Page last updated: 2024-08-17

cytidine and fluorouracil

cytidine has been researched along with fluorouracil in 35 studies

Research

Studies (35)

TimeframeStudies, this research(%)All Research%
pre-199016 (45.71)18.7374
1990's7 (20.00)18.2507
2000's7 (20.00)29.6817
2010's5 (14.29)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Lu, LJ; Randerath, K; Tseng, WC1
Osswald, H; Youssef, M1
De Clercq, E; Marquez, VE; Murase, J1
Allegra, CJ; Grem, JL1
Allegra, CJ; Chabner, BA; Chu, E; Grem, JL; Johnson, P; Yeh, GC1
Armstrong, RD; Cadman, EC; Lewis, M; Stern, SG1
Benedict, WF; Heidelberger, C; Peterson, AR1
Pitot, HC; Weiss, JW1
Beck, CF; Ingraham, JL; Neuhard, J; Thomassen, E1
Kaiser, II; Kwong, L1
Kaiser, II1
Kulikowski, TK; Schugar, D1
Dodd, DC; Hall, TC; Kessel, D1
Fischer, HU; Jobski, C; Mundinger, F; Ostertag, C; Vogt, P1
Hoshi, A; Kanzawa, F; Kuretani, K1
Stenram, U; Willén, R1
Hoshi, A; Iigo, M; Kuretani, K1
Beltz, RE; Hegarty, TJ; Waters, RN1
Abdulmalek, S; McCarthy, CM; Montoya, DP1
Chabner, BA; Longo, DL; Pinedo, HM1
Allegra, CJ; Chabner, BA; Chu, E; Grem, JL; Johnston, PG; Takimoto, CH1
McClarty, G; Tipples, G; Wang, LL; Wylie, JL1
BASCH, RS; KARNOFSKY, DA1
Cao, D; Kim, B; Leffert, JJ; McCabe, J; Pizzorno, G1
Magnier, M; Mulligan, RC; Stockwell, BR; Weissleder, R; Yen, L1
Al-Salabi, MI; Candlish, D; de Koning, HP; Gudin, S; Jarvis, SM; Quashie, NB; Ranford-Cartwright, LC1
Fukushima, M; Kazuno, H; Matsuda, A; Sasaki, T; Shimamoto, Y; Tsujimoto, H1
Echigo, S; Nishimura, K; Rikiishi, H; Shinohara, F; Suzuki, M1
Echigo, S; Endo, M; Rikiishi, H; Shinohara, F; Sugazaki, M; Suzuki, M1
Ebert, MO; Konrat, R; Kreutz, C; Micura, R; Puffer, B; Rieder, U1
Goltz, D; Jauch, C; Schott, H; Schott, TC; Schwendener, RA1
Li, JS; Luo, XR; Miao, L; Niu, Y1
Amblard, F; Cho, JH; Coats, SJ; Schinazi, RF1
Feigelstock, DA; Mihalik, KB1
Flis, K; Flis, S; Gnyszka, A1

Reviews

4 review(s) available for cytidine and fluorouracil

ArticleYear
Antimetabolites.
    Cancer chemotherapy and biological response modifiers, 1991, Volume: 12

    Topics: Animals; Antimetabolites; Antineoplastic Agents; Cytarabine; Cytidine; Drug Interactions; Drug Resistance; Floxuridine; Fluorouracil; Folic Acid Antagonists; Humans; Methotrexate; Neoplasms

1991
Oncogenic transformation of C3H/10T1/2 Cl 8 mouse embryo fibroblasts by inhibitors of nucleotide metabolism.
    Basic life sciences, 1985, Volume: 31

    Topics: Animals; Bromodeoxyuridine; Cell Line; Cell Transformation, Neoplastic; Cytidine; Deoxycytidine; Deoxyribonucleotides; DNA; Embryo, Mammalian; Fibroblasts; Floxuridine; Fluorouracil; Idoxuridine; Methotrexate; Mice; Mice, Inbred C3H; Mutation; Thymidine; Trifluridine

1985
Cancer chemotherapy and biological response modifiers annual 16. Introduction.
    Cancer chemotherapy and biological response modifiers, 1996, Volume: 16

    Topics: Animals; Antimetabolites, Antineoplastic; Cell Survival; Cytidine; DNA Damage; DNA Repair; Fluorouracil; Humans; Methotrexate; Purines

1996
Antimetabolites.
    Cancer chemotherapy and biological response modifiers, 1996, Volume: 16

    Topics: Animals; Antimetabolites, Antineoplastic; Cell Survival; Cytidine; DNA Damage; DNA Repair; Fluorouracil; Humans; Methotrexate; Purines

1996

Other Studies

31 other study(ies) available for cytidine and fluorouracil

ArticleYear
Effects of 5-fluorocytidine on mammalian transfer RNA and transfer RNA methyltransferases.
    Biochemical pharmacology, 1979, Volume: 28, Issue:4

    Topics: Animals; Cytidine; Escherichia coli; Fluorouracil; In Vitro Techniques; Mice; Mice, Inbred BALB C; Mycoplasma; RNA, Transfer; tRNA Methyltransferases

1979
Potentiation of the chemotherapeutic action of 5-fluorouracil by combination with cytidine or guanosine on HRS-sarcoma.
    Journal of cancer research and clinical oncology, 1979, Apr-12, Volume: 93, Issue:3

    Topics: Animals; Cytidine; Drug Synergism; Drug Therapy, Combination; Female; Fluorouracil; Guanosine; Lymphoma, Large B-Cell, Diffuse; Mice; Sarcoma, Experimental

1979
Broad-spectrum antiviral and cytocidal activity of cyclopentenylcytosine, a carbocyclic nucleoside targeted at CTP synthetase.
    Biochemical pharmacology, 1991, Jun-15, Volume: 41, Issue:12

    Topics: Adenosine; Amides; Antiviral Agents; Azauridine; Carbon-Nitrogen Ligases; Cell Division; Cytarabine; Cytidine; Deoxycytidine; Drug Synergism; Fluorouracil; HeLa Cells; Humans; Ligases; Nucleosides; Pyrazoles; Ribavirin; Ribonucleosides; Ribose; Thymidine; Tumor Cells, Cultured; Uracil; Virus Replication; Viruses

1991
Sequence-dependent interaction of 5-fluorouracil and arabinosyl-5-azacytosine or 1-beta-D-arabinofuranosylcytosine.
    Biochemical pharmacology, 1991, Jul-05, Volume: 42, Issue:2

    Topics: Antineoplastic Combined Chemotherapy Protocols; Azacitidine; Cell Division; Cell Line; Cell Nucleus; Cell Survival; Colonic Neoplasms; Cytarabine; Cytidine; Deoxycytosine Nucleotides; DNA, Neoplasm; Drug Administration Schedule; Drug Interactions; Fluorouracil; Humans; Nucleic Acids; Thymine Nucleotides; Tumor Stem Cell Assay

1991
Acute effect of 5-fluorouracil on cytoplasmic and nuclear dihydrofolate reductase messenger RNA metabolism.
    The Journal of biological chemistry, 1986, Jun-05, Volume: 261, Issue:16

    Topics: Animals; Cell Nucleus; Cells, Cultured; Cytidine; Cytoplasm; Dose-Response Relationship, Drug; Fluorouracil; Gene Expression Regulation; Leukemia, Experimental; Mice; RNA; RNA, Messenger; Tetrahydrofolate Dehydrogenase; Tritium

1986
Inhibition of ribosomal ribonucleic acid maturation by 5-azacytidine and 8-azaguanine in Novikoff hepatoma cells.
    Archives of biochemistry and biophysics, 1974, Volume: 160, Issue:1

    Topics: Animals; Azacitidine; Azaguanine; Carcinoma, Hepatocellular; Cells, Cultured; Cytidine; Dactinomycin; Electrophoresis, Polyacrylamide Gel; Fluorouracil; Guanosine; Isotope Labeling; Liver; Liver Neoplasms; Neoplasms, Experimental; Rats; RNA, Neoplasm; RNA, Ribosomal; Spectrophotometry, Ultraviolet; Time Factors; Tritium; Uridine

1974
Metabolism of pyrimidines and pyrimidine nucleosides by Salmonella typhimurium.
    Journal of bacteriology, 1972, Volume: 110, Issue:1

    Topics: Aminohydrolases; Cytidine; Cytosine; Deoxyuridine; Floxuridine; Flucytosine; Fluorouracil; Genetics, Microbial; Genotype; Mutation; Nucleosides; Nucleotidyltransferases; Pentosyltransferases; Phosphotransferases; Pyrimidines; Salmonella typhimurium; Thymidine; Uracil; Uracil Nucleotides; Uridine

1972
Identification of 5-fluorocytidine in RNA from Escherichia coli grown in the presence of 5-fluorouracil.
    FEBS letters, 1973, Jun-01, Volume: 32, Issue:2

    Topics: Carbon Radioisotopes; Chromatography, Gel; Chromatography, Paper; Chromatography, Thin Layer; Cytidine; Escherichia coli; Fluorine; Fluorouracil; Molecular Weight; Phosphoric Diester Hydrolases; RNA, Bacterial; RNA, Ribosomal; Spectrophotometry, Ultraviolet; Tritium; Venoms

1973
Thiobases in 5-fluorouracil-containing transfer RNA from Escherichia coli.
    Journal of molecular biology, 1972, Nov-14, Volume: 71, Issue:2

    Topics: Adenosine; Autoradiography; Chromatography, Thin Layer; Cytidine; Escherichia coli; Fluorouracil; Nucleosides; Nucleotides; RNA, Bacterial; RNA, Transfer; Spectrophotometry; Sulfur; Sulfur Isotopes; Tritium; Uridine

1972
Separation of anomeric pyrimidine nucleosides by thin-layer chromatography.
    Journal of chromatography, 1973, May-16, Volume: 79

    Topics: Chromatography, Thin Layer; Cytidine; Cytosine; Fluorouracil; Methods; Microchemistry; Nucleosides; Pyrimidines; Uridine

1973
Some determinants of drug responsiveness in bovine leukemia cells.
    Biochemical pharmacology, 1973, May-15, Volume: 22, Issue:10

    Topics: Animals; Antineoplastic Agents; Cattle; Cells, Cultured; Cytidine; Cytosine Nucleotides; Drug Resistance; Fluorouracil; Leukemia L1210; Leukemia, Experimental; Lymphoma, Non-Hodgkin; Mercaptopurine; Mice; Mice, Inbred Strains; Oxidative Phosphorylation; Pentosephosphates; Pentosyltransferases; Phosphotransferases

1973
[Clinical and experimental results of interstitial Brachy-Curie-therapy combined with radiation sensitizing agents in infiltrative growing brain neoplasms].
    Strahlentherapie, 1972, Volume: 143, Issue:3

    Topics: Animals; Brain Neoplasms; Bromodeoxyuridine; Carcinosarcoma; Cytidine; Fluorouracil; Guanosine; Iridium; Methotrexate; Neoplasms, Experimental; Radiation-Sensitizing Agents; Rats; Thymine

1972
Antitumor activity of cyclocytidine in a variety of tumors.
    Gan, 1972, Volume: 63, Issue:3

    Topics: Adenocarcinoma; Animals; Antineoplastic Agents; Carcinoma, Ehrlich Tumor; Cell Line; Cyclization; Cyclophosphamide; Cytarabine; Cytidine; Dose-Response Relationship, Drug; Female; Fluorouracil; Leukemia L1210; Leukemia, Experimental; Male; Mercaptopurine; Methotrexate; Mice; Mitomycins; Neoplasms, Experimental; Sarcoma 180

1972
The effect of 5-fluorouracil on ultrastructure and RNA labelling in the liver of rats following partial hepatectomy.
    Chemico-biological interactions, 1970, Volume: 2, Issue:2

    Topics: Animals; Autoradiography; Cell Nucleolus; Cytidine; Electrophoresis; Endoplasmic Reticulum; Fluorouracil; Hepatectomy; Liver; Liver Regeneration; Male; Microscopy, Electron; Rats; Ribosomes; RNA; Tritium

1970
Relationship between antitumor effect and metabolites of 5-fluorouracil in combination treatment with 5-fluorouracil and guanosine in ascites sarcoma 180 tumor system.
    Cancer research, 1983, Volume: 43, Issue:12 Pt 1

    Topics: Adenosine; Animals; Carbon Radioisotopes; Cytidine; Dose-Response Relationship, Drug; Female; Fluorouracil; Guanosine; Mice; Mice, Inbred Strains; Sarcoma 180; Structure-Activity Relationship; Uridine

1983
Enhancement and depression by inosine of the growth inhibitory action of 5-fluorouracil on cultured Jensen tumor cells.
    Biochemical and biophysical research communications, 1983, Apr-15, Volume: 112, Issue:1

    Topics: Animals; Cell Division; Cells, Cultured; Cytidine; Drug Synergism; Fluorouracil; Inosine; Neoplasms, Experimental; Rats

1983
Incorporation of 5-fluorouracil into RNA by Mycobacterium avium complex strain LM1.
    Canadian journal of microbiology, 1993, Volume: 39, Issue:6

    Topics: Biotransformation; Cytidine; Drug Resistance, Microbial; Fluorouracil; Mycobacterium avium Complex; RNA, Bacterial; Uracil; Uridine

1993
A single point mutation in CTP synthetase of Chlamydia trachomatis confers resistance to cyclopentenyl cytosine.
    The Journal of biological chemistry, 1996, Jun-28, Volume: 271, Issue:26

    Topics: Amino Acid Sequence; Antimetabolites, Antineoplastic; Carbon-Nitrogen Ligases; Chlamydia trachomatis; Cytidine; DNA, Bacterial; Drug Resistance, Microbial; Feedback; Fluorouracil; Ligases; Molecular Sequence Data; Point Mutation; Structure-Activity Relationship

1996
Effects of 5-fluorodeoxyuridine and related halogenated pyrimidines on the sand-dollar embryo.
    The Journal of biophysical and biochemical cytology, 1960, Volume: 7

    Topics: Cytidine; DNA; Female; Floxuridine; Fluorouracil; Humans; Orotic Acid; Pregnancy; Pyrimidines; Thymidine; Thymine; Uridine

1960
Abnormalities in uridine homeostatic regulation and pyrimidine nucleotide metabolism as a consequence of the deletion of the uridine phosphorylase gene.
    The Journal of biological chemistry, 2005, Jun-03, Volume: 280, Issue:22

    Topics: Adenosine; Animals; Antimetabolites, Antineoplastic; Blotting, Southern; Cytidine; Deoxyribonucleotides; DNA-Directed DNA Polymerase; Fluorouracil; Gene Deletion; Guanosine; Intestinal Mucosa; Kidney; Kinetics; Liver; Lung; Mice; Mice, Transgenic; Nucleotides; Pentobarbital; Pyrimidines; Reverse Transcriptase Polymerase Chain Reaction; Ribonucleotides; RNA, Messenger; Thymine Nucleotides; Time Factors; Tissue Distribution; Uridine; Uridine Phosphorylase

2005
Identification of inhibitors of ribozyme self-cleavage in mammalian cells via high-throughput screening of chemical libraries.
    RNA (New York, N.Y.), 2006, Volume: 12, Issue:5

    Topics: Acridine Orange; Adenosine; Animals; Antibiotics, Antineoplastic; beta-Galactosidase; Cell Line; Cytidine; Drug Evaluation, Preclinical; Enzyme Inhibitors; Ethidium; Fluorouracil; Gene Expression Regulation, Enzymologic; Guanine; Humans; Mice; Mice, Nude; Molecular Structure; RNA, Catalytic; Toyocamycin; Tubercidin; Uridine

2006
Trypanosoma brucei: a survey of pyrimidine transport activities.
    Experimental parasitology, 2006, Volume: 114, Issue:2

    Topics: Animals; Antimetabolites; Biological Transport; Cytidine; Cytosine; Female; Fluorouracil; Parasitic Sensitivity Tests; Pyrimidines; Rats; Rats, Wistar; Thymidine; Thymine; Trypanocidal Agents; Trypanosoma brucei brucei; Uridine

2006
Mechanism of action of a new antitumor ribonucleoside, 1-(3-C-ethynyl-beta-D-ribo-pentofuranosyl)cytosine (ECyd, TAS-106), differs from that of 5-fluorouracil.
    Oncology reports, 2007, Volume: 17, Issue:6

    Topics: Antineoplastic Agents; Cell Cycle; Cell Line, Tumor; Cell Proliferation; Cytidine; Fluorouracil; Humans; Inhibitory Concentration 50; Ribonucleosides; RNA Precursors; RNA, Ribosomal

2007
Epigenetic regulation of chemosensitivity to 5-fluorouracil and cisplatin by zebularine in oral squamous cell carcinoma.
    International journal of oncology, 2007, Volume: 31, Issue:6

    Topics: Antineoplastic Agents; Apoptosis; Carcinoma, Squamous Cell; Cell Cycle; Cell Line, Tumor; Cisplatin; Cytidine; DNA Methylation; Epigenesis, Genetic; Fluorouracil; Humans; Hydroxamic Acids; Mouth Neoplasms; Vorinostat

2007
Zebularine suppresses the apoptotic potential of 5-fluorouracil via cAMP/PKA/CREB pathway against human oral squamous cell carcinoma cells.
    Cancer chemotherapy and pharmacology, 2009, Volume: 64, Issue:2

    Topics: Adjuvants, Immunologic; Antimetabolites, Antineoplastic; Antineoplastic Agents; Apoptosis; Benzoquinones; Blotting, Western; Carcinoma, Squamous Cell; Cell Line, Tumor; Cisplatin; Cyclic AMP Response Element-Binding Protein; Cyclic AMP-Dependent Protein Kinases; Cytidine; DNA (Cytosine-5-)-Methyltransferases; Fluorouracil; Glycogen Synthase Kinase 3; Glycogen Synthase Kinase 3 beta; HSP90 Heat-Shock Proteins; Humans; In Situ Nick-End Labeling; Lactams, Macrocyclic; Lithium Chloride; Mouth Neoplasms; NF-kappa B; Phosphorylation; Proto-Oncogene Proteins c-bcl-2; Signal Transduction

2009
5-Fluoro pyrimidines: labels to probe DNA and RNA secondary structures by 1D 19F NMR spectroscopy.
    Nucleic acids research, 2009, Volume: 37, Issue:22

    Topics: Aptamers, Nucleotide; Cytidine; DNA; Flucytosine; Fluorouracil; Nuclear Magnetic Resonance, Biomolecular; Nucleic Acid Conformation; Nucleic Acid Probes; Oligonucleotides; Organophosphorus Compounds; RNA; Thermodynamics

2009
N⁴-[Alkyl-(hydroxyphosphono)phosphonate]-cytidine-new drugs covalently linking antimetabolites (5-FdU, araU or AZT) with bone-targeting bisphosphonates (alendronate or pamidronate).
    Bioorganic & medicinal chemistry, 2011, Jun-01, Volume: 19, Issue:11

    Topics: Alendronate; Animals; Antimetabolites, Antineoplastic; Arabinofuranosyluracil; Bone and Bones; Bone Density Conservation Agents; Cell Line, Tumor; Cytidine; Diphosphonates; Drug Screening Assays, Antitumor; Durapatite; Fluorouracil; Humans; Macrophages; Mice; Pamidronate; Uridine; Zidovudine

2011
Adenovirus-mediated double suicide gene selectively kills gastric cancer cells.
    Asian Pacific journal of cancer prevention : APJCP, 2012, Volume: 13, Issue:3

    Topics: Adenoviridae; Animals; Cell Cycle Checkpoints; Cell Line, Tumor; Cell Proliferation; Cell Survival; Cytidine; Cytosine Deaminase; Female; Fluorouracil; Ganciclovir; Gastric Mucosa; Genes, Transgenic, Suicide; Genetic Therapy; Genetic Vectors; Green Fluorescent Proteins; Humans; Inhibitor of Apoptosis Proteins; Mice; Mice, Inbred BALB C; Mice, Nude; Promoter Regions, Genetic; Recombinant Fusion Proteins; Repressor Proteins; Stomach Neoplasms; Survivin; Thymidine Kinase; Xenograft Model Antitumor Assays

2012
Synthesis of cyclopentanyl carbocyclic 5-fluorocytosine ((-)-5-fluorocarbodine) using a facially selective hydrogenation approach.
    The Journal of organic chemistry, 2013, Jan-18, Volume: 78, Issue:2

    Topics: Cyclization; Cyclopentanes; Cytidine; Flucytosine; Fluorouracil; Hydrogenation; Molecular Structure; Stereoisomerism

2013
Sensitivity of a ribavirin resistant mutant of hepatitis C virus to other antiviral drugs.
    PloS one, 2013, Volume: 8, Issue:9

    Topics: Amino Acid Substitution; Antiviral Agents; Cell Line; Cytidine; Drug Resistance, Viral; Fluorouracil; Hepacivirus; Hepatitis C, Chronic; Humans; Kinetics; Microbial Sensitivity Tests; Mutation; Ribavirin; Viral Proteins; Virus Replication

2013
DNA methyltransferase inhibitors improve the effect of chemotherapeutic agents in SW48 and HT-29 colorectal cancer cells.
    PloS one, 2014, Volume: 9, Issue:3

    Topics: Antineoplastic Combined Chemotherapy Protocols; Apoptosis; Azacitidine; Cell Cycle; Cell Line, Tumor; Colorectal Neoplasms; Cytidine; Decitabine; DNA Damage; DNA-Cytosine Methylases; Enzyme Inhibitors; Fluorouracil; Humans; Membrane Potential, Mitochondrial; Organoplatinum Compounds; Oxaliplatin

2014