cytellin and skimmianine

One novel compound was isolated from the hexane extract of Choisya ternata Kunth. leaves, choisyaternatine (1), together with the known compounds tecleamaniensine A (2), lup-20(29)-en-3β-ol (lupeol) (3), lup-20(29)-en-3β,24-diol (4), β-sitosterol glucoside (5), and skimmianine (6), plus the following known compounds from the dichloromethane extract, choisyine (7) and 6-methoxy-7,8-methylenedioxycoumarin (8). Compounds 2-5 are reported for the first time in this species. The structures of isolated compounds were elucidated by extensive spectroscopic analyses and comparison with previously reported spectroscopic data. The structure of choisyaternatine was further confirmed based on X-ray data analysis.

Topics: Alkaloids; Crystallography, X-Ray; Glucosides; Molecular Structure; Pentacyclic Triterpenes; Plant Extracts; Plant Leaves; Quinolines; Rutaceae; Sitosterols

Leaves and wood of Peltostigma guatemalense, a novel species of the family Rutaceae, yielded a total of 14 secondary metabolites, i.e. methyl p-hydroxy benzoate, phenylacetic acid, beta-sitosterol, lupeol, syringaresinol, scopoletin, gardenin B (1), and seven alkaloids: gamma-fagarine (2), skimmianine (3), kokusaginine (4), 7-O-isopentenyl-gamma-fagarine (5), anhydro-evoxine (6), evoxine (7) and 4-methoxy-1-methyl-quinolin-2-one (8). The compounds have been identified by spectroscopic methods. Antibacterial and antimalarial in vitro activity of the isolated compounds were also determined. Methyl p-hydroxy benzoate and quinolone (8) were the most effective on Plasmodium falciparium strains.

Topics: Alkaloids; Animals; Anti-Bacterial Agents; Antimalarials; Bacteria; Furans; Lignans; Magnetic Resonance Spectroscopy; Molecular Structure; Pentacyclic Triterpenes; Plant Extracts; Plasmodium falciparum; Quinolines; Rutaceae; Sitosterols; Triterpenes

Topics: Antineoplastic Agents, Phytogenic; Chromatography; Costa Rica; Furocoumarins; Magnetic Resonance Spectroscopy; Methoxsalen; Plant Extracts; Plant Stems; Quinolines; Sitosterols; Trees; Tumor Cells, Cultured; X-Ray Diffraction