cytellin and physcione

To investigate the chemical constituents of Rubus alceaefolius.. Nine compounds were isolated and purified from the petroleum ether extract of 95% alcohol extract of Rubus alceaefolius by repeated column chromatography on silica, Sephadex LH-20 and structurally identified by spectral analysis.. The compounds were identified as chrysophanol(1), physcion (2), β-sitosterol(3), 3-oxotirucalla-7, 24-dien-21-oic acid(4), myricadiol(5), 19-α-hydroxy-3-acetyl-ursolic acid(6), N-benzoylphenylalaninyl-N-benzoylphenylalaninate(7), aurantiamide acetate(8) and euscaphic acid(9).. Compounds land 4~8 are isolated from this plant for the first time, and compounds 4 - 8 are found in plants of Rubus genus for the first time.

Topics: Dipeptides; Emodin; Phytochemicals; Plant Extracts; Rubus; Sitosterols; Solvents; Triterpenes

To study the chemical constituents from Kalimeris indica.. Compounds were isolated and purified with silica gel and Sephadex LH-20 column chromatography, their structures were determined by using spectroscopic analysis including MS and NMR.. Nine compounds were isolated and identified as tritriacontane (I), hexadecanol (II), chrysophanol (III), vanillin (IV), physcion (V), beta-sitosterol (VI), stigmasterol (VII), leinoleic acid (VII), emodin (IX).. All of them, except compound IV, VI, are isolated from this genus for the first time. Compound III, IV had the protective effects with the toxicity of CCl4 on primary cultered hepatocytes.

Topics: Anthraquinones; Anti-Inflammatory Agents; Asteraceae; Benzaldehydes; Carbon Tetrachloride; Cell Survival; Cells, Cultured; Chemical and Drug Induced Liver Injury; Emodin; Fatty Alcohols; Hepatocytes; Magnetic Resonance Spectroscopy; Paraffin; Plants, Medicinal; Sitosterols

To study the chemical constituents and volatile oil of Xiaochengqi decoction.. The constituents in decoction were separated by means of column chromatography and their structures were identified by spectral data and compared with literature data. As well as the volatile oil of Xiaochengqi Fang were analyzed and identified by GC-MS.. Eleven compounds were isolated and identified as chrysophanol (1), physcion (2), magnolol (3), beta-sitosterol (4), sitosterol trans-cinnamic acid (5), emodin (6), aloe emodin (7), rhein (8), gallic acid (9), chrysophanol-8-O-beta-D-glucopyranoside (10), aurantiamarin (11). The volatile oils extracted with steam distillation from Xiaochengqi were identified 67 components, and the main components are including.. All of the eleven compounds were isolated from Xiaochengqi decoction for the first time and the study on their activities in Chinese prescription is being carried out. D-limonene (42.61%), p-cymene (16.43%), and 8-terpinene (14.46%).

Topics: Anthraquinones; Biphenyl Compounds; Cinnamates; Cyclohexenes; Cymenes; Drugs, Chinese Herbal; Emodin; Gallic Acid; Gas Chromatography-Mass Spectrometry; Lignans; Limonene; Monoterpenes; Oils, Volatile; Sitosterols; Terpenes

To study the chemical constituents of Rhizoma Cyperi.. The constituents were separated and purified by silica gel column chromatography, their structures were identified on the basis of physico-chemical properties and spectral data.. Six compounds were isolated and identified as physicion (1), hexadecanoic acid (2), beta-sitosterol (3), stigmasterol (4), catenarin (5), daucosterol (6).. Compounds 1, 4, 5 were isolated from this plant for the first fime.

Topics: Cyperus; Emodin; Magnetic Resonance Spectroscopy; Palmitic Acid; Plants, Medicinal; Rhizome; Sitosterols; Spectrophotometry, Ultraviolet; Stigmasterol

A new chalcone glycoside, chalcone-2',4-dihydroxy-4'-O-beta-D-glucoside has been isolated from Rhamnus nipalensis together with sitosterol, lupeol, di-O-methyldaidzein, kaempferol-4'-methylether, quercetin, physcion, sitosterol glucoside, emodin and their structures established by spectroscopic data. Isolation of these compounds are the first report from this plant.

Topics: Chalcones; Emodin; Glucosides; India; Kaempferols; Molecular Structure; Nuclear Magnetic Resonance, Biomolecular; Pentacyclic Triterpenes; Plants, Medicinal; Quercetin; Rhamnus; Sitosterols; Triterpenes

A new isocoumarin, annulatomarin (1), together with the known physcion and beta-sitosterol were isolated from the aerial parts of Hypericum annulatum. The structure of the new compound was established as 6,8-dihydroxy-7-methoxy-3-phenyl-3,4-dihydro-1H-isochromen-1-one on the basis of detailed spectroscopic analysis. Annulatomarin exhibited a modest growth-inhibitory activity in vitro against human chronic myeloid leukaemia LAMA-84 cells with an IC(50) = 111 microM.

Topics: Cell Line, Tumor; Emodin; Humans; Hypericum; Inhibitory Concentration 50; Isocoumarins; Molecular Biology; Sitosterols