cytarabine and thioinosine

cytarabine has been researched along with thioinosine in 34 studies

Research

Studies (34)

TimeframeStudies, this research(%)All Research%
pre-199021 (61.76)18.7374
1990's7 (20.59)18.2507
2000's4 (11.76)29.6817
2010's2 (5.88)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Dorr, RT; Iyengar, BS; Remers, WA1
Revankar, GR; Robins, RK; Rousseau, RJ; Srivastava, PC1
González-Díaz, H; Orallo, F; Quezada, E; Santana, L; Uriarte, E; Viña, D; Yáñez, M1
Berg, P; Krowke, R; Merker, HJ1
Jakobs, ES; Lauzon, GJ; Paterson, AR; Weinstein, WM1
Bibi, O; Cabantchik, ZI; Heichal, O; Katz, J1
Hutchison, DJ; Otter, GM; Schmid, FA; Stock, CC1
Hirano, M; Imai, K; Imamura, K; Ishiguro, J; Kamiya, T; Koie, K; Nishiwaki, H; Ohno, R; Sako, F; Uetani, T1
Cass, CE; Muzik, H; Paterson, AR1
Mitsumoto, Y; Mohri, T; Ohkubo, T1
Brocklebank, AM; Cass, CE; Craik, JD; Jamieson, GP; McAdam, DP; Paterson, AR; Robins, MJ; Sawyer, WH; Snook, MB; Wiley, JS1
Hamazaki, M; Higashigawa, M; Hori, H; Ido, M; Kawasaki, H; Kuwabara, H; Ohkubo, T; Sakurai, M; Taniguchi, K1
Jamieson, GP; Snook, MB; Wiley, JS1
Akiyama, Y; Kiriyama, Y; Kitoh, T; Kubota, M; Mikawa, H; Takimoto, T; Tanizawa, A1
Johnson, EM; Wallace, TL1
Bertoncello, I; Bradley, TR; Jamieson, GP; Snook, MB; Wiley, JS1
Belt, JA; Noel, LD1
Finch, LR; Jamieson, GP; Snook, M; Wiley, JS1
Hines, LH; Rathmell, JP; White, JC1
Ono, R1
Steuber, CP1
Kanner, N; Koren, R; Shohami, E1
Jones, SP; Sawyer, WH; Wiley, JS1
Jones, SP; Paterson, AR; Sawyer, WH; Wiley, JS1
Maekawa, T; Omine, M; Tsuchiya, J1
Kato, Y; Suzuki, H; Yamada, K1
Ezaki, K; Kato, Y; Kawashima, K; Kobayashi, M; Kodera, Y; Minami, S; Morishima, Y; Morishita, T; Nishiwaki, H; Ogura, M; Ohara, K; Ohno, R; Suzuki, H; Takeyama, H; Tanimoto, M; Watanabe, E; Yamada, H; Yamada, K; Yamaguchi, H; Yokomaku, S; Yoshikawa, S1
Goz, B; Jeffs, L1
Brocklebank, AM; Buolamwini, JK; Jamieson, GP; Paterson, AR; Sawyer, WH; Snook, MB; Wiley, JS1
Cass, CE; Clarke, ML; Damaraju, VL; Lang, T; Mowles, D; Smith, KM; Tackaberry, T; Tomkinson, B; Young, JD; Zhang, J1
Hiura, T; Ishikawa, M; Kanno, S; Koiwai, K; Ohtake, T; Suzuki, H; Ujibe, M1
Graves, LM; Huang, M; Leisewitz, AV; Wang, Y; Yang, J; Zimmerman, EI1
Denich, D; Gärtner, F; Ohmle, B; Parmar, S; Pitterle, K; Seeringer, A; Stingl, JC; Syrovets, T1
Anderson, JT; Baker, SD; Fu, Q; Hu, S; Sparreboom, A1

Reviews

1 review(s) available for cytarabine and thioinosine

ArticleYear
Therapy in childhood acute nonlymphocytic leukemia (ANLL). Evolution of current concepts of chemotherapy.
    The American journal of pediatric hematology/oncology, 1981,Winter, Volume: 3, Issue:4

    Topics: Acute Disease; Adolescent; Adult; Asparaginase; Azauridine; Child; Child, Preschool; Cyclophosphamide; Cytarabine; Daunorubicin; Drug Therapy, Combination; Humans; Leukemia; Prednisone; Thioguanine; Thioinosine; Vincristine

1981

Other Studies

33 other study(ies) available for cytarabine and thioinosine

ArticleYear
Additional nucleotide derivatives of mitosenes. Synthesis and activity against parental and multidrug resistant L1210 leukemia.
    Journal of medicinal chemistry, 1991, Volume: 34, Issue:7

    Topics: Animals; Antineoplastic Agents; Cell Line; Chemical Phenomena; Chemistry; Leukemia L1210; Mice; Mitomycin; Mitomycins; Nucleotides

1991
Synthesis and biological evaluation of certain 2'-deoxy-beta-D-ribo- and -beta-D-arabinofuranosyl nucleosides of purine-6-carboxamide and 4,8-diaminopyrimido[5,4-d]pyrimidine.
    Journal of medicinal chemistry, 1981, Volume: 24, Issue:4

    Topics: Animals; Antibody Formation; Arabinonucleosides; Deoxyribonucleosides; Immunity, Cellular; Immunosuppressive Agents; Mice; Structure-Activity Relationship

1981
Quantitative structure-activity relationship and complex network approach to monoamine oxidase A and B inhibitors.
    Journal of medicinal chemistry, 2008, Nov-13, Volume: 51, Issue:21

    Topics: Computational Biology; Drug Design; Humans; Isoenzymes; Molecular Structure; Monoamine Oxidase; Monoamine Oxidase Inhibitors; Quantitative Structure-Activity Relationship

2008
Effects of cytosine arabinoside, 6-aminonicotinamide, and 6-mercaptopurine riboside on ectoderm and mesoderm of mouse limb buds.
    Teratology, 1977, Volume: 15, Issue:2

    Topics: 6-Aminonicotinamide; Animals; Cytarabine; DNA; Ectoderm; Embryo, Mammalian; Extremities; Female; Glucose; In Vitro Techniques; Inosine; Maternal-Fetal Exchange; Mesoderm; Mice; Niacinamide; Phosphates; Pregnancy; RNA; Teratogens; Thioinosine; Time Factors

1977
Drug sequence-dependent toxicity and small bowel mucosal injury in mice treated with low doses of 3-deazauridine and 1-beta-D-arabinofuranosylcytosine.
    Cancer research, 1979, Volume: 39, Issue:6 Pt 1

    Topics: 3-Deazauridine; Animals; Cytarabine; Female; Intestinal Mucosa; Intestine, Small; Male; Mice; Thioinosine; Time Factors; Uridine

1979
Nucleoside transport in mammalian cell membranes. III. Kinetic and chemical modification studies of cytosine-arabinoside and uridine transport in hamster cells in culture.
    The Journal of membrane biology, 1978, Mar-10, Volume: 39, Issue:2-3

    Topics: Affinity Labels; Biological Transport, Active; Cell Line; Cytarabine; Ethylmaleimide; Kinetics; Phenylmercury Compounds; Thioinosine; Uridine

1978
Deveopment of resistance to combinations of six antimetabolites in mice with L1210 leukemia.
    Cancer treatment reports, 1976, Volume: 60, Issue:1

    Topics: Animals; Antimetabolites, Antineoplastic; Cytarabine; Drug Administration Schedule; Drug Resistance; Drug Therapy, Combination; Fluorouracil; Leukemia L1210; Male; Mercaptopurine; Methotrexate; Mice; Mice, Inbred C57BL; Mice, Inbred CBA; Thioguanine; Thioinosine

1976
Daunorubicin, cytosine arabinoside, 6-mercaptopurine riboside, and prednisolone (DCMP) combination chemotherapy for acute myelogenous leukemia in adults.
    Cancer, 1975, Volume: 36, Issue:6

    Topics: Adolescent; Adult; Age Factors; Cytarabine; Daunorubicin; Drug Therapy, Combination; Female; Humans; Inosine; Leukemia, Myeloid, Acute; Male; Middle Aged; Prednisolone; Remission, Spontaneous; Thioinosine

1975
Combination therapy of mouse leukemia L1210 by 1-beta-D-arabinofuranosylcytosine and 6-[(4-nitrobenzyl)thio]-9-beta-D-ribofuranosylpurine.
    Cancer research, 1975, Volume: 35, Issue:5

    Topics: Animals; Antineoplastic Agents; Cells, Cultured; Cytarabine; Drug Synergism; Drug Therapy, Combination; Female; Half-Life; Inosine; Leukemia L1210; Mice; Nitrobenzenes; Sulfides; Thioinosine

1975
Characterization of the uptake of adenosine by cultured rat hippocampal cells and inhibition of the uptake by xanthine derivatives.
    Neuroscience letters, 1991, Dec-09, Volume: 133, Issue:2

    Topics: 2-Chloroadenosine; Adenosine; Affinity Labels; Animals; Biological Transport; Caffeine; Cells, Cultured; Cytarabine; Dipyridamole; Embryo, Mammalian; Hippocampus; Kinetics; Neuroglia; Neurons; Pentoxifylline; Rats; Sodium; Theophylline; Thioinosine; Tritium; Xanthines

1991
A new fluorescent probe for the equilibrative inhibitor-sensitive nucleoside transporter. 5'-S-(2-aminoethyl)-N6-(4-nitrobenzyl)-5'-thioadenosine (SAENTA)-chi 2-fluorescein.
    The Biochemical journal, 1991, Feb-01, Volume: 273 ( Pt 3)

    Topics: Adenosine; Affinity Labels; Carrier Proteins; Cell Line; Cytarabine; Flow Cytometry; Fluorescent Dyes; Humans; Kinetics; Membrane Proteins; Molecular Structure; Nucleoside Transport Proteins; Spectrometry, Fluorescence; Thioinosine; Thionucleosides

1991
Membrane transport of 1-beta-D-arabinofuranosylcytosine and accumulation of 1-beta-D-arabinofuranosylcytosine 5'-triphosphate in P388 murine leukemic cells resistant to vincristine.
    Leukemia research, 1991, Volume: 15, Issue:4

    Topics: Animals; Arabinofuranosylcytosine Triphosphate; Binding Sites; Biological Transport; Cell Membrane; Cytarabine; Drug Resistance; Leukemia P388; Mice; Mice, Inbred Strains; Thioinosine; Tumor Cells, Cultured; Vincristine

1991
Saturation of intracellular cytosine arabinoside triphosphate accumulation in human leukemic blast cells.
    Leukemia research, 1990, Volume: 14, Issue:5

    Topics: Acute Disease; Arabinofuranosylcytosine Triphosphate; Arabinonucleotides; Binding Sites; Biological Transport; Cell Membrane; Cytarabine; Deoxycytidine Kinase; Extracellular Space; Humans; Leukemia; Lymphocytes; Nucleosides; Phosphorylation; Thioinosine; Tumor Cells, Cultured

1990
Characterization of nucleoside transport during leukemic cell differentiation.
    Advances in experimental medicine and biology, 1989, Volume: 253B

    Topics: Biological Transport; Cell Differentiation; Cytarabine; Deoxycytidine Kinase; Dipyridamole; Humans; Inosine; Leukemia, Promyelocytic, Acute; Precursor Cell Lymphoblastic Leukemia-Lymphoma; T-Lymphocytes; Tetradecanoylphorbol Acetate; Thioinosine; Tretinoin; Tumor Cells, Cultured

1989
Cytosine arabinoside kills postmitotic neurons: evidence that deoxycytidine may have a role in neuronal survival that is independent of DNA synthesis.
    The Journal of neuroscience : the official journal of the Society for Neuroscience, 1989, Volume: 9, Issue:1

    Topics: Animals; Antineoplastic Agents; Cell Survival; Chick Embryo; Ciliary Body; Cytarabine; Deoxycytidine; DNA; Dose-Response Relationship, Drug; Ganglia, Spinal; Insulin; Mitosis; Nerve Growth Factors; Neurons; Parasympathetic Nervous System; Thioinosine

1989
Transport and metabolism of 1-beta-D-arabinofuranosylcytosine in human ovarian adenocarcinoma cells.
    Cancer research, 1989, Jan-15, Volume: 49, Issue:2

    Topics: Adenocarcinoma; Aged; Arabinofuranosylcytosine Triphosphate; Binding Sites; Cell Line; Cytarabine; Female; Humans; Leukemia, Myelomonocytic, Acute; Male; Ovarian Neoplasms; Thioinosine

1989
Isolation and characterization of a mutant of L1210 murine leukemia deficient in nitrobenzylthioinosine-insensitive nucleoside transport.
    The Journal of biological chemistry, 1988, Sep-25, Volume: 263, Issue:27

    Topics: Animals; Biological Transport; Carrier Proteins; Cytarabine; Floxuridine; Inosine; Leukemia L1210; Membrane Proteins; Mice; Mutation; Nucleoside Transport Proteins; Nucleosides; Thioinosine; Thymidine; Tubercidin; Tumor Cells, Cultured; Uridine

1988
Degradation of 1-beta-D-arabinofuranosylcytosine 5'-triphosphate in human leukemic myeloblasts and lymphoblasts.
    Cancer research, 1987, Jun-15, Volume: 47, Issue:12

    Topics: Arabinofuranosylcytosine Triphosphate; Arabinonucleotides; Cytarabine; DCMP Deaminase; Guanosine; Half-Life; Humans; Kinetics; Leukemia, Lymphoid; Leukemia, Myeloid, Acute; Lymphocytes; Phosphorylation; Thioinosine; Thionucleosides

1987
Inhibition of 1-beta-D-arabinofuranosylcytosine transport and net accumulation by teniposide and etoposide in Ehrlich ascites cells and human leukemic blasts.
    Cancer research, 1985, Volume: 45, Issue:7

    Topics: Animals; Binding Sites; Biological Transport; Carcinoma, Ehrlich Tumor; Cells, Cultured; Cytarabine; Etoposide; Humans; Leukemia; Male; Mice; Mice, Inbred Strains; Podophyllotoxin; Teniposide; Thioinosine; Tritium

1985
[Combination chemotherapy for acute myelogenous leukemia in adults (author's transl)].
    Nihon Ketsueki Gakkai zasshi : journal of Japan Haematological Society, 1974, Volume: 37, Issue:5

    Topics: Adolescent; Adult; Antineoplastic Agents; Cyclophosphamide; Cytarabine; Daunorubicin; Drug Therapy, Combination; Humans; Leukemia, Myeloid, Acute; Mercaptopurine; Middle Aged; Prednisolone; Remission, Spontaneous; Thioinosine

1974
S-substituted derivatives of 6-mercaptopurine ribosides interact both with the transport and metabolic phosphorylation of uridine by virus-transformed hamster fibroblasts.
    Biochimica et biophysica acta, 1980, Sep-02, Volume: 601, Issue:1

    Topics: Animals; Cell Line; Cell Transformation, Viral; Cricetinae; Cytarabine; Deoxyglucose; Inosine; Kinetics; Mesocricetus; Phosphorylation; Sarcoma Viruses, Murine; Thioinosine; Uridine

1980
Cytosine arabinoside transport by human leukaemic cells.
    European journal of cancer & clinical oncology, 1983, Volume: 19, Issue:8

    Topics: Acute Disease; Adolescent; Adult; Aged; Biological Transport; Cell Membrane; Child; Child, Preschool; Cytarabine; Deoxycytidine; Humans; Infant; Kinetics; Leukemia; Leukocytes; Middle Aged; Phloretin; Thioinosine

1983
Cytosine arabinoside influx and nucleoside transport sites in acute leukemia.
    The Journal of clinical investigation, 1982, Volume: 69, Issue:2

    Topics: Acute Disease; Adolescent; Adult; Aged; Binding Sites; Bone Marrow Cells; Carrier Proteins; Cell Transformation, Neoplastic; Child; Child, Preschool; Cytarabine; Humans; Infant; Leukemia; Leukemia, Myeloid; Leukemia, Myeloid, Acute; Leukocytes; Middle Aged; Nucleosides; Thioinosine; Time Factors

1982
Clinical implications of cytokinetic and biochemical features of acute leukemia cells.
    Nihon Ketsueki Gakkai zasshi : journal of Japan Haematological Society, 1980, Volume: 43, Issue:6

    Topics: Acute Disease; Cell Transformation, Neoplastic; Cytarabine; Daunorubicin; Humans; Leukemia; Prednisolone; Thioinosine

1980
Phase III study of N4-behenoyl-l-beta-D-arabinofuranosylcytosine in adult acute leukemia-BH-AC-DMP therapy.
    Nihon Ketsueki Gakkai zasshi : journal of Japan Haematological Society, 1980, Volume: 43, Issue:6

    Topics: Acute Disease; Adolescent; Adult; Cytarabine; Daunorubicin; Female; Humans; Leukemia; Male; Middle Aged; Prednisolone; Thioinosine

1980
[DCTP and DCMP two step therapy in acute non-lymphocytic leukemia (author's transl)].
    [Rinsho ketsueki] The Japanese journal of clinical hematology, 1980, Volume: 21, Issue:1

    Topics: Acute Disease; Adolescent; Adult; Aged; Antineoplastic Agents; Cytarabine; Daunorubicin; Drug Therapy, Combination; Humans; Leukemia; Middle Aged; Prednisolone; Thioguanine; Thioinosine

1980
The enhancement of the frequency of resistance to N-phosphonoacetyl-L-aspartate and methotrexate by 1-beta-D-arabinofuranosylcytosine: the effect of dipyridamole.
    The Journal of pharmacology and experimental therapeutics, 1994, Volume: 270, Issue:2

    Topics: Animals; Aspartic Acid; Cell Line, Transformed; Cricetinae; Cytarabine; Dipyridamole; Drug Resistance; Drug Synergism; Humans; Methotrexate; Nucleosides; Phosphonoacetic Acid; Thioinosine

1994
Flow cytometric quantitation of nucleoside transporter sites on human leukemic cells.
    Cytometry, 1993, Volume: 14, Issue:1

    Topics: Adenosine; Binding Sites; Carrier Proteins; Cell Line; Cytarabine; Fluoresceins; Humans; Leukemia, Myeloid; Ligands; Membrane Proteins; Nucleoside Transport Proteins; Purine Nucleosides; Thioinosine; Thionucleosides

1993
The role of human nucleoside transporters in cellular uptake of 4'-thio-beta-D-arabinofuranosylcytosine and beta-D-arabinosylcytosine.
    Molecular pharmacology, 2006, Volume: 70, Issue:1

    Topics: Animals; Arabinonucleosides; Biological Transport; Cell Line, Tumor; Cell Survival; Cytarabine; Cytidine; Dose-Response Relationship, Drug; Equilibrative-Nucleoside Transporter 2; Female; HeLa Cells; Humans; Membrane Potentials; Nucleoside Transport Proteins; Oocytes; Saccharomyces cerevisiae; Thioinosine; Transfection; Tritium; Uridine; Xenopus laevis

2006
Characterization of resistance to cytosine arabinoside (Ara-C) in NALM-6 human B leukemia cells.
    Clinica chimica acta; international journal of clinical chemistry, 2007, Volume: 377, Issue:1-2

    Topics: Cell Line, Tumor; Cell Survival; Cytarabine; Cytidine Deaminase; Cytoprotection; Deoxycytidine Kinase; Dipyridamole; Drug Resistance, Neoplasm; Gene Expression; Humans; Leukemia; RNA, Messenger; Thioinosine

2007
Identification of a novel point mutation in ENT1 that confers resistance to Ara-C in human T cell leukemia CCRF-CEM cells.
    FEBS letters, 2009, Jan-22, Volume: 583, Issue:2

    Topics: Amino Acid Sequence; Animals; Antimetabolites, Antineoplastic; Cell Line, Tumor; Cell Membrane; Cytarabine; Drug Resistance, Neoplasm; Equilibrative Nucleoside Transporter 1; Glycine; Humans; Leukemia, T-Cell; Molecular Sequence Data; Point Mutation; Protein Structure, Tertiary; RNA, Messenger; Thioinosine

2009
Variability in transport and biotransformation of cytarabine is associated with its toxicity in peripheral blood mononuclear cells.
    Pharmacogenomics, 2011, Volume: 12, Issue:4

    Topics: Adult; Antimetabolites, Antineoplastic; Cell Survival; Cells, Cultured; Cytarabine; Cytidine Deaminase; Drug-Related Side Effects and Adverse Reactions; Equilibrative Nucleoside Transporter 1; Exons; Female; Genotype; Humans; Leukocytes, Mononuclear; Male; Middle Aged; Polymorphism, Genetic; Polymorphism, Single Nucleotide; Promoter Regions, Genetic; Risk Factors; Thioinosine; Young Adult

2011
Role of equilibrative nucleoside transporter 1 (ENT1) in the disposition of cytarabine in mice.
    Pharmacology research & perspectives, 2019, Volume: 7, Issue:6

    Topics: Animals; Antimetabolites, Antineoplastic; Cytarabine; Drug Interactions; Equilibrative Nucleoside Transporter 1; Female; Humans; Leukemia, Myeloid, Acute; Liver-Specific Organic Anion Transporter 1; Mice; Mice, Knockout; Organic Cation Transport Proteins; Symporters; Thioinosine

2019