Page last updated: 2024-08-17

cytidine and balapiravir

cytidine has been researched along with balapiravir in 7 studies

Research

Studies (7)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's4 (57.14)29.6817
2010's3 (42.86)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Berns, H; Cooksley, G; Dore, GJ; Hill, G; Klumpp, K; Najera, I; Roberts, SK; Robson, R; Shaw, D; Washington, C1
Chan, A; Everson, GT; Fried, MW; Ghalib, R; Godofsky, E; Harrison, S; Hill, G; Najera, I; Nelson, D; Nyberg, L; Pockros, PJ; Rodriguez-Torres, M; Shiffman, ML1
Alfredson, T; Birudaraj, R; Brandl, M; Hadig, X; Hill, G; Holper, M; Hong, L; Jia, Z; Larrabee, S; Reddy, M; Sarma, K; Smith, DB; Tran, T; Washington, C; Wu, X1
Kronenberger, B; Zeuzem, S1
Alfredson, T; Brandl, M; Hadig, X; Hong, L; Huang, S; Li, F; Tran, T; Wu, X1
Abdul Ghafar, N; Blasco, F; Cerny, D; Chen, YL; Fink, K; Fu, Y; Gu, F; Herve, M; Karuna, R; Lim, SP; Schul, W; Shi, PY; Wang, G; Yokohama, F1
Behera, I; Beigelman, L; Chaudhuri, S; Deval, J; Dyatkina, N; Jekle, A; Jin, Z; Kinkade, A; Rajwanshi, VK; Smith, DB; Symons, JA; Tucker, K; Wang, G1

Reviews

1 review(s) available for cytidine and balapiravir

ArticleYear
Future treatment options for HCV: double, triple, what is the optimal combination?
    Best practice & research. Clinical gastroenterology, 2008, Volume: 22, Issue:6

    Topics: Antiviral Agents; Cytidine; DNA-Directed RNA Polymerases; Drug Delivery Systems; Drug Resistance, Viral; Drug Therapy, Combination; Forecasting; Hepatitis C, Chronic; Humans; Interferon alpha-2; Interferon-alpha; Nucleosides; Oligopeptides; Polyethylene Glycols; Prodrugs; Proline; Protease Inhibitors; Pyrimidine Nucleosides; Recombinant Proteins; Ribavirin

2008

Trials

2 trial(s) available for cytidine and balapiravir

ArticleYear
Robust antiviral activity of R1626, a novel nucleoside analog: a randomized, placebo-controlled study in patients with chronic hepatitis C.
    Hepatology (Baltimore, Md.), 2008, Volume: 48, Issue:2

    Topics: Adult; Alanine Transaminase; Antiviral Agents; Cytidine; Dose-Response Relationship, Drug; Drug Resistance, Viral; Female; Hepacivirus; Hepatitis C, Chronic; Humans; Male; Middle Aged; Nucleosides; Prodrugs; RNA, Viral; Single-Blind Method; Time Factors; Viral Load

2008
R1626 plus peginterferon Alfa-2a provides potent suppression of hepatitis C virus RNA and significant antiviral synergy in combination with ribavirin.
    Hepatology (Baltimore, Md.), 2008, Volume: 48, Issue:2

    Topics: Adult; Aged; Aged, 80 and over; Alanine Transaminase; Antiviral Agents; Cytidine; Dose-Response Relationship, Drug; Double-Blind Method; Drug Resistance, Viral; Drug Synergism; Drug Therapy, Combination; Female; Hepacivirus; Humans; Interferon alpha-2; Interferon-alpha; Male; Middle Aged; Neutropenia; Nucleosides; Polyethylene Glycols; Prodrugs; Recombinant Proteins; Ribavirin; RNA, Viral; Treatment Outcome; Viral Load

2008

Other Studies

4 other study(ies) available for cytidine and balapiravir

ArticleYear
Physicochemical properties of the nucleoside prodrug R1626 leading to high oral bioavailability.
    Drug development and industrial pharmacy, 2008, Volume: 34, Issue:7

    Topics: Antiviral Agents; Biological Availability; Caco-2 Cells; Cytidine; DNA-Directed RNA Polymerases; Dose-Response Relationship, Drug; Drug Stability; Hepacivirus; Humans; Hydrolysis; Nucleosides; Particle Size; Permeability; Prodrugs; Solubility; Viral Nonstructural Proteins

2008
Chemical stability of 4'-azidocytidine and its prodrug balapiravir.
    Drug development and industrial pharmacy, 2010, Volume: 36, Issue:4

    Topics: Antiviral Agents; Azides; Chemical Phenomena; Cytidine; Drug Stability; Hydrogen-Ion Concentration; Nucleosides; Prodrugs

2010
Activation of peripheral blood mononuclear cells by dengue virus infection depotentiates balapiravir.
    Journal of virology, 2014, Volume: 88, Issue:3

    Topics: Animals; Antiviral Agents; Cytidine; Cytokines; Dengue; Dengue Virus; Female; Humans; Leukocytes, Mononuclear; Mice; Nucleosides; Prodrugs

2014
Structure-activity relationship analysis of mitochondrial toxicity caused by antiviral ribonucleoside analogs.
    Antiviral research, 2017, Volume: 143

    Topics: Adenosine; Amides; Antiviral Agents; Cell Line; Cytidine; DNA-Directed RNA Polymerases; Guanosine Monophosphate; Humans; Inhibitory Concentration 50; Mitochondria; Mitochondrial Proteins; Nucleosides; Prodrugs; Protein Biosynthesis; Pyrazines; Ribonucleosides; RNA; RNA, Mitochondrial; Sofosbuvir; Structure-Activity Relationship; Transcription Initiation Site; Transcription, Genetic

2017