cytarabine has been researched along with uridine in 175 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 154 (88.00) | 18.7374 |
| 1990's | 10 (5.71) | 18.2507 |
| 2000's | 7 (4.00) | 29.6817 |
| 2010's | 3 (1.71) | 24.3611 |
| 2020's | 1 (0.57) | 2.80 |
| Authors | Studies |
|---|---|
| Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A | 1 |
| Guinan, M; Huang, N; Miller, GJ; Smith, M | 1 |
| Kaufmann, M; Mattern, J; Volm, M; Wayss, K | 1 |
| Bloch, A | 1 |
| Wentworth, DF; Wolfenden, R | 1 |
| Ng, SK; Rogers, J; Sanwal, BD | 1 |
| Honjo, T; Mizuno, D; Natori, S; Shimizu, A; Tsuda, M | 1 |
| Hatanaka, M; Takano, T | 1 |
| Furner, RL; Mellett, LB | 1 |
| Brockman, RW; Nelson, JA; Rose, LM; Schabel, FM; Shaddix, SC; Williams, M | 1 |
| Jackson, RC; Weber, G; Williams, JC | 1 |
| Attallah, AM; Houck, JC | 1 |
| Heichal, O; Ish-Shalom, D; Koren, R; Stein, WD | 1 |
| De Clercq, E; Descamps, J; Kulikowski, T; Shugar, D; Zawadzki, Z | 1 |
| Grindey, GB; Mihich, E | 1 |
| Burchenal, JH; Currie, VE; Krakoff, IH; Mackey, RW; Tan, CT; Wong, PP; Young, CW | 1 |
| Jakobs, ES; Lauzon, GJ; Paterson, AR; Weinstein, WM | 1 |
| Mak, TW; Wan, CW | 1 |
| Ikeda, K; Mizuno, Y; Takeda, T | 1 |
| Gordon, CS; Krakoff, IH; Kreis, W; Woodcock, TM | 1 |
| Hession, C; Kreis, W; Scully, K; Soricelli, A | 1 |
| Bibi, O; Koren, R; Shohami, E; Stein, WD | 1 |
| Lauzon, GJ; Mills-Yamamoto, C; Paterson, AR | 1 |
| Bibi, O; Cabantchik, ZI; Heichal, O; Katz, J | 1 |
| Bodey, GP; Freireich, EJ; Ho, DH; Loo, TL | 1 |
| Rozengurt, E; Stein, WD; Wigglesworth, NM | 1 |
| McLeod, R; Remington, JS | 1 |
| Bouchard, M; Bousser, J; Diaz-Mayo, C; Facquet-Danis, J; Percie-du-Sert, M; Zittoun, R | 1 |
| Baguley, BC; Falkenhaug, EM | 1 |
| Furner, RL; Herren, TC; Mellett, LB | 1 |
| Breen, GA; de Vellis, J | 1 |
| Håkansson, L | 1 |
| Hoshi, A; Ichino, M; Kanai, T; Kuretani, K; Yoshida, M | 1 |
| Fischer, GA; Theiss, JC | 1 |
| Aran, JM; Plagemann, PG | 1 |
| Senderoff, RI; Smith, DR; Sokoloski, TD; Weber, PA | 1 |
| Mattern, J; Pommerenke, EW; Traugott, U; Volm, M | 1 |
| Cao, S; Wu, S; Xue, Y; Zhen, Y | 1 |
| Mejer, J | 1 |
| Hayashi, N; Matuzaki, T; Murase, T; Nakada, H; Nakamura, T; Osada, K; Takahashi, I; Takeuchi, M; Ueki, Y; Yorimitsu, S | 1 |
| Chomel, B; Fourel, I; Fox, JJ; Hantz, O; Jacquet, C; Trepo, C; Watanabe, KA | 1 |
| Moriconi, WJ; Slavik, M; Taylor, S | 1 |
| Lycke, E; Svennerholm, B; Ziegler, R | 1 |
| Arnon, R; Hurwitz, E; Kashi, R; Sela, M; Wilchek, M | 1 |
| Lasorella, A; Riccardi, A; Riccardi, R; Servidei, T | 1 |
| Khoobehi, B; Niesman, MR; Oncel, M; Peyman, GA | 1 |
| Capizzi, RL; Chandrasekaran, B; Dimling, J; Kute, TE; Morgan, T | 1 |
| Hassan, FM; Pesce, AJ; Pruemer, JM; Warner, A; Wermeling, JR | 1 |
| Engle, KK; Higuchi, T; Liversidge, GG; Nishihata, T | 1 |
| Belt, JA; Noel, LD | 1 |
| Fox, JJ; Harada, K; Matulic-Adamic, J; Price, RW; Schinazi, RF; Watanabe, KA | 1 |
| Agostino, FC; Bernabei, PA; Bezzini, R; Leoni, F; Rossi Ferrini, P; Saccardi, R | 1 |
| Allen, S; Budman, DR; Chan, K; Deere, M; Freeman, J; Henderson, V; Kreis, W; Lichtman, S; Schulman, P; Weiselberg, L | 1 |
| Muus, P; Punt, K; Roelofs, JM; van Prooijen, HC | 1 |
| Avramis, VI; Powell, W | 1 |
| Driscoll, JS; Kelley, JA; Marquez, VE; McCormack, JJ; Roth, JS | 1 |
| Colly, LP; Edelbroek, PM; Honders, W; vd Hoorn, F; Willemze, R | 1 |
| Andrejczuk, A; Holland, JF; Ohnuma, T; Perlow, L; Shafir, M; Strauchen, J | 1 |
| Capizzi, RL; Cheng, EH; Cheng, YC; Kute, T; Yang, JL | 1 |
| Seidel, HJ | 1 |
| Goerttler, K; Kaufmann, M; Mattern, J; Volm, M; Wayss, K | 1 |
| Mattern, J; Volm, M; Wayss, K | 2 |
| Jones, RE; Moscona, AA | 1 |
| Scholtissek, C | 1 |
| Chu, MY; Fischer, GA; Momparler, RL | 1 |
| Kemper, B; Rich, A | 1 |
| Pennington, TH | 1 |
| Cremer, NE; Lennette, EH; Oshiro, LS; Teitz, Y | 1 |
| Topper, YJ; Vonderhaar, BK | 1 |
| Chun, LL; Patterson, PH | 1 |
| Calabresi, P; Creasey, WA; Markiw, ME; Papac, RJ; Welch, AD | 1 |
| Bitter-Suermann, D; Clauss, I; Falke, D | 1 |
| Lee, SH | 1 |
| Falke, D | 1 |
| Guentzel, MJ; Rapp, F | 1 |
| Ernberg, I; Gergely, L; Klein, G | 1 |
| Bader, JP | 1 |
| Anderson, CW; Gesteland, RF | 1 |
| Prévost, JM; Thiry, L; Toussaint, C; Vereerstraeten, P | 1 |
| Rideau, C; Smulson, ME | 1 |
| Warnaar, SO; Weinberg, RA; Winocour, E | 1 |
| Rouhandeh, H; Yau, TM | 1 |
| Notkins, AL; Yamazaki, S | 1 |
| Sokol, F; Tan, KB | 1 |
| Kit, S; May, JT; Somers, KD | 1 |
| Brandner, G; Mueller, N | 1 |
| Benyesh-Melnick, M; Biswal, N; Murray, BK | 1 |
| Sato, K; Shiomi, T | 1 |
| Peterkofsky, B; Tomkins, GM | 1 |
| Moscona, AA; Sarkar, PK | 1 |
| Loehr, EV; Roberts, D | 1 |
| Ho, DH | 3 |
| Engberg, J; Frederiksen, S; Hellung-Larsen, P; Pedersen, IR | 1 |
| Dixon, RL; Lee, IP | 1 |
| Weintraub, H | 1 |
| Hunt, DE; Narkates, AJ | 1 |
| Berger, AE; Kuentzel, SL; Neil, GL | 1 |
| Cox, RP; Malathi, VG; Meyers, R; Silber, R | 1 |
| Nagyvary, J; Pollard, DR | 1 |
| Kelley, DE; Perry, RP | 1 |
| Byfield, JE; Karlsson, U | 1 |
| Atherton, KT; Darby, G | 1 |
| Chan, BW | 1 |
| Manak, RC; Moxley, TE; Neil, GL | 1 |
| Bhuyan, BK; Buskirk, HH; Kuentzel, SL; Manak, RC; Moxley, TE; Neil, GL | 1 |
| Hanka, LJ; Kuentzel, SL; Neil, GL | 1 |
| Werner, GH | 1 |
| Cass, CE; Paterson, AR | 1 |
| Bodo, G; Horak, I; Jungwirth, C; Lindner, J; Schultze, B | 1 |
| Mizel, SB; Wilson, L | 1 |
| Campbell, GL; Holtzer, H; Weintraub, H | 1 |
| Penman, S; Price, R | 1 |
| Cummins, EP; Rivera, EM | 1 |
| Oliver, JM | 1 |
| Farrow, MG; Van Dyke, K | 1 |
| Chu, MY | 1 |
| Brown, RK; Hudson, RA; Lieu, TS; White, BC | 1 |
| Cline, MJ | 1 |
| Cline, MJ; Rosenbaum, E | 1 |
| Guganig, ME; Nakai, GS | 1 |
| Inagaki, A; Nakamura, T; Wakisaka, G | 1 |
| Cowell, LA; Weston, JA | 1 |
| Bather, R; Leonard, A | 1 |
| Grindey, GB; Kline, I; Saslaw, LD; Waravdekar, VS | 1 |
| Grindey, GB; Saslaw, LD; Waravdekar, VS | 1 |
| Granoff, A; Kucera, LS | 1 |
| Bader, JP; Nakata, Y | 1 |
| Fischinger, PJ; Hirschman, SZ; O'Connor, TE; Zaccari, JJ | 1 |
| Bather, R; Buck, BM | 1 |
| Baserga, R; Estensen, RD | 1 |
| Bases, RE; King, AS | 1 |
| Flickinger, RA; Miyagi, M; Moser, CR; Rollins, E | 1 |
| Agarwal, RP; Lopez, JA | 1 |
| Campbell, J; Li, ZR; Rustum, YM | 1 |
| Cadman, E; Grant, S | 1 |
| Hsiung, GD; Mayo, DR | 1 |
| Benjamin, RS; Bodey, GP; Brown, NS; Carter, CJ; Freireich, EJ; Hester, J; Ho, DH; McCredie, K | 1 |
| Kanner, N; Koren, R; Shohami, E | 1 |
| Mathews, CK; North, TW | 1 |
| Chou, TC; Feinberg, A; Fox, JJ; Philips, FS; Su, TL; Vidal, PM; Watanabe, KA | 1 |
| Cheng, YC; Lin, JC; Pagano, JS; Smith, MC | 1 |
| Kodama, K; Kuninaka, A; Morozumi, M; Sato, T; Yoshino, H | 1 |
| Evans, WE; Sinkule, JA | 1 |
| Killmann, SA; Nielsen, HR | 1 |
| Bloch, A; Craig, RW; Frankfurt, OS; Sakagami, H; Takeda, K | 1 |
| Nahmias, AJ; Peters, J; Schinazi, RF; Sokol, MK | 1 |
| Cortese, M; Higuchi, T; Liversidge, GG; Nishihata, T; Shaffer, R | 1 |
| Bjornsson, T; Capizzi, RL; Cheng, E; Cheng, YC; Sahasrabudhe, D; Tan, RS; Yang, JL | 1 |
| Fox, JJ; Last-Barney, K; Merluzzi, VJ | 1 |
| Lauzon, GJ; Paterson, AR; Yang, S | 1 |
| Chabner, B; Glaubiger, DL; Poplack, DG; Riccardi, R; Wood, J | 1 |
| Barlogie, B; Chubb, S; Plunkett, W | 1 |
| Marquardt, H; Westendorf, J | 1 |
| Au, JL; Danhauser, L; Luccioni, C; Rustum, YM | 1 |
| Hirobe, M; Makino, Y; Matsubara, Y; Watanabe, K | 1 |
| Braun, TJ; Burchenal, JH; Chou, TC; Fox, JJ; Philips, FS; Schmid, FA; Su, TL; Watanabe, KA | 1 |
| Fox, JJ; Philips, FS; Price, RW; Rottenberg, DA; Saito, Y; Su, TL; Watanabe, KA | 1 |
| Drenthe-Schonk, A; Haanen, C; Linssen, P; Wessels, H | 1 |
| Breithaupt, H; Schick, J | 1 |
| Barlogie, B; Keating, M; Latreille, J; McCredie, K; Plunkett, W; Raber, M | 1 |
| Inui, N; Sato, S; Takizawa, H | 1 |
| Wiley, JS | 1 |
| Baldwin, SA; Beaumont, N; Boumah, CE; Cass, CE; Coe, I; Davies, A; Griffiths, M; Kwong, FY; Sundaram, M; Yao, SY; Young, JD | 1 |
| Hohl, RJ; Jung, KY; Wiemer, AJ; Wiemer, DF | 1 |
| Kodama, T; Matsuda, A; Nomura, M; Shuto, S | 1 |
| Cass, CE; Clarke, ML; Gourdeau, H; Jolivet, J; Lafrenière, RG; Lee, N; Mackey, JR; Mowles, D; Ouellet, F; Richard, A; Selner, M; Young, JD | 1 |
| Chen, X; Wiemer, DF | 1 |
| Cass, CE; Clarke, ML; Damaraju, VL; Lang, T; Mowles, D; Smith, KM; Tackaberry, T; Tomkinson, B; Young, JD; Zhang, J | 1 |
| Fujimoto, S; Hotta, A; Koma, M; Nagai, K; Nagasawa, K | 1 |
| Choi, WJ; Jeong, LS; Kim, YM; Lee, H; Lee, SK; Tosh, DK | 1 |
| Agrofoglio, LA; Mieczkowski, A | 1 |
| Alzeer, J; Glasauer, SMK; Luedtke, NW; Messikommer, A; Paulisch, MH; Triemer, T | 1 |
4 review(s) available for cytarabine and uridine
| Article | Year |
|---|---|
The structure of nucleosides in relation to their biological and and biochemical activity: a summary.
Topics: 3-Deazauridine; Adenine; Adenosine; Anti-Bacterial Agents; Azacitidine; Cytarabine; Idoxuridine; Isopentenyladenosine; Nucleosides; Pseudouridine; Puromycin; Structure-Activity Relationship; Tubercidin; Uridine | 1975 |
Multiple basis of combination chemotherapy.
Topics: Animals; Antineoplastic Agents; Cyclophosphamide; Cytarabine; Daunorubicin; Drug Antagonism; Drug Interactions; Drug Synergism; Drug Therapy, Combination; Humans; Leucovorin; Mercaptopurine; Methotrexate; Neoplasms; Neoplasms, Experimental; Uridine | 1977 |
Determinants of response to antimetabolites and their modulation by normal purine and pyrimidine metabolites.
Topics: Animals; Antimetabolites, Antineoplastic; Cytarabine; DNA, Neoplasm; Fluorodeoxyuridylate; Fluorouracil; Humans; Leukemia L1210; Neoplasms; Neoplasms, Experimental; Thymidine; Thymidylate Synthase; Uridine | 1981 |
Potential and perspectives of cyclonucleosides.
Topics: Antineoplastic Agents; Antiviral Agents; Cytarabine; Nucleosides; Uridine | 2010 |
1 trial(s) available for cytarabine and uridine
| Article | Year |
|---|---|
Phase I evaluation of tetrahydrouridine combined with cytosine arabinoside.
Topics: Bone Marrow; Clinical Trials as Topic; Cytarabine; Drug Evaluation; Drug Synergism; Drug Therapy, Combination; Humans; Leukemia; Lymphoma; Middle Aged; Neoplasms; Nucleoside Deaminases; Pyrimidine Nucleosides; Tetrahydrouridine; Uridine | 1979 |
170 other study(ies) available for cytarabine and uridine
| Article | Year |
|---|---|
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship | 2010 |
Design, chemical synthesis and antiviral evaluation of 2'-deoxy-2'-fluoro-2'-C-methyl-4'-thionucleosides.
Topics: Antiviral Agents; Dose-Response Relationship, Drug; Drug Design; Hepacivirus; Microbial Sensitivity Tests; Molecular Structure; Structure-Activity Relationship; Thionucleosides; Virus Replication | 2022 |
[Sensitivity tests of malignant tumours against cytostatic agents in vitro and in vivo/studies on the mouse sarcoma 180 (author's transl)].
Topics: Animals; Antineoplastic Agents; Biological Transport; Bleomycin; Cell Membrane Permeability; Cells, Cultured; Cytarabine; Dactinomycin; Daunorubicin; Doxorubicin; Fluorouracil; Methotrexate; Mice; Mice, Inbred Strains; Podophyllin; Sarcoma 180; Uridine | 1975 |
On the interaction of 3,4,5,6-tetrahydrouridine with human liver cytidine deaminase.
Topics: Azacitidine; Binding Sites; Cytarabine; Cytidine Deaminase; Humans; Kinetics; Liver; Nucleoside Deaminases; Protein Binding; Tetrahydrouridine; Uridine | 1975 |
Alterations in differentiation and pyrimidine pathway enzymes in 5-azacytidine resistant variants of a myoblast line.
Topics: Adenosine; Animals; Aspartate Carbamoyltransferase; Azacitidine; Azaguanine; Bromodeoxyuridine; Cell Differentiation; Cell Fusion; Cell Line; Cytarabine; Cytidine Deaminase; Drug Resistance; Genetic Variation; Muscles; Nucleoside Deaminases; Orotate Phosphoribosyltransferase; Orotidine-5'-Phosphate Decarboxylase; Ouabain; Phosphotransferases; Rats; Theophylline; Thymidine; Uridine; Uridine Kinase | 1977 |
Induced synthesis of immunoglobulin messenger RNA accompanies induction of immunoglobulin production in cultured mouse spleen cells.
Topics: Animals; Cycloheximide; Cytarabine; Dactinomycin; DNA; Escherichia coli; Globins; Hydroxyurea; Immunoglobulin kappa-Chains; Immunoglobulin Light Chains; Lipopolysaccharides; Male; Mice; RNA, Messenger; Spleen; Uridine | 1978 |
Fate of viral RNA of murine leukemia virus after infection.
Topics: Animals; Cell Line; Cell Nucleus; Cell Transformation, Neoplastic; Centrifugation, Density Gradient; Cytarabine; Cytoplasm; DNA, Neoplasm; DNA, Viral; Fibroblasts; Leukemia Virus, Murine; Mice; Mice, Inbred BALB C; Nucleic Acid Denaturation; Nucleic Acid Hybridization; Rauscher Virus; RNA, Neoplasm; RNA, Viral; Tritium; Uridine | 1975 |
Kinase and deaminase activity in a variety of subcutaneous mouse tumors.
Topics: Adenocarcinoma; Aminohydrolases; Animals; Cell Line; Chick Embryo; Cytarabine; Freezing; Glioma; Lung Neoplasms; Mammary Neoplasms, Experimental; Melanoma; Mice; Mice, Inbred AKR; Mice, Inbred C3H; Mice, Inbred C57BL; Mice, Inbred DBA; Neoplasms, Experimental; Osteosarcoma; Phosphotransferases; Pyrimidine Nucleotides; Sarcoma 180; Tetrahydrouridine; Uridine | 1975 |
The mechanism of action of 3-deazauridine in tumor cells sensitive and resistant to arabinosylcytosine.
Topics: 3-Deazauridine; Adenocarcinoma; Animals; Cell Line; Cytarabine; Deoxycytidine; Deoxyribonucleotides; DNA, Neoplasm; Drug Resistance; Leukemia L1210; Liver; Mice; Neoplasms, Experimental; Orotic Acid; Phosphotransferases; Pyrimidine Nucleotides; Ribonucleotide Reductases; Ribonucleotides; RNA, Neoplasm; Uracil Nucleotides; Uridine | 1975 |
Enzyme pattern-directed chemotherapy: synergistic interaction of 3-deazauridine with D-galactosamine.
Topics: 3-Deazauridine; Carcinoma, Hepatocellular; Cell Line; Cytarabine; Drug Combinations; Drug Synergism; Galactosamine; Half-Life; Liver Neoplasms; Uracil Nucleotides; Uridine | 1976 |
Tentative mechanism of lymphocyte chalone action.
Topics: Animals; Bucladesine; Cattle; Cycloheximide; Cytarabine; DNA; Growth Inhibitors; In Vitro Techniques; Lectins; Leucine; Lymphocyte Activation; Lymphocytes; Spleen; Theophylline; Thymidine; Time Factors; Uridine | 1977 |
The kinetic dissection of transport from metabolic trapping during substrate uptake by intact cells. Uridine uptake by quiescent and serum-activated Nil 8 hamster cells and their murine sarcoma virus-transformed counterparts.
Topics: Animals; Biological Transport, Active; Cell Line; Cell Transformation, Viral; Cricetinae; Cytarabine; Gammaretrovirus; Kinetics; Mathematics; Sarcoma Viruses, Murine; Uridine | 1979 |
Synthesis and antiviral activities of arabinofuranosyl-5-ethylpyrimidine nucleosides. Selective antiherpes activity of 1-(beta-D-arabinofuranosyl)-5-ethyluracil.
Topics: Antiviral Agents; Arabinofuranosyluracil; Circular Dichroism; Cytarabine; Cytopathogenic Effect, Viral; Deamination; Magnetic Resonance Spectroscopy; Simplexvirus; Uridine; Vaccinia virus; Vesicular stomatitis Indiana virus | 1979 |
Drug sequence-dependent toxicity and small bowel mucosal injury in mice treated with low doses of 3-deazauridine and 1-beta-D-arabinofuranosylcytosine.
Topics: 3-Deazauridine; Animals; Cytarabine; Female; Intestinal Mucosa; Intestine, Small; Male; Mice; Thioinosine; Time Factors; Uridine | 1979 |
Effect of tetrahydrouridine on the action of 1-beta-D-arabinofuranosylcytosine in synchronized cultures of normal rat kidney cells.
Topics: Animals; Cell Cycle; Cell Survival; Cells, Cultured; Cytarabine; Cytidine Deaminase; DNA; Drug Synergism; Interphase; Kidney; Rats; Tetrahydrouridine; Time Factors; Uridine | 1979 |
Syntheses of 1-beta-D-arabinofuranosyl-5-hydroxymethyl-N4-alkylcytosine.
Topics: Cytarabine; Indicators and Reagents; Methods; Uridine | 1979 |
Tetrahydrouridine: Physiologic disposition and effect upon deamination of cytosine arabinoside in man.
Topics: Administration, Oral; Biological Availability; Cytarabine; Cytidine Deaminase; Deamination; Dose-Response Relationship, Drug; Drug Therapy, Combination; Half-Life; Humans; Injections, Intravenous; Neoplasms; Tetrahydrouridine; Uridine | 1977 |
Combinations of tetrahydrouridine and cytosine arabinoside in mouse tumors.
Topics: Adenocarcinoma; Animals; Cytarabine; Cytidine Deaminase; Deamination; Drug Evaluation; Drug Therapy, Combination; Female; Lung Neoplasms; Mice; Neoplasms, Experimental; Phosphotransferases; Sarcoma, Experimental; Tetrahydrouridine; Tritium; Uridine | 1977 |
Uridine transport properties of mammalian cell membranes are not directly involved with growth control or oncogenesis.
Topics: Biological Transport, Active; Cell Division; Cell Line; Cell Membrane; Cell Transformation, Neoplastic; Cell Transformation, Viral; Cytarabine; Kinetics; Membrane Proteins; Uridine | 1978 |
Toxicity of combinations of arabinosylcytosine and 3-deazauridine toward neoplastic cells in culture.
Topics: 3-Deazauridine; Antineoplastic Agents; Cytarabine; Drug Resistance; Drug Synergism; HeLa Cells; Uridine; Uridine Kinase | 1978 |
Nucleoside transport in mammalian cell membranes. III. Kinetic and chemical modification studies of cytosine-arabinoside and uridine transport in hamster cells in culture.
Topics: Affinity Labels; Biological Transport, Active; Cell Line; Cytarabine; Ethylmaleimide; Kinetics; Phenylmercury Compounds; Thioinosine; Uridine | 1978 |
Pharmacological and clinical studies of some nucleoside analogs.
Topics: Allopurinol; Cytarabine; Guanosine; Humans; Leukemia, Myeloid, Acute; Mercaptopurine; Nucleosides; Uridine | 1975 |
Uptake of nucleosides in density-inhibited cultures of 3T3 cells.
Topics: Biological Transport; Blood; Cell Line; Contact Inhibition; Culture Media; Cytarabine; Kinetics; Uridine | 1977 |
A new method for evaluation of intracellular inhibition of multiplication or killing by mononuclear phagocytes.
Topics: Animals; Cytarabine; Female; Mice; Phagocytes; Toxoplasma; Toxoplasmosis, Animal; Uridine | 1977 |
[In vitro study of sensitivity of leukemic cells to cytotoxic drugs (anticytogram)].
Topics: Acute Disease; Adolescent; Adult; Aged; Antineoplastic Agents; Asparaginase; Carbon Radioisotopes; Cells, Cultured; Cyclophosphamide; Cytarabine; Daunorubicin; Depression, Chemical; Humans; In Vitro Techniques; Leukemia; Leukemia, Lymphoid; Mercaptopurine; Middle Aged; Monomethylhydrazine; Prednisolone; Remission, Spontaneous; Thymidine; Tritium; Uridine; Vincristine | 1975 |
Plasma half-life of cytosine arabinoside in patients with leukaemia--the effect of uridine.
Topics: Administration, Oral; Aminohydrolases; Animals; Cell Count; Cytarabine; Deoxycytidine; DNA, Neoplasm; Dose-Response Relationship, Drug; Half-Life; Humans; Leukemia L1210; Leukemia, Myeloid; Leukocytes; Mice; Uridine | 1975 |
Influence of tetrahydrouridine on the phosphorylation of 1-beta-D-arabinofuranosyl-cytosine (ara-C) by enzymes from solid tumors in vitro.
Topics: Adenocarcinoma; Animals; Bone Neoplasms; Cytarabine; Cytidine Deaminase; Deoxycytidine; Female; In Vitro Techniques; Kinetics; L Cells; Liver; Lung Neoplasms; Male; Mice; Neoplasm Transplantation; Neoplasms, Experimental; Osteosarcoma; Phosphorus; Phosphotransferases; Sarcoma 180; Spleen; Tetrahydrouridine; Uridine | 1975 |
Regulation of glycerol phosphate dehydrogenase by hydrocortisone in rat brain explants.
Topics: Amanitins; Animals; Brain; Brain Stem; Cerebral Cortex; Cycloheximide; Cytarabine; Dactinomycin; Deoxyadenosines; DNA; Dose-Response Relationship, Drug; Enzyme Induction; Glycerolphosphate Dehydrogenase; Hydrocortisone; Leucine; Mesencephalon; Nerve Tissue Proteins; Organ Culture Techniques; Puromycin; Rats; RNA; Tritium; Uridine | 1975 |
Effect of cytostatic drugs on nucleic acid synthesis in mouse thymocytes and chick embryo cells.
Topics: Animals; Antineoplastic Agents; Cells, Cultured; Chick Embryo; Cytarabine; Dactinomycin; Deoxyadenosines; Deoxyuridine; DNA; Fluorouracil; Melphalan; Methotrexate; Mice; Mice, Inbred Strains; Thymidine; Thymus Gland; Triaziquone; Tritium; Uridine; Vinblastine | 1975 |
Action of 5-fluorocyclocytidine on cultured L-5178Y cells.
Topics: Animals; Cell Line; Cytarabine; Deoxyribonucleosides; DNA, Neoplasm; Leucine; Leukemia, Experimental; Neoplasm Proteins; RNA, Neoplasm; Thymidine; Uridine | 1975 |
Inhibition of intracellular pyrimidine ribonucleotide reduction by deoxycytidine, arabinosylcytosine and hydroxyurea.
Topics: Cell Line; Cytarabine; Deoxycytidine; Hydroxyurea; Oxidation-Reduction; Pyrimidine Nucleotides; Uridine | 1976 |
Nucleoside transport-deficient mutants of PK-15 pig kidney cell line.
Topics: Animals; Biological Transport; Carrier Proteins; Cell Division; Cell Line; Clone Cells; Cytarabine; DNA; Escherichia coli; Flow Cytometry; Floxuridine; Hypoxanthine; Hypoxanthines; Kidney; Kinetics; Membrane Proteins; Methotrexate; Mutation; Nucleoside Transport Proteins; Nucleosides; Plasmids; Recombinant Proteins; Swine; Thymidine; Transfection; Tubercidin; Uridine | 1992 |
Evaluation of antiproliferative agents using a cell-culture model.
Topics: Animals; Bleomycin; Cell Count; Cell Division; Cells, Cultured; Colorimetry; Cricetinae; Cytarabine; Drug Evaluation, Preclinical; Floxuridine; Fluorouracil; Tetrazolium Salts; Thiazoles; Time Factors; Uridine | 1990 |
[Reversal of multidrug resistance with (R)-verapamil in vitro and in vivo].
Topics: Animals; Antineoplastic Agents; Cytarabine; Doxorubicin; Drug Resistance; Female; Leukemia L1210; Mice; Stereoisomerism; Thymidine; Tumor Cells, Cultured; Uridine; Verapamil | 1991 |
Green tea extract inhibits nucleoside transport and potentiates the antitumor effect of antimetabolites.
Topics: Animals; Antineoplastic Agents, Phytogenic; Cytarabine; Drug Synergism; Female; Humans; Leukemia L1210; Leukemia P388; Male; Methotrexate; Mice; Mice, Inbred DBA; Plant Extracts; Tea; Thymidine; Tumor Cells, Cultured; Tumor Stem Cell Assay; Uridine | 1991 |
The impact of selected nucleosides on the cytotoxicity of Ara-C in HL60 cells.
Topics: Cell Line; Cell Survival; Cytarabine; Cytidine; Deoxyadenosines; Deoxycytidine; Deoxyguanosine; Drug Interactions; Humans; Kinetics; Leukemia, Promyelocytic, Acute; Nucleosides; Tetrahydrouridine; Uridine | 1991 |
Increased accumulation of cytosine arabinoside in human leukemic cells and enhancement of its cell-killing activity by uridine.
Topics: Cell Survival; Cytarabine; Drug Synergism; Humans; Leukemia; Phosphorylation; Tumor Cells, Cultured; Uridine | 1990 |
Inhibitory effects of 2'-fluorinated arabinosyl-pyrimidine nucleosides on woodchuck hepatitis virus replication in chronically infected woodchucks.
Topics: Administration, Oral; Animals; Antiviral Agents; Arabinofuranosyluracil; Chronic Disease; Cytarabine; Hepadnaviridae; Hepatitis, Viral, Animal; Uridine; Virus Replication | 1990 |
3-Deazauridine (NSC 126849): an interesting modulator of biochemical response.
Topics: 3-Deazauridine; Acute Disease; Animals; Antineoplastic Agents; Azacitidine; Cytarabine; Decitabine; Drug Evaluation; Drug Synergism; Galactosamine; Humans; Kinetics; Leukemia; Neoplasms; Thymidine; Uridine | 1986 |
Herpes simplex virus infection of the rat sensory neuron. Effects of interferon on cultured cells.
Topics: Animals; Cells, Cultured; Cytarabine; Floxuridine; Interferon Type I; Neurons; Rats; Simplexvirus; Uridine; Virus Replication | 1989 |
The covalent linking of two nucleotide analogues to antibodies.
Topics: Animals; Antibodies; Cytarabine; Dextrans; Dosage Forms; Leukemia, Experimental; Mice; Uridine | 1985 |
High-performance liquid chromatographic assay for cytosine arabinoside and uracil arabinoside in cerebrospinal fluid and plasma.
Topics: Arabinofuranosyluracil; Chromatography, High Pressure Liquid; Cytarabine; Humans; Leukemia; Spectrophotometry, Ultraviolet; Uridine | 1989 |
Hyperthermia and temperature-sensitive liposomes: selective delivery of drugs into the eye.
Topics: Animals; Aqueous Humor; Cytarabine; Drug Carriers; Eye; Hot Temperature; Hyperthermia, Induced; Liposomes; Microwaves; Rabbits; Uridine; Vitreous Body | 1989 |
Modulation of the metabolism and pharmacokinetics of 1-beta-D-arabinofuranosylcytosine by 1-beta-D-arabinofuranosyluracil in leukemic mice.
Topics: Animals; Arabinofuranosyluracil; Cytarabine; Cytidine Deaminase; Kidney; Kinetics; Leukemia L5178; Leukemia, Experimental; Liver; Male; Mice; Mice, Inbred Strains; Uridine | 1989 |
Liquid-chromatographic monitoring of cytosine arabinoside and its metabolite, uracil arabinoside, in serum.
Topics: Aged; Arabinofuranosyluracil; Chromatography, High Pressure Liquid; Cytarabine; Female; Humans; Leukemia, Myeloid, Acute; Male; Spectrophotometry, Ultraviolet; Uridine | 1989 |
Enhanced serum concentrations of Ara-C using suppositories containing tetrahydrouridine as a deamination inhibitor of Ara-C.
Topics: Animals; Arabinofuranosyluracil; Biological Availability; Cytarabine; Deamination; Dogs; Kinetics; Salicylates; Salicylic Acid; Suppositories; Tetrahydrouridine; Uridine | 1986 |
Isolation and characterization of a mutant of L1210 murine leukemia deficient in nitrobenzylthioinosine-insensitive nucleoside transport.
Topics: Animals; Biological Transport; Carrier Proteins; Cytarabine; Floxuridine; Inosine; Leukemia L1210; Membrane Proteins; Mice; Mutation; Nucleoside Transport Proteins; Nucleosides; Thioinosine; Thymidine; Tubercidin; Tumor Cells, Cultured; Uridine | 1988 |
Nucleosides. 139. Synthesis and anticytomegalovirus and antiherpes simplex virus activity of 5'-modified analogues of 2'-fluoroarabinosylpyrimidine nucleosides.
Topics: Animals; Antiviral Agents; Arabinofuranosyluracil; Cytarabine; Cytomegalovirus; Drug Evaluation, Preclinical; Fluorine; Indicators and Reagents; Magnetic Resonance Spectroscopy; Simplexvirus; Structure-Activity Relationship; Uridine; Vero Cells | 1987 |
In vitro short-term sensitivity test for the prediction of response to chemotherapy in acute non-lymphocytic leukemia.
Topics: Acute Disease; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Cells, Cultured; Cytarabine; Daunorubicin; Drug Screening Assays, Antitumor; Female; Humans; Leukemia; Male; Middle Aged; Time Factors; Uridine | 1988 |
Effect of tetrahydrouridine on the clinical pharmacology of 1-beta-D-arabinofuranosylcytosine when both drugs are coinfused over three hours.
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Bone Marrow; Cytarabine; Deamination; Female; Half-Life; Humans; Male; Middle Aged; Tetrahydrouridine; Uridine | 1988 |
Does the metabolite uracil arabinoside inhibit cytosine arabinoside (Ara-C) penetration into the cerebrospinal fluid during high-dose Ara-C therapy?
Topics: Adult; Arabinofuranosyluracil; Biological Transport; Blood-Brain Barrier; Cytarabine; Half-Life; Humans; Kinetics; Leukemia, Myeloid, Acute; Male; Uridine | 1986 |
Pharmacology of combination chemotherapy of cytosine arabinoside (ara-C) and uracil arabinoside (ara-U) or tetrahydrouridine (THU) against murine leukemia L1210/0 in tumor-bearing mice.
Topics: Animals; Antineoplastic Combined Chemotherapy Protocols; Arabinofuranosyluracil; Cytarabine; Deamination; Leukemia L1210; Male; Mice; Tetrahydrouridine; Time Factors; Uridine | 1987 |
Furanose-pyranose isomerization of reduced pyrimidine and cyclic urea ribosides.
Topics: Cytarabine; Cytidine Deaminase; Gas Chromatography-Mass Spectrometry; Gastric Acidity Determination; Hydrogen-Ion Concentration; Kinetics; Magnetic Resonance Spectroscopy; Nucleoside Deaminases; Nucleosides; Tetrahydrouridine; Uridine | 1986 |
In vivo studies on high-dose 1-beta-D-arabinofuranosylcytosine (HDara-C) and 1-beta-D-arabinofuranosyluracil (ara-U) with respect to pharmacokinetics, cell kinetics, and cytotoxicity in a rat myelocytic leukemia model (BNML).
Topics: Animals; Arabinofuranosyluracil; Cell Cycle; Colony-Forming Units Assay; Cytarabine; Cytidine Deaminase; Disease Models, Animal; Half-Life; Humans; Kinetics; Leukemia, Myeloid, Acute; Nucleoside Deaminases; Rats; Uridine | 1985 |
Pharmacology and toxicology of a seven-day infusion of 1-beta-D-arabinofuranosylcytosine plus uridine in dogs.
Topics: Adenosine Triphosphate; Animals; Bone Marrow; Cytarabine; Diarrhea; Dogs; Drug Synergism; Leukocyte Count; Liver; Male; Uridine | 1985 |
Effect of uracil arabinoside on metabolism and cytotoxicity of cytosine arabinoside in L5178Y murine leukemia.
Topics: Animals; Arabinofuranosyluracil; Cytarabine; Cytotoxicity, Immunologic; Drug Interactions; Humans; Kinetics; Leukemia L5178; Leukemia, Experimental; Tumor Stem Cell Assay; Uridine | 1985 |
[Estimation of tumor sensitivity in vitro. II. Studies with the solid Ehrlich carcinoma of the mouse and the GW 77, a heterotransplanted human carcinoma].
Topics: Animals; Antibiotics, Antineoplastic; Autoradiography; Carcinoma; Carcinoma, Ehrlich Tumor; Colonic Neoplasms; Cricetinae; Culture Media; Cytarabine; Dactinomycin; DNA, Neoplasm; Humans; Hydroxyurea; Mice; Neoplasm Transplantation; Neoplasms, Experimental; Nucleosides; RNA, Neoplasm; Thymidine; Triaziquone; Tritium; Uridine | 1970 |
[Selective tumour chemotherapy using oncobiograms (author's transl)].
Topics: Animals; Antineoplastic Agents; Bleomycin; Cricetinae; Culture Techniques; Cytarabine; Dactinomycin; Daunorubicin; Doxorubicin; Drug Evaluation; Drug Resistance; Fluorouracil; Humans; Methods; Methotrexate; Neoplasm Transplantation; Neoplasms; Neoplasms, Experimental; Procarbazine; Radioisotopes; Rats; Scintillation Counting; Thymidine; Triaziquone; Uridine | 1974 |
[The effects of cytostatic agents on short-term cultures (3H-uridine incorporation) and tissue cultures (cell counts) from human tumors (author's transl)].
Topics: Antineoplastic Agents; Bleomycin; Cell Count; Cell Transformation, Neoplastic; Cells, Cultured; Cytarabine; Dactinomycin; Daunorubicin; Doxorubicin; Drug Evaluation, Preclinical; Female; Fluorouracil; Humans; In Vitro Techniques; Methods; Methotrexate; Neoplasms; Ovarian Neoplasms; Podophyllin; Suspensions; Time Factors; Triaziquone; Tritium; Uridine | 1974 |
Effects of cytosine arabinoside on differential gene expression in embryonic neural retina. I. Accumulation of glutamine synthetase with suppression of macromolecular synthesis.
Topics: Animals; Carbon Radioisotopes; Chick Embryo; Cycloheximide; Cytarabine; Dactinomycin; DNA; Genes; Genes, Regulator; Glutamate-Ammonia Ligase; Macromolecular Substances; Neurons; Phenotype; Retina; RNA; Tritium; Uridine | 1974 |
Nucleotide metabolism in tissue culture cells at low temperatures. II. Feedback mechanisms during the synthesis of nucleoside and deoxynucleoside triphosphates at low temperatures.
Topics: Animals; Chick Embryo; Cold Temperature; Culture Techniques; Cytarabine; Dactinomycin; Depression, Chemical; Feedback; Fibroblasts; Nucleotides; Phosphoric Acids; Temperature; Thymidine; Tritium; Uracil Nucleotides; Uridine | 1967 |
Studies on a new mechanism of resistance of L5178Y murine leukemia cells to cytosine arabinoside.
Topics: Animals; Chromosomes; Culture Techniques; Cytarabine; Cytosine Nucleotides; Depression, Chemical; Hydrogen-Ion Concentration; Leukemia; Leukemia Virus, Murine; Leukemia, Experimental; Mice; Mutation; Nucleosides; Nucleotides; Solubility; Staining and Labeling; Thymidine; Tritium; Uridine | 1968 |
Identification of presumptive histone messenger RNA in rapidly labelled polysomal RNA of mouse myelomas.
Topics: Animals; Centrifugation, Density Gradient; Cytarabine; Edetic Acid; Electrophoresis, Polyacrylamide Gel; Female; Histones; Isotope Labeling; Mice; Mice, Inbred BALB C; Multiple Myeloma; Neoplasms, Experimental; Plasmacytoma; Polyribosomes; RNA, Messenger; RNA, Ribosomal; Spectrophotometry, Ultraviolet; Time Factors; Tritium; Uridine | 1973 |
Vaccinia virus polypeptide synthesis: sequential appearance and stability of pre- and post-replicative polypeptides.
Topics: Animals; Autoradiography; Carbon Radioisotopes; Cell Line; Cytarabine; DNA, Viral; Electrophoresis, Polyacrylamide Gel; Haplorhini; Hydroxyurea; Kidney; Methionine; Peptide Biosynthesis; Protein Hydrolysates; Sulfur Radioisotopes; Thymidine; Time Factors; Tritium; Uridine; Vaccinia virus; Virus Replication | 1974 |
Release of C-type particles from normal rat thymus cultures and those infected with Moloney leukemia virus.
Topics: Animals; Biological Assay; Cell Line; Centrifugation, Density Gradient; Culture Techniques; Cytarabine; Dactinomycin; DNA, Viral; Floxuridine; Fluorescent Antibody Technique; Immune Sera; Mice; Microscopy, Electron; Moloney murine leukemia virus; Rats; RNA, Viral; Spectrum Analysis; Thymus Gland; Tritium; Ultraviolet Rays; Uridine; Viral Proteins | 1971 |
Critical cell proliferation as a prerequisite for differentiation of mammary epithelial cells.
Topics: Animals; Caseins; Cell Differentiation; Cytarabine; Epithelium; Estradiol; Female; Floxuridine; Glucosephosphate Dehydrogenase; Hydrocortisone; Insulin; Lactalbumin; Lactose Synthase; Mammary Glands, Animal; Mice; Mitosis; Pregnancy; Prolactin; Uridine | 1973 |
The influence of non-neuronal cells on catecholamine and acetylcholine synthesis and accumulation in cultures of dissociated sympathetic neurons.
Topics: Acetylcholine; Animals; Catecholamines; Cells, Cultured; Choline; Cytarabine; Fibroblasts; Floxuridine; Ganglia, Autonomic; Glioma; Neurons; Rats; Sympathetic Nervous System; Uridine | 1974 |
Biochemical and pharmacological studies with 1-beta-D-arabinofuranosylcytosine in man.
Topics: Adult; Carcinoma, Hepatocellular; Chromatography, Paper; Cytarabine; DNA; Female; Humans; Leukemia, Myeloid; Leukocytes; Liver Neoplasms; Lymphoma, Large B-Cell, Diffuse; Male; Melanoma; Middle Aged; Nucleosides; RNA; RNA, Transfer; Tritium; Uracil Nucleotides; Uridine | 1966 |
[Giant cell formation and virus-specific antigens of herpesvirus hominis: information flow from the parental DNA].
Topics: Animals; Antigens; Autoradiography; Cell Line; Cytarabine; Cytopathogenic Effect, Viral; Hydroxyurea; Kidney; Mitomycins; Rabbits; Radiation Effects; RNA; Simplexvirus; Thymidine; Tritium; Ultraviolet Rays; Uridine | 1969 |
Interferon production by human leukocytes in vitro: some biological characteristics.
Topics: Antimetabolites; Bone Marrow; Bone Marrow Cells; Carbon Isotopes; Culture Techniques; Cytarabine; Dactinomycin; DNA, Viral; Humans; Interferons; Leukemia; Leukocytes; Parainfluenza Virus 1, Human; Phenylalanine; Puromycin; Thymidine; Uridine; Virus Cultivation; Virus Replication | 1969 |
[Reciprocal dissociativity of DNA synthesis and giant cell formation in Herpesvirus hominis caused by cytosine arabinoside and compound 48-80].
Topics: Animals; Culture Techniques; Cytarabine; Cytopathogenic Effect, Viral; Depression, Chemical; DNA, Viral; Genetics, Microbial; Kidney; p-Methoxy-N-methylphenethylamine; Rabbits; Simplexvirus; Thymidine; Tritium; Uridine | 1970 |
Polyribosomes of cells abortively or productively infected with adenovirus, papovavirus, or their hybrid.
Topics: Adenoviridae; Animals; Cell Line; Centrifugation, Density Gradient; Complement Fixation Tests; Culture Techniques; Cytarabine; Edetic Acid; Embryo, Mammalian; Genetics, Microbial; Haplorhini; Humans; Hybridization, Genetic; Kidney; Ribonucleases; Ribosomes; Simian virus 40; Sucrose; Tritium; Uridine; Virus Replication | 1969 |
Appearance of Epstein-Barr virus-associated antigens in infected Raji cells.
Topics: Absorption; Antigens; Cell Line; Cell Membrane; Cells, Cultured; Cytarabine; DNA; Female; Fluorescent Antibody Technique; Herpesviridae; Herpesvirus 4, Human; Humans; Idoxuridine; Immune Sera; Lymphocytes; Neutralization Tests; Phenylalanine; Protein Biosynthesis; Puromycin; RNA; Thymidine; Time Factors; Tritium; Uridine; Viral Proteins | 1971 |
Metabolic requirements for infection by Rous sarcoma virus. 3. The synthesis on viral DNA.
Topics: Animals; Avian Sarcoma Viruses; Carbon Isotopes; Cell Transformation, Neoplastic; Cells, Cultured; Chick Embryo; Cycloheximide; Cytarabine; Deoxyadenosines; Deoxyribonucleosides; DNA; DNA, Viral; Fluorine; Idoxuridine; Leucine; Phenylalanine; Phosphates; Phosphorus Isotopes; RNA; Time Factors; Tritium; Uridine; Viral Proteins; Virus Replication | 1972 |
Pattern of protein synthesis in monkey cells infected by simian virus 40.
Topics: Amino Acid Sequence; Animals; Autoradiography; Cell Line; Cytarabine; DNA Replication; DNA, Viral; Electrophoresis, Disc; Floxuridine; Haplorhini; Kidney; Methionine; Peptides; Phosphorus Isotopes; Simian virus 40; Sulfur Isotopes; Thymidine; Time Factors; Tritium; Trypsin; Uridine; Viral Proteins | 1972 |
[Viral complications of renal transplantation].
Topics: Azathioprine; Cytarabine; Cytomegalovirus; DNA Viruses; DNA, Viral; Hepatitis A; Hepatitis B virus; Herpesviridae Infections; Humans; Immunosuppression Therapy; Kidney Transplantation; Liver Cirrhosis; Transplantation Immunology; Transplantation, Homologous; Uridine; Virus Diseases | 1971 |
Nuclear polyadenosine diphosphoribosylation during restricted macromolecular synthesis of HeLa cells.
Topics: Adenine Nucleotides; Adenosine Diphosphate; Carbon Isotopes; Cell Nucleus; Chromatin; Cycloheximide; Cytarabine; Dactinomycin; Deoxyadenosines; DNA; HeLa Cells; Hydroxyurea; NAD; Nucleoside Diphosphate Sugars; Nucleotidyltransferases; Protein Biosynthesis; Ribosomes; RNA Nucleotidyltransferases; Thymidine; Tritium; Uridine; Valine | 1972 |
Isolation and characterization of simian virus 40 ribonucleic acid.
Topics: Animals; Cell Line; Cell Nucleus; Centrifugation, Density Gradient; Chemical Precipitation; Cytarabine; Cytoplasm; Dimethyl Sulfoxide; DNA, Viral; Electrophoresis, Polyacrylamide Gel; Formamides; Haplorhini; Kidney; Molecular Weight; Nucleic Acid Hybridization; Phosphorus Isotopes; RNA, Viral; Simian virus 40; Tritium; Uridine | 1972 |
Monkeypox virus (MPV). II. Uncoating and nucleic acid synthesis.
Topics: Animals; Cell Line; Cell Nucleus; Centrifugation, Density Gradient; Cytarabine; Cytoplasm; Dactinomycin; Deoxyribonucleases; DNA; DNA, Viral; Haplorhini; Kidney; Monkey Diseases; Poxviridae; Poxviridae Infections; RNA; RNA, Messenger; Thymidine; Time Factors; Tritium; Uridine; Virus Cultivation; Virus Replication | 1972 |
Inhibition of replication of lactic dehydrogenase virus by actinomycin.
Topics: Animals; Culture Techniques; Cytarabine; Dactinomycin; DNA; Drug Resistance, Microbial; Floxuridine; Interferons; L Cells; L-Lactate Dehydrogenase; Mice; Mice, Inbred Strains; Newcastle disease virus; RNA; RNA Viruses; Thymidine; Time Factors; Tritium; Uridine; Vesicular stomatitis Indiana virus; Virus Diseases; Virus Replication | 1973 |
Enancement of uptake of Simian virus 40 by nuclei of permissive cells.
Topics: Animals; Cell Nucleus; Cells, Cultured; Culture Media; Cycloheximide; Cytarabine; Cytoplasm; Dactinomycin; DNA; Floxuridine; Haplorhini; Histones; Hydroxyurea; Kidney; Kinetics; Magnesium Sulfate; RNA; Simian virus 40; Thymidine; Tritium; Uridine | 1973 |
Control of gene expression in rat cells transformed by a cold-sensitive murine sarcoma virus (MSV) mutant.
Topics: Animals; Cell Line; Cell Transformation, Neoplastic; Cell-Free System; Cold Temperature; Cytarabine; Dactinomycin; DNA-Directed RNA Polymerases; Gammaretrovirus; Genes; Glucosamine; Glucose; Kidney; Mutation; Nucleic Acid Hybridization; Phenotype; Protein Biosynthesis; Puromycin; Rats; RNA, Viral; Thymidine; Tritium; Uridine; Viral Proteins | 1973 |
Persistence of late SV40 genome transcription after inhibition of DNA relication by cytosine arabinoside.
Topics: Animals; Cell Line; Centrifugation, Density Gradient; Cytarabine; DNA Replication; DNA, Viral; Genes; Haplorhini; Isotope Labeling; Kidney; Nucleic Acid Hybridization; Ribonucleases; Simian virus 40; Spectrophotometry, Ultraviolet; Thymidine; Time Factors; Transcription, Genetic; Tritium; Uridine | 1974 |
Early and late viral-specific polyribosomal RNA in herpes virus-1 and -2-infected rabbit kidney cells.
Topics: Animals; Cells, Cultured; Cytarabine; DNA, Viral; Genes; Kidney; Nucleic Acid Hybridization; Polyribosomes; Rabbits; RNA, Messenger; RNA, Ribosomal; RNA, Viral; Simplexvirus; Species Specificity; Spectrophotometry, Ultraviolet; Transcription, Genetic; Tritium; Uridine; Virus Replication | 1974 |
Isolation of temperature-sensitive mutants from murine leukemic cells (L5178Y).
Topics: Agar; Animals; Cell Line; Cell Separation; Cell Survival; Cytarabine; Deoxycytidine; DNA, Neoplasm; Leucine; Leukemia, Lymphoid; Mesylates; Mice; Mutagens; Mutation; Neoplasm Proteins; RNA, Neoplasm; Temperature; Tritium; Uridine | 1974 |
Effect of inhibitors of nucleic acid synthesis on steroid-mediated induction of tyrosine aminotransferase in hepatoma cell cultures.
Topics: Carbon Isotopes; Culture Techniques; Cycloheximide; Cytarabine; Dactinomycin; Dexamethasone; DNA; Enzyme Induction; Mitomycins; Neoplasms, Experimental; RNA; Thymidine; Tritium; Tyrosine Transaminase; Uridine; Valine | 1967 |
Changes in macromolecular synthesis associated with the induction of glutamine synthetase in embryonic retina.
Topics: Animals; Aspartic Acid; Autoradiography; Carbon Isotopes; Cell Fractionation; Centrifugation, Density Gradient; Chick Embryo; Cytarabine; Enzyme Induction; Glutamate-Ammonia Ligase; Hydrocortisone; Macromolecular Substances; Protein Biosynthesis; Proteins; Retina; Ribosomes; Tritium; Uridine | 1971 |
Depression of thymidylate synthetase activity in response to cytosine arabinoside.
Topics: Carbon Isotopes; Cell Line; Cytarabine; Cytidine; DNA; Glycine; Humans; Hypoxanthines; In Vitro Techniques; Leukemia, Lymphoid; Leukocytes; Methyltransferases; Nucleic Acids; RNA; Thymidine; Thymine Nucleotides; Time Factors; Tritium; Uracil Nucleotides; Uridine | 1972 |
Distribution of kinase and deaminase of 1-beta-D-arabinofuranosylcytosine in tissues of man and mouse.
Topics: Aminohydrolases; Animals; Bone Marrow; Bone Marrow Cells; Cytarabine; Deoxycytidine; Humans; Kidney; Leukemia, Lymphoid; Leukemia, Myeloid; Leukemia, Myeloid, Acute; Leukocytes; Liver; Mice; Phosphotransferases; Spleen; Uridine | 1973 |
Metabolic studies of small molecular weight nuclear RNA components in BHK-21 cells.
Topics: Animals; Carcinoma, Ehrlich Tumor; Cell Line; Cell Nucleus; Cricetinae; Cytarabine; Dactinomycin; Deoxyadenosines; Electrophoresis, Polyacrylamide Gel; Half-Life; Kidney; Magnesium; Methionine; Mice; Molecular Weight; Phosphates; Phosphorus Radioisotopes; RNA; RNA, Ribosomal; Spectrophotometry, Ultraviolet; Temperature; Time Factors; Tritium; Uridine | 1974 |
Antineoplastic drug effects on spermatogenesis studied by velocity sedimentation cell separation.
Topics: Animals; Antineoplastic Agents; Cell Differentiation; Cell Fractionation; Cyclophosphamide; Cytarabine; Cytological Techniques; In Vitro Techniques; Leucine; Male; Mice; Mice, Inbred Strains; Procarbazine; Spermatogenesis; Spermatozoa; Thymidine; Time Factors; Tritium; Uridine; Vincristine | 1972 |
A possible role for histone in the synthesis of DNA.
Topics: Acrylates; Animals; Canavanine; Centrifugation, Density Gradient; Chickens; Cycloheximide; Cytarabine; Dactinomycin; DNA; DNA Replication; Erythrocytes; Histones; Indoles; Kinetics; Leucine; Peptide Elongation Factors; Thymidine; Tritium; Tryptophan; Tyrosine; Uridine | 1972 |
The gross and biochemical effects of 1- -D-arabinofuranosyl cytosine on an actinobolin-resistant strain of Streptococcus faecalis.
Topics: Adenine; Anti-Bacterial Agents; Bacterial Proteins; Carbon Isotopes; Cytarabine; Cytosine Nucleotides; DNA, Bacterial; Drug Resistance, Microbial; Enterococcus faecalis; Formates; RNA, Bacterial; Thymidine; Tritium; Uridine | 1973 |
A microbiological assay for cyclocytidine--disposition studies in mice.
Topics: Animals; Biological Assay; Cytarabine; Cytidine; Deoxycytidine; Enterococcus faecalis; Female; Mice; Nucleosides; Uridine | 1973 |
Inhibition of 1- -D-arabinofuranosyl cytosine phosphorylation in human livers by tetrahydrouridine.
Topics: Animals; Chromatography, Paper; Cricetinae; Cytarabine; Humans; In Vitro Techniques; Leukemia, Lymphoid; Liver; Lung Neoplasms; Neurofibroma; Nucleotides; Oxidative Phosphorylation; Phosphotransferases; Postmortem Changes; Rats; Species Specificity; Spectrophotometry, Ultraviolet; Time Factors; Uracil Nucleotides; Uridine | 1972 |
Studies on nucleoside deaminase. Increase in activity in HeLa cell cultures caused by cytosine arabinoside.
Topics: Alkaline Phosphatase; Aminohydrolases; Antimetabolites; Carbon Isotopes; Cell Fractionation; Culture Media; Cycloheximide; Cytarabine; Cytidine; Deamination; DNA; DNA Nucleotidyltransferases; Glucosephosphate Dehydrogenase; HeLa Cells; L-Lactate Dehydrogenase; Leucine; Methotrexate; Nucleosides; Protein Biosynthesis; Thymidine; Time Factors; Tritium; Uridine | 1973 |
Inhibition of pancreatic ribonuclease A by arabinonucleotides.
Topics: Animals; Arabinose; Cattle; Chromatography, Paper; Cytarabine; Cytidine; Cytosine Nucleotides; Kinetics; Nucleosides; Nucleotides; Oligonucleotides; Pancreas; Phosphoric Acids; Photometry; Ribonucleases; Ribose; Spectrophotometry, Ultraviolet; Structure-Activity Relationship; Uracil Nucleotides; Uridine | 1973 |
Messenger RNA turnover in mouse L cells.
Topics: Adenine Nucleotides; Animals; Cell Division; Centrifugation, Density Gradient; Cytarabine; Electrophoresis, Polyacrylamide Gel; Histones; Kinetics; L Cells; Mathematics; Mice; Phosphorus Radioisotopes; Polyribosomes; RNA, Messenger; RNA, Ribosomal; RNA, Transfer; Spectrophotometry, Ultraviolet; Time Factors; Tritium; Uridine | 1973 |
Inhibition of replication and differentiation in malignant mouse neuroblasts.
Topics: Amino Acids; Animals; Cell Differentiation; Cell Division; Cell Line; Cell Survival; Cytarabine; DNA Replication; Methotrexate; Mice; Microscopy, Electron; Neoplasm Proteins; Neoplasms, Experimental; Neuroblastoma; RNA; Thymidine; Tritium; Uridine | 1973 |
Patterns of transcription of messengers containing poly A in vaccinia virus-infected cells.
Topics: Animals; Cell Line; Cycloheximide; Cytarabine; Kidney; Nucleic Acid Hybridization; Phosphorus Radioisotopes; Polynucleotides; Rabbits; RNA, Messenger; RNA, Viral; Transcription, Genetic; Tritium; Uridine; Vaccinia virus | 1974 |
Biochemical studies of a new antitumor agent, O2,2'-cyclocytidine.
Topics: Anhydrides; Animals; Antineoplastic Agents; Bone Marrow; Bone Marrow Cells; Carbon Radioisotopes; Cell Line; Cells, Cultured; Cytarabine; DNA, Neoplasm; Dogs; Dose-Response Relationship, Drug; Drug Resistance; Humans; Hydrolysis; Leukemia L1210; Mice; Mice, Inbred DBA; Neoplasm Transplantation; Thymidine; Time Factors; Transplantation, Homologous; Tritium; Uridine; Valine | 1974 |
The effects of cytostatic drugs on transplanted tumours. An investigation of the correlation between in vivo and in vitro results.
Topics: Adenocarcinoma; Animals; Antineoplastic Agents; Carcinoma 256, Walker; Cricetinae; Cytarabine; Daunorubicin; Fluorouracil; Melanoma; Methotrexate; Mice; Neoplasm Transplantation; Plasmacytoma; Procarbazine; Rats; Thymidine; Tritium; Uridine | 1974 |
The effect of cytosine arabinoside on nucleic acid synthesis in normal and leukaemic human leucocytes in vitro.
Topics: Autoradiography; Culture Techniques; Cytarabine; DNA; Humans; Leukemia, Lymphoid; Leukocytes; RNA; Thymidine; Tritium; Uridine | 1969 |
Enhancement by tetrahydrouridine of 1-beta-D-arabinofuranosylcytosine (cytarabine) oral activity in L1210 leukemic mice.
Topics: Animals; Antineoplastic Agents; Biological Assay; Carbon Isotopes; Cytarabine; Drug Synergism; Enterococcus faecalis; Female; Furans; Humans; Injections, Intraperitoneal; Leukemia L1210; Mice; Nucleosides; Uridine | 1970 |
Biochemical and pharmacologic studies with 1- -D-arabinofuranosylcytosine 5'-adamantoate (NSC-117614), a depot form of cytarabine.
Topics: Animals; Antineoplastic Agents; Carboxylic Acids; Carcinoma, Squamous Cell; Cell Line; Cells, Cultured; Cycloparaffins; Cytarabine; Deamination; Delayed-Action Preparations; Depression, Chemical; DNA, Neoplasm; Half-Life; Haplorhini; Humans; Hydrolysis; In Vitro Techniques; Leukemia L1210; Mice; Neoplasm Proteins; Physostigmine; Plasma; RNA, Neoplasm; Tritium; Uridine | 1971 |
Improved microbiological assay for cytosine arabinoside (NSC-63878).
Topics: Biological Assay; Cytarabine; Deamination; Enterococcus faecalis; Half-Life; Kinetics; Methods; Tritium; Uridine | 1970 |
[Multiplication of viruses. I. Chemical inhibitors and the problem of antiviral chemotherapy].
Topics: Amantadine; Animals; Antibiotics, Antineoplastic; Antiviral Agents; Chemistry, Pharmaceutical; Cytarabine; DNA Replication; Humans; Idoxuridine; Mice; Uridine; Virus Replication; Viruses | 1972 |
Mediated transport of nucleosides in human erythrocytes. Accelerative exchange diffusion of uridine and thymidine and specificity toward pyrimidine nucleosides as permeants.
Topics: Benzyl Compounds; Biological Transport; Carbon Isotopes; Cytarabine; Cytidine; Deoxyribonucleosides; Diffusion; Erythrocytes; Guanosine; Humans; Kinetics; Nitro Compounds; Ribonucleosides; Structure-Activity Relationship; Sulfides; Thymidine; Uridine | 1972 |
The synthesis of poxvirus-specific RNA in interferon-treated cells.
Topics: Animals; Autoradiography; Carbon Isotopes; Cells, Cultured; Chick Embryo; Chromatography, Ion Exchange; Cytarabine; Cytopathogenic Effect, Viral; DNA, Viral; Fibroblasts; Genetic Code; Interferons; Isotope Labeling; L Cells; Mice; Newcastle disease virus; Nucleic Acid Hybridization; Orthomyxoviridae; RNA, Viral; Thymidine; Tritium; Uridine; Vaccinia virus; Virus Replication | 1972 |
Nucleoside transport in mammalian cells. Inhibition by colchicine.
Topics: Adenosine; Alkaloids; Aminoisobutyric Acids; Animals; Carbon Isotopes; Carcinoma; Cell Line; Cells, Cultured; Colchicine; Cricetinae; Cytarabine; Dactinomycin; Fetus; Fibroblasts; Guanosine; HeLa Cells; Hexoses; Humans; Lung; Mouth Neoplasms; Nucleic Acids; Nucleosides; Phosphorus Isotopes; Plants, Medicinal; Plants, Toxic; Podophyllum; Skin; Thymidine; Tritium; Uridine | 1972 |
Identification of a developmental program using bromodeoxyuridine.
Topics: Animals; Autoradiography; Bromodeoxyuridine; Cell Fractionation; Centrifugation, Density Gradient; Chick Embryo; Chromosomes; Cytarabine; Dactinomycin; DNA; DNA Replication; Electrophoresis, Polyacrylamide Gel; Erythrocytes; Hemoglobins; Protein Biosynthesis; RNA, Messenger; Spectrophotometry; Thymidine; Uridine | 1972 |
A distinct RNA polymerase activity, synthesizing 5-5 s, 5 s and 4 s RNA in nuclei from adenovirus 2-infected HeLa cells.
Topics: Adenoviridae; Cell Nucleus; Chromosomes; Cytarabine; DNA-Directed RNA Polymerases; Electrophoresis; HeLa Cells; Humans; Kinetics; Manganese; Molecular Weight; Mycotoxins; Nucleic Acid Hybridization; RNA; RNA, Transfer; RNA, Viral; Transcription, Genetic; Tritium; Uridine | 1972 |
Hormonal induction of dehydrogenase enzymes in mammary gland in vitro.
Topics: Animals; Carbon Isotopes; Colchicine; Corticosterone; Cycloheximide; Cytarabine; Dactinomycin; Enzyme Induction; Female; Glucosephosphate Dehydrogenase; Insulin; Mammary Glands, Animal; Mice; Organ Culture Techniques; Phosphogluconate Dehydrogenase; Pregnancy; Prolactin; RNA; Uridine | 1971 |
The effects of oestradiol on nucleoside transport in rat uterus.
Topics: Amino Acids; Animals; Biological Transport; Body Fluids; Carbon Isotopes; Cytarabine; Diffusion; Estradiol; Female; In Vitro Techniques; Nucleosides; Purines; Pyrimidines; Rats; Sucrose; Tritium; Uridine; Uterus | 1971 |
A micro-system for screening anti-leukemic drugs utilizing human whole blood.
Topics: Adult; Aged; Cytarabine; DNA; Evaluation Studies as Topic; Female; Humans; Infant; Leukemia; Leukocytes; Male; Mercaptopurine; Middle Aged; Quinacrine; RNA; Thymidine; Tritium; Uridine | 1971 |
Incorporation of arabinosyl cytosine into 2-7S ribonucleic acid and cell death.
Topics: Acrylamides; Animals; Cell Line; Cell Survival; Cells, Cultured; Centrifugation, Density Gradient; Cytarabine; In Vitro Techniques; Leukemia, Experimental; Mice; RNA, Neoplasm; Tritium; Uridine | 1971 |
Transport of pyrimidine nucleosides across human erythrocyte membranes.
Topics: ABO Blood-Group System; Biological Transport; Carbon Isotopes; Cell Membrane; Cytarabine; Cytidine; Depression, Chemical; Erythrocytes; Humans; Inosine; Kinetics; Purines; Sucrose; Thymidine; Tritium; Uridine | 1971 |
Prediction of in vivo cytotoxicity of chemotherapeutic agents by their effect on malignant leukocytes in vitro.
Topics: Blood Cell Count; Cytarabine; DNA; Humans; In Vitro Techniques; Injections, Intravenous; Leukemia; Leukemia, Lymphoid; Leukemia, Myeloid, Acute; Lymphoma, Non-Hodgkin; Mercaptopurine; Multiple Myeloma; Prednisone; RNA; Tritium; Uridine; Vincristine | 1967 |
Prediction of in vivo cytotoxicity of chemotherapeutic agents by their in vitro effect on leukocytes from patients with acute leukemia.
Topics: Adolescent; Adult; Carbon Isotopes; Centrifugation; Culture Techniques; Cytarabine; Depression, Chemical; DNA; Glucocorticoids; Humans; Leukemia, Lymphoid; Leukemia, Monocytic, Acute; Leukocytes; RNA; Thymidine; Tritium; Uridine; Vincristine | 1968 |
The effects of chemotherapeutic agents on the RNA metabolism of 90Sr-induced rat chloroleukemia.
Topics: Animals; Asparaginase; Cytarabine; Daunorubicin; Depression, Chemical; Hydrocortisone; In Vitro Techniques; Leukemia, Myeloid; Leukemia, Radiation-Induced; Poly I-C; Polynucleotides; Rats; RNA, Neoplasm; Strontium Isotopes; Tritium; Uridine; Vinblastine | 1971 |
Studies on the mechanism of action of 1-beta-D-arabinofuranosylcytosine as an inhibitor of DNA synthesis in human leukemic leukocytes.
Topics: Animals; Binding Sites; Cytarabine; DNA Nucleotidyltransferases; DNA, Neoplasm; Humans; Hydroxyurea; In Vitro Techniques; Leukemia, Experimental; Leukocytes; Tritium; Uridine | 1969 |
An analysis of melanogenesis in cultured chick embryo spinal ganglia.
Topics: Animals; Cell Differentiation; Chick Embryo; Culture Techniques; Cytarabine; Dactinomycin; DNA; Ganglia, Spinal; Melanins; Motion Pictures; RNA; Thymidine; Tritium; Uridine | 1970 |
The role of DNA synthesis in virus replication and the morphological transformation of normal mouse embryo cells by MSV (Moloney).
Topics: Animals; Cell Division; Cell Transformation, Neoplastic; Culture Techniques; Cytarabine; DNA; Fibroblasts; Mice; Moloney murine leukemia virus; Radiation Effects; RNA; Thymidine; Tritium; Uridine; Virus Replication | 1970 |
Sparing action of uridine on the activity of arabinosylcytosine with normal and leukemic mice.
Topics: Animals; Chromatography; Cytarabine; Cytosine; Drug Synergism; Leukemia L1210; Male; Mice; Nucleosides; Spleen; Thymidine; Tritium; Uracil Nucleotides; Uridine | 1968 |
Effects of uracil derivatives on phosphorylation of arabinosylcytosine.
Topics: Adenosine Triphosphate; Animals; Carbon Isotopes; Cytarabine; Dialysis; In Vitro Techniques; Leukemia L1210; Magnesium; Mice; Nucleosides; Nucleotides; Oxidative Phosphorylation; Spleen; Tritium; Uracil Nucleotides; Uridine | 1968 |
Viruses and renal carcinoma of Rana pipiens. VI. Interrelationships of macromolecular synthesis and infectious virus production in frog virus 3-infected BHK 21/13 cells.
Topics: Adenine; Animals; Anura; Carbon Isotopes; Culture Techniques; Cycloheximide; Cytarabine; Dactinomycin; DNA; DNA, Viral; Herpesviridae; Hydroxyurea; Idoxuridine; Inclusion Bodies, Viral; Kidney Neoplasms; Leucine; Neoplasms, Experimental; Oncogenic Viruses; Protein Biosynthesis; RNA; RNA, Viral; Thymidine; Tritium; Uridine; Viral Proteins; Virus Replication | 1968 |
Transformation by murine sarcoma virus: fixation (deoxyribonucleic acid synthesis) and development.
Topics: Animals; Carbon Isotopes; Cell Transformation, Neoplastic; Culture Techniques; Cytarabine; DNA; Leucine; Oncogenic Viruses; Protein Biosynthesis; Rats; RNA; Sarcoma, Experimental; Thymidine; Time Factors; Tritium; Uridine | 1968 |
Effect of cytosine arabinoside on the replication of the Moloney sarcoma virus in 3T3 cell cultures.
Topics: Animals; Clone Cells; Culture Techniques; Cytarabine; Cytosine Nucleotides; DNA; DNA, Viral; Mice; Moloney murine leukemia virus; RNA; RNA, Viral; Thymidine; Time Factors; Uridine; Virus Replication | 1969 |
Requirements for RNA and DNA synthesis in the transformation of mouse embryo cells by murine sarcoma virus (Moloney).
Topics: Cell Line; Cell Transformation, Neoplastic; Culture Techniques; Cytarabine; Dactinomycin; DNA; Embryo, Mammalian; Embryo, Nonmammalian; Mitomycins; Moloney murine leukemia virus; Neoplasms, Experimental; RNA; Thymidine; Tritium; Uridine; Virus Replication | 1969 |
Puromycin-induced necrosis of crypt cells of the small intestine of mouse.
Topics: Animals; Antimetabolites; Autoradiography; Cell Division; Cytarabine; Dactinomycin; DNA; Heart; Intestine, Small; Leucine; Liver; Male; Mice; Necrosis; Nucleosides; Protein Biosynthesis; Proteins; Puromycin; RNA; Spleen; Thymidine; Tritium; Uridine | 1966 |
Inhibition of Rauscher murine leukemia virus growth in vitro by actinomycin D.
Topics: Animals; Centrifugation, Density Gradient; Culture Techniques; Cytarabine; Dactinomycin; Detergents; DNA; Mice; Phosphorus Isotopes; Rauscher Virus; RNA, Viral; Thymidine; Tritium; Uridine; Virus Cultivation | 1967 |
The relation of DNA synthesis to RNA synthesis in developing frog embryos.
Topics: Animals; Anura; Carbon Isotopes; Cell Division; Cytarabine; DNA; Embryo, Nonmammalian; Lithium; RNA; Uridine | 1967 |
Acute cerebellar toxicity after high-dose cytarabine associated with CNS accumulation of its metabolite, uracil arabinoside.
Topics: Arabinofuranosyluracil; Carcinoma, Small Cell; Cerebellar Diseases; Cytarabine; Humans; Lung Neoplasms; Male; Middle Aged; Uridine | 1984 |
Effect of 3-deazauridine on the metabolism, toxicity, and antitumor activity of azacitidine in mice bearing L1210 leukemia sensitive and resistant to cytarabine.
Topics: 3-Deazauridine; Animals; Azacitidine; Chromatography, High Pressure Liquid; Cytarabine; Drug Therapy, Combination; Lethal Dose 50; Leukemia L1210; Mice; Mice, Inbred DBA; Purine Nucleotides; Pyrimidine Nucleotides; Uridine | 1983 |
Modulation of 1-beta-D-arabinofuranosylcytosine metabolism and cytotoxicity in L1210 cells by fluoropyrimidine pretreatment.
Topics: Animals; Arabinofuranosylcytosine Triphosphate; Cell Line; Cell Survival; Clone Cells; Cytarabine; Deoxyribonucleotides; Deoxyuridine; Drug Interactions; Floxuridine; Fluorodeoxyuridylate; Fluorouracil; Leukemia L1210; Mice; Uridine | 1982 |
Treatment of primary acute genital herpes in guinea pigs by intraperitoneal administration of fluoropyrimidines.
Topics: Acyclovir; Animals; Antiviral Agents; Arabinofuranosyluracil; Cytarabine; Female; Foscarnet; Guinea Pigs; Herpes Genitalis; Injections, Intraperitoneal; Male; Phosphonoacetic Acid; Uridine; Virus Replication | 1984 |
Effects of tetrahydrouridine on the uptake and metabolism of 1-beta-D-arabinofuranosylcytosine in human normal and leukemic cells.
Topics: Bone Marrow; Cells, Cultured; Cytarabine; Humans; Leukemia; Leukemia, Lymphoid; Leukemia, Myeloid; Leukemia, Myeloid, Acute; Leukocytes; Phosphotransferases; Tetrahydrouridine; Uridine | 1980 |
S-substituted derivatives of 6-mercaptopurine ribosides interact both with the transport and metabolic phosphorylation of uridine by virus-transformed hamster fibroblasts.
Topics: Animals; Cell Line; Cell Transformation, Viral; Cricetinae; Cytarabine; Deoxyglucose; Inosine; Kinetics; Mesocricetus; Phosphorylation; Sarcoma Viruses, Murine; Thioinosine; Uridine | 1980 |
Tetrahydrouridine specifically facilitates deoxycytidine incorporation into herpes simplex virus DNA.
Topics: Cytarabine; Deoxycytidine; DNA, Viral; HeLa Cells; Simplexvirus; Tetrahydrouridine; Uridine | 1981 |
Distribution, metabolism, and excretion of 1-(2-fluoro-2-deoxy-beta-D- arabinofuranosyl)thymine and 1-(2-fluoro-2-deoxy-beta-D-arabinofuranosyl)-5- iodocytosine.
Topics: Absorption; Animals; Arabinofuranosyluracil; Chromatography, High Pressure Liquid; Cytarabine; Digestive System; Dogs; Female; Kidney; Male; Metabolic Clearance Rate; Mice; Rats; Simplexvirus; Species Specificity; Tissue Distribution; Uridine; Virus Replication | 1983 |
Epstein-Barr virus: inhibition of replication by three new drugs.
Topics: Acyclovir; Antiviral Agents; Arabinofuranosyluracil; Bromodeoxyuridine; Cytarabine; DNA Replication; Herpesvirus 4, Human; Uridine; Virus Replication | 1983 |
Sensitive radioimmunoassay for cytarabine and uracil arabinoside in plasma.
Topics: Animals; Antibody Specificity; Arabinofuranosyluracil; Cross Reactions; Cytarabine; Haptens; Metabolic Clearance Rate; Mice; Radioimmunoassay; Uridine | 1984 |
High-performance liquid chromatographic assay for cytosine arabinoside, uracil arabinoside and some related nucleosides.
Topics: Arabinofuranosyluracil; Child; Chromatography, High Pressure Liquid; Cytarabine; Cytidine; Deoxycytidine; Humans; Infusions, Parenteral; Kinetics; Leukemia, Myeloid, Acute; Uridine | 1983 |
Urinary excretion of beta-aminoisobutyrate and pseudouridine in acute and chronic myeloid leukemia.
Topics: Adult; Aminoisobutyric Acids; Cytarabine; Daunorubicin; Female; Humans; Leukemia, Myeloid; Leukemia, Myeloid, Acute; Leukocyte Count; Male; Middle Aged; Pseudouridine; Uridine | 1983 |
Macromolecular and cell cycle effects of different classes of agents inducing the maturation of human myeloblastic leukemia (ML-1) cells.
Topics: Cell Cycle; Cell Differentiation; Cell Line; Cycloheximide; Cytarabine; Dactinomycin; Daunorubicin; DNA Replication; Humans; Kinetics; Leucine; Leukemia, Myeloid, Acute; Protein Biosynthesis; Thymidine; Transcription, Genetic; Tretinoin; Tritium; Uridine | 1984 |
Therapeutic activities of 1-(2-fluoro-2-deoxy-beta-D-arabinofuranosyl)-5-iodocytosine and -thymine alone and in combination with acyclovir and vidarabine in mice infected intracerebrally with herpes simplex virus.
Topics: Acyclovir; Administration, Oral; Animals; Antiviral Agents; Arabinofuranosyluracil; Brain; Cytarabine; Drug Therapy, Combination; Encephalitis; Female; Herpes Simplex; Injections, Intraperitoneal; Mice; Uridine; Vidarabine | 1983 |
Simultaneous analysis of 1-beta-D-arabinofuranosylcytosine, 1-beta-D-arabinofuranosyluracil and sodium salicylate in biological samples by high-performance liquid chromatography.
Topics: Animals; Arabinofuranosyluracil; Chromatography, High Pressure Liquid; Cytarabine; Dogs; Sodium Salicylate; Suppositories; Time Factors; Uridine | 1983 |
Alteration of the pharmacokinetics of high-dose ara-C by its metabolite, high ara-U in patients with acute leukemia.
Topics: Acute Disease; Arabinofuranosyluracil; Chromatography, High Pressure Liquid; Cytarabine; Cytidine Deaminase; Dose-Response Relationship, Drug; Humans; Infusions, Parenteral; Kinetics; Leukemia; Models, Biological; Nucleoside Deaminases; Radioimmunoassay; Time Factors; Uridine | 1983 |
Comparison of 2'-fluoro-arabinosyl pyrimidine nucleosides and 1-beta-D-arabinofuranosylcytosine on immunological parameters in vitro.
Topics: Animals; Antibody Formation; Antibody-Producing Cells; Arabinofuranosyluracil; Cell Survival; Cytarabine; Immune Tolerance; Mice; Spleen; Uridine | 1983 |
Cell cycle arrest as a basis of enhancement of 1-beta-D-arabinofuranosylcytosine anabolism in human lymphoblastoid RPMI 6410 cells cultured with 3-deazauridine.
Topics: 3-Deazauridine; Cell Cycle; Cell Division; Cells, Cultured; Cytarabine; HeLa Cells; Humans; Kinetics; Lymphoma, Non-Hodgkin; Neoplasms, Experimental; Phosphorylation; Time Factors; Uridine | 1981 |
Influence of tetrahydrouridine on the pharmacokinetics of intrathecally administered 1-beta-D-arabinofuranosylcytosine.
Topics: Animals; Cytarabine; Cytidine Deaminase; Half-Life; Injections, Intravenous; Injections, Spinal; Macaca mulatta; Male; Tetrahydrouridine; Uridine | 1982 |
Simultaneous determination of 1-beta-D-arabinofuranosylcytosine 5'-triphosphate and 3-deazauridine 5'-triphosphate in human leukemia cells by high-performance liquid chromatography.
Topics: 3-Deazauridine; Arabinofuranosylcytosine Triphosphate; Arabinonucleotides; Cells, Cultured; Chromatography, High Pressure Liquid; Cytarabine; Cytidine Triphosphate; Humans; Leukemia; Leukemia, Lymphoid; Leukemia, Myeloid, Acute; Uracil Nucleotides; Uridine; Uridine Triphosphate | 1980 |
Potent antiviral 2'-fluoro-arabinosyl pyrimidine nucleosides: lack of mutagenic activity.
Topics: Animals; Antiviral Agents; Arabinofuranosyluracil; Cell Line; Cricetinae; Cricetulus; Cytarabine; DNA; Liver; Mutagenicity Tests; Rats; Rats, Inbred Strains; Salmonella typhimurium; Uridine | 1982 |
[The simultaneous determination of Ara-U and Ara-C, urinary metabolites of N4-behenoyl-1-beta-D-arabinofuranosylcytosine by mass fragmentography (author's transl)].
Topics: Antineoplastic Agents; Arabinofuranosyluracil; Cytarabine; Gas Chromatography-Mass Spectrometry; Humans; Uridine | 1982 |
Biochemical effects of 2'-fluoro-5-methyl-1-beta-D-arabinofuranosyluracil and 2'-fluoro-5-iodo-1-beta-D-arabinofuranosylcytosine in mouse leukemic cells sensitive and resistant to 1-beta-D-arabinofuranosylcytosine.
Topics: Animals; Arabinofuranosyluracil; Cell Survival; Cytarabine; Deoxycytidine; DNA Replication; Kinetics; Leukemia L1210; Leukemia, Experimental; Mice; Thymidine; Uridine | 1982 |
Quantitative autoradiographic mapping of herpes simplex virus encephalitis with a radiolabeled antiviral drug.
Topics: Animals; Antiviral Agents; Arabinofuranosyluracil; Autoradiography; Cytarabine; Encephalitis; Herpes Simplex; Rats; Uridine | 1982 |
Determination of 1-beta-D-arabinofuranosylcytosine and 1-beta-D-arabinofuranosyluracil in human plasma by high-performance liquid chromatography.
Topics: Arabinofuranosyluracil; Chromatography, High Pressure Liquid; Cytarabine; Humans; Leukemia; Uridine | 1981 |
Determination of cytarabine and uracil arabinoside in human plasma and cerebrospinal fluid by high-performance liquid chromatography.
Topics: Arabinofuranosyluracil; Chromatography, High Pressure Liquid; Cytarabine; Humans; Leukemia; Time Factors; Uridine | 1981 |
In vivo cellular kinetic and pharmacological studies of 1-beta-D-arabinofuranosylcytosine and 3-deazauridine chemotherapy for relapsing acute leukemia.
Topics: 3-Deazauridine; Adolescent; Adult; Aged; Cell Cycle; Cytarabine; Drug Administration Schedule; Drug Therapy, Combination; Female; Humans; Leukemia; Male; Metabolic Clearance Rate; Middle Aged; Uridine | 1981 |
Mouse strain differences in induction of micronuclei by base analogues and nucleosides.
Topics: Adenine; Animals; Bromodeoxyuridine; Bromouracil; Cytarabine; Erythrocytes; Female; Floxuridine; Guanosine; Mercaptopurine; Mice; Mice, Inbred BALB C; Mice, Inbred C57BL; Mice, Inbred DBA; Micronucleus Tests; Mitogens; Nucleosides; Purines; Pyrimidines; Species Specificity; Thymidine; Uridine | 1993 |
Seeking the nucleoside transporter.
Topics: Animals; Antimetabolites, Antineoplastic; Carrier Proteins; Cell Membrane; Cladribine; Cloning, Molecular; Cytarabine; Deoxycytidine; Erythrocytes; Gemcitabine; Glucose Transporter Type 1; Humans; Leukemia; Lymphoma; Membrane Proteins; Monosaccharide Transport Proteins; Nucleosides; Oocytes; Recombinant Proteins; Uridine; Vidarabine; Xenopus | 1997 |
Cloning of a human nucleoside transporter implicated in the cellular uptake of adenosine and chemotherapeutic drugs.
Topics: Adenosine; Amino Acid Sequence; Animals; Antineoplastic Agents; Carrier Proteins; Cladribine; Cloning, Molecular; Cytarabine; Databases, Factual; DNA, Complementary; Equilibrative Nucleoside Transporter 1; Humans; Membrane Proteins; Molecular Sequence Data; Nucleosides; Oocytes; Recombinant Proteins; Sequence Alignment; Sequence Homology, Amino Acid; Tissue Distribution; Uridine; Vidarabine; Xenopus | 1997 |
Synthesis of phosphonate derivatives of uridine, cytidine, and cytosine arabinoside.
Topics: Antimetabolites, Antineoplastic; Chemistry, Organic; Cytarabine; Cytidine; Organic Chemistry Phenomena; Organophosphonates; Pyruvate Kinase; Uridine | 2000 |
An efficient method for the preparation of 1'alpha-branched-chain sugar pyrimidine ribonucleosides from uridine: the first conversion of a natural nucleoside into 1'-substituted ribonucleosides.
Topics: Cyclization; Cytarabine; Cytidine; Deoxycytidine; Glycosylation; Molecular Structure; Organoselenium Compounds; Pyrimidine Nucleosides; Ribonucleosides; Selenium; Silicon; Stereoisomerism; Structure-Activity Relationship; Uridine; Vinyl Compounds | 2001 |
Mechanisms of uptake and resistance to troxacitabine, a novel deoxycytidine nucleoside analogue, in human leukemic and solid tumor cell lines.
Topics: Amino Acid Sequence; Antineoplastic Agents; Biological Transport; Carrier Proteins; Cytarabine; Cytidine Deaminase; Cytosine; Deoxycytidine; Deoxycytidine Kinase; Dioxolanes; Drug Resistance, Neoplasm; Gemcitabine; Humans; Leukemia; Male; Membrane Proteins; Molecular Sequence Data; Nucleoside Transport Proteins; Phosphorylation; Prostatic Neoplasms; Sequence Homology, Amino Acid; Sodium; Stereoisomerism; Tritium; Tumor Cells, Cultured; Uridine | 2001 |
Synthesis of 5'-amino-5'-phosphonate analogues of pyrimidine nucleoside monophosphates.
Topics: Chromatography, Thin Layer; Cytarabine; Cytidine; Indicators and Reagents; Magnetic Resonance Spectroscopy; Organophosphonates; Oxidation-Reduction; Pyrimidine Nucleosides; Stereoisomerism; Uridine | 2003 |
The role of human nucleoside transporters in cellular uptake of 4'-thio-beta-D-arabinofuranosylcytosine and beta-D-arabinosylcytosine.
Topics: Animals; Arabinonucleosides; Biological Transport; Cell Line, Tumor; Cell Survival; Cytarabine; Cytidine; Dose-Response Relationship, Drug; Equilibrative-Nucleoside Transporter 2; Female; HeLa Cells; Humans; Membrane Potentials; Nucleoside Transport Proteins; Oocytes; Saccharomyces cerevisiae; Thioinosine; Transfection; Tritium; Uridine; Xenopus laevis | 2006 |
Cytidine is a novel substrate for wild-type concentrative nucleoside transporter 2.
Topics: Amino Acid Substitution; Animals; Antimetabolites, Antineoplastic; Biological Transport; Chlorocebus aethiops; COS Cells; Cytarabine; Cytidine; Deoxycytidine; Dose-Response Relationship, Drug; Gemcitabine; Genotype; Kinetics; Male; Membrane Transport Proteins; Mice; Thymidine; Transfection; Tritium; Uridine | 2006 |
Synthesis and antitumor activity of 1-beta-4-selenoarabinofuranosyl cytosine (4'-seleno-ara-C).
Topics: Antineoplastic Agents; Cell Line, Tumor; Cytarabine; Humans; Organoselenium Compounds; Uridine | 2008 |
Superresolution imaging of individual replication forks reveals unexpected prodrug resistance mechanism.
Topics: Animals; Antineoplastic Agents; Azides; Cell Cycle; Cytarabine; DNA; DNA Replication; Humans; Prodrugs; Proliferating Cell Nuclear Antigen; Uridine; Zebrafish | 2018 |