans; Hydrocortisone; Male; Middle Aged | 1975 |
Studies on the intrathecal pharmacotherapy. Part I: CDP-choline.
Topics: Adolescent; Adult; Aged; Animals; Autoradiography; Brain; Brain Death; Brain Injuries; Choline; Consciousness; Cytidine Diphosphate Choline; Electroencephalography; Female; Humans; Injections, Spinal; Male; Middle Aged; Rats; Spinal Cord | 1975 |
Phosphorylation of mononucleotides and formation of cytidine 5'-diphosphate-choline and sugar nucleotides by respiration-deficient mutants of yeasts.
Topics: Acriflavine; Adenosine Triphosphate; Choline; Cytidine Diphosphate Choline; Glucose; Mutagens; Mutation; Nucleoside Diphosphate Sugars; Nucleotides; Oxygen Consumption; Saccharomyces | 1976 |
Metal ion complexes of cytidinediphosphocholine.
Topics: Binding Sites; Calcium; Choline; Cytidine Diphosphate Choline; Magnesium; Magnetic Resonance Spectroscopy; Manganese; Molecular Conformation; Quinolines; Spectrophotometry, Ultraviolet | 1976 |
Effects of amino acids and ethanolamine on choline uptake and phosphatidylcholine biosynthesis in baby hamster kidney-21 cells.
Topics: Amino Acids; Animals; Binding, Competitive; Cell Line; Choline; Cricetinae; Cytidine Diphosphate Choline; Ethanolamine; Ethanolamines; Kidney; Kinetics; Phosphatidylcholines | 1992 |
Phosphatidylcholine metabolism in ischemic and hypoxic hearts.
Topics: Adenosine Triphosphate; Animals; Biological Transport; Cell Hypoxia; Choline; Choline Kinase; Choline-Phosphate Cytidylyltransferase; Cricetinae; Cytidine Diphosphate Choline; Cytidine Triphosphate; Mesocricetus; Myocardial Ischemia; Nucleotidyltransferases; Phosphatidylcholines; Phosphorylcholine | 1992 |
Effects of cholinergic agents on the metabolism of choline in muscle from Ascaris suum.
Topics: Acetylcholine; Animals; Ascaris; Carbachol; Choline; Cytidine Diphosphate Choline; Female; Glycerylphosphorylcholine; Levamisole; Muscles; Phosphatidylcholines; Phosphorylcholine | 1992 |
Channeling of intermediates in the CDP-choline pathway of phosphatidylcholine biosynthesis in cultured glioma cells is dependent on intracellular Ca2+.
Topics: Animals; Calcium; Choline; Cytidine Diphosphate Choline; Electricity; Glioma; Permeability; Phosphatidylcholines; Rats; Tumor Cells, Cultured | 1991 |
Changes in brain biogenic monoamines induced by the nootropic drugs adafenoxate and meclofenoxate and by citicholine (experiments on rats).
Topics: Animals; Biogenic Monoamines; Brain Chemistry; Choline; Cytidine Diphosphate Choline; Dopamine; Glycolates; Male; Meclofenoxate; Norepinephrine; Rats; Rats, Inbred Strains; Serotonin | 1990 |
Altered phosphatidylcholine metabolism in C3H10T1/2 cells transfected with the Harvey-ras oncogene.
Topics: Animals; Carbon Radioisotopes; Cell Transformation, Neoplastic; Cells, Cultured; Choline; Choline Kinase; Cytidine Diphosphate Choline; Diacylglycerol Cholinephosphotransferase; Genes, ras; Kinetics; Mice; Phosphatidylcholines; Phospholipids; Radioisotope Dilution Technique; Transfection; Tritium | 1990 |
Study of the effects of oral administration of CDP-choline on open-field behaviour under conditions of chronic hypoxia.
Topics: Administration, Oral; Animals; Attention; Behavior, Animal; Choline; Chronic Disease; Cytidine Diphosphate Choline; Defecation; Hypoxia; Male; Motor Activity; Rats; Rats, Inbred Strains | 1990 |
31P NMR studies of cultured human tumor cells. Influence of pH on phospholipid metabolite levels and the detection of cytidine 5'-diphosphate choline.
Topics: Choline; Culture Media; Cytidine Diphosphate Choline; Humans; Hydrogen-Ion Concentration; In Vitro Techniques; Magnetic Resonance Spectroscopy; Phospholipids; Tumor Cells, Cultured | 1990 |
Effects of citicholine and of the combination citicholine + piracetam on the memory (experiments on mice).
Topics: Amnesia; Animals; Avoidance Learning; Choline; Cytidine Diphosphate Choline; Male; Memory; Mice; Models, Psychological; Piracetam; Pyrrolidinones; Scopolamine | 1990 |
Effect of cytidine diphosphate choline on ultraviolet-induced brain edema.
Topics: Animals; Body Water; Brain Chemistry; Brain Edema; Cats; Choline; Cytidine Diphosphate Choline; Radiation Injuries, Experimental; Ultraviolet Rays | 1990 |
[The effects on the learning process of 4 pyrrolidine derivatives and of cyticholine (experiments on rats in a water maze)].
Topics: Animals; Choline; Cytidine Diphosphate Choline; Learning; Male; Pyrrolidines; Rats; Rats, Inbred Strains; Structure-Activity Relationship; Swimming | 1990 |
[Effect of CDP-choline on the action of cholecystokinin and carbachol to stimulate amylase secretion from dispersed rat pancreatic acini].
Topics: Amylases; Animals; Carbachol; Cholecystokinin; Choline; Cytidine Diphosphate Choline; In Vitro Techniques; Male; Pancreas; Phospholipases A; Rats; Rats, Inbred Strains | 1986 |
Effect of hyperpnea on enzymes of the CDPcholine path for phosphatidylcholine synthesis in rat lung.
Topics: Animals; Choline; Choline Kinase; Choline-Phosphate Cytidylyltransferase; Cytidine Diphosphate Choline; Cytosol; Diacylglycerol Cholinephosphotransferase; Hyperventilation; Kinetics; Lung; Male; Microsomes; Nucleotidyltransferases; Phosphatidylcholines; Phospholipids; Phosphorylcholine; Pulmonary Ventilation; Rats; Swimming; Tidal Volume | 1989 |
Induction of phosphatidylcholine biosynthesis via CDPcholine pathway in lung and liver of rats following intratracheal administration of DDT and endosulfan.
Topics: Animals; Choline; Choline Kinase; Choline-Phosphate Cytidylyltransferase; Cytidine Diphosphate Choline; DDT; Endosulfan; Intubation, Intratracheal; Lung; Male; Microsomes; Microsomes, Liver; Nucleotidyltransferases; Phosphatidylcholines; Phosphorylcholine; Rats; Rats, Inbred Strains; Scintillation Counting | 1989 |
Influence of CDP-choline administration on the aortic wall lesions in dietically hypercholesterolaemic rabbits: a morphometric evaluation.
Topics: Animals; Aorta; Cholesterol; Cholesterol, Dietary; Choline; Cytidine Diphosphate Choline; Diet; Hypercholesterolemia; Rabbits; Vascular Diseases | 1989 |
Therapeutic value of citicoline in the treatment of glaucoma (computerized and automated perimetric investigation).
Topics: Adult; Aged; Choline; Cytidine Diphosphate Choline; Glaucoma, Open-Angle; Humans; Middle Aged; Scotoma; Time Factors; Visual Field Tests; Visual Fields | 1989 |
Phosphatidylcholine biosynthesis in cultured glioma cells: evidence for channeling of intermediates.
Topics: Animals; Cell Membrane Permeability; Choline; Cytidine Diphosphate Choline; Electricity; Models, Biological; Phosphatidylcholines; Phosphorylcholine; Rats; Tumor Cells, Cultured | 1989 |
Non-enzymatic synthesis of the coenzymes, uridine diphosphate glucose and cytidine diphosphate choline, and other phosphorylated metabolic intermediates.
Topics: Choline; Cytidine Diphosphate Choline; Cytidine Triphosphate; Glucosephosphate Dehydrogenase; Glucosephosphates; Indicators and Reagents; Phosphoric Diester Hydrolases; Phosphorylcholine; Uridine Diphosphate Glucose; Uridine Diphosphate Sugars | 1987 |
Effects of CDP-choline on phospholipase A2 and cholinephosphotransferase activities following a cryogenic brain injury in the rabbit.
Topics: Animals; Brain; Calcium; Choline; Cold Temperature; Cytidine Diphosphate Choline; Diacylglycerol Cholinephosphotransferase; Female; Phospholipases; Phospholipases A; Phospholipases A2; Phospholipids; Phosphotransferases; Rabbits | 1987 |
Choline turnover in phosphatidylcholine of pancreatic islets. Implications for CDP-choline pathway.
Topics: Acetophenones; Animals; Calcium; Choline; Cytidine Diphosphate Choline; Deoxyadenosines; Dronabinol; Enzyme Activation; Glucose; Islets of Langerhans; Male; Melitten; Phosphatidylcholines; Phospholipases A; Phospholipases A2; Rats; Rats, Inbred Strains; Thionucleosides; Type C Phospholipases | 1988 |
Bradykinin stimulates phosphodiesteratic cleavage of phosphatidylcholine in cultured endothelial cells.
Topics: Animals; Bradykinin; Cattle; Cell Line; Choline; Cytidine Diphosphate Choline; Diglycerides; Endothelium, Vascular; Glycerol; Glycerylphosphorylcholine; Kinetics; Myristic Acid; Myristic Acids; Phosphatidic Acids; Phosphatidylcholines; Phosphoric Diester Hydrolases; Phosphorylcholine; Pulmonary Artery | 1988 |
[Use of citicoline in the study of chronic cerebrovascular diseases].
Topics: Adrenergic beta-Antagonists; Aged; Choline; Chronic Disease; Cytidine Diphosphate Choline; Diuretics; Drug Evaluation; Female; Humans; Hypertension; Intracranial Arteriosclerosis; Male; Neuropsychological Tests; Vasodilator Agents | 1988 |
Co-ordinate control of CDP-choline and phosphatidylethanolamine methyltransferase pathways for phosphatidylcholine biosynthesis occurs in response to change in diet fat.
Topics: Animals; Brain; Choline; Cytidine Diphosphate Choline; Dietary Fats; Fatty Acids; Male; Membrane Lipids; Methyltransferases; Phosphatidylcholines; Phosphatidylethanolamine N-Methyltransferase; Rats; Rats, Inbred Strains; Synaptic Membranes | 1989 |
[Pathological aging of the brain. Personal observations on the use of citicoline].
Topics: Aged; Aged, 80 and over; Cerebrovascular Disorders; Choline; Chronic Disease; Cytidine Diphosphate Choline; Dementia, Vascular; Drug Evaluation; Female; Humans; Male; Middle Aged; Psychiatric Status Rating Scales | 1988 |
Phosphatidylcholine synthesis in adult Dirofilaria immitis females.
Topics: Animals; Choline; Cytidine Diphosphate Choline; Diacylglycerol Cholinephosphotransferase; Dirofilaria immitis; Female; Filarioidea; Methylation; Methyltransferases; Phosphatidylcholines; Phosphatidylethanolamine N-Methyltransferase; Phosphatidylethanolamines; S-Adenosylmethionine | 1985 |
The effects of ischemia and CDPamines on Na+, K+-ATPase and acetylcholinesterase activities in rat brain.
Topics: Acetylcholinesterase; Animals; Brain Ischemia; Cerebral Cortex; Choline; Corpus Striatum; Cytidine Diphosphate; Cytidine Diphosphate Choline; Cytosine Nucleotides; Ethanolamines; Male; Rats; Rats, Inbred Strains; Sodium-Potassium-Exchanging ATPase | 1985 |
De novo CDP-choline-dependent glycerophosphorylcholine synthesis and its involvement as an intermediate in phosphatidylcholine synthesis.
Topics: Animals; Choline; Cytidine Diphosphate Choline; Glycerylphosphorylcholine; In Vitro Techniques; Liver; Male; Nitrogenous Group Transferases; Phosphatidylcholines; Phosphotransferases; Rats; Rats, Inbred Strains | 1987 |
Effect of CDP-choline on hypocapnic neurons in culture.
Topics: Animals; Brain; Carbon Dioxide; Cell Aggregation; Cells, Cultured; Chick Embryo; Choline; Cytidine Diphosphate Choline; Neurons | 1986 |
Circling behaviour in rats with unilateral lesions of the nigrostriatum induced by 6-hydroxydopamine: changes induced by oral administration of cytidine-5'-diphosphocholine.
Topics: Administration, Oral; Amphetamine; Animals; Apomorphine; Behavior, Animal; Choline; Corpus Striatum; Cytidine Diphosphate Choline; Hydroxydopamines; Levodopa; Male; Oxidopamine; Rats; Rats, Inbred Strains; Substantia Nigra | 1987 |
Effects of the nootropic agents adafenoxate, meclofenoxate and the acetylcholine precursor citicholine on the brain muscarinic receptors (experiments on rats).
Topics: Acetylcholine; Animals; Brain; Choline; Cytidine Diphosphate Choline; Glycolates; Male; Meclofenoxate; Radioligand Assay; Rats; Rats, Inbred Strains; Receptors, Muscarinic | 1987 |
Effects of meclofenoxate and citicholine on learning and memory in aged rats.
Topics: Aging; Animals; Choline; Cytidine Diphosphate Choline; Glycolates; Learning; Male; Meclofenoxate; Memory; Rats; Rats, Inbred Strains; Scopolamine | 1987 |
Comparative studies on the effects of the nootropic drugs adafenoxate, meclofenoxate and piracetam, and of citicholine on scopolamine-impaired memory, exploratory behavior and physical capabilities (experiments on rats and mice).
Topics: Animals; Avoidance Learning; Choline; Cytidine Diphosphate Choline; Exploratory Behavior; Glycolates; Male; Meclofenoxate; Memory; Mice; Mice, Inbred Strains; Piracetam; Psychomotor Performance; Pyrrolidinones; Rats; Rats, Inbred Strains; Scopolamine | 1988 |
[3H]arachidonic acid metabolism in rat brain minces: effects of nucleotide triphosphates, CDPcholine and CMP.
Topics: Animals; Arachidonic Acid; Arachidonic Acids; Brain; Choline; Cytidine Diphosphate Choline; Cytidine Monophosphate; Cytosine Nucleotides; Male; Phospholipids; Purine Nucleotides; Pyrimidine Nucleotides; Rats; Rats, Inbred Strains | 1988 |
Phosphatidylcholine synthesis in yeast.
Topics: Choline; Cytidine Diphosphate Choline; Ethionine; Methionine; Methylation; Mutation; Phosphatidylcholines; Phosphatidylethanolamines; S-Adenosylmethionine; Saccharomyces cerevisiae | 1988 |
Effects of CDP-choline on neurologic deficits and cerebral glucose metabolism in a rat model of cerebral ischemia.
Topics: Animals; Brain; Brain Ischemia; Carbon Radioisotopes; Cerebral Cortex; Choline; Cytidine Diphosphate Choline; Glucose; Male; Motor Activity; Posture; Rats; Rats, Inbred Strains; Reflex | 1988 |
Effect of amino acids on choline uptake and phosphatidylcholine biosynthesis in the isolated hamster heart.
Topics: Amino Acids; Animals; Choline; Cricetinae; Cytidine Diphosphate Choline; In Vitro Techniques; Mesocricetus; Myocardium; Phosphatidylcholines | 1988 |
Choline glycerophospholipid biosynthesis in the guinea pig heart.
Topics: Animals; Choline; Cytidine Diphosphate Choline; Ethanolamine; Ethanolamines; Guinea Pigs; In Vitro Techniques; Kinetics; Male; Myocardium; Phosphatidylcholines | 1987 |
Rapid formation of diacylglycerol from phosphatidylcholine: a pathway for generation of a second messenger.
Topics: Cells, Cultured; Choline; Cytidine Diphosphate Choline; Diglycerides; Fetal Blood; Glycerides; Phorbol 12,13-Dibutyrate; Phorbol Esters; Phosphatidic Acids; Phosphatidylcholines; Platelet-Derived Growth Factor; Protein Kinase C; Type C Phospholipases | 1986 |
Effects of CDP-choline on platelet aggregation and the antiaggregatory activity of arterial wall in the rat.
Topics: Animals; Aorta, Thoracic; Arteries; Choline; Cytidine Diphosphate Choline; Epithelium; Epoprostenol; In Vitro Techniques; Male; Perfusion; Platelet Aggregation; Rats; Thromboxane B2; Time Factors | 1986 |
Phosphatidylcholine synthesis for incorporation into membranes or for secretion as plasma lipoproteins by Golgi membranes of rat liver.
Topics: Animals; Choline; Cytidine Diphosphate Choline; Golgi Apparatus; Intracellular Membranes; Lipoproteins; Liver; Male; Methionine; Microsomes, Liver; Phosphatidylcholines; Rats; Rats, Inbred Strains | 1987 |
Effects of hypoxia and cytidine (5') diphosphocholine on the concentrations of dopamine, norepinephrine and metabolites in rat hypothalamus and striatum.
Topics: 3,4-Dihydroxyphenylacetic Acid; Animals; Choline; Chromatography, High Pressure Liquid; Corpus Striatum; Cytidine Diphosphate Choline; Dopamine; Electrochemistry; Homovanillic Acid; Hypothalamus; Hypoxia; Male; Norepinephrine; Rats; Rats, Inbred Strains | 1987 |
Choline incorporation by Schistosoma mansoni: distribution of choline metabolites during development and after sexual differentiation.
Topics: Animals; Betaine; Carbon Radioisotopes; Choline; Cytidine Diphosphate Choline; Female; Male; Phosphatidylcholines; Phosphorylcholine; Schistosoma mansoni; Sex Differentiation | 1987 |
[Thrombocytopenia secondary to citicholine].
Topics: Aged; Cerebrovascular Disorders; Choline; Cytidine Diphosphate Choline; Female; Humans; Thrombocytopenia | 1987 |
[Use of citicoline in high dosages in acute cerebrovascular disease].
Topics: Acute Disease; Aged; Brain Ischemia; Cerebral Hemorrhage; Choline; Coma; Consciousness; Cytidine Diphosphate Choline; Electroencephalography; Female; Humans; Language Disorders; Male; Middle Aged; Paralysis | 1986 |
[Neuropsychological study of the senile brain during and after single and combined treatment with deanol and citicoline].
Topics: Aged; Choline; Cytidine Diphosphate Choline; Deanol; Dementia; Double-Blind Method; Drug Evaluation; Drug Therapy, Combination; Ethanolamines; Female; Humans; Male | 1986 |
Effect of cytidine(5')diphosphocholine (CDP-choline) on the total urinary excretion of 3-methoxy-4-hydroxyphenylglycol (MHPG) by rats and humans.
Topics: Administration, Oral; Adult; Animals; Choline; Cytidine Diphosphate Choline; Glycols; Humans; Male; Methoxyhydroxyphenylglycol; Norepinephrine; Rats; Rats, Inbred Strains; Species Specificity | 1986 |
The supply of both CDP-choline and diacylglycerol can regulate the rate of phosphatidylcholine synthesis in HeLa cells.
Topics: Acyl Coenzyme A; Carbon Radioisotopes; Cell Membrane Permeability; Choline; Cytidine Diphosphate Choline; HeLa Cells; Humans; Microsomes; Phosphatidylcholines; Tritium | 1986 |
[CDP choline and experimental cerebrovascular disorder].
Topics: Animals; Blood-Brain Barrier; Brain; Brain Ischemia; Choline; Cytidine Diphosphate Choline; Drug Evaluation, Preclinical; Histocytochemistry; Male; Rats; Rats, Inbred Strains | 1986 |
[Cerebral protection by CDP choline during surgical action].
Topics: Adult; Aged; Brain; Carotid Arteries; Choline; Cytidine Diphosphate Choline; Endarterectomy; Female; Humans; Injections, Intravenous; Male; Middle Aged; Postoperative Care; Preoperative Care | 1986 |
Synthesis of phosphatidylcholine by rat lung during choline deficiency.
Topics: Animals; Carbon Radioisotopes; Choline; Choline Deficiency; Cytidine Diphosphate Choline; Glucose; Lung; Male; Palmitic Acid; Palmitic Acids; Phosphatidylcholines; Phosphorylcholine; Rats; Rats, Inbred Strains | 1986 |
Evidence for a high activity of sphingomyelin biosynthesis by phosphocholine transfer from phosphatidylcholine to ceramides in lung lamellar bodies.
Topics: Albumins; Animals; Calcium; Ceramides; Choline; Cytidine Diphosphate Choline; Hydrogen-Ion Concentration; Kinetics; Lung; Lysophosphatidylcholines; Male; Manganese; Phosphatidylcholines; Phosphorylcholine; Rats; Rats, Inbred Strains; Sphingomyelins; Subcellular Fractions | 1987 |
[Respiratory function and alveolar biological changes under the effect of CDP-choline in pulmonary interstitial pathology: pulmonary fibrosis and sarcoidosis].
Topics: Adult; Aged; Choline; Cytidine Diphosphate Choline; Female; Humans; Injections, Intramuscular; Lung Diseases; Male; Middle Aged; Phosphatidylcholines; Pulmonary Alveoli; Pulmonary Fibrosis; Pulmonary Gas Exchange; Pulmonary Surfactants; Respiratory Function Tests; Sarcoidosis | 1985 |
[Clinical flow sonographic and telethermographic evaluation of arteriopathy patients treated with CDP-choline].
Topics: Aged; Arterial Occlusive Diseases; Choline; Cytidine Diphosphate Choline; Female; Humans; Leg; Male; Middle Aged; Regional Blood Flow; Thermography; Ultrasonography | 1985 |
Oxotremorine-induced cholinergic syndrome: modifications by levodopa and/or oral cytidine diphosphocholine.
Topics: Administration, Oral; Animals; Choline; Cytidine Diphosphate Choline; Diarrhea; Female; Hypothermia; Levodopa; Mice; Oxotremorine; Salivation; Syndrome; Tremor | 1985 |
Topological biosynthesis of phosphatidylcholine in brain microsomes.
Topics: Animals; Biological Transport; Brain; Chickens; Choline; Cytidine Diphosphate Choline; Intracellular Membranes; Kinetics; Lipid Bilayers; Microsomes; Phosphatidylcholines; Phosphorylcholine; Rats | 1985 |
[Agentss to improve cerebrovascular circulation and cerebral metabolism--citicoline].
Topics: Animals; Brain; Cerebrovascular Circulation; Cerebrovascular Disorders; Choline; Cytidine Diphosphate Choline; Humans; Oxygen Consumption; Rabbits; Rats | 1985 |
[CDP choline and cerebrovascular insufficiency in the elderly. Clinical study of 40 patients undergoing prolonged treatment].
Topics: Aged; Cerebrovascular Disorders; Choline; Cytidine Diphosphate Choline; Female; Follow-Up Studies; Humans; Male; Middle Aged | 1985 |
Partial protection by CDP-choline against kainic acid-induced lesion in the rat caudate nucleus.
Topics: 3,4-Dihydroxyphenylacetic Acid; Animals; Caudate Nucleus; Choline; Cytidine Diphosphate Choline; Dopamine; Kainic Acid; Levodopa; Male; Rats; Rats, Inbred Strains; Receptors, Dopamine; Spiperone; Time Factors | 1985 |
Evidence for a different metabolic behaviour of cytidine diphosphate choline after oral and intravenous administration to rats.
Topics: Administration, Oral; Animals; Carbon Radioisotopes; Choline; Cytidine Diphosphate Choline; Injections, Intravenous; Kinetics; Male; Rats; Rats, Inbred Strains; Tissue Distribution | 1985 |
Transport and metabolism of double-labelled CDPcholine in mammalian tissues.
Topics: Animals; Biological Transport; Carbon Radioisotopes; Choline; Cytidine Diphosphate Choline; Kinetics; Liver; Male; Phospholipids; Rats; Rats, Inbred Strains; Tritium | 1985 |
Choline incorporation into phospholipids by microsomal fractions from L5178Y lymphoma.
Topics: Animals; Calcium; Cell Line; Choline; Cytidine Diphosphate Choline; Egtazic Acid; Hydrogen-Ion Concentration; Kinetics; Leukemia, Lymphoid; Magnesium; Mice; Microsomes; Phospholipids; Temperature; Time Factors | 1974 |
CDP-choline as a drug for pancreatitis.
Topics: Acute Disease; Adult; Choline; Cytidine Diphosphate Choline; Female; Humans; Male; Middle Aged; Pancreatitis; Phospholipases | 1974 |
Inhibitors of CDP-choline synthesis, action potential calcium channels, and stimulus-secretion coupling.
Topics: Acetylcholine; Action Potentials; Animals; Calcium; Choline; Choline-Phosphate Cytidylyltransferase; Cytidine Diphosphate Choline; Deoxyadenosines; Hybrid Cells; Ion Channels; Mice; Motor Endplate; Nucleotidyltransferases; Phosphatidylcholines; Rats; Receptors, Nicotinic; S-Adenosylhomocysteine; S-Adenosylmethionine; Thionucleosides; Tubercidin | 1984 |
Activation of soluble striatal tyrosine hydroxylase in the rat brain after CDPcholine administration.
Topics: Animals; Choline; Corpus Striatum; Cytidine Diphosphate Choline; Enzyme Activation; Male; Rats; Solubility; Tyrosine 3-Monooxygenase | 1981 |
Effect of CDP-choline on the biosynthesis of nucleic acids and proteins in brain regions during hypoxia.
Topics: Animals; Brain; Choline; Cytidine Diphosphate Choline; DNA; Female; Guinea Pigs; Hypoxia; Nerve Tissue Proteins; RNA; Subcellular Fractions | 1981 |
Relationship between cytidine 5'diphosphocholine epitope density on ovalbumin and IgE antibody responses compared to other isotypes.
Topics: Animals; Choline; Cytidine Diphosphate Choline; Epitopes; Hemagglutinins; Immunoglobulin E; Mice; Mice, Inbred BALB C; Molecular Conformation; Ovalbumin; Passive Cutaneous Anaphylaxis; Rats; Rats, Inbred Lew | 1983 |
Cerebral subcellular distribution of CDP-choline and/or its metabolites after oral administration of methyl-14C CDP-choline.
Topics: Administration, Oral; Animals; Brain; Centrifugation; Centrifugation, Density Gradient; Choline; Cytidine Diphosphate Choline; Male; Rats; Specific Pathogen-Free Organisms; Subcellular Fractions | 1983 |
Poliovirus increases phosphatidylcholine biosynthesis in HeLa cells by stimulation of the rate-limiting reaction catalyzed by CTP: phosphocholine cytidylyltransferase.
Topics: Cell Transformation, Viral; Choline; Cytidine Diphosphate Choline; Cytidine Triphosphate; Enzyme Activation; HeLa Cells; Humans; Kinetics; Nucleotidyltransferases; Phosphatidylcholines; Poliovirus; Ribonucleotides | 1980 |
Regulation of phosphatidylcholine biosynthesis in cultured chick embryonic muscle treated with phospholipase C.
Topics: Animals; Chick Embryo; Choline; Choline-Phosphate Cytidylyltransferase; Cycloheximide; Cytidine Diphosphate Choline; Kinetics; Muscles; Nucleotidyltransferases; Phosphatidylcholines; Phosphatidylethanolamines; Phospholipases; Type C Phospholipases | 1980 |
Autoradiographic detection of animal cell membrane mutants altered in phosphatidylcholine synthesis.
Topics: Animals; Autoradiography; Cell Line; Choline; Choline-Phosphate Cytidylyltransferase; Clone Cells; Cricetinae; Cricetulus; Cytidine Diphosphate Choline; Female; Membrane Lipids; Mutation; Nucleotidyltransferases; Ovary; Phosphatidylcholines; Temperature | 1980 |
The effects of metabolism improving agents: an electrophysiological study.
Topics: Adenosine Triphosphate; Animals; Arousal; Brain; Cerebral Cortex; Choline; Cytidine Diphosphate Choline; Cytochrome c Group; Electric Conductivity; Evoked Potentials; Glycolates; Hippocampus; Meclofenoxate; Muscles; Rabbits | 1980 |
Tetradecanoyl-phorbol acetate stimulates phosphatidylcholine biosynthesis in HeLa cells by an increase in the rate of the reaction catalyzed by CTP:phosphocholine cytidylyltransferase.
Topics: Choline; Choline-Phosphate Cytidylyltransferase; Cytidine Diphosphate Choline; HeLa Cells; Humans; Nucleotidyltransferases; Phorbol Esters; Phorbols; Phosphatidylcholines; Stimulation, Chemical | 1980 |
1,2-diacylglycerol: CDPcholine cholinephosphotransferase.
Topics: Animals; Choline; Cytidine Diphosphate Choline; Diacylglycerol Cholinephosphotransferase; Diglycerides; Glycerides; Liver; Methods; Phosphotransferases; Rats | 1981 |
Evidence for a regulatory role of CTP : choline phosphate cytidylyltransferase in the synthesis of phosphatidylcholine in fetal lung following premature birth.
Topics: Animals; Animals, Newborn; Choline; Choline-Phosphate Cytidylyltransferase; Cytidine Diphosphate Choline; Cytosol; Female; Lung; Microsomes; Nucleotidyltransferases; Phosphatidylcholines; Phosphorylcholine; Pregnancy; Rats | 1981 |
Studies on CDP-choline:1,2-diacylglycerol cholinephosphotransferase activity in rat arterial wall.
Topics: Animals; Aorta; Barium; Calcium; Choline; Cytidine Diphosphate Choline; Diacylglycerol Cholinephosphotransferase; Diglycerides; Edetic Acid; Hydrogen-Ion Concentration; Magnesium; Male; Manganese; Octoxynol; Phosphatidylcholines; Phosphotransferases; Polyethylene Glycols; Rats; Rats, Inbred Strains | 1982 |
Synaptosomes and mitochondria from rat brain cerebral cortex: in vivo interference on some enzymatic activities by SAMe and CDP-choline.
Topics: Acetylcholinesterase; Animals; Cerebral Cortex; Choline; Citrate (si)-Synthase; Cytidine Diphosphate Choline; Electron Transport Complex IV; Female; Malate Dehydrogenase; Mitochondria; NADH Dehydrogenase; Rats; S-Adenosylmethionine; Synaptosomes | 1982 |
Yeast mutant with thermolabile CDP-choline synthesis. Isolation and characterization of a cholinephosphate cytidyltransferase mutant.
Topics: Choline; Choline-Phosphate Cytidylyltransferase; Cytidine Diphosphate Choline; Hot Temperature; Mutation; Nucleotidyltransferases; RNA Nucleotidyltransferases; Saccharomyces cerevisiae | 1983 |
Hormonal regulation of phosphatidylcholine synthesis in plants. The inhibition of cytidylyltransferase activity by indol-3-ylacetic acid.
Topics: Choline; Choline-Phosphate Cytidylyltransferase; Cytidine Diphosphate Choline; Fabaceae; Indoleacetic Acids; Nucleotidyltransferases; Phosphatidylcholines; Phosphorylcholine; Plant Development; Plants; Plants, Medicinal | 1983 |
Identification of cytidine diphosphodiesters in erythrocytes from a patient with pyrimidine nucleotidase deficiency.
Topics: 5'-Nucleotidase; Adult; Anemia, Hemolytic, Congenital Nonspherocytic; Choline; Cytidine Diphosphate; Cytidine Diphosphate Choline; Cytosine Nucleotides; Erythrocyte Membrane; Erythrocytes; Ethanolamines; Humans; Magnetic Resonance Spectroscopy; Male; Mass Spectrometry; Nucleotidases; Phospholipids | 1984 |
Regulation of phosphatidylcholine metabolism in mammalian cells. Isolation and characterization of a Chinese hamster ovary cell pleiotropic mutant defective in both choline kinase and choline-exchange reaction activities.
Topics: Animals; Autoradiography; Cell Line; Choline; Choline Kinase; Cricetinae; Cricetulus; Cytidine Diphosphate Choline; Ethanolamine; Ethanolamines; Female; Nitrogenous Group Transferases; Ovary; Phosphatidylcholines; Phosphorylcholine; Phosphotransferases; Serine; Transferases | 1984 |
Red cell CDP (dCDP)-choline and P-choline in normal subjects and in certain hemolytic syndromes.
Topics: 5'-Nucleotidase; Anemia, Hemolytic; Choline; Cytidine Diphosphate Choline; Erythrocytes; Humans; Nucleotidases; Phosphatidylcholines; Phosphorylcholine; Reticulocytes | 1984 |
Glucagon inhibits phosphatidylcholine biosynthesis via the CDP-choline and transmethylation pathways in cultured rat hepatocytes.
Topics: Animals; Betaine; Cells, Cultured; Choline; Cytidine Diphosphate Choline; Depression, Chemical; Fatty Acids; Female; Glucagon; Insulin; Liver; Methylation; Phosphatidylcholines; Phosphatidylethanolamines; Rats; Rats, Inbred Strains | 1984 |
Pharmacokinetics of 14C CDP-choline.
Topics: Adult; Breath Tests; Carbon Dioxide; Choline; Cytidine Diphosphate Choline; Diet; Feces; Humans; Kinetics; Male; Time Factors | 1983 |
Regulation of ethanolamine and choline phosphatide biosynthesis in isolated rat intestinal villus cells.
Topics: Animals; Chlormequat; Choline; Cytidine Diphosphate; Cytidine Diphosphate Choline; Docosahexaenoic Acids; Ethanolamines; Fatty Acids; Glucose; Intestinal Mucosa; Intestines; Lauric Acids; Male; Methylation; Microsomes; Microsomes, Liver; Oleic Acids; Palmitic Acids; Phosphatidylcholines; Phosphatidylethanolamines; Rats | 1980 |
The rate-limiting reaction in phosphatidylcholine synthesis by alveolar type II cells isolated from fetal rat lung.
Topics: Animals; Choline; Cytidine Diphosphate Choline; Female; Fetus; Kinetics; Lung; Phosphatidylcholines; Phosphorylcholine; Pregnancy; Rats; Tritium | 1984 |
[Experimental studies on pathophysiology of acute pancreatitis, with special reference to pancreatic phospholipase A2 and the effect of CDP-choline].
Topics: Acute Disease; Animals; Choline; Cytidine Diphosphate Choline; Dogs; Liver; Pancreatitis; Phospholipases; Phospholipases A; Phospholipases A2 | 1984 |
CDP-choline does not inhibit erythrocyte glycolytic or pentose phosphate pathway enzyme activity.
Topics: Choline; Cytidine Diphosphate Choline; Enzymes; Erythrocytes; Glycolysis; Humans; Pentose Phosphate Pathway | 1984 |
Cytidine(5')diphosphocholine enhances the ability of haloperidol to increase dopamine metabolites in the striatum of the rat and to diminish stereotyped behavior induced by apomorphine.
Topics: 3,4-Dihydroxyphenylacetic Acid; Animals; Apomorphine; Choline; Corpus Striatum; Cytidine Diphosphate Choline; Dopamine; Drug Synergism; Haloperidol; Homovanillic Acid; Humans; Male; Rats; Rats, Inbred Strains; Stereotyped Behavior | 1984 |
Selective accumulation of cytosol CDP-choline as an isolated erythrocyte defect in chronic hemolysis.
Topics: Adolescent; Anemia, Hemolytic; Choline; Cytidine Diphosphate Choline; Cytosol; Erythrocyte Aging; Erythrocytes; Female; Humans; Pedigree; Spectrophotometry, Ultraviolet | 1983 |
CDP-choline: physico-chemical characteristics.
Topics: Chemical Phenomena; Chemistry, Physical; Choline; Chromatography, Thin Layer; Cytidine Diphosphate Choline; Drug Contamination | 1983 |
Cytidine diphosphate choline (citicoline, Somazina).
Topics: Animals; Choline; Cytidine Diphosphate Choline; Humans | 1983 |
Study of the effects of oral administration of CDP-choline on EEG changes and lethality induced by epidural compression in the anaesthetised cat.
Topics: Anesthesia; Animals; Brain; Cats; Choline; Cytidine Diphosphate Choline; Electroencephalography; Epidural Space; Hemodynamics; Male; Pressure; Respiration | 1983 |
Dissimilar effects in acute toxicity studies of CDP-choline and choline.
Topics: Administration, Oral; Animals; Choline; Cytidine Diphosphate Choline; Female; Injections, Intravenous; Lethal Dose 50; Male; Mice | 1983 |
Effect of oral CDP-choline on experimental withdrawal syndrome.
Topics: Animals; Behavior, Animal; Body Temperature; Choline; Cytidine Diphosphate Choline; Humans; Male; Mice; Morphine Dependence; Naloxone; Substance Withdrawal Syndrome; Time Factors | 1983 |
Pharmacological study of CDP-choline. Protection against toxicity in a model of experimental hypoxia.
Topics: Animals; Choline; Cytidine Diphosphate Choline; Hypoxia; Levodopa; Male; Mice; Potassium Cyanide; Time Factors | 1983 |
Study on the protection of CDP-choline against nicotine intoxication.
Topics: Animals; Choline; Cytidine Diphosphate Choline; Female; Male; Mice; Nicotine; Time Factors | 1983 |
Pharmacological study of oral CDP-choline. Interaction with oxotremorine on the parasympathetic system.
Topics: Animals; Body Temperature; Choline; Cytidine Diphosphate Choline; Diarrhea; Drug Interactions; Female; Mice; Oxotremorine; Parasympathetic Nervous System; Salivation; Time Factors; Tremor | 1983 |
Effect of oral CDP-choline on acrylamide-induced lesion.
Topics: Acrylamide; Acrylamides; Animals; Apomorphine; Body Weight; Choline; Cytidine Diphosphate Choline; Drug Interactions; Eating; Humans; Mice; Nervous System Diseases; Rats; Rats, Inbred Strains; Stereotyped Behavior | 1983 |
CDP-choline: acute toxicity study.
Topics: Administration, Oral; Animals; Choline; Cytidine Diphosphate Choline; Female; Injections, Intravenous; Lethal Dose 50; Male; Mice; Rats; Rats, Inbred Strains; Species Specificity | 1983 |
Study of subacute toxicity of CDP-choline after 30 days of oral administration to rats.
Topics: Administration, Oral; Aging; Animals; Choline; Cytidine Diphosphate Choline; Diet; Eating; Female; Male; Rats; Rats, Inbred Strains; Sex Factors | 1983 |
CDP-choline: 6-month study on toxicity in dogs.
Topics: Animals; Body Weight; Choline; Cytidine Diphosphate Choline; Dogs; Female; Kidney; Liver; Lung; Male; Myocardium; Ovary; Spleen; Testis | 1983 |
Action of CDP-choline by intraduodenal route on rat cardiorespiratory system.
Topics: Animals; Cardiovascular System; Choline; Cytidine Diphosphate Choline; Duodenum; Heart Rate; Hemodynamics; Injections; Male; Rats; Rats, Inbred Strains; Respiration; Respiratory System | 1983 |
Bioavailability of methyl-14C CDP-choline by oral route.
Topics: Administration, Oral; Animals; Biological Availability; Choline; Cytidine Diphosphate Choline; Feces; Injections, Intravenous; Kinetics; Male; Rats; Rats, Inbred Strains | 1983 |
Radioactivity incorporation into different cerebral phospholipids after oral administration of 14C methyl CDP-choline.
Topics: Administration, Oral; Animals; Brain; Choline; Cytidine Diphosphate Choline; Male; Phospholipids; Rats; Rats, Inbred Strains | 1983 |
Low-resolution autoradiography in rat brain after administering labelled CDP-choline.
Topics: Animals; Autoradiography; Brain; Choline; Cytidine Diphosphate Choline; Male; Rats; Rats, Inbred Strains | 1983 |
High-resolution autoradiography in mouse brain 24 h after radiolabelled CDP-choline administration.
Topics: Animals; Autoradiography; Brain; Choline; Cytidine Diphosphate Choline; Mice; Subcellular Fractions | 1983 |
High-resolution autoradiography in mouse brain and cerebellum 10 days after radiolabelled CDP-choline administration.
Topics: Animals; Autoradiography; Brain; Cerebellum; Choline; Cytidine Diphosphate Choline; Mice | 1983 |
Treatment of chronic dyskinesia with CDP-choline.
Topics: Acetylcholine; Choline; Cytidine Diphosphate Choline; Dyskinesia, Drug-Induced; Female; Humans; Middle Aged; Receptors, Dopamine | 1983 |
Efficacy and safety of oral CDP-choline. Drug surveillance study in 2817 cases.
Topics: Administration, Oral; Adolescent; Adult; Aged; Aging; Cerebrovascular Disorders; Child; Choline; Cytidine Diphosphate Choline; Female; Humans; Male; Middle Aged; Sex Factors; Time Factors | 1983 |
The effect of cytidine-diphosphate choline (CDP-choline) on brain lipid changes during aging.
Topics: Aging; Animals; Brain; Carbon Radioisotopes; Choline; Cytidine Diphosphate Choline; Lipid Metabolism; Male; Rats; Rats, Inbred Strains; Tissue Distribution; Tritium | 1984 |
The influence of cytidine on the endogenous pool of CDP-choline, CDP-ethanolamine, and CMP of the rat brain.
Topics: Animals; Brain; Choline; Cytidine; Cytidine Diphosphate; Cytidine Diphosphate Choline; Cytidine Monophosphate; Cytosine Nucleotides; Ethanolamines; Female; Injections, Intraventricular; Kinetics; Male; Rats; Rats, Inbred Strains | 1984 |
Ethanolamine inhibits choline uptake in the isolated hamster heart.
Topics: Animals; Choline; Cricetinae; Cytidine Diphosphate Choline; Ethanolamine; Ethanolamines; Heart; Hemicholinium 3; Male; Mesocricetus; Myocardium; Perfusion; Phosphatidylcholines | 1984 |
[Effect of the administration of nucleotide coenzymes on the lipogenic enzyme changes caused by chronic alcohol intoxication].
Topics: Alcohol Oxidoreductases; Alcoholism; Animals; Choline; Coenzyme A; Cytidine Diphosphate Choline; Dietary Fats; Humans; Lipid Metabolism; Liver; Male; Rats; Rats, Inbred Strains; S-Adenosylmethionine; Uridine Diphosphate Glucose; Uridine Diphosphate Sugars | 1982 |
[CDP-choline in the study of somatotropin function in childhood].
Topics: Adolescent; Child; Child, Preschool; Choline; Cytidine Diphosphate Choline; Female; Growth; Growth Hormone; Humans; Insulin; Male | 1982 |
[Effects of citicholine on pituitary gland function in normal subjects and in cases of idiopathic galactorrhea].
Topics: Adolescent; Adult; Choline; Cimetidine; Cytidine Diphosphate Choline; Female; Galactorrhea; Growth Hormone; Humans; Lactation Disorders; Male; Metoclopramide; Middle Aged; Pituitary Gland; Pregnancy; Prolactin; Thyrotropin; Thyrotropin-Releasing Hormone | 1980 |
The electromyographical effect of CNS metabolism-improving agents in rabbits.
Topics: Adenosine Triphosphate; Animals; Choline; Cytidine Diphosphate Choline; Depression, Chemical; Electromyography; Glycolates; Meclofenoxate; Muscles; Rabbits | 1980 |
Effect of cytidine diphosphate choline (CDP-choline) on ischemia-induced alterations of brain lipid in the gerbil.
Topics: Animals; Arachidonic Acid; Arachidonic Acids; Brain; Carotid Arteries; Choline; Cytidine Diphosphate Choline; Diglycerides; Fatty Acids, Nonesterified; Gerbillinae; Ischemia; Lipid Metabolism; Phosphatidylcholines | 1981 |
[Citicoline activity in senile mental decay].
Topics: Aged; Choline; Cytidine Diphosphate Choline; Dementia; Drug Evaluation; Female; Humans; Injections, Intramuscular; Male; Mental Status Schedule; Time Factors | 1983 |
Effects of CDPcholine and CDPethanolamine on the alterations in rat brain lipid metabolism induced by global ischemia.
Topics: Acetates; Animals; Brain; Brain Ischemia; Choline; Cytidine Diphosphate; Cytidine Diphosphate Choline; Cytosine Nucleotides; Ethanolamines; Fatty Acids, Nonesterified; Kinetics; Lipid Metabolism; Male; Rats; Rats, Inbred Strains | 1983 |
Uptake and utilization of CDP-choline in primary brain cell cultures from fetal brain.
Topics: Animals; Brain; Carbon Radioisotopes; Cells, Cultured; Choline; Cytidine Diphosphate Choline; Female; Fetus; Kinetics; Pregnancy; Rats; Tritium | 1983 |
Phosphatidylcholine biosynthesis in isolated hamster heart.
Topics: Animals; Choline; Cricetinae; Cytidine Diphosphate Choline; Ethanolamines; In Vitro Techniques; Mesocricetus; Myocardium; Perfusion; Phosphatidylcholines; Radioisotope Dilution Technique; Subcellular Fractions; Tritium | 1980 |
Effect of thyroid dysfunction upon phospholipid composition and CDP-choline incorporation in mitochondria and microsomal fraction isolated from liver and brain of suckling rats.
Topics: Animals; Animals, Newborn; Brain; Choline; Cytidine Diphosphate Choline; Hyperthyroidism; Hypothyroidism; Liver; Microsomes; Microsomes, Liver; Mitochondria; Mitochondria, Liver; Organ Specificity; Phospholipids; Rats; Rats, Inbred Strains; Thyroxine | 1982 |
[Transport of cytidinediphosphocholine in different biological models. III. Transport of (5 3H, Met 14C) cytidinediphosphocholine in intact human erythrocytes].
Topics: Biological Transport, Active; Choline; Cytidine Diphosphate Choline; Erythrocytes; Humans; Models, Biological; Time Factors | 1982 |
Inhibition of phosphatidylethanolamine N-methylation by 3-deazaadenosine stimulates the synthesis of phosphatidylcholine via the CDP-choline pathway.
Topics: Animals; Choline; Cytidine Diphosphate Choline; Isomerism; Kinetics; Liver; Male; Methionine; Methylation; Phosphatidylcholines; Phosphatidylethanolamines; Rats; Rats, Inbred Strains; Ribonucleosides; Tubercidin | 1982 |
Drug action on the metabolic changes induced by acute hypoxia on synaptosomes from the cerebral cortex.
Topics: Acute Disease; Animals; Cerebral Cortex; Choline; Cytidine Diphosphate Choline; Dogs; Female; Hypoxia; Oxygen Consumption; Pentobarbital; Synaptosomes | 1982 |
Major phospholipids and phosphatidylcholine synthesis in adult Schistosoma mansoni.
Topics: Animals; Choline; Cytidine Diphosphate Choline; Female; Male; Methylation; Phosphatidylcholines; Phosphatidylethanolamines; Phosphatidylglycerols; Phosphatidylserines; Phospholipids; Schistosoma mansoni | 1982 |
Cellular and enzymic synthesis of sphingomyelin.
Topics: Animals; Cell Membrane; Ceramides; Choline; Cricetinae; Culture Techniques; Cytidine Diphosphate Choline; Kidney; Liver; Phosphatidylcholines; Sphingomyelins; Subcellular Fractions | 1982 |
Control of phosphatidylcholine biosynthesis in myopathic hamster hearts.
Topics: Aging; Animals; Cardiomyopathies; Choline; Cricetinae; Cytidine Diphosphate Choline; Cytidine Triphosphate; Heart; Kinetics; Mesocricetus; Myocardium; Phosphatidylcholines; Reference Values | 1982 |
The rate-limiting step in the biosynthesis of phosphatidylcholine by alveolar type II cells from adult rat lung.
Topics: Animals; Choline; Cytidine Diphosphate Choline; Lung; Phosphatidylcholines; Rats | 1982 |
The influence of CDP-choline on brain lipid metabolism during ischemia.
Topics: Animals; Brain; Brain Ischemia; Choline; Cytidine Diphosphate Choline; Diglycerides; Fatty Acids, Nonesterified; Gerbillinae; Lipid Metabolism | 1982 |
New strategies in the management of Parkinson's disease: a biological approach using a phospholipid precursor (CDP-choline).
Topics: Adult; Aged; Benserazide; Carbidopa; Choline; Cytidine Diphosphate Choline; Dose-Response Relationship, Drug; Double-Blind Method; Drug Therapy, Combination; Female; Humans; Levodopa; Male; Middle Aged; Parkinson Disease; Receptors, Dopamine | 1982 |
[Personal experience in the treatment of placental insufficiency with cytidine diphosphocholine].
Topics: Adult; Choline; Cytidine Diphosphate Choline; Estriol; Female; Humans; Placenta Diseases; Placental Insufficiency; Pregnancy; Trophoblasts | 1980 |
Pulmonary phosphatidylcholine biosynthesis. Alterations in the pool sizes of choline and choline derivatives in rabbit fetal lung during development.
Topics: Animals; Choline; Cytidine Diphosphate Choline; Gestational Age; Lung; Phosphatidylcholines; Phosphorylcholine; Rabbits | 1981 |
Hormonal induction of pulmonary maturation in the rabbit fetus: effects of maternal treatment with estradiol-17 beta on th endogenous levels of cholinephosphate, CDP-choline and phosphatidylcholine.
Topics: Animals; Choline; Cytidine Diphosphate Choline; Estradiol; Female; Fetus; Lung; Maternal-Fetal Exchange; Phosphatidylcholines; Phosphorylcholine; Pregnancy; Rabbits | 1981 |
Effects of CDP-choline on striatal dopamine level and behavior in rats.
Topics: Animals; Behavior, Animal; Choline; Corpus Striatum; Cytidine Diphosphate Choline; Dopamine; Dose-Response Relationship, Drug; Hydroxydopamines; Male; Rats; Receptors, Dopamine | 1981 |
[Transport of cytidinediphosphocholine in different biological models. I - Synthesis and characterization of (5 3H, Met 14 C) cytidinediphosphocholine].
Topics: Carbon Radioisotopes; Choline; Chromatography, Gel; Cytidine Diphosphate Choline; Isotope Labeling; Magnetic Resonance Spectroscopy; Tritium | 1981 |
[Transport of cytidinediphosphocholine in different biological models. II - Transport of (5 3H, Met 14C) cytidinediphosphocholine in isolated and perfused rat liver].
Topics: Animals; Carbon Radioisotopes; Choline; Chromatography, High Pressure Liquid; Cytidine Diphosphate Choline; Liver; Male; Perfusion; Rats; Rats, Inbred Strains; Tritium | 1981 |
Pool sizes of the precursors for phosphatidylcholine synthesis in developing rat lung.
Topics: Animals; Choline; Cytidine Diphosphate Choline; Fatty Acids; Female; Fetus; Glycerol; Lung; Palmitic Acid; Palmitic Acids; Phosphatidylcholines; Pregnancy; Rats; Rats, Inbred Strains | 1981 |
Effect of CDP-choline on the biosynthesis of phospholipids in brain regions during hypoxic treatment.
Topics: Animals; Brain; Carbon Radioisotopes; Choline; Cytidine Diphosphate Choline; Female; Glycerol; Guinea Pigs; Hypoxia; Injections, Intraperitoneal; Injections, Intraventricular; Lipids; Palmitic Acid; Palmitic Acids; Phospholipids; Tritium | 1981 |
Morphological effects of cytidin-diphosphate-choline on rats with lesions of the substantia nigra: study using horse radish peroxidase method.
Topics: Animals; Brain; Choline; Cytidine Diphosphate Choline; Horseradish Peroxidase; Nerve Regeneration; Rats; Rats, Inbred Strains; Substantia Nigra | 1981 |
Pool size of CDP-choline in the brain, heart, and lung of normal hypoxic guinea pigs.
Topics: Animals; Brain; Choline; Cytidine Diphosphate Choline; Female; Guinea Pigs; Hypoxia; Lung; Myocardium | 1981 |
CDPcholine and CDPethanolamine prevent the release of free fatty acids during brain ischemia.
Topics: Animals; Brain; Brain Ischemia; Choline; Cytidine Diphosphate; Cytidine Diphosphate Choline; Cytosine Nucleotides; Ethanolamines; Fatty Acids, Nonesterified; Male; Rats | 1981 |
Differential effect of L-thyroxine on phospholipid biosynthesis in mitochondria and microsomal fraction.
Topics: Animals; Brain; Choline; Cytidine Diphosphate Choline; Female; In Vitro Techniques; Male; Microsomes; Microsomes, Liver; Mitochondria; Mitochondria, Liver; Phosphatidylcholines; Rats; Thyroxine | 1980 |
[Protective effect of citicoline on renal ischemia].
Topics: Animals; Choline; Cytidine Diphosphate Choline; Dogs; Ischemia; Kidney Diseases; Rabbits; Renal Artery Obstruction | 1980 |
Effect of cytidine diphosphate choline on growth hormone secretion in patients with brain or pituitary lesions.
Topics: Adolescent; Adult; Aged; Brain Diseases; Brain Neoplasms; Child; Choline; Cytidine Diphosphate Choline; Female; Frontal Lobe; Growth Hormone; Humans; Hypothalamic Diseases; Hypothalamus; Hypothalamus, Anterior; Hypothalamus, Middle; Male; Middle Aged; Pinealoma; Pituitary Gland; Temporal Lobe | 1980 |
The effect of cytidine diphosphate choline on in vivo lung mechanics in premature newborn rabbits.
Topics: Animals; Animals, Newborn; Biomechanical Phenomena; Body Fluids; Choline; Cytidine Diphosphate Choline; Lung; Phosphatidylcholines; Rabbits; Respiration; Surface Properties | 1980 |
Reciprocal regulation of choline acetyltransferase and choline kinase in sympathetic neurons during cholinergic differentiation.
Topics: Acetylcholine; Animals; Animals, Newborn; Cell Differentiation; Cells, Cultured; Choline; Choline Kinase; Choline O-Acetyltransferase; Cytidine Diphosphate Choline; Ganglia, Sympathetic; Hemicholinium 3; Homeostasis; Neurons; Phosphatidylcholines; Potassium; Rats; Rats, Sprague-Dawley; Sodium; Tretinoin; Tritium | 1995 |
Evidence that 5'-cytidinediphosphocholine can affect brain phospholipid composition by increasing choline and cytidine plasma levels.
Topics: Animals; Brain; Choline; Cytidine; Cytidine Diphosphate Choline; Female; Phosphatidylcholines; Phosphatidylethanolamines; Phosphatidylserines; Phospholipids; Rats; Rats, Sprague-Dawley; Time Factors | 1995 |
Lysophosphatidylcholine and 1-O-octadecyl-2-O-methyl-rac-glycero-3-phosphocholine inhibit the CDP-choline pathway of phosphatidylcholine synthesis at the CTP:phosphocholine cytidylyltransferase step.
Topics: Animals; Antineoplastic Agents; Cell Line; Choline; Choline Kinase; Cytidine Diphosphate Choline; Dose-Response Relationship, Drug; Kinetics; Lysophosphatidylcholines; Macrophages; Mice; Nucleotidyltransferases; Phosphatidylcholines; Phospholipid Ethers; RNA Nucleotidyltransferases | 1995 |
The Saccharomyces cerevisiae phosphatidylinositol-transfer protein effects a ligand-dependent inhibition of choline-phosphate cytidylyltransferase activity.
Topics: Carbon Radioisotopes; Carrier Proteins; Choline; Choline-Phosphate Cytidylyltransferase; Cloning, Molecular; Cytidine Diphosphate Choline; Cytosol; Escherichia coli; Genotype; Golgi Apparatus; Intracellular Membranes; Kinetics; Ligands; Membrane Proteins; Models, Biological; Nucleotidyltransferases; Phosphatidylinositols; Phospholipid Transfer Proteins; Phospholipids; Recombinant Proteins; Saccharomyces cerevisiae; Saccharomyces cerevisiae Proteins | 1995 |
Functional redundancy of CDP-ethanolamine and CDP-choline pathway enzymes in phospholipid biosynthesis: ethanolamine-dependent effects on steady-state membrane phospholipid composition in Saccharomyces cerevisiae.
Topics: Carrier Proteins; Choline; Cytidine Diphosphate; Cytidine Diphosphate Choline; Ethanolamine; Ethanolamines; Genes, Fungal; Inositol; Membrane Proteins; Membranes; Mutation; Phosphatidylcholines; Phosphatidylethanolamines; Phospholipid Transfer Proteins; Saccharomyces cerevisiae; Saccharomyces cerevisiae Proteins | 1994 |
Influence of cyclic AMP on the biosynthesis of phosphatidylcholine in Microsporum gypseum.
Topics: Aminophylline; Atropine; Carbon Radioisotopes; Choline; Cyclic AMP; Cytidine Diphosphate Choline; Ethanolamine; Ethanolamines; Methionine; Microsporum; Phosphatidylcholines | 1993 |
Phosphatidylcholine biosynthesis via the CDP-choline pathway in Saccharomyces cerevisiae. Multiple mechanisms of regulation.
Topics: Base Sequence; Biological Transport; Carrier Proteins; Choline; Choline Kinase; Choline-Phosphate Cytidylyltransferase; Cytidine Diphosphate; Cytidine Diphosphate Choline; Diacylglycerol Cholinephosphotransferase; DNA Primers; Genes, Fungal; Genotype; Homeostasis; Inositol; Kinetics; Membrane Transport Proteins; Molecular Sequence Data; Nucleotidyltransferases; Phosphatidylcholines; Polymerase Chain Reaction; Saccharomyces cerevisiae | 1994 |
Involvement of the lysosome in the catabolism of intracellular lysophosphatidylcholine and evidence for distinct pools of lysophosphatidylcholine.
Topics: Albumins; Animals; Brefeldin A; Chloroquine; Choline; Cyclopentanes; Cytidine Diphosphate Choline; Liver; Lysophosphatidylcholines; Lysosomes; Methionine; Methylation; Phosphatidylcholines; Rats; Tritium | 1993 |
Evidence that the major membrane lipids, except cholesterol, are made in axons of cultured rat sympathetic neurons.
Topics: Acetates; Acetic Acid; Animals; Axons; Carbon Radioisotopes; Cells, Cultured; Cholesterol; Choline; Choline Kinase; Choline-Phosphate Cytidylyltransferase; Cytidine Diphosphate Choline; Diacylglycerol Cholinephosphotransferase; Ethanolamine; Ethanolamines; Inositol; Kinetics; Membrane Lipids; Neurons; Nucleotidyltransferases; Phospholipids; Radioisotope Dilution Technique; Rats; Rats, Sprague-Dawley; S-Adenosylmethionine; Serine; Superior Cervical Ganglion; Tritium | 1994 |
Effect of exogenous CDP-choline on choline metabolism in isolated adult rat ventricular myocytes under normoxic and hypoxic conditions.
Topics: Animals; Choline; Cytidine Diphosphate Choline; Dose-Response Relationship, Drug; Heart Ventricles; Hypoxia; Myocardium; Phosphatidylcholines; Rats; Rats, Wistar | 1993 |
Mechanisms of hepatic phosphatidylcholine synthesis in the developing guinea pig: contributions of acyl remodelling and of N-methylation of phosphatidylethanolamine.
Topics: Animals; Animals, Newborn; Choline; Chromatography, High Pressure Liquid; Cytidine Diphosphate Choline; Ethanolamine; Ethanolamines; Fatty Acids, Unsaturated; Guinea Pigs; Liver; Methionine; Methylation; Microsomes, Liver; Phosphatidylcholines; Phosphatidylethanolamines | 1993 |
The enhancement of phosphatidylcholine biosynthesis by angiotensin II in H9c2 cells.
Topics: Angiotensin II; Animals; Cell Line; Choline; Choline-Phosphate Cytidylyltransferase; Cytidine Diphosphate Choline; Diacylglycerol Cholinephosphotransferase; Diglycerides; Ethers, Cyclic; Myocardium; Nucleotidyltransferases; Okadaic Acid; Phosphatidylcholines; Protein Kinase Inhibitors; Rats | 1995 |
Expression of phosphatidylethanolamine N-methyltransferase-2 in McArdle-RH7777 hepatoma cells inhibits the CDP-choline pathway for phosphatidylcholine biosynthesis via decreased gene expression of CTP:phosphocholine cytidylyltransferase.
Topics: Animals; Cell Division; Choline; Choline-Phosphate Cytidylyltransferase; Cytidine Diphosphate Choline; Gene Expression; Immunoblotting; Liver; Liver Neoplasms, Experimental; Methyltransferases; Nucleotidyltransferases; Phosphatidylcholines; Phosphatidylethanolamine N-Methyltransferase; Phosphatidylethanolamines; Phosphatidylserines; Plasmids; Rats; RNA, Messenger; Transfection; Tritium; Tumor Cells, Cultured | 1995 |
Tight connection between choline transport and phosphatidylcholine synthesis in MDCK cells.
Topics: Animals; Biological Transport, Active; Cell Culture Techniques; Cell Line; Choline; Cytidine Diphosphate Choline; Dogs; Kinetics; Phosphatidylcholines | 1996 |
Differential effect of CDP-choline on brain cytosolic choline levels in younger and older subjects as measured by proton magnetic resonance spectroscopy.
Topics: Adult; Age Factors; Brain Chemistry; Choline; Cytidine Diphosphate Choline; Dose-Response Relationship, Drug; Female; Humans; Magnetic Resonance Spectroscopy; Male; Middle Aged | 1996 |
Overexpression of phosphatidylethanolamine N-methyltransferase 2 in CHO-K1 cells does not attenuate the activity of the CDP-choline pathway for phosphatidylcholine biosynthesis.
Topics: Animals; Blotting, Western; CHO Cells; Choline; Choline-Phosphate Cytidylyltransferase; Cricetinae; Cytidine Diphosphate Choline; Ethanolamine; Ethanolamines; Gene Expression Regulation; Methionine; Methyltransferases; Nucleotidyltransferases; Phosphatidylcholines; Phosphatidylethanolamine N-Methyltransferase; Phospholipids; Serine | 1996 |
Enzymatic production of pyrimidine nucleotides using Corynebacterium ammoniagenes cells and recombinant Escherichia coli cells: enzymatic production of CDP-choline from orotic acid and choline chloride (Part I).
Topics: Carbon-Nitrogen Ligases; Choline; Chromatography, High Pressure Liquid; Corynebacterium; Cytidine Diphosphate Choline; Cytidine Triphosphate; Escherichia coli; Gene Expression Regulation, Enzymologic; Ligases; Orotic Acid; Phosphoribosyl Pyrophosphate; Plasmids; Pyrimidine Nucleotides; Saccharomyces cerevisiae; Substrate Specificity; Uridine Diphosphate; Uridine Monophosphate; Uridine Triphosphate | 1997 |
The antiproliferative effect of hexadecylphosphocholine toward HL60 cells is prevented by exogenous lysophosphatidylcholine.
Topics: Antineoplastic Agents; Apoptosis; Cell Cycle; Cell Division; Cell Survival; Choline; Choline-Phosphate Cytidylyltransferase; Cytidine Diphosphate Choline; DNA Fragmentation; Enzyme Inhibitors; Flow Cytometry; HL-60 Cells; Humans; Lysophosphatidylcholines; Phosphatidylcholines; Phospholipid Ethers; Phospholipids; Phosphorylcholine; Recombinant Proteins | 1998 |
Effect of 27-hydroxycholesterol on cellular sphingomyelin synthesis and Ca++ content in cultured smooth muscle cells.
Topics: Calcium; Cell Survival; Cells, Cultured; Choline; Cytidine Diphosphate Choline; Cytosol; Humans; Hydroxycholesterols; Muscle, Smooth, Vascular; Phosphatidylcholines; Phosphorylcholine; Sphingomyelins | 1997 |
Neutral lipid storage disease: a genetic disorder with abnormalities in the regulation of phospholipid metabolism.
Topics: Cells, Cultured; Choline; Cytidine Diphosphate; Cytidine Diphosphate Choline; Diglycerides; Ethanolamine; Ethanolamines; Fibroblasts; Glycerol; Homeostasis; Humans; Lipid Metabolism, Inborn Errors; Oleic Acid; Phosphatidylcholines; Phosphatidylinositols; Phosphatidylserines; Phospholipids; Sphingomyelins; Triglycerides | 1998 |
Competitive inhibition of choline phosphotransferase by geranylgeraniol and farnesol inhibits phosphatidylcholine synthesis and induces apoptosis in human lung adenocarcinoma A549 cells.
Topics: Actins; Apoptosis; Binding, Competitive; Cell Division; Choline; Choline-Phosphate Cytidylyltransferase; Cytidine Diphosphate Choline; Cytoskeleton; Diacylglycerol Cholinephosphotransferase; Diglycerides; Diterpenes; Enzyme Inhibitors; Farnesol; Humans; Interphase; Microscopy, Fluorescence; Microsomes; Phosphatidylcholines; Protein Prenylation; Tumor Cells, Cultured | 1998 |
Chromatin-associated phosphatidylcholine synthesis.
Topics: Carbon Radioisotopes; Cell Nucleus; Choline; Chromatin; Cytidine Diphosphate Choline; Humans; Neuroblastoma; Phosphatidylcholines; Phosphorylcholine; Tumor Cells, Cultured | 1998 |
Choline derived from the phosphatidylcholine specific phospholipase D is not directly available for the CDP choline pathway in phorbol ester-treated C3H10T1/2 Cl 8 fibroblasts.
Topics: Animals; Cell Line; Choline; Cytidine Diphosphate Choline; Fibroblasts; Indoles; Maleimides; Mice; Mice, Inbred C3H; Phosphatidylcholines; Phospholipase D; Phosphorylcholine; Protein Kinase C; Tetradecanoylphorbol Acetate | 1998 |
Inhibition of phosphatidylcholine biosynthesis following induction of apoptosis in HL-60 cells.
Topics: Alkaloids; Apoptosis; Benzophenanthridines; Camptothecin; Choline; Cytidine Diphosphate Choline; Diacylglycerol Cholinephosphotransferase; Enzyme Inhibitors; Etoposide; Farnesol; Flow Cytometry; HL-60 Cells; Humans; Hydrogen-Ion Concentration; Phenanthridines; Phosphatidylcholines; Phosphorylcholine | 1999 |
Choline release and inhibition of phosphatidylcholine synthesis precede excitotoxic neuronal death but not neurotoxicity induced by serum deprivation.
Topics: Animals; Blood; Cell Death; Cells, Cultured; Cerebellum; Cerebral Cortex; Choline; Cytidine Diphosphate Choline; Glutamic Acid; Hydrolysis; Membrane Lipids; N-Methylaspartate; Necrosis; Neurons; Phosphatidylcholines; Phospholipids; Rats; Rats, Sprague-Dawley; Receptors, N-Methyl-D-Aspartate | 2000 |
Effect of CDP-choline on brain acetylcholinesterase and Na(+), K(+)-ATPase in adult rats.
Topics: Acetylcholine; Acetylcholinesterase; Adenosine Triphosphatases; Animals; Brain; Ca(2+) Mg(2+)-ATPase; Choline; Cytidine; Cytidine Diphosphate Choline; Dose-Response Relationship, Drug; Female; Male; Norepinephrine; Rats; Rats, Wistar; Sodium-Potassium-Exchanging ATPase; Swine; Time Factors | 2000 |
Acceleration of phosphatidylcholine synthesis and breakdown by inhibitors of mitochondrial function in neuronal cells: a model of the membrane defect of Alzheimer's disease.
Topics: Alzheimer Disease; Animals; Carbonyl Cyanide m-Chlorophenyl Hydrazone; Choline; Cytidine Diphosphate Choline; Dinitrophenols; Disease Models, Animal; Dose-Response Relationship, Drug; Enzyme Inhibitors; Glycerylphosphorylcholine; Membranes; Mitochondria; Neurons; PC12 Cells; Phosphatidylcholines; Phosphorylcholine; Rats; Sodium Azide; Time Factors; Uncoupling Agents | 2000 |
Phosphatidylcholine metabolism in nuclei of phorbol ester-activated LA-N-1 neuroblastoma cells.
Topics: Carbon Radioisotopes; Cell Nucleus; Choline; Choline Kinase; Cytidine Diphosphate Choline; Humans; Kinetics; Neuroblastoma; Palmitic Acid; Phosphatidylcholines; Phosphorylcholine; Tetradecanoylphorbol Acetate; Tritium; Tumor Cells, Cultured | 2000 |
Choline deficiency induced by Mycoplasma fermentans enhances apoptosis of rat astrocytes.
Topics: Animals; Apoptosis; Astrocytes; Biological Transport, Active; Choline; Chromatography, Thin Layer; Culture Media; Cytidine Diphosphate Choline; Hot Temperature; Kinetics; Mycoplasma fermentans; Phosphorylcholine; Rats | 2001 |
Cardiovascular effects of intracerebroventricularly injected CDP-choline in normotensive and hypotensive animals: the involvement of cholinergic system.
Topics: Animals; Antidiuretic Hormone Receptor Antagonists; Blood Pressure; Catecholamines; Cerebral Ventricles; Choline; Cholinergic Antagonists; Cytidine Diphosphate Choline; Dose-Response Relationship, Drug; Female; Heart Rate; Hypotension; Hypothalamus; Injections, Intraventricular; Male; Rats; Rats, Wistar; Shock, Hemorrhagic; Time Factors; Vasopressins | 2002 |
Intravenously injected CDP-choline increases blood pressure and reverses hypotension in haemorrhagic shock: effect is mediated by central cholinergic activation.
Topics: Animals; Blood Pressure; Brain; Catecholamines; Choline; Cytidine Diphosphate Choline; Dose-Response Relationship, Drug; Hypotension; Injections, Intravenous; Male; Nootropic Agents; Rats; Rats, Wistar; Receptors, Nicotinic; Shock, Hemorrhagic; Vasopressins | 2003 |
The cytidine diphosphate choline content of rat brain.
Topics: Brain; Choline; Cytidine Diphosphate Choline; Inactivation, Metabolic; Nucleosides; Nucleotides | 1961 |
Biosynthesis of lecithin in brain. Participation of cytidine diphosphate choline and phosphatidic acid.
Topics: Brain; Choline; Cytidine Diphosphate Choline; Cytosine Nucleotides; Lecithins; Phosphatidic Acids; Phosphatidylcholines; Phospholipids | 1963 |
[EXPERIMENTAL AND CLINICAL STUDIES ON CDP-CHOLINE THERAPY FOR BRAIN INJURIES].
Topics: Animals; Biomedical Research; Brain Injuries; Choline; Cytidine Diphosphate Choline; Lagomorpha; Nucleotides; Rabbits; Research | 1964 |
[TREATMENT OF HEAD INJURIES WITH INTERMEDIATE SUBSTANCES OF THE METABOLIC CYCLE OF THE BRAIN. 1. THE USE OF CDP-CHOLINE].
Topics: Adolescent; Biomedical Research; Brain; Brain Chemistry; Brain Neoplasms; Choline; Craniocerebral Trauma; Cytidine Diphosphate Choline; Cytosine Nucleotides; Drug Therapy; Electroencephalography; Humans; Meningeal Neoplasms; Meningioma; Metabolism; Pharmacology | 1964 |
A choline-deficient diet in mice inhibits neither the CDP-choline pathway for phosphatidylcholine synthesis in hepatocytes nor apolipoprotein B secretion.
Topics: Albumins; Animals; Apolipoproteins B; Calnexin; Centrifugation, Density Gradient; Choline; Choline Deficiency; Culture Media; Cytidine Diphosphate Choline; Hepatocytes; Immunoblotting; Lipoproteins; Liver; Male; Methyltransferases; Mice; Mice, Inbred C57BL; Mice, Transgenic; Phosphatidylcholines; Phosphatidylethanolamine N-Methyltransferase; Phosphorylcholine; Protein Disulfide-Isomerases; Time Factors; Triglycerides | 2004 |
Unraveling the mode of action of the antimalarial choline analog G25 in Plasmodium falciparum and Saccharomyces cerevisiae.
Topics: Animals; Antimalarials; Carboxy-Lyases; Choline; Cytidine Diphosphate Choline; Erythrocytes; Humans; Mutation; Phosphatidylcholines; Phosphatidylethanolamines; Phosphatidylserines; Phospholipids; Plasmodium falciparum; Recombinant Proteins; Saccharomyces cerevisiae | 2004 |
Stachybotrys chartarum alters surfactant-related phospholipid synthesis and CTP:cholinephosphate cytidylyltransferase activity in isolated fetal rat type II cells.
Topics: Animals; Cell Separation; Cells, Cultured; Choline; Choline-Phosphate Cytidylyltransferase; Chromatography, High Pressure Liquid; Cytidine Diphosphate Choline; Cytosol; Female; Fetus; Phosphatidylcholines; Phospholipids; Pregnancy; Rats; Rats, Sprague-Dawley; Spores, Fungal; Stachybotrys; Surface-Active Agents | 2005 |
CDP-choline liposomes provide significant reduction in infarction over free CDP-choline in stroke.
Topics: Animals; Brain; Brain Infarction; Brain Ischemia; Cholesterol; Choline; Cytidine Diphosphate Choline; Disease Models, Animal; Drug Combinations; Drug Synergism; G(M1) Ganglioside; Liposomes; Male; Phagocytosis; Phosphatidylcholines; Rats; Rats, Inbred SHR; Reperfusion Injury; Stroke; Treatment Outcome | 2005 |
Glycerophosphocholine catabolism as a new route for choline formation for phosphatidylcholine synthesis by the Kennedy pathway.
Topics: Biochemistry; Choline; Cytidine Diphosphate Choline; Fatty Acids; Genotype; Glucose; Glycerylphosphorylcholine; Inositol; Models, Chemical; Open Reading Frames; Phosphates; Phosphatidylcholines; Phosphoric Diester Hydrolases; Protein Structure, Tertiary; Saccharomyces cerevisiae; Saccharomyces cerevisiae Proteins; Temperature; Time Factors | 2005 |
Choline induces transcriptional repression and proteasomal degradation of the malarial phosphoethanolamine methyltransferase.
Topics: Animals; Boronic Acids; Bortezomib; Choline; Cytidine Diphosphate Choline; Gene Expression Regulation; Methyltransferases; Plasmodium falciparum; Protease Inhibitors; Proteasome Endopeptidase Complex; Proteasome Inhibitors; Protein Biosynthesis; Protozoan Proteins; Pyrazines; Transcription, Genetic | 2007 |
Cardiovascular effects of CDP-choline and its metabolites: involvement of peripheral autonomic nervous system.
Topics: Adrenal Glands; Adrenalectomy; Animals; Aorta, Thoracic; Autonomic Nervous System; Blood Pressure; Catecholamines; Choline; Cytidine; Cytidine Diphosphate Choline; Cytidine Monophosphate; Heart Atria; Heart Rate; In Vitro Techniques; Male; Nootropic Agents; Parasympathetic Nervous System; Peripheral Nerves; Phosphorylcholine; Rats; Rats, Wistar; Renin; Sympathectomy, Chemical; Vasopressins | 2007 |
Peripheral administration of CDP-choline and its cholinergic metabolites increases serum insulin: muscarinic and nicotinic acetylcholine receptors are both involved in their actions.
Topics: Acetylcholine; Adrenergic alpha-Antagonists; Animals; Choline; Cytidine Diphosphate Choline; Dose-Response Relationship, Drug; Female; Insulin; Insulin Secretion; Islets of Langerhans; Nicotinic Antagonists; Phosphorylcholine; Rats; Rats, Wistar; Reaction Time; Receptors, Adrenergic, alpha; Receptors, Cholinergic; Receptors, Muscarinic; Receptors, Nicotinic; Synaptic Transmission; Up-Regulation | 2008 |
Peripheral administration of CDP-choline, phosphocholine or choline increases plasma adrenaline and noradrenaline concentrations.
Topics: Adrenal Glands; Animals; Atropine Derivatives; Autonomic Nervous System; Central Nervous System; Choline; Cytidine; Cytidine Diphosphate Choline; Cytidine Monophosphate; Disease Models, Animal; Dose-Response Relationship, Drug; Epinephrine; Female; Hemorrhage; Hexamethonium; Injections, Intraperitoneal; Injections, Intraventricular; Mecamylamine; Nicotinic Antagonists; Norepinephrine; Phosphorylcholine; Rats; Rats, Wistar; Time Factors | 2008 |
CDP-choline prevents cardiac arrhythmias and lethality induced by short-term myocardial ischemia-reperfusion injury in the rat: involvement of central muscarinic cholinergic mechanisms.
Topics: Acetylcholine; Anesthesia; Animals; Anti-Arrhythmia Agents; Atropine; Blood Pressure; Choline; Chromatography, High Pressure Liquid; Cytidine Diphosphate Choline; Electrocardiography; Injections, Intraventricular; Male; Microdialysis; Muscarinic Antagonists; Myocardial Reperfusion Injury; Nootropic Agents; Rats; Receptors, Muscarinic; Survival Analysis; Vagotomy | 2008 |
Central choline suppresses plasma renin response to graded haemorrhage in rats.
Topics: Animals; Antihypertensive Agents; Blood Pressure; Carbachol; Choline; Cholinergic Agonists; Cholinesterase Inhibitors; Cytidine Diphosphate Choline; Dose-Response Relationship, Drug; Drug Interactions; Female; Hemorrhage; Injections, Intraventricular; Mecamylamine; Periodicity; Physostigmine; Rats; Rats, Wistar; Renin; Renin-Angiotensin System; Vasopressins | 2008 |
Choline, CDP-choline or phosphocholine increases plasma glucagon in rats: involvement of the peripheral autonomic nervous system.
Topics: Adrenal Medulla; Adrenalectomy; Adrenergic alpha-Antagonists; Adrenergic beta-Antagonists; Animals; Autonomic Nervous System; Brain; Choline; Cytidine Diphosphate Choline; Dose-Response Relationship, Drug; Ganglionic Blockers; Glucagon; Injections, Intraperitoneal; Injections, Intraventricular; Male; Muscarinic Antagonists; Neurotransmitter Uptake Inhibitors; Nicotinic Antagonists; Phosphorylcholine; Rats; Rats, Sprague-Dawley; Sympathectomy, Chemical; Time Factors; Up-Regulation | 2008 |
Choline or CDP-choline alters serum lipid responses to endotoxin in dogs and rats: involvement of the peripheral nicotinic acetylcholine receptors.
Topics: Animals; Atropine; Cholesterol; Choline; Cytidine Diphosphate Choline; Dogs; Endotoxins; Fatty Acids, Nonesterified; Female; Hexamethonium; Kidney; Lipid Metabolism; Lipids; Liver; Male; Nicotinic Antagonists; Phospholipids; Rats; Rats, Wistar; Receptors, Nicotinic; Shock, Septic; Triglycerides | 2009 |
Choline or CDP-choline attenuates coagulation abnormalities and prevents the development of acute disseminated intravascular coagulation in dogs during endotoxemia.
Topics: Animals; Blood Coagulation; Choline; Cytidine Diphosphate Choline; Disseminated Intravascular Coagulation; Dogs; Endotoxemia; Endotoxins; Female; Male | 2010 |
Specificity and rate of human and mouse liver and plasma phosphatidylcholine synthesis analyzed in vivo.
Topics: Adult; Animals; Choline; Cytidine Diphosphate Choline; Deuterium; Female; Humans; Liver; Lung; Male; Mice; Phosphatidylcholines; Phosphatidylethanolamine N-Methyltransferase | 2011 |
Effect of choline-containing phospholipids on brain cholinergic transporters in the rat.
Topics: Animals; Blotting, Western; Brain Chemistry; Carrier Proteins; Choline; Chromatography, High Pressure Liquid; Cytidine Diphosphate Choline; Enzyme-Linked Immunosorbent Assay; Glycerylphosphorylcholine; Immunohistochemistry; Membrane Transport Proteins; Nootropic Agents; Parasympathetic Nervous System; Phospholipids; Rats; Rats, Wistar; Reference Standards; Synaptic Transmission; Vesicular Acetylcholine Transport Proteins | 2011 |
CDP-choline and its endogenous metabolites, cytidine and choline, promote the nerve regeneration and improve the functional recovery of injured rat sciatic nerves.
Topics: Administration, Cutaneous; Animals; Choline; Cytidine; Cytidine Diphosphate Choline; Disease Models, Animal; Female; Nerve Regeneration; Neuroprotective Agents; Rats; Rats, Sprague-Dawley; Recovery of Function; Sciatic Neuropathy; Trauma Severity Indices | 2011 |
The antihyperalgesic effect of cytidine-5'-diphosphate-choline in neuropathic and inflammatory pain models.
Topics: alpha7 Nicotinic Acetylcholine Receptor; Analgesics; Animals; Choline; Cytidine Diphosphate Choline; Disease Models, Animal; Dose-Response Relationship, Drug; Hyperalgesia; Inflammation; Male; Neuralgia; Pain; Rats; Rats, Sprague-Dawley; Receptors, GABA-B; Receptors, Nicotinic; Receptors, Opioid; Time Factors | 2011 |
Intraperitoneal administration of CDP-choline or a combination of cytidine plus choline improves nerve regeneration and functional recovery in a rat model of sciatic nerve injury.
Topics: Animals; Axotomy; Choline; Cytidine; Cytidine Diphosphate Choline; Disease Models, Animal; Drug Therapy, Combination; Female; Injections, Intraperitoneal; Nerve Regeneration; Nootropic Agents; Rats; Rats, Sprague-Dawley; Recovery of Function; Sciatic Nerve; Sciatic Neuropathy | 2012 |
Modulation of monoaminergic transporters by choline-containing phospholipids in rat brain.
Topics: Animals; Brain; Choline; Cytidine Diphosphate Choline; Glycerylphosphorylcholine; Phospholipids; Random Allocation; Rats; Rats, Wistar; Vesicular Monoamine Transport Proteins | 2013 |
Pivotal role of choline metabolites in remyelination.
Topics: Animals; Cell Proliferation; Chelating Agents; Choline; Cuprizone; Cytidine Diphosphate Choline; Demyelinating Diseases; Mice; Mice, Inbred C57BL; Myelin Sheath; Neural Stem Cells; Neuroglia; Nootropic Agents; Oligodendroglia; Rats; Rats, Sprague-Dawley; T-Lymphocytes | 2015 |
Methionine and choline supply alter transmethylation, transsulfuration, and cytidine 5'-diphosphocholine pathways to different extents in isolated primary liver cells from dairy cows.
Topics: Animals; Betaine-Homocysteine S-Methyltransferase; Cattle; Cells, Cultured; Choline; Cytidine Diphosphate Choline; Diet; Dietary Supplements; Female; Hepatocytes; Lactation; Liver; Methionine; Milk Proteins; Parturition; Pregnancy | 2018 |
CDP-choline accumulation in breast and colorectal cancer cells treated with a GSK-3-targeting inhibitor.
Topics: Biomarkers, Tumor; Breast Neoplasms; Cell Line, Tumor; Choline; Colorectal Neoplasms; Cytidine Diphosphate Choline; Enzyme Inhibitors; Female; Glucose; Glycogen Synthase Kinase 3; Humans; Indoles; Lipid Metabolism; Magnetic Resonance Spectroscopy; Maleimides; Phosphatidylcholines | 2019 |
A novel approach in the management of hyperhomocysteinemia.
Topics: Alcohol Oxidoreductases; Animals; Choline; Cytidine Diphosphate Choline; Dietary Supplements; Endothelial Cells; Folic Acid; Homocysteine; Humans; Hydrolysis; Hyperhomocysteinemia; Kidney; Life Style; Liver; Methionine; Models, Theoretical; Vitamin B 12; Vitamin B 6 | 2019 |
Engineering substrate and energy metabolism for living cell production of cytidine-5'-diphosphocholine.
Topics: Adenosine Triphosphate; Choline; Cytidine Diphosphate Choline; Energy Metabolism; Metabolic Engineering; Saccharomycetales | 2020 |
[A personalized selection of choline precursors in evidence - based medicine].
Topics: Brain Ischemia; Choline; Cytidine Diphosphate Choline; Humans; Neuroprotective Agents; Nootropic Agents | 2020 |
Choline or CDP-choline restores hypotension and improves myocardial and respiratory functions in dogs with experimentally - Induced endotoxic shock.
Topics: Animals; Choline; Cytidine Diphosphate Choline; Dog Diseases; Dogs; Hypotension; Myocardium; Shock, Septic | 2021 |
Role of citicoline and choline in the treatment of post-stroke depression: an exploratory study.
Topics: Choline; Cytidine Diphosphate Choline; Depression; Humans; Retrospective Studies; Selective Serotonin Reuptake Inhibitors | 2021 |
Choline and citicoline ameliorate oxidative stress in acute kidney injury in rats.
Topics: Acute Kidney Injury; Animals; Choline; Cytidine Diphosphate Choline; Endotoxemia; Kidney; Lipopolysaccharides; NADP; NF-kappa B; Oxidative Stress; Rats; Reactive Oxygen Species | 2023 |
Structural basis for catalysis of human choline/ethanolamine phosphotransferase 1.
Topics: Catalysis; Choline; Cytidine Diphosphate Choline; Ethanolamines; Humans; Phosphatidylcholines; Phosphotransferases | 2023 |
CDP-choline modulates cholinergic signaling and gut microbiota to alleviate DSS-induced inflammatory bowel disease.
Topics: Acetylcholine; Acetylcholinesterase; Animals; Choline; Colitis; Colon; Cytidine Diphosphate Choline; Dextran Sulfate; Disease Models, Animal; Gastrointestinal Microbiome; Humans; Inflammation; Inflammatory Bowel Diseases; Mice; Mice, Inbred C57BL; Nicotinic Antagonists | 2023 |