cytarabine has been researched along with oligonucleotides in 14 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 3 (21.43) | 18.7374 |
| 1990's | 5 (35.71) | 18.2507 |
| 2000's | 3 (21.43) | 29.6817 |
| 2010's | 3 (21.43) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Brach, MA; Herrmann, F; Kufe, DW | 1 |
| van Boom, JH; van der Marel, GA; Wang, AH; Zhang, H | 1 |
| Chen, YC; Lin, MT; Liu, MC; Lui, LT; Tang, JL; Wang, CH | 1 |
| Altona, C; de Vroom, E; Kaptein, R; Koning, TM; Pieters, JM; van Boom, JH; van der Marel, GA | 1 |
| Declève, A; Kaplan, HS; Lonai, P | 1 |
| Nagyvary, J; Pollard, DR | 1 |
| Kerr, IM; Rice, AP; Roberts, WK | 1 |
| Schwartz, HE; Ulfelder, KJ | 1 |
| Cheng, YC; Chou, KM; Kukhanova, M | 1 |
| Kiechle, FL; Zhang, X | 1 |
| Altman, JK; Andreeff, M; Borthakur, G; Brandwein, J; Carter, BZ; Estey, EH; Hedley, DW; Jacob, C; Jolivet, J; Karp, JE; Kassis, J; LaCasse, E; Mak, DH; Morris, SJ; Schiller, GJ; Schimmer, AD; Tallman, MS; Xu, W | 1 |
| Andreeff, M; Borthakur, G; Byrd, AL; Carter, BZ; Estey, E; Kantarjian, H; Konopleva, M; Mak, DH; Morris, SJ | 1 |
| Baer, MR; Ball, ED; Borthakur, G; Cortes, J; Dipersio, J; Fernandez, HF; Goodman, M; Kantarjian, H; Kolitz, JE; Wetzler, M | 1 |
| Andre, V; Andreeff, M; Brandt, JT; Callies, S; Erba, HP; Juckett, M; Kadam, S; Lahn, M; Sayar, H; Schmidt, S; Van Bockstaele, D | 1 |
4 trial(s) available for cytarabine and oligonucleotides
| Article | Year |
|---|---|
Phase I/II trial of AEG35156 X-linked inhibitor of apoptosis protein antisense oligonucleotide combined with idarubicin and cytarabine in patients with relapsed or primary refractory acute myeloid leukemia.
Topics: Acute Disease; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Cytarabine; Dose-Response Relationship, Drug; Drug Resistance, Neoplasm; Female; Gene Expression Regulation, Neoplastic; Humans; Idarubicin; Leukemia, Myeloid; Male; Middle Aged; Oligonucleotides; Peripheral Nervous System Diseases; Recurrence; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Treatment Outcome; X-Linked Inhibitor of Apoptosis Protein | 2009 |
XIAP antisense oligonucleotide (AEG35156) achieves target knockdown and induces apoptosis preferentially in CD34+38- cells in a phase 1/2 study of patients with relapsed/refractory AML.
Topics: Aged; Antigens, CD; Antimetabolites, Antineoplastic; Antineoplastic Combined Chemotherapy Protocols; Apoptosis; Caspases; Cytarabine; Drug Administration Schedule; Drug Dosage Calculations; Female; Gene Expression; Humans; Idarubicin; Leukemia, Myeloid, Acute; Male; Middle Aged; Myeloid Progenitor Cells; Oligonucleotides; Recurrence; RNA, Messenger; X-Linked Inhibitor of Apoptosis Protein | 2011 |
Phase 2 randomized study of p53 antisense oligonucleotide (cenersen) plus idarubicin with or without cytarabine in refractory and relapsed acute myeloid leukemia.
Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Cytarabine; Female; Genes, p53; Humans; Idarubicin; Leukemia, Myeloid, Acute; Male; Middle Aged; Oligonucleotides; Oligonucleotides, Antisense; Recurrence; Treatment Failure | 2012 |
Safety and pharmacokinetics of the antisense oligonucleotide (ASO) LY2181308 as a single-agent or in combination with idarubicin and cytarabine in patients with refractory or relapsed acute myeloid leukemia (AML).
Topics: Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Cytarabine; Demography; Female; Humans; Idarubicin; Inhibitor of Apoptosis Proteins; Leukemia, Myeloid, Acute; Male; Middle Aged; Oligonucleotides; Oligonucleotides, Antisense; Recurrence; Survivin; Treatment Outcome | 2013 |
10 other study(ies) available for cytarabine and oligonucleotides
| Article | Year |
|---|---|
Activation of the AP-1 transcription factor by arabinofuranosylcytosine in myeloid leukemia cells.
Topics: Base Sequence; Cytarabine; Enhancer Elements, Genetic; Gene Expression Regulation; Humans; Leukemia, Myeloid; Microbial Collagenase; Molecular Sequence Data; Oligonucleotides; Promoter Regions, Genetic; Proto-Oncogene Proteins c-jun; Regulatory Sequences, Nucleic Acid; Transcription, Genetic; Tumor Cells, Cultured | 1992 |
Conformational perturbation of the anticancer nucleotide arabinosylcytosine on Z-DNA: molecular structure of (araC-dG)3 at 1.3 A resolution.
Topics: Base Sequence; Cytarabine; DNA; Molecular Sequence Data; Molecular Structure; Nucleic Acid Conformation; Oligonucleotides | 1992 |
Successful reinduction of remission with low-dose Ara-C in a patient with myelodysplastic syndrome relapsed after allogeneic bone marrow transplantation: restoration of donor hematopoiesis detected by amplification of minisatellite genes.
Topics: Adult; Anemia, Refractory, with Excess of Blasts; Base Sequence; Bone Marrow Transplantation; Cytarabine; DNA Fingerprinting; Female; Genes, ras; Hematopoiesis; Humans; Molecular Sequence Data; Oligonucleotides; Polymerase Chain Reaction | 1992 |
Hairpin structures in DNA containing arabinofuranosylcytosine. A combination of nuclear magnetic resonance and molecular dynamics.
Topics: Base Sequence; Cytarabine; DNA; Magnetic Resonance Spectroscopy; Models, Chemical; Molecular Sequence Data; Molecular Structure; Nucleic Acid Conformation; Oligonucleotides; Phosphorus; Protons | 1990 |
Spontaneous induction of endogenous murine leukemia virus-related antigen expression during short-term in vitro incubation of mouse lymphocytes.
Topics: Animals; Antigens, Viral; Cells, Cultured; Cycloheximide; Cytarabine; Dactinomycin; Fluorescent Antibody Technique; Hybridization, Genetic; Leukemia Virus, Murine; Lymph Nodes; Lymphocytes; Mice; Mice, Inbred Strains; Mitomycins; Oligonucleotides; Spleen; Thymus Gland; Time Factors | 1974 |
Inhibition of pancreatic ribonuclease A by arabinonucleotides.
Topics: Animals; Arabinose; Cattle; Chromatography, Paper; Cytarabine; Cytidine; Cytosine Nucleotides; Kinetics; Nucleosides; Nucleotides; Oligonucleotides; Pancreas; Phosphoric Acids; Photometry; Ribonucleases; Ribose; Spectrophotometry, Ultraviolet; Structure-Activity Relationship; Uracil Nucleotides; Uridine | 1973 |
2-5A accumulates to high levels in interferon-treated, vaccinia virus-infected cells in the absence of any inhibition of virus replication.
Topics: Adenine Nucleotides; Animals; Cell Line; Cycloheximide; Cytarabine; Endoribonucleases; Haplorhini; HeLa Cells; Humans; Interferon Type I; Mice; Oligonucleotides; Oligoribonucleotides; Protein Biosynthesis; RNA, Double-Stranded; RNA, Ribosomal; RNA, Viral; Transcription, Genetic; Vaccinia virus; Viral Proteins; Virus Replication | 1984 |
Analysis of bases, nucleosides, and (oligo)nucleotides by capillary electrophoresis.
Topics: Capillary Action; Cytarabine; DNA; Drug Monitoring; Electrophoresis; Humans; Leukemia; Lymphocytes; Nucleosides; Nucleotides; Oligonucleotides; Purines; Pyrimidines; Reproducibility of Results; Sensitivity and Specificity; Spectrophotometry, Ultraviolet | 1996 |
A novel action of human apurinic/apyrimidinic endonuclease: excision of L-configuration deoxyribonucleoside analogs from the 3' termini of DNA.
Topics: Anions; Antineoplastic Agents; Antiviral Agents; Blotting, Western; Carbon-Oxygen Lyases; Cations; Chromatography, Agarose; Chromatography, Ion Exchange; Cytarabine; Cytosine; Deoxycytidine; Deoxycytidine Monophosphate; Deoxyribonuclease IV (Phage T4-Induced); Dioxolanes; DNA; DNA-(Apurinic or Apyrimidinic Site) Lyase; Electrophoresis, Polyacrylamide Gel; Endonucleases; Humans; Oligonucleotides; Recombinant Proteins; Reverse Transcriptase Inhibitors; Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization; Stereoisomerism; Thionucleosides; Tumor Cells, Cultured; Zalcitabine | 2000 |
Cytosine arabinoside substitution decreases transcription factor-DNA binding element complex formation.
Topics: Binding Sites; CCAAT-Enhancer-Binding Proteins; Cell Line, Tumor; Cytarabine; Cytosine; DNA-Binding Proteins; DNA, Neoplasm; HL-60 Cells; Humans; Macromolecular Substances; Oligonucleotides; Protein Binding; TATA-Box Binding Protein; Transcription Factor AP-2; Transcription Factors | 2004 |