cytarabine and zalcitabine

cytarabine has been researched along with zalcitabine in 24 studies

Research

Studies (24)

TimeframeStudies, this research(%)All Research%
pre-19903 (12.50)18.7374
1990's9 (37.50)18.2507
2000's7 (29.17)29.6817
2010's5 (20.83)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Corbett, TH; Court, BA; Kessel, D; Phadtare, S; Renis, HE; Zimlicka, J1
Alam, N; Hong, J; Im, KS; Jung, JH; Lee, CK; Li, F; Liu, Y; Wang, W1
Benz, RD; Contrera, JF; Kruhlak, NL; Matthews, EJ; Weaver, JL1
González-Díaz, H; Orallo, F; Quezada, E; Santana, L; Uriarte, E; Viña, D; Yáñez, M1
Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A1
Chen, M; Fang, H; Liu, Z; Shi, Q; Tong, W; Vijay, V1
Afshari, CA; Chen, Y; Dunn, RT; Hamadeh, HK; Kalanzi, J; Kalyanaraman, N; Morgan, RE; van Staden, CJ1
Chen, CH; Cheng, YC1
Brett, CM; Giacomini, KM; Hui, AC; Wu, X; Yuan, G1
Mancini, WR1
Barchi, JJ; Driscoll, JS; Kelley, JA; Marquez, VE; Mitsuya, H; Roth, JS; Shirasaka, T; Siddiqui, MA1
Chen, CH; Cheng, YC; Vazquez-Padua, M1
Chisaka, O; Matsubara, K; Nagahata, T; Tsurimoto, T; Ueda, K1
Fukushima, S; Kawaguchi, T; Mishima, M; Nakano, M; Ohmura, M1
Lin, TS; Mancini, WR1
Kim, B; Loeb, LA1
Oh-hara, T; Tsuruo, T; Yusa, K1
Cinatl, J; Doerr, HW; Driever, PH; Gröschel, B; Kabickova, H; Kornhuber, B; Kotchetkov, R; Schwabe, D1
Cheng, YC; Chou, KM; Kukhanova, M1
Knecht, W; Munch-Petersen, B; Piskur, J1
Agarwal, RP; Fernandez, M; Han, T; Sarkar, M1
Eklund, H; Mikkelsen, NE; Munch-Petersen, B1
Dalla Rosa, I; Dexheimer, TS; Gmeiner, WH; Huang, SY; Murai, J; Naumova, A; Pommier, Y1
Morin, B; Whelan, SP1

Other Studies

24 other study(ies) available for cytarabine and zalcitabine

ArticleYear
Unsaturated and carbocyclic nucleoside analogues: synthesis, antitumor, and antiviral activity.
    Journal of medicinal chemistry, 1991, Volume: 34, Issue:1

    Topics: Adenosine Deaminase; Animals; Antimetabolites, Antineoplastic; Antiviral Agents; Cell Line; Cell Survival; Drug Screening Assays, Antitumor; Friend murine leukemia virus; HIV-1; HIV-2; Humans; Indicators and Reagents; Leukemia L1210; Mice; Molecular Structure; Nucleosides; Rauscher Virus; Structure-Activity Relationship

1991
New saponins from the starfish Certonardoa semiregularis.
    Journal of natural products, 2002, Volume: 65, Issue:11

    Topics: Animals; Antineoplastic Agents; Antiviral Agents; Artemia; HeLa Cells; Humans; Korea; Molecular Structure; Nuclear Magnetic Resonance, Biomolecular; Saponins; Starfish; Stereoisomerism; Steroids

2002
Assessment of the health effects of chemicals in humans: II. Construction of an adverse effects database for QSAR modeling.
    Current drug discovery technologies, 2004, Volume: 1, Issue:4

    Topics: Adverse Drug Reaction Reporting Systems; Artificial Intelligence; Computers; Databases, Factual; Drug Prescriptions; Drug-Related Side Effects and Adverse Reactions; Endpoint Determination; Models, Molecular; Quantitative Structure-Activity Relationship; Software; United States; United States Food and Drug Administration

2004
Quantitative structure-activity relationship and complex network approach to monoamine oxidase A and B inhibitors.
    Journal of medicinal chemistry, 2008, Nov-13, Volume: 51, Issue:21

    Topics: Computational Biology; Drug Design; Humans; Isoenzymes; Molecular Structure; Monoamine Oxidase; Monoamine Oxidase Inhibitors; Quantitative Structure-Activity Relationship

2008
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
    Chemical research in toxicology, 2010, Volume: 23, Issue:1

    Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship

2010
FDA-approved drug labeling for the study of drug-induced liver injury.
    Drug discovery today, 2011, Volume: 16, Issue:15-16

    Topics: Animals; Benchmarking; Biomarkers, Pharmacological; Chemical and Drug Induced Liver Injury; Drug Design; Drug Labeling; Drug-Related Side Effects and Adverse Reactions; Humans; Pharmaceutical Preparations; Reproducibility of Results; United States; United States Food and Drug Administration

2011
A multifactorial approach to hepatobiliary transporter assessment enables improved therapeutic compound development.
    Toxicological sciences : an official journal of the Society of Toxicology, 2013, Volume: 136, Issue:1

    Topics: Animals; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Transport; Chemical and Drug Induced Liver Injury; Cluster Analysis; Drug-Related Side Effects and Adverse Reactions; Humans; Liver; Male; Multidrug Resistance-Associated Proteins; Pharmacokinetics; Rats; Rats, Sprague-Dawley; Recombinant Proteins; Risk Assessment; Risk Factors; Toxicity Tests

2013
The role of cytoplasmic deoxycytidine kinase in the mitochondrial effects of the anti-human immunodeficiency virus compound, 2',3'-dideoxycytidine.
    The Journal of biological chemistry, 1992, Feb-15, Volume: 267, Issue:5

    Topics: Cell Division; Cell Line; Cell Survival; Cytarabine; Cytoplasm; Deoxycytidine Kinase; DNA Replication; DNA, Mitochondrial; Drug Resistance; Humans; Kinetics; Mitochondria; Thymidine; Zalcitabine

1992
Sodium-dependent nucleoside transport in choroid plexus from rabbit. Evidence for a single transporter for purine and pyrimidine nucleosides.
    The Journal of biological chemistry, 1992, May-05, Volume: 267, Issue:13

    Topics: Adenosine Triphosphate; Animals; Carrier Proteins; Choroid Plexus; Cytarabine; Didanosine; Membrane Proteins; Nucleoside Transport Proteins; Purine Nucleosides; Pyrimidine Nucleosides; Rabbits; Sodium; Substrate Specificity; Zalcitabine; Zidovudine

1992
The role of deoxycytidine-metabolizing enzymes in the cytotoxicity induced by 3'-amino-2',3'-dideoxycytidine and cytosine arabinoside.
    Cancer chemotherapy and pharmacology, 1992, Volume: 30, Issue:2

    Topics: Animals; Antineoplastic Agents; Cell Count; Cell Division; Cytarabine; Cytidine Deaminase; Deoxycytidine; HeLa Cells; Humans; Leukemia L1210; Mice; Nucleoside Deaminases; Sensitivity and Specificity; Tumor Cells, Cultured; Zalcitabine

1992
Chemistry and anti-HIV properties of 2'-fluoro-2',3'-dideoxyarabinofuranosylpyrimidines.
    Journal of medicinal chemistry, 1992, Jun-12, Volume: 35, Issue:12

    Topics: Animals; Antiviral Agents; CD4-Positive T-Lymphocytes; Cell Line; Chemical Phenomena; Chemistry, Physical; Cytarabine; Cytidine Deaminase; Cytopathogenic Effect, Viral; Dose-Response Relationship, Drug; Drug Stability; HIV-1; Hydrogen-Ion Concentration; Macaca mulatta; Molecular Structure; Structure-Activity Relationship; Zalcitabine

1992
Effect of anti-human immunodeficiency virus nucleoside analogs on mitochondrial DNA and its implication for delayed toxicity.
    Molecular pharmacology, 1991, Volume: 39, Issue:5

    Topics: Antiviral Agents; Cell Line; Cytarabine; Didanosine; Dideoxynucleosides; DNA, Mitochondrial; HIV; Humans; Lymphocyte Activation; Nucleosides; Stavudine; T-Lymphocytes; Zalcitabine; Zidovudine

1991
An in vitro system for screening anti-hepatitis B virus drugs.
    Virology, 1989, Volume: 169, Issue:1

    Topics: Acyclovir; Adenine; Antiviral Agents; Blotting, Southern; Carcinoma, Hepatocellular; Cytarabine; Dideoxyadenosine; Dideoxynucleosides; DNA Replication; DNA, Viral; Hepatitis B virus; Humans; Interferons; Liver Neoplasms; Tumor Cells, Cultured; Vidarabine; Virus Replication; Zalcitabine; Zidovudine

1989
Enzymatic and chemical stability of 2',3'-dideoxy-2',3'-didehydropyrimidine nucleosides: potential anti-acquired immunodeficiency syndrome agents.
    Chemical & pharmaceutical bulletin, 1989, Volume: 37, Issue:7

    Topics: Acquired Immunodeficiency Syndrome; Animals; Antiviral Agents; Chemical Phenomena; Chemistry; Cytarabine; Dideoxynucleosides; Drug Stability; Humans; Mice; Stavudine; Zalcitabine

1989
Ribo- and deoxyribonucleoside effect on 3'-amino-2',3'-dideoxycytidine-induced cytotoxicity in cultured L1210 cells.
    Biochemical pharmacology, 1983, Aug-15, Volume: 32, Issue:16

    Topics: Animals; Antineoplastic Agents; Cell Survival; Cells, Cultured; Cytarabine; Deamination; Deoxycytidine; Deoxyribonucleosides; DNA, Neoplasm; Leukemia L1210; Ribonucleosides; Zalcitabine

1983
A screen in Escherichia coli for nucleoside analogs that target human immunodeficiency virus (HIV) reverse transcriptase: coexpression of HIV reverse transcriptase and herpes simplex virus thymidine kinase.
    Journal of virology, 1995, Volume: 69, Issue:10

    Topics: Antiviral Agents; Cloning, Molecular; Cytarabine; DNA Polymerase I; Drug Evaluation, Preclinical; Escherichia coli; Gene Expression; HIV; Kinetics; Phosphorylation; Recombinant Proteins; Reverse Transcriptase Inhibitors; RNA-Directed DNA Polymerase; Simplexvirus; Thymidine Kinase; Zalcitabine; Zidovudine

1995
Induction of resistance to 1-beta-D-arabinofuranosylcytosine in human H9 cell line by simian immunodeficiency virus.
    Biochemical and biophysical research communications, 1995, Jan-17, Volume: 206, Issue:2

    Topics: Cell Division; Cell Line; Cell Survival; Cytarabine; Cytidine Deaminase; Drug Resistance; Fluorouracil; Humans; Leukemia-Lymphoma, Adult T-Cell; Mercaptopurine; Simian Immunodeficiency Virus; Tetrahydrouridine; Tumor Cells, Cultured; Vidarabine; Zalcitabine; Zidovudine

1995
Azidothymidine resistance of H9 human T-cell lymphoma cells is associated with decreased sensitivity to antitumor agents and inhibition of apoptosis.
    International journal of molecular medicine, 1998, Volume: 2, Issue:6

    Topics: Anti-HIV Agents; Antimetabolites; Antineoplastic Agents; Apoptosis; Cytarabine; Drug Resistance, Neoplasm; Gene Expression Regulation, Neoplastic; Humans; Lymphoma, T-Cell; Tumor Cells, Cultured; Zalcitabine; Zidovudine

1998
A novel action of human apurinic/apyrimidinic endonuclease: excision of L-configuration deoxyribonucleoside analogs from the 3' termini of DNA.
    The Journal of biological chemistry, 2000, Oct-06, Volume: 275, Issue:40

    Topics: Anions; Antineoplastic Agents; Antiviral Agents; Blotting, Western; Carbon-Oxygen Lyases; Cations; Chromatography, Agarose; Chromatography, Ion Exchange; Cytarabine; Cytosine; Deoxycytidine; Deoxycytidine Monophosphate; Deoxyribonuclease IV (Phage T4-Induced); Dioxolanes; DNA; DNA-(Apurinic or Apyrimidinic Site) Lyase; Electrophoresis, Polyacrylamide Gel; Endonucleases; Humans; Oligonucleotides; Recombinant Proteins; Reverse Transcriptase Inhibitors; Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization; Stereoisomerism; Thionucleosides; Tumor Cells, Cultured; Zalcitabine

2000
Identification of residues involved in the specificity and regulation of the highly efficient multisubstrate deoxyribonucleoside kinase from Drosophila melanogaster.
    Journal of molecular biology, 2000, Aug-25, Volume: 301, Issue:4

    Topics: Animals; Cytarabine; Dideoxyadenosine; Directed Molecular Evolution; Drosophila melanogaster; Enzyme Activation; Feedback; Inhibitory Concentration 50; Kinetics; Mutation; Phosphorylation; Phosphotransferases (Alcohol Group Acceptor); Polymerase Chain Reaction; Substrate Specificity; Thymidine; Thymine Nucleotides; Zalcitabine; Zidovudine

2000
2', 3'-Dideoxycytidine represses thymidine kinases 1 and 2 expression in T-lymphoid cells.
    Life sciences, 2004, Jan-02, Volume: 74, Issue:7

    Topics: Anti-HIV Agents; Blotting, Western; Cells, Cultured; Cytarabine; DNA Primers; Down-Regulation; Drug Resistance, Multiple; Gene Expression Regulation, Enzymologic; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; T-Lymphocytes; Thymidine Kinase; Zalcitabine; Zidovudine

2004
Structural studies of nucleoside analog and feedback inhibitor binding to Drosophila melanogaster multisubstrate deoxyribonucleoside kinase.
    The FEBS journal, 2008, Volume: 275, Issue:9

    Topics: Adenosine Diphosphate; Animals; Antimetabolites; Bromodeoxyuridine; Cytarabine; Cytidine Triphosphate; Drosophila melanogaster; Drosophila Proteins; Feedback; Floxuridine; Guanosine Triphosphate; Hydrogen Bonding; Inhibitory Concentration 50; Kinetics; Models, Chemical; Models, Molecular; Phosphotransferases (Alcohol Group Acceptor); Protein Binding; Protein Structure, Secondary; Structure-Activity Relationship; Thymine Nucleotides; X-Ray Diffraction; Zalcitabine; Zidovudine

2008
TDP1 repairs nuclear and mitochondrial DNA damage induced by chain-terminating anticancer and antiviral nucleoside analogs.
    Nucleic acids research, 2013, Volume: 41, Issue:16

    Topics: Acyclovir; Animals; Anti-HIV Agents; Antimetabolites, Antineoplastic; Antiviral Agents; Cell Line; Cell Nucleus; Cells, Cultured; Chickens; Cytarabine; DNA Damage; DNA Repair; DNA, Mitochondrial; Gene Deletion; Mice; Phosphoric Diester Hydrolases; Zalcitabine; Zidovudine

2013
Sensitivity of the polymerase of vesicular stomatitis virus to 2' substitutions in the template and nucleotide triphosphate during initiation and elongation.
    The Journal of biological chemistry, 2014, Apr-04, Volume: 289, Issue:14

    Topics: Animals; Antimetabolites, Antineoplastic; Cytarabine; Promoter Regions, Genetic; RNA-Dependent RNA Polymerase; RNA, Viral; Sf9 Cells; Spodoptera; Transcription Elongation, Genetic; Transcription Initiation, Genetic; Vesiculovirus; Viral Proteins; Zalcitabine

2014