cytellin and sericic-acid

Vochysia divergens Pohl (Vochysiaceae) is a tree commonly found in wet soils of 'Pantanal' of Mato Grosso, Brazil, and used in folk medicine against infections and asthma. We have studied different extracts and some isolated compounds from this plant for antibacterial activity. From the extracts of the stem bark beta-sitosterol, betulinic acid and sericic acid were isolated. The minimal inhibitory concentration (MIC) for Staphylococcus aureus were: ethanolic extract (MIC = 1.5 mg/ml); ethyl acetate extract (MIC = 2.0 mg/ml); and sericic acid (MIC = 1.0 mg/ml). Escherichia coli was resistant until 5 mg/ml.

Topics: Anti-Bacterial Agents; Antineoplastic Agents, Phytogenic; Betulinic Acid; Brazil; Escherichia coli; Magnetic Resonance Spectroscopy; Medicine, Traditional; Microbial Sensitivity Tests; Oleanolic Acid; Pentacyclic Triterpenes; Plant Extracts; Plant Stems; Sitosterols; Spectrophotometry, Infrared; Staphylococcus aureus; Triterpenes