cytellin and 3-4-5-trimethoxybenzoic-acid

cytellin has been researched along with 3-4-5-trimethoxybenzoic-acid* in 1 studies

Other Studies

1 other study(ies) available for cytellin and 3-4-5-trimethoxybenzoic-acid

Article	Year
(+)-rumphiin and polyalthurea, new compounds from the stems of Polyalthia rumphii. Natural product communications, 2013, Volume: 8, Issue:10 Two new compounds, (+)-rumphiin (3) and polyalthurea (7), together with seven known ones, 3,4,5-trimethoxy benzoic acid (1), (-)-seselinone (2), cannabisin D (4), allantoin (5), oxostephanine (6) and a mixture of beta-sitosterol (8) and stigmasterol (9) were isolated from the stems of Polyalthia rumphii. The chemical structures of 3 and 7 were elucidated by the combination of spectroscopic data, and the absolute configuration of 3 at C-2 was determined by the matrix method to be R. All compounds were evaluated for their cytotoxicity on four human cancer cell lines, which demonstrated that 3 was a moderate bioactive lignan, and 6 showed significant anticancer activity against SPC-A-1 and BEL-7402 cell lines with IC50 values of 1.47 and 1.73 microg/mL, respectively. Topics: Allantoin; Antineoplastic Agents, Phytogenic; Drug Screening Assays, Antitumor; Gallic Acid; Humans; K562 Cells; Lignans; Plant Stems; Polyalthia; Sitosterols; Stigmasterol	2013

Article

Year

(+)-rumphiin and polyalthurea, new compounds from the stems of Polyalthia rumphii.

Natural product communications, 2013, Volume: 8, Issue:10

Two new compounds, (+)-rumphiin (3) and polyalthurea (7), together with seven known ones, 3,4,5-trimethoxy benzoic acid (1), (-)-seselinone (2), cannabisin D (4), allantoin (5), oxostephanine (6) and a mixture of beta-sitosterol (8) and stigmasterol (9) were isolated from the stems of Polyalthia rumphii. The chemical structures of 3 and 7 were elucidated by the combination of spectroscopic data, and the absolute configuration of 3 at C-2 was determined by the matrix method to be R. All compounds were evaluated for their cytotoxicity on four human cancer cell lines, which demonstrated that 3 was a moderate bioactive lignan, and 6 showed significant anticancer activity against SPC-A-1 and BEL-7402 cell lines with IC50 values of 1.47 and 1.73 microg/mL, respectively.

Topics: Allantoin; Antineoplastic Agents, Phytogenic; Drug Screening Assays, Antitumor; Gallic Acid; Humans; K562 Cells; Lignans; Plant Stems; Polyalthia; Sitosterols; Stigmasterol

2013