cytidine has been researched along with deoxycytidine in 170 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 91 (53.53) | 18.7374 |
| 1990's | 19 (11.18) | 18.2507 |
| 2000's | 30 (17.65) | 29.6817 |
| 2010's | 21 (12.35) | 24.3611 |
| 2020's | 9 (5.29) | 2.80 |
| Authors | Studies |
|---|---|
| Bloomer, LC; Patil, VD; Townsend, LB; Wise, DS; Wotring, LL | 1 |
| Avery, TL; Chwang, TL; Fridland, A | 1 |
| Chawla, RR; Hampton, A; Kappler, F | 1 |
| Bao, H; Furman, PA; McBrayer, TR; Micolochick Steuer, HM; Murakami, E; Obikhod, A; Otto, MJ; Ramesh, M; Schinazi, RF; Stuyver, LJ; Whitaker, T | 1 |
| Bao, H; Furman, PA; Micolochick Steuer, HM; Murakami, E; Nachman, T; Niu, C; Otto, MJ; Sofia, MA; Wang, P; Whitaker, T | 1 |
| Hackstadt, T; Mallavia, LP | 1 |
| Karon, M; Lee, T; Monparler, RL | 1 |
| Goodman, J; Momparler, RL | 1 |
| Abbasi, MM; Beisler, JA; Voytek, P; Wolpert-DeFilippes, MK | 1 |
| Cihák, A; Veselý, J | 1 |
| Forsdyke, DR; Scott, FW | 1 |
| Shall, S | 1 |
| Jamieson, AT; Subak-Shape, JH | 1 |
| Bjursell, G; Eckstein, F; Hägerström, T; Hobbs, J; Skoog, L; Thelander, L | 1 |
| Bjursell, G; Skoog, L; Söderman, G; Thelander, L | 1 |
| Follmann, H; Hovemann, B | 1 |
| Rima, BK; Takahashi, I | 1 |
| Fujimura, S; Shimizu, M | 1 |
| Bulgakov, R; Cherny, B; Fridrikh, A; Khoíka, L; Sulimova, GE; Vaniushin, BF | 1 |
| Mak, TW; Wan, CW | 1 |
| Evans, HH; Evans, TE; Littman, SR | 1 |
| Mygind, B | 1 |
| Eichberg, J; Hauser, G | 1 |
| Leung, K; Roy-Burman, S; Visser, DW; von Dippe, PJ | 1 |
| Krajewska, E; Shugar, D | 1 |
| Brun, G; Goodgame, DM; Skapski, AC | 1 |
| Ratliff, RL; Walters, RA | 1 |
| Burchenal, JH; Chu, CK; Ciovacco, K; Dowling, MD; Fox, JJ; Kalaher, K; Kiefner, R; O'Toole, T; Watanabe, KA; Wempen, I | 1 |
| Garcia-Quintana, D; Garriga, P; Manyosa, J | 1 |
| Balzarini, J; De Clercq, E; Neyts, J; Snoeck, R | 1 |
| Call, KM; Thilly, WG | 1 |
| De Clercq, E; Marquez, VE; Murase, J | 1 |
| Mejer, J | 1 |
| August, EM; Marongiu, ME; Prusoff, WH | 1 |
| Chubb, S; Grindey, GB; Heinemann, V; Hertel, LW; Plunkett, W; Sen, A; Xu, YZ | 1 |
| Aran, JM; Plagemann, PG; Woffendin, C; Wohlhueter, RM | 1 |
| Ahluwalia, GS; Arnold, ST; Balzarini, J; Cohen, MB; Cooney, DA; Dalal, M; Johns, DG; Kang, GJ; McMahon, JB; Wilson, YA | 1 |
| Mejer, J; Mortensen, BT | 1 |
| Reichard, P; Spyrou, G | 2 |
| Chu, EH; Li, IC; Wu, CL | 1 |
| Guschlbauer, W; Hay, J; Jamieson, AT; Mengel, R; Wohlrab, F | 1 |
| Arnett, G; Coburn, WC; O'Dell, CA; Riordan, JM; Shannon, WM; Shealy, YF; Thorpe, MC | 1 |
| Benedict, WF; Heidelberger, C; Peterson, AR | 1 |
| Lin, TS; Prusoff, WH; Wang, ZH; Zhang, XH | 1 |
| Eichhorn, GL; Mays-Hoopes, LL; Singhal, RP | 1 |
| Nygaard, P | 1 |
| Dahbo, Y; Eriksson, S | 1 |
| de Groot, EJ; Schweiger, HG | 1 |
| Nicander, B; Reichard, P | 2 |
| Iujvidin, S; Mordoh, J | 1 |
| Chou, TC; Fanucchi, MP; Fox, JJ; Watanabe, KA | 1 |
| Ayers, O; Malinowski, N; Moyer, JD | 1 |
| Hosono, H; Kuno, S | 1 |
| Kamra, OP; Rajaraman, R | 1 |
| Wachsman, JT; Yau, S | 1 |
| Forsdyke, DR; Sjostrom, DA | 1 |
| Bertinchamps, AJ; Mathur-De Vré, R | 1 |
| Cory, JG; George, CB; Mansell, MM; Wilkinson, DS | 1 |
| Singer, B; Sun, L | 1 |
| Bloch, A; McPartland, RP; Wang, MC; Weinfeld, H | 1 |
| Brox, LW; Hendler, SS; LePage, GA; Shannahoff, DH | 1 |
| Hofert, JF | 1 |
| Leung, KK; Visser, DW | 1 |
| Taketo, A; Taketo, Y | 1 |
| Baranovskaia, LI; Ibraimov, AI; Zakharov, AF | 1 |
| Berger, AE; Kuentzel, SL; Neil, GL | 1 |
| Anderson, WR; Daves, GD; Lis, AW; McLaughlin, DL; McLaughlin, RK | 1 |
| Vig, BK | 1 |
| Cooper, GM; Greer, S | 1 |
| Degenhardt, KH; Fränz, J; Kleinbrecht, J | 1 |
| DiFate, V; Shapiro, R; Welcher, M | 1 |
| Dingman, CW; Peacock, AC; Salomon, R; Zeiger, RS | 1 |
| Baranovskaya, LI; Zakharov, AF | 1 |
| Haar, W; Maurer, W; Rüterjans, H | 1 |
| Jones, PA; Taylor, SM | 1 |
| Niwa, O; Sugahara, T | 1 |
| Kidder, GW | 1 |
| Böhmer, FD; Graetz, H; Grosse, R; Langen, P; Lehmann, W | 1 |
| Bacon, PE; Chiba, P; Cory, JG | 1 |
| Evans, WE; Sinkule, JA | 1 |
| Cory, JG; Montgomery, JA; Sato, A | 1 |
| Cysyk, RL; Hoerauf, RM; Karle, JM | 1 |
| Goz, B; Orr, C; Wharton, W | 1 |
| Chen, TS | 1 |
| Akerblom, L; Pontis, E; Reichard, P | 1 |
| Hoshi, A; Kuretani, K; Saneyoshi, M; Yoshida, M | 1 |
| Katz, DJ; Townsend, LB; Wise, DS | 1 |
| Kizaki, H; Lui, MS; Weber, G | 1 |
| Deveski, WB; Dudman, NP; Tattersall, MH | 1 |
| Bairamjan, TL; Zakharov, AF | 1 |
| Eckstein, F; Eliasson, R; Pontis, E; Reichard, P | 1 |
| Kulinska, K; Laaksonen, A | 1 |
| Bianchi, V; Borella, S; Calderazzo, F; Chieco Bianchi, L; Ferraro, P; Reichard, P | 1 |
| Andersen, PS; Hammer, K; Martinussen, J | 1 |
| Sasvári-Székely, M; Spasokukotskaja, T; Staub, M | 1 |
| Cory, AH; Cory, JG; Hertel, LW; Kroin, JS | 1 |
| Bhattacharyya, SN; Chabita, K; Mandal, PC; Mukherjee, T; Rath, MC; Saha, A | 1 |
| Asseline, U; Auffray, P; Dupret, D; Nguyen, HK; Thuong, NT | 1 |
| Matsuda, A; Ogawa, A; Sasaki, T; Tanaka, M | 1 |
| Gilski, M; Jaskólski, M | 1 |
| Erbs, P; Exinger, F; Jund, R; Kurtz, JE | 1 |
| Enger, MD; Gurley, LR; Ratliff, RL; Tobey, RA; Walters, RA | 1 |
| Casado, FJ; Inzillo, SM; Larrayoz, IM; Lostao, MP; Mata, JF; Pastor-Anglada, M | 1 |
| Kodama, T; Matsuda, A; Nomura, M; Shuto, S | 1 |
| Evans, VJ; Price, FM; Rotherham, J | 2 |
| Bontemps, F; Cardoen, S; Delacauw, A; Ferrant, A; Rosier, JF; Smal, C; Van den Berghe, G; Van Den Neste, E | 1 |
| Ashihara, H; Katahira, R | 1 |
| Li, NS; Piccirilli, JA | 2 |
| Aravindakumar, CT; Rao, BS; Schuchmann, MN; von Sonntag, C; von Sonntag, J | 1 |
| EIDINOFF, ML; PEREZ, AG; RICH, MA | 1 |
| ABRAMS, R; EDMONDS, M; LIBENSON, L | 1 |
| BROWN, GB; SCOTTO, GT; THOMSON, RY | 1 |
| MILLS, GC | 1 |
| REICHARD, P; RUTBERG, L | 1 |
| HURLBERT, RB; MOORE, EC | 1 |
| Florea-Wang, D; Haapala, E; Hakala, K; Hovinen, J; Mattinen, J; Vilpo, J | 1 |
| Cheng, YC; Dutschman, GE; Hsu, CH; Liou, JY | 1 |
| Leen, R; Van Gennip, AH; Van Kuilenburg, AB; Verschuur, AC | 1 |
| Backman, J; Ellingsen, DG; Greibrokk, T; Kronberg, L; Lundanes, E; Molander, P; Olsen, R; Sjöholm, R; Thomassen, Y; Thorud, S; Øvrebø, S | 1 |
| Fujioka, A; Fukushima, M; Kazuno, H; Matsuda, A; Sakamoto, K; Sasaki, T | 1 |
| Cherry, JC; Farrar, WL; Fox, SD; Hodge, DR; Hurt, EM; Kelley, JA; Munroe, DJ; Peng, B | 1 |
| Bierau, J; Caron, HN; Leen, R; Meinsma, R; van Gennip, AH; van Kuilenburg, AB | 1 |
| Chuang, JC; Jones, PA; Kwan, JM; Li, TW; Liang, G; Yang, AS; Yoo, CB | 1 |
| Fujimoto, S; Hotta, A; Koma, M; Nagai, K; Nagasawa, K | 1 |
| Breadmore, MC; Hilder, EF; Potter, OG | 1 |
| Ali, S; Cammack, N; Jiang, WR; Kang, H; Le Pogam, S; McCown, MF; Najera, I; Rajyaguru, S; Symons, J | 1 |
| Leen, R; Medema, J; Rodermond, H; van Bree, C; van Kuilenburg, A | 1 |
| Bassit, L; Bennett, M; Grier, J; Schinazi, RF | 1 |
| Baubec, T; Mittelsten Scheid, O; Pecinka, A; Rozhon, W | 1 |
| Ali, S; Alker, A; Cammack, N; Inocencio, N; Jiang, WR; Kang, H; Klumpp, K; Le Pogam, S; Leveque, V; Ma, H; Najera, I; Philipp, F; Smith, M; Symons, J | 1 |
| Barten-Van Rijbroek, AD; Kal, HB; Leen, R; Rodermond, HM; Van Bree, C; Van Kuilenburg, AB | 1 |
| Wadkins, RM; Zhang, X | 1 |
| Fattahi, A; Pourjavadi, A; Tehrani, ZA | 1 |
| Iams, TA; McKee, EE; Morris, GW; Slepchenko, KG | 1 |
| Saada, A | 1 |
| Bao, J; Bender, DM; Dantzig, AH; Diseroad, WD; Law, KL; Magnus, NA; McCarthy, JR; Perkins, EJ; Peterson, JA; Pu, YJ; Remick, DM; Reutzel-Edens, SM; Starling, JJ; Stephenson, GA; Vaid, RK; Zhang, D | 1 |
| Betham, B; Bhagwat, AS; Marquez, VE; Shalhout, S | 1 |
| Barrientos, EY; Torres, AL; Wrobel, K | 1 |
| Agback, T; Belfrage, AK; Benckestock, K; Boothee, M; de Kock, H; Johansson, NG; Jonckers, TH; Kalayanov, G; Klumpp, K; Lachau-Durand, S; Lin, TI; Lindqvist, A; Martin, JA; Nilsson, M; Pelcman, M; Pinho, P; Raboisson, P; Rosenquist, S; Rydegård, C; Samuelsson, B; Simmen, K; Smith, DB; Sund, C; Terelius, Y; Vandyck, K; Vrang, L; Wähling, H; Wikström, K; Winqvist, A; Zhou, XX | 1 |
| Barclay, L; Costantini, VP; Lee, D; McBrayer, TR; Schinazi, RF; Vinjé, J; Whitaker, T | 1 |
| Pockros, PJ | 1 |
| Chouliaras, L; Coleman, PD; Delvaux, E; Grover, A; Hof, PR; Kenis, G; Mastroeni, D; Rutten, BP; Steinbusch, HW; van den Hove, DL | 1 |
| Arai, D; Hayakawa, K; Hirosawa, M; Murakami, N; Shiota, K; Tabei, Y; Tanaka, S; Yagi, S | 1 |
| Okamura, H; Sasaki, S; Taniguchi, Y | 1 |
| Chang, J; Li, Z; Shi, J; Wang, R; Wang, X; Xie, Y; Yang, L | 1 |
| Chang, J; Chen, X; Cheng, T; Dong, L; Guo, M; Guo, X; Jiang, J; Peng, Y; Wang, Q; Zhang, J; Zhang, Y | 1 |
| Antinori, A; Bonora, S; Castagna, A; d'Arminio Monforte, A; De Luca, A; Maserati, R; Perno, CF | 1 |
| Ahn, CH; Fine, T; Kashi, R; Kaye, J; Kim, DJ; Lee, YB; Ohne, O; Peters, GJ; Smid, K; Yang, MY | 1 |
| Terui, Y | 1 |
| Berden, G; Frieler, CE; Oomens, J; Rodgers, MT; Wu, RR; Yang, B | 1 |
| Berridge, G; Goldin, R; Kessler, BM; Kriaucionis, S; Pugh, KM; Thézénas, ML; Zauri, M | 1 |
| Honeywell, RJ; Kathmann, I; Kristensen, MH; Peters, GJ; Sarkisjan, D | 1 |
| Coe, IR; Naydenova, Z; Zafar, M | 1 |
| Chen, J; Tang, Y; Wang, X; Zhong, D; Zhou, Z | 1 |
| Aggarwal, AK; Buku, A; Choudhury, JR; Prakash, L; Prakash, S; Rechkoblit, O | 1 |
| Cao, X; Chen, Q; Guo, C; Guo, M; Wang, Y; Xie, C; Zheng, S | 1 |
| Balboni, B; Benaim, E; El Hassouni, B; Giovannetti, E; Heaton, C; Honeywell, RJ; Kim, DJ; Lee, YB; Peters, GJ; Peterson, C; Poore, J; Sarkisjan, D | 1 |
| Choi, BS; Choi, MS; Kim, DE; Kim, HG; Kim, K; Park, CM; Shin, Y; Yoon, CH | 1 |
| Leung, E; Lozano Hernandez, L; Reginald-Opara, JN; Svirskis, D; Tang, M; Wang, H; Wu, Z | 1 |
| Bhutkar, S; Dukhande, V; Patel, K; Patki, M; Saraswat, A | 1 |
| Herzig, JW; Husain, M; Khan, I; Mirza, A; Qazi, RE; Salim, A | 1 |
| Chudinov, AV; Guseinov, TO; Kuznetsova, VE; Lapa, SA; Levashova, AI; Miftakhov, RA; Novikov, RA; Shershov, VE; Solyev, PN; Zasedatelev, AS | 1 |
| Gasparavičiūtė, R; Jauniškis, V; Lapinskaitė, R; Meškienė, R; Meškys, R; Skrodenytė, E; Sūdžius, J; Tamulaitienė, G; Tauraitė, D; Tiškus, M; Urbelienė, N; Urbelis, G; Vaitekūnas, J | 1 |
| Hu, M; Tao, Y; Teng, F; Wang, L | 1 |
| Frańska, M; Hoffmann, M; Jankowski, W; Półrul, P | 1 |
| Friedecký, D; Koberna, K; Ligasová, A; Piskláková, B | 1 |
4 review(s) available for cytidine and deoxycytidine
| Article | Year |
|---|---|
Oncogenic transformation of C3H/10T1/2 Cl 8 mouse embryo fibroblasts by inhibitors of nucleotide metabolism.
Topics: Animals; Bromodeoxyuridine; Cell Line; Cell Transformation, Neoplastic; Cytidine; Deoxycytidine; Deoxyribonucleotides; DNA; Embryo, Mammalian; Fibroblasts; Floxuridine; Fluorouracil; Idoxuridine; Methotrexate; Mice; Mice, Inbred C3H; Mutation; Thymidine; Trifluridine | 1985 |
Molecular recognition motifs in cytidinium and 2'-deoxycytidinium salts with composite anions.
Topics: Anions; Cations; Crystallography; Cytidine; Deoxycytidine; Deoxycytosine Nucleotides; Hydrogen Bonding; Models, Molecular | 1998 |
Nucleoside/nucleotide analogue polymerase inhibitors in development.
Topics: Cytidine; Deoxycytidine; Drugs, Investigational; Enzyme Inhibitors; Hepacivirus; Hepatitis C; Humans; Protein Conformation; RNA-Dependent RNA Polymerase; Sofosbuvir; Uridine Monophosphate; Viral Nonstructural Proteins | 2013 |
RX-3117 (fluorocyclopentenyl cytosine): a novel specific antimetabolite for selective cancer treatment.
Topics: Administration, Oral; Antimetabolites, Antineoplastic; Biological Availability; Cytidine; Deoxycytidine; Gemcitabine; Humans; Neoplasms; Patient Selection | 2019 |
166 other study(ies) available for cytidine and deoxycytidine
| Article | Year |
|---|---|
Synthesis and biological activity of a novel adenosine analogue, 3-beta-D-ribofuranosylthieno[2,3-d]pyrimidin-4-one.
Topics: Adenosine; Adenosine Kinase; Animals; Antineoplastic Agents; Biotransformation; In Vitro Techniques; Leukemia L1210; Mice; Pyrimidine Nucleosides | 1985 |
2'-O-nitro-1-beta-D-arabinofuranosylcytosine. A new derivative of 1-beta-D-arabinofuranosylcytosine that resists enzymatic deamination and has antileukemic activity.
Topics: Animals; Antimetabolites, Antineoplastic; Cytarabine; Drug Evaluation, Preclinical; Female; Leukemia L1210; Mice; Mice, Inbred Strains | 1983 |
Species- or isozyme-specific enzyme inhibitors. 5. Differential effects of thymidine substituents on affinity for rat thymidine kinase isozymes.
Topics: Animals; Cytoplasm; In Vitro Techniques; Isoenzymes; Kinetics; Mitochondria; Pyrimidine Nucleosides; Rats; Thymidine; Thymidine Kinase; Tissue Distribution | 1982 |
Mechanism of activation of beta-D-2'-deoxy-2'-fluoro-2'-c-methylcytidine and inhibition of hepatitis C virus NS5B RNA polymerase.
Topics: Antiviral Agents; Catalysis; Deoxycytidine; Hepacivirus; Hepatitis C; Humans; Mutation; Phosphorylation; RNA-Dependent RNA Polymerase; RNA, Viral; Structure-Activity Relationship; Viral Nonstructural Proteins; Virus Replication | 2007 |
The mechanism of action of beta-D-2'-deoxy-2'-fluoro-2'-C-methylcytidine involves a second metabolic pathway leading to beta-D-2'-deoxy-2'-fluoro-2'-C-methyluridine 5'-triphosphate, a potent inhibitor of the hepatitis C virus RNA-dependent RNA polymerase.
Topics: Antiviral Agents; Cell Line; Cytidine; Deoxycytidine; Hepacivirus; Humans; Microbial Sensitivity Tests; Phosphorylation; Replicon; RNA-Dependent RNA Polymerase; Structure-Activity Relationship; Uridine Triphosphate | 2008 |
Deoxypyrimidine nucleoside metabolism in varicella-zoster virus-infected cells.
Topics: Cell Line; Cytidine; Deoxycytidine; Deoxyribonucleosides; Deoxyuridine; Enzyme Induction; Herpesvirus 3, Human; Humans; Hydrogen-Ion Concentration; Molecular Weight; Thymidine; Thymidine Kinase | 1978 |
Cellular phosphorylation of 1-beta-D-arabinofuranosylcytosine 5-azacytidine with intact fibrosarcoma and leukemic cells.
Topics: Animals; Azacitidine; Binding, Competitive; Cells, Cultured; Cricetinae; Cytarabine; Cytidine; Deoxycytidine; Drug Resistance; Fibrosarcoma; Kinetics; Leukemia, Experimental; Mice; Phosphorus; Sarcoma, Experimental | 1975 |
In vitro cytotoxic and biochemical effects of 5-aza-2'-deoxycytidine.
Topics: Azacitidine; Cell Division; Cell Survival; Cells, Cultured; Cytidine; Deoxycytidine; DNA, Neoplasm; Fibrosarcoma; Neoplasm Proteins; Neoplasms, Experimental; RNA, Neoplasm | 1977 |
Comparative studies of the cytostatic action and metabolism of 5-azacytidine and 5,6-dihydro-5-azacytidine.
Topics: Animals; Azacitidine; Cell Division; Cells, Cultured; Cytidine; Cytidine Deaminase; Deoxycytidine; Drug Synergism; Kinetics; Leukemia L1210; Oxidative Phosphorylation; Tetrahydrouridine; Thymidine; Uridine | 1977 |
Depression of DNA synthesis in mouse spleen after treatment with 5-aza-2'-deoxycytidine.
Topics: Animals; Azacitidine; Cytidine; Deoxycytidine; DNA; Female; Male; Mice; Nucleoside-Phosphate Kinase; Spleen; Thymidine; Thymidine Monophosphate | 1979 |
Isotope-dilution studies of the effects of 5-fluorodeoxyuridine and hydroxyurea on the incorporation of deoxycytidine and thymidine by cultured thymus cells.
Topics: Animals; Cells, Cultured; Cytidine; Deoxyadenosines; Deoxycytidine; Deoxyribonucleosides; DNA Replication; Floxuridine; Hydroxyurea; Methotrexate; Rats; Thymidine; Thymus Gland | 1976 |
Proceedings: Experimental manipulation of the specific activity of poly(ADP-ribose) polymerase.
Topics: Animals; Cell Division; Cell Line; Cell Nucleus; Cytidine; Deoxycytidine; Fibroblasts; Kinetics; Male; Mice; N-Glycosyl Hydrolases; NAD+ Nucleosidase; Spermatogenesis; Testis; Time Factors; Trout; Uridine | 1975 |
Herpes simplex virus specified deoxypyrimidine kinase and the uptake of exogenous nucleosides by infected cells.
Topics: Cell Line; Cytidine; Deoxycytidine; DNA; Enzyme Induction; Mutation; Phosphotransferases; RNA; Simplexvirus; Thymidine; Thymidine Kinase | 1976 |
2'-Deoxy-2'-azidocytidine, a new inhibitor of DNA replication in mammalian cells.
Topics: Cell Line; Cytidine; Deoxycytidine; Depression, Chemical; DNA Polymerase I; DNA Polymerase II; DNA Replication; DNA, Viral; Kinetics; Molecular Weight; Polyomavirus | 1977 |
2'-Deoxy-2'-azidocytidine inhibits the initiation of polyoma DNA synthesis.
Topics: Azides; Cell Line; Chromosome Mapping; Cytidine; Deoxycytidine; DNA Replication; DNA Restriction Enzymes; DNA, Viral; Electrophoresis, Agar Gel; Microscopy, Electron; Molecular Weight; Polyomavirus; Virus Replication | 1977 |
The determination of low ribonucleotide reductase activity in plant extracts.
Topics: Adenosine; Chlorophyta; Chromatography, Ion Exchange; Cytidine; Cytosine Nucleotides; Deoxyadenosines; Deoxycytidine; Plant Extracts; Ribonucleotide Reductases | 1977 |
Metabolism of pyrimidine bases and nucleosides in Bacillus subtilis.
Topics: Bacillus subtilis; Cytidine; Cytidine Deaminase; Cytosine; Deoxycytidine; Deoxyuridine; DNA, Bacterial; Mutation; Nucleoside Deaminases; Pentosyltransferases; Phosphotransferases; Pyrimidine Nucleosides; Pyrimidines; Uracil; Uridine | 1977 |
Studies on the abnormal excretion of pyrimidine nucleosides in the urine of Yoshida ascites sarcoma-bearing rats. Increased excretion of deoxycytidine, pseudouridine and cytidine.
Topics: Animals; Cytidine; Deoxycytidine; Liver; Male; Neoplasm Transplantation; Orotic Acid; Pseudouridine; Pyrimidine Nucleosides; Rats; Sarcoma, Yoshida; Uridine | 1978 |
[On the impossibility of the incorporation of 5-methylcytosine and its nucleosides into higher plant DNA].
Topics: Cytidine; Cytosine; Deoxycytidine; DNA; Plants; Thymine Nucleotides; Triticum | 1978 |
Deoxycytidine kinase and cytosine nucleoside deaminase activities in synchronized cultures of normal rat kidney cells.
Topics: Cell Cycle; Cell Survival; Cells, Cultured; Cytarabine; Cytidine; Cytosine; Deoxycytidine; Nucleoside Deaminases; Phosphotransferases; Substrate Specificity | 1978 |
Effect of ionizing radiation on nucleoside metabolism in Physarum polycephalum.
Topics: Cell Cycle; Cytidine; Cytidine Triphosphate; Deoxycytidine; DNA; Gamma Rays; Nucleosides; Physarum; Thymidine | 1978 |
Transport of pyrimidine nucleosides in cells of Escherichia coli K 12.
Topics: Biological Transport, Active; Culture Media; Cytidine; Deoxycytidine; Dinitrophenols; Escherichia coli; Ethylmaleimide; Genotype; Kinetics; Mercuribenzoates; Methylnitronitrosoguanidine; Mutation; Pyrimidine Nucleosides; Radiation Effects; Species Specificity; Ultraviolet Rays; Uridine | 1975 |
Accumulation and metabolism of phosphatidyl-CMP1 (CDP-diglyceride) in the pineal gland of the rat.
Topics: Animals; Cytidine; Cytidine Diphosphate Diglycerides; Deoxycytidine; Inositol; Kinetics; Nucleoside Diphosphate Sugars; Pineal Gland; Propranolol; Rats | 1976 |
Deoxycytidine transport in the presence of a cytidine deaminase inhibitor and the transport of uracil in Escherichia coli B.
Topics: Adenine Phosphoribosyltransferase; Anti-Bacterial Agents; Arsenates; Biological Transport; Cyanides; Cytidine; Cytidine Deaminase; Deoxyadenosines; Deoxycytidine; Escherichia coli; Guanosine; Kinetics; Nucleoside Deaminases; Pentosyltransferases; Tetrahydrouridine; Time Factors; Uracil; Uridine | 1975 |
Alkylated cytosine nucleosides: substrate and inhibitor properties in enzymatic deamination.
Topics: Alkylation; Chemical Phenomena; Chemistry; Chromatography; Chromatography, Paper; Cytarabine; Cytidine; Cytidine Deaminase; Deoxycytidine; Kinetics; Nucleoside Deaminases; Pyrimidines; Salmonella typhimurium | 1975 |
Reaction of ribonucleosides and deoxynucleosides with copper(II) acetate.
Topics: Acetates; Chemical Phenomena; Chemistry; Copper; Cytidine; Deoxycytidine; Deoxyribonucleosides; Deoxyuridine; Ribonucleosides; Spectrum Analysis; Thymidine; Uridine | 1975 |
Lack of specific correlation of the deoxycytidine triphosphate pool level with rate of DNA synthesis.
Topics: Cell Line; Cytidine; Cytosine Nucleotides; Deoxycytidine; Deoxyribonucleotides; Deoxyuridine; DNA Replication; Thymidine | 1975 |
Antileukemic effects of pseudoisocytidine, a new synthetic pyrimidine C-nucleoside.
Topics: Animals; Cell Line; Cells, Cultured; Cytidine; Deoxycytidine; Drug Evaluation, Preclinical; Isomerism; Leukemia, Experimental; Mice; Mice, Inbred C57BL; Mice, Inbred DBA; Neoplasms, Experimental; Thymidine | 1976 |
Study of polynucleotide conformation by resolution-enhanced ultraviolet spectroscopy poly(rC) and poly(dC).
Topics: Cytidine; Cytosine; Deoxycytidine; Hydrogen-Ion Concentration; Nucleic Acid Conformation; Poly C; Polynucleotides; Spectrophotometry, Ultraviolet | 1992 |
Particular characteristics of the anti-human cytomegalovirus activity of (S)-1-(3-hydroxy-2-phosphonylmethoxypropyl)cytosine (HPMPC) in vitro.
Topics: Animals; Antiviral Agents; Cidofovir; Cytarabine; Cytidine; Cytomegalovirus; Cytosine; Deoxycytidine; DNA, Viral; Ganciclovir; Humans; Organophosphonates; Organophosphorus Compounds; Tumor Cells, Cultured; Virus Replication | 1991 |
5-Azacytidine inhibits the induction of transient TK-deficient cells by 5-bromodeoxyuridine. A novel hypothesis for the facilitation of hypermethylation by 5-bromodeoxyuridine.
Topics: Azacitidine; Bromodeoxyuridine; Cell Cycle; Chromatography, High Pressure Liquid; Cytidine; Deoxycytidine; DNA; Dose-Response Relationship, Drug; Drug Antagonism; Gene Expression Regulation; Humans; In Vitro Techniques; Methylation; Mutation; Thymidine Kinase | 1991 |
Broad-spectrum antiviral and cytocidal activity of cyclopentenylcytosine, a carbocyclic nucleoside targeted at CTP synthetase.
Topics: Adenosine; Amides; Antiviral Agents; Azauridine; Carbon-Nitrogen Ligases; Cell Division; Cytarabine; Cytidine; Deoxycytidine; Drug Synergism; Fluorouracil; HeLa Cells; Humans; Ligases; Nucleosides; Pyrazoles; Ribavirin; Ribonucleosides; Ribose; Thymidine; Tumor Cells, Cultured; Uracil; Virus Replication; Viruses | 1991 |
The impact of selected nucleosides on the cytotoxicity of Ara-C in HL60 cells.
Topics: Cell Line; Cell Survival; Cytarabine; Cytidine; Deoxyadenosines; Deoxycytidine; Deoxyguanosine; Drug Interactions; Humans; Kinetics; Leukemia, Promyelocytic, Acute; Nucleosides; Tetrahydrouridine; Uridine | 1991 |
Effect of 3'-deoxythymidin-2'-ene (d4T) on nucleoside metabolism in H9 cells.
Topics: Amino Acids; Cell Division; Cell Survival; Cells, Cultured; Cytidine; Deoxycytidine; Dideoxynucleosides; Humans; Nucleosides; Stavudine; Thymidine; Thymidine Kinase; Uridine | 1990 |
Inhibition of ribonucleotide reduction in CCRF-CEM cells by 2',2'-difluorodeoxycytidine.
Topics: Cell Line; Cytidine; Deoxycytidine; Deoxycytosine Nucleotides; DNA; Gemcitabine; Humans; Hydroxyurea; Oxidation-Reduction; Ribonucleoside Diphosphate Reductase; Ribonucleotides; Thymine Nucleotides | 1990 |
Mobility of nucleoside transporter of human erythrocytes differs greatly when loaded with different nucleosides.
Topics: 2-Chloroadenosine; Cytidine; Deoxyadenosines; Deoxycytidine; Erythrocytes; Humans; Kinetics; Nucleosides; Substrate Specificity | 1990 |
Arabinosyl-5-azacytosine: mechanisms of native and acquired resistance.
Topics: Animals; Azacitidine; Biological Transport; Colonic Neoplasms; Cytidine; Deoxycytidine; Deoxycytidine Kinase; DNA; Drug Resistance; Humans; Leukemia P388; Mice; Phosphorylation | 1986 |
Reduction of ara-C cytotoxicity in HL 60 cells by addition of deoxycytidine, cytidine or increased level of cytidine deaminase.
Topics: Bone Marrow; Bone Marrow Cells; Cell Division; Cytarabine; Cytidine; Cytidine Deaminase; Deoxycytidine; Deoxycytidine Kinase; Humans; Leukemia, Promyelocytic, Acute; Nucleoside Deaminases; Phosphotransferases; Tetrahydrouridine; Tretinoin; Tumor Cells, Cultured | 1989 |
Intracellular compartmentation of deoxycytidine nucleotide pools in S phase mouse 3T3 fibroblasts.
Topics: Animals; Cells, Cultured; Cytidine; Cytidine Triphosphate; Cytosine Nucleotides; Deoxycytidine; Deoxycytosine Nucleotides; Fibroblasts; Interphase; Kinetics; Mice | 1989 |
Single-step selection of mammalian cell mutants deficient in CTP synthetase.
Topics: Animals; Carbon-Nitrogen Ligases; Cell Line; Cell Separation; Cricetinae; Cytidine; Deoxycytidine; DNA; Ligases; Mutation; Thymidine; Uridine | 1989 |
The effect of 2'-fluoro-2'-deoxycytidine on herpes virus growth.
Topics: Animals; Cell Division; Cricetinae; Cytarabine; Cytidine; Deoxycytidine; Herpesvirus 1, Equid; Herpesvirus 1, Suid; Humans; Phosphorylation; Simplexvirus; Thymidine Kinase | 1985 |
Carbocyclic analogues of 5-halocytosine nucleosides.
Topics: Bromodeoxycytidine; Chemical Phenomena; Chemistry; Cytarabine; Cytidine; Deoxycytidine; Halogens; Simplexvirus; Virus Replication | 1986 |
Synthesis and antiviral evaluation of carbocyclic analogues of 2'-azido- and 2'-amino-2'-deoxycytidine.
Topics: Antiviral Agents; Cytidine; Deoxycytidine | 1988 |
DNA methylation in aging of mice.
Topics: Aging; Animals; Base Composition; Chromatography, High Pressure Liquid; Cytidine; Deoxycytidine; DNA; Female; Liver; Male; Methylation; Mice; Mice, Inbred C57BL | 1987 |
On the role of cytidine deaminase in cellular metabolism.
Topics: Cytidine; Cytidine Deaminase; Deoxycytidine; Enterobacteriaceae; Escherichia coli; Hematopoietic Stem Cells; Humans; Lymphocytes; Nucleoside Deaminases; Pyrimidines; Salmonella; Uridine Phosphorylase | 1986 |
Compartmentation of dCTP pools. Evidence from deoxyliponucleotide synthesis.
Topics: Animals; Cell Compartmentation; Cell Line; Cytidine; Deoxycytidine; Deoxycytosine Nucleotides; DNA Replication; Fibroblasts; Mice; Mice, Inbred BALB C | 1987 |
On the mechanism of deoxyribonucleoside toxicity in human T-lymphoblastoid cells. Reversal of growth inhibition by addition of cytidine.
Topics: Cell Division; Cell Line; Cytidine; Deoxyadenosines; Deoxycytidine; Deoxyguanosine; Deoxyribonucleosides; Deoxyribonucleotides; Humans; Leukemia, Lymphoid; Phosphorylation; T-Lymphocytes; Thymidine | 1985 |
Enzymic ribonucleoside reduction at the non-phosphorylated level in Acetabularia.
Topics: Acetabularia; Adenosine Triphosphate; Catalysis; Cell Nucleus; Chlorophyta; Cytidine; Deoxycytidine; Ribonucleotide Reductases | 1985 |
On the regulation of deoxyribonucleotide synthesis.
Topics: Animals; Aphidicolin; Cell Cycle; Cells, Cultured; Cytidine; Deoxycytidine; Deoxyribonucleotides; Diterpenes; DNA Replication; Fibroblasts; Homeostasis; Hydroxyurea; Kinetics; Mice; Thymidine | 1985 |
Metabolism of phosphatidyl-dCMP in sarcoma 180 cells. Effect of chlorpromazine, phosphatidic acid and inositol.
Topics: Animals; Chlorpromazine; Chromatography, Paper; Cytidine; Deoxycytidine; Deoxycytidine Monophosphate; Deoxycytosine Nucleotides; In Vitro Techniques; Inositol; Mice; Microsomes; Phosphatidic Acids; Sarcoma 180 | 1986 |
Kinetics and substrate specificity of human and canine cytidine deaminase.
Topics: Animals; Arabinofuranosyluracil; Cytarabine; Cytidine; Cytidine Deaminase; Deoxycytidine; Dogs; Humans; Kinetics; Liver; Nucleoside Deaminases; Substrate Specificity | 1986 |
Salvage of circulating pyrimidine nucleosides by tissues of the mouse.
Topics: Animals; Cytidine; Deoxycytidine; Deoxyuridine; Half-Life; Male; Metabolic Clearance Rate; Mice; Pyrimidine Nucleosides; Thymidine; Tissue Distribution; Uracil; Uridine | 1985 |
The purification and properties of cytidine deaminase from Escherichia coli.
Topics: Aminohydrolases; Chromatography; Cytarabine; Cytidine; Deamination; Deoxycytidine; Deoxyribonucleosides; Edetic Acid; Electrophoresis; Escherichia coli; Hydrogen-Ion Concentration; Metals; Molecular Weight; Pyrimidine Nucleosides; Ribonucleosides; Sulfhydryl Reagents; Urea | 1973 |
Modification of radiation-induced genetic damage in Drosophila melanogaster male germ cells with nucleic acid precursors. 3. Effects on the premeiotic cells.
Topics: Animals; Bromodeoxyuridine; Chromosome Aberrations; Cytidine; Deoxycytidine; Deoxyribonucleosides; DNA; Drosophila melanogaster; Female; Genes, Lethal; Genes, Recessive; Male; Meiosis; Radiation Genetics; Radiation-Sensitizing Agents; Sex Chromosomes; Spermatozoa | 1974 |
The Bacillus megaterium ribonucleotide reductase: evidence for a B 12 coenzyme requirement.
Topics: Adenosine Triphosphate; Bacillus megaterium; Carbon Radioisotopes; Cobamides; Cytidine; Cytosine Nucleotides; Deoxycytidine; Hydroxyurea; Magnesium; Ribonucleotide Reductases; Tritium | 1973 |
Isotope-dilution analysis of rate-limiting steps and pools affecting the incorporation of thymidine and deoxycytidine into cultured thymus cells.
Topics: Animals; Biological Transport; Carbon Radioisotopes; Cells, Cultured; Culture Media; Cytidine; Deoxycytidine; Deoxyribonucleosides; Floxuridine; Isotope Labeling; Kinetics; Methotrexate; Rats; Thymidine; Thymidylate Synthase; Thymus Gland; Time Factors; Tritium | 1974 |
An NMR study of the relative interaction abilities of different pyrimidine nucleosides with serotonin.
Topics: Bromodeoxyuridine; Cytidine; Deoxycytidine; Floxuridine; Idoxuridine; Magnetic Resonance Spectroscopy; Pyrimidine Nucleosides; Serotonin; Thymidine; Uridine | 1974 |
Inhibition of nucleic acid synthesis in Ehrlich tumor cells by periodate-oxidized adenosine and adenylic acid.
Topics: Adenosine; Adenosine Monophosphate; Animals; Borohydrides; Carbon Radioisotopes; Carcinoma, Ehrlich Tumor; Cells, Cultured; Chromatography, Ion Exchange; Chromatography, Paper; Cytidine; Deoxycytidine; DNA, Neoplasm; Electrophoresis, Polyacrylamide Gel; Mice; Oxidation-Reduction; Periodic Acid; Ribonucleotide Reductases; Ribosomes; RNA, Neoplasm; RNA, Ribosomal; Time Factors; Tritium; Uridine | 1974 |
Reaction of cytidine with ethylating agents.
Topics: Alkylating Agents; Carbon Radioisotopes; Carbonates; Chemical Phenomena; Chemistry; Chromatography, Paper; Cytidine; Cytosine Nucleotides; Deoxycytidine; Electrophoresis, Paper; Guanine Nucleotides; Hydrocarbons, Iodinated; Hydrogen-Ion Concentration; Mesylates; Polynucleotides; Potassium; Pyrimidine Nucleosides; Spectrophotometry, Ultraviolet; Sulfuric Acids | 1974 |
Cytidine 5'-triphosphate synthetase as a target for inhibition by the antitumor agent 3-deazauridine.
Topics: Animals; Cells, Cultured; Cytidine; Cytosine Nucleotides; Deoxycytidine; Deoxyuridine; Enzyme Inhibitors; Leukemia L1210; Ligases; Liver; Mice; Thymidine; Uracil Nucleotides; Uridine | 1974 |
Studies on the growth inhibition and metabolism of 2'-deoxy-2'-fluorocytidine in cultured human lymphoblasts.
Topics: Carbon Radioisotopes; Cell Division; Cell Line; Cells, Cultured; Cytidine; Deoxycytidine; Deoxyribonucleosides; DNA, Neoplasm; Fluorine; Humans; Leukemia, Lymphoid; Tritium | 1974 |
An acute effect of high oxygen tension on the uptake of 3H-deoxycytidine into thymocyte deoxyribonucleic acid.
Topics: Animals; Cells, Cultured; Cytidine; Deoxycytidine; DNA; Oxygen; Rats; T-Lymphocytes; Thymidine; Time Factors; Tritium; Uridine | 1974 |
A new deoxycytidine analog, 5-hydroxy-2'-deoxycytidine.
Topics: Aminohydrolases; Biological Transport; Carbon Radioisotopes; Cell Division; Cell Line; Chromatography, Ion Exchange; Cytidine; Deoxycytidine; Deoxyribonucleosides; Escherichia coli; Hydroxylation; Kinetics; Lymphocytes; Spectrophotometry, Ultraviolet; Structure-Activity Relationship; Time Factors | 1974 |
Nucleoside catabolism in Streptococcus hemolyticus.
Topics: Biodegradation, Environmental; Cell-Free System; Chromatography, Gel; Cytidine; Deoxycytidine; Escherichia coli; Guanosine; Hemolysin Proteins; Nucleosides; Phosphotransferases; Streptococcus; Thymidine; Uridine | 1974 |
[Differential condensation of human chromosomes in mitosis under the influence of 5-bromdesoxycytidine].
Topics: Chromosomes; Cytidine; Cytological Techniques; Deoxycytidine; Female; Humans; Lymphocytes; Male; Mitosis; Time Factors | 1974 |
A microbiological assay for cyclocytidine--disposition studies in mice.
Topics: Animals; Biological Assay; Cytarabine; Cytidine; Deoxycytidine; Enterococcus faecalis; Female; Mice; Nucleosides; Uridine | 1973 |
5-Chlorocytosine. Occurrence in salmon sperm deoxyribonucleic acid.
Topics: Animals; Chlorine; Cytidine; Deoxycytidine; DNA; Male; Methods; Protein Hydrolysates; Salmon; Spermatozoa | 1973 |
Synergism between deoxyribose cytidine and adriamycin in causing chromosome aberrations in human leukocytes.
Topics: Chromatin; Chromosome Aberrations; Chromosomes; Cytidine; Deoxycytidine; Deoxyribonucleosides; Doxorubicin; Drug Synergism; Humans; In Vitro Techniques; Leukocytes; Mitosis | 1973 |
The effect of inhibition of cytidine deaminase by tetrahydrouridine on the utilization of deoxycytidine and 5-bromodeoxycytidine for deoxyribonucleic acid synthesis.
Topics: Adenocarcinoma; Aminohydrolases; Animals; Bone Marrow; Bromine; Cytidine; Deoxycytidine; Deoxyribonucleosides; Deoxyuridine; DNA; DNA, Neoplasm; Female; Fluorine; Intestine, Small; Lymphoma; Male; Mammary Neoplasms, Experimental; Mice; Mice, Inbred BALB C; Mice, Inbred C3H; Neoplasms, Experimental; Spleen; Testis; Tritium; Uridine | 1973 |
Supernumerary distal limb elements induced by 5-fluoro-2'-deoxycytidine in mice.
Topics: Abnormalities, Drug-Induced; Animals; Cytidine; Deoxycytidine; Deoxyribonucleosides; Limb Deformities, Congenital; Mice | 1974 |
Deamination of cytosine derivatives by bisulfite. Mechanism of the reaction.
Topics: Chemical Phenomena; Chemistry; Cytidine; Cytosine; Deamination; Deoxycytidine; Evaluation Studies as Topic; Hydrogen-Ion Concentration; Hydrolysis; Kinetics; Mathematics; Methods; Models, Chemical; Sodium; Sulfites | 1974 |
Role of base composition in the electrophoresis of heat-treated deoxyribonucleic acid from HeLa and mouse cells in composite polyacrylamide gels.
Topics: Adenosine; Animals; Carbon Radioisotopes; Cell Nucleus; Chromatography, Paper; Cytidine; Cytosine Nucleotides; Deoxycytidine; DNA; DNA, Neoplasm; Electrophoresis, Polyacrylamide Gel; Guanine Nucleotides; Guanosine; HeLa Cells; Hot Temperature; Mice; Mice, Inbred C57BL; Nucleic Acid Denaturation; Nucleosides; Nucleotides; Polysaccharides; Thymidine; Tritium | 1974 |
H3-deoxycytidine incorporation into X-chromosomes differentially condensed under 5-bromodeoxyuridine treatment in cases of 49,XXXXY, 48,XXXX, 47,XXX, 46,X,i(Xq), and 45,X-46,X,i(Xq).
Topics: Autoradiography; Bromodeoxyuridine; Chromosome Mapping; Cytidine; Deoxycytidine; Deoxyribonucleosides; DNA Replication; Female; Humans; Karyotyping; Lymphocytes; Mitosis; Sex Chromosome Aberrations; Sex Chromosomes; Tritium | 1974 |
Proton-magnetic-resonance studies of complexes of pancreatic ribonuclease A with pyrimidine and purine nucleotides.
Topics: Adenosine Monophosphate; Animals; Crystallography; Cytidine; Cytosine Nucleotides; Deoxycytidine; Deuterium; Hydrogen-Ion Concentration; Magnetic Resonance Spectroscopy; Pancreas; Protons; Purine Nucleotides; Pyrimidine Nucleotides; Ribonucleases; Uracil Nucleotides | 1974 |
Cellular differentiation, cytidine analogs and DNA methylation.
Topics: Adipose Tissue; Animals; Azacitidine; Cell Differentiation; Cells, Cultured; Cytarabine; Cytidine; Decitabine; Deoxycytidine; DNA; DNA (Cytosine-5-)-Methyltransferases; Methylation; Methyltransferases; Mice; Muscles; Structure-Activity Relationship | 1980 |
5-Azacytidine induction of mouse endogenous type C virus and suppression of DNA methylation.
Topics: Animals; Azacitidine; Bromodeoxyuridine; Cell Line; Cytidine; Deoxycytidine; DNA Replication; DNA, Viral; Dose-Response Relationship, Drug; Kinetics; Mice; Mice, Inbred BALB C; Retroviridae; Virus Replication | 1981 |
Characteristics of cytidine aminohydrolase activity in Trypanosoma cruzi and Crithidia fasciculata.
Topics: Anaerobiosis; Animals; Crithidia; Cytidine; Cytidine Deaminase; Deoxycytidine; Hydrogen-Ion Concentration; Kinetics; Molecular Weight; Nucleoside Deaminases; Pyrimidine Nucleosides; Substrate Specificity; Trypanosoma cruzi | 1984 |
Is ribonucleotide reductase in Ehrlich ascites mammary tumour cells the target of a growth inhibitor purified from bovine mammary gland?
Topics: Animals; Carcinoma, Ehrlich Tumor; Cattle; Cells, Cultured; Cytidine; Deoxycytidine; Deoxyuridine; Electrophoresis, Polyacrylamide Gel; Epidermal Growth Factor; Female; Growth Inhibitors; Hydroxyurea; Insulin; Mammary Glands, Animal; Mice; Nucleosides; Ribonucleotide Reductases; Uracil; Uridine | 1984 |
Studies directed toward testing the "channeling" hypothesis--ribonucleotides----DNA in leukemia L1210 cells.
Topics: Animals; Aphidicolin; Cytidine; Deoxycytidine; Diterpenes; DNA Replication; Hydroxyurea; Leukemia L1210; Mice; Multienzyme Complexes; Nucleic Acid Synthesis Inhibitors; Ribonucleotide Reductases; Ribonucleotides; Thymidylate Synthase | 1984 |
Dynamics of pyrimidine deoxynucleoside triphosphate pools in relationship to DNA synthesis in 3T6 mouse fibroblasts.
Topics: Animals; Cytidine; Deoxycytidine; DNA Replication; Fibroblasts; Mice; Pyrimidine Nucleosides; Thymidine; Thymine Nucleotides | 1983 |
High-performance liquid chromatographic assay for cytosine arabinoside, uracil arabinoside and some related nucleosides.
Topics: Arabinofuranosyluracil; Child; Chromatography, High Pressure Liquid; Cytarabine; Cytidine; Deoxycytidine; Humans; Infusions, Parenteral; Kinetics; Leukemia, Myeloid, Acute; Uridine | 1983 |
Synergistic inhibition of leukemia L1210 cell growth in vitro by combinations of 2-fluoroadenine nucleosides and hydroxyurea or 2,3-dihydro-1H-pyrazole[2,3-a]imidazole.
Topics: Animals; Cell Survival; Cytidine; Deferoxamine; Deoxyadenosines; Deoxycytidine; Drug Synergism; Hydroxyurea; Kinetics; Leukemia L1210; Mice; Pyrazoles; Vidarabine | 1984 |
Labelling of the thymidine and deoxycytidine bases of DNA by [2-14C]deoxycytidine in cultured L1210 cells.
Topics: 3-Deazauridine; Animals; Carbon Radioisotopes; Cytarabine; Cytidine; Deoxycytidine; DNA; Leukemia L1210; Mice; Tetrahydrouridine; Thymidine | 1983 |
Inhibition by deoxycytidine, cytidine, and beta-cytosine arabinoside of the induction of alkaline phosphatase activity in HeLa cells.
Topics: Alkaline Phosphatase; Cytarabine; Cytidine; Deoxycytidine; DNA; Enzyme Induction; HeLa Cells; Hot Temperature; Humans; Idoxuridine; Kinetics | 1980 |
Effects of arabinosyl cytosine and 5-azacytidine on the intestinal absorption of nutrients.
Topics: Amino Acids; Animals; Cytarabine; Cytidine; Deoxycytidine; Electrolytes; Glucose; Intestinal Absorption; Male; Mice; Mice, Inbred Strains | 1982 |
Effects of azidocytidine on DNA synthesis and deoxynucleotide pools of mouse fibroblast cell lines.
Topics: Animals; Cells, Cultured; Cytidine; Deoxycytidine; Deoxyribonucleotides; DNA Replication; Fibroblasts; Kinetics; Mice | 1982 |
Mode of action of 5-fluorocytidine and 5-fluoro-2'-deoxycytidine in L5178Y cells in vitro.
Topics: Animals; Antineoplastic Agents; Cells, Cultured; Cytidine; Deoxycytidine; Leukemia L5178; Mice | 1982 |
Synthesis of pyridazine analogues of the naturally occurring nucleosides cytidine, uridine, deoxycytidine, and deoxyuridine.
Topics: Animals; Antineoplastic Agents; Chemical Phenomena; Chemistry; Cytidine; Deoxycytidine; Deoxyuridine; Hydrolysis; In Vitro Techniques; Leukemia L1210; Magnetic Resonance Spectroscopy; Mice; Pyridazines; Pyrimidine Nucleosides; Uridine | 1982 |
Biochemical pharmacology of acivicin in rat hepatoma cells.
Topics: Animals; Carbon-Nitrogen Ligases; Cell Line; Cell Survival; Cytidine; Deoxycytidine; Deoxyribonucleotides; Dose-Response Relationship, Drug; Drug Synergism; Glycine; Guanosine; Isoxazoles; Ligases; Liver; Liver Neoplasms, Experimental; Oxazoles; Rats; Ribonucleotides | 1982 |
Radioimmunoassays of plasma thymidine, uridine, deoxyuridine, and cytidine/deoxycytidine.
Topics: Animals; Cytidine; Deoxycytidine; Deoxyuridine; Immune Sera; Radioimmunoassay; Thymidine; Uridine | 1981 |
5-Bromodeoxycytidine in the study of sister chromatid exchanges in human lymphocytes.
Topics: Bromodeoxycytidine; Chromatids; Crossing Over, Genetic; Cytidine; Deoxycytidine; DNA; Humans; Lymphocytes; Sister Chromatid Exchange; Thymidine | 1980 |
Interactions of 2'-modified azido- and haloanalogs of deoxycytidine 5'-triphosphate with the anaerobic ribonucleotide reductase of Escherichia coli.
Topics: Anaerobiosis; Cytidine; Cytosine; Deoxycytidine; Escherichia coli; Free Radicals; Ribonucleotide Reductases; Structure-Activity Relationship | 1994 |
Hydration of cytidine, 2'-deoxycytidine and their phosphate salts in the aqueous solutions. A molecular dynamics computer simulation study.
Topics: Computer Simulation; Cytidine; Deoxycytidine; Hydrogen Bonding; Models, Molecular; Molecular Structure; Phosphates; Thermodynamics; Water | 1994 |
Inhibition of ribonucleotide reductase by 2'-substituted deoxycytidine analogs: possible application in AIDS treatment.
Topics: Acquired Immunodeficiency Syndrome; Antiviral Agents; Cells, Cultured; Cytidine; Deoxycytidine; Gemcitabine; Humans; Hydroxyurea; In Vitro Techniques; Prodrugs; Ribonucleotide Reductases; Zidovudine | 1994 |
Nucleotide metabolism in Lactococcus lactis: salvage pathways of exogenous pyrimidines.
Topics: Cytidine; Deoxycytidine; Deoxyuridine; Enzymes; Escherichia coli; Kinetics; Lactococcus lactis; Pyrimidines; Species Specificity; Uracil; Uridine | 1994 |
Deoxyribocytidine is salvaged not only into DNA but also into phospholipid precursors. IV. Exogenous deoxyribocytidine can be used with the same efficacy as (ribo)cytidine for lipid activation.
Topics: Cells, Cultured; Cytidine; Deoxycytidine; DNA; Humans; Kinetics; Lymphocytes; Models, Biological; Palatine Tonsil; Phospholipids; Thymidine; Tritium | 1993 |
Effects of 2',2'-difluorodeoxycytidine (Gemcitabine) on wild type and variant mouse leukemia L1210 cells.
Topics: Animals; Antimetabolites, Antineoplastic; Carbon Radioisotopes; Cytidine; Deoxycytidine; Gemcitabine; Leukemia L1210; Mice; Ribonucleotide Reductases; Tumor Cells, Cultured | 1993 |
Reactions of OH and eaq- adducts of cytosine and its nucleosides or nucleotides with Cu(II) ions in dilute aqueous solutions: a steady-state and pulse radiolysis study.
Topics: Copper; Cytidine; Cytosine; Deoxycytidine; Hydroxyl Radical; Pulse Radiolysis; Solutions | 1996 |
Modification of DNA duplexes to smooth their thermal stability independently of their base content for DNA sequencing by hybridization.
Topics: Base Composition; Cytidine; Deoxycytidine; DNA; Guanosine; Heating; Molecular Structure; Nucleic Acid Hybridization; Oligodeoxyribonucleotides; Sequence Analysis, DNA | 1997 |
Nucleosides and nucleotides. 180. Synthesis and antitumor activity of nucleosides that have a hydroxylamino group instead of a hydroxyl group at the 2'- or 3'-position of the sugar moiety.
Topics: Animals; Antimetabolites, Antineoplastic; Cytidine; Deoxycytidine; DNA, Neoplasm; Drug Screening Assays, Antitumor; Female; Fibrosarcoma; Humans; Inhibitory Concentration 50; Leukemia P388; Neoplasm Transplantation; RNA, Neoplasm; Structure-Activity Relationship; Tumor Cells, Cultured | 1998 |
New insights into the pyrimidine salvage pathway of Saccharomyces cerevisiae: requirement of six genes for cytidine metabolism.
Topics: Amino Acid Sequence; Chromatography; Cytidine; Cytidine Deaminase; Deoxycytidine; Drug Resistance; Models, Biological; Molecular Sequence Data; Phenotype; Phosphorylation; Point Mutation; Pyrimidines; Saccharomyces cerevisiae; Sequence Analysis, DNA; Substrate Specificity; Uridine; Uridine Kinase | 1999 |
Effects of X-irradiation on DNA precursor metabolism and deoxyribonucleoside triphosphate pools in Chinese hamster cells.
Topics: Animals; CHO Cells; Cricetinae; Cytidine; Deoxyadenine Nucleotides; Deoxycytidine; Deoxycytosine Nucleotides; Deoxyguanine Nucleotides; Deoxyribonucleotides; DNA Damage; DNA Repair; DNA Replication; Dose-Response Relationship, Radiation; Intracellular Fluid; RNA; S Phase; Thymidine; Thymine Nucleotides | 1974 |
Electrogenic uptake of nucleosides and nucleoside-derived drugs by the human nucleoside transporter 1 (hCNT1) expressed in Xenopus laevis oocytes.
Topics: Animals; Antimetabolites, Antineoplastic; Antineoplastic Agents; Antiviral Agents; Carrier Proteins; Cytidine; Deoxycytidine; Electric Conductivity; Gemcitabine; Gene Expression; Humans; Membrane Potentials; Membrane Proteins; Nucleoside Transport Proteins; Nucleosides; Oocytes; Sodium; Substrate Specificity; Uridine; Vidarabine; Xenopus laevis | 2000 |
An efficient method for the preparation of 1'alpha-branched-chain sugar pyrimidine ribonucleosides from uridine: the first conversion of a natural nucleoside into 1'-substituted ribonucleosides.
Topics: Cyclization; Cytarabine; Cytidine; Deoxycytidine; Glycosylation; Molecular Structure; Organoselenium Compounds; Pyrimidine Nucleosides; Ribonucleosides; Selenium; Silicon; Stereoisomerism; Structure-Activity Relationship; Uridine; Vinyl Compounds | 2001 |
Some aspects of the role of vitamin B12 in nucleic acid synthesis in a neoplastic C3H mouse cell strain. I. Growth studies.
Topics: Adenine; Adenosine; Animals; Cell Division; Cytidine; Deoxyadenosines; Deoxycytidine; Deoxyuridine; DNA, Neoplasm; Folic Acid; Guanine; Mice; Nucleic Acid Precursors; Nucleosides; Pyrimidines; Thymidine; Tumor Cells, Cultured; Uridine; Vitamin B 12 | 1970 |
Some aspects of the role of vitamin B12 in nucleic acid synthesis in a neoplastic C3H mouse cell strain. II. Incorporation of precursors.
Topics: Adenine; Animals; Carbon Radioisotopes; Cytidine; Deoxycytidine; Deoxyuridine; DNA, Neoplasm; Mice; Nucleic Acid Precursors; Nucleosides; Thymidine; Tumor Cells, Cultured; Uridine; Vitamin B 12 | 1970 |
Resistance to 2-chloro-2'-deoxyadenosine of the human B-cell leukemia cell line EHEB.
Topics: Antineoplastic Agents; Cell Cycle; Cell Survival; Cladribine; Cytidine; Deoxycytidine; Deoxycytidine Kinase; DNA, Neoplasm; Dose-Response Relationship, Drug; Drug Resistance, Neoplasm; Humans; Inhibitory Concentration 50; Leukemia, B-Cell; Nucleotides; Phosphorylation; Ribonucleotide Reductases; Thymidine Kinase; Tumor Cells, Cultured | 2001 |
Profiles of pyrimidine biosynthesis, salvage and degradation in disks of potato (Solanum tuberosum L.) tubers.
Topics: Carbon Radioisotopes; Culture Techniques; Cytidine; Cytidine Deaminase; Cytosine; Cytosine Deaminase; Deoxycytidine; Deoxycytidine Kinase; Deoxyribonucleosides; Enzymes; Multienzyme Complexes; Nucleoside Deaminases; Orotate Phosphoribosyltransferase; Orotidine-5'-Phosphate Decarboxylase; Pentosyltransferases; Phosphotransferases; Plant Stems; Pyrimidine Nucleosides; Pyrimidine Phosphorylases; Pyrimidines; Pyrimidinones; Solanum tuberosum; Thymidine; Thymidine Kinase; Uracil; Uridine; Uridine Kinase; Uridine Monophosphate; Uridine Phosphorylase | 2002 |
Synthesis of the phosphoramidite derivative of 2'-deoxy-2'-C-beta-methylcytidine.
Topics: Cytidine; Deoxycytidine; Indicators and Reagents; Magnetic Resonance Spectroscopy; Models, Molecular; Uridine | 2003 |
The reactions of cytidine and 2'-deoxycytidine with SO4.- revisited. Pulse radiolysis and product studies.
Topics: Buffers; Cations; Cytidine; Deoxycytidine; Free Radicals; Kinetics; Oxygen; Phosphates; Poly C; Poly U; Pulse Radiolysis; Pyrimidines; Sulfates | 2003 |
Growth inhibition of a human tumor cell strain by 5-fluorocytidine and 5-fluoro-2'-deoxycytidine: reversal studies.
Topics: Animals; Cytidine; Deoxycytidine; Humans; Neoplasms; Neoplasms, Experimental; Nucleosides; Nucleotides | 1959 |
Conversion of cytidine 5'-phosphate to deoxycytidine 5'-phosphate in cell-free mammalian extracts.
Topics: Animals; Cytidine; Deoxycytidine; Diploidy; Mammals; Nucleosides; Nucleotides; Phosphates | 1960 |
On the conversion of cytidine to deoxycytidine in the rat.
Topics: Animals; Cytidine; Deoxycytidine; Nucleosides; Rats | 1962 |
Cytidine and deoxycytidine nucleotides or erythrocytes.
Topics: Cytidine; Deoxycytidine; Erythrocytes; Nucleosides; Nucleotides | 1960 |
Formation of deoxycytidine 5'-phosphate from cytidine 5'-phosphate with enzymes from Escherichia coli.
Topics: Biochemical Phenomena; Cytidine; Deoxycytidine; Escherichia coli; Nucleosides; Nucleotides; Phosphates | 1960 |
Reduction of cytidine nucleotides to deoxycytidine nucleotides by mammalian enzymes.
Topics: Animals; Biochemical Phenomena; Cytidine; Deoxycytidine; Enzymes; Mammals; Nucleosides; Nucleotides | 1962 |
Reactions of N,N-bis(2-chloroethyl)-p-aminophenylbutyric acid (chlorambucil) with 2'-deoxycytidine, 2'-deoxy-5-methylcytidine, and thymidine.
Topics: Antineoplastic Agents, Alkylating; Chlorambucil; Chromatography, High Pressure Liquid; Cytidine; Deoxycytidine; DNA Adducts; Magnetic Resonance Spectroscopy; Spectrometry, Mass, Electrospray Ionization; Thymidine | 2004 |
Synthesis of the phosphoramidite derivatives of 2'-deoxy-2'-C-alpha-methylcytidine and 2'-deoxy-2'-C-alpha-hydroxymethylcytidine: analogues for chemical dissection of RNA's 2'-hydroxyl group.
Topics: Cytidine; Deoxycytidine; Hydroxyl Radical; Indicators and Reagents; Magnetic Resonance Spectroscopy; Models, Molecular; RNA; Uridine | 2004 |
Phosphorylation of Cytidine, Deoxycytidine, and Their Analog Monophosphates by Human UMP/CMP Kinase Is Differentially Regulated by ATP and Magnesium.
Topics: Adenosine Triphosphate; Cytidine; Cytidine Monophosphate; Deoxycytidine; Deoxycytidine Monophosphate; Humans; Kinetics; Nucleoside-Phosphate Kinase; Phosphorylation; Substrate Specificity | 2005 |
Increased cytotoxicity of 2',2'-difluoro-2'-deoxycytidine in human leukemic cell-lines after a preincubation with cyclopentenyl cytosine.
Topics: Antimetabolites, Antineoplastic; Antineoplastic Agents; Apoptosis; Carbon-Nitrogen Ligases; Cell Line, Tumor; Cell Separation; Clinical Trials as Topic; Cytidine; Deoxycytidine; DNA; Dose-Response Relationship, Drug; Flow Cytometry; Gemcitabine; HL-60 Cells; Humans; Necrosis; Neoplasms; Time Factors | 2004 |
Reaction of glyoxal with 2'-deoxyguanosine, 2'-deoxyadenosine, 2'-deoxycytidine, cytidine, thymidine, and calf thymus DNA: identification of DNA adducts.
Topics: Cytidine; Deoxyadenosines; Deoxycytidine; Deoxyguanosine; DNA; DNA Adducts; Glyoxal; Magnetic Resonance Spectroscopy; Thymidine | 2005 |
Possible antitumor activity of 1-(3-C-ethynyl-beta-D-ribo-pentofuranosyl)cytosine (ECyd, TAS-106) against an established gemcitabine (dFdCyd)-resistant human pancreatic cancer cell line.
Topics: Animals; Antineoplastic Agents; Cell Line, Tumor; Cytidine; Deoxycytidine; Deoxyribonucleotides; Drug Resistance, Neoplasm; Gemcitabine; Humans; Inhibitory Concentration 50; Male; Mice; Mice, Nude; Pancreatic Neoplasms; Ribonucleotides; RNA, Messenger; Xenograft Model Antitumor Assays | 2005 |
Interleukin 6 supports the maintenance of p53 tumor suppressor gene promoter methylation.
Topics: Apoptosis; Azacitidine; Base Sequence; Cell Cycle; Cell Line, Tumor; Cytidine; Decitabine; Deoxycytidine; DNA (Cytosine-5-)-Methyltransferase 1; DNA (Cytosine-5-)-Methyltransferases; DNA Methylation; Gene Silencing; Genes, p53; Humans; Interleukin-6; Molecular Sequence Data; Multiple Myeloma; Promoter Regions, Genetic; Sulfites; Tumor Suppressor Protein p53 | 2005 |
Cyclopentenyl cytosine-induced activation of deoxycytidine kinase increases gemcitabine anabolism and cytotoxicity in neuroblastoma.
Topics: Antineoplastic Agents; Cell Differentiation; Cell Line, Tumor; Cell Survival; Cytidine; Deoxycytidine; Deoxycytidine Kinase; Dose-Response Relationship, Drug; Drug Synergism; Enzyme Activation; Gemcitabine; Humans; Immunoblotting; N-Myc Proto-Oncogene Protein; Neuroblastoma; Nuclear Proteins; Oncogene Proteins | 2006 |
Comparison of biological effects of non-nucleoside DNA methylation inhibitors versus 5-aza-2'-deoxycytidine.
Topics: Antimetabolites, Antineoplastic; Azacitidine; Carcinoma, Transitional Cell; Catechin; Cell Line, Tumor; Colorectal Neoplasms; Cytidine; Decitabine; Deoxycytidine; DNA Methylation; DNA Modification Methylases; Enzyme Inhibitors; Female; Gene Silencing; HT29 Cells; Humans; Hydralazine; Male; Procainamide; Prostatic Neoplasms; Reverse Transcriptase Polymerase Chain Reaction | 2005 |
Cytidine is a novel substrate for wild-type concentrative nucleoside transporter 2.
Topics: Amino Acid Substitution; Animals; Antimetabolites, Antineoplastic; Biological Transport; Chlorocebus aethiops; COS Cells; Cytarabine; Cytidine; Deoxycytidine; Dose-Response Relationship, Drug; Gemcitabine; Genotype; Kinetics; Male; Membrane Transport Proteins; Mice; Thymidine; Transfection; Tritium; Uridine | 2006 |
Boronate functionalised polymer monoliths for microscale affinity chromatography.
Topics: Boronic Acids; Chromatography, Affinity; Cytidine; Deoxycytidine; Methylmethacrylates; Ribonucleosides | 2006 |
The hepatitis C virus replicon presents a higher barrier to resistance to nucleoside analogs than to nonnucleoside polymerase or protease inhibitors.
Topics: Antiviral Agents; Cytidine; Deoxycytidine; Drug Resistance, Viral; Hepacivirus; Nucleosides; Oligopeptides; Protease Inhibitors; Replicon; Serine Endopeptidases; Viral Nonstructural Proteins; Virus Replication | 2008 |
Cyclopentenyl cytosine increases gemcitabine radiosensitisation in human pancreatic cancer cells.
Topics: Apoptosis; Cell Line, Tumor; Cell Survival; Cytidine; Cytidine Triphosphate; Deoxycytidine; Dose-Response Relationship, Drug; Drug Resistance, Neoplasm; Drug Screening Assays, Antitumor; Drug Synergism; Gemcitabine; Humans; Lung Neoplasms; Pancreatic Neoplasms; Radiation Tolerance; Radiation-Sensitizing Agents | 2008 |
Combinations of 2'-C-methylcytidine analogues with interferon-alpha2b and triple combination with ribavirin in the hepatitis C virus replicon system.
Topics: Antiviral Agents; Cells, Cultured; Computer Simulation; Cytidine; Deoxycytidine; Drug Synergism; Drug Therapy, Combination; Hepacivirus; Humans; Interferon alpha-2; Interferon-alpha; Models, Chemical; Monte Carlo Method; Polymerase Chain Reaction; Recombinant Proteins; Replicon; Ribavirin; RNA, Ribosomal; RNA, Viral | 2008 |
Effective, homogeneous and transient interference with cytosine methylation in plant genomic DNA by zebularine.
Topics: Arabidopsis; Cytidine; Cytosine; Deoxycytidine; DNA Methylation; DNA, Plant; Dose-Response Relationship, Drug; Genome, Plant; Medicago sativa | 2009 |
Selected replicon variants with low-level in vitro resistance to the hepatitis C virus NS5B polymerase inhibitor PSI-6130 lack cross-resistance with R1479.
Topics: Antiviral Agents; Cell Line; Cytidine; Deoxycytidine; Drug Resistance, Viral; Genetic Variation; Hepacivirus; Humans; Molecular Sequence Data; Replicon; RNA-Dependent RNA Polymerase; Sequence Analysis, DNA; Viral Nonstructural Proteins | 2008 |
Cyclopentenyl cytosine has biological and anti-tumour activity, but does not enhance the efficacy of gemcitabine and radiation in two animal tumour models.
Topics: Animals; Antineoplastic Combined Chemotherapy Protocols; Cell Line, Tumor; Combined Modality Therapy; Cytidine; Cytidine Triphosphate; Deoxycytidine; Disease Models, Animal; Drug Synergism; Female; Gemcitabine; Humans; Lung Neoplasms; Mice; Mice, Nude; Middle Aged; Pancreatic Neoplasms; Rats; Rats, Inbred BN | 2009 |
DNA hairpins containing the cytidine analog pyrrolo-dC: structural, thermodynamic, and spectroscopic studies.
Topics: Cytidine; Dactinomycin; Deoxycytidine; DNA; Fluorescence; Fluorescence Resonance Energy Transfer; Inverted Repeat Sequences; Magnetic Resonance Spectroscopy; Models, Molecular; Nucleic Acid Conformation; Protein Conformation; Pyrroles; Thermodynamics; Titrimetry; Transition Temperature | 2009 |
DFT study of the interaction of cytidine and 2'-deoxycytidine with Li+, Na+, and K+: effects of metal cationization on sugar puckering and stability of the N-glycosidic bond.
Topics: Cations; Computers, Molecular; Cytidine; Deoxycytidine; Glycosylation; Lithium; Molecular Structure; Potassium; Ribonucleosides; Sodium | 2009 |
Origin of pyrimidine deoxyribonucleotide pools in perfused rat heart: implications for 3'-azido-3'-deoxythymidine-dependent cardiotoxicity.
Topics: Animals; Chromatography, High Pressure Liquid; Cytidine; Cytidine Triphosphate; Deoxyadenine Nucleotides; Deoxycytidine; Deoxycytosine Nucleotides; Deoxyguanine Nucleotides; Deoxyuridine; Heart; In Vitro Techniques; Male; Perfusion; Phosphorylation; Pyrimidine Nucleotides; Rats; Rats, Sprague-Dawley; Reverse Transcriptase Inhibitors; Thymine Nucleotides; Uracil; Uridine; Uridine Monophosphate; Uridine Triphosphate; Zidovudine | 2009 |
Fishing in the (deoxyribonucleotide) pool.
Topics: Animals; Antimetabolites; Cytidine; Cytidine Triphosphate; Deoxyadenine Nucleotides; Deoxycytidine; Deoxycytosine Nucleotides; Deoxyguanine Nucleotides; Deoxyuridine; Heart; Humans; Mitochondria; Mitochondrial Diseases; Models, Biological; Phosphorylation; Pyrimidine Nucleotides; Rats; Thymine Nucleotides; Uracil; Uridine; Uridine Monophosphate; Uridine Triphosphate; Zidovudine | 2009 |
Synthesis, crystallization, and biological evaluation of an orally active prodrug of gemcitabine.
Topics: Administration, Oral; Animals; Antineoplastic Agents; Cell Line, Tumor; Cell Transformation, Neoplastic; Colonic Neoplasms; Crystallization; Crystallography, X-Ray; Cytidine; Deoxycytidine; Gemcitabine; Humans; Mice; Models, Molecular; Molecular Conformation; Prodrugs; Solubility | 2009 |
Use of Drosophila deoxynucleoside kinase to study mechanism of toxicity and mutagenicity of deoxycytidine analogs in Escherichia coli.
Topics: Animals; Antineoplastic Agents; Azacitidine; Cytidine; Deoxycytidine; DNA; DNA Methylation; DNA Mismatch Repair; Drosophila melanogaster; Escherichia coli; Fluorescence; Microbial Sensitivity Tests; Mutagenesis; Phosphorylation; Phosphotransferases (Alcohol Group Acceptor) | 2010 |
Selective derivatization of cytosine and methylcytosine moieties with 2-bromoacetophenone for submicrogram DNA methylation analysis by reversed phase HPLC with spectrofluorimetric detection.
Topics: 5-Methylcytosine; Acetophenones; Animals; Chromatography, High Pressure Liquid; Chromatography, Reverse-Phase; Cytidine; Cytosine; Deoxycytidine; DNA Methylation; Fluorometry; Humans; Lepidium sativum; Oligochaeta; Salmon | 2011 |
Discovery of 4'-azido-2'-deoxy-2'-C-methyl cytidine and prodrugs thereof: a potent inhibitor of Hepatitis C virus replication.
Topics: Animals; Antiviral Agents; Cytidine; Deoxycytidine; Drug Discovery; Hepacivirus; Prodrugs; Rats; RNA-Dependent RNA Polymerase; Viral Nonstructural Proteins; Virus Replication | 2012 |
Antiviral activity of nucleoside analogues against norovirus.
Topics: Animals; Antiviral Agents; Cell Line, Tumor; Cytidine; Deoxycytidine; Dose-Response Relationship, Drug; Drug Evaluation, Preclinical; Drug Synergism; Gastroenteritis; Humans; Lamivudine; Mice; Norovirus; Ribavirin; RNA, Viral; Time Factors; Virus Replication | 2012 |
Consistent decrease in global DNA methylation and hydroxymethylation in the hippocampus of Alzheimer's disease patients.
Topics: Aged; Aged, 80 and over; Aging; Alzheimer Disease; Cytidine; Deoxycytidine; DNA Methylation; Epigenesis, Genetic; Female; Gene Expression Regulation, Developmental; Hippocampus; Humans; Hydroxylation; Male | 2013 |
Epigenetic switching by the metabolism-sensing factors in the generation of orexin neurons from mouse embryonic stem cells.
Topics: Acetylation; Animals; Cell Differentiation; Cytidine; Deoxycytidine; DNA Methylation; DNA-Cytosine Methylases; Embryonic Stem Cells; Epigenesis, Genetic; Female; Glycosylation; Hexosamines; Histone Deacetylase Inhibitors; Histones; Hydroxamic Acids; Intracellular Signaling Peptides and Proteins; Mice; Mice, Inbred C57BL; Neurons; Neuropeptides; Orexins; Protein Processing, Post-Translational; Sequence Analysis, DNA; Sirtuin 1; Spheroids, Cellular; Transcription Initiation Site | 2013 |
N-(guanidinoethyl)-2'-deoxy-5-methylisocytidine exhibits selective recognition of a CG interrupting site for the formation of anti-parallel triplexes.
Topics: Base Sequence; Cytidine; Deoxycytidine; DNA; Guanidines; Oligonucleotides; Substrate Specificity | 2013 |
Study on the interaction between bovine serum albumin and 4'-azido-2'-deoxyfluoroarabinocytidine or analogs by spectroscopy and molecular modeling.
Topics: Animals; Cattle; Cytidine; Deoxycytidine; Energy Transfer; Kinetics; Models, Molecular; Molecular Docking Simulation; Protein Binding; Serum Albumin, Bovine; Spectrometry, Fluorescence; Spectrophotometry, Ultraviolet; Temperature | 2014 |
Quantification of 2'-deoxy-2'-β-fluoro-4'-azidocytidine in rat and dog plasma using liquid chromatography-quadrupole time-of-flight and liquid chromatography-triple quadrupole mass spectrometry: Application to bioavailability and pharmacokinetic studies.
Topics: Animals; Biological Availability; Chromatography, High Pressure Liquid; Cytidine; Deoxycytidine; Dogs; Female; Lamivudine; Male; Mass Spectrometry; Plasma; Rats; Rats, Sprague-Dawley; Reference Standards | 2014 |
Optimizing HIV therapy. A consensus project on differences between cytidine analogues and regime compactness.
Topics: Adult; Anti-HIV Agents; Antiretroviral Therapy, Highly Active; Consensus; Cytidine; Delphi Technique; Deoxycytidine; Emtricitabine; Female; HIV Infections; HIV-1; Humans; Lamivudine; Male; Middle Aged; Practice Patterns, Physicians' | 2014 |
A novel cytidine analog, RX-3117, shows potent efficacy in xenograft models, even in tumors that are resistant to gemcitabine.
Topics: Administration, Oral; Animals; Antimetabolites, Antineoplastic; Cell Line, Tumor; Cytidine; Deoxycytidine; Disease Models, Animal; Drug Resistance, Neoplasm; Female; Gemcitabine; HCT116 Cells; HT29 Cells; Humans; Mice; Mice, Nude; Neoplasms; Xenograft Model Antitumor Assays | 2014 |
[Cytidine].
Topics: Antineoplastic Agents; Arabinonucleosides; Cytarabine; Cytidine; Deoxycytidine; Gemcitabine; Humans; Neoplasms | 2015 |
N3 and O2 protonated tautomeric conformations of 2'-deoxycytidine and cytidine coexist in the gas phase.
Topics: Cytidine; Deoxycytidine; Gases; Hydrogen; Least-Squares Analysis; Models, Chemical; Molecular Structure; Nitrogen; Oxygen; Protons; Spectrometry, Mass, Electrospray Ionization; Spectrophotometry, Infrared; Vibration | 2015 |
CDA directs metabolism of epigenetic nucleosides revealing a therapeutic window in cancer.
Topics: 5-Methylcytosine; Animals; Cell Death; Cell Line, Tumor; Cytidine; Cytidine Deaminase; Cytosine; Deoxycytidine; DNA; DNA Damage; DNA-Directed DNA Polymerase; Epigenesis, Genetic; Gene Expression Regulation, Enzymologic; Gene Expression Regulation, Neoplastic; Humans; Mice; Neoplasms; Nucleotides; Oxidation-Reduction; Phosphotransferases; Substrate Specificity; Up-Regulation; Uridine | 2015 |
Sensitive liquid chromatography mass spectrometry (LC-MS) assay reveals novel insights on DNA methylation and incorporation of gemcitabine, its metabolite difluorodeoxyuridine, deoxyuridine, and RX-3117 into DNA.
Topics: Cell Line, Tumor; Chromatography, Liquid; Cytidine; Deoxycytidine; DNA; DNA Methylation; Floxuridine; Gemcitabine; Humans; Limit of Detection; Mass Spectrometry; RNA | 2016 |
Extended exposure to substrate regulates the human equilibrative nucleoside transporter 1 (hENT1).
Topics: Antimetabolites, Antineoplastic; Binding Sites; Cytidine; Deoxycytidine; Equilibrative Nucleoside Transporter 1; Gemcitabine; HEK293 Cells; Humans; Protein Transport; Thioinosine | 2016 |
Excited State Decay Pathways of 2'-Deoxy-5-methylcytidine and Deoxycytidine Revisited in Solution: A Comprehensive Kinetic Study by Femtosecond Transient Absorption.
Topics: Acetonitriles; Cytidine; Deoxycytidine; DNA Damage; Kinetics; Quantum Theory; Solutions; Thermodynamics; Ultraviolet Rays | 2018 |
Structural basis for polymerase η-promoted resistance to the anticancer nucleoside analog cytarabine.
Topics: Antineoplastic Agents; Crystallization; Cytarabine; Cytidine; Deoxycytidine; DNA Repair; DNA Replication; DNA-Directed DNA Polymerase; Humans; Molecular Structure; X-Ray Diffraction | 2018 |
A novel malic acid-enhanced method for the analysis of 5-methyl-2'-deoxycytidine, 5-hydroxymethyl-2'-deoxycytidine, 5-methylcytidine and 5-hydroxymethylcytidine in human urine using hydrophilic interaction liquid chromatography-tandem mass spectrometry.
Topics: Chromatography, Liquid; Cytidine; Deoxycytidine; Humans; Hydrophobic and Hydrophilic Interactions; Malates; Nucleic Acid Conformation; Tandem Mass Spectrometry | 2018 |
Identification of novel compounds against Tat-mediated human immunodeficiency virus-1 transcription by high-throughput functional screening assay.
Topics: 3-Deazauridine; Anti-HIV Agents; Cell Line; Cytidine; Deoxycytidine; Drug Repositioning; Gemcitabine; High-Throughput Screening Assays; HIV-1; Humans; Roscovitine; Small Molecule Libraries; tat Gene Products, Human Immunodeficiency Virus; Transcription, Genetic; Virus Replication | 2020 |
Zebularine suppressed gemcitabine-induced senescence and improved the cellular and plasma pharmacokinetics of gemcitabine, augmented by liposomal co-delivery.
Topics: Animals; Cell Line, Tumor; Cytidine; Deoxycytidine; Drug Resistance, Neoplasm; Gemcitabine; Liposomes; Pancreatic Neoplasms; Rats | 2021 |
In vitro assessment of a synergistic combination of gemcitabine and zebularine in pancreatic cancer cells.
Topics: Antimetabolites, Antineoplastic; Apoptosis Regulatory Proteins; Carcinoma, Pancreatic Ductal; Cell Line, Tumor; Cytidine; Cytidine Deaminase; Deoxycytidine; Gemcitabine; Humans; Pancreas; Pancreatic Neoplasms | 2021 |
Role of Wnt/β-catenin pathway in cardiac lineage commitment of human umbilical cord mesenchymal stem cells by zebularine and 2'-deoxycytidine.
Topics: beta Catenin; Cell Differentiation; Cytidine; Deoxycytidine; Humans; Mesenchymal Stem Cells; Myocytes, Cardiac; Umbilical Cord; Wnt Signaling Pathway | 2022 |
Synthesis of Cy5-Labelled C5-Alkynyl-modified cytidine triphosphates via Sonogashira coupling for DNA labelling.
Topics: Cytidine; Cytidine Triphosphate; Deoxycytidine; DNA | 2023 |
Cytidine deaminases catalyze the conversion of
Topics: Cytidine; Cytidine Deaminase; Deoxycytidine; Pyrimidine Nucleosides; Uridine | 2023 |
Cell-free regeneration of ATP based on polyphosphate kinase 2 facilitates cytidine 5'-monophosphate production.
Topics: Adenosine Triphosphate; Cytidine; Cytidine Monophosphate; Deoxycytidine; Nucleoside-Phosphate Kinase; Nucleotides; Regeneration | 2023 |
Study of protonated dimers of cytosine, cytidine, and deoxycytidine using survival yield method and quantum mechanics calculations.
Topics: Cytidine; Cytosine; Deoxycytidine; Protons | 2023 |
A new technique for the analysis of metabolic pathways of cytidine analogues and cytidine deaminase activities in cells.
Topics: Cytidine; Cytidine Deaminase; DCMP Deaminase; Deoxycytidine; Deoxycytidine Kinase; Metabolic Networks and Pathways | 2023 |