cytellin and eupatilin

To study the chemical constituents from the leaves of "Chuju" Chrysanthemum morifolium.. All compounds were separated and purified by column chromatography over silica gel, Sephadex LH-20 and preparative HPLC. Their structures were identified by spectral methods including 1H-NMR and 13C-NMR.. 21 compounds were isolated and identified as octa-cosyl alcohol (1), β-sitosterol (2), lupeol (3), α-amyrin (4), daucosterol (5), ineupatorolide B (6), syringin (7), chlorogenic acid (8), petasiphenol (9), physcion (10), acacetin (11), eupatilin (12), quercetin (13), diosmetin (14), luteolin (15), apigenin (16), apigenin- 7-O-β-D-glucopyranoside (17), quercetin-3-O-β-D-glucopyranoside (18), luteolin-7-O-β-D-gluco pyranoside (19), apigenin-7-O-β-D- neospheroside (20), and acacetin-7-O-β-D-glucoside (21).. Compounds 1-12, 18 and 20 are isolated from this plant for the first time. Compounds 10, 13, 14, 15 and 16 have shown strong antioxidant activities by DPPH · scavenging activity better than Vit C.

Topics: Antioxidants; Apigenin; Chlorogenic Acid; Chrysanthemum; Flavones; Flavonoids; Glucosides; Luteolin; Phenylpropionates; Phytochemicals; Plant Leaves; Plants, Medicinal; Quercetin; Sitosterols

beta-Sitosterol and eupatilin were isolated and identified from Artemisia argyi. Both of them showed marked inhibition of platelet aggregation.

Topics: Drugs, Chinese Herbal; Flavonoids; Platelet Aggregation Inhibitors; Sitosterols