cytidine has been researched along with gemcitabine in 20 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 3 (15.00) | 18.2507 |
| 2000's | 9 (45.00) | 29.6817 |
| 2010's | 5 (25.00) | 24.3611 |
| 2020's | 3 (15.00) | 2.80 |
| Authors | Studies |
|---|---|
| Bao, H; Furman, PA; McBrayer, TR; Micolochick Steuer, HM; Murakami, E; Obikhod, A; Otto, MJ; Ramesh, M; Schinazi, RF; Stuyver, LJ; Whitaker, T | 1 |
| Chubb, S; Grindey, GB; Heinemann, V; Hertel, LW; Plunkett, W; Sen, A; Xu, YZ | 1 |
| Bianchi, V; Borella, S; Calderazzo, F; Chieco Bianchi, L; Ferraro, P; Reichard, P | 1 |
| Cory, AH; Cory, JG; Hertel, LW; Kroin, JS | 1 |
| Casado, FJ; Inzillo, SM; Larrayoz, IM; Lostao, MP; Mata, JF; Pastor-Anglada, M | 1 |
| Leen, R; Van Gennip, AH; Van Kuilenburg, AB; Verschuur, AC | 1 |
| Fujioka, A; Fukushima, M; Kazuno, H; Matsuda, A; Sakamoto, K; Sasaki, T | 1 |
| Bierau, J; Caron, HN; Leen, R; Meinsma, R; van Gennip, AH; van Kuilenburg, AB | 1 |
| Fujimoto, S; Hotta, A; Koma, M; Nagai, K; Nagasawa, K | 1 |
| Leen, R; Medema, J; Rodermond, H; van Bree, C; van Kuilenburg, A | 1 |
| Barten-Van Rijbroek, AD; Kal, HB; Leen, R; Rodermond, HM; Van Bree, C; Van Kuilenburg, AB | 1 |
| Bao, J; Bender, DM; Dantzig, AH; Diseroad, WD; Law, KL; Magnus, NA; McCarthy, JR; Perkins, EJ; Peterson, JA; Pu, YJ; Remick, DM; Reutzel-Edens, SM; Starling, JJ; Stephenson, GA; Vaid, RK; Zhang, D | 1 |
| Ahn, CH; Fine, T; Kashi, R; Kaye, J; Kim, DJ; Lee, YB; Ohne, O; Peters, GJ; Smid, K; Yang, MY | 1 |
| Terui, Y | 1 |
| Honeywell, RJ; Kathmann, I; Kristensen, MH; Peters, GJ; Sarkisjan, D | 1 |
| Coe, IR; Naydenova, Z; Zafar, M | 1 |
| Balboni, B; Benaim, E; El Hassouni, B; Giovannetti, E; Heaton, C; Honeywell, RJ; Kim, DJ; Lee, YB; Peters, GJ; Peterson, C; Poore, J; Sarkisjan, D | 1 |
| Choi, BS; Choi, MS; Kim, DE; Kim, HG; Kim, K; Park, CM; Shin, Y; Yoon, CH | 1 |
| Leung, E; Lozano Hernandez, L; Reginald-Opara, JN; Svirskis, D; Tang, M; Wang, H; Wu, Z | 1 |
| Bhutkar, S; Dukhande, V; Patel, K; Patki, M; Saraswat, A | 1 |
1 review(s) available for cytidine and gemcitabine
| Article | Year |
|---|---|
RX-3117 (fluorocyclopentenyl cytosine): a novel specific antimetabolite for selective cancer treatment.
Topics: Administration, Oral; Antimetabolites, Antineoplastic; Biological Availability; Cytidine; Deoxycytidine; Gemcitabine; Humans; Neoplasms; Patient Selection | 2019 |
19 other study(ies) available for cytidine and gemcitabine
| Article | Year |
|---|---|
Mechanism of activation of beta-D-2'-deoxy-2'-fluoro-2'-c-methylcytidine and inhibition of hepatitis C virus NS5B RNA polymerase.
Topics: Antiviral Agents; Catalysis; Deoxycytidine; Hepacivirus; Hepatitis C; Humans; Mutation; Phosphorylation; RNA-Dependent RNA Polymerase; RNA, Viral; Structure-Activity Relationship; Viral Nonstructural Proteins; Virus Replication | 2007 |
Inhibition of ribonucleotide reduction in CCRF-CEM cells by 2',2'-difluorodeoxycytidine.
Topics: Cell Line; Cytidine; Deoxycytidine; Deoxycytosine Nucleotides; DNA; Gemcitabine; Humans; Hydroxyurea; Oxidation-Reduction; Ribonucleoside Diphosphate Reductase; Ribonucleotides; Thymine Nucleotides | 1990 |
Inhibition of ribonucleotide reductase by 2'-substituted deoxycytidine analogs: possible application in AIDS treatment.
Topics: Acquired Immunodeficiency Syndrome; Antiviral Agents; Cells, Cultured; Cytidine; Deoxycytidine; Gemcitabine; Humans; Hydroxyurea; In Vitro Techniques; Prodrugs; Ribonucleotide Reductases; Zidovudine | 1994 |
Effects of 2',2'-difluorodeoxycytidine (Gemcitabine) on wild type and variant mouse leukemia L1210 cells.
Topics: Animals; Antimetabolites, Antineoplastic; Carbon Radioisotopes; Cytidine; Deoxycytidine; Gemcitabine; Leukemia L1210; Mice; Ribonucleotide Reductases; Tumor Cells, Cultured | 1993 |
Electrogenic uptake of nucleosides and nucleoside-derived drugs by the human nucleoside transporter 1 (hCNT1) expressed in Xenopus laevis oocytes.
Topics: Animals; Antimetabolites, Antineoplastic; Antineoplastic Agents; Antiviral Agents; Carrier Proteins; Cytidine; Deoxycytidine; Electric Conductivity; Gemcitabine; Gene Expression; Humans; Membrane Potentials; Membrane Proteins; Nucleoside Transport Proteins; Nucleosides; Oocytes; Sodium; Substrate Specificity; Uridine; Vidarabine; Xenopus laevis | 2000 |
Increased cytotoxicity of 2',2'-difluoro-2'-deoxycytidine in human leukemic cell-lines after a preincubation with cyclopentenyl cytosine.
Topics: Antimetabolites, Antineoplastic; Antineoplastic Agents; Apoptosis; Carbon-Nitrogen Ligases; Cell Line, Tumor; Cell Separation; Clinical Trials as Topic; Cytidine; Deoxycytidine; DNA; Dose-Response Relationship, Drug; Flow Cytometry; Gemcitabine; HL-60 Cells; Humans; Necrosis; Neoplasms; Time Factors | 2004 |
Possible antitumor activity of 1-(3-C-ethynyl-beta-D-ribo-pentofuranosyl)cytosine (ECyd, TAS-106) against an established gemcitabine (dFdCyd)-resistant human pancreatic cancer cell line.
Topics: Animals; Antineoplastic Agents; Cell Line, Tumor; Cytidine; Deoxycytidine; Deoxyribonucleotides; Drug Resistance, Neoplasm; Gemcitabine; Humans; Inhibitory Concentration 50; Male; Mice; Mice, Nude; Pancreatic Neoplasms; Ribonucleotides; RNA, Messenger; Xenograft Model Antitumor Assays | 2005 |
Cyclopentenyl cytosine-induced activation of deoxycytidine kinase increases gemcitabine anabolism and cytotoxicity in neuroblastoma.
Topics: Antineoplastic Agents; Cell Differentiation; Cell Line, Tumor; Cell Survival; Cytidine; Deoxycytidine; Deoxycytidine Kinase; Dose-Response Relationship, Drug; Drug Synergism; Enzyme Activation; Gemcitabine; Humans; Immunoblotting; N-Myc Proto-Oncogene Protein; Neuroblastoma; Nuclear Proteins; Oncogene Proteins | 2006 |
Cytidine is a novel substrate for wild-type concentrative nucleoside transporter 2.
Topics: Amino Acid Substitution; Animals; Antimetabolites, Antineoplastic; Biological Transport; Chlorocebus aethiops; COS Cells; Cytarabine; Cytidine; Deoxycytidine; Dose-Response Relationship, Drug; Gemcitabine; Genotype; Kinetics; Male; Membrane Transport Proteins; Mice; Thymidine; Transfection; Tritium; Uridine | 2006 |
Cyclopentenyl cytosine increases gemcitabine radiosensitisation in human pancreatic cancer cells.
Topics: Apoptosis; Cell Line, Tumor; Cell Survival; Cytidine; Cytidine Triphosphate; Deoxycytidine; Dose-Response Relationship, Drug; Drug Resistance, Neoplasm; Drug Screening Assays, Antitumor; Drug Synergism; Gemcitabine; Humans; Lung Neoplasms; Pancreatic Neoplasms; Radiation Tolerance; Radiation-Sensitizing Agents | 2008 |
Cyclopentenyl cytosine has biological and anti-tumour activity, but does not enhance the efficacy of gemcitabine and radiation in two animal tumour models.
Topics: Animals; Antineoplastic Combined Chemotherapy Protocols; Cell Line, Tumor; Combined Modality Therapy; Cytidine; Cytidine Triphosphate; Deoxycytidine; Disease Models, Animal; Drug Synergism; Female; Gemcitabine; Humans; Lung Neoplasms; Mice; Mice, Nude; Middle Aged; Pancreatic Neoplasms; Rats; Rats, Inbred BN | 2009 |
Synthesis, crystallization, and biological evaluation of an orally active prodrug of gemcitabine.
Topics: Administration, Oral; Animals; Antineoplastic Agents; Cell Line, Tumor; Cell Transformation, Neoplastic; Colonic Neoplasms; Crystallization; Crystallography, X-Ray; Cytidine; Deoxycytidine; Gemcitabine; Humans; Mice; Models, Molecular; Molecular Conformation; Prodrugs; Solubility | 2009 |
A novel cytidine analog, RX-3117, shows potent efficacy in xenograft models, even in tumors that are resistant to gemcitabine.
Topics: Administration, Oral; Animals; Antimetabolites, Antineoplastic; Cell Line, Tumor; Cytidine; Deoxycytidine; Disease Models, Animal; Drug Resistance, Neoplasm; Female; Gemcitabine; HCT116 Cells; HT29 Cells; Humans; Mice; Mice, Nude; Neoplasms; Xenograft Model Antitumor Assays | 2014 |
[Cytidine].
Topics: Antineoplastic Agents; Arabinonucleosides; Cytarabine; Cytidine; Deoxycytidine; Gemcitabine; Humans; Neoplasms | 2015 |
Sensitive liquid chromatography mass spectrometry (LC-MS) assay reveals novel insights on DNA methylation and incorporation of gemcitabine, its metabolite difluorodeoxyuridine, deoxyuridine, and RX-3117 into DNA.
Topics: Cell Line, Tumor; Chromatography, Liquid; Cytidine; Deoxycytidine; DNA; DNA Methylation; Floxuridine; Gemcitabine; Humans; Limit of Detection; Mass Spectrometry; RNA | 2016 |
Extended exposure to substrate regulates the human equilibrative nucleoside transporter 1 (hENT1).
Topics: Antimetabolites, Antineoplastic; Binding Sites; Cytidine; Deoxycytidine; Equilibrative Nucleoside Transporter 1; Gemcitabine; HEK293 Cells; Humans; Protein Transport; Thioinosine | 2016 |
Identification of novel compounds against Tat-mediated human immunodeficiency virus-1 transcription by high-throughput functional screening assay.
Topics: 3-Deazauridine; Anti-HIV Agents; Cell Line; Cytidine; Deoxycytidine; Drug Repositioning; Gemcitabine; High-Throughput Screening Assays; HIV-1; Humans; Roscovitine; Small Molecule Libraries; tat Gene Products, Human Immunodeficiency Virus; Transcription, Genetic; Virus Replication | 2020 |
Zebularine suppressed gemcitabine-induced senescence and improved the cellular and plasma pharmacokinetics of gemcitabine, augmented by liposomal co-delivery.
Topics: Animals; Cell Line, Tumor; Cytidine; Deoxycytidine; Drug Resistance, Neoplasm; Gemcitabine; Liposomes; Pancreatic Neoplasms; Rats | 2021 |
In vitro assessment of a synergistic combination of gemcitabine and zebularine in pancreatic cancer cells.
Topics: Antimetabolites, Antineoplastic; Apoptosis Regulatory Proteins; Carcinoma, Pancreatic Ductal; Cell Line, Tumor; Cytidine; Cytidine Deaminase; Deoxycytidine; Gemcitabine; Humans; Pancreas; Pancreatic Neoplasms | 2021 |