cytellin and acetylaleuritolic-acid

To study the chemical constituents of Mallotus paniculaus radix.. The compounds were isolated with column chromatography. The chemical structures were identified by spectral and spectroscopic technology.. Seven compounds were isolated from the n-BuOH extract and identified as scopoletin(1), isoscopletin(2), erythordiol(3), apigenin(4), 4-methoxybenzoic acid(5), acetylaleuritolic acid(6) and β-daucosterol (7).. compounds 2 - 6 are isolated from this plant for the first time.

Topics: Apigenin; Mallotus Plant; Phytochemicals; Plant Roots; Scopoletin; Sitosterols; Triterpenes

Jatropha isabellei Müll Arg. belongs to the family Euphorbiaceae. The antioxidant capacity of this plant was evaluated by the DPPH method and inhibition of thiobarbituric acid reactive substances (TBARS). Ethyl acetate fraction demonstrated the best antioxidant capacity against the DPPH free radical and its profile was similar to ascorbic acid. This fraction also presented the best results of phenolics, flavonoids and condensed tannins, showing a positive relation between the phenolic content and antioxidant activity. All fractions and the crude extract were able to inhibit significantly the TBARS production induced by Fe(II) for the two tested concentrations, reaching the basal levels. In this test, ethyl acetate and dichloromethane fraction showed good values for inhibitory concentration. The dichloromethane fraction showed the best results against the fungi Sporothrix schenckii and Fusarium proliferatum and the bacterium of Micrococcus genus. This fraction allowed the isolation of acetil aleuritolic acid and a mixture of sitosterol 3-O-β-D-glucoside and stigmasterol, described for the first time in this species.

Topics: Animals; Anti-Infective Agents; Antioxidants; Brain; Drug Evaluation, Preclinical; Flavonoids; Free Radical Scavengers; Fusarium; Glucosides; Jatropha; Lipid Peroxidation; Male; Molecular Structure; Phenols; Plant Extracts; Rats, Wistar; Sitosterols; Sporothrix; Stigmasterol; Tannins; Thiobarbituric Acid Reactive Substances; Triterpenes

To study the chemical constituents of Excoecaria agallocha L.. The constituents were isolated and purified by repeated column chromatography and their structures were elucidated by spectroscopic analysis.. Six triterpenoids including taraxerone (1), beta-amyrin acetate (2), 3beta-[(2E,4E)-6-oxo-decadienoyloxy]-olean-12-ene (3), taraxerol (4), acetylaleuritolic acid (5), and cycloart-22-ene-3beta, 25-diol (6), and three steroids including beta-sitostenone (7), (24R)-24-ethylcholesta-4,22-dien-3-one (8), and beta-sitosterol (9) were isolated and identified from the stems and twigs of the mangrove plant E. agallocha.. Compounds 5-8 were isolated from E. agallocha for the first time.

Topics: Euphorbiaceae; Magnetic Resonance Spectroscopy; Oleanolic Acid; Sitosterols; Steroids; Triterpenes