cytarabine and lovastatin

cytarabine has been researched along with lovastatin in 11 studies

Research

Studies (11)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's6 (54.55)29.6817
2010's5 (45.45)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Benz, RD; Contrera, JF; Kruhlak, NL; Matthews, EJ; Weaver, JL1
Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A1
Chen, M; Fang, H; Liu, Z; Shi, Q; Tong, W; Vijay, V1
Ambroso, JL; Ayrton, AD; Baines, IA; Bloomer, JC; Chen, L; Clarke, SE; Ellens, HM; Harrell, AW; Lovatt, CA; Reese, MJ; Sakatis, MZ; Taylor, MA; Yang, EY1
Afshari, CA; Chen, Y; Dunn, RT; Hamadeh, HK; Kalanzi, J; Kalyanaraman, N; Morgan, RE; van Staden, CJ1
Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K1
Doroshenko, N; Doroshenko, P; Sabanov, V1
Hohl, RJ; Holstein, SA1
Braess, J; Hiddemann, W1
Appelbaum, FR; Banker, DE; Li, HY; Willman, CL; Zager, RA1
Appelbaum, FR; Banker, DE; Li, HY; Mayer, SJ; Willman, CL; Zager, RA1

Reviews

1 review(s) available for cytarabine and lovastatin

ArticleYear
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
    Drug discovery today, 2016, Volume: 21, Issue:4

    Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk

2016

Other Studies

10 other study(ies) available for cytarabine and lovastatin

ArticleYear
Assessment of the health effects of chemicals in humans: II. Construction of an adverse effects database for QSAR modeling.
    Current drug discovery technologies, 2004, Volume: 1, Issue:4

    Topics: Adverse Drug Reaction Reporting Systems; Artificial Intelligence; Computers; Databases, Factual; Drug Prescriptions; Drug-Related Side Effects and Adverse Reactions; Endpoint Determination; Models, Molecular; Quantitative Structure-Activity Relationship; Software; United States; United States Food and Drug Administration

2004
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
    Chemical research in toxicology, 2010, Volume: 23, Issue:1

    Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship

2010
FDA-approved drug labeling for the study of drug-induced liver injury.
    Drug discovery today, 2011, Volume: 16, Issue:15-16

    Topics: Animals; Benchmarking; Biomarkers, Pharmacological; Chemical and Drug Induced Liver Injury; Drug Design; Drug Labeling; Drug-Related Side Effects and Adverse Reactions; Humans; Pharmaceutical Preparations; Reproducibility of Results; United States; United States Food and Drug Administration

2011
Preclinical strategy to reduce clinical hepatotoxicity using in vitro bioactivation data for >200 compounds.
    Chemical research in toxicology, 2012, Oct-15, Volume: 25, Issue:10

    Topics: Chemical and Drug Induced Liver Injury; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Decision Trees; Drug Evaluation, Preclinical; Drug-Related Side Effects and Adverse Reactions; Glutathione; Humans; Liver; Pharmaceutical Preparations; Protein Binding

2012
A multifactorial approach to hepatobiliary transporter assessment enables improved therapeutic compound development.
    Toxicological sciences : an official journal of the Society of Toxicology, 2013, Volume: 136, Issue:1

    Topics: Animals; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Transport; Chemical and Drug Induced Liver Injury; Cluster Analysis; Drug-Related Side Effects and Adverse Reactions; Humans; Liver; Male; Multidrug Resistance-Associated Proteins; Pharmacokinetics; Rats; Rats, Sprague-Dawley; Recombinant Proteins; Risk Assessment; Risk Factors; Toxicity Tests

2013
Cell cycle-related changes in regulatory volume decrease and volume-sensitive chloride conductance in mouse fibroblasts.
    Journal of cellular physiology, 2001, Volume: 187, Issue:1

    Topics: Animals; Aphidicolin; Cell Cycle; Cell Division; Cell Line; Cell Size; Chlorides; Culture Media, Serum-Free; Cytarabine; Electric Conductivity; Enzyme Inhibitors; Fibroblasts; Hydroxyurea; Ion Transport; Lovastatin; Mice; Mimosine; Osmotic Pressure; Paclitaxel; Patch-Clamp Techniques

2001
Interaction of cytosine arabinoside and lovastatin in human leukemia cells.
    Leukemia research, 2001, Volume: 25, Issue:8

    Topics: Antineoplastic Combined Chemotherapy Protocols; Apoptosis; Cell Division; Cytarabine; Drug Synergism; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; K562 Cells; Lovastatin; MAP Kinase Signaling System; Mitogen-Activated Protein Kinases; Precursor Cell Lymphoblastic Leukemia-Lymphoma; ras Proteins

2001
The widening role of statins: RAS signal transduction and drug-induced cytotoxicity in human leukemia: a commentary to 'interaction of cytosine arabinoside and lovastatin in human leukemia cells'.
    Leukemia research, 2001, Volume: 25, Issue:8

    Topics: Antineoplastic Combined Chemotherapy Protocols; Cytarabine; Drug Synergism; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Leukemia; Lovastatin; ras Proteins

2001
Cholesterol-modulating agents kill acute myeloid leukemia cells and sensitize them to therapeutics by blocking adaptive cholesterol responses.
    Blood, 2003, May-01, Volume: 101, Issue:9

    Topics: Acute Disease; Antineoplastic Agents; Bone Marrow Cells; Bridged Bicyclo Compounds, Heterocyclic; Cholesterol; Cytarabine; Daunorubicin; Drug Synergism; HL-60 Cells; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Leukemia, Myeloid; Lipoproteins, LDL; Lovastatin; Membrane Lipids; Protein Prenylation; Protein Processing, Post-Translational; Radiation-Sensitizing Agents; Tricarboxylic Acids; Tumor Cells, Cultured

2003
Cholesterol synthesis and import contribute to protective cholesterol increments in acute myeloid leukemia cells.
    Blood, 2004, Sep-15, Volume: 104, Issue:6

    Topics: Biological Transport; Cholesterol, LDL; Coenzyme A Ligases; Cytarabine; Flow Cytometry; Humans; Hydroxymethylglutaryl-CoA Synthase; Leukemia, Myeloid, Acute; Lovastatin; Receptors, LDL; RNA, Messenger; Tumor Cells, Cultured

2004