Compounds > cytarabine

cytarabine and quizartinib

cytarabine has been researched along with quizartinib in 7 studies

Research

Studies (7)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's3 (42.86)24.3611
2020's4 (57.14)2.80

Authors

AuthorsStudies
Delabesse, E; Hospital, MA; Larrue, C; Manenti, S; Mansat-De Mas, V; Récher, C; Saland, E; Sarry, JE; Serhan, N; Tamburini, J; Vergez, F1
An, X; Cai, J; Huang, L; Li, QX; Liu, J; Wang, D; Wang, N; Wery, JP; Zhang, L; Zhou, D; Zhou, J1
He, R; Li, J; Liu, X; Pan, R; Wang, C1
Boswell, HS; Calin, GA; Chen, F; Gilca, M; Griffin, S; Guo, B; Konig, H; Niculite, C; Petrusca, D; Rice, S; Rogozea, A; Wu, X1
Den Haese, J; Elmeliegy, M; Jusko, WJ; Talati, C; Wetzler, M1
Alvarado, Y; Andreeff, M; Borthakur, G; Cortes, JE; Daver, N; DiNardo, CD; Estrov, Z; Ferrajoli, A; Garcia-Manero, G; Guerra, V; Jabbour, EJ; Jain, N; Kadia, T; Kantarjian, HM; Konopleva, M; Levis, M; Ohanian, M; Pemmaraju, N; Pierce, S; Pinsoy, MR; Ravandi, F; Swaminathan, M; Wierda, WG; Xiao, L1
Ariti, C; Burnett, AK; Clark, RE; Copland, M; Dennis, M; Gilkes, A; Hemmaway, C; Hills, RK; Knapper, S; Mehta, P; Radia, R; Russell, N; Thomas, IF; Upton, L1

Trials

2 trial(s) available for cytarabine and quizartinib

ArticleYear
A phase I/II study of the combination of quizartinib with azacitidine or low-dose cytarabine for the treatment of patients with acute myeloid leukemia and myelodysplastic syndrome.
    Haematologica, 2021, 08-01, Volume: 106, Issue:8

    Topics: Azacitidine; Benzothiazoles; Cytarabine; fms-Like Tyrosine Kinase 3; Humans; Leukemia, Myeloid, Acute; Middle Aged; Mutation; Myelodysplastic Syndromes; Phenylurea Compounds

2021
Randomized evaluation of quizartinib and low-dose ara-C vs low-dose ara-C in older acute myeloid leukemia patients.
    Blood advances, 2021, 12-28, Volume: 5, Issue:24

    Topics: Aged; Benzothiazoles; Cytarabine; Humans; Leukemia, Myeloid, Acute; Phenylurea Compounds

2021

Other Studies

5 other study(ies) available for cytarabine and quizartinib

ArticleYear
Antileukemic Activity of 2-Deoxy-d-Glucose through Inhibition of N-Linked Glycosylation in Acute Myeloid Leukemia with FLT3-ITD or c-KIT Mutations.
    Molecular cancer therapeutics, 2015, Volume: 14, Issue:10

    Topics: Animals; Antineoplastic Agents; Apoptosis; Benzothiazoles; Biphenyl Compounds; Cell Line, Tumor; Cell Proliferation; Cell Survival; Cytarabine; Deoxyglucose; Drug Resistance, Neoplasm; fms-Like Tyrosine Kinase 3; Glycolysis; Glycosylation; Humans; Leukemia, Myeloid, Acute; Mice, Inbred NOD; Mice, SCID; Mutation; Myeloid Cell Leukemia Sequence 1 Protein; Nitrophenols; Phenylurea Compounds; Piperazines; Protein Processing, Post-Translational; Proto-Oncogene Proteins c-kit; Signal Transduction; Sulfonamides; Xenograft Model Antitumor Assays

2015
AC220 and AraC cause differential inhibitory dynamics in patient-derived M5-AML with FLT3-ITD and, thus, ultimately distinct therapeutic outcomes.
    Experimental hematology, 2017, Volume: 45

    Topics: Aged; Animals; Antimetabolites, Antineoplastic; Benzothiazoles; Cytarabine; Disease Models, Animal; DNA Mutational Analysis; fms-Like Tyrosine Kinase 3; Gene Duplication; Genotype; Humans; Immunophenotyping; Leukemia, Myeloid, Acute; Male; Mice; Mice, Inbred NOD; Mice, SCID; Phenotype; Phenylurea Compounds; Protein Kinase Inhibitors; Tandem Repeat Sequences; Treatment Outcome; Tumor Burden; Xenograft Model Antitumor Assays

2017
Prenylation-dependent Ras inhibition by pamidronate inhibits pediatric acute myeloid leukemia stem and differentiated cell growth and survival.
    Biochemical and biophysical research communications, 2019, 09-24, Volume: 517, Issue:3

    Topics: Anilides; Annexin A5; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Apoptosis; Benzothiazoles; Bone Density Conservation Agents; Cell Differentiation; Cell Line, Tumor; Cell Proliferation; Child; Cytarabine; Daunorubicin; Drug Repositioning; Humans; Leukemia, Myeloid, Acute; Neoplastic Stem Cells; Pamidronate; Phenylurea Compounds; Primary Cell Culture; Protein Prenylation; Protein Processing, Post-Translational; Pyridines; ras Proteins

2019
Classic and targeted anti-leukaemic agents interfere with the cholesterol biogenesis metagene in acute myeloid leukaemia: Therapeutic implications.
    Journal of cellular and molecular medicine, 2020, Volume: 24, Issue:13

    Topics: Adult; Aged; Aged, 80 and over; Apoptosis; Benzothiazoles; Biosynthetic Pathways; Cell Line, Tumor; Cell Proliferation; Cholesterol; Cytarabine; Down-Regulation; Female; Gene Expression Regulation, Leukemic; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Intracellular Space; Leukemia, Myeloid, Acute; Male; Middle Aged; Phenylurea Compounds; Rosuvastatin Calcium; Translational Research, Biomedical; Young Adult

2020
Towards better combination regimens of cytarabine and FLT3 inhibitors in acute myeloid leukemia.
    Cancer chemotherapy and pharmacology, 2020, Volume: 86, Issue:3

    Topics: Antineoplastic Combined Chemotherapy Protocols; Apoptosis; Benzothiazoles; Biomarkers, Tumor; Cell Cycle; Cell Movement; Cell Proliferation; Cytarabine; fms-Like Tyrosine Kinase 3; Gene Expression Regulation, Neoplastic; Humans; Leukemia, Myeloid, Acute; Mutation; Phenylurea Compounds; Prognosis; Survival Rate; Tumor Cells, Cultured

2020