Compounds > cytidine
Page last updated: 2024-08-17

cytidine and decitabine

cytidine has been researched along with decitabine in 34 studies

Research

Studies (34)

TimeframeStudies, this research(%)All Research%
pre-19902 (5.88)18.7374
1990's2 (5.88)18.2507
2000's14 (41.18)29.6817
2010's14 (41.18)24.3611
2020's2 (5.88)2.80

Authors

AuthorsStudies
Laliberté, J; Marquez, VE; Momparler, RL1
Bernheim, J; Buyssens, N; Cortvrindt, R; Roobol, K1
Jones, PA; Taylor, SM1
Bouffard, DY; Momparler, LF; Momparler, RL1
Leone, G; Lübbert, M; Teofili, L; Voso, MT1
Cheng, JC; Gonzales, FA; Hu, YG; Jones, PA; Liang, G; Marquez, VE; Weisenberger, DJ; Xu, GL1
Alleman, WG; Aprelikova, ON; Chandramouli, GV; Linehan, WM; Mendoza, A; Rodgers, C; Rogers, C; Sopko, NA; Tabios, RL; Torres-Cabala, C; Vasselli, JR1
Bernstein, ML; Lemaire, M; Marquez, VE; Momparler, LF; Momparler, RL1
Cherry, JC; Farrar, WL; Fox, SD; Hodge, DR; Hurt, EM; Kelley, JA; Munroe, DJ; Peng, B1
Balch, C; Craft, T; Huang, TH; Nephew, KP; Skalnik, DG; Yan, P; Young, S1
Chuang, JC; Jones, PA; Kwan, JM; Li, TW; Liang, G; Yang, AS; Yoo, CB1
Brueckner, B; Lyko, F; Musch, T; Stopper, H; Stresemann, C1
Chen, Y; Costa, E; Grayson, DR; Kundakovic, M1
Bernstein, ML; Lemaire, M; Momparler, LF; Momparler, RL; Raynal, NJ1
Issa, JP; Oki, Y1
Issa, JP1
Batz, C; Claus, R; Flotho, C; Ihde, S; Lübbert, M; Niemeyer, CM; Plass, C; Sandrock, I; Schneider, M1
Billam, M; Davidson, NE; Sobolewski, MD1
Assaraf, YG; Bram, EE; Raz, S; Stark, M1
Arimondo, PB; Champion, C; Guianvarc'h, D; Guieysse-Peugeot, AL; Jeltsch, A; Jurkowska, RZ; Ponger, L; Sénamaud-Beaufort, C1
Morales, JC; Rodríguez-Vargas, JM; Ruiz-Magaña, MJ; Ruiz-Ruiz, C; Saldivia, MA; Schulze-Osthoff, K1
Bianco-Miotto, T; Butler, LM; Centenera, MM; Chiam, K; Tilley, WD1
Barišić, D; Bosnar, MH; Horvat, T; Mužinić, A; Zoldoš, V1
Chie, EK; Kim, HJ; Kim, IA; Kim, IH; Kim, JH; Young, PD1
Chan, K; Covey, J; Ebrahem, Q; Engelke, KJ; Gu, X; Jankowska, A; Ling, Y; Maciejewski, J; Mahfouz, RZ; Radivoyevitch, T; Saunthararajah, Y; Sekeres, MA; Tabarroki, A; Terse, P; Tiu, R; Visconte, V1
Peng, M; Rothstein, SJ; Yaish, MW1
Flis, K; Flis, S; Gnyszka, A1
Arimany-Nardi, C; Errasti-Murugarren, E; Gorboulev, V; Koepsell, H; Martinez-Picado, J; Minuesa, G; Pastor-Anglada, M1
Campbell, RR; Dang, D; Ono, K; Schmidt, BL; Viet, CT; Ye, Y1
Levine, A; Sun, Y; Yi, L1
Anglard, P; Befort, K; Filliol, D; Fonteneau, M; Romieu, P; Zwiller, J1
Butter, R; Linnekamp, JF; Medema, JP; Spijker, R; van Laarhoven, HWM1
Dvořák Tomaštíková, E; Ercan, U; Finke, A; Krečmerová, M; Niezgodzki, I; Nowicka, A; Otmar, M; Pecinka, A; Poppenberger, B; Procházková, K; Rozhon, W; Schubert, I; Tokarz, B; Zwyrtková, J1
Abd Elmageed, ZY; Ali, HEA; Buttolph, T; Carraway, HE; Cen, Y; Denvir, J; Fan, J; Fandy, TE; Malkaram, SA; Primerano, DA; Shatnawi, A1

Reviews

3 review(s) available for cytidine and decitabine

ArticleYear
Inhibitors of DNA methylation in the treatment of hematological malignancies and MDS.
    Clinical immunology (Orlando, Fla.), 2003, Volume: 109, Issue:1

    Topics: Acetylation; Azacitidine; Cytidine; Decitabine; DNA Methylation; Hematologic Neoplasms; Histones; Humans; Leukemia, Myeloid; Myelodysplastic Syndromes

2003
Review: recent clinical trials in epigenetic therapy.
    Reviews on recent clinical trials, 2006, Volume: 1, Issue:2

    Topics: Animals; Antimetabolites, Antineoplastic; Azacitidine; Clinical Trials as Topic; Cytidine; Decitabine; DNA Methylation; Epigenesis, Genetic; Genetic Therapy; Histone Deacetylases; Humans; Myelodysplastic Syndromes

2006
Clinical and biological effects of demethylating agents on solid tumours - A systematic review.
    Cancer treatment reviews, 2017, Volume: 54

    Topics: Antimetabolites, Antineoplastic; Azacitidine; Cytidine; Decitabine; DNA Methylation; Humans; Hydralazine; Immune System; Methylation; Neoplasms; Procaine; Treatment Outcome

2017

Other Studies

31 other study(ies) available for cytidine and decitabine

ArticleYear
Potent inhibitors for the deamination of cytosine arabinoside and 5-aza-2'-deoxycytidine by human cytidine deaminase.
    Cancer chemotherapy and pharmacology, 1992, Volume: 30, Issue:1

    Topics: Antineoplastic Agents; Azacitidine; Azepines; Cytarabine; Cytidine; Cytidine Deaminase; Deamination; Decitabine; Humans; Kinetics; Pyrimidine Nucleosides; Tetrahydrouridine

1992
5-Azacytidine and 5-aza-2'-deoxycytidine behave as different antineoplastic agents in B16 melanoma.
    British journal of cancer, 1987, Volume: 56, Issue:3

    Topics: Animals; Antineoplastic Agents; Azacitidine; Cell Survival; Cells, Cultured; Cytidine; Decitabine; Drug Resistance; Melanoma; Mice; Mutation; Uridine

1987
Cellular differentiation, cytidine analogs and DNA methylation.
    Cell, 1980, Volume: 20, Issue:1

    Topics: Adipose Tissue; Animals; Azacitidine; Cell Differentiation; Cells, Cultured; Cytarabine; Cytidine; Decitabine; Deoxycytidine; DNA; DNA (Cytosine-5-)-Methyltransferases; Methylation; Methyltransferases; Mice; Muscles; Structure-Activity Relationship

1980
Enhancement of the antileukemic activity of 5-aza-2'-deoxycytidine by cyclopentenyl cytosine in HL-60 leukemic cells.
    Anti-cancer drugs, 1994, Volume: 5, Issue:2

    Topics: Antineoplastic Agents; Azacitidine; Cell Division; Cytidine; Cytidine Deaminase; Decitabine; Deoxycytosine Nucleotides; DNA, Neoplasm; Drug Synergism; Humans; Leukemia, Experimental; Tumor Cells, Cultured

1994
Continuous zebularine treatment effectively sustains demethylation in human bladder cancer cells.
    Molecular and cellular biology, 2004, Volume: 24, Issue:3

    Topics: Azacitidine; Cytidine; Decitabine; DNA; DNA (Cytosine-5-)-Methyltransferase 1; DNA (Cytosine-5-)-Methyltransferases; DNA Methylation; Enzyme Inhibitors; Gene Silencing; Genes, p16; Humans; Pyrimidine Nucleosides; Urinary Bladder Neoplasms

2004
The in vitro and in vivo effects of re-expressing methylated von Hippel-Lindau tumor suppressor gene in clear cell renal carcinoma with 5-aza-2'-deoxycytidine.
    Clinical cancer research : an official journal of the American Association for Cancer Research, 2004, Oct-15, Volume: 10, Issue:20

    Topics: Adenocarcinoma, Clear Cell; Animals; Antimetabolites, Antineoplastic; Azacitidine; Cytidine; Decitabine; Disease Models, Animal; DNA Methylation; Gene Silencing; Humans; Kidney Neoplasms; Mice; Pyrimidine Nucleosides; Reverse Transcriptase Polymerase Chain Reaction; Transfection; Transplantation, Heterologous; Tumor Cells, Cultured; Tumor Suppressor Proteins; Ubiquitin-Protein Ligases; Von Hippel-Lindau Tumor Suppressor Protein

2004
Enhancement of antineoplastic action of 5-aza-2'-deoxycytidine by zebularine on L1210 leukemia.
    Anti-cancer drugs, 2005, Volume: 16, Issue:3

    Topics: Animals; Antimetabolites, Antineoplastic; Azacitidine; Cell Line, Tumor; Cytidine; Cytidine Deaminase; Decitabine; DNA Methylation; Dose-Response Relationship, Drug; Drug Interactions; Humans; Leukemia L1210; Male; Mice; Pyrimidine Nucleosides; Reverse Transcriptase Polymerase Chain Reaction; Tumor Stem Cell Assay

2005
Interleukin 6 supports the maintenance of p53 tumor suppressor gene promoter methylation.
    Cancer research, 2005, Jun-01, Volume: 65, Issue:11

    Topics: Apoptosis; Azacitidine; Base Sequence; Cell Cycle; Cell Line, Tumor; Cytidine; Decitabine; Deoxycytidine; DNA (Cytosine-5-)-Methyltransferase 1; DNA (Cytosine-5-)-Methyltransferases; DNA Methylation; Gene Silencing; Genes, p53; Humans; Interleukin-6; Molecular Sequence Data; Multiple Myeloma; Promoter Regions, Genetic; Sulfites; Tumor Suppressor Protein p53

2005
Antimitogenic and chemosensitizing effects of the methylation inhibitor zebularine in ovarian cancer.
    Molecular cancer therapeutics, 2005, Volume: 4, Issue:10

    Topics: Antineoplastic Combined Chemotherapy Protocols; Azacitidine; Cell Growth Processes; Cell Line, Tumor; Cisplatin; Cytidine; Decitabine; DNA Methylation; Drug Synergism; Female; Gene Expression Regulation, Neoplastic; Gene Silencing; Genes, Tumor Suppressor; Humans; Ovarian Neoplasms

2005
Comparison of biological effects of non-nucleoside DNA methylation inhibitors versus 5-aza-2'-deoxycytidine.
    Molecular cancer therapeutics, 2005, Volume: 4, Issue:10

    Topics: Antimetabolites, Antineoplastic; Azacitidine; Carcinoma, Transitional Cell; Catechin; Cell Line, Tumor; Colorectal Neoplasms; Cytidine; Decitabine; Deoxycytidine; DNA Methylation; DNA Modification Methylases; Enzyme Inhibitors; Female; Gene Silencing; HT29 Cells; Humans; Hydralazine; Male; Procainamide; Prostatic Neoplasms; Reverse Transcriptase Polymerase Chain Reaction

2005
Functional diversity of DNA methyltransferase inhibitors in human cancer cell lines.
    Cancer research, 2006, Mar-01, Volume: 66, Issue:5

    Topics: Azacitidine; Catechin; Cell Line, Tumor; Cytidine; Decitabine; DNA (Cytosine-5-)-Methyltransferases; DNA Methylation; Enzyme Inhibitors; Humans; Indoles; Jurkat Cells; Phthalimides; Procaine; Propionates; Tryptophan

2006
DNA methyltransferase inhibitors coordinately induce expression of the human reelin and glutamic acid decarboxylase 67 genes.
    Molecular pharmacology, 2007, Volume: 71, Issue:3

    Topics: Acetylation; Azacitidine; Cell Adhesion Molecules, Neuronal; Cells, Cultured; Cytidine; Decitabine; DNA (Cytosine-5-)-Methyltransferase 1; DNA (Cytosine-5-)-Methyltransferases; Dose-Response Relationship, Drug; Doxorubicin; Enzyme Inhibitors; Extracellular Matrix Proteins; Gene Expression Regulation; Glutamate Decarboxylase; Histones; Humans; Isoenzymes; Methyl-CpG-Binding Protein 2; Nerve Tissue Proteins; Reelin Protein; RNA, Messenger; Serine Endopeptidases

2007
Inhibition of cytidine deaminase by zebularine enhances the antineoplastic action of 5-aza-2'-deoxycytidine.
    Cancer chemotherapy and pharmacology, 2009, Volume: 63, Issue:3

    Topics: 3T3 Cells; Animals; Antineoplastic Agents; Azacitidine; Cytidine; Cytidine Deaminase; Decitabine; Drug Synergism; Enzyme Inhibitors; Leukemia, Experimental; Male; Mice; Mice, Inbred BALB C; Mice, Inbred DBA

2009
Cancer prevention: epigenetics steps up to the plate.
    Cancer prevention research (Philadelphia, Pa.), 2008, Volume: 1, Issue:4

    Topics: Antimetabolites, Antineoplastic; Azacitidine; Cell Transformation, Neoplastic; Chemoprevention; Cytidine; Decitabine; DNA (Cytosine-5-)-Methyltransferases; DNA Methylation; Enzyme Inhibitors; Epigenesis, Genetic; Humans; Models, Biological; Neoplasms

2008
The DNA methyltransferase inhibitors azacitidine, decitabine and zebularine exert differential effects on cancer gene expression in acute myeloid leukemia cells.
    Leukemia, 2009, Volume: 23, Issue:6

    Topics: Antimetabolites, Antineoplastic; Apoptosis; Azacitidine; Cell Differentiation; Cell Line, Tumor; Cell Proliferation; Cytidine; Decitabine; DNA Methylation; DNA Modification Methylases; Enzyme Inhibitors; Gene Expression Profiling; Gene Expression Regulation, Neoplastic; Humans; Leukemia, Myeloid, Acute

2009
Effects of a novel DNA methyltransferase inhibitor zebularine on human breast cancer cells.
    Breast cancer research and treatment, 2010, Volume: 120, Issue:3

    Topics: Adenocarcinoma; Apoptosis Regulatory Proteins; Azacitidine; Breast Neoplasms; Cell Cycle Proteins; Cell Line, Tumor; Chromatin Immunoprecipitation; Cytidine; Cytidine Deaminase; Decitabine; DNA (Cytosine-5-)-Methyltransferases; Dose-Response Relationship, Drug; Drug Screening Assays, Antitumor; Drug Synergism; Enzyme Inhibitors; Female; Gene Expression Regulation, Neoplastic; Humans; Hydroxamic Acids; Neoplasm Proteins; Receptors, Estrogen; S Phase; Tumor Stem Cell Assay; Vorinostat

2010
Chemotherapeutic drug-induced ABCG2 promoter demethylation as a novel mechanism of acquired multidrug resistance.
    Neoplasia (New York, N.Y.), 2009, Volume: 11, Issue:12

    Topics: Antineoplastic Agents; ATP Binding Cassette Transporter, Subfamily G, Member 2; ATP-Binding Cassette Transporters; Azacitidine; Cell Line, Tumor; Cell Proliferation; Cytidine; Decitabine; DNA Methylation; Drug Resistance, Neoplasm; Gene Expression Regulation, Neoplastic; Humans; Jurkat Cells; K562 Cells; Neoplasm Proteins; Precursor T-Cell Lymphoblastic Leukemia-Lymphoma; Promoter Regions, Genetic; Reverse Transcriptase Polymerase Chain Reaction

2009
Mechanistic insights on the inhibition of c5 DNA methyltransferases by zebularine.
    PloS one, 2010, Aug-24, Volume: 5, Issue:8

    Topics: Animals; Azacitidine; Base Sequence; Cytidine; Decitabine; DNA; DNA (Cytosine-5-)-Methyltransferases; Enzyme Inhibitors; Humans; Methylation; Mice

2010
The DNA methyltransferase inhibitors zebularine and decitabine induce mitochondria-mediated apoptosis and DNA damage in p53 mutant leukemic T cells.
    International journal of cancer, 2012, Mar-01, Volume: 130, Issue:5

    Topics: Apoptosis; Azacitidine; Caspase 9; Cell Cycle; Cell Line, Tumor; Cytidine; Decitabine; DNA (Cytosine-5-)-Methyltransferases; DNA Damage; Genes, p53; Humans; Leukemia, T-Cell; Mitochondria; Mutation; Reactive Oxygen Species; T-Lymphocytes

2012
GSTP1 DNA methylation and expression status is indicative of 5-aza-2'-deoxycytidine efficacy in human prostate cancer cells.
    PloS one, 2011, Volume: 6, Issue:9

    Topics: Azacitidine; Biomarkers, Tumor; Cell Death; Cell Line, Tumor; Cell Proliferation; Cell Survival; Cytidine; Decitabine; DNA Methylation; Dose-Response Relationship, Drug; Drug Discovery; Enzyme Inhibitors; Gene Expression Regulation, Neoplastic; Gene Silencing; Glutathione S-Transferase pi; Humans; Male; Promoter Regions, Genetic; Prostate-Specific Antigen; Prostatic Neoplasms; Time Factors

2011
Epigenetic modulation of the HeLa cell membrane N-glycome.
    Biochimica et biophysica acta, 2012, Volume: 1820, Issue:9

    Topics: Antineoplastic Agents; Azacitidine; Butyrates; Carbohydrate Sequence; Cytidine; Decitabine; DNA Methylation; Epigenesis, Genetic; Gene Expression Regulation, Neoplastic; Glycomics; HeLa Cells; Histone Deacetylase Inhibitors; Humans; Hydroxamic Acids; Molecular Sequence Data; Polysaccharides

2012
DNMT (DNA methyltransferase) inhibitors radiosensitize human cancer cells by suppressing DNA repair activity.
    Radiation oncology (London, England), 2012, Mar-20, Volume: 7

    Topics: Azacitidine; Caspase 3; Catechin; Cell Line, Tumor; Cytidine; Decitabine; Disulfides; DNA (Cytosine-5-)-Methyltransferase 1; DNA (Cytosine-5-)-Methyltransferases; DNA Breaks, Double-Stranded; DNA Methyltransferase 3A; DNA Methyltransferase 3B; DNA Repair; Enzyme Induction; Gene Expression Regulation, Neoplastic; Glioblastoma; Histones; Humans; Hydralazine; Inhibitory Concentration 50; Lung Neoplasms; Neoplasm Proteins; Radiation-Sensitizing Agents; Tumor Stem Cell Assay; Tyrosine

2012
Increased CDA expression/activity in males contributes to decreased cytidine analog half-life and likely contributes to worse outcomes with 5-azacytidine or decitabine therapy.
    Clinical cancer research : an official journal of the American Association for Cancer Research, 2013, Feb-15, Volume: 19, Issue:4

    Topics: Animals; Azacitidine; Cytarabine; Cytidine; Cytidine Deaminase; Decitabine; DNA (Cytosine-5-)-Methyltransferase 1; DNA (Cytosine-5-)-Methyltransferases; Female; Gene Expression Regulation, Neoplastic; Humans; Leukemia, Myeloid, Acute; Male; Mice; Myelodysplastic Syndromes; Polymorphism, Single Nucleotide; Survival Analysis; Treatment Outcome

2013
Global DNA methylation analysis using methyl-sensitive amplification polymorphism (MSAP).
    Methods in molecular biology (Clifton, N.J.), 2014, Volume: 1062

    Topics: Arabidopsis; Azacitidine; Base Sequence; Cytidine; Decitabine; DNA Methylation; DNA, Plant; Polymerase Chain Reaction; Polymorphism, Genetic; Seeds

2014
DNA methyltransferase inhibitors improve the effect of chemotherapeutic agents in SW48 and HT-29 colorectal cancer cells.
    PloS one, 2014, Volume: 9, Issue:3

    Topics: Antineoplastic Combined Chemotherapy Protocols; Apoptosis; Azacitidine; Cell Cycle; Cell Line, Tumor; Colorectal Neoplasms; Cytidine; Decitabine; DNA Damage; DNA-Cytosine Methylases; Enzyme Inhibitors; Fluorouracil; Humans; Membrane Potential, Mitochondrial; Organoplatinum Compounds; Oxaliplatin

2014
Nucleoside transporters and human organic cation transporter 1 determine the cellular handling of DNA-methyltransferase inhibitors.
    British journal of pharmacology, 2014, Volume: 171, Issue:16

    Topics: Animals; Azacitidine; Biological Transport; Cell Survival; Cytidine; Decitabine; DNA Modification Methylases; Dogs; HeLa Cells; Humans; Madin Darby Canine Kidney Cells; Nucleoside Transport Proteins; Oocytes; Organic Cation Transporter 1; Xenopus laevis

2014
Demethylating drugs as novel analgesics for cancer pain.
    Clinical cancer research : an official journal of the American Association for Cancer Research, 2014, Sep-15, Volume: 20, Issue:18

    Topics: Analgesics, Opioid; Animals; Antineoplastic Agents; Azacitidine; Carcinoma, Squamous Cell; Cytidine; Decitabine; Disease Models, Animal; DNA Methylation; Heterografts; Humans; Immunohistochemistry; In Situ Hybridization; Mice; Mouth Neoplasms; Neurons; Pain; Receptors, Opioid, mu; Reverse Transcriptase Polymerase Chain Reaction; Transduction, Genetic; Trigeminal Ganglion

2014
Selected drugs that inhibit DNA methylation can preferentially kill p53 deficient cells.
    Oncotarget, 2014, Oct-15, Volume: 5, Issue:19

    Topics: Animals; Anticarcinogenic Agents; Azacitidine; Catechin; Cell Line, Tumor; Cell Proliferation; Cytidine; Decitabine; DNA Methylation; Humans; Lung Neoplasms; Mice; Mice, Inbred C57BL; Mice, Knockout; Mutation; Neoplasm Transplantation; Phthalimides; Tryptophan; Tumor Suppressor Protein p53; Xenograft Model Antitumor Assays

2014
Inhibition of DNA methyltransferases regulates cocaine self-administration by rats: a genome-wide DNA methylation study.
    Genes, brain, and behavior, 2017, Volume: 16, Issue:3

    Topics: Animals; Azacitidine; Brain; Cocaine; Cocaine-Related Disorders; CpG Islands; Cytidine; Decitabine; DNA; DNA Methylation; DNA Modification Methylases; Enzyme Inhibitors; Epigenesis, Genetic; Genome; Male; Phosphatidylinositol 3-Kinases; Promoter Regions, Genetic; Rats; Rats, Wistar; Reinforcement, Psychology; Self Administration

2017
Comparative analysis of epigenetic inhibitors reveals different degrees of interference with transcriptional gene silencing and induction of DNA damage.
    The Plant journal : for cell and molecular biology, 2020, Volume: 102, Issue:1

    Topics: Adenosine; Arabidopsis; Azacitidine; Chromosome Aberrations; Cytidine; Decitabine; DNA Damage; DNA Methylation; DNA Repair; Epigenesis, Genetic; Gene Silencing; Heterochromatin; RNA Interference; Tandem Repeat Sequences

2020
Activation of SIRT6 by DNA hypomethylating agents and clinical consequences on combination therapy in leukemia.
    Scientific reports, 2020, 06-25, Volume: 10, Issue:1

    Topics: Acetylation; Antimetabolites, Antineoplastic; Antineoplastic Combined Chemotherapy Protocols; Azacitidine; Bone Marrow; Cell Line, Tumor; Cytidine; Decitabine; DNA Methylation; Histones; Humans; Leukemia, Myeloid, Acute; Sirtuins

2020