Compounds > cytidine
Page last updated: 2024-08-17

cytidine and psi 6130

cytidine has been researched along with psi 6130 in 6 studies

Research

Studies (6)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's5 (83.33)29.6817
2010's1 (16.67)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Bao, H; Furman, PA; McBrayer, TR; Micolochick Steuer, HM; Murakami, E; Obikhod, A; Otto, MJ; Ramesh, M; Schinazi, RF; Stuyver, LJ; Whitaker, T1
Bao, H; Furman, PA; Micolochick Steuer, HM; Murakami, E; Nachman, T; Niu, C; Otto, MJ; Sofia, MA; Wang, P; Whitaker, T1
Ali, S; Cammack, N; Jiang, WR; Kang, H; Le Pogam, S; McCown, MF; Najera, I; Rajyaguru, S; Symons, J1
Bassit, L; Bennett, M; Grier, J; Schinazi, RF1
Ali, S; Alker, A; Cammack, N; Inocencio, N; Jiang, WR; Kang, H; Klumpp, K; Le Pogam, S; Leveque, V; Ma, H; Najera, I; Philipp, F; Smith, M; Symons, J1
Barclay, L; Costantini, VP; Lee, D; McBrayer, TR; Schinazi, RF; Vinjé, J; Whitaker, T1

Other Studies

6 other study(ies) available for cytidine and psi 6130

ArticleYear
Mechanism of activation of beta-D-2'-deoxy-2'-fluoro-2'-c-methylcytidine and inhibition of hepatitis C virus NS5B RNA polymerase.
    Antimicrobial agents and chemotherapy, 2007, Volume: 51, Issue:2

    Topics: Antiviral Agents; Catalysis; Deoxycytidine; Hepacivirus; Hepatitis C; Humans; Mutation; Phosphorylation; RNA-Dependent RNA Polymerase; RNA, Viral; Structure-Activity Relationship; Viral Nonstructural Proteins; Virus Replication

2007
The mechanism of action of beta-D-2'-deoxy-2'-fluoro-2'-C-methylcytidine involves a second metabolic pathway leading to beta-D-2'-deoxy-2'-fluoro-2'-C-methyluridine 5'-triphosphate, a potent inhibitor of the hepatitis C virus RNA-dependent RNA polymerase.
    Antimicrobial agents and chemotherapy, 2008, Volume: 52, Issue:2

    Topics: Antiviral Agents; Cell Line; Cytidine; Deoxycytidine; Hepacivirus; Humans; Microbial Sensitivity Tests; Phosphorylation; Replicon; RNA-Dependent RNA Polymerase; Structure-Activity Relationship; Uridine Triphosphate

2008
The hepatitis C virus replicon presents a higher barrier to resistance to nucleoside analogs than to nonnucleoside polymerase or protease inhibitors.
    Antimicrobial agents and chemotherapy, 2008, Volume: 52, Issue:5

    Topics: Antiviral Agents; Cytidine; Deoxycytidine; Drug Resistance, Viral; Hepacivirus; Nucleosides; Oligopeptides; Protease Inhibitors; Replicon; Serine Endopeptidases; Viral Nonstructural Proteins; Virus Replication

2008
Combinations of 2'-C-methylcytidine analogues with interferon-alpha2b and triple combination with ribavirin in the hepatitis C virus replicon system.
    Antiviral chemistry & chemotherapy, 2008, Volume: 19, Issue:1

    Topics: Antiviral Agents; Cells, Cultured; Computer Simulation; Cytidine; Deoxycytidine; Drug Synergism; Drug Therapy, Combination; Hepacivirus; Humans; Interferon alpha-2; Interferon-alpha; Models, Chemical; Monte Carlo Method; Polymerase Chain Reaction; Recombinant Proteins; Replicon; Ribavirin; RNA, Ribosomal; RNA, Viral

2008
Selected replicon variants with low-level in vitro resistance to the hepatitis C virus NS5B polymerase inhibitor PSI-6130 lack cross-resistance with R1479.
    Antimicrobial agents and chemotherapy, 2008, Volume: 52, Issue:12

    Topics: Antiviral Agents; Cell Line; Cytidine; Deoxycytidine; Drug Resistance, Viral; Genetic Variation; Hepacivirus; Humans; Molecular Sequence Data; Replicon; RNA-Dependent RNA Polymerase; Sequence Analysis, DNA; Viral Nonstructural Proteins

2008
Antiviral activity of nucleoside analogues against norovirus.
    Antiviral therapy, 2012, Volume: 17, Issue:6

    Topics: Animals; Antiviral Agents; Cell Line, Tumor; Cytidine; Deoxycytidine; Dose-Response Relationship, Drug; Drug Evaluation, Preclinical; Drug Synergism; Gastroenteritis; Humans; Lamivudine; Mice; Norovirus; Ribavirin; RNA, Viral; Time Factors; Virus Replication

2012