cytarabine and uracil

cytarabine has been researched along with uracil in 36 studies

Research

Studies (36)

TimeframeStudies, this research(%)All Research%
pre-199026 (72.22)18.7374
1990's4 (11.11)18.2507
2000's1 (2.78)29.6817
2010's2 (5.56)24.3611
2020's3 (8.33)2.80

Authors

AuthorsStudies
Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A1
Fox, JJ; Otter, BA1
De Clercq, E; Marquez, VE; Murase, J1
Broder, S; Mitsuya, H; Webb, TR1
Ito, T; Izumi, T; Kurihara, M; Sasaki, J1
Kato, T; Ota, K1
Reidy, JA1
Arai, Y; Endo, T; Kido, C; Ota, K; Suyama, K1
Cihák, A; Veselỳ, J1
el-Dareer, S; Furner, RL; Gaston, RW; Mellett, LB; Strobel, JD1
Hamada, F; Hikita, J; Hirayama, H; Kanai, T; Sugihara, T1
Viola, MV1
Darzynkiewicz, E; Shugar, D1
Dedrick, RL; Forrester, DD; Ho, DH1
Lotem, J; Sachs, L1
Giziewicz, J; Shugar, D1
Cohen, SS1
David, S; Eustache, J1
Goz, B; Prusoff, WH1
Baker, RM; Mankovitz, R; Siminovitch, L; Thompson, LH; Till, JE; Whitmore, GF; Wright, JA1
Renis, HE1
Hyndiuk, RA1
Falco, EA; Fox, JJ1
Ikeda, K; Miura, K; Mizuno, Y; Ueda, T1
Katz, C; Melchionne, S; Sivak, A; Van Duuren, BL1
Notari, RE1
Gehan, EA1
Tschiersch, B1
Furukawa, H; Goto, S; Hiratsuka, M; Iwanaga, T; Kito, T; Nakajima, T; Nakazato, H; Ohta, K; Okabayashi, K; Yamamura, Y1
Azuma, A; Hanaoka, K; Kobayashi, T; Matsuda, A; Minakawa, N; Nakajima, Y; Nishizono, N; Sasaki, T; Suzuki, M; Tanaka, M1
Dan, A; Matsuda, A; Minakawa, N; Okazaki, S; Sasaki, T; Sugimoto, Y; Tregear, SJ1
Cleverley, J1
Andrassy, RJ; Kulkarni, AD; Moore-Olufemi, SD; Shah, SK; Sundaresan, A; Walker, PA1
Feng, Y; He, Z; Hu, B; Li, C; Li, D; Liu, Y; Luo, C; Sun, J; Wang, Q; Zhang, H1
Guosheng, L; Hailei, W; Mengping, Z; Pei, J; Ping, L; Ruxian, J; Zhenyu, W; Zhuoya, L1
Chang, I; Chang, WJ; Chen, R; Circelli, J; Harpel, Z; Rivera, J; Wei, R; Wu, S1

Reviews

4 review(s) available for cytarabine and uracil

ArticleYear
Resistance of mammalian tumour cells toward pyrimidine analogues. A review.
    Oncology, 1973, Volume: 28, Issue:3

    Topics: Animals; Antimetabolites; Azacitidine; Azauridine; Bromouracil; Carcinoma, Ehrlich Tumor; Cell Line; Cricetinae; Cytarabine; Deoxycytidine; Drug Resistance; Fluorouracil; Genetic Code; Leukemia, Experimental; Leukemia, Lymphoid; Mast-Cell Sarcoma; Mice; Mutation; Neoplasms, Experimental; Oncogenic Viruses; Phosphotransferases; Pyrimidines; Sarcoma, Experimental; Selection, Genetic; Thymidine Kinase; Uracil; Virus Replication

1973
Pharmacology of viruses.
    Annual review of pharmacology, 1970, Volume: 10

    Topics: Amantadine; Animals; Antiviral Agents; Chick Embryo; Cytarabine; Fluorouracil; Guanidines; Haplorhini; Humans; Idoxuridine; Interferons; Nucleosides; Receptors, Drug; Rifampin; RNA, Transfer; RNA, Viral; Uracil; Viral Proteins; Virus Diseases; Viruses

1970
[Metabolic modulation as a method in tumor chemotherapy].
    Die Pharmazie, 1982, Volume: 37, Issue:7

    Topics: Antineoplastic Agents; Cytarabine; Fluorouracil; Humans; Methotrexate; Neoplasms; Tegafur; Thymidine; Uracil

1982
An evidence-based review of a Lentinula edodes mushroom extract as complementary therapy in the surgical oncology patient.
    JPEN. Journal of parenteral and enteral nutrition, 2011, Volume: 35, Issue:4

    Topics: Animals; Anti-Bacterial Agents; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Antiviral Agents; Bacterial Infections; Biological Products; China; Cisplatin; Cytarabine; Dexamethasone; Evidence-Based Medicine; Humans; Immunosuppression Therapy; Japan; Neoplasms; Polysaccharides; Randomized Controlled Trials as Topic; Shiitake Mushrooms; Tegafur; United States; Uracil; Virus Diseases

2011

Trials

1 trial(s) available for cytarabine and uracil

ArticleYear
Randomized study with mitomycin C + 5-fluorouracil+cytosine arabinoside (MFC)+5-fluorouracil, MFC+tegafur and uracil (UFT), and MF+UFT in advanced gastric cancer: interinstitutional differences in a multicenter study in Japan.
    Journal of surgical oncology, 1995, Volume: 60, Issue:1

    Topics: Administration, Oral; Aged; Antineoplastic Combined Chemotherapy Protocols; Chemotherapy, Adjuvant; Cytarabine; Drug Administration Schedule; Female; Fluorouracil; Gastrectomy; Humans; Japan; Male; Middle Aged; Mitomycin; Stomach Neoplasms; Survival Rate; Tegafur; Uracil

1995

Other Studies

31 other study(ies) available for cytarabine and uracil

ArticleYear
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
    Chemical research in toxicology, 2010, Volume: 23, Issue:1

    Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship

2010
Nucleosides. XCI. Some chemical properties of the antileukemic agent 2,2'-anhydro-1-beta-D-arabinofuranosyl-5-fluorocytosine.
    Annals of the New York Academy of Sciences, 1975, Aug-08, Volume: 255

    Topics: Animals; Antineoplastic Agents; Biological Assay; Chemical Phenomena; Chemistry; Cytarabine; Flucytosine; Hydrolysis; Kinetics; Male; Rats; Spectrophotometry, Ultraviolet; Structure-Activity Relationship; Uracil

1975
Broad-spectrum antiviral and cytocidal activity of cyclopentenylcytosine, a carbocyclic nucleoside targeted at CTP synthetase.
    Biochemical pharmacology, 1991, Jun-15, Volume: 41, Issue:12

    Topics: Adenosine; Amides; Antiviral Agents; Azauridine; Carbon-Nitrogen Ligases; Cell Division; Cytarabine; Cytidine; Deoxycytidine; Drug Synergism; Fluorouracil; HeLa Cells; Humans; Ligases; Nucleosides; Pyrazoles; Ribavirin; Ribonucleosides; Ribose; Thymidine; Tumor Cells, Cultured; Uracil; Virus Replication; Viruses

1991
1-(2,3-Anhydro-beta-D-lyxofuranosyl)cytosine derivatives as potential inhibitors of the human immunodeficiency virus.
    Journal of medicinal chemistry, 1988, Volume: 31, Issue:7

    Topics: Ancitabine; Chemical Phenomena; Chemistry; Cytarabine; Cytidine; HIV; Magnetic Resonance Spectroscopy; Mass Spectrometry; Thymidine; Uracil; Zidovudine

1988
[Cancer chemotherapy of scirrhous type gastric cancer and evaluation of chemotherapeutic efficacy].
    Gan to kagaku ryoho. Cancer & chemotherapy, 1988, Volume: 15, Issue:4 Pt 2-2

    Topics: Adenocarcinoma, Scirrhous; Administration, Oral; Antineoplastic Combined Chemotherapy Protocols; Cytarabine; Fluorouracil; Humans; Injections, Intravenous; Mitomycin; Mitomycins; Radiography; Stomach Neoplasms; Tegafur; Uracil

1988
[Effects of derivatives of Ara-C, 5-fluorouracil and nitrosourea against intracerebral implanted L1210 leukemia].
    Gan to kagaku ryoho. Cancer & chemotherapy, 1987, Volume: 14, Issue:2

    Topics: Animals; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Blood-Brain Barrier; Brain Neoplasms; Cytarabine; Fluorouracil; Leukemia L1210; Mice; Neoplasm Transplantation; Nimustine; Nitrosourea Compounds; Streptozocin; Tegafur; Uracil

1987
Folate- and deoxyuridine-sensitive chromatid breakage may result from DNA repair during G2.
    Mutation research, 1987, Volume: 192, Issue:3

    Topics: Aphidicolin; Chromosome Aberrations; Chromosome Fragility; Cytarabine; Deoxyuridine; Diterpenes; DNA Repair; Folic Acid; Humans; In Vitro Techniques; Interphase; Lymphocytes; Uracil

1987
[Intra-arterial infusion chemotherapy using a subcutaneously implanted silicone reservoir--with reference to the chemotherapy protocol].
    Gan to kagaku ryoho. Cancer & chemotherapy, 1985, Volume: 12, Issue:2

    Topics: Abdominal Neoplasms; Aged; Antineoplastic Combined Chemotherapy Protocols; Catheterization; Cytarabine; Female; Fluorouracil; Humans; Infusions, Intra-Arterial; Liver Neoplasms; Male; Middle Aged; Mitomycin; Mitomycins; Silicone Elastomers; Stomach Neoplasms; Tegafur; Uracil

1985
Differential analysis of cyclocytidine, 1-beta-D-arabinofuranosylcytosine, and 1-beta-D-arabinofuranosyluracil by ultraviolet spectophotometry.
    Journal of the National Cancer Institute, 1974, Volume: 52, Issue:5

    Topics: Anhydrides; Animals; Arabinose; Bone Marrow; Cytarabine; Dogs; Haplorhini; Humans; Hydrochloric Acid; Methods; Mice; Nucleosides; Rats; Spectrophotometry, Ultraviolet; Uracil

1974
Distribution and excretion of cyclocytidine in monkeys, dogs, and rats.
    Gan, 1974, Volume: 65, Issue:2

    Topics: Anhydrides; Animals; Arabinose; Cytarabine; Cytidine; Dogs; Feces; Half-Life; Haplorhini; Injections, Intravenous; Kidney; Liver; Macaca; Nucleosides; Rats; Uracil

1974
Acute leukemia and infection.
    JAMA, 1967, Sep-18, Volume: 201, Issue:12

    Topics: Acute Disease; Adolescent; Adrenocorticotropic Hormone; Adult; Aged; Agranulocytosis; Aspergillosis; Candidiasis; Cytarabine; Female; Humans; Leukemia; Male; Mercaptopurine; Methotrexate; Middle Aged; Mucormycosis; Nocardia Infections; Prednisone; Proteus Infections; Pseudomonas Infections; Sepsis; Staphylococcal Infections; Strongyloidiasis; Uracil; Vinblastine

1967
Preparation and properties of O'-methyl and O'-ethyl derivatives of 1-beta-D-arabinofuranosylcytosine and 1-beta-D-arabinofuranosyluracil.
    Acta biochimica Polonica, 1974, Volume: 21, Issue:3

    Topics: Alkylation; Chromatography, Paper; Cytarabine; Deamination; Ethyl Ethers; Methyl Ethers; Methylation; Molecular Conformation; Nucleosides; Spectrophotometry, Ultraviolet; Uracil

1974
In vitro-in vivo correlation of drug metabolism--deamination of 1- -D-arabinofuranosylcytosine.
    Biochemical pharmacology, 1972, Volume: 21, Issue:1

    Topics: Aminohydrolases; Carbon Isotopes; Cytarabine; Deamination; Female; Humans; Kinetics; Leukemia, Myeloid; Lymphoma; Male; Mathematics; Models, Biological; Uracil

1972
Different blocks in the differentiation of myeloid leukemic cells.
    Proceedings of the National Academy of Sciences of the United States of America, 1974, Volume: 71, Issue:9

    Topics: Animals; Binding Sites, Antibody; Blood; Cell Differentiation; Cell Membrane; Cells, Cultured; Complement System Proteins; Cytarabine; Dactinomycin; Endotoxins; Erythrocytes; Granulocytes; Immune Adherence Reaction; Immunoglobulins; Leukemia, Experimental; Leukemia, Myeloid; Leukocytes; Macrophages; Mice; Prednisolone; Sheep; Uracil

1974
Direct synthesis of the 2'-O-methyl analogues of 1- -(D-arabinofuranosyl) cytosine and uracil and some related derivatives.
    Acta biochimica Polonica, 1973, Volume: 20, Issue:1

    Topics: Chromatography; Cytarabine; Methylation; Uracil

1973
Sponges, cancer chemotherapy, and cellular aging.
    Perspectives in biology and medicine, 1963,Winter, Volume: 6, Issue:2

    Topics: Bacteriological Techniques; Cytarabine; DNA; Escherichia coli; Neoplasms; Nucleosides; Phosphates; Porifera; Protein Biosynthesis; Ribose; RNA; Uracil

1963
[Stereospecificity of ribonucleoside diphosphate reductase: preparation of deuterated pyrimidine deoxyribonucleosides].
    Carbohydrate research, 1971, Volume: 20, Issue:2

    Topics: Cytarabine; Cytosine Nucleotides; Deoxyribonucleosides; Deoxyuridine; Deuterium; Escherichia coli; Magnetic Resonance Spectroscopy; Methanol; Nucleosides; Oxidoreductases; Ribonucleotides; Stereoisomerism; Uracil

1971
Selective and nonselective isolation of temperature-sensitive mutants of mouse L-cells and their characterization.
    Journal of cellular physiology, 1971, Volume: 78, Issue:3

    Topics: Animals; Cell Survival; Clone Cells; Cytarabine; Cytosine; L Cells; Leucine; Methods; Mice; Mutation; Nitrosoguanidines; Phenotype; Selection, Genetic; Temperature; Thymidine; Time Factors; Tritium; Uracil

1971
Comparison of cytotoxicity and antiviral activity of 1-beta-D-arabino-furanosyl-5-iodocytosine with related compounds.
    Cancer research, 1970, Volume: 30, Issue:1

    Topics: Animals; Antiviral Agents; Culture Techniques; Cytarabine; Cytosine Nucleotides; Deoxyuridine; DNA Viruses; Herpesviridae; Iodine; Kidney; Nucleosides; Rabbits; Thymidine; Uracil; Vaccinia virus; Virus Replication

1970
Medical and surgical management of viral keratitis.
    Wisconsin medical journal, 1971, Volume: 70, Issue:5

    Topics: Adenine; Arabinose; Cytarabine; Humans; Keratitis, Dendritic; Nucleosides; Rifampin; Uracil

1971
Nucleosides. 48. Synthesis of 1-(5-deoxy-beta-D-arabinosyl)cytosine and related compounds.
    Journal of medicinal chemistry, 1968, Volume: 11, Issue:1

    Topics: Animals; Burkitt Lymphoma; Carbonates; Cytarabine; Humans; Leukemia L1210; Methods; Mice; Nucleosides; Sulfur; Thiouracil; Uracil

1968
Synthetic studies of potential antimetabolites. XI. Syntheses of beta-D-pentofuranosyl-5-methylcytosines.
    Chemical & pharmaceutical bulletin, 1968, Volume: 16, Issue:2

    Topics: Cytarabine; Cytosine; Pyrimidines; Thiamine; Uracil

1968
Inhibition of tumor induction in two-stage carcinogenesis on mouse skin.
    Cancer research, 1969, Volume: 29, Issue:4

    Topics: Aflatoxins; Animals; Antineoplastic Agents; Benz(a)Anthracenes; Chloroquine; Cyclohexanes; Cytarabine; Dactinomycin; Ethers, Cyclic; Female; Mice; Neoplasms, Experimental; Skin Neoplasms; Uracil

1969
A mechanism for the hydrolytic deamination of cytosine arabinoside in aqueous buffer.
    Journal of pharmaceutical sciences, 1967, Volume: 56, Issue:7

    Topics: Buffers; Chromatography, Thin Layer; Cytarabine; Hydrogen; Hydrogen-Ion Concentration; Kinetics; Sodium; Sulfites; Temperature; Ultraviolet Rays; Uracil

1967
Design of controlled clinical trials: use of historical controls.
    Cancer treatment reports, 1982, Volume: 66, Issue:5

    Topics: Acute Disease; Adolescent; Adult; Clinical Trials as Topic; Cyclophosphamide; Cytarabine; Daunorubicin; Drug Therapy, Combination; Female; Glioma; Humans; Leukemia; Male; Plicamycin; Random Allocation; Uracil; Vincristine

1982
Nucleosides and nucleotides. 122. 2'-C-cyano-2'-deoxy-1-beta-D-arabinofuranosylcytosine and its derivatives. A new class of nucleoside with a broad antitumor spectrum.
    Journal of medicinal chemistry, 1993, Dec-24, Volume: 36, Issue:26

    Topics: Adenine; Animals; Antineoplastic Agents; Cytarabine; Female; Fluorouracil; Humans; Leukemia L1210; Lymphoma, Large B-Cell, Diffuse; Mice; Molecular Structure; Neoplasm Transplantation; Structure-Activity Relationship; Thymine; Tumor Cells, Cultured; Uracil

1993
Nucleosides and nucleotides. 123. Synthesis of 1-(2-deoxy-2-isocyano-beta-D-arabinofuranosyl)cytosine and related nucleosides as potential antitumor agents.
    Journal of medicinal chemistry, 1993, Dec-24, Volume: 36, Issue:26

    Topics: Animals; Antineoplastic Agents; Cytarabine; Deoxycytidine; Drug Stability; Humans; Isocyanates; Leukemia L1210; Lung Neoplasms; Mice; Molecular Structure; Mouth Neoplasms; Stomach Neoplasms; Thymine; Tumor Cells, Cultured; Uracil

1993
American Society of Clinical Oncology--42nd annual meeting. Poster presentations on leukemia and cytotoxic chemotherapy. 2-6 June 2006, Atlanta, GA, USA.
    IDrugs : the investigational drugs journal, 2006, Volume: 9, Issue:8

    Topics: Clinical Trials as Topic; Cytarabine; Drug Combinations; Gossypol; Humans; Leukemia; Mastocytosis, Systemic; Molecular Structure; Pyrimidines; Pyrrolidines; Thionucleotides; Thymine; Trifluridine; Uracil

2006
Molecular recognition-driven supramolecular nanoassembly of a hydrophobic uracil prodrug and hydrophilic cytarabine for precise combination treatment of solid and non-solid tumors.
    Nanoscale horizons, 2022, 01-31, Volume: 7, Issue:2

    Topics: Cell Line, Tumor; Cytarabine; Hydrophobic and Hydrophilic Interactions; Prodrugs; Uracil

2022
Whole-cell biosynthesis of cytarabine by an unnecessary protein-reduced Escherichia coli that coexpresses purine and uracil phosphorylase.
    Biotechnology and bioengineering, 2022, Volume: 119, Issue:7

    Topics: Cytarabine; Escherichia coli; Phosphorylases; Purine-Nucleoside Phosphorylase; Purines; Uracil

2022
Effects of six pyrimidine analogs on the growth of Tetrahymena thermophila and their implications in pyrimidine metabolism.
    PloS one, 2023, Volume: 18, Issue:9

    Topics: Antimetabolites; Cytarabine; Floxuridine; Fluorouracil; Gemcitabine; Nucleosides; Pyrimidines; Tetrahymena thermophila; Thymine; Uracil

2023