cytarabine has been researched along with tretinoin in 342 studies
Timeframe | Studies, this research(%) | All Research% |
---|---|---|
pre-1990 | 34 (9.94) | 18.7374 |
1990's | 122 (35.67) | 18.2507 |
2000's | 109 (31.87) | 29.6817 |
2010's | 67 (19.59) | 24.3611 |
2020's | 10 (2.92) | 2.80 |
Authors | Studies |
---|---|
Balzarini, J; Bazzanini, R; De Clercq, E; Ferroni, R; Hatse, S; Manfredini, S; Simoni, D; Vertuani, S | 1 |
Benz, RD; Contrera, JF; Kruhlak, NL; Matthews, EJ; Weaver, JL | 1 |
Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A | 1 |
Ambroso, JL; Ayrton, AD; Baines, IA; Bloomer, JC; Chen, L; Clarke, SE; Ellens, HM; Harrell, AW; Lovatt, CA; Reese, MJ; Sakatis, MZ; Taylor, MA; Yang, EY | 1 |
Afshari, CA; Chen, Y; Dunn, RT; Hamadeh, HK; Kalanzi, J; Kalyanaraman, N; Morgan, RE; van Staden, CJ | 1 |
Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K | 1 |
Agnish, ND; Kochhar, DM | 1 |
Aller, P; Rius, C | 1 |
Cornaglia-Ferraris, P; Folghera, S; Lanciotti, M; Lucarelli, E; Montaldo, PG; Ponzoni, M | 1 |
Archimbaud, E; Castaigne, S; Dombret, H; Duarte, M; Fenaux, P; Guerci, A; Lamy, T; Maloisel, F; Morel, P; Tilly, H | 1 |
Curtis, JE; Lipton, JH; Lockwood, GA; McCulloch, EA; Messner, HA; Minden, MD; Tritchler, DL | 1 |
De Laurenzi, A; De Rosa, L; Montuoro, A | 1 |
Elliott, S; Marlton, P; Meagher, D; Rodwell, R; Taylor, D; Taylor, K; Timms, P; White, S; Wiley, J; Wright, S | 1 |
Berman, E | 1 |
Curtis, JE; McCulloch, EA; Minden, MD; Tohda, S | 1 |
Banavali, SD; Bokari, SA; Finke, D; Gopal, V; Preisler, HD | 1 |
Koistinen, P; Lyman, SD; McCulloch, EA; Minden, MD; Wang, C; Wang, YF; Williams, DE; Yang, GS | 1 |
Cornaglia-Ferraris, P; Lanciotti, M; Montaldo, PG; Ponzoni, M | 1 |
Wiernik, PH | 1 |
Hassan, HT; Ragab, MH; Rees, JK; Zyada, LE | 1 |
Costello, C; McCarthy, D; Mir, N; Nadir, F; Rule, S; Samson, D; Taylor, J | 1 |
Baltimore, D; Chun, JJ; Jaenisch, R; Oettinger, MA; Schatz, DG | 1 |
de Vellis, J; Sidell, N; Wuarin, L | 1 |
Degos, L | 2 |
Billström, R; Carneskog, J; Grimfors, G; Hellström, E; Kimby, E; Lindemalm, C; Oberg, G; Robèrt, KH; Samuelsson, J; Winqvist, I | 1 |
Hassan, HT; Rees, JK | 1 |
Akiyama, Y; Kitoh, T; Kubota, M; Mikawa, H; Takimoto, T; Tanizawa, A; Tsuruta, S | 1 |
Huijgens, PC; Langenhuijsen, MM; Nauta, JJ; Ossenkoppele, GJ; Wijermans, PW | 1 |
Mejer, J; Mortensen, BT | 1 |
Akiyama, Y; Kiriyama, Y; Kitoh, T; Kubota, M; Mikawa, H; Takimoto, T; Tanizawa, A | 1 |
Gahrton, G; Hellström, E; Ost, A; Putkonen, PO; Robèrt, KH; Soppi, E | 1 |
Curtis, JE; Lishner, M; McCulloch, EA; Minkin, S | 1 |
Appelbaum, FR; Hoffman, R; Jansen, J; Lauer, RC; Tricot, GJ | 1 |
Layton, DM; Mufti, GJ; Pagliuca, A | 1 |
Koenderman, AH; van den Eijnden, DH; Wijermans, PW | 1 |
Ahlstedt, S; Akerblom, E; Almlöf, I; Johansson, V; Matsson, P; Nilsson, K; Slotte, H | 1 |
Einhorn, S; Gahrton, G; Hellström, E; Robèrt, KH | 1 |
Andrews, PW; Dignazio, M; Gönczöl, E; Oosterhuis, JW; Plotkin, SA | 1 |
Firkin, FC; Januszewicz, EH | 1 |
Cai, JR; Chen, SR; Gu, LJ; Huang, ME; Shen, ZX; Wang, ZY; Xie, JX; Ye, YC; Zhao, JC; Zhao, L | 1 |
Pályi, I | 1 |
Clark, RE; Ismail, SA; Jacobs, A; Payne, H; Smith, SA | 1 |
Ho, AD; Hunstein, W; Knauf, W; Martin, H; Reichardt, P; Trümper, L | 1 |
Björkholm, M; Einhorn, S; Gahrton, G; Grimfors, G; Hellström, E; Lindemalm, C; Mellstedt, H; Robèrt, KH; Samuelsson, J; Udén, AM | 1 |
Durham, JP; Fontana, JA; Rogers, JS | 1 |
Abita, JP; Balitrand, N; Chomienne, C; Degos, L | 2 |
Huang, ME; Ye, YC; Zhao, L | 1 |
Berney, JJ; Francis, GE; Guimaraes, JE; Hamblin, TJ; Knowles, SM; Mufti, GJ; Secker-Walker, LM | 1 |
Boogaerts, MA; Tricot, G; Verwilghen, RL | 1 |
Ishikura, H; Izumi, Y; Mochizuki, T; Okazaki, T; Sawada, H; Tashima, M; Uchino, H | 2 |
Buzaid, AC; Garewal, HS; Greenberg, BR | 1 |
Kufe, D; Mitchell, T; Sariban, E | 1 |
Arlin, ZA; Berman, E; Chaganti, RS; Clarkson, BD; Gee, T; Jhanwar, SC; Kurland, E; Mertelsmann, R; Moore, MA | 1 |
Berens, ME; Cogoli, M; Früh, U; Hofmann, V; Kistler, G; Merchant, RE; Moreillon, MC | 1 |
Berney, JJ; Francis, GE; Guimaraes, JE; Wing, MA | 2 |
Bloch, A; Craig, RW; Frankfurt, OS; Sakagami, H; Takeda, K | 1 |
Endo, K; Ichinohasama, R; Imaizumi, M; Inoue, S; Koizumi, Y; Sato, A; Sawai, T; Suwabe, N; Suzuki, H; Yoshinari, M | 1 |
Bassini, A; Celeghini, C; Gibellini, D; Manfroi, S; Ottaviani, E; Pagliarini, C; Tosi, P; Tura, S; Visani, G; Zauli, G | 1 |
Hu, ZB; McCulloch, EA; Minden, MD | 2 |
Aronica, G; Bruno, A; Buccisano, F; Caravita, T; Del Poeta, G; Masi, M; Pisani, F; Stasi, R; Tribalto, M; Venditti, A | 1 |
Scheinberg, DA | 1 |
McCulloch, EA; Minden, MD; Yang, GS | 2 |
Han, R; Li, L; Xia, L | 1 |
Gunning, K; Harman, K; Mahendra, P; Marcus, RE; Phillips, M | 1 |
Bauduer, F; Cymbalista, F; Delmer, A; Fenaux, P; Marie, JP; Martin, A; Rio, B; Zittoun, R | 1 |
Hu, ZB; Li, M; McCulloch, EA; Minden, MD; Miyamoto, N; Yang, GS | 1 |
Archim-Baud, E; Castaigne, S; Chastang, C; Chomienne, C; Degos, L; Fenaux, P; Fey, M; Link, H; Löwenberg, B; Sanz, M | 1 |
McCulloch, EA; Minden, MD; Wang, C; Yang, GS | 1 |
Fenaux, P | 1 |
Ohno, R | 2 |
Asou, N; Kanamaru, A; Kobayashi, T; Kuriyama, K; Murakami, H; Ohmoto, E; Sakamaki, H; Takemoto, Y; Tanimoto, M; Tsubaki, K | 1 |
D'Onofrio, G; Di Mario, A; Etuk, B; Leone, G; Salutari, P; Sica, S | 1 |
Cenacchi, A; Gamberi, B; Manfroi, S; Ottaviani, E; Tosi, P; Tura, S; Visani, G | 1 |
Caron, PC; Finn, RD; Jurcic, JG; Larson, SM; Maslak, P; Miller, WH; Scheinberg, DA; Warrell, RP; Yao, TJ | 1 |
Gadner, H; Krieger, O; Schmitt, K; Schwarz, R; Tulzer, G; Zoubek, A | 1 |
Chastang, C; Chomienne, C; Degos, L; Fenaux, P | 1 |
Chen, A; Hellinger, N; Licht, JD; Scher, W; Waxman, S; Wu, Y | 1 |
Arbona, C; Benet, I; Carbonell, F; Escrig, V; García Conde, J; García Marco, J; Miguel García, A; Miguel Sosa, A; Navarro, I; Ruiz, A | 1 |
Chen, SJ; Gu, YZ; Huang, LA; Lu, JX; Ouyang, RR; Sun, GL; Wang, ZY | 1 |
Haase, D; Hehlmann, R; Hild, F; Lengfelder, E; Simon, M | 1 |
Tsukagoshi, S | 1 |
MacCabe, JA | 1 |
Ikeda, Y; Iki, S; Ohbayashi, Y; Urabe, A; Yoshinaga, K | 1 |
Griggs, JJ; Henley, SE; Rowe, JM | 1 |
Bianchi-Scarrá, G; Cutrona, G; Fiorentini, P; Garré, C; Musso, M; Pistoia, V; Zarcone, D | 1 |
Eardley, AM; Heller, G; Warrell, RP | 1 |
He, HT; Wang, XT | 1 |
Haas, OA; Kapiotis, S; Knöbl, P; Korninger, L; Kyrle, PA; Laczika, K; Mitterbauer, G; Oehler, L; Pont, J; Schwarzinger, I | 1 |
Gassmann, W; Glass, B; Haferlach, T; Löffler, H | 1 |
Park, M; Yang, XM | 1 |
Aller, P; Mata, F; Rius, C; Vilaboa, N | 1 |
Bruno, A; Coppetelli, U; Cox, C; Del Poeta, G; Franchi, A; Masi, M; Piccioni, D; Stasi, R; Tribalto, M; Venditti, A | 1 |
Lefebvre, PP; Malgrange, B; Moonen, G; Staecker, H; Van de Water, TR | 1 |
Arborio, M; De Revel, T; Desangles, F; Flandrin, G; Vilain, E | 1 |
Garcés-Eisele, J; Ruiz-Argüelles, A; Ruiz-Argüelles, GJ | 1 |
Gadner, H; Koller, E; Krieger, O; Lutz, D; Schmitt, K; Schwarz, R; Tulzer, G; Zoubek, A | 1 |
Catalano, L; Frigeri, F; Luciano, L; Notaro, R; Pane, F; Rotoli, B; Salvatore, F; Santoro, LE; Selleri, C | 1 |
Hoffman, MA; Kleiner, GJ; Wiernik, PH | 1 |
Asou, H; Awaya, N; Ikeda, Y; Kamada, N; Kawai, Y; Kizaki, M; Matsushita, H; Muto, A; Takayama, N; Ueno, H | 1 |
Escudier, SM; Estey, EH; Kantarjian, HM | 1 |
Kakihara, T; Kataoka, S; Kishi, K; Okada, R; Tanaka, A; Uchiyama, M; Watanabe, A; Yamamoto, K | 1 |
Curtis, JE; McCulloch, EA; Minden, MD; Minkin, S | 1 |
Chomienne, C; Degos, L; Fenaux, P | 1 |
Madarász, E; Schlett, K | 1 |
Chan, CH; Chan, LC; Chan, TK; Chim, CS; Chu, YC; Kwong, YL; Liang, R; Wong, KF | 1 |
Adle-Biassette, H; Authier, FJ; Chomienne, C; Defer, GL; Degos, JD; Degos, L; Martin, L; Ricolfi, F | 1 |
Ohnishi, K; Ohno, R; Shinjyo, K; Takeshita, A; Tobita, T; Yanagi, M | 1 |
Hiraoka, A; Karasuno, T; Kitamura, K; Miyawaki, S; Naoe, T; Ohnishi, K; Ohno, R; Takeshita, A; Takeuchi, M; Tobita, T; Ueda, R; Yanagi, M | 1 |
Avvisati, G; Capria, S; Diverio, D; Lo Coco, F; Mandelli, F; Meloni, G; Petti, MC; Vignetti, M | 1 |
Fujimoto, T; Hirota, T; Horikoshi, Y; Kamitamari, A; Katano, N; Kawamura, N; Mimaya, J; Tsuji, Y; Tsurusawa, M; Yanai, M | 1 |
Harano, H; Kanamori, H; Matsuzaki, M; Mohri, H; Ogawa, K; Okubo, C; Okubo, T; Otsuka, M; Sasaki, S; Taguchi, J | 1 |
Budhiraja, S; Jacob, A; Reichel, RR | 1 |
Honma, Y; Niitsu, N; Umeda, M | 1 |
Andersen, JW; Appelbaum, FR; Bloomfield, CD; Feusner, JH; Ogden, A; Rowe, JM; Schiffer, CA; Shepherd, L; Tallman, MS; Wiernik, PH; Willman, C | 1 |
Babić, D; Bila, JS; Colović, MD; Elezović, I; Janković, GM; Novak, A; Vidović, A | 1 |
Mandelli, F | 1 |
Honma, Y; Kanatani, Y; Matsuda, A; Niitsu, N; Shuto, S; Umeda, M; Yamamoto-Yamaguchi, Y | 1 |
Asami, K; Eguchi, H; Fujimoto, T; Gushiken, T; Hirota, T; Hyakuna, N; Imaizumi, M; Kamitamari, A; Katano, N; Kawakami, K; Koizumi, S; Komatu, K; Miyake, M; Mugishima, H; Nakadate, N; Nishikawa, K; Shirahata, A; Takitani, K; Tsurasawa, M; Yanase, T | 1 |
Adachi, K; Akiyama, H; Asou, N; Emi, N; Hiraoka, A; Kageyama, S; Kanamaru, A; Kitano, K; Kuriyama, K; Matsuda, S; Miyawaki, S; Nishikawa, K; Oh, H; Ohno, R; Ohtake, S; Omoto, E; Saito, K; Suzushima, H; Takahashi, M; Takeyama, K; Tamura, J; Tsubaki, K; Yamada, O | 1 |
Eto, T; Hayashi, S; Nagafuji, K; Niho, Y; Tokunaga, Y | 1 |
Bowen, DT; Burnett, AK; Darley, RL; Gallagher, AP | 1 |
Advani, SH; Nair, CN; Nair, R | 1 |
Carrera, I; Ding, W; Gallagher, RE; Grills, G; Li, YP; Nobile, LM; Paietta, E; Tallman, MS; Wiernik, PH | 1 |
Archimbaud, E; Fiere, D; Thomas, X | 1 |
Asai, O; Dobashi, N; Kato, A; Katori, M; Kobayashi, T; Kuraishi, Y; Maki, N; Nagamine, M; Ogihara, A; Saito, T; Tajima, N; Usui, N; Watanabe, H; Yamazaki, H; Yano, S | 1 |
Caillot, D; Chastang, C; Chomienne, C; Condé, E; De Botton, S; de la Serna, J; Degos, L; Dombret, H; Fenaux, P; Gardembas, M; Gardin, C; Geiser, K; Guerci, A; Lefrere, F; Makhoul, DC; Miguel, JS; Reman, O; Sanz, M; Stamatoulas, A; Zittoun, R | 1 |
Han, J; Sun, G; Zhao, J | 1 |
Biondi, A; Coppi, MR; Liso, V; Mestice, A; Mininni, D; Palumbo, G; Pogliani, EM; Rossi, V; Specchia, G; Teruzzi, E | 1 |
Bernasconi, C; Castagnola, C; Corso, A; Dabusti, M; Lazzarino, M; Lunghi, M; Tajana, M; Zappasodi, P | 1 |
Cortesi, R; Gambari, R; Gui, V; Nastruzzi, C; Osti, F | 1 |
Harada, M; Kibata, M; Ohno, R; Omoto, E; Shudo, K; Takahashi, K; Takeuchi, M; Ueda, R; Yano, T | 1 |
Advani, SH; Bapna, A; Gladstone, B; Gopal, R; Kadam, P; Nair, CN; Nair, R; Parekh, PM; Saikia, TK | 1 |
Funkhouser, TA; Vik, DP | 1 |
Bigas, A; Chernukhin, IV; Delgado, MD; Klenova, EM; León, J | 1 |
Ohnishi, K | 1 |
Janckila, A; Varghese, L; Yam, LT | 1 |
Chillón, C; García, JL; González, M; Gutiérrez, NC; Hernández, JM; Muntión, S | 1 |
Bertone, A; Marin, L; Martinelli, G; Russo, D; Testoni, N; Tiribelli, M | 1 |
Andreeff, M; Beran, M; Cortes, J; Estey, EH; Freireich, E; Kantarjian, H; Keating, MJ; Pierce, S; Thall, PF | 1 |
Mollee, PN; Rodwell, R; Taylor, D; Taylor, KM; Williams, B | 1 |
Boos, J; Freund, A; Gescher, A; Hohenlöchter, B; Jürgens, H; Lanvers, C; Rössig, C | 1 |
Bernardo, M; Conduto, A; Costa, I; Cruz, E; Fernandes, JP; Ferreira, G; Gonçalves, AJ; Gouveia, J; Monteiro, A; Nunes, O; Ribeiro, P; Rodrigues, AS; Sousa, AB; Sousa, M; Veiga, J | 1 |
Ahmed, N; Baumforth, KR; Hassan, HT; Laverick, L; Sammons, J | 1 |
Cortesi, R; Gambari, R; Gui, V; Nastruzzi, C | 1 |
Letendre, L; Li, CY; Litzow, MR; Noel, P; Schroeder, G; Tefferi, A; White, WL | 1 |
Demidova, IA; Galstian, GM; Isaev, VG; Kliasova, GA; Ol'shanskaia, IuV; Parovichnikova, EN; Pivnik, AV; Savchenko, VG; Tikhonova, LIu; Tiurina, NG | 1 |
Avvisati, G; Biondi, A; Carlo-Stella, C; Diverio, D; Lo Coco, F; Mandelli, F; Martino, B; Meloni, G; Petti, MC; Pogliani, EM; Rossi, G; Selleri, C; Specchia, G | 1 |
Filipits, M; Geissler, K; Jäger, U; Lechner, K; Pirker, R; Pohl, G; Scheper, RJ; Stranzl, T; Suchomel, RW | 1 |
Andreeff, M; Champlin, RC; Dong, J; Estey, EH; Estrov, Z; Jiang, S; Konopleva, M; Kornblau, SM; Okcu, MF; Reed, JC; Sanchez-Williams, G; Snell, VE; Xie, Z; Zhang, X; Zhao, S | 1 |
Bergonzi, MC; Bianchi, N; Catelani, G; D'Andrea, F; Gambari, R; Osti, F | 1 |
Alaejos, I; Arbeteta, J; Balanzategui, A; Chillón, MC; García-Sanz, R; González, D; González, M; Hernández, JM; López-Pérez, R; Mateos, MV; Orfao, A; Rayón, C; San Miguel, J | 1 |
Iwata, N; Kawahigashi, N; Kobayashi, Y; Maeda, A; Saito, T; Takaue, Y; Takenaka, T; Tanosaki, R; Tobinai, K; Togitani, K | 1 |
Andersen, JW; Appelbaum, FR; Feusner, JH; François, C; Larson, RS; Ogden, A; Rowe, JM; Schiffer, CA; Shepherd, L; Tallman, MS; Wiernik, PH | 1 |
Cortes, J; Freireich, EJ; Gajewski, J; Giles, FJ; Kantarjian, HM; Koller, C; Kornblau, S; O'Brien, S; Rios, MB; Sacchi, S; Talpaz, M | 1 |
Chan, FS; Ip, NY; Leung, MF; Xie, P | 1 |
Andersen, JW; Bloomfield, CD; Gallagher, RE; Li, YP; Slack, JL; Tallman, MS; Viswanatha, DS; Willman, CL | 1 |
Minamikawa, K; Nakase, K; Shiku, H; Wakita, Y; Yamaguchi, T | 1 |
Hu, ZB; McCulloch, EA; Minden, MD; Stahl, J | 1 |
Ahmed, T; Burke, HB; Darzynkiewicz, Z; Deptala, A; Dorota Halicka, H; Feldman, EJ; Goff, H; Hoang, A; Kancherla, R; Pozzuoli, M; Seiter, K; Traganos, F | 1 |
Ohno, R; Takeshita, A | 1 |
Haas, OA; Jaeger, U; Knöbl, P; Laczika, K; Lechner, K; Mitterbauer, G; Thalhammer-Scherrer, R; Weltermann, A | 1 |
Abruzzese, E; Amadori, S; Buccisano, F; Cox, MC; Del Poeta, G; Masi, M; Maurillo, L; Scimò, MT; Tamburini, A; Tribalto, M; Venditti, A | 1 |
Ahmed, T; Baskind, P; Darzynkiewicz, Z; Feldman, EJ; Goff, H; Pozzuoli, M; Santos, S; Seiter, K; Traganos, F | 1 |
Kuriyama, K | 1 |
Ezaki, K; Hasegawa, A; Hirano, M; Ino, T; Kojima, H; Maruyama, F; Matsui, T; Miyazaki, H; Okamoto, M; Tsuzuki, M | 1 |
Berthou, C; Buzyn, A; Cahn, JY; Chomienne, C; Cordonnier, C; de Revel, T; Degos, L; Dombret, H; Fegueux, N; Fenaux, P; Gardin, C; Gratecos, N; Guerci, A; Huguet, F; Kotoucek, P; Maloisel, F; Naccache, P; Pigneux, A; Reman, O; Sadoun, A; Stamatoullas, A; Thomas, X; Travade, P; Vekhoff, A; Vilque, JP | 1 |
Boros, B; Egyed, M; Földi, J; Páldi-Haris, P; Rumi, G | 1 |
Avvisati, G; Diverio, D; Lo Coco, F; Mandelli, F | 1 |
Fegan, CD; Hull, DR; Lester, WA; Morris, TC | 1 |
Aul, C; Beelen, D; Büchner, T; Fonatsch, C; Gassmann, W; Haase, D; Haferlach, T; Hehlmann, R; Heinecke, A; Heyll, A; Hiddemann, W; Hochhaus, A; Lengfelder, E; Löffler, H; Ludwig, WD; Reichert, A; Sauerland, MC; Saussele, S; Schoch, C; Seifarth, W; Staib, P; Wörmann, B | 1 |
Davidson, RJ; Goldman, JM; Gordon, MY; Marley, SB | 2 |
Avvisati, G; Barbui, T; Bernasconi, C; Bolufer, P; Colomer, D; Díaz-Mediavilla, J; Esteve, J; Ferrara, F; Fioritoni, G; González, JD; Gonzalez, M; Liso, V; Lo Coco, F; Mandelli, F; Martín, G; Petti, MC; Rayón, C; Ribera, JM; Rodeghiero, F; Sanz, MA | 1 |
Adachi, K; Akiyama, H; Asou, N; Hiraoka, A; Kageyama, S; Kanamaru, A; Ohno, R; Omoto, E; Tamura, J | 1 |
Catani, L; Grafone, T; Gugliotta, L; Isidori, A; Martinelli, G; Nocentini, F; Ottaviani, E; Pastano, R; Piccaluga, P; Testoni, N; Tosi, P; Tura, S; Vianelli, N; Visani, G | 1 |
Avigdor, A; Ben-Bassat, I; Bercowicz, M; Berkenstat, H; Levi, I; Perel, A; Raanani, P; Segal, E | 1 |
Abhyankar, D; Advani, S; Kapoor, B; Menon, H; Nair, R | 1 |
Fukushima, T; Jinnai, I; Kuriyama, K; Matsuo, T; Miyazaki, Y; Moriuchi, Y; Taguchi, J; Tomonaga, M; Yoshida, S | 1 |
Bordessoule, D; Castaigne, S; Chevret, S; Chomienne, C; Cony Makhoul , P; De Botton , S; Deconinck, E; Degos, L; Desablens, B; Dombret, H; Fegueux, N; Fenaux, P; Fey, M; Gardin, C; Geiser, K; Guerci, A; Hess, U; Huguet, F; Link, H; Maloisel, F; Preudhomme, C; Rayon, C; San Miguel , J; Sanz, M; Solary, E; Sotto, JJ; Stamatoullas, A; Thomas, X; Travade, P | 1 |
Amenomori, T; Atogami, S; Fukushima, T; Hayashibara, T; Honda, M; Ikeda, S; Jinnai, I; Kuriyama, K; Kusano, M; Matsuo, T; Miyazaki, Y; Momita, S; Nagai, K; Nonaka, H; Soda, H; Taguchi, J; Tomonaga, M; Toriya, K; Yoshida, S; Yoshida, Y | 1 |
Powell, BL | 1 |
Consoli, U; Giustolisi, GM; Giustolisi, R; Guglielmo, P; Inghilterra, G; Palumbo, GA; Stagno, F | 1 |
Honma, Y; Ishii, Y; Matsuda, A; Niitsu, N | 1 |
Asahara, S; Chinzei, T; Hasuike, N; Maeda, N; Maeda, Y; Okada, Y; Okutani, T; Saigo, K; Satake, S; Takata, M; Tamura, M; Tasaka, K; Tomofuji, Y | 1 |
Cuneo, A; Liso, V; Mestice, A; Pannunzio, A; Rocchi, M; Specchia, G; Storlazzi, CT; Surace, C | 1 |
Ahmed, T; Feldman, EJ; Kancherla, R; Liu, D; Papageorgio, C; Pozzuoli, M; Seiter, K; Sreekantaiah, C; Weisberger, J; Weiss, M | 1 |
Basu, S; Chachlani, N; Kalk, E; Rose, P | 1 |
Andreeff, M; Chang, S; Estrov, Z; Gribble, G; Harris, D; Honda, T; Jackson, CE; Konopleva, M; Leysath, CE; May, WS; Munsell, M; Ruvolo, P; Sporn, MB; Stiouf, I; Suh, N; Tsao, T; Zhao, S | 1 |
Alimena, G; Breccia, M; Cimino, G; De Carolis, S; Lo Coco, F; Mandelli, F | 1 |
Kakishita, E; Mori, A; Okada, M; Okamoto, T; Takatsuka, H; Wakae, T | 1 |
Dabadghao, S; Melinkeri, SR; Mishra, SK | 1 |
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Burnett, AK; Goldstone, AH; Hills, RK; McMullin, MF; Milligan, D; Prentice, AG; Wheatley, K | 1 |
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Burnett, AK; Duncombe, A; Gibson, B; Goldstone, AH; Hills, RK; McMullin, MF; Milligan, DW; Prentice, AG; Wheatley, K | 1 |
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DiNardo, CD; Kadia, TM; Kantarjian, HM; Ravandi, F; Welch, MA | 1 |
Ahn, MJ; Bae, SH; Bang, SM; Cho, EK; Choi, JH; Chong, SY; Hyun, MS; Jo, DY; Kim, B; Kim, BS; Kim, CS; Kim, DY; Kim, H; Kim, HJ; Kim, HS; Kim, I; Kim, SH; Kwon, H; Lee, JH; Lee, KH; Lee, MH; Lee, WS; Min, YJ; Moon, HN; Mun, YC; Nam, SH; Oh, D; Park, JH; Park, KT; Park, SY; Park, YH; Ryoo, HM; Seo, JJ; Seong, CM; Yoon, HJ; Yoon, SS; Zang, DY | 1 |
Basara, N; Benner, A; Bullinger, L; Cocciardi, S; Döhner, H; Döhner, K; Fiedler, W; Fransecky, L; Gaidzik, VI; Ganser, A; Götze, K; Greil, R; Hertenstein, B; Heuser, M; Kapp-Schwoerer, S; Koller, E; Krauter, J; Krzykalla, J; Kühn, MWM; Leis, C; Lübbert, M; Machherndl-Spandl, S; Martens, UM; Mayer, K; Nachbaur, D; Paschka, P; Ringhoffer, M; Saadati, M; Samra, MA; Schleicher, J; Schlenk, RF; Schrade, A; Schroeder, T; Thol, F; Wattad, M; Weber, D; Wulf, G | 1 |
Cao, H; Chen, S; Chen, Y; Dai, Y; Fan, J; Fang, Y; Gao, C; Gao, J; Han, Y; Hu, Q; Huang, P; Jin, J; Ju, X; Li, J; Liang, C; Liang, H; Lin, L; Lin, W; Liu, A; Liu, W; Peng, X; Peng, Y; Qi, P; Shao, J; Shi, X; Tian, X; Wang, J; Wang, L; Wang, T; Wang, X; Wang, Y; Wu, Y; Xiong, H; Xu, L; Yan, M; Yang, L; Yu, H; Yu, J; Zhai, X; Zhang, J; Zhang, L; Zhang, R; Zhang, Y; Zhao, W; Zheng, H; Zhou, M | 1 |
47 review(s) available for cytarabine and tretinoin
Article | Year |
---|---|
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk | 2016 |
New drugs in acute myelogenous leukemia: a review.
Topics: Amsacrine; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Clinical Trials as Topic; Cytarabine; Daunorubicin; Drug Evaluation; Humans; Idarubicin; Isomerism; Leukemia, Myeloid, Acute; Mitoxantrone; Remission Induction; Survival Rate; Tretinoin | 1992 |
New agents in the treatment of acute myeloid leukemia.
Topics: Acute Disease; Antineoplastic Combined Chemotherapy Protocols; Carboplatin; Cytarabine; Daunorubicin; Drug Evaluation; Etoposide; Humans; Idarubicin; Leukemia, Myeloid; Middle Aged; Mitoxantrone; Remission Induction; Tretinoin | 1991 |
Differentiating agents in the treatment of leukemia.
Topics: Cell Differentiation; Cytarabine; Humans; Interferon Type I; Leukemia; Leukemia, Hairy Cell; Leukemia, Myeloid, Acute; Leukemia, Promyelocytic, Acute; Myelodysplastic Syndromes; Tretinoin | 1990 |
Differentiating agents in the treatment of leukemia and myelodysplastic syndromes.
Topics: Cell Differentiation; Cell Division; Cytarabine; Humans; Interferon Type I; Leukemia; Leukemia, Hairy Cell; Leukemia, Myeloid, Acute; Leukemia, Promyelocytic, Acute; Myelodysplastic Syndromes; Tretinoin | 1990 |
Management of the myelodysplastic syndromes.
Topics: Bone Marrow Transplantation; Cholecalciferol; Combined Modality Therapy; Cytarabine; Hormones; Humans; Myelodysplastic Syndromes; Tretinoin | 1987 |
Differentiation in acute myeloid leukemia and myelodysplastic disorders. Is differentiation-induction therapy possible?
Topics: Cell Differentiation; Cytarabine; Humans; Leukemia, Myeloid, Acute; Myelodysplastic Syndromes; Tretinoin | 1988 |
Treatment of patients with myelodysplastic syndromes: a review.
Topics: Adolescent; Adult; Age Factors; Bone Marrow Transplantation; Cell Differentiation; Child, Preschool; Cytarabine; Drug Therapy, Combination; Female; Hematopoiesis; Humans; Leukemia, Myeloid, Acute; Male; Middle Aged; Myelodysplastic Syndromes; Tretinoin; Vitamin D | 1986 |
[Cell differentiation induction therapy in leukemia].
Topics: Animals; Antineoplastic Combined Chemotherapy Protocols; Cell Cycle; Cell Differentiation; Cell Division; Cell Line; Cytarabine; Humans; Leukemia; Leukemia, Experimental; Tretinoin | 1986 |
Management of myelodysplastic syndromes.
Topics: Androgens; Antineoplastic Combined Chemotherapy Protocols; Bone Marrow Transplantation; Cytarabine; Danazol; Glucocorticoids; Humans; Isotretinoin; Myelodysplastic Syndromes; Pyridoxal Phosphate; Pyridoxine; Tretinoin | 1986 |
Adult leukaemia in 1995: new directions.
Topics: Adult; Aged; Bone Marrow Transplantation; Child; Chromosomes, Human, Pair 22; Chromosomes, Human, Pair 9; Cytarabine; Humans; Leukemia; Leukemia, Myelogenous, Chronic, BCR-ABL Positive; Leukemia, Promyelocytic, Acute; Middle Aged; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Translocation, Genetic; Tretinoin | 1995 |
Treatment of newly diagnosed acute promyelocytic leukemia (APL) by all transretinoic acid (ATRA) combined with chemotherapy: The European experience. European APL Group.
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Bone Marrow Transplantation; Cell Differentiation; China; Combined Modality Therapy; Cytarabine; Daunorubicin; Disease-Free Survival; Etoposide; Europe; Humans; Immunologic Factors; Leukemia, Promyelocytic, Acute; Leukocytosis; Life Tables; Middle Aged; Mitoxantrone; New York; Pilot Projects; Remission Induction; Survival Rate; Treatment Outcome; Tretinoin | 1995 |
Differentiation therapy of myelodysplastic syndromes with retinoic acid.
Topics: Clinical Trials as Topic; Cytarabine; Humans; Myelodysplastic Syndromes; Tretinoin | 1994 |
[Recent development of new anticancer drugs in Japan].
Topics: Aminopterin; Antineoplastic Agents; Camptothecin; Cisplatin; Cytarabine; Irinotecan; Methotrexate; Paclitaxel; Tretinoin; Tubulin Modulators; Vinblastine; Vinorelbine | 1993 |
Acute promyelocytic leukemia and pregnancy. A case report.
Topics: Adult; Antibiotics, Antineoplastic; Antimetabolites, Antineoplastic; Antineoplastic Combined Chemotherapy Protocols; Cytarabine; Daunorubicin; Disseminated Intravascular Coagulation; Female; Fetal Death; Humans; Leukemia, Promyelocytic, Acute; Pregnancy; Pregnancy Complications, Neoplastic; Pregnancy Outcome; Pregnancy Trimester, Second; Prenatal Care; Remission Induction; Tretinoin | 1995 |
Acute promyelocytic leukemia: biology and treatment.
Topics: Antineoplastic Combined Chemotherapy Protocols; Cell Differentiation; Chromosomes, Human, Pair 15; Chromosomes, Human, Pair 17; Cytarabine; Daunorubicin; Humans; Leukemia, Promyelocytic, Acute; Neoplasm, Residual; Recurrence; Translocation, Genetic; Tretinoin | 1997 |
[Progress in the treatment of adult acute myeloid leukemia].
Topics: Adolescent; Adult; Aged; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Clinical Trials as Topic; Cytarabine; Daunorubicin; Drug Resistance, Neoplasm; Humans; Infusions, Intravenous; Leukemia, Myeloid, Acute; Mercaptopurine; Middle Aged; Prednisolone; Tretinoin | 1997 |
New strategies for the treatment of acute promyelocytic leukaemia.
Topics: Antibiotics, Antineoplastic; Antimetabolites, Antineoplastic; Antineoplastic Combined Chemotherapy Protocols; Cytarabine; Disease-Free Survival; Humans; Idarubicin; Leukemia, Promyelocytic, Acute; Remission Induction; Treatment Outcome; Tretinoin | 1997 |
Relapsed acute promyelocytic leukemia previously treated with all-trans retinoic acid: clinical experience with a new synthetic retinoid, Am-80.
Topics: Adult; Aged; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Arsenicals; Benzoates; Biomarkers, Tumor; Cheilitis; Cytarabine; Daunorubicin; Disease-Free Survival; Drug Resistance, Neoplasm; Female; Humans; Hypercholesterolemia; Hypertriglyceridemia; Leukemia, Promyelocytic, Acute; Leukocytosis; Male; Middle Aged; Neoplasm Proteins; Oncogene Proteins, Fusion; Pilot Projects; Recurrence; Remission Induction; Salvage Therapy; Tetrahydronaphthalenes; Treatment Outcome; Tretinoin; Tumor Cells, Cultured | 1998 |
[Oral antitumor drugs for hematological malignancies].
Topics: Administration, Oral; Antineoplastic Agents; Cytarabine; Etoposide; Hematologic Neoplasms; Humans; Hydroxyurea; Leukemia-Lymphoma, Adult T-Cell; Piperazines; Prodrugs; Tretinoin | 1999 |
Acute promyelocytic leukemia. New methods in diagnosis and treatment.
Topics: Aged; Antibiotics, Antineoplastic; Antimetabolites, Antineoplastic; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Chromosomes, Human, Pair 15; Chromosomes, Human, Pair 17; Cytarabine; Daunorubicin; Humans; Leukemia, Promyelocytic, Acute; Male; Translocation, Genetic; Tretinoin | 1999 |
[New combination therapies in hematological malignancies].
Topics: Antibodies, Monoclonal; Antibodies, Monoclonal, Murine-Derived; Antineoplastic Combined Chemotherapy Protocols; Cyclophosphamide; Cyclosporins; Cytarabine; Doxorubicin; Drug Administration Schedule; Granulocyte Colony-Stimulating Factor; Humans; Lymphoma, B-Cell; Myelodysplastic Syndromes; Prednisone; Quinolines; Rituximab; Tretinoin; Vidarabine; Vincristine | 2000 |
[Prognostic factors in chemotherapies for acute myeloid leukemia].
Topics: Antineoplastic Agents; Clinical Trials as Topic; Cytarabine; Humans; Karyotyping; Leukemia, Myeloid, Acute; Multicenter Studies as Topic; Prognosis; Risk Factors; Survival Analysis; Tretinoin | 2000 |
Diagnosis, front line treatment and molecular monitoring of acute promyelocytic leukaemia.
Topics: Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Biomarkers, Tumor; Chromosomes, Human, Pair 15; Chromosomes, Human, Pair 17; Clinical Trials as Topic; Combined Modality Therapy; Cytarabine; Forecasting; Humans; Leukemia, Promyelocytic, Acute; Multicenter Studies as Topic; Neoplasm Proteins; Oncogene Proteins, Fusion; Randomized Controlled Trials as Topic; Remission Induction; Salvage Therapy; Translocation, Genetic; Treatment Outcome; Tretinoin | 1999 |
Acute progranulocytic leukemia.
Topics: Antineoplastic Combined Chemotherapy Protocols; Arsenic Trioxide; Arsenicals; Biomarkers, Tumor; Clinical Trials as Topic; Cytarabine; Humans; Leukemia, Promyelocytic, Acute; Neoplasm, Residual; Oxides; Prognosis; Salvage Therapy; Survival Analysis; Tretinoin | 2001 |
Secondary acute myelogenous leukemia and myelodysplasia without abnormalities of chromosome 11q23 following treatment of acute leukemia with topoisomerase II-based chemotherapy.
Topics: Acute Disease; Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Chromosome Aberrations; Chromosomes, Human, Pair 11; Clinical Trials, Phase II as Topic; Clinical Trials, Phase III as Topic; Cytarabine; Disease Progression; Disease-Free Survival; Enzyme Inhibitors; Etoposide; Female; Humans; Idarubicin; Incidence; Karyotyping; Leukemia, Myeloid; Life Tables; Male; Middle Aged; Mitoxantrone; Myelodysplastic Syndromes; Neoplasm Proteins; Neoplasms, Second Primary; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Randomized Controlled Trials as Topic; Remission Induction; Retrospective Studies; Topoisomerase II Inhibitors; Treatment Outcome; Tretinoin | 2001 |
AIDA treatment for high-risk acute promyelocytic leukemia in a pregnant woman at 21 weeks of gestation.
Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; Cesarean Section; Cytarabine; Disseminated Intravascular Coagulation; Female; Gestational Age; Humans; Idarubicin; Infant, Newborn; Leukemia, Promyelocytic, Acute; Pregnancy; Pregnancy Complications, Hematologic; Pregnancy Complications, Neoplastic; Remission Induction; Risk; Tretinoin | 2002 |
Central nervous system relapse in acute promyelocytic leukemia.
Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; Central Nervous System; Combined Modality Therapy; Cranial Irradiation; Cytarabine; Daunorubicin; Humans; Idarubicin; Leukemia, Promyelocytic, Acute; Leukemic Infiltration; Male; Methotrexate; Tretinoin | 2002 |
[Expanding possibilities, strategic considerations, and novel methods in the diagnosis and chemotherapy of adult acute myeloid leukemia].
Topics: Adult; Anthracyclines; Antibodies, Monoclonal; Antineoplastic Combined Chemotherapy Protocols; Arsenic Trioxide; Arsenicals; Cytarabine; Drug Resistance, Neoplasm; Gene Expression Profiling; Humans; Leukemia, Myeloid, Acute; Leukemia, Promyelocytic, Acute; Oligonucleotide Array Sequence Analysis; Oxides; Palliative Care; Prognosis; Remission Induction; Tretinoin | 2003 |
[Recent advances in the treatment of acute myelogenous leukemia: a view of the new agents].
Topics: Alkyl and Aryl Transferases; Aminoglycosides; Antibodies, Monoclonal; Antibodies, Monoclonal, Humanized; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Arsenic Trioxide; Arsenicals; Benzoates; Cyclosporine; Cytarabine; Daunorubicin; Drug Design; Farnesyltranstransferase; Gemtuzumab; Humans; Leukemia, Myeloid, Acute; Neoplasm Recurrence, Local; Nucleosides; Oxides; Prognosis; Radioisotopes; Remission Induction; Tetrahydronaphthalenes; Topoisomerase Inhibitors; Tretinoin; Verapamil | 2003 |
[Recent progress in diagnosis of and therapy for patients with leukemia].
Topics: Antineoplastic Agents; Benzamides; Clinical Trials as Topic; Cytarabine; Drug Monitoring; Fusion Proteins, bcr-abl; Gene Targeting; Genes, Wilms Tumor; Genetic Therapy; Hematopoietic Stem Cell Transplantation; Humans; Imatinib Mesylate; Leukemia, Myelogenous, Chronic, BCR-ABL Positive; Leukemia, Promyelocytic, Acute; Neoplasm Proteins; Neoplasm, Residual; Oncogene Proteins, Fusion; Pharmacogenetics; Piperazines; Pyrimidines; Recombinant Fusion Proteins; Therapeutic Equivalency; Tretinoin | 2004 |
[Acute promyelocytic leukemia after living donor partial orthotopic liver transplantation].
Topics: Antineoplastic Combined Chemotherapy Protocols; Child; Cytarabine; Daunorubicin; Female; Graft vs Host Disease; Humans; Immunosuppressive Agents; Leukemia, Promyelocytic, Acute; Liver Transplantation; Living Donors; Ornithine Carbamoyltransferase Deficiency Disease; Remission Induction; Tacrolimus; Tretinoin | 2004 |
The expanding role of arsenic in acute promyelocytic leukemia.
Topics: Antineoplastic Combined Chemotherapy Protocols; Arsenic Trioxide; Arsenicals; Clinical Trials as Topic; Cytarabine; Humans; Leukemia, Promyelocytic, Acute; Oxides; Treatment Outcome; Tretinoin | 2008 |
Acquired acute myelogenous leukemia after therapy for acute promyelocytic leukemia with t(15;17): a case report and review of the literature.
Topics: Adult; Antineoplastic Agents, Alkylating; Antineoplastic Combined Chemotherapy Protocols; Chromosomes, Human, Pair 15; Chromosomes, Human, Pair 17; Chromosomes, Human, Pair 21; Chromosomes, Human, Pair 3; Chromosomes, Human, Pair 7; Cytarabine; Daunorubicin; Drug Synergism; Fatal Outcome; Humans; Leukemia, Myeloid, Acute; Leukemia, Promyelocytic, Acute; Male; Mercaptopurine; Methotrexate; Mitoxantrone; Monosomy; Neoplasms, Second Primary; Translocation, Genetic; Tretinoin | 2009 |
[History, current status, and future prospects in clinical study of myeloid leukemia].
Topics: Antineoplastic Agents; Benzamides; Cytarabine; Drug Design; Drug Therapy, Combination; Gene Targeting; Granulocyte Colony-Stimulating Factor; Hematopoietic Stem Cell Transplantation; Humans; Imatinib Mesylate; Leukemia, Myelogenous, Chronic, BCR-ABL Positive; Leukemia, Myeloid, Acute; Piperazines; Precision Medicine; Pyrimidines; Remission Induction; Risk; Tretinoin | 2009 |
[Acute lower limb ischemia revealing acute leukemia. Case report and review of the literature].
Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; Arterial Occlusive Diseases; Cytarabine; Daunorubicin; Emergencies; Femoral Artery; Humans; Ischemia; Leg; Leukemia, Promyelocytic, Acute; Leukostasis; Male; Popliteal Artery; Remission Induction; Thrombectomy; Tretinoin | 2010 |
Is cytarabine required in the treatment of acute promyelocytic leukemia?
Topics: Adult; Anthracyclines; Antimetabolites, Antineoplastic; Antineoplastic Combined Chemotherapy Protocols; Clinical Trials as Topic; Combined Modality Therapy; Cytarabine; Humans; Leukemia, Promyelocytic, Acute; Middle Aged; Multicenter Studies as Topic; Randomized Controlled Trials as Topic; Remission Induction; Treatment Outcome; Tretinoin | 2006 |
Modern approaches to treating acute promyelocytic leukemia.
Topics: Antineoplastic Combined Chemotherapy Protocols; Arsenic Trioxide; Arsenicals; Brain Neoplasms; Cytarabine; Hematopoietic Stem Cell Transplantation; Humans; Leukemia, Promyelocytic, Acute; Oxides; Recurrence; Reverse Transcriptase Polymerase Chain Reaction; Tretinoin | 2011 |
Advances in therapies for acute promyelocytic leukemia.
Topics: Anthracyclines; Antineoplastic Combined Chemotherapy Protocols; Arsenic Trioxide; Arsenicals; Cell Differentiation; Clinical Trials as Topic; Consolidation Chemotherapy; Cytarabine; Disease-Free Survival; Drug Resistance, Neoplasm; Gene Expression Regulation, Leukemic; Hematopoietic Stem Cell Transplantation; Humans; Induction Chemotherapy; Leukemia, Promyelocytic, Acute; Maintenance Chemotherapy; Multicenter Studies as Topic; Oncogene Proteins, Fusion; Oxides; Risk; Salvage Therapy; Tretinoin | 2011 |
Current treatment strategy of acute promyelocytic leukemia.
Topics: Anthracyclines; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Arsenic Trioxide; Arsenicals; Cytarabine; Humans; Leukemia, Promyelocytic, Acute; Oxides; Prognosis; Secondary Prevention; Survival Rate; Tretinoin | 2011 |
[Current treatment of acute myeloid leukaemia in adults].
Topics: Age Factors; Aminoglycosides; Antibodies, Monoclonal, Humanized; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Arsenic Trioxide; Arsenicals; Boronic Acids; Bortezomib; Cytarabine; Disease-Free Survival; Drug Resistance, Neoplasm; fms-Like Tyrosine Kinase 3; Gemtuzumab; Hematopoietic Stem Cell Transplantation; Humans; Idarubicin; Leukemia, Myeloid, Acute; Mitoxantrone; Molecular Targeted Therapy; Oxides; Prognosis; Pyrazines; Recurrence; Transplantation, Homologous; Treatment Outcome; Tretinoin | 2012 |
[Acute promyelocytic leukemia presenting with central nervous system involvement at initial diagnosis].
Topics: Antineoplastic Combined Chemotherapy Protocols; Bone Marrow Cells; Central Nervous System Neoplasms; Cytarabine; Humans; Idarubicin; Leukemia, Promyelocytic, Acute; Male; Middle Aged; Neoplasm Invasiveness; Treatment Outcome; Tretinoin | 2013 |
[Current therapy for acute myeloid leukemia and acute promyelocytic leukemia].
Topics: Antineoplastic Combined Chemotherapy Protocols; Clinical Trials as Topic; Consolidation Chemotherapy; Cytarabine; Daunorubicin; Drug Discovery; Etoposide; Hematopoietic Stem Cell Transplantation; Humans; Idarubicin; Induction Chemotherapy; Leukemia, Myeloid, Acute; Leukemia, Promyelocytic, Acute; Maintenance Chemotherapy; Mercaptopurine; Methotrexate; Molecular Targeted Therapy; Mutation; Recurrence; Tretinoin; Vincristine | 2014 |
Have all-trans retinoic acid and arsenic trioxide replaced all-trans retinoic acid and anthracyclines in APL as standard of care.
Topics: Adult; Age Factors; Aged; Anthracyclines; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Arsenic Trioxide; Arsenicals; Blood Coagulation Factors; Clinical Trials as Topic; Combined Modality Therapy; Cytarabine; Etoposide; Humans; Hydroxyurea; Idarubicin; Leukemia, Promyelocytic, Acute; Maintenance Chemotherapy; Middle Aged; Mitoxantrone; Multicenter Studies as Topic; Oxides; Platelet Transfusion; Practice Guidelines as Topic; Remission Induction; Risk Assessment; Thioguanine; Treatment Outcome; Tretinoin | 2014 |
Gemtuzumab ozogamicin in acute myeloid leukemia: past, present and future.
Topics: Aged; Animals; Antineoplastic Agents; Antineoplastic Agents, Immunological; Antineoplastic Combined Chemotherapy Protocols; Arsenicals; Calicheamicins; Chlorides; Clinical Trials as Topic; Cytarabine; Daunorubicin; Drug Approval; Drug Evaluation, Preclinical; Drug Resistance, Neoplasm; Gemtuzumab; Hematopoietic Stem Cell Transplantation; Humans; Leukemia, Myeloid, Acute; Leukemia, Promyelocytic, Acute; Mice; Middle Aged; Multicenter Studies as Topic; Recurrence; Sialic Acid Binding Ig-like Lectin 3; Tretinoin | 2020 |
Does acute promyelocytic leukemia patient with the STAT5B/RARa fusion gene respond well to decitabine?: A case report and literature review.
Topics: Adolescent; Adult; Aged; Antimetabolites, Antineoplastic; Antineoplastic Agents; Arsenic Trioxide; Asian People; Consolidation Chemotherapy; Cytarabine; Decitabine; Drug Therapy, Combination; Female; Hospitalization; Humans; Idarubicin; Leukemia, Promyelocytic, Acute; Male; Middle Aged; Recurrence; Retinoic Acid Receptor alpha; STAT5 Transcription Factor; Treatment Outcome; Tretinoin | 2020 |
Acute myeloid leukemia: Treatment and research outlook for 2021 and the MD Anderson approach.
Topics: Age Factors; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Arsenic Trioxide; Bridged Bicyclo Compounds, Heterocyclic; Cladribine; Core Binding Factors; Cytarabine; Daunorubicin; Gemtuzumab; Humans; Leukemia, Myeloid, Acute; Leukemia, Promyelocytic, Acute; Maintenance Chemotherapy; Mutation; Myelodysplastic Syndromes; Myeloproliferative Disorders; Neoplasm, Residual; Sulfonamides; Survival Rate; Translational Research, Biomedical; Tretinoin; Vidarabine | 2021 |
88 trial(s) available for cytarabine and tretinoin
Article | Year |
---|---|
All-transretinoic acid followed by intensive chemotherapy gives a high complete remission rate and may prolong remissions in newly diagnosed acute promyelocytic leukemia: a pilot study on 26 cases.
Topics: Actuarial Analysis; Antineoplastic Combined Chemotherapy Protocols; Cyclophosphamide; Cytarabine; Daunorubicin; Female; Follow-Up Studies; Humans; Leukemia, Promyelocytic, Acute; Male; Mercaptopurine; Methotrexate; Middle Aged; Mitoguazone; Pilot Projects; Time Factors; Treatment Outcome; Tretinoin | 1992 |
High-dose cytosine arabinoside remission induction for acute myelogenous leukemia: comparison of two regimens of remission maintenance.
Topics: Acute Disease; Adult; Age Factors; Antineoplastic Combined Chemotherapy Protocols; Bone Marrow Transplantation; Combined Modality Therapy; Cytarabine; Daunorubicin; Humans; Leukemia, Myeloid; Middle Aged; Prednisone; Survival Analysis; Tretinoin | 1992 |
New agents in the treatment of acute myeloid leukemia.
Topics: Acute Disease; Antineoplastic Combined Chemotherapy Protocols; Carboplatin; Cytarabine; Daunorubicin; Drug Evaluation; Etoposide; Humans; Idarubicin; Leukemia, Myeloid; Middle Aged; Mitoxantrone; Remission Induction; Tretinoin | 1991 |
Treatment of myelodysplastic syndromes with retinoic acid and 1 alpha-hydroxy-vitamin D3 in combination with low-dose ara-C is not superior to ara-C alone. Results from a randomized study. The Scandinavian Myelodysplasia Group (SMG).
Topics: Aged; Aged, 80 and over; Cytarabine; Drug Therapy, Combination; Female; Humans; Hydroxycholecalciferols; Leukemia, Myeloid, Acute; Male; Middle Aged; Myelodysplastic Syndromes; Tretinoin | 1990 |
A randomized trial of 13-cis retinoic acid with or without cytosine arabinoside in patients with the myelodysplastic syndrome.
Topics: Adult; Aged; Aged, 80 and over; Clinical Trials as Topic; Cytarabine; Drug Therapy, Combination; Female; Humans; Isomerism; Male; Middle Aged; Myelodysplastic Syndromes; Random Allocation; Tretinoin | 1987 |
Combination of low-dose cytarabine and 13-cis retinoic acid in the treatment of myelodysplastic syndromes.
Topics: Adult; Aged; Cell Differentiation; Clinical Trials as Topic; Cytarabine; Drug Synergism; Drug Therapy, Combination; Female; Humans; Male; Middle Aged; Myelodysplastic Syndromes; Skin Diseases; Tretinoin | 1987 |
All-trans retinoic acid and low-dose cytosine arabinoside for the treatment of 'poor prognosis' acute myeloid leukemia.
Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Bone Marrow; Cytarabine; Drug Administration Schedule; Female; Humans; Leukemia, Myeloid, Acute; Male; Middle Aged; Prognosis; Remission Induction; Tretinoin | 1995 |
Treatment of newly diagnosed acute promyelocytic leukemia (APL) by all transretinoic acid (ATRA) combined with chemotherapy: The European experience. European APL Group.
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Bone Marrow Transplantation; Cell Differentiation; China; Combined Modality Therapy; Cytarabine; Daunorubicin; Disease-Free Survival; Etoposide; Europe; Humans; Immunologic Factors; Leukemia, Promyelocytic, Acute; Leukocytosis; Life Tables; Middle Aged; Mitoxantrone; New York; Pilot Projects; Remission Induction; Survival Rate; Treatment Outcome; Tretinoin | 1995 |
Results of APL 91 European trial combining ATRA and chemotherapy: presentation of APL 1993 trial.
Topics: Antineoplastic Combined Chemotherapy Protocols; Cytarabine; Daunorubicin; Disease-Free Survival; Drug Administration Schedule; Europe; Humans; Leukemia, Promyelocytic, Acute; Leukocyte Count; Mercaptopurine; Methotrexate; Recurrence; Remission Induction; Treatment Outcome; Tretinoin | 1994 |
All-trans retinoic acid for the treatment of newly diagnosed acute promyelocytic leukemia. Japan Adult Leukemia Study Group.
Topics: Adolescent; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Combined Modality Therapy; Cytarabine; Daunorubicin; Female; Humans; Immunologic Factors; Japan; Leukemia, Promyelocytic, Acute; Leukocytosis; Life Tables; Male; Mercaptopurine; Middle Aged; Prednisolone; Prospective Studies; Remission Induction; Syndrome; Treatment Outcome; Tretinoin | 1995 |
Pre-treatment with all-trans retinoic acid accelerates polymorphonuclear recovery after chemotherapy in patients with acute promyelocytic leukemia.
Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; Cytarabine; Daunorubicin; Female; Hematopoiesis; Humans; Idarubicin; Immunologic Factors; Leukemia, Promyelocytic, Acute; Leukocyte Count; Leukocytosis; Male; Middle Aged; Neutrophils; Platelet Count; Premedication; Remission Induction; Salvage Therapy; Treatment Outcome; Tretinoin | 1994 |
Tretinoin with chemotherapy in newly diagnosed acute promyelocytic leukaemia. European APL Group.
Topics: Antineoplastic Combined Chemotherapy Protocols; Cytarabine; Daunorubicin; Humans; Leukemia, Promyelocytic, Acute; Tretinoin | 1994 |
[Effect of treatment with 13-cis-retinoic acid and ara-C on the hematopoietic stem cells of patients with myelodysplastic syndromes].
Topics: Blood Cell Count; Bone Marrow; Cell Differentiation; Cells, Cultured; Colony-Forming Units Assay; Cytarabine; Hematopoiesis; Hematopoietic Stem Cells; Humans; Myelodysplastic Syndromes; Remission Induction; Tretinoin | 1994 |
Treatment of acute promyelocytic leukemia with all-trans retinoic acid. A five-year experience.
Topics: Adolescent; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Child; Child, Preschool; Cytarabine; Female; Harringtonines; Humans; Infant; Leukemia, Promyelocytic, Acute; Male; Middle Aged; Prednisone; Remission Induction; Tretinoin; Vincristine | 1993 |
Morbidity and costs of remission induction therapy with all-trans retinoic acid compared with standard chemotherapy in acute promyelocytic leukemia.
Topics: Adolescent; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Cohort Studies; Cytarabine; Daunorubicin; Drug Therapy; Female; Humans; Idarubicin; Leukemia, Promyelocytic, Acute; Male; Middle Aged; Remission Induction; Time Factors; Tretinoin | 1994 |
Rapid achievement of PML-RAR alpha polymerase chain reaction (PCR)-negativity by combined treatment with all-trans-retinoic acid and chemotherapy in acute promyelocytic leukemia: a pilot study.
Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Base Sequence; Chromosomes, Human, Pair 15; Cytarabine; Daunorubicin; Humans; Leukemia, Promyelocytic, Acute; Molecular Sequence Data; Pilot Projects; Polymerase Chain Reaction; Receptors, Retinoic Acid; Retinoic Acid Receptor alpha; Sensitivity and Specificity; Tretinoin | 1994 |
Thrombosis in patients with acute promyelocytic leukemia treated with and without all-trans retinoic acid.
Topics: Adult; Amsacrine; Antibiotics, Antineoplastic; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Cerebral Hemorrhage; Cohort Studies; Cytarabine; Disseminated Intravascular Coagulation; Fatal Outcome; Female; Germinoma; Hemorrhage; Humans; Idarubicin; Incidence; Infarction; Leukemia, Promyelocytic, Acute; Leukocytosis; Male; Melanoma; Middle Aged; Myocardial Infarction; Neoplasms, Multiple Primary; Remission Induction; Retrospective Studies; Spleen; Thrombosis; Treatment Outcome; Tretinoin | 1996 |
All-trans retinoic acid (ATRA) in the treatment of acute promyelocytic leukemia (APL).
Topics: Adolescent; Adult; Aged; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Cohort Studies; Cytarabine; Daunorubicin; Disease-Free Survival; Female; Humans; Leukemia, Promyelocytic, Acute; Life Tables; Male; Middle Aged; Neoplasm Proteins; Oncogene Proteins, Fusion; Prospective Studies; Remission Induction; Salvage Therapy; Survival Analysis; Treatment Outcome; Tretinoin | 1996 |
All-trans retinoic acid in relapsing malignant gliomas: clinical and radiological stabilization associated with the appearance of intratumoral calcifications.
Topics: Adult; Aged; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Astrocytoma; Brain Neoplasms; Calcinosis; Cytarabine; Disease Progression; Female; Glioblastoma; Glioma; Humans; Magnetic Resonance Imaging; Male; Middle Aged; Neoplasm Recurrence, Local; Radiography; Time Factors; Tretinoin | 1997 |
Treatment with a new synthetic retinoid, Am80, of acute promyelocytic leukemia relapsed from complete remission induced by all-trans retinoic acid.
Topics: Adult; Aged; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Benzoates; Cell Differentiation; Chemical and Drug Induced Liver Injury; Combined Modality Therapy; Cytarabine; Daunorubicin; Drug Resistance, Neoplasm; Female; Gastrointestinal Diseases; Humans; Leukemia, Promyelocytic, Acute; Leukocytosis; Male; Middle Aged; Pain; Prospective Studies; Receptors, Retinoic Acid; Recurrence; Remission Induction; Retinoic Acid Receptor gamma; Retinoids; Salvage Therapy; Tetrahydronaphthalenes; Treatment Outcome; Tretinoin | 1997 |
[Treatment results in childhood acute myeloblastic leukemia--a report of clinical trials of a past decade from the Japanese children's Cancer and Leukemia Study Group (CCLSG)].
Topics: Anthracyclines; Antineoplastic Combined Chemotherapy Protocols; Child; Cytarabine; Humans; Leukemia, Myeloid, Acute; Remission Induction; Tretinoin | 1997 |
All-trans-retinoic acid in acute promyelocytic leukemia.
Topics: Adolescent; Adult; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Child; Child, Preschool; Cytarabine; Daunorubicin; Disease-Free Survival; Female; Humans; Leukemia, Promyelocytic, Acute; Male; Middle Aged; Remission Induction; Survival Rate; Treatment Failure; Tretinoin | 1997 |
Effect of all-trans-retinoic acid alone or in combination with chemotherapy in newly diagnosed acute promyelocytic leukaemia.
Topics: Adolescent; Adult; Aged; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Cytarabine; Daunorubicin; Female; Follow-Up Studies; Humans; Leukemia, Promyelocytic, Acute; Male; Middle Aged; Tretinoin | 1997 |
[Treatment results of intermittent and cyclic regimen with ATRA and chemotherapy in childhood acute promyelocytic leukemia. Children's Cancer and Leukemia Study Group].
Topics: Aclarubicin; Administration, Oral; Adolescent; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Child; Cyclophosphamide; Cytarabine; Daunorubicin; Doxorubicin; Drug Administration Schedule; Female; Humans; Leukemia, Promyelocytic, Acute; Male; Mercaptopurine; Prednisolone; Tretinoin; Vincristine | 1997 |
All trans retinoic acid with low dose cytosine arabinoside in the treatment of myelodysplastic syndrome.
Topics: Aged; Antineoplastic Agents; Cytarabine; Dose-Response Relationship, Drug; Drug Administration Schedule; Female; Humans; Male; Middle Aged; Myelodysplastic Syndromes; Pilot Projects; Prospective Studies; Treatment Outcome; Tretinoin | 1998 |
Leukemic cellular retinoic acid resistance and missense mutations in the PML-RARalpha fusion gene after relapse of acute promyelocytic leukemia from treatment with all-trans retinoic acid and intensive chemotherapy.
Topics: Adolescent; Adult; Aged; Antibiotics, Antineoplastic; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Cell Differentiation; Cytarabine; Daunorubicin; DNA Mutational Analysis; DNA, Neoplasm; Drug Resistance, Neoplasm; Drug Screening Assays, Antitumor; Female; Humans; Leukemia, Promyelocytic, Acute; Male; Middle Aged; Neoplasm Proteins; Neoplasm Recurrence, Local; Neoplastic Stem Cells; Oncogene Proteins, Fusion; Point Mutation; Remission Induction; Tretinoin; Tumor Cells, Cultured | 1998 |
Incidence, clinical features, and outcome of all trans-retinoic acid syndrome in 413 cases of newly diagnosed acute promyelocytic leukemia. The European APL Group.
Topics: Acute Kidney Injury; Adult; Aged; Antibiotics, Antineoplastic; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Cardiovascular Diseases; Cytarabine; Dexamethasone; Disease-Free Survival; Female; Humans; Incidence; Leukemia, Promyelocytic, Acute; Leukocyte Count; Life Tables; Male; Middle Aged; Pericardial Effusion; Pleural Effusion; Proportional Hazards Models; Remission Induction; Respiration Disorders; Survival Rate; Syndrome; Treatment Outcome; Tretinoin | 1998 |
Relapsed acute promyelocytic leukemia previously treated with all-trans retinoic acid: clinical experience with a new synthetic retinoid, Am-80.
Topics: Adult; Aged; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Arsenicals; Benzoates; Biomarkers, Tumor; Cheilitis; Cytarabine; Daunorubicin; Disease-Free Survival; Drug Resistance, Neoplasm; Female; Humans; Hypercholesterolemia; Hypertriglyceridemia; Leukemia, Promyelocytic, Acute; Leukocytosis; Male; Middle Aged; Neoplasm Proteins; Oncogene Proteins, Fusion; Pilot Projects; Recurrence; Remission Induction; Salvage Therapy; Tetrahydronaphthalenes; Treatment Outcome; Tretinoin; Tumor Cells, Cultured | 1998 |
Acute promyelocytic leukemia: all-trans retinoic acid (ATRA) along with chemotherapy is superior to ATRA alone.
Topics: Adolescent; Adult; Antineoplastic Combined Chemotherapy Protocols; Cause of Death; Child; Cytarabine; Daunorubicin; Female; Fever; Humans; Leukemia, Promyelocytic, Acute; Lung; Male; Middle Aged; Prospective Studies; Recurrence; Remission Induction; Survival Rate; Tretinoin; Weight Gain | 1999 |
Randomized phase II study of fludarabine + cytosine arabinoside + idarubicin +/- all-trans retinoic acid +/- granulocyte colony-stimulating factor in poor prognosis newly diagnosed acute myeloid leukemia and myelodysplastic syndrome.
Topics: Acute Disease; Aged; Antineoplastic Combined Chemotherapy Protocols; Combined Modality Therapy; Cytarabine; Granulocyte Colony-Stimulating Factor; Humans; Idarubicin; Leukemia, Myeloid; Middle Aged; Myelodysplastic Syndromes; Probability; Prognosis; Survival Rate; Time Factors; Tretinoin; Vidarabine | 1999 |
Short-term intensive consolidation therapy after all-trans retinoic acid in acute promyelocytic leukemia.
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Cytarabine; Female; Humans; Leukemia, Promyelocytic, Acute; Male; Middle Aged; Mitoxantrone; Prospective Studies; Remission Induction; Survival Analysis; Tretinoin | 1999 |
Treatment of unfavorable myelodysplastic syndrome with all-trans-retinoic acid and subcutaneous Ara C.
Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Cell Differentiation; Cytarabine; Female; Humans; Injections, Subcutaneous; Male; Middle Aged; Myelodysplastic Syndromes; Risk Factors; Tretinoin | 1999 |
[Effectiveness of trans-retinoic acid in the treatment of acute promyelocytic leukemia: initial results of a multicenter study].
Topics: Adolescent; Adult; Antimetabolites, Antineoplastic; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Cytarabine; Daunorubicin; Female; Humans; Leukemia, Promyelocytic, Acute; Male; Middle Aged; Remission Induction; Time Factors; Treatment Outcome; Tretinoin | 1999 |
Therapy of molecular relapse in acute promyelocytic leukemia.
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Cytarabine; Follow-Up Studies; Humans; Idarubicin; Leukemia, Promyelocytic, Acute; Middle Aged; Mitoxantrone; Neoplasm Proteins; Oncogene Proteins, Fusion; Recurrence; Remission Induction; Reverse Transcriptase Polymerase Chain Reaction; Salvage Therapy; Survival Analysis; Time Factors; Tretinoin | 1999 |
Clinical description of 44 patients with acute promyelocytic leukemia who developed the retinoic acid syndrome.
Topics: Adolescent; Adult; Aged; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Child; Child, Preschool; Cytarabine; Daunorubicin; Dexamethasone; Female; Fever; Glucocorticoids; Humans; Incidence; Infant; Leukemia, Promyelocytic, Acute; Lung; Male; Middle Aged; Pericardial Effusion; Pleural Effusion; Remission Induction; Respiratory Distress Syndrome; Syndrome; Tretinoin; Weight Gain | 2000 |
Unexpected high incidence of severe toxicities associated with alpha interferon, low-dose cytosine arabinoside and all-trans retinoic acid in patients with chronic myelogenous leukemia.
Topics: Adult; Aged; Antimetabolites, Antineoplastic; Antineoplastic Combined Chemotherapy Protocols; Ataxia; Combined Modality Therapy; Cytarabine; Drug Administration Schedule; Female; Femur Head Necrosis; Humans; Immunologic Factors; Interferon-alpha; Leukemia, Myelogenous, Chronic, BCR-ABL Positive; Leukocytosis; Life Tables; Male; Middle Aged; Paranoid Disorders; Pilot Projects; Pseudotumor Cerebri; Pulmonary Edema; Red-Cell Aplasia, Pure; Remission Induction; Survival Analysis; Syncope; Treatment Outcome; Tretinoin | 1999 |
Molecular analysis and clinical outcome of adult APL patients with the type V PML-RARalpha isoform: results from intergroup protocol 0129.
Topics: Adult; Amino Acid Sequence; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Base Sequence; Cytarabine; Daunorubicin; Exons; Female; Humans; Karyotyping; Leukemia, Promyelocytic, Acute; Male; Middle Aged; Neoplasm Proteins; Oncogene Proteins, Fusion; Prognosis; Protein Isoforms; Remission Induction; Sequence Deletion; Transcription, Genetic; Tretinoin | 2000 |
Clinical and laboratory evaluation of all-trans retinoic acid modulation of chemotherapy in patients with acute myelogenous leukaemia.
Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Apoptosis; Cytarabine; Female; Genes, bcl-2; Humans; Leukemia, Myeloid, Acute; Male; Middle Aged; Proto-Oncogene Proteins c-bcl-2; Recurrence; Survival Analysis; Treatment Outcome; Tretinoin | 2000 |
A phase-II trial of all trans retinoic acid and low-dose cytosine arabinoside for the treatment of high-risk myelodysplastic syndromes.
Topics: Administration, Oral; Adult; Aged; Aged, 80 and over; Anemia; Cytarabine; Dose-Response Relationship, Drug; Female; Humans; Hypertriglyceridemia; Infections; Male; Middle Aged; Myelodysplastic Syndromes; Neutropenia; Thrombocytopenia; Tretinoin | 2000 |
Phase II evaluation of a high-dose mitoxantrone based induction regimen in untreated adults with acute myeloid leukemia.
Topics: Actuarial Analysis; Acute Disease; Adult; Antineoplastic Combined Chemotherapy Protocols; Bone Marrow Transplantation; Combined Modality Therapy; Conjunctivitis; Cytarabine; Disease-Free Survival; Etoposide; Female; Gastrointestinal Diseases; Humans; Hyperbilirubinemia; Leukemia, Myeloid; Male; Methylprednisolone; Middle Aged; Mitoxantrone; Remission Induction; Risk; Stomatitis; Stroke Volume; Survival Analysis; Survival Rate; Treatment Outcome; Tretinoin; Ventricular Dysfunction, Left | 2000 |
Double induction strategy including high dose cytarabine in combination with all-trans retinoic acid: effects in patients with newly diagnosed acute promyelocytic leukemia. German AML Cooperative Group.
Topics: Adolescent; Adult; Antineoplastic Combined Chemotherapy Protocols; Base Sequence; Cytarabine; DNA Primers; Female; Humans; Leukemia, Promyelocytic, Acute; Male; Middle Aged; Tretinoin | 2000 |
Definition of relapse risk and role of nonanthracycline drugs for consolidation in patients with acute promyelocytic leukemia: a joint study of the PETHEMA and GIMEMA cooperative groups.
Topics: Adolescent; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Cohort Studies; Cytarabine; Etoposide; Female; Humans; Idarubicin; Leukemia, Promyelocytic, Acute; Male; Middle Aged; Mitoxantrone; Multivariate Analysis; Predictive Value of Tests; Recurrence; Risk; Thioguanine; Tretinoin | 2000 |
[Treatment of acute promyelocytic leukemia with all-trans retinoic acid and chemotherapy--multicenter trial of the Japan Adult Leukemia Study Group (JALSG)].
Topics: Aclarubicin; Adolescent; Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Cytarabine; Disease-Free Survival; Drug Administration Schedule; Female; Humans; Leukemia, Promyelocytic, Acute; Male; Mercaptopurine; Middle Aged; Mitoxantrone; Prognosis; Receptors, Retinoic Acid; Remission Induction; Retinoic Acid Receptor alpha; Tretinoin | 2000 |
All-trans retinoic acid significantly reduces the incidence of early hemorrhagic death during induction therapy of acute promyelocytic leukemia.
Topics: Antineoplastic Combined Chemotherapy Protocols; Bone Marrow Transplantation; Cytarabine; Daunorubicin; Hemorrhage; Humans; Leukemia, Promyelocytic, Acute; Mercaptopurine; Methotrexate; Remission Induction; Retrospective Studies; Tretinoin | 2000 |
Additional chromosomal abnormalities in patients with acute promyelocytic leukaemia (APL) do not confer poor prognosis: results of APL 93 trial.
Topics: Adult; Anthracyclines; Antineoplastic Combined Chemotherapy Protocols; Chromosome Aberrations; Chromosomes, Human, Pair 12; Chromosomes, Human, Pair 15; Chromosomes, Human, Pair 16; Chromosomes, Human, Pair 17; Chromosomes, Human, Pair 21; Chromosomes, Human, Pair 6; Chromosomes, Human, Pair 7; Chromosomes, Human, Pair 8; Chromosomes, Human, Pair 9; Cohort Studies; Cytarabine; Daunorubicin; Disease-Free Survival; Female; Humans; Leukemia, Promyelocytic, Acute; Male; Middle Aged; Prognosis; Remission Induction; Survival Rate; Translocation, Genetic; Tretinoin; Trisomy | 2000 |
Cuban experience in the treatment of acute promyelocytic leukemia with ALL transretinoic acid followed by intensive chemotherapy.
Topics: Antineoplastic Combined Chemotherapy Protocols; Cuba; Cytarabine; Daunorubicin; Follow-Up Studies; Humans; Leukemia, Promyelocytic, Acute; Remission Induction; Survival Rate; Treatment Outcome; Tretinoin | 2002 |
All trans retinoic acid in combination with intermediate-dose cytarabine and idarubicin in patients with relapsed or refractory non promyelocytic acute myeloid leukemia: a phase II randomized trial.
Topics: Acute Disease; Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Cytarabine; Female; Humans; Idarubicin; Leukemia, Myeloid; Male; Middle Aged; Remission Induction; Salvage Therapy; Survival Analysis; Therapeutic Equivalency; Treatment Outcome; Tretinoin | 2002 |
All-trans retinoic acid in acute promyelocytic leukemia: long-term outcome and prognostic factor analysis from the North American Intergroup protocol.
Topics: Adolescent; Adult; Aged; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Child; Child, Preschool; Cytarabine; Daunorubicin; Disease-Free Survival; Female; Follow-Up Studies; Humans; Infant; Leukemia, Promyelocytic, Acute; Leukocyte Count; Life Tables; Male; Middle Aged; Prognosis; Remission Induction; Survival Analysis; Treatment Outcome; Tretinoin | 2002 |
Timed sequential therapy of acute myelogenous leukemia in adults: a phase II study of retinoids in combination with the sequential administration of cytosine arabinoside, idarubicin and etoposide.
Topics: Adult; Age Factors; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Cytarabine; Drug Administration Schedule; Etoposide; Female; Humans; Idarubicin; Leukemia, Myeloid, Acute; Male; Middle Aged; Remission Induction; Risk Factors; Survival Analysis; Treatment Outcome; Tretinoin | 2003 |
Outcome of childhood acute promyelocytic leukemia with all-trans-retinoic acid and chemotherapy.
Topics: Adolescent; Adult; Antineoplastic Combined Chemotherapy Protocols; Child; Child, Preschool; Cytarabine; Daunorubicin; Female; Humans; Infant; Leukemia, Promyelocytic, Acute; Male; Middle Aged; Treatment Outcome; Tretinoin | 2004 |
[Preliminary results of a multicenter randomized study on the treatment of acute promyelocytic leukemias].
Topics: Adolescent; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Biomarkers, Tumor; Cytarabine; Daunorubicin; Disease-Free Survival; Drug Administration Schedule; Female; Humans; Leukemia, Promyelocytic, Acute; Male; Middle Aged; Neoplasm Proteins; Oncogene Proteins, Fusion; Protein-Tyrosine Kinases; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-bcr; Remission Induction; Transcription, Genetic; Tretinoin | 2004 |
Phase III study of all-trans retinoic acid in previously untreated patients 61 years or older with acute myeloid leukemia.
Topics: Acute Disease; Aged; Aged, 80 and over; Anemia, Refractory, with Excess of Blasts; Antineoplastic Combined Chemotherapy Protocols; Combined Modality Therapy; Cytarabine; Etoposide; Humans; Idarubicin; Leukemia, Myeloid; Middle Aged; Prognosis; Remission Induction; Survival Rate; Transplantation, Homologous; Tretinoin | 2004 |
High-dose cytarabine and mitoxantrone in consolidation therapy for acute promyelocytic leukemia.
Topics: Adolescent; Adult; Antineoplastic Combined Chemotherapy Protocols; Cytarabine; Female; fms-Like Tyrosine Kinase 3; Humans; Idarubicin; Leukemia, Promyelocytic, Acute; Male; Middle Aged; Mitoxantrone; Prognosis; Proto-Oncogene Proteins; Receptor Protein-Tyrosine Kinases; Remission Induction; Tretinoin | 2005 |
Fludarabine and cytosine are less effective than standard ADE chemotherapy in high-risk acute myeloid leukemia, and addition of G-CSF and ATRA are not beneficial: results of the MRC AML-HR randomized trial.
Topics: Adolescent; Adult; Aged; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Cytarabine; Daunorubicin; Disease-Free Survival; Etoposide; Female; Filgrastim; Granulocyte Colony-Stimulating Factor; Humans; Leukemia, Myeloid, Acute; Male; Middle Aged; Recombinant Proteins; Remission Induction; Retrospective Studies; Risk Factors; Survival Rate; Treatment Outcome; Tretinoin | 2006 |
Repetitive cycles of high-dose cytarabine are effective for childhood acute myeloid leukemia: long-term outcome of the children with AML treated on two consecutive trials of Tokyo Children's Cancer Study Group.
Topics: Acute Disease; Adolescent; Antimetabolites, Antineoplastic; Antineoplastic Combined Chemotherapy Protocols; Child; Child, Preschool; Combined Modality Therapy; Cytarabine; Disease-Free Survival; Down Syndrome; Doxorubicin; Drug Administration Schedule; Etoposide; Female; Hematopoietic Stem Cell Transplantation; Humans; Hydrocortisone; Infant; Infections; Japan; Kaplan-Meier Estimate; Leukemia, Myeloid; Male; Methotrexate; Mitoxantrone; Remission Induction; Survival Analysis; Transplantation, Autologous; Transplantation, Homologous; Treatment Outcome; Tretinoin; Vincristine | 2007 |
Is cytarabine useful in the treatment of acute promyelocytic leukemia? Results of a randomized trial from the European Acute Promyelocytic Leukemia Group.
Topics: Adult; Antimetabolites, Antineoplastic; Antineoplastic Combined Chemotherapy Protocols; Cytarabine; Daunorubicin; Drug Administration Schedule; Female; Humans; Leukemia, Promyelocytic, Acute; Male; Middle Aged; Remission Induction; Survival Analysis; Tretinoin | 2006 |
Outcome of patients with acute promyelocytic leukemia failing to front-line treatment with all-trans retinoic acid and anthracycline-based chemotherapy (PETHEMA protocols LPA96 and LPA99): benefit of an early intervention.
Topics: Adolescent; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Biomarkers, Tumor; Child; Child, Preschool; Combined Modality Therapy; Cytarabine; Etoposide; Female; Hematopoietic Stem Cell Transplantation; Humans; Idarubicin; Kaplan-Meier Estimate; Leukemia, Promyelocytic, Acute; Liposomes; Male; Middle Aged; Mitoxantrone; Neoplasm, Residual; Oncogene Proteins, Fusion; Prognosis; Recurrence; Remission Induction; Salvage Therapy; Survival Analysis; Time Factors; Treatment Outcome; Tretinoin | 2007 |
A comparison of low-dose cytarabine and hydroxyurea with or without all-trans retinoic acid for acute myeloid leukemia and high-risk myelodysplastic syndrome in patients not considered fit for intensive treatment.
Topics: Acute Disease; Aged; Antineoplastic Combined Chemotherapy Protocols; Cytarabine; Female; Humans; Hydroxyurea; Leukemia, Myeloid; Male; Middle Aged; Myelodysplastic Syndromes; Risk; Survival; Treatment Outcome; Tretinoin | 2007 |
Twice daily fludarabine/Ara-C associated to idarubicin, G-CSF and ATRA is an effective salvage regimen in non-promyelocytic acute myeloid leukemia.
Topics: Adolescent; Adult; Antineoplastic Combined Chemotherapy Protocols; Cytarabine; Disease-Free Survival; Female; Granulocyte Colony-Stimulating Factor; Humans; Idarubicin; Leukemia, Myeloid, Acute; Male; Middle Aged; Prospective Studies; Remission Induction; Salvage Therapy; Survival Rate; Tretinoin; Vidarabine | 2009 |
High dose ara-C in the treatment of newly diagnosed acute promyelocytic leukemia: long-term results of the German AMLCG.
Topics: Adolescent; Adult; Antineoplastic Combined Chemotherapy Protocols; Cytarabine; Germany; Humans; Leukemia, Promyelocytic, Acute; Longitudinal Studies; Lymphocyte Count; Middle Aged; Prognosis; Remission Induction; Survival Analysis; Treatment Outcome; Tretinoin; Young Adult | 2009 |
Treatment of children with acute promyelocytic leukemia: results of the first North American Intergroup trial INT0129.
Topics: Adolescent; Child; Child, Preschool; Cytarabine; Daunorubicin; Female; Humans; Infant; Leukemia, Promyelocytic, Acute; Male; Remission Induction; Survival Analysis; Treatment Outcome; Tretinoin | 2009 |
The impact on outcome of the addition of all-trans retinoic acid to intensive chemotherapy in younger patients with nonacute promyelocytic acute myeloid leukemia: overall results and results in genotypic subgroups defined by mutations in NPM1, FLT3, and C
Topics: Adolescent; Adult; Antineoplastic Combined Chemotherapy Protocols; CCAAT-Enhancer-Binding Proteins; Child; Child, Preschool; Cytarabine; Daunorubicin; Female; fms-Like Tyrosine Kinase 3; Gene Expression Regulation, Leukemic; Genotype; Humans; Infant; Infant, Newborn; Leukemia, Promyelocytic, Acute; Male; Middle Aged; Mutation; Nuclear Proteins; Nucleophosmin; Reverse Transcriptase Polymerase Chain Reaction; Thioguanine; Treatment Outcome; Tretinoin; Young Adult | 2010 |
Very long-term outcome of acute promyelocytic leukemia after treatment with all-trans retinoic acid and chemotherapy: the European APL Group experience.
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Cytarabine; Disease-Free Survival; Europe; Female; Follow-Up Studies; Humans; Leukemia, Promyelocytic, Acute; Male; Middle Aged; Time Factors; Treatment Outcome; Tretinoin | 2010 |
Attempts to optimize induction and consolidation treatment in acute myeloid leukemia: results of the MRC AML12 trial.
Topics: Adolescent; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Child; Child, Preschool; Cytarabine; Daunorubicin; Etoposide; Female; Humans; Infant; Infant, Newborn; Leukemia, Myeloid, Acute; Male; Middle Aged; Mitoxantrone; Neoplasm Staging; Prognosis; Remission Induction; Survival Rate; Thioguanine; Treatment Outcome; Tretinoin; Young Adult | 2010 |
Single cycle of arsenic trioxide-based consolidation chemotherapy spares anthracycline exposure in the primary management of acute promyelocytic leukemia.
Topics: Adolescent; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Arsenic Trioxide; Arsenicals; Child; Child, Preschool; Cytarabine; Daunorubicin; Female; Humans; Leukemia, Promyelocytic, Acute; Male; Middle Aged; Neoplasm Recurrence, Local; Neoplasm Staging; Oxides; Prognosis; Remission Induction; Survival Rate; Treatment Outcome; Tretinoin; Young Adult | 2010 |
Favourable outcome of patients with childhood acute promyelocytic leukaemia after treatment with reduced cumulative anthracycline doses.
Topics: Adolescent; Anthracyclines; Antineoplastic Combined Chemotherapy Protocols; Cardiomyopathies; Child; Child, Preschool; Cytarabine; Drug Administration Schedule; Female; Humans; Infant; Infant, Newborn; Leukemia, Promyelocytic, Acute; Male; Neoplasms, Second Primary; Recurrence; Survival Analysis; Treatment Outcome; Tretinoin | 2010 |
Risk-adapted treatment of acute promyelocytic leukemia based on all-trans retinoic acid and anthracycline with addition of cytarabine in consolidation therapy for high-risk patients: further improvements in treatment outcome.
Topics: Adolescent; Adult; Aged; Anthracyclines; Antineoplastic Combined Chemotherapy Protocols; Cytarabine; Disease-Free Survival; Female; Humans; Leukemia, Myeloid, Acute; Male; Middle Aged; Risk Adjustment; Risk Factors; Survival Rate; Tretinoin | 2010 |
Front-line treatment of acute promyelocytic leukemia with AIDA induction followed by risk-adapted consolidation for adults younger than 61 years: results of the AIDA-2000 trial of the GIMEMA Group.
Topics: Adolescent; Adult; Anthracyclines; Antibiotics, Antineoplastic; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Cytarabine; Humans; Idarubicin; Leukemia, Promyelocytic, Acute; Middle Aged; Remission Induction; Tretinoin; Young Adult | 2010 |
Arsenic trioxide improves event-free and overall survival for adults with acute promyelocytic leukemia: North American Leukemia Intergroup Study C9710.
Topics: Adolescent; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Arsenic Trioxide; Arsenicals; Cytarabine; Daunorubicin; Disease-Free Survival; Female; Humans; Leukemia, Promyelocytic, Acute; Male; Mercaptopurine; Methotrexate; Middle Aged; North America; Oxides; Survival Analysis; Treatment Outcome; Tretinoin; Young Adult | 2010 |
Prospective study of a therapeutic regimen with all-trans retinoic acid and anthracyclines in combination of cytarabine in children with acute promyelocytic leukaemia: the Japanese childhood acute myeloid leukaemia cooperative study.
Topics: Adolescent; Anthracyclines; Antineoplastic Combined Chemotherapy Protocols; Child; Child, Preschool; Chromosome Aberrations; Cytarabine; Epidemiologic Methods; Female; Humans; Infant; Leukemia, Promyelocytic, Acute; Leukocyte Count; Male; Neoplasm, Residual; Neutropenia; Prognosis; Recurrence; Treatment Outcome; Tretinoin | 2011 |
Does microgranular variant morphology of acute promyelocytic leukemia independently predict a less favorable outcome compared with classical M3 APL? A joint study of the North American Intergroup and the PETHEMA Group.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Child; Child, Preschool; Cytarabine; Daunorubicin; Female; Follow-Up Studies; Humans; Infant; Leukemia, Promyelocytic, Acute; Male; Middle Aged; Neoplasm Recurrence, Local; Remission Induction; Survival Rate; Treatment Outcome; Tretinoin; Young Adult | 2010 |
GIMEMA AIDA 0493 amended protocol for elderly patients with acute promyelocytic leukaemia. Long-term results and prognostic factors.
Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Cytarabine; Hemorrhage; Humans; Idarubicin; Leukemia, Promyelocytic, Acute; Male; Middle Aged; Opportunistic Infections; Prognosis; Remission Induction; Survival Analysis; Tretinoin | 2011 |
Oral arsenic trioxide-based maintenance regimens for first complete remission of acute promyelocytic leukemia: a 10-year follow-up study.
Topics: Administration, Oral; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Arsenic Trioxide; Arsenicals; Ascorbic Acid; Cytarabine; Daunorubicin; Disease-Free Survival; Dyspepsia; Female; Follow-Up Studies; Headache; Humans; Leukemia, Promyelocytic, Acute; Male; Middle Aged; Oxides; Recurrence; Remission Induction; Time Factors; Treatment Outcome; Tretinoin | 2011 |
The early addition of arsenic trioxide versus high-dose arabinoside is more effective and safe as consolidation chemotherapy for risk-tailored patients with acute promyelocytic leukemia: multicenter experience.
Topics: Adolescent; Adult; Aged; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Arsenic Trioxide; Arsenicals; Consolidation Chemotherapy; Cytarabine; Daunorubicin; Disease-Free Survival; Female; Humans; Kaplan-Meier Estimate; Leukemia, Promyelocytic, Acute; Male; Middle Aged; Oxides; Tretinoin; Young Adult | 2012 |
Disease-stabilizing treatment with all-trans retinoic acid and valproic acid in acute myeloid leukemia: serum hsp70 and hsp90 levels and serum cytokine profiles are determined by the disease, patient age, and anti-leukemic treatment.
Topics: Adult; Age Factors; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Cytarabine; Cytokines; Female; HSP70 Heat-Shock Proteins; HSP90 Heat-Shock Proteins; Humans; Leukemia, Myeloid, Acute; Leukemia, Myelomonocytic, Acute; Male; Middle Aged; Neoplasm Proteins; Palliative Care; Prognosis; Theophylline; Tretinoin; Tumor Cells, Cultured; Valproic Acid | 2012 |
Recombinant human soluble thrombomodulin safely and effectively rescues acute promyelocytic leukemia patients from disseminated intravascular coagulation.
Topics: Antineoplastic Combined Chemotherapy Protocols; Cytarabine; Disseminated Intravascular Coagulation; Female; Humans; Kaplan-Meier Estimate; Leukemia, Promyelocytic, Acute; Male; Middle Aged; Recombinant Proteins; Thrombomodulin; Tretinoin | 2012 |
Long-term follow-up of European APL 2000 trial, evaluating the role of cytarabine combined with ATRA and Daunorubicin in the treatment of nonelderly APL patients.
Topics: Antineoplastic Combined Chemotherapy Protocols; Cytarabine; Daunorubicin; Early Termination of Clinical Trials; Female; Follow-Up Studies; Humans; Leukemia, Promyelocytic, Acute; Male; Middle Aged; Recurrence; Risk Factors; Treatment Outcome; Tretinoin | 2013 |
Expression of CD56 is an unfavorable prognostic factor for acute promyelocytic leukemia with higher initial white blood cell counts.
Topics: Adolescent; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; CD56 Antigen; Cytarabine; Disease-Free Survival; Female; Humans; Idarubicin; Leukemia, Promyelocytic, Acute; Leukocyte Count; Male; Middle Aged; Neoplasm Recurrence, Local; Platelet Count; Prognosis; Prospective Studies; Remission Induction; Treatment Outcome; Tretinoin; Young Adult | 2014 |
Phase I study of cladribine, cytarabine, granulocyte colony stimulating factor (CLAG regimen) and midostaurin and all-trans retinoic acid in relapsed/refractory AML.
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Cladribine; Cytarabine; Female; fms-Like Tyrosine Kinase 3; Granulocyte Colony-Stimulating Factor; Humans; Leukemia, Myeloid, Acute; Male; Middle Aged; Mutation; Nuclear Proteins; Nucleophosmin; Recurrence; Remission Induction; Staurosporine; Treatment Outcome; Tretinoin | 2014 |
Arsenic trioxide during consolidation for patients with previously untreated low/intermediate risk acute promyelocytic leukaemia may eliminate the need for maintenance therapy.
Topics: Adult; Aged; Aminoglycosides; Animals; Antibodies, Monoclonal, Humanized; Antineoplastic Combined Chemotherapy Protocols; Arsenic Trioxide; Arsenicals; Biomarkers, Tumor; Consolidation Chemotherapy; Cytarabine; Daunorubicin; Disease-Free Survival; Dogs; Female; Gemtuzumab; Humans; Leukemia, Promyelocytic, Acute; Maintenance Chemotherapy; Male; Mercaptopurine; Methotrexate; Middle Aged; Oncogene Proteins, Fusion; Oxides; Platelet Count; Remission Induction; Risk; Treatment Outcome; Tretinoin; Young Adult | 2014 |
Valproic acid in combination with all-trans retinoic acid and intensive therapy for acute myeloid leukemia in older patients.
Topics: Aged; Aged, 80 and over; Antineoplastic Agents; Critical Care; Cytarabine; Disease-Free Survival; Drug Synergism; Enzyme Inhibitors; Female; Follow-Up Studies; Humans; Idarubicin; Leukemia, Myeloid, Acute; Male; Middle Aged; Mutation; Nuclear Proteins; Nucleophosmin; Survival Rate; Tretinoin; Valproic Acid | 2014 |
Salvage therapy with high-dose cytarabine and mitoxantrone in combination with all-trans retinoic acid and gemtuzumab ozogamicin in acute myeloid leukemia refractory to first induction therapy.
Topics: Adult; Aminoglycosides; Antibodies, Monoclonal, Humanized; Antineoplastic Combined Chemotherapy Protocols; Comorbidity; Consolidation Chemotherapy; Cytarabine; Female; Gemtuzumab; Hematopoietic Stem Cell Transplantation; Humans; Kaplan-Meier Estimate; Leukemia, Myeloid, Acute; Male; Middle Aged; Mitoxantrone; Remission Induction; Salvage Therapy; Treatment Outcome; Tretinoin; Young Adult | 2016 |
Frontline therapy of acute promyelocytic leukemia: Randomized comparison of ATRA and intensified chemotherapy versus ATRA and anthracyclines.
Topics: Adult; Aged; Aged, 80 and over; Anthracyclines; Antineoplastic Combined Chemotherapy Protocols; Biomarkers; Consolidation Chemotherapy; Cytarabine; Cytogenetic Analysis; Female; Humans; Leukemia, Promyelocytic, Acute; Male; Middle Aged; Neoplasm, Residual; Recurrence; Remission Induction; Survival Analysis; Treatment Outcome; Tretinoin; Young Adult | 2018 |
Role of cytarabine in paediatric acute promyelocytic leukemia treated with the combination of all-trans retinoic acid and arsenic trioxide: a randomized controlled trial.
Topics: Adolescent; Antineoplastic Combined Chemotherapy Protocols; Arsenic Trioxide; Biomarkers; Case-Control Studies; Child; Child, Preschool; Consolidation Chemotherapy; Cytarabine; Female; Humans; Induction Chemotherapy; Leukemia, Promyelocytic, Acute; Male; Treatment Outcome; Tretinoin | 2018 |
Outcome for pediatric acute promyelocytic leukemia patients at Children's Oncology Group sites on the Leukemia Intergroup Study CALGB 9710 (Alliance).
Topics: Adolescent; Antineoplastic Combined Chemotherapy Protocols; Child; Child, Preschool; Cytarabine; Daunorubicin; Female; Follow-Up Studies; Humans; Infant; Infant, Newborn; Leukemia, Promyelocytic, Acute; Male; Prognosis; Survival Rate; Tretinoin | 2019 |
Gemtuzumab Ozogamicin in
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Antineoplastic Agents, Immunological; Antineoplastic Combined Chemotherapy Protocols; Consolidation Chemotherapy; Cytarabine; Etoposide; Female; Gemtuzumab; Humans; Idarubicin; Induction Chemotherapy; Leukemia, Myeloid, Acute; Male; Middle Aged; Mutation; Nuclear Proteins; Nucleophosmin; Progression-Free Survival; Prospective Studies; Tretinoin; Young Adult | 2020 |
Intensive chemotherapy with or without gemtuzumab ozogamicin in patients with NPM1-mutated acute myeloid leukaemia (AMLSG 09-09): a randomised, open-label, multicentre, phase 3 trial.
Topics: Adolescent; Adult; Antineoplastic Combined Chemotherapy Protocols; Cytarabine; Female; Gemtuzumab; Humans; Leukemia, Myeloid, Acute; Male; Middle Aged; Neoplasm Recurrence, Local; Nuclear Proteins; Treatment Outcome; Tretinoin; Young Adult | 2023 |
Homoharringtonine-Based Induction Regimen Improved the Remission Rate and Survival Rate in Chinese Childhood AML: A Report From the CCLG-AML 2015 Protocol Study.
Topics: Antineoplastic Combined Chemotherapy Protocols; Child; Cytarabine; East Asian People; Homoharringtonine; Humans; Leukemia, Promyelocytic, Acute; Multicenter Studies as Topic; Remission Induction; Survival Rate; Treatment Outcome; Tretinoin | 2023 |
210 other study(ies) available for cytarabine and tretinoin
Article | Year |
---|---|
Retinoic acid conjugates as potential antitumor agents: synthesis and biological activity of conjugates with Ara-A, Ara-C, 3(2H)-furanone, and aniline mustard moieties.
Topics: Aniline Mustard; Antineoplastic Agents; Cell Differentiation; Cytarabine; Drug Carriers; Furans; HL-60 Cells; Humans; Hydrolysis; Nucleosides; Tretinoin; Vidarabine | 1997 |
Assessment of the health effects of chemicals in humans: II. Construction of an adverse effects database for QSAR modeling.
Topics: Adverse Drug Reaction Reporting Systems; Artificial Intelligence; Computers; Databases, Factual; Drug Prescriptions; Drug-Related Side Effects and Adverse Reactions; Endpoint Determination; Models, Molecular; Quantitative Structure-Activity Relationship; Software; United States; United States Food and Drug Administration | 2004 |
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship | 2010 |
Preclinical strategy to reduce clinical hepatotoxicity using in vitro bioactivation data for >200 compounds.
Topics: Chemical and Drug Induced Liver Injury; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Decision Trees; Drug Evaluation, Preclinical; Drug-Related Side Effects and Adverse Reactions; Glutathione; Humans; Liver; Pharmaceutical Preparations; Protein Binding | 2012 |
A multifactorial approach to hepatobiliary transporter assessment enables improved therapeutic compound development.
Topics: Animals; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Transport; Chemical and Drug Induced Liver Injury; Cluster Analysis; Drug-Related Side Effects and Adverse Reactions; Humans; Liver; Male; Multidrug Resistance-Associated Proteins; Pharmacokinetics; Rats; Rats, Sprague-Dawley; Recombinant Proteins; Risk Assessment; Risk Factors; Toxicity Tests | 2013 |
"Chemical surgery" as an approach to study morphogenetic events in embryonic mouse limb.
Topics: Abnormalities, Drug-Induced; Animals; Cartilage; Cell Cycle; Cell Survival; Cytarabine; Extremities; Gestational Age; Limb Deformities, Congenital; Mice; Morphogenesis; Tretinoin; Vitamin A | 1977 |
Vimentin expression as a late event in the in vitro differentiation of human promonocytic cells.
Topics: Amsacrine; Antigens, CD; Bucladesine; Butyrates; Butyric Acid; CD11 Antigens; Cell Adhesion; Cell Differentiation; Cells, Cultured; Cytarabine; Humans; Monocytes; Phorbol Esters; Protein Biosynthesis; Stem Cells; Transcription, Genetic; Tretinoin; Vimentin | 1992 |
A combined evaluation of biochemical and morphological changes during human neuroblastoma cell differentiation.
Topics: Biomarkers, Tumor; Catecholamines; Cell Differentiation; Cytarabine; Gene Expression Regulation, Neoplastic; Humans; Interferon-gamma; Neoplasm Proteins; Nerve Growth Factors; Nerve Tissue Proteins; Neuroblastoma; Neuropeptides; Neurotransmitter Agents; Tetradecanoylphorbol Acetate; Tretinoin; Tumor Cells, Cultured; Tumor Necrosis Factor-alpha | 1992 |
Therapy of 'high risk' myelodysplastic syndromes with an association of low-dose Ara-C, retinoic acid and 1,25-dihydroxyvitamin D3.
Topics: Aged; Aged, 80 and over; Calcitriol; Cytarabine; Drug Therapy, Combination; Female; Humans; Male; Middle Aged; Myelodysplastic Syndromes; Prospective Studies; Risk Factors; Tretinoin | 1992 |
Proof of differentiative mode of action of all-trans retinoic acid in acute promyelocytic leukemia using X-linked clonal analysis.
Topics: Adolescent; Antineoplastic Combined Chemotherapy Protocols; Blotting, Southern; Bone Marrow; Chromosome Aberrations; Chromosome Disorders; Chromosomes, Human, Pair 15; Chromosomes, Human, Pair 17; Clone Cells; Cytarabine; Daunorubicin; DNA, Neoplasm; Etoposide; Female; Genetic Linkage; Humans; Leukemia, Promyelocytic, Acute; Translocation, Genetic; Tretinoin; X Chromosome | 1992 |
Comparison of the effects of all-trans and cis-retinoic acid on the blast stem cells of acute myeloblastic leukemia in culture.
Topics: Cell Survival; Cytarabine; Drug Administration Schedule; In Vitro Techniques; Leukemia, Myeloid, Acute; Neoplastic Stem Cells; Stereoisomerism; Tretinoin; Tumor Cells, Cultured | 1992 |
Multiparameter assessment of the cell cycle effects of bioactive and cytotoxic agents.
Topics: Animals; Bone Marrow; Bromodeoxyuridine; Cell Cycle; Cell Nucleus; Cell Survival; Cells, Cultured; Chickens; Cytarabine; DNA Replication; DNA, Neoplasm; G1 Phase; G2 Phase; Interferon alpha-2; Interferon-alpha; Kinetics; Leukemia, Myelogenous, Chronic, BCR-ABL Positive; Leukemia, Myeloid, Acute; Mitosis; Propidium; Recombinant Proteins; S Phase; Tretinoin; Tumor Cells, Cultured | 1992 |
OCI/AML-4 an acute myeloblastic leukemia cell line: regulation and response to cytosine arabinoside.
Topics: Antigens, CD; Blotting, Northern; Cell Division; Cell Survival; Cytarabine; Gene Expression; Granulocyte Colony-Stimulating Factor; Granulocyte-Macrophage Colony-Stimulating Factor; Hematopoietic Cell Growth Factors; Humans; Hydrocortisone; In Vitro Techniques; Interleukin-3; Interleukin-6; Leukemia, Myeloid, Acute; Macrophage Colony-Stimulating Factor; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-kit; Receptor, Macrophage Colony-Stimulating Factor; Stem Cell Factor; Tretinoin; Tumor Cells, Cultured | 1991 |
Gamma-interferon, retinoic acid, and cytosine arabinoside induce neuroblastoma differentiation by different mechanisms.
Topics: Antigens, Neoplasm; Biomarkers, Tumor; Cell Differentiation; Cytarabine; Cytoskeletal Proteins; DNA Polymerase I; Dose-Response Relationship, Drug; Humans; Inositol Phosphates; Interferon-gamma; Neoplasm Proteins; Neuroblastoma; Stimulation, Chemical; Tretinoin; Tumor Cells, Cultured | 1991 |
New synergistic combinations of differentiation inducing agents in the treatment of acute myeloid leukaemia.
Topics: Acetamides; Antineoplastic Combined Chemotherapy Protocols; Cell Differentiation; Cytarabine; Drug Synergism; Humans; Leukemia, Myeloid; Tretinoin; Tumor Cells, Cultured | 1991 |
Response to trans-retinoic acid in an AMLM3 patient resistant to cis-retinoic acid.
Topics: Antineoplastic Combined Chemotherapy Protocols; Cytarabine; Daunorubicin; Etoposide; Humans; Leukemia, Promyelocytic, Acute; Lomustine; Male; Middle Aged; Stereoisomerism; Tretinoin | 1991 |
The recombination activating gene-1 (RAG-1) transcript is present in the murine central nervous system.
Topics: Aging; Animals; Base Sequence; Brain; Cell Division; Cell Line; Chromosome Mapping; Cytarabine; Genes; Mice; Mice, Inbred BALB C; Molecular Sequence Data; Neurons; Nucleic Acid Hybridization; Oligonucleotide Probes; Organ Specificity; Polymerase Chain Reaction; Recombination, Genetic; RNA Probes; Teratoma; Transcription, Genetic; Tretinoin | 1991 |
Retinoids increase perinatal spinal cord neuronal survival and astroglial differentiation.
Topics: Animals; Astrocytes; Cell Differentiation; Cell Division; Cell Survival; Cells, Cultured; Cytarabine; Embryo, Mammalian; Fluorescent Antibody Technique; Kinetics; Neurons; Phosphopyruvate Hydratase; Rats; Rats, Inbred Strains; Spinal Cord; Tretinoin; Vitamin A | 1990 |
Triple combination of retinoic acid, low concentration of cytarabine and dimethylformamide induces differentiation of human acute myeloid leukaemic blasts.
Topics: Antineoplastic Combined Chemotherapy Protocols; Cell Transformation, Neoplastic; Cytarabine; Dimethylformamide; Humans; Leukemia, Myeloid, Acute; Tretinoin | 1990 |
Cell cycle related change of Ara-C transport in HL-60 cells after differentiation induction.
Topics: Aphidicolin; Biological Transport; Cell Cycle; Cell Differentiation; Cell Membrane; Cytarabine; Deoxycytidine Kinase; Diterpenes; Humans; Interphase; Leukemia, Promyelocytic, Acute; Mutation; Tretinoin; Tumor Cells, Cultured | 1989 |
Maturation induction in freshly isolated human myeloid leukemic cells, 1.25 (OH)2 vitamin D3 being the most potent inducer.
Topics: Adult; Aged; Cell Differentiation; Cell Separation; Cholecalciferol; Cytarabine; Dimethyl Sulfoxide; Female; Granulocytes; Humans; Leukemia, Myeloid, Acute; Male; Middle Aged; Monocytes; Neoplastic Stem Cells; Tretinoin; Tumor Cells, Cultured | 1989 |
Reduction of ara-C cytotoxicity in HL 60 cells by addition of deoxycytidine, cytidine or increased level of cytidine deaminase.
Topics: Bone Marrow; Bone Marrow Cells; Cell Division; Cytarabine; Cytidine; Cytidine Deaminase; Deoxycytidine; Deoxycytidine Kinase; Humans; Leukemia, Promyelocytic, Acute; Nucleoside Deaminases; Phosphotransferases; Tetrahydrouridine; Tretinoin; Tumor Cells, Cultured | 1989 |
Characterization of nucleoside transport during leukemic cell differentiation.
Topics: Biological Transport; Cell Differentiation; Cytarabine; Deoxycytidine Kinase; Dipyridamole; Humans; Inosine; Leukemia, Promyelocytic, Acute; Precursor Cell Lymphoblastic Leukemia-Lymphoma; T-Lymphocytes; Tetradecanoylphorbol Acetate; Thioinosine; Tretinoin; Tumor Cells, Cultured | 1989 |
Effects of retinoic acid, 1,25-dihydroxyvitamin D3, cytosine arabinoside and alpha-interferon on bone marrow cells from patients with myelodysplastic syndromes.
Topics: Bone Marrow; Calcitriol; Cell Differentiation; Cell Division; Colony-Forming Units Assay; Cytarabine; DNA; Humans; In Vitro Techniques; Interferon Type I; Myelodysplastic Syndromes; Tretinoin | 1989 |
Interaction between retinoic acid and cytosine arabinoside affecting the blast cells of acute myeloblastic leukemia.
Topics: Cell Survival; Cytarabine; DNA; Doxorubicin; Drug Interactions; Leukemia, Myeloid, Acute; Neoplastic Stem Cells; Tretinoin; Tumor Cells, Cultured | 1989 |
Treatment for myelodysplastic syndromes.
Topics: Cytarabine; Drug Therapy, Combination; Humans; Isotretinoin; Myelodysplastic Syndromes; Tretinoin | 1987 |
Changes in the expression of N-acetylglucosaminyltransferase III, IV, V associated with the differentiation of HL-60 cells.
Topics: Calcitriol; Carbohydrate Conformation; Carbohydrate Sequence; Cell Differentiation; Cell Line; Cytarabine; Dimethyl Sulfoxide; Glucosyltransferases; Humans; N-Acetylglucosaminyltransferases; Oligosaccharides; Tretinoin | 1987 |
Induction of basophilic differentiation in the human basophilic cell line KU812.
Topics: Antigens, Differentiation, B-Lymphocyte; Basophils; Butyrates; Butyric Acid; Cell Differentiation; Cell Line; Culture Media; Cytarabine; Dimethyl Sulfoxide; Growth Substances; Humans; Immunoglobulin E; Interferon-gamma; Receptors, Fc; Receptors, IgE; Tetradecanoylphorbol Acetate; Tretinoin | 1988 |
Acute myelogenous leukemia of unfavourable prognosis treated with retinoic acid, vitamin D3, alpha-interferon and low doses of cytosine arabinoside.
Topics: Aged; Bone Marrow; Child; Cholecalciferol; Combined Modality Therapy; Cytarabine; Female; Follow-Up Studies; Humans; Interferon Type I; Leukemia, Myeloid, Acute; Male; Middle Aged; Prognosis; Tretinoin | 1986 |
Differentiation of TERA-2 human embryonal carcinoma cells into neurons and HCMV permissive cells. Induction by agents other than retinoic acid.
Topics: Acetamides; Bromodeoxyuridine; Butyrates; Butyric Acid; Cell Differentiation; Cell Line; Cisplatin; Clone Cells; Cyclic AMP; Cytarabine; Dimethyl Sulfoxide; Humans; Idoxuridine; Kinetics; Neurons; Teratoma; Tetradecanoylphorbol Acetate; Tretinoin | 1986 |
All-trans retinoic acid with or without low dose cytosine arabinoside in acute promyelocytic leukemia. Report of 6 cases.
Topics: Adult; Child; Child, Preschool; Cytarabine; Female; Humans; Leukemia, Myeloid, Acute; Male; Middle Aged; Tretinoin | 1987 |
Heterogeneity of the response to inducers of differentiation and to cytostatics of tumor cell populations.
Topics: Antineoplastic Agents; Cell Differentiation; Cisplatin; Cytarabine; Dacarbazine; Dimethyl Sulfoxide; Dose-Response Relationship, Drug; Doxorubicin; Fluorouracil; Humans; Leukemia, Erythroblastic, Acute; Leukemia, Promyelocytic, Acute; Melanoma; Neoplasms; Tetradecanoylphorbol Acetate; Tretinoin; Tumor Cells, Cultured | 1988 |
Therapeutic effects of low-dose cytosine arabinoside, alpha-interferon, 1 alpha-hydroxyvitamin D3 and retinoic acid in acute leukemia and myelodysplastic syndromes.
Topics: Actuarial Analysis; Acute Disease; Adolescent; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Cytarabine; Drug Administration Schedule; Female; Humans; Hydroxycholecalciferols; Interferon Type I; Leukemia; Male; Middle Aged; Myelodysplastic Syndromes; Remission Induction; Tretinoin | 1988 |
The role of 13 cis-retinoic acid in the remission induction of a patient with acute promyelocytic leukemia.
Topics: Adult; Cell Differentiation; Cytarabine; Humans; In Vitro Techniques; Isotretinoin; Leukemia, Myeloid, Acute; Male; Tretinoin | 1986 |
1-B-D arabinofuranosyl cytosine and all-trans retinoic acid in combination accelerates and increases monocyte differentiation of myeloid leukemic cells.
Topics: Antibodies, Monoclonal; Cell Differentiation; Cell Line; Cells, Cultured; Cytarabine; Dose-Response Relationship, Drug; Drug Administration Schedule; Drug Synergism; Humans; In Vitro Techniques; Isomerism; Leukemia, Myeloid, Acute; Nitroblue Tetrazolium; Tretinoin | 1986 |
[Treatment of acute promyelocytic leukemia by retinoic acid with or without low dose cytosine arabinoside: report of 4 cases].
Topics: Cytarabine; Drug Therapy, Combination; Humans; Leukemia, Myeloid, Acute; Tretinoin | 1987 |
Differentiation induction in myelodysplasia and acute myeloid leukaemia: use of synergistic drug combinations.
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Bone Marrow; Cell Differentiation; Cytarabine; Drug Synergism; Female; Humans; Karyotyping; Leukemia, Myeloid, Acute; Male; Middle Aged; Myelodysplastic Syndromes; Thioguanine; Tretinoin; Tumor Cells, Cultured; Vincristine | 1987 |
Effects of 1-beta-D-arabinofuranosylcytosine on proto-oncogene expression in human U-937 cells.
Topics: Actins; Cell Division; Cell Line; Cytarabine; Humans; Leukemia; Proto-Oncogene Mas; Proto-Oncogene Proteins; Proto-Oncogenes; Transcription, Genetic; Tretinoin | 1986 |
13-cis-Retinoic acid does not increase the true remission rate and the duration of true remission (induced by cytotoxic chemotherapy) in patients with chronic phase chronic myelogenous leukemia.
Topics: Adolescent; Adult; Antineoplastic Combined Chemotherapy Protocols; Bone Marrow; Chromosomes, Human, 21-22 and Y; Cytarabine; Daunorubicin; Humans; Isotretinoin; Leukemia, Myeloid; Leukopenia; Liver; Middle Aged; Stomatitis; Thioguanine; Thrombocytopenia; Time Factors; Tretinoin | 1985 |
Drug association including ara-C in myeloid leukemia cell differentiation: in vitro studies.
Topics: Cell Differentiation; Cell Line; Cytarabine; Drug Synergism; Humans; Kinetics; Leukemia, Monocytic, Acute; Leukemia, Myeloid; Tretinoin | 1985 |
Effects of 13-cis retinoic acid and Ara-C on differentiation and proliferation of non-promyelocytic acute myelogenous leukemia.
Topics: Adult; Aged; Alkaline Phosphatase; Cell Differentiation; Cell Division; Cytarabine; Female; Humans; Isotretinoin; Leukemia, Myeloid, Acute; Leukocytes; Male; Middle Aged; Thymidine; Tretinoin; Tritium | 1985 |
Synergistic interaction between differentiation inducers and DNA synthesis inhibitors: a new approach to differentiation induction in myelodysplasia and acute myeloid leukaemia.
Topics: Antineoplastic Combined Chemotherapy Protocols; Aphidicolin; Bone Marrow; Bone Marrow Diseases; Cell Differentiation; Cells, Cultured; Cytarabine; Diterpenes; DNA; Drug Synergism; Formamides; Humans; Leukemia, Myeloid, Acute; Mercaptopurine; Preleukemia; Syndrome; Tretinoin | 1985 |
Differentiation in myelodysplastic, myeloid leukaemic and normal haemopoietic cells: a new approach exploiting the synergistic interaction between differentiation inducers and DNA synthesis inhibitors.
Topics: Antineoplastic Agents; Aphidicolin; Bone Marrow; Bone Marrow Cells; Cell Differentiation; Cells, Cultured; Cytarabine; Diterpenes; DNA Replication; Formamides; Hematopoietic Stem Cells; Humans; Leukemia, Myeloid; Mercaptopurine; Myeloproliferative Disorders; Reference Values; Tretinoin | 1985 |
Effect of antimetabolites and thymidine blockage on the induction of differentiation of HL-60 cells by retinoic acid or 1 alpha,25-dihydroxyvitamin D3.
Topics: Antibiotics, Antineoplastic; Aphidicolin; Calcitriol; Cell Differentiation; Cell Division; Cell Line; Cytarabine; Diterpenes; DNA Replication; Humans; Hydroxyurea; Kinetics; Leukemia, Myeloid, Acute; Tretinoin | 1985 |
Macromolecular and cell cycle effects of different classes of agents inducing the maturation of human myeloblastic leukemia (ML-1) cells.
Topics: Cell Cycle; Cell Differentiation; Cell Line; Cycloheximide; Cytarabine; Dactinomycin; Daunorubicin; DNA Replication; Humans; Kinetics; Leucine; Leukemia, Myeloid, Acute; Protein Biosynthesis; Thymidine; Transcription, Genetic; Tretinoin; Tritium; Uridine | 1984 |
Potentiated maturation with a high proliferating activity of acute promyelocytic leukemia induced in vitro by granulocyte or granulocyte/macrophage colony-stimulating factors in combination with all-trans retinoic acid.
Topics: Adolescent; Adult; Bone Marrow; Cell Division; Chemotaxis; Child, Preschool; Cytarabine; Drug Interactions; Female; Granulocyte Colony-Stimulating Factor; Granulocyte-Macrophage Colony-Stimulating Factor; Humans; Leukemia, Promyelocytic, Acute; Male; Middle Aged; Recombinant Proteins; Remission Induction; Tretinoin; Tumor Cells, Cultured | 1994 |
All-trans retinoic acid potentiates megakaryocyte colony formation: in vitro and in vivo effects after administration to acute promyelocytic leukemia patients.
Topics: Antigens, CD; Antigens, CD34; Antineoplastic Combined Chemotherapy Protocols; Bone Marrow; Bone Marrow Cells; Colony-Forming Units Assay; Cytarabine; Daunorubicin; Hematopoietic Stem Cells; Humans; Leukemia, Myeloid, Acute; Leukemia, Promyelocytic, Acute; Megakaryocytes; Tretinoin | 1994 |
Direct evidence for the participation of bcl-2 in the regulation by retinoic acid of the Ara-C sensitivity of leukemic stem cells.
Topics: Acute Disease; Antineoplastic Agents; Cell Survival; Cytarabine; Drug Resistance, Neoplasm; Humans; Hydrogen Peroxide; Leukemia, Myeloid; Oncogenes; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-bcl-2; Transfection; Tretinoin; Tumor Cells, Cultured; Tumor Stem Cell Assay | 1995 |
Influence of schedule on regulated sensitivity of AML blasts to cytosine arabinoside.
Topics: Acute Disease; Aged; Cell Survival; Cytarabine; Female; Granulocyte Colony-Stimulating Factor; Granulocyte-Macrophage Colony-Stimulating Factor; Humans; In Vitro Techniques; Leukemia, Myeloid; Male; Methylcellulose; Middle Aged; Tretinoin; Tumor Cells, Cultured | 1993 |
[Comparison of the sensitivity of retinoic acid sensitive and resistant HL-60 cell lines to several anti-leukemia drugs].
Topics: Antineoplastic Agents; Cell Transformation, Neoplastic; Cytarabine; Drug Resistance; Drug Synergism; Harringtonines; Humans; Leukemia, Promyelocytic, Acute; Tretinoin; Tumor Cells, Cultured | 1994 |
Rapid progression of 'retinoic acid syndrome' in the hypogranular variant of acute promyelocytic leukaemia, despite treatment with dexamethasone and conventional chemotherapy.
Topics: Acute Kidney Injury; Adult; Antineoplastic Combined Chemotherapy Protocols; Cerebral Hemorrhage; Combined Modality Therapy; Cytarabine; Daunorubicin; Dexamethasone; Disease Progression; Fatal Outcome; Female; Humans; Leukemia, Promyelocytic, Acute; Leukocytosis; Renal Dialysis; Respiration, Artificial; Respiratory Insufficiency; Syndrome; Tretinoin | 1994 |
Acute colonic pseudo-obstruction (Ogilvie's syndrome) during induction treatment with chemotherapy and all-trans-retinoic acid for acute promyelocytic leukemia.
Topics: Antineoplastic Combined Chemotherapy Protocols; Colonic Pseudo-Obstruction; Cytarabine; Daunorubicin; Female; Fever; Humans; Leukemia, Promyelocytic, Acute; Leukocyte Count; Middle Aged; Remission Induction; Tretinoin | 1995 |
Mechanism of cytosine arabinoside toxicity to the blast cells of acute myeloblastic leukemia: involvement of free radicals.
Topics: Acetylcysteine; Antioxidants; Base Sequence; Blotting, Northern; Cytarabine; Down-Regulation; Drug Interactions; Drug Screening Assays, Antitumor; Free Radicals; Gene Expression Regulation, Leukemic; Humans; Hydrocortisone; Hydrogen Peroxide; Leukemia, Myeloid, Acute; Lymphocyte Activation; Lymphocytes; Molecular Sequence Data; Polymerase Chain Reaction; Proto-Oncogene Mas; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-bcl-2; Transcription, Genetic; Tretinoin; Tumor Cells, Cultured | 1995 |
Fluorescence-labeling of nicks in DNA from leukemic blast cells as a measure of damage following cytosine arabinoside. Application to the study of regulated drug sensitivity.
Topics: Cytarabine; DNA Damage; DNA Repair; DNA, Neoplasm; Drug Screening Assays, Antitumor; Flow Cytometry; Fluorescence; Genetic Techniques; Humans; Hydrocortisone; Kinetics; Leukemia, Myeloid, Acute; Tretinoin; Tumor Cells, Cultured; Tumor Stem Cell Assay | 1994 |
Regulation by retinoic acid and hydrocortisone of the anthracycline sensitivity of blast cells of acute myeloblastic leukemia.
Topics: Adult; Aged; Cell Survival; Cytarabine; Daunorubicin; DNA Damage; DNA Repair; DNA, Neoplasm; Dose-Response Relationship, Drug; Female; Genetic Techniques; Humans; Hydrocortisone; Kinetics; Leukemia, Myeloid, Acute; Male; Middle Aged; Tretinoin; Tumor Cells, Cultured; Tumor Stem Cell Assay | 1994 |
Aggressive chemotherapy for acute leukemia relapsed after transplantation.
Topics: Adolescent; Adult; Antineoplastic Combined Chemotherapy Protocols; Bone Marrow Transplantation; Cytarabine; Female; Humans; Idarubicin; Italy; Leukemia, Myeloid, Acute; Leukemia, Myelomonocytic, Acute; Male; Middle Aged; Neoplasm, Residual; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Prednisone; Remission Induction; Retrospective Studies; Salvage Therapy; Survival Analysis; Treatment Outcome; Tretinoin; Vincristine | 1994 |
Sequential targeted therapy for relapsed acute promyelocytic leukemia with all-trans retinoic acid and anti-CD33 monoclonal antibody M195.
Topics: Adult; Aged; Antibodies, Monoclonal; Antigens, CD; Antigens, Differentiation, Myelomonocytic; Antineoplastic Combined Chemotherapy Protocols; Biomarkers, Tumor; Cell Differentiation; Combined Modality Therapy; Cytarabine; Daunorubicin; Disease-Free Survival; Female; Humans; Idarubicin; Immunologic Factors; Leukemia, Promyelocytic, Acute; Life Tables; Male; Middle Aged; Neoplasm Proteins; Neoplasm, Residual; Neutropenia; Nuclear Proteins; Oncogene Proteins, Fusion; Polymerase Chain Reaction; Promyelocytic Leukemia Protein; Receptors, Retinoic Acid; Remission Induction; Salvage Therapy; Sialic Acid Binding Ig-like Lectin 3; Survival Analysis; Transcription Factors; Treatment Outcome; Tretinoin; Tumor Suppressor Proteins | 1995 |
Toxicity of tretinoin in acute promyelocytic leukaemia.
Topics: Child, Preschool; Cytarabine; Female; Humans; Leukemia, Promyelocytic, Acute; Leukocyte Count; Leukocytosis; Papilledema; Remission Induction; Tretinoin | 1994 |
Retinoic acid is required for and potentiates differentiation of acute promyelocytic leukemia cells by nonretinoid agents.
Topics: Acetamides; Butyrates; Cell Differentiation; Cholecalciferol; Cytarabine; Drug Synergism; Humans; In Vitro Techniques; Leukemia, Promyelocytic, Acute; Tretinoin; Tumor Cells, Cultured | 1994 |
[Complete remission in acute promyelocytic leukemia. The advantages of all-trans-retinoic acid compared to conventional chemotherapy].
Topics: Adult; Aminoglutethimide; Antineoplastic Combined Chemotherapy Protocols; Bone Marrow; Cytarabine; Danazol; Drug Evaluation; Female; Humans; Leukemia, Promyelocytic, Acute; Male; Middle Aged; Mitoxantrone; Prognosis; Remission Induction; Tamoxifen; Time Factors; Tretinoin | 1994 |
Many chick embryo limb mesoderm cells require b-FGF for survival.
Topics: 3T3 Cells; Animals; Apoptosis; Cell Survival; Chick Embryo; Cytarabine; Ectoderm; Extremities; Fibroblast Growth Factor 2; HeLa Cells; Humans; Mesoderm; Mice; Suramin; Tretinoin | 1993 |
[Acute promyelocytic leukemia (APL) resulting in broad cerebral infarction during all-trans retinoic acid (ATRA) treatment].
Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; Cerebral Infarction; Cytarabine; Daunorubicin; Female; Humans; Leukemia, Promyelocytic, Acute; Tretinoin | 1994 |
Treatment of refractory undifferentiated acute myelogenous leukemia with all-trans-retinoic acid.
Topics: Aged; Base Sequence; Biopsy; Bone Marrow; Cytarabine; Daunorubicin; Female; Humans; Leukemia, Myeloid, Acute; Molecular Sequence Data; Remission Induction; Tretinoin | 1994 |
H and L ferritin gene expression in U937 cells induced to macrophage differentiation.
Topics: Antigens, CD; Cell Differentiation; Cell Line; Cytarabine; Ferritins; Gene Expression; HLA-DR Antigens; Humans; Lymphoma, Large B-Cell, Diffuse; Macromolecular Substances; Macrophages; RNA, Messenger; Tetradecanoylphorbol Acetate; Tretinoin; Tumor Cells, Cultured | 1993 |
[Treatment of myelodysplastic syndrome by combined traditional Chinese medicine and Western medicine therapy].
Topics: Adolescent; Adult; Aged; Cell Transformation, Neoplastic; Cytarabine; Drugs, Chinese Herbal; Female; Humans; Leukemia, Myeloid, Acute; Male; Middle Aged; Myelodysplastic Syndromes; Pyridoxine; Stanozolol; Tretinoin | 1993 |
Repeated complete remission in a patient with acute promyelocytic leukemia after treatment with 13-cis-retinoic acid first and with all-trans-retinoic acid in relapse.
Topics: Antineoplastic Combined Chemotherapy Protocols; Cytarabine; Daunorubicin; Female; Humans; Isotretinoin; Leukemia, Promyelocytic, Acute; Middle Aged; Recurrence; Remission Induction; Tretinoin | 1993 |
Expression of the met/hepatocyte growth factor/scatter factor receptor and its ligand during differentiation of murine P19 embryonal carcinoma cells.
Topics: Animals; Base Sequence; Cell Differentiation; Cytarabine; Dimethyl Sulfoxide; Drug Combinations; Ectoderm; Embryonal Carcinoma Stem Cells; Ligands; Mesoderm; Mice; Molecular Sequence Data; Neoplastic Stem Cells; Neurons; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-met; Receptors, Cell Surface; RNA, Messenger; Signal Transduction; Tretinoin | 1993 |
Differential modulation of the expression of the intermediate filament proteins vimentin and nuclear lamins A and C by differentiation inducers in human myeloid leukemia (U-937, HL-60) cells.
Topics: Bucladesine; Butyrates; Butyric Acid; Cell Differentiation; Cytarabine; Gene Expression; Humans; In Vitro Techniques; Lamins; Leukemia, Myeloid; Nuclear Proteins; RNA, Messenger; Tetradecanoylphorbol Acetate; Tretinoin; Tumor Cells, Cultured; Vimentin | 1993 |
All-trans retinoic acid plus low doses of cytarabine for the treatment of "poor-risk" acute myeloid leukemias.
Topics: Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Bone Marrow; Cytarabine; Female; Humans; Leukemia, Myeloid, Acute; Male; Middle Aged; Remission Induction; Tretinoin | 1993 |
Retinoic acid stimulates regeneration of mammalian auditory hair cells.
Topics: Animals; Cytarabine; Hair Cells, Auditory; Microscopy, Electron; Neomycin; Organ Culture Techniques; Organ of Corti; Rats; Regeneration; Tretinoin | 1993 |
t(15;17) hypergranular acute promyelocytic leukemia (M3) developing into a t(3;6) M3 without t(15;17) at relapse.
Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; Bone Marrow; Chromosome Mapping; Chromosomes, Human, Pair 15; Chromosomes, Human, Pair 17; Chromosomes, Human, Pair 3; Chromosomes, Human, Pair 6; Cytarabine; Daunorubicin; Humans; Karyotyping; Leukemia, Promyelocytic, Acute; Male; Polymerase Chain Reaction; Recurrence; Translocation, Genetic; Tretinoin | 1995 |
Continued complete remission after a PML/RAR-alpha+ autograft in acute promyelocytic leukaemia.
Topics: Antineoplastic Combined Chemotherapy Protocols; Biomarkers, Tumor; Child; Cytarabine; Doxorubicin; Female; Graft Survival; Hematopoiesis; Hematopoietic Stem Cell Transplantation; Humans; Leukemia, Promyelocytic, Acute; Neoplasm Proteins; Neoplasm Transplantation; Neoplastic Stem Cells; Oncogene Proteins, Fusion; Remission Induction; Transplantation, Autologous; Tretinoin | 1996 |
All-trans retinoic acid and short-time, high-dose cytarabine in two children with acute promyelocytic leukemia.
Topics: Adolescent; Antimetabolites, Antineoplastic; Antineoplastic Agents; Child, Preschool; Critical Illness; Cytarabine; Female; Humans; Leukemia, Promyelocytic, Acute; Leukocytosis; Remission Induction; Syndrome; Tretinoin | 1996 |
All-trans-retinoic acid (ATRA) responsive skin relapses of acute promyelocytic leukaemia followed by ATRA-induced pseudotumour cerebri.
Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; Base Sequence; Blotting, Southern; Cytarabine; Female; Humans; Idarubicin; Leukemia, Promyelocytic, Acute; Molecular Sequence Data; Polymerase Chain Reaction; Pseudotumor Cerebri; Skin Neoplasms; Tretinoin | 1996 |
Post-transcriptional regulation of bcl-2 in acute myeloblastic leukemia: significance for response to chemotherapy.
Topics: Anti-Inflammatory Agents; Antibiotics, Antineoplastic; Antimetabolites, Antineoplastic; Blotting, Northern; Blotting, Western; Cytarabine; Daunorubicin; Down-Regulation; Gene Expression Regulation, Leukemic; Granulocyte Colony-Stimulating Factor; Granulocyte-Macrophage Colony-Stimulating Factor; Humans; Hydrocortisone; Leukemia, Myeloid, Acute; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-bcl-2; Remission Induction; RNA, Messenger; Transcription, Genetic; Transcriptional Activation; Tretinoin; Tumor Cells, Cultured | 1996 |
Establishment and characterization of a novel acute promyelocytic leukemia cell line (UF-1) with retinoic acid-resistant features.
Topics: Adult; Antineoplastic Agents; Cell Differentiation; Cell Division; Chromosome Aberrations; Cytarabine; Daunorubicin; DNA Mutational Analysis; Drug Resistance, Neoplasm; Fatal Outcome; Female; HL-60 Cells; Humans; Immunophenotyping; Karyotyping; Leukemia, Promyelocytic, Acute; Mercaptopurine; Neoplasm Proteins; Oncogene Proteins, Fusion; Polymerase Chain Reaction; Prednisolone; Tretinoin; Tumor Cells, Cultured | 1996 |
Differentiation induction therapy with all-trans retinoic acid (ATRA) in a patient with secondary 11q23 leukemia.
Topics: Antineoplastic Combined Chemotherapy Protocols; Child; Chromosome Aberrations; Chromosome Disorders; Chromosomes, Human, Pair 11; Cytarabine; Drug Resistance, Multiple; Etoposide; Humans; Leukemia, Promyelocytic, Acute; Male; Translocation, Genetic; Tretinoin | 1996 |
A role for paclitaxel in the combination chemotherapy of acute myeloblastic leukaemia: preclinical cell culture studies.
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Cell Division; Cytarabine; Dose-Response Relationship, Drug; Drug Synergism; Female; Granulocyte Colony-Stimulating Factor; Granulocyte-Macrophage Colony-Stimulating Factor; Hematopoietic Stem Cells; Humans; Leukemia, Myeloid, Acute; Male; Middle Aged; Paclitaxel; Tretinoin; Tumor Cells, Cultured | 1996 |
Retinoic acid induced neural differentiation in a neuroectodermal cell line immortalized by p53 deficiency.
Topics: Animals; Antimetabolites, Antineoplastic; Autoradiography; Brain; Cell Differentiation; Cell Line; Chromosomes; Cytarabine; Growth Substances; Immunohistochemistry; Mice; Nerve Tissue Proteins; Neurons; Rats; Stem Cells; Thymidine; Tretinoin; Tumor Suppressor Protein p53 | 1997 |
Relapse in the external auditory canal of acute promyelocytic leukemia after treatment with all-trans retinoic acid.
Topics: Agranulocytosis; Antineoplastic Combined Chemotherapy Protocols; Biomarkers, Tumor; Combined Modality Therapy; Cytarabine; Daunorubicin; Ear Canal; Female; Granulocyte Colony-Stimulating Factor; Humans; Idarubicin; Leukemia, Promyelocytic, Acute; Mercaptopurine; Middle Aged; Mitoxantrone; Neoplasm Proteins; Oncogene Proteins, Fusion; Radiotherapy; Recurrence; Remission Induction; Salvage Therapy; Tretinoin; Vindesine | 1997 |
Autologous bone marrow transplantation for acute promyelocytic leukemia in second remission: prognostic relevance of pretransplant minimal residual disease assessment by reverse-transcription polymerase chain reaction of the PML/RAR alpha fusion gene.
Topics: Adolescent; Adult; Antibiotics, Antineoplastic; Antineoplastic Combined Chemotherapy Protocols; Biomarkers, Tumor; Bone Marrow Transplantation; Child; Combined Modality Therapy; Cytarabine; Disease-Free Survival; Female; Follow-Up Studies; Humans; Idarubicin; Leukemia, Promyelocytic, Acute; Male; Middle Aged; Mitoxantrone; Neoplasm Proteins; Neoplasm, Residual; Oncogene Proteins, Fusion; Polymerase Chain Reaction; Prognosis; Prospective Studies; Remission Induction; Salvage Therapy; Transplantation, Autologous; Treatment Outcome; Tretinoin | 1997 |
[Successful treatment of subdural hematoma with operation in a patient with acute promyelocytic leukemia].
Topics: Antineoplastic Combined Chemotherapy Protocols; Cytarabine; Daunorubicin; Disseminated Intravascular Coagulation; Hematoma, Subdural; Humans; Leukemia, Promyelocytic, Acute; Male; Middle Aged; Tretinoin | 1997 |
Differential induction of HNF-3 transcription factors during neuronal differentiation.
Topics: Animals; Astrocytes; Cell Differentiation; Cytarabine; DNA-Binding Proteins; Hepatocyte Nuclear Factor 3-alpha; Hepatocyte Nuclear Factor 3-beta; Mice; Neoplastic Stem Cells; Neurons; Nuclear Proteins; RNA, Antisense; RNA, Messenger; Transcription Factors; Transcriptional Activation; Tretinoin | 1997 |
Induction of differentiation of human myeloid leukemia cells by 2'-deoxycoformycin in combination with 2'-deoxyadenosine.
Topics: Antibiotics, Antineoplastic; Cell Differentiation; Cytarabine; Deoxyadenosines; Drug Combinations; Growth Inhibitors; HL-60 Cells; Humans; Leukemia, Erythroblastic, Acute; Leukemia, Myeloid; Pentostatin; Tretinoin; Tumor Cells, Cultured | 1997 |
Neplanocin A, a potent inhibitor of S-adenosylhomocysteine hydrolase, potentiates granulocytic differentiation of acute promyelocytic leukemia cells induced by all-trans retinoic acid.
Topics: Adenosine; Adenosylhomocysteinase; Antibiotics, Antineoplastic; Antineoplastic Agents; Cell Cycle; Cell Differentiation; Cytarabine; Daunorubicin; DNA, Neoplasm; Drug Synergism; Enzyme Inhibitors; Granulocytes; Humans; Hydrolases; Leukemia, Promyelocytic, Acute; Leukopoiesis; Tretinoin; Tumor Cells, Cultured | 1997 |
Analysis of prognostic factors in newly diagnosed acute promyelocytic leukemia treated with all-trans retinoic acid and chemotherapy. Japan Adult Leukemia Study Group.
Topics: Adolescent; Adult; Age Factors; Aged; Aged, 80 and over; Analysis of Variance; Antineoplastic Combined Chemotherapy Protocols; Bone Marrow Transplantation; Cytarabine; Daunorubicin; Female; Humans; Leukemia, Promyelocytic, Acute; Leukocyte Count; Male; Middle Aged; Prognosis; Prospective Studies; Treatment Outcome; Tretinoin | 1998 |
Retinoic acid syndrome during the treatment of acute myelomonocytic leukaemia with all-trans-retinoic acid and low-dose cytosine arabinoside.
Topics: Cytarabine; Humans; Leukemia, Myelomonocytic, Acute; Leukocyte Count; Leukocytosis; Male; Middle Aged; Syndrome; Tretinoin | 1998 |
Mutant RAS selectively promotes sensitivity of myeloid leukemia cells to apoptosis by a protein kinase C-dependent process.
Topics: 3T3 Cells; Animals; Antineoplastic Agents; Apoptosis; Cell Differentiation; Cytarabine; DNA Primers; Dose-Response Relationship, Drug; Doxorubicin; Humans; Leukemia, Myeloid; Mice; Mutation; Protein Kinase C; Proto-Oncogene Proteins c-bcl-2; Proto-Oncogene Proteins c-raf; Proto-Oncogene Proteins p21(ras); Transfection; Tretinoin; Tumor Cells, Cultured | 1998 |
Influence of increased body mass index on drug toxicity in patients with acute promyelocytic leukemia.
Topics: Adult; Aged; Amsacrine; Antibiotics, Antineoplastic; Antineoplastic Combined Chemotherapy Protocols; Body Mass Index; Cytarabine; Daunorubicin; Female; Heart; Heart Failure; Humans; Leukemia, Promyelocytic, Acute; Male; Mercaptopurine; Obesity; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Remission Induction; Tretinoin | 1998 |
[Prognostic significance of CD7 expression in adult acute myeloid leukemia].
Topics: Adolescent; Adult; Aged; Antigens, CD7; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Biomarkers, Tumor; Child, Preschool; Cytarabine; Daunorubicin; Female; Humans; Leukemia, Myeloid, Acute; Middle Aged; Prednisolone; Prognosis; Survival Rate; Thioguanine; Tretinoin | 1998 |
[Clinical significance of detection of PML-RAR alpha fusion gene of APL during differentiation therapy with ATRA].
Topics: Adolescent; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Child; Cloning, Molecular; Cytarabine; Female; Follow-Up Studies; Harringtonines; Humans; Leukemia, Promyelocytic, Acute; Male; Mercaptopurine; Middle Aged; Oncogene Proteins, Fusion; Tretinoin | 1997 |
Extramedullary involvement in patients with acute promyelocytic leukemia: a report of seven cases.
Topics: Adolescent; Adult; Antibiotics, Antineoplastic; Antimetabolites, Antineoplastic; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Bone Marrow; Brain Neoplasms; Cytarabine; Daunorubicin; Disease Progression; Fatal Outcome; Female; Gene Amplification; Gene Rearrangement; Humans; Idarubicin; Immunophenotyping; Leukemia, Promyelocytic, Acute; Lymph Nodes; Male; Middle Aged; Neoplasm Recurrence, Local; Polymerase Chain Reaction; Receptors, Retinoic Acid; Retinoic Acid Receptor alpha; Skin Neoplasms; Translocation, Genetic; Tretinoin | 1998 |
Management of acute promyelocytic leukemia relapse in the ATRA era.
Topics: Adolescent; Adult; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Bone Marrow Transplantation; Combined Modality Therapy; Cytarabine; Daunorubicin; Etoposide; Female; Humans; Idarubicin; Leukemia, Promyelocytic, Acute; Male; Middle Aged; Mitoxantrone; Recurrence; Remission Induction; Salvage Therapy; Thioguanine; Treatment Outcome; Tretinoin | 1998 |
Human leukemic K562 cells treated with cytosine arabinoside: enhancement of erythroid differentiation by retinoic acid and retinol.
Topics: Antimetabolites, Antineoplastic; Cell Differentiation; Cytarabine; Drug Synergism; Erythropoiesis; Humans; K562 Cells; Keratolytic Agents; Leukemia; Tretinoin; Vitamin A | 1998 |
Complement receptor type 1 gene regulation: retinoic acid and cytosine arabinoside increase CR1 expression.
Topics: Cytarabine; Dose-Response Relationship, Immunologic; Gene Expression Regulation; Granulocyte-Macrophage Colony-Stimulating Factor; HL-60 Cells; Humans; Interferon-gamma; Interleukin-1; Interleukin-6; K562 Cells; Kinetics; Monocytes; Neutrophils; Receptors, Complement 3b; RNA, Messenger; Tretinoin; Tumor Necrosis Factor-alpha; U937 Cells | 1999 |
Differential expression and phosphorylation of CTCF, a c-myc transcriptional regulator, during differentiation of human myeloid cells.
Topics: Blotting, Northern; Blotting, Western; Burkitt Lymphoma; CCCTC-Binding Factor; Cell Differentiation; Cytarabine; Dimethyl Sulfoxide; DNA-Binding Proteins; Down-Regulation; Erythrocytes; Gene Expression Regulation; Humans; Isoelectric Focusing; Leukemia, Myeloid; Leukocytes; Megakaryocytes; Phosphorylation; Proto-Oncogene Proteins c-myc; Repressor Proteins; RNA Processing, Post-Transcriptional; Staurosporine; Tetradecanoylphorbol Acetate; Transcription Factors; Tretinoin; Tumor Cells, Cultured | 1999 |
Cryptic insertion (15;17) in a case of acute promyelocytic leukemia detected by fluorescence in situ hybridization.
Topics: Adult; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Biomarkers, Tumor; Chromosomes, Human, Pair 15; Chromosomes, Human, Pair 17; Cytarabine; Etoposide; Fatal Outcome; Hematopoietic Stem Cell Transplantation; Humans; In Situ Hybridization, Fluorescence; Leukemia, Promyelocytic, Acute; Male; Mitoxantrone; Neoplasm Proteins; Oncogene Proteins, Fusion; Reverse Transcriptase Polymerase Chain Reaction; Translocation, Genetic; Tretinoin | 1999 |
Pilot study of combined therapy with interferon-alpha, arabinosyl cytosine and all-trans retinoic acid in patients with chronic myeloid leukemia in the chronic phase.
Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; Cytarabine; Female; Humans; Interferon-alpha; Leukemia, Myelogenous, Chronic, BCR-ABL Positive; Male; Middle Aged; Pilot Projects; Tretinoin | 1999 |
Long-term molecular remission in promyelocytic transformation of myeloproliferative disease.
Topics: Antineoplastic Combined Chemotherapy Protocols; Biomarkers, Tumor; Chromosomes, Human, Pair 15; Chromosomes, Human, Pair 17; Cytarabine; Daunorubicin; Disease Progression; Etoposide; Female; Humans; Idarubicin; Karyotyping; Leukemia, Promyelocytic, Acute; Male; Middle Aged; Neoplasm Proteins; Oncogene Proteins, Fusion; Polycythemia Vera; Preleukemia; Prognosis; Remission Induction; Thrombocythemia, Essential; Thrombophilia; Translocation, Genetic; Tretinoin | 1999 |
All-trans-retinoic acid increases cytosine arabinoside cytotoxicity in HL-60 human leukemia cells in spite of decreased cellular ara-CTP accumulation.
Topics: Analysis of Variance; Antimetabolites, Antineoplastic; Antineoplastic Combined Chemotherapy Protocols; Apoptosis; Arabinofuranosylcytosine Triphosphate; Cytarabine; DNA Fragmentation; Drug Resistance, Neoplasm; Electrophoresis, Agar Gel; Flow Cytometry; HL-60 Cells; Humans; Tretinoin; Tumor Cells, Cultured | 1999 |
Effect of all-trans retinoic acid on chemotherapy induced apoptosis and down-regulation of Bcl-2 in human myeloid leukaemia CD34 positive cells.
Topics: Antigens, CD34; Antimetabolites, Antineoplastic; Apoptosis; Cytarabine; Humans; Leukemia, Myeloid; Proto-Oncogene Proteins c-bcl-2; Tretinoin; Tumor Cells, Cultured; Vidarabine | 1999 |
In vitro effect on human leukemic K562 cells of co-administration of liposome-associated retinoids and cytosine arabinoside (Ara-C).
Topics: Cell Differentiation; Cell Division; Cytarabine; Drug Synergism; Freeze Fracturing; Hemoglobins; Humans; K562 Cells; Liposomes; Tretinoin; Vitamin A | 1999 |
The lung resistance protein (LRP) predicts poor outcome in acute myeloid leukemia.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Antibodies, Monoclonal; Antineoplastic Combined Chemotherapy Protocols; Cytarabine; Daunorubicin; Disease-Free Survival; Drug Resistance, Multiple; Etoposide; Female; Humans; Idarubicin; Immunohistochemistry; Karyotyping; Leukemia, Myeloid, Acute; Male; Middle Aged; Neoplasm Proteins; Predictive Value of Tests; Prognosis; Survival Rate; Tretinoin; Vault Ribonucleoprotein Particles | 1999 |
Expression of Bcl-2-related genes in normal and AML progenitors: changes induced by chemotherapy and retinoic acid.
Topics: Acute Disease; Antigens, CD34; Antineoplastic Agents; Apoptosis; bcl-2-Associated X Protein; bcl-Associated Death Protein; bcl-X Protein; Carrier Proteins; Cytarabine; Down-Regulation; Flow Cytometry; Gene Expression; Genes, bcl-2; Hematopoietic Stem Cells; Humans; Leukemia, Myeloid; Neoplasm, Residual; Phosphorylation; Phosphoserine; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-bcl-2; RNA, Messenger; Survival Rate; Tretinoin; Tumor Cells, Cultured | 1999 |
Induction of erythroid differentiation of human K562 cells by 3-O-acyl-1,2-O-isopropylidene-D-glucofuranose derivatives.
Topics: Cell Differentiation; Cytarabine; Gene Expression Regulation; Glucose; Hematopoiesis; Hemoglobins; Hexoses; Humans; K562 Cells; Plicamycin; Tretinoin | 1999 |
Two new 3' PML breakpoints in t(15;17)(q22;q21)-positive acute promyelocytic leukemia.
Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; Base Sequence; Chromosomes, Human, Pair 15; Chromosomes, Human, Pair 17; Cytarabine; Exons; Fatal Outcome; Humans; Idarubicin; Leukemia, Promyelocytic, Acute; Male; Molecular Sequence Data; Reverse Transcriptase Polymerase Chain Reaction; Translocation, Genetic; Tretinoin | 2000 |
[Central nervous system relapse with multiple brain masses in an acute promyelocytic leukemia patient treated with all-trans retinoic acid].
Topics: Administration, Oral; Adult; Antineoplastic Combined Chemotherapy Protocols; Brain Neoplasms; Central Nervous System Neoplasms; Cytarabine; Daunorubicin; Female; Humans; Injections, Spinal; Leukemia, Promyelocytic, Acute; Neoplasm Recurrence, Local; Remission Induction; Treatment Outcome; Tretinoin | 1999 |
Induction of gp130 and LIF by differentiation inducers in human myeloid leukemia K562 cells.
Topics: Antigens, CD; Antigens, Differentiation, B-Lymphocyte; Biomarkers; Butyrates; Cell Differentiation; Cytarabine; Cytokine Receptor gp130; Drug Synergism; Enzyme Induction; Erythropoiesis; Glycophorins; Growth Inhibitors; Hemin; Humans; Interleukin-6; K562 Cells; Leukemia Inhibitory Factor; Lymphokines; Membrane Glycoproteins; Naphthol AS D Esterase; Receptors, Transferrin; Tetradecanoylphorbol Acetate; Tretinoin | 1999 |
Acute promyelocytic leukemia with del(6)(p23).
Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Chromosome Deletion; Chromosomes, Human, Pair 15; Chromosomes, Human, Pair 17; Chromosomes, Human, Pair 6; Cytarabine; Humans; Idarubicin; Karyotyping; Leukemia, Promyelocytic, Acute; Male; Neoplasm Proteins; Oncogene Proteins, Fusion; Remission Induction; Reverse Transcriptase Polymerase Chain Reaction; Tretinoin | 2000 |
Regulation of drug sensitivity by ribosomal protein S3a.
Topics: Animals; Antibiotics, Antineoplastic; Antimetabolites, Antineoplastic; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Apoptosis; Cell Line; Cryopreservation; Cytarabine; DNA Replication; DNA, Neoplasm; Doxorubicin; Drug Resistance, Neoplasm; Gene Targeting; Humans; Leukemia, Myeloid, Acute; Leukemia, Myelomonocytic, Chronic; Neoplasm Proteins; Neoplastic Stem Cells; Paclitaxel; Phosphorylation; Phosphoserine; Protein Processing, Post-Translational; Rats; Ribosomal Proteins; Tissue Preservation; Treatment Outcome; Tretinoin | 2000 |
Prolonged third remission in a patient with acute promyelocytic leukemia after consolidation chemotherapy with intermittent intermediate dose ara-C and maintenance with intermittent all-trans retinoic acid (ATRA).
Topics: Antineoplastic Combined Chemotherapy Protocols; Cytarabine; Female; Humans; Leukemia, Promyelocytic, Acute; Middle Aged; Remission Induction; Time Factors; Tretinoin | 2000 |
[Retrospective study of acute myelogenous leukemia in elderly patients: treatment and outcome of 83 consecutive patients].
Topics: Age Factors; Aged; Aged, 80 and over; Chromosomes, Human, Pair 5; Chromosomes, Human, Pair 7; Cytarabine; Daunorubicin; Drug Therapy, Combination; Gene Deletion; Humans; Leukemia, Myeloid, Acute; Middle Aged; Mitoxantrone; Remission Induction; Retrospective Studies; Treatment Outcome; Tretinoin | 2000 |
Treatment of relapsing acute promyelocytic leukemia by all-trans retinoic acid therapy followed by timed sequential chemotherapy and stem cell transplantation. APL Study Group. Acute promyelocytic leukemia.
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Combined Modality Therapy; Cytarabine; Drug Administration Schedule; Etoposide; Female; Hematopoietic Stem Cell Transplantation; Humans; Leukemia, Promyelocytic, Acute; Male; Middle Aged; Mitoxantrone; Recurrence; Tretinoin | 2000 |
Interferon may reduce minimal residual disease of acute promyelocytic leukemia.
Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; Cytarabine; Daunorubicin; Female; Humans; Idarubicin; Interferons; Leukemia, Promyelocytic, Acute; Neoplasm, Residual; Recurrence; Remission Induction; Tretinoin | 2000 |
Respiratory failure during induction chemotherapy for acute myelomonocytic leukaemia (FAB M4Eo) with ara-C and all-trans retinoic acid.
Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; Cytarabine; Daunorubicin; Dexamethasone; Female; Glucocorticoids; Humans; Leukemia, Myelomonocytic, Acute; Remission Induction; Respiratory Insufficiency; Thioguanine; Tretinoin | 2000 |
Combination of interferon alpha with either Ara-C or ATRA in vitro reduces the selective action of interferon against CML CFU-GM.
Topics: Cell Division; Cytarabine; Hematopoietic Stem Cells; Humans; In Situ Hybridization, Fluorescence; Interferon-alpha; Leukemia, Myelogenous, Chronic, BCR-ABL Positive; Tretinoin | 2000 |
Diffuse alveolar hemorrhage in acute promyelocytic leukemia patients treated with ATRA--a manifestation of the basic disease or the treatment.
Topics: Adult; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Blood Coagulation Tests; Cytarabine; Daunorubicin; Dyspnea; Fatal Outcome; Fever; Hemorrhage; Humans; Leukemia, Promyelocytic, Acute; Lung Diseases; Male; Middle Aged; Pulmonary Alveoli; Remission Induction; Syndrome; Tretinoin | 2000 |
Avascular necrosis of head of femur in a patient with acute promyelocytic leukemia.
Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; Cytarabine; Daunorubicin; Dexamethasone; Femur Head Necrosis; Humans; Leukemia, Promyelocytic, Acute; Male; Tretinoin | 2000 |
Allogeneic bone marrow transplantation improves the outcome of de novo AML with trilineage dysplasia (AML-TLD).
Topics: Adolescent; Adult; Age Factors; Aged; Antineoplastic Combined Chemotherapy Protocols; Bone Marrow Transplantation; Cell Lineage; Combined Modality Therapy; Cytarabine; Daunorubicin; Disease-Free Survival; Female; Humans; Japan; Leukemia, Myeloid; Life Tables; Male; Middle Aged; Neoplastic Stem Cells; Remission Induction; Retrospective Studies; Survival Analysis; Transplantation Conditioning; Transplantation, Homologous; Treatment Outcome; Tretinoin | 2000 |
De novo acute myeloid leukemia in the elderly; a consistent fraction of long-term survivors by standard-dose chemotherapy.
Topics: Acute Disease; Aged; Aged, 80 and over; Aging; Antineoplastic Combined Chemotherapy Protocols; Cytarabine; Daunorubicin; Female; Humans; Karyotyping; Leukemia, Myeloid; Male; Mercaptopurine; Middle Aged; Prognosis; Treatment Outcome; Tretinoin | 2001 |
In vitro apoptotic response of freshly isolated chronic myeloid leukemia cells to all-trans retinoic acid and cytosine arabinoside.
Topics: Antigens, CD; Antigens, Differentiation, Myelomonocytic; Antimetabolites, Antineoplastic; Antineoplastic Combined Chemotherapy Protocols; Apoptosis; Biomarkers, Tumor; Cell Differentiation; Cell Separation; Cytarabine; DNA Fragmentation; Electrophoresis, Agar Gel; Female; Granulocytes; Humans; Immunophenotyping; Leukemia, Myelogenous, Chronic, BCR-ABL Positive; Leukemia, Myeloid, Chronic-Phase; Macrophage-1 Antigen; Male; Middle Aged; Sialic Acid Binding Ig-like Lectin 3; Tretinoin; Tumor Cells, Cultured | 2000 |
Induction of differentiation of acute promyelocytic leukemia cells by a cytidine deaminase-resistant analogue of 1-beta-D-arabinofuranosylcytosine, 1-(2-deoxy-2-methylene-beta-D-erythro-pentofuranosyl)cytidine.
Topics: Antimetabolites, Antineoplastic; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Cell Differentiation; Cell Division; Cytarabine; Cytidine Deaminase; Deoxycytidine; Drug Resistance, Neoplasm; Drug Synergism; Female; Growth Inhibitors; HL-60 Cells; Humans; Leukemia, Promyelocytic, Acute; Male; Middle Aged; Tretinoin; Tumor Cells, Cultured; U937 Cells | 2001 |
[All-trans retinoic acid combined with low-dose cytosine arabinoside treatment for acute myelogenous leukemia with trilineage myelodysplasia--a case report].
Topics: Antimetabolites, Antineoplastic; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Cytarabine; Female; Humans; Leukemia, Myeloid, Acute; Middle Aged; Neural Tube Defects; Tretinoin | 2001 |
Acute promyelocytic leukemia with additional chromosome abnormalities in a renal transplant case.
Topics: Antineoplastic Combined Chemotherapy Protocols; Chromosome Aberrations; Chromosomes, Human, Pair 1; Chromosomes, Human, Pair 13; Chromosomes, Human, Pair 14; Chromosomes, Human, Pair 15; Chromosomes, Human, Pair 17; Chromosomes, Human, Pair 22; Cytarabine; Humans; Idarubicin; Immunosuppressive Agents; In Situ Hybridization, Fluorescence; Kidney Transplantation; Leukemia, Promyelocytic, Acute; Male; Middle Aged; Mitoxantrone; Polycystic Kidney Diseases; Recurrence; Remission Induction; Reverse Transcriptase Polymerase Chain Reaction; Tretinoin | 2001 |
Acute arterial occlusion as the presenting feature in acute promyelocytic leukaemia.
Topics: Amputation, Surgical; Anticoagulants; Antineoplastic Combined Chemotherapy Protocols; Arterial Occlusive Diseases; Cytarabine; Daunorubicin; Female; Foot Diseases; Heparin; Humans; Leukemia, Promyelocytic, Acute; Middle Aged; Necrosis; Popliteal Artery; Thioguanine; Tretinoin | 2001 |
Novel triterpenoid CDDO-Me is a potent inducer of apoptosis and differentiation in acute myelogenous leukemia.
Topics: Annexin A5; Apoptosis; bcl-2-Associated X Protein; Blast Crisis; Caspase 3; Caspases; Cell Differentiation; Cell Survival; Cytarabine; DNA Fragmentation; Drug Interactions; Flow Cytometry; HL-60 Cells; Humans; Leukemia, Myeloid, Acute; Membrane Potentials; Mitogen-Activated Protein Kinases; Oleanolic Acid; Phosphorylation; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-bcl-2; Retinoids; Tretinoin; Tumor Cells, Cultured | 2002 |
Effects of combinations of therapeutic agents on the proliferation of progenitor cells in chronic myeloid leukaemia.
Topics: Alkyl and Aryl Transferases; Antineoplastic Combined Chemotherapy Protocols; Area Under Curve; Benzamides; Cell Division; Cytarabine; Enzyme Inhibitors; Farnesyltranstransferase; Humans; Imatinib Mesylate; Interferon-alpha; Leukemia, Myelogenous, Chronic, BCR-ABL Positive; Piperazines; Protein-Tyrosine Kinases; Pyrimidines; Stem Cells; Tretinoin; Tyrphostins | 2002 |
Secondary acute promyelocytic leukemia in a patient with non-Hodgkin's lymphoma treated with VP-16 and MST-16.
Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Biomarkers, Tumor; Cyclophosphamide; Cytarabine; Doxorubicin; Etoposide; Female; Humans; Idarubicin; Leukemia, Promyelocytic, Acute; Lymphoma, Large B-Cell, Diffuse; Lymphoma, Non-Hodgkin; Neoplasm Proteins; Neoplasms, Second Primary; Oncogene Proteins, Fusion; Piperazines; Prednisolone; Remission Induction; Tretinoin; Vincristine | 2002 |
Benign thymic hyperplasia after chemotherapy for acute myeloid leukemia.
Topics: Antineoplastic Combined Chemotherapy Protocols; Child; Cytarabine; Daunorubicin; Female; Humans; Hyperplasia; Leukemia, Promyelocytic, Acute; Pseudotumor Cerebri; Radiography; Sweet Syndrome; Thymus Gland; Tretinoin | 2001 |
Automated differential counts in acute promyelocytic leukemia patients may be misleading.
Topics: Adolescent; Antineoplastic Combined Chemotherapy Protocols; Blood Cell Count; Cytarabine; Diagnostic Errors; Eosinophils; Female; Humans; Idarubicin; Leukemia, Promyelocytic, Acute; Leukocyte Count; Tretinoin | 2002 |
In vivo use of all-trans retinoic acid prior to induction chemotherapy improves complete remission rate and increases rhodamine 123 uptake in patients with de novo acute myeloid leukemia.
Topics: Acute Disease; Adolescent; Adult; Aged; Antigens, CD; Antimetabolites, Antineoplastic; Antineoplastic Combined Chemotherapy Protocols; Biomarkers, Tumor; Case-Control Studies; Cytarabine; Drug Resistance, Multiple; Etoposide; Female; Fluorescent Dyes; Humans; Idarubicin; Immunophenotyping; Leukemia, Myeloid; Leukocyte Count; Male; Middle Aged; Proto-Oncogene Proteins c-bcl-2; Remission Induction; Rhodamine 123; Treatment Outcome; Tretinoin | 2002 |
The anti-apoptotic genes Bcl-X(L) and Bcl-2 are over-expressed and contribute to chemoresistance of non-proliferating leukaemic CD34+ cells.
Topics: Acute Disease; Adult; Aged; Aged, 80 and over; Antigens, CD34; Antimetabolites, Antineoplastic; Antineoplastic Agents; Apoptosis; bcl-X Protein; beta 2-Microglobulin; Bone Marrow Cells; Cell Division; Cytarabine; Down-Regulation; fas Receptor; Flow Cytometry; Genes, bcl-2; Hematopoietic Stem Cells; Humans; Leukemia, Myeloid; Middle Aged; Proto-Oncogene Proteins c-bcl-2; Tretinoin | 2002 |
Prolonged administration of all-trans retinoic acid in combination with intensive chemotherapy and G-CSF for adult acute myelogenous leukemia: single-centre pilot study in different risk groups.
Topics: Acute Disease; Adolescent; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Apoptosis; Cytarabine; Disease-Free Survival; Etoposide; Female; Filgrastim; Granulocyte Colony-Stimulating Factor; Headache; Humans; Idarubicin; Leukemia, Myeloid; Life Tables; Male; Middle Aged; Neoplastic Stem Cells; Patient Compliance; Pilot Projects; Recombinant Proteins; Remission Induction; Survival Analysis; Treatment Failure; Tretinoin | 2002 |
The catalytic DNA topoisomerase II inhibitor ICRF-193 and all-trans retinoic acid cooperatively induce granulocytic differentiation of acute promyelocytic leukemia cells: candidate drugs for chemo-differentiation therapy against acute promyelocytic leukem
Topics: Antineoplastic Agents; Catalysis; Cell Cycle; Cell Differentiation; Cell Division; Cyclin-Dependent Kinase Inhibitor p21; Cyclins; Cytarabine; Daunorubicin; Deoxycytidine; Diketopiperazines; Drug Screening Assays, Antitumor; Drug Synergism; Enzyme Inhibitors; Granulocytes; HL-60 Cells; Humans; Leukemia, Promyelocytic, Acute; Neoplasm Proteins; Neoplastic Stem Cells; Piperazines; Razoxane; Receptors, Retinoic Acid; Retinoic Acid Receptor alpha; RNA, Messenger; RNA, Neoplasm; Topoisomerase II Inhibitors; Tretinoin; Tumor Cells, Cultured; U937 Cells | 2002 |
Impact of the expression of P glycoprotein, the multidrug resistance-related protein, bcl-2, mutant p53, and heat shock protein 27 on response to induction therapy and long-term survival in patients with de novo acute myeloid leukemia.
Topics: Adolescent; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Apoptosis; ATP Binding Cassette Transporter, Subfamily B, Member 1; Cytarabine; Drug Resistance, Multiple; Drug Resistance, Neoplasm; Female; Follow-Up Studies; Gene Expression; Genes, bcl-2; Genes, MDR; Genes, p53; Heat-Shock Proteins; Humans; Idarubicin; Leukemia, Myeloid; Male; Middle Aged; Neoplasm Proteins; Neoplastic Stem Cells; Prognosis; Proto-Oncogene Proteins c-bcl-2; Remission Induction; Survival Rate; Treatment Outcome; Tretinoin; Tumor Cells, Cultured; Tumor Suppressor Protein p53 | 2002 |
Preliminary study on in vitro induced differentiation of embryonic stem cells into neurons.
Topics: Animals; Cell Differentiation; Cell Division; Cells, Cultured; Coculture Techniques; Cytarabine; Embryo, Mammalian; Glaucoma; Hepatocytes; Humans; Neurons; Rats; Retinal Ganglion Cells; Stem Cell Transplantation; Stem Cells; Tretinoin | 2000 |
All- trans-retinoic acid increases cytotoxicity of 1-beta-D-arabinofuranosylcytosine in NB4 cells.
Topics: Antimetabolites, Antineoplastic; Antineoplastic Agents; Cell Death; Cytarabine; Drug Interactions; Genes, bcl-2; Leukemia, Promyelocytic, Acute; Nucleoside Transport Proteins; Tretinoin; Tumor Cells, Cultured | 2003 |
Multiple complete remissions in a patient with acute myeloid leukemia (M4eo) with low-dose cytosine arabinoside and all-trans retinoic acid.
Topics: Antineoplastic Combined Chemotherapy Protocols; Cytarabine; Cytogenetic Analysis; Female; Humans; Leukemia, Myelomonocytic, Acute; Middle Aged; Recurrence; Remission Induction; Tretinoin | 2003 |
Successful treatment for multiple cerebral hemorrhage in a newly diagnosed patient with acute promyelocytic leukemia.
Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; Cerebral Hemorrhage; Cytarabine; Female; Humans; Idarubicin; Leukemia, Promyelocytic, Acute; Reverse Transcriptase Polymerase Chain Reaction; Tomography, X-Ray Computed; Treatment Outcome; Tretinoin | 2003 |
[Successful treatment of acute promyelocytic leukemia in a pregnant patient with all-trans retinoic acid and chemotherapy resulting in a safe delivery].
Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; Cesarean Section; Cytarabine; Daunorubicin; Female; Humans; Infant, Newborn; Leukemia, Promyelocytic, Acute; Male; Pregnancy; Pregnancy Complications, Hematologic; Pregnancy Outcome; Remission Induction; Tretinoin | 2003 |
Myelodysplastic syndrome after acute promyelocytic leukemia: the European APL group experience.
Topics: Adolescent; Adult; Aged; Antibiotics, Antineoplastic; Antineoplastic Combined Chemotherapy Protocols; Child; Cytarabine; Cytogenetic Analysis; Female; Follow-Up Studies; Humans; Incidence; Leukemia, Promyelocytic, Acute; Male; Middle Aged; Myelodysplastic Syndromes; Remission Induction; Retrospective Studies; Tretinoin | 2003 |
Acute arterial thrombosis in acute promyelocytic leukaemia.
Topics: Amputation, Surgical; Antineoplastic Combined Chemotherapy Protocols; Arterial Occlusive Diseases; Cysteine Endopeptidases; Cytarabine; Daunorubicin; Female; Gangrene; Humans; Intermittent Claudication; Ischemia; Leg; Leukemia, Promyelocytic, Acute; Middle Aged; Neoplasm Proteins; Neoplastic Stem Cells; Popliteal Artery; Remission Induction; Smoking; Thioguanine; Thrombophilia; Thromboplastin; Thrombosis; Toes; Tretinoin | 2003 |
A new selective AKT pharmacological inhibitor reduces resistance to chemotherapeutic drugs, TRAIL, all-trans-retinoic acid, and ionizing radiation of human leukemia cells.
Topics: Antineoplastic Agents; bcl-Associated Death Protein; Blotting, Western; Carrier Proteins; CASP8 and FADD-Like Apoptosis Regulating Protein; Caspases; Chromones; Cytarabine; Cytochrome c Group; Drug Resistance, Neoplasm; Enzyme Inhibitors; Etoposide; HL-60 Cells; Humans; Inhibitor of Apoptosis Proteins; Inositol; Intracellular Signaling Peptides and Proteins; Isoenzymes; Morpholines; Phosphatidylinositol 3-Kinases; Phosphoinositide-3 Kinase Inhibitors; Phosphoric Monoester Hydrolases; Phosphorylation; Protein Kinase C; Protein Kinase C-theta; Protein Serine-Threonine Kinases; Proteins; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-akt; PTEN Phosphohydrolase; Radiation, Ionizing; Ribosomal Protein S6 Kinases, 70-kDa; Transfection; Tretinoin; Tumor Suppressor Proteins; Ubiquitin-Protein Ligases | 2003 |
Pulmonary embolism and thrombotic thrombocytopenic purpura in acute promyelocytic leukemia treated with all-trans retinoic acid.
Topics: Adult; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Cytarabine; Daunorubicin; Humans; Leukemia, Promyelocytic, Acute; Leukocytosis; Male; Pulmonary Embolism; Purpura, Thrombotic Thrombocytopenic; Remission Induction; Tretinoin | 2003 |
Low L-selectin (CD62L) expression in acute myeloid leukemia correlates with a bad cytogenetic risk.
Topics: Acute Disease; Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Bone Marrow Cells; Chromosome Aberrations; Cytarabine; Daunorubicin; Disease-Free Survival; Female; Humans; L-Selectin; Leukemia, Myeloid; Male; Middle Aged; Mitoxantrone; Neoplasm Proteins; Neoplastic Stem Cells; Remission Induction; Risk; Thioguanine; Treatment Outcome; Tretinoin | 2003 |
MLL/AF-1p fusion in therapy-related early pre-B acute lymphoblastic leukemia with t(1;11)(p32;q23) translocation developing in the relapse phase of acute promyelocytic leukemia.
Topics: Antineoplastic Agents, Phytogenic; Antineoplastic Combined Chemotherapy Protocols; Chromosomes, Human, Pair 1; Chromosomes, Human, Pair 11; Cytarabine; Daunorubicin; Enzyme Inhibitors; Etoposide; Fatal Outcome; Humans; Idarubicin; In Situ Hybridization, Fluorescence; Leukemia, Promyelocytic, Acute; Male; Middle Aged; Mitoxantrone; Myeloid-Lymphoid Leukemia Protein; Neoplasm Proteins; Neoplasms, Second Primary; Oncogene Proteins, Fusion; Precursor B-Cell Lymphoblastic Leukemia-Lymphoma; Recurrence; Topoisomerase II Inhibitors; Translocation, Genetic; Tretinoin | 2003 |
Long-lasting RNAi activity in mammalian neurons.
Topics: Animals; Apoptosis; Cell Differentiation; Cell Division; Cell Line, Tumor; Cells, Cultured; Cytarabine; Gene Expression Profiling; Hippocampus; Mice; Mice, Inbred ICR; Neurons; RNA, Double-Stranded; RNA, Small Interfering; Teratocarcinoma; Time Factors; Tretinoin | 2004 |
Tailored therapy of adult acute leukaemia in Jehovah's Witnesses: unjustified reluctance to treat.
Topics: Acute Disease; Adult; Antineoplastic Combined Chemotherapy Protocols; Case Management; Cytarabine; Daunorubicin; Etoposide; Female; Hemoglobins; Hemorrhage; Humans; Jehovah's Witnesses; Leukemia; Male; Middle Aged; Multiple Organ Failure; Patient Acceptance of Health Care; Refusal to Treat; Remission Induction; Tretinoin; Vincristine | 2004 |
Increased expression of N-acetylglucosaminyltransferase-V in human hepatoma cells by retinoic acid and 1alpha,25-dihydroxyvitamin D3.
Topics: Albumins; Calcitriol; Carcinoma, Hepatocellular; Cytarabine; Dimethyl Sulfoxide; Enzyme Activation; Humans; Liver Neoplasms; N-Acetylglucosaminyltransferases; Pyridines; Tretinoin | 2004 |
A single-center, retrospective study of management and outcome of 45 elderly AML patients, diagnosed in 2001.
Topics: Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Cytarabine; Etoposide; Female; Granulocyte Colony-Stimulating Factor; Humans; Idarubicin; Leukemia, Myeloid, Acute; Male; Middle Aged; Myelodysplastic Syndromes; Recurrence; Remission Induction; Retrospective Studies; Time Factors; Treatment Outcome; Tretinoin | 2004 |
Acute pancreatitis during all-trans-retinoic acid treatment for acute promyelocytic leukemia in a patient without overt hypertriglyceridemia.
Topics: Acute Disease; Antineoplastic Combined Chemotherapy Protocols; Cytarabine; Humans; Hypertriglyceridemia; Idarubicin; Leukemia, Promyelocytic, Acute; Male; Middle Aged; Pancreatitis; Tretinoin | 2005 |
TRAIL decoy receptors mediate resistance of acute myeloid leukemia cells to TRAIL.
Topics: Acute Disease; Adolescent; Adult; Antineoplastic Agents; Apoptosis; Caspase 3; Caspase 8; Cell Differentiation; Cell Membrane; Cytarabine; Drug Resistance, Neoplasm; Etoposide; Female; GPI-Linked Proteins; Granulocytes; HL-60 Cells; Humans; Hydroxyurea; Leukemia, Myeloid; Leukemia, Promyelocytic, Acute; Male; Middle Aged; Monocytes; Oncogene Proteins, Fusion; Receptors, TNF-Related Apoptosis-Inducing Ligand; Receptors, Tumor Necrosis Factor; Receptors, Tumor Necrosis Factor, Member 10c; Recombinant Fusion Proteins; Tretinoin; Tumor Cells, Cultured; Tumor Necrosis Factor Decoy Receptors; Tumor Stem Cell Assay; U937 Cells | 2005 |
Limited value of FLT3 mRNA expression in the bone marrow for prognosis and monitoring of patients with acute myeloid leukemia.
Topics: Acute Disease; Antineoplastic Combined Chemotherapy Protocols; Biomarkers, Tumor; Bone Marrow; Combined Modality Therapy; Cytarabine; Daunorubicin; Etoposide; Female; fms-Like Tyrosine Kinase 3; Hematopoietic Stem Cell Transplantation; Humans; Leukemia, Myeloid; Male; Middle Aged; Neoplasm Proteins; Neoplasm, Residual; Prognosis; Remission Induction; RNA, Messenger; RNA, Neoplasm; Survival Analysis; Tretinoin | 2005 |
Acute promyelocytic leukemia after living donor partial orthotopic liver transplantation in two Japanese girls.
Topics: Antineoplastic Combined Chemotherapy Protocols; Biliary Atresia; Child; Child, Preschool; Cytarabine; Daunorubicin; Female; Graft vs Host Disease; Humans; Immunosuppressive Agents; Leukemia, Promyelocytic, Acute; Liver Transplantation; Living Donors; Ornithine Carbamoyltransferase Deficiency Disease; Remission Induction; Tacrolimus; Tretinoin | 2005 |
Oncogenic potential of the transcription factor LYL1 in acute myeloblastic leukemia.
Topics: Antineoplastic Agents; Antineoplastic Agents, Alkylating; Basic Helix-Loop-Helix Transcription Factors; Bone Marrow; Cell Transformation, Neoplastic; Cytarabine; DNA-Binding Proteins; DNA, Complementary; Drug Resistance, Neoplasm; Electroporation; Gene Expression Profiling; Humans; Leukemia, Myeloid, Acute; Myelodysplastic Syndromes; Neoplasm Proteins; Phenotype; Retroviridae; Reverse Transcriptase Polymerase Chain Reaction; Tretinoin; Tumor Cells, Cultured | 2005 |
[JWA gene in regulating committed differentiation of HL-60 cells induced by ATRA, Ara-C and TPA].
Topics: Antineoplastic Agents; Blotting, Western; Cell Differentiation; Cytarabine; Heat-Shock Proteins; HL-60 Cells; HSP27 Heat-Shock Proteins; HSP70 Heat-Shock Proteins; Humans; Intracellular Signaling Peptides and Proteins; Membrane Transport Proteins; Molecular Chaperones; Neoplasm Proteins; Proto-Oncogene Proteins c-bcl-2; Reverse Transcriptase Polymerase Chain Reaction; Tetradecanoylphorbol Acetate; Time Factors; Tretinoin | 2005 |
The prognostic value of MLL-AF9 detection in patients with t(9;11)(p22;q23)-positive acute myeloid leukemia.
Topics: Adolescent; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Biomarkers, Tumor; Chromosomes, Human, Pair 11; Chromosomes, Human, Pair 9; Cohort Studies; Combined Modality Therapy; Cytarabine; Etoposide; Humans; Idarubicin; Leukemia, Myeloid; Middle Aged; Mitoxantrone; Multicenter Studies as Topic; Myeloid-Lymphoid Leukemia Protein; Neoplasm, Residual; Oncogene Proteins, Fusion; Peripheral Blood Stem Cell Transplantation; Polymerase Chain Reaction; Prognosis; Randomized Controlled Trials as Topic; Recurrence; Remission Induction; Survival Analysis; Translocation, Genetic; Treatment Outcome; Tretinoin | 2005 |
JWA, a novel signaling molecule, involved in the induction of differentiation of human myeloid leukemia cells.
Topics: Blotting, Western; Bone Marrow Cells; Cell Cycle; Cell Differentiation; Cell Line, Tumor; Cells, Cultured; Cytarabine; Gene Silencing; Granulocytes; Heat-Shock Proteins; Hemin; HL-60 Cells; Humans; Intracellular Signaling Peptides and Proteins; K562 Cells; Leukemia, Myeloid; Macrophages; Membrane Transport Proteins; Monocytes; Reverse Transcriptase Polymerase Chain Reaction; RNA Interference; Tetradecanoylphorbol Acetate; Time Factors; Tretinoin; U937 Cells | 2006 |
[Adams-Stokes attack due to complete atrioventricular block in a patient with acute promyelocytic leukemia during remission induction therapy using all-trans retinoic acid].
Topics: Antineoplastic Combined Chemotherapy Protocols; Cytarabine; Drug Administration Schedule; Heart Block; Humans; Leukemia, Promyelocytic, Acute; Male; Middle Aged; Mitoxantrone; Pacemaker, Artificial; Remission Induction; Tretinoin | 2005 |
Arsenic trioxide-responsive leukemia cutis in a patient with acute promyelocytic leukemia after ATRA treatment.
Topics: Adolescent; Anthracyclines; Antimetabolites, Antineoplastic; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Arsenic Trioxide; Arsenicals; Cytarabine; Female; Humans; Leukemia; Leukemia, Promyelocytic, Acute; Oxides; Risk; Skin; Tretinoin | 2006 |
Sivelestat relieves respiratory distress refractory to dexamethasone in all-trans retinoic acid syndrome: a report of two cases.
Topics: Anthracyclines; Antineoplastic Combined Chemotherapy Protocols; Cytarabine; Cytoprotection; Dexamethasone; Female; Glycine; Humans; Intracranial Hemorrhages; Leukemia, Promyelocytic, Acute; Male; Prospective Studies; Radiography; Randomized Controlled Trials as Topic; Remission Induction; Respiratory Distress Syndrome; Serine Proteinase Inhibitors; Sulfonamides; Tretinoin | 2006 |
Late relapses in acute promyelocytic leukaemia.
Topics: Adolescent; Adult; Antineoplastic Combined Chemotherapy Protocols; Combined Modality Therapy; Cytarabine; Female; Humans; Idarubicin; Leukemia, Promyelocytic, Acute; Male; Mastoid; Mitoxantrone; Recurrence; Time Factors; Tretinoin | 2007 |
Significance of persistent Auer rods and cytogenetic abnormality after first cycle of therapy for acute promyelocytic leukaemia.
Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; Bone Marrow; Bone Marrow Examination; Chromosome Aberrations; Chromosomes, Human, Pair 15; Chromosomes, Human, Pair 17; Cytarabine; Daunorubicin; Humans; In Situ Hybridization, Fluorescence; Leukemia, Promyelocytic, Acute; Male; Oncogene Proteins, Fusion; Remission Induction; Translocation, Genetic; Tretinoin | 2007 |
Acute promyelocytic leukemia: a novel PML/RARalpha fusion that generates a frameshift in the RARalpha transcript and ATRA resistance.
Topics: Antineoplastic Agents; Chromosomes, Human, Pair 15; Chromosomes, Human, Pair 17; Cytarabine; Drug Resistance, Neoplasm; Female; Frameshift Mutation; Humans; Immunosuppressive Agents; Leukemia, Promyelocytic, Acute; Middle Aged; Oncogene Proteins, Fusion; Receptors, Retinoic Acid; Retinoic Acid Receptor alpha; Translocation, Genetic; Tretinoin | 2007 |
All-trans retinoic acid syndrome: another cause of drug-induced respiratory failure.
Topics: Aged; Antibiotics, Antineoplastic; Antimetabolites, Antineoplastic; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Cytarabine; Daunorubicin; Dyspnea; Female; Humans; Leukemia, Promyelocytic, Acute; Respiratory Insufficiency; Tretinoin | 2007 |
Management of acute myeloid leukaemia--5 years experience at Armed Forces Bone Marrow Transplant Centre, Rawalpindi.
Topics: Adolescent; Adult; Anthracyclines; Antineoplastic Agents; Child; Cytarabine; Disease Progression; Female; Humans; Leukemia, Myeloid, Acute; Male; Middle Aged; Military Medicine; Military Personnel; Pakistan; Retrospective Studies; Time Factors; Treatment Outcome; Tretinoin | 2007 |
[Analysis on prognosis and correlative factors of acute nonlymphocytic leukemia].
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Cytarabine; Female; Harringtonines; Humans; Leukemia, Myeloid, Acute; Male; Middle Aged; Prognosis; Tretinoin; Young Adult | 2007 |
Two cases of post-liver transplant acute myeloid leukemia in Korean adults: review of bibliographies and comparison with post-renal transplant acute myeloid leukemia.
Topics: Aged; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Cytarabine; Daunorubicin; Fatal Outcome; Female; Humans; Kidney Transplantation; Korea; Leukemia, Myeloid, Acute; Liver Transplantation; Male; Middle Aged; Treatment Outcome; Tretinoin | 2008 |
[Effectiveness of the AML-XH-99-M3 protocol for treatment of acute promyelocytic leukemia in children].
Topics: Adolescent; Antineoplastic Combined Chemotherapy Protocols; Child; Child, Preschool; Cytarabine; Daunorubicin; Etoposide; Female; Humans; Infant; Leukemia, Promyelocytic, Acute; Male; Tretinoin | 2008 |
Chemotherapy induced esophageal stricture.
Topics: Adolescent; Antineoplastic Combined Chemotherapy Protocols; Cytarabine; Daunorubicin; Down Syndrome; Esophageal Stenosis; Esophagectomy; Humans; Leukemia, Promyelocytic, Acute; Male; Mercaptopurine; Methotrexate; Tretinoin | 2009 |
Curative strategies in acute promyelocytic leukemia.
Topics: Antineoplastic Agents; Arsenic Trioxide; Arsenicals; Clinical Trials as Topic; Cytarabine; Daunorubicin; Disease-Free Survival; Growth Inhibitors; History, 20th Century; Humans; Leukemia, Promyelocytic, Acute; Middle Aged; Neoplasm Recurrence, Local; Oxides; Tretinoin | 2008 |
Existing and emerging therapeutic options for the treatment of acute myeloid leukemia.
Topics: Adenine; Adenine Nucleotides; Aminoglycosides; Anti-Inflammatory Agents, Non-Steroidal; Antibodies, Monoclonal; Antibodies, Monoclonal, Humanized; Antineoplastic Agents; Arabinonucleosides; Carbazoles; Clofarabine; Cytarabine; Dasatinib; Daunorubicin; fms-Like Tyrosine Kinase 3; Furans; Gemtuzumab; Humans; Leukemia, Myeloid, Acute; Naphthalimides; Organophosphonates; Prognosis; Protein Kinase Inhibitors; Pyrimidines; Sesquiterpenes; Staurosporine; Stem Cell Transplantation; Thiazoles; Tretinoin | 2008 |
Future research directions for the treatment of AML.
Topics: Antineoplastic Agents; Azacitidine; Biomedical Research; Carbazoles; Carboplatin; Cytarabine; Daunorubicin; Decitabine; Enzyme Inhibitors; Etoposide; Flavonoids; Furans; Humans; Leukemia, Myeloid, Acute; Mitoxantrone; Piperidines; Quinolones; Staurosporine; Topotecan; Tretinoin | 2008 |
Improved outcome for Chinese children with acute promyelocytic leukemia: a comparison of two protocols.
Topics: Adolescent; Anthracyclines; Child; Child, Preschool; Cytarabine; Female; Health Care Costs; Humans; Infant; Leukemia, Promyelocytic, Acute; Male; Treatment Outcome; Tretinoin | 2009 |
Tailoring treatment strategy for acute promyelocytic leukemia in low-income countries.
Topics: Child; China; Cytarabine; Humans; Leukemia, Promyelocytic, Acute; Tretinoin | 2009 |
Central nervous system involvement at the time of presentation in acute promyelocytic leukemia.
Topics: Adolescent; Antineoplastic Combined Chemotherapy Protocols; Central Nervous System Neoplasms; Combined Modality Therapy; Cytarabine; Daunorubicin; Female; Humans; Leukemia, Promyelocytic, Acute; Leukemic Infiltration; Mercaptopurine; Methotrexate; Oncogene Proteins, Fusion; Radiotherapy; Sarcoma, Myeloid; Tretinoin | 2010 |
Primary multiple cerebral invasion in acute promyelocytic leukemia dramatically worsened by all-trans retinoic acid.
Topics: Adrenal Cortex Hormones; Adult; Anti-Bacterial Agents; Antineoplastic Agents; Bacillus cereus; Bacterial Infections; Brain Abscess; Brain Neoplasms; Cytarabine; Female; Humans; Idarubicin; Injections, Spinal; Leukemia, Promyelocytic, Acute; Magnetic Resonance Imaging; Methotrexate; Tretinoin | 2010 |
Updates on the treatment of acute promyelocytic leukemia.
Topics: Anthracyclines; Antineoplastic Combined Chemotherapy Protocols; Benzoates; Cytarabine; Daunorubicin; Hemorrhage; Humans; Idarubicin; Leukemia, Promyelocytic, Acute; Tetrahydronaphthalenes; Tretinoin | 2010 |
CNS relapse in acute promyeloctyic leukemia.
Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; Arsenic Trioxide; Arsenicals; Bone Marrow Neoplasms; Brain Neoplasms; Chromosomes, Human, Pair 15; Chromosomes, Human, Pair 17; Cranial Irradiation; Cytarabine; Drug Administration Schedule; Female; fms-Like Tyrosine Kinase 3; Hematopoietic Stem Cell Transplantation; Humans; Idarubicin; Leukemia, Promyelocytic, Acute; Magnetic Resonance Imaging; Mercaptopurine; Methotrexate; Mutation; Nuclear Proteins; Oxides; Promyelocytic Leukemia Protein; Receptors, Retinoic Acid; Recurrence; Remission Induction; Retinoic Acid Receptor alpha; Reverse Transcriptase Polymerase Chain Reaction; Transcription Factors; Translocation, Genetic; Transplantation, Autologous; Treatment Outcome; Tretinoin; Tumor Suppressor Proteins | 2010 |
Fatal hepatitis B reactivation in an immune patient after anti-leukemic chemotherapy.
Topics: Antineoplastic Agents; Cytarabine; Fatal Outcome; Female; Hepatitis B; Humans; Idarubicin; Leukemia, Promyelocytic, Acute; Middle Aged; Tretinoin; Virus Activation | 2010 |
Treatment of acute promyelocytic leukaemia in the Jehovah's Witness population.
Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; Cytarabine; Erythropoietin; Female; Hemoglobins; Humans; Jehovah's Witnesses; Leukemia, Promyelocytic, Acute; Male; Mercaptopurine; Methotrexate; Middle Aged; Remission Induction; Treatment Outcome; Tretinoin | 2011 |
Renal cell carcinoma and acute promyelocytic leukemia: a nonrandom association?
Topics: Adenocarcinoma; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Renal Cell; Colonic Neoplasms; Colonic Polyps; Cytarabine; Daunorubicin; Doxorubicin; Female; Humans; Idarubicin; Indoles; Kidney Neoplasms; Leukemia, Promyelocytic, Acute; Lung Neoplasms; Male; Mercaptopurine; Methotrexate; Middle Aged; Neoplasms, Second Primary; Pyrroles; Remission Induction; Sunitinib; Time Factors; Tretinoin | 2010 |
The role of standard-dose cytarabine in children with acute promyelocytic leukemia: a single-center experience.
Topics: Adolescent; Antimetabolites, Antineoplastic; Antineoplastic Combined Chemotherapy Protocols; Child; Child, Preschool; Cytarabine; Daunorubicin; Disease-Free Survival; Female; Humans; Infant; Kaplan-Meier Estimate; Leukemia, Promyelocytic, Acute; Male; Mercaptopurine; Methotrexate; Treatment Outcome; Tretinoin | 2011 |
Stochastic acquisition of a stem cell-like state and drug tolerance in leukemia cells stressed by radiation.
Topics: Animals; Antimetabolites, Antineoplastic; Antimicrobial Cationic Peptides; Cytarabine; Drug Resistance, Neoplasm; Gamma Rays; HL-60 Cells; Humans; Leukemia, Promyelocytic, Acute; Mice; Mice, Inbred NOD; Neoplastic Stem Cells; Radiation Tolerance; Reactive Oxygen Species; Tretinoin | 2011 |
Acquired protein C deficiency in a child with acute myelogenous leukemia, splenic, renal, and intestinal infarction.
Topics: Antineoplastic Combined Chemotherapy Protocols; Child; Cholecystectomy; Cytarabine; Etoposide; Fibrin Fibrinogen Degradation Products; Fibrinogen; Gallbladder; Heparin, Low-Molecular-Weight; Humans; Idarubicin; Infarction; Kidney; Lebanon; Leukemia, Myeloid, Acute; Male; Protein C; Protein C Deficiency; Remission Induction; Splenectomy; Splenic Infarction; Thrombosis; Tretinoin | 2011 |
Successful treatment of acute promyelocytic leukemia in a patient on hemodialysis.
Topics: Antineoplastic Combined Chemotherapy Protocols; Cytarabine; Daunorubicin; Female; Humans; Idarubicin; Kidney Failure, Chronic; Leukemia, Promyelocytic, Acute; Middle Aged; Mitomycin; Remission Induction; Renal Dialysis; Tretinoin | 2011 |
Massive postpartum hemorrhage after chemotherapy in a patient with acute promyelocytic leukemia.
Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; Cytarabine; Female; Humans; Idarubicin; Induction Chemotherapy; Leukemia, Promyelocytic, Acute; Postpartum Hemorrhage; Pregnancy; Pregnancy Complications, Neoplastic; Tretinoin | 2011 |
Long-term remission in a case of acute promyelocytic leukemia patient with marked myelofibrosis treated with arsenic trioxide, all-trans retinoic acid and consolidation therapy with daunorubicin plus cytarabine.
Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; Arsenic Trioxide; Arsenicals; Consolidation Chemotherapy; Cytarabine; Daunorubicin; Female; Humans; Leukemia, Promyelocytic, Acute; Oxides; Primary Myelofibrosis; Remission Induction; Survivors; Tretinoin | 2012 |
Long-term outcome and prognostic factors of elderly patients with acute promyelocytic leukemia.
Topics: Adult; Aged; Anthracyclines; Antineoplastic Combined Chemotherapy Protocols; Cytarabine; Disease-Free Survival; Female; Follow-Up Studies; Humans; Japan; Leukemia, Promyelocytic, Acute; Male; Middle Aged; Prognosis; Recurrence; Treatment Outcome; Tretinoin | 2012 |
Outcome of elderly patients with acute promyelocytic leukemia: results of the German Acute Myeloid Leukemia Cooperative Group.
Topics: Age Factors; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Arsenic Trioxide; Arsenicals; Bone Marrow; Cytarabine; Daunorubicin; Disease-Free Survival; Female; Follow-Up Studies; Germany; Humans; Kaplan-Meier Estimate; Leukemia, Promyelocytic, Acute; Leukocyte Count; Maintenance Chemotherapy; Male; Middle Aged; Mitoxantrone; Multicenter Studies as Topic; Oxides; Prognosis; Randomized Controlled Trials as Topic; Remission Induction; Risk; Thioguanine; Treatment Outcome; Tretinoin | 2013 |
Multiplexed mAbs: a new strategy in preclinical time-domain imaging of acute myeloid leukemia.
Topics: Animals; Anthracyclines; Antibodies, Monoclonal; Antineoplastic Combined Chemotherapy Protocols; CD11b Antigen; CD11c Antigen; Cell Line, Tumor; Cytarabine; Fluorescent Dyes; Green Fluorescent Proteins; HL-60 Cells; Humans; Immunophenotyping; Leukemia, Myeloid, Acute; Leukemia, Promyelocytic, Acute; Luminescent Measurements; Mice; Mice, Inbred NOD; Mice, Knockout; Mice, SCID; Optical Imaging; Tretinoin; Valproic Acid; Xenograft Model Antitumor Assays | 2013 |
A case report of acute myeloid leukemia after liver transplantation.
Topics: Antineoplastic Combined Chemotherapy Protocols; Arsenic Trioxide; Arsenicals; Bone Marrow; Cytarabine; Daunorubicin; Hepatitis B; Humans; Leukemia, Myeloid, Acute; Liver Cirrhosis; Liver Transplantation; Male; Middle Aged; Mitoxantrone; Oxides; Tretinoin | 2013 |
All-trans-retinoic acid-induced scrotal ulcers in a patient with acute promyelocytic leukemia.
Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; Cytarabine; Daunorubicin; Drug Eruptions; Humans; Leukemia, Promyelocytic, Acute; Male; Scrotum; Skin Ulcer; Tretinoin | 2013 |
Long-term efficacy of low-dose all-trans retinoic acid plus minimal chemotherapy induction followed by the addition of intravenous arsenic trioxide post-remission therapy in newly diagnosed acute promyelocytic leukaemia.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Arsenic Trioxide; Arsenicals; China; Consolidation Chemotherapy; Cytarabine; Daunorubicin; Dexamethasone; Drug Evaluation; Female; Harringtonines; Homoharringtonine; Humans; Idarubicin; Infusions, Intravenous; Kaplan-Meier Estimate; Leukemia, Promyelocytic, Acute; Male; Methotrexate; Middle Aged; Neoplasm, Residual; Oncogene Proteins, Fusion; Oxides; Recurrence; Remission Induction; Retrospective Studies; Salvage Therapy; Treatment Outcome; Tretinoin; Young Adult | 2014 |
[Pulmonary differentiation -/ATRA syndrome within the scope of therapy of acute promyelocytic leukemia (APL)].
Topics: Antineoplastic Combined Chemotherapy Protocols; Cytarabine; Daunorubicin; Diagnosis, Differential; Dyspnea; Female; Follow-Up Studies; Humans; Induction Chemotherapy; Leukemia, Promyelocytic, Acute; Middle Aged; Mitoxantrone; Pleural Effusion; Pulmonary Edema; Thioguanine; Tomography, X-Ray Computed; Tretinoin | 2014 |
Prognostic value of IDH1 mutations identified with PCR-RFLP assay in acute myeloid leukemia patients.
Topics: Adolescent; Adult; Antineoplastic Combined Chemotherapy Protocols; Cytarabine; DNA Mutational Analysis; Doxorubicin; Female; Genetic Association Studies; Humans; Isocitrate Dehydrogenase; Leukemia, Myeloid, Acute; Male; Middle Aged; Mitoxantrone; Mutation; Polymerase Chain Reaction; Polymorphism, Restriction Fragment Length; Prognosis; Treatment Outcome; Tretinoin; Young Adult | 2014 |
Sensitivity of MLL-rearranged AML cells to all-trans retinoic acid is associated with the level of H3K4me2 in the RARα promoter region.
Topics: Antineoplastic Combined Chemotherapy Protocols; Cell Cycle Checkpoints; Cell Differentiation; Cytarabine; DNA-Binding Proteins; Drug Synergism; Histone-Lysine N-Methyltransferase; Histones; Humans; Leukemia, Myeloid, Acute; Myeloid-Lymphoid Leukemia Protein; Neoplasm Proteins; Nuclear Proteins; Promoter Regions, Genetic; Proto-Oncogene Proteins; Receptors, Retinoic Acid; Retinoic Acid Receptor alpha; Trans-Activators; Transcriptional Activation; Transcriptional Elongation Factors; Tretinoin | 2014 |
Acute promyelocytic leukemia in patients aged >70 years: the cure beyond the age.
Topics: Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Cytarabine; Etoposide; Female; Follow-Up Studies; Humans; Idarubicin; Interferon-alpha; Leukemia, Promyelocytic, Acute; Male; Mercaptopurine; Mitoxantrone; Remission Induction; Survival Analysis; Time Factors; Treatment Outcome; Tretinoin | 2015 |
A prospective, observational study of added medium-dose cytosine arabinoside versus As2O3 for elderly patients with acute promyelocytic leukemia.
Topics: Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Arsenic Trioxide; Arsenicals; Cytarabine; Daunorubicin; Disease-Free Survival; Female; Humans; Leukemia, Promyelocytic, Acute; Male; Oxides; Polymerase Chain Reaction; Prospective Studies; Survival Rate; Tretinoin | 2014 |
Effects of cytarabine on activation of human T cells - cytarabine has concentration-dependent effects that are modulated both by valproic acid and all-trans retinoic acid.
Topics: ADP-ribosyl Cyclase 1; Antigens, CD; Antigens, Differentiation, T-Lymphocyte; CD4 Antigens; CD8 Antigens; Cell Membrane; Cell Proliferation; Cell Survival; Cells, Cultured; Cytarabine; Cytokines; Dose-Response Relationship, Drug; Drug Interactions; Fas Ligand Protein; HSP70 Heat-Shock Proteins; HSP90 Heat-Shock Proteins; Humans; Lectins, C-Type; Lymphocyte Activation; T-Lymphocytes; TNF-Related Apoptosis-Inducing Ligand; Tretinoin; Valproic Acid | 2015 |
Chemotherapy-free treatment of acute promyelocytic leukemia.
Topics: Anthracyclines; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Arsenic Trioxide; Arsenicals; Cytarabine; Humans; Leukemia, Promyelocytic, Acute; Oxides; Tretinoin | 2015 |
High event-free survival rate with minimum-dose-anthracycline treatment in childhood acute promyelocytic leukaemia: a nationwide prospective study by the Japanese Paediatric Leukaemia/Lymphoma Study Group.
Topics: Adolescent; Anthracyclines; Child; Child, Preschool; Consolidation Chemotherapy; Cytarabine; Disease-Free Survival; Humans; Induction Chemotherapy; Infant; Japan; Leukemia, Promyelocytic, Acute; Maintenance Chemotherapy; Male; Prospective Studies; Survival Rate; Treatment Outcome; Tretinoin | 2016 |
Huang ME, Ye YC, Chen SR, et al. Use of all-trans retinoic acid in the treatment of acute promyelocytic leukemia. Blood. 1988;72(2):567-572.
Topics: Blood Coagulation; Cytarabine; Female; Humans; Leukemia, Promyelocytic, Acute; Male; Neoplasm Proteins; Remission Induction; Tretinoin | 2016 |
Bilateral Retinal Hemorrhages in a Young Man.
Topics: Adult; Antimetabolites, Antineoplastic; Blood Cell Count; Cytarabine; Humans; Leukemia, Promyelocytic, Acute; Male; Retinal Hemorrhage; Retinal Neoplasms; Tretinoin; Visual Acuity | 2017 |
Outcome of Lower-Risk Patients With Myelodysplastic Syndromes Without 5q Deletion After Failure of Erythropoiesis-Stimulating Agents.
Topics: Aged; Aged, 80 and over; Anemia; Antilymphocyte Serum; Antineoplastic Agents; Arsenic; Azacitidine; Chromosome Deletion; Chromosomes, Human, Pair 5; Cyclosporine; Cytarabine; Decitabine; Disease Progression; Enzyme Inhibitors; Erythrocyte Transfusion; Female; Hematinics; Humans; Hydroxyurea; Immunologic Factors; Lenalidomide; Leukemia, Myeloid, Acute; Male; Middle Aged; Myelodysplastic Syndromes; Recurrence; Retreatment; Retrospective Studies; Risk Factors; Survival Rate; Thalidomide; Treatment Failure; Tretinoin; Valproic Acid | 2017 |
Systemic Metabolomic Profiling of Acute Myeloid Leukemia Patients before and During Disease-Stabilizing Treatment Based on All-Trans Retinoic Acid, Valproic Acid, and Low-Dose Chemotherapy.
Topics: Aged; Aged, 80 and over; Amino Acids; Cytarabine; Drug Therapy; Female; Humans; Hydroxyurea; Leukemia, Myeloid, Acute; Lipid Metabolism; Male; Mercaptopurine; Metabolomics; Middle Aged; Treatment Outcome; Tretinoin; Valproic Acid | 2019 |
Two successful deliveries of healthy children by a young woman diagnosed and treated during induction and relapsed therapy for acute promyelocytic leukemia.
Topics: Antineoplastic Combined Chemotherapy Protocols; Arsenic Trioxide; Cytarabine; Female; Hematopoietic Stem Cell Transplantation; Humans; Idarubicin; Induction Chemotherapy; Leukemia, Promyelocytic, Acute; Pregnancy; Recurrence; Tretinoin; Young Adult | 2020 |
Acute myeloid leukemia with a severe coagulopathy and t(8;16)(p11;p13).
Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; Blood Coagulation Disorders; Chromosomes, Human, Pair 16; Chromosomes, Human, Pair 8; Cytarabine; Daunorubicin; Dexamethasone; Gemtuzumab; Humans; Leukemia, Myeloid, Acute; Male; Translocation, Genetic; Tretinoin | 2021 |
Renin angiotensin system genes are biomarkers for personalized treatment of acute myeloid leukemia with Doxorubicin as well as etoposide.
Topics: Antineoplastic Combined Chemotherapy Protocols; Biomarkers; Cell Line, Tumor; Computer Simulation; Cytarabine; Datasets as Topic; Doxorubicin; Drug Resistance, Neoplasm; Etoposide; Gene Ontology; Humans; Inhibitory Concentration 50; Kaplan-Meier Estimate; Leukemia, Myeloid, Acute; Nonlinear Dynamics; Precision Medicine; Prognosis; Real-Time Polymerase Chain Reaction; Renin-Angiotensin System; Tretinoin | 2020 |
Long-term follow-up results of cytarabine-containing chemotherapy for acute promyelocytic leukemia.
Topics: Anthracyclines; Antineoplastic Combined Chemotherapy Protocols; Arsenic Trioxide; Cytarabine; Follow-Up Studies; Humans; Idarubicin; Leukemia, Promyelocytic, Acute; Recurrence; Remission Induction; Treatment Outcome; Tretinoin | 2022 |