cytarabine and tosedostat

cytarabine has been researched along with tosedostat in 5 studies

Research

Studies (5)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's3 (60.00)24.3611
2020's2 (40.00)2.80

Authors

AuthorsStudies
Burnett, A; Hewamana, S; Jenkins, C; Krige, D; Pepper, C1
Advani, AS; Charman, A; Cortes, J; Feldman, E; Kantarjian, H; Rizzieri, D; Spruyt, R; Toal, M; Yee, K1
Becker, PS; Dean, C; Deeg, HJ; Estey, E; Hendrie, P; Mawad, R; Myint, H; Pagel, JM; Sandhu, V; Scott, B; Singer, JW; Walter, R; Wang, L; Wood, BL1
Candoni, A; Clavio, M; Dennis, M; Giannini, B; Gibellini, D; Gilkes, A; Isidori, A; Loscocco, F; Mianulli, AM; Musuraca, G; Navari, M; Piccaluga, PP; Rocchi, M; Sensi, A; Visani, G; Zuffa, E1
Ariti, C; Burnett, A; Clark, RE; Copland, M; Dennis, M; Greaves, P; Hemmaway, C; Hills, R; Russell, N; Severinsen, MT; Thomas, I1

Trials

3 trial(s) available for cytarabine and tosedostat

ArticleYear
Two dosing regimens of tosedostat in elderly patients with relapsed or refractory acute myeloid leukaemia (OPAL): a randomised open-label phase 2 study.
    The Lancet. Oncology, 2013, Volume: 14, Issue:4

    Topics: Aged; Aged, 80 and over; Anemia, Refractory; Cytarabine; Disease-Free Survival; Female; Glycine; Humans; Hydroxamic Acids; Leukemia, Monocytic, Acute; Male; Middle Aged; Recurrence; Remission Induction

2013
Phase II study of tosedostat with cytarabine or decitabine in newly diagnosed older patients with acute myeloid leukaemia or high-risk MDS.
    British journal of haematology, 2016, Volume: 172, Issue:2

    Topics: Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Azacitidine; Cytarabine; Decitabine; Female; Glycine; Humans; Hydroxamic Acids; Leukemia, Myeloid, Acute; Male; Middle Aged; Myelodysplastic Syndromes; Remission Induction; Survival Analysis; Treatment Outcome

2016
A randomised evaluation of low-dose cytosine arabinoside (ara-C) plus tosedostat versus low-dose ara-C in older patients with acute myeloid leukaemia: results of the LI-1 trial.
    British journal of haematology, 2021, Volume: 194, Issue:2

    Topics: Age Factors; Aged; Aged, 80 and over; Antimetabolites, Antineoplastic; Antineoplastic Combined Chemotherapy Protocols; Cytarabine; Enzyme Inhibitors; Female; Glycine; Humans; Hydroxamic Acids; Leukemia, Myeloid, Acute; Male; Middle Aged; Survival Analysis

2021

Other Studies

2 other study(ies) available for cytarabine and tosedostat

ArticleYear
Aminopeptidase inhibition by the novel agent CHR-2797 (tosedostat) for the therapy of acute myeloid leukemia.
    Leukemia research, 2011, Volume: 35, Issue:5

    Topics: Adult; Aminopeptidases; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Cell Culture Techniques; Cytarabine; Drug Evaluation, Preclinical; Enzyme Inhibitors; Female; Glycine; Humans; Hydroxamic Acids; Leukemia, Myeloid, Acute; Male; Middle Aged; Tumor Cells, Cultured; Young Adult

2011
Gene expression profile predicts response to the combination of tosedostat and low-dose cytarabine in elderly AML.
    Blood advances, 2020, 10-27, Volume: 4, Issue:20

    Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Cytarabine; Glycine; Humans; Hydroxamic Acids; Leukemia, Myeloid, Acute; Microarray Analysis; Transcriptome

2020