cytarabine has been researched along with hydroxyurea in 554 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 369 (66.61) | 18.7374 |
| 1990's | 90 (16.25) | 18.2507 |
| 2000's | 63 (11.37) | 29.6817 |
| 2010's | 28 (5.05) | 24.3611 |
| 2020's | 4 (0.72) | 2.80 |
| Authors | Studies |
|---|---|
| Hansch, C; Khwaja, TA; Selassie, CD | 1 |
| Dias, CB; Hansch, C; Khwaja, TA; Pentecost, S; Selassie, CD | 1 |
| Benz, RD; Contrera, JF; Kruhlak, NL; Matthews, EJ; Weaver, JL | 1 |
| González-Díaz, H; Orallo, F; Quezada, E; Santana, L; Uriarte, E; Viña, D; Yáñez, M | 1 |
| Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A | 1 |
| García-Mera, X; González-Díaz, H; Prado-Prado, FJ | 1 |
| Chen, M; Fang, H; Liu, Z; Shi, Q; Tong, W; Vijay, V | 1 |
| Afshari, CA; Chen, Y; Dunn, RT; Hamadeh, HK; Kalanzi, J; Kalyanaraman, N; Morgan, RE; van Staden, CJ | 1 |
| Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K | 1 |
| Hernadi, F; Pinney, RJ; Smith, JT | 2 |
| Borsos, T; Ohanian, SH; Segerling, M | 1 |
| Cihak, A | 1 |
| Ross, DW | 2 |
| Grigg, GW; Sleigh, MJ | 1 |
| Lundgren, E; Roos, G | 1 |
| Kaidbey, KH | 1 |
| Dubbs, DR; Kit, S | 1 |
| Igarashi, T; Kishimoto, T; Okada, M; Yamamura, Y | 1 |
| Bossa, R; Galatulas, I; Leotta, L; Tofanetti, O | 1 |
| Barranco, SC; Gee, EL; Haenelt, BR | 1 |
| Honjo, T; Mizuno, D; Natori, S; Shimizu, A; Tsuda, M | 1 |
| Mathews, CK | 1 |
| Lotem, J; Sachs, L | 2 |
| Johnson, RT; Schor, SL; Waldren, CA | 1 |
| Brunk, CF; Yaffe, D | 1 |
| Bhuyan, BK; Day, KJ; Fraser, TJ | 1 |
| Azizkhan, JC; Goode, D; Speeg, KV; Stromberg, K | 1 |
| Carlson, MD; Spooner, BS | 1 |
| Asher, Y; Becker, Y | 1 |
| Aaronson, SA; Greenberger, JS | 1 |
| Reiter, RS; Solursh, M | 1 |
| Craig, R; Magnusson, G; Närkhammar, M; Reichard, P; Staub, M; Warner, H | 1 |
| Parks, WP; Scolnick, EM; Young, HA | 1 |
| Chang, S; Derger, JG; Hampar, B; Lenoir, G; Nonoyama, M | 1 |
| Coppey, J | 1 |
| Asher, Y; Becker, Y; Friedmann, A; Shlomai, J; Strauss, B | 1 |
| Wintersberger, E; Wintersberger, U | 1 |
| Pancheva, S | 1 |
| Marz, R; Plagemann, PG; Wohlhueter, RM | 1 |
| Burchiel, SW; Melmon, KL | 1 |
| Castellot, JJ; Miller, MR; Pardee, AB | 1 |
| Warrington, RC | 1 |
| Bailey, R; Bowden, L; Chaganti, R; Clarkson, B; Cunningham, I; Dowling, M; Gee, T; Hopfan, S; Knapper, W; Turnbull, A | 1 |
| Fleischer, J | 1 |
| Moran, RE; Straus, MJ | 2 |
| Mattern, J; Volm, M; Wayss, K | 1 |
| Brunner, KW; Carey, RW; Cuttner, J; DelDuca, V; Glidewell, OJ; Hoagland, HC; Holland, JF; Kung, FH; Silver, RT; Spurr, CL; Wiernik, PH | 1 |
| Ritter, EJ; Scott, WJ; Wilson, JG | 3 |
| Berkman, EM; Caplan, SN | 1 |
| Krieg, L; Mattern, J; Volm, M; Wayss, K | 1 |
| Harding, JW; Wright, JW | 1 |
| Duménil, D; Frindel, E; Sainteny, F | 1 |
| Necas, E; Neuwirt, J; Ponka, P | 1 |
| Kornacka, L; Malec, J; Sawecka, J | 1 |
| Alison, MR; Wright, NA | 1 |
| Ellem, KA; Mironescu, S | 1 |
| Gelderblom, H; Ozel, M; Wigand, R | 1 |
| Berger, NA; Weber, G | 1 |
| Bishop, J; Hallinan, FM; Lee, SH; Rozee, KR | 1 |
| Klem, EB | 1 |
| Bailyn, RS; Fleckman, P; Kaufman, S | 1 |
| Dumenil, D; Frindel, E; Guigon, M; Lepault, F; Sainteny, F | 1 |
| Gallwitz, D; Stahl, H | 1 |
| Adwankar, MK; Alate, AD; Amonkar, AJ; Khandalekar, DD; Sahasrabudhe, MB | 1 |
| Marsh, JC | 1 |
| Bases, R; Hsu, KC; Liebeskind, D; Mendez, F; Neubort, S | 1 |
| Brodsky, I; Conroy, JF; Fuscaldo, KE; Kahn, SB; Lamping, CG | 1 |
| Shimkin, MB; Stoner, GD; Theiss, JC | 1 |
| De Vries, A; Jerushalmy, Z; Payta, M; Pinkhas, J | 1 |
| Shimojo, H; Shiroki, K; Yamaguchi, K | 1 |
| Park, W; Phillips, I; Shephard, E; Stein, G; Stein, J | 1 |
| Hoffbrand, AV; Hooton, JW | 1 |
| Collins, AR | 1 |
| el Ashkar, A; Pazdernik, TL; Uyeki, EM | 1 |
| Green, CD; Tata, JR | 1 |
| Neĉas, E; Neuwirt, J | 1 |
| Flickinger, RA | 1 |
| Brincker, H | 1 |
| Burchenal, JH; Clarkson, BD; Cunningham, IB; Dowling, MD; Gee, TS | 1 |
| Hatanaka, M; Takano, T | 1 |
| Burchenal, J; D'angio, G; Exelby, P; Fang, S; Lieberman, P; Murphy, ML; Wollner, N | 1 |
| Leder, A; Leder, P; Orkin, S | 1 |
| Pelka, R; Sauer, H; Wilmanns, W | 1 |
| Haghbin, M | 1 |
| Baccarani, M; Bagnara, GP; Brunelli, MA; Gobbi, M; Ricci, P; Ruggero, D; Santucci, AM; Tura, S; Zaccaria, A | 1 |
| Kishimoto, T; Miyake, T; Nishizawa, Y; Watanabe, T; Yamamura, Y | 1 |
| Inoue, H; Kishimoto, T; Miyake, T; Nishizawa, Y; Watanabe, T | 1 |
| Boyse, EA; Goldstein, G; Hammerling, U; Storrie, B | 1 |
| Durie, BG; Salmon, SE | 1 |
| Kogoma, T; Lark, KG | 1 |
| Benedict, WF; Karon, M; Rucker, N | 1 |
| Phillips, FS; Sternberg, SS | 1 |
| Burchenal, JH; D'Angio, GJ; Exelby, PR; Lieberman, PH; Murphy, ML; Wollner, N | 1 |
| Berger, NA; Johnson, ES | 1 |
| Burchenal, JH; D'Angio, G; Exelby, P; Lieberman, PH; Murphy, ML; Wollner, N | 1 |
| Fischer, GA; Theiss, JC | 1 |
| Andrais, B; Mirzayans, R; Paterson, MC | 1 |
| Antoccia, A; Catena, C; Palitti, F; Raggi, T; Tanzarella, C | 1 |
| Desforges, JF; Fogaren, T; Miller, KB; Slapak, CA | 1 |
| Cen, D; Levin, J | 1 |
| Carter, GL; Cory, JG | 1 |
| Dawson, DA; Wilke, TS | 1 |
| Chan, TK; Chiu, E; Liang, R; Todd, D | 1 |
| Sasvári-Székely, M; Spasokukotskaja, T; Staub, M; Taljanidisz, J | 1 |
| Kamiguchi, H; Kawahara, T; Matsumoto, M; Ohkubo, T; Tsuda, M; Yamamura, M | 1 |
| Albain, KS; Erickson, LC; Fisher, RI; Fisher, SG; Stiff, PJ; Swinnen, LJ | 1 |
| Arentsen-Honders, MW; Colly, LP; Kester, MG; Richel, DJ; ter Riet, PM; Willemze, R | 1 |
| Lihou, MG; Smith, PJ; Tomlinson, FH | 1 |
| Gandhi, V; Keating, MJ; Kemena, A; Plunkett, W | 1 |
| Bauters, F; Casassus, P; Dine, G; Guilhot, F; Harousseau, JL; Ifrah, N; Lamagnère, JP; Rochant, H; Tanzer, J; Tilly, H | 1 |
| Collins, AR; Gedik, CM | 1 |
| Cheung, NK; Exelby, PR; Gulati, SC; Kushner, BH; Kwon, JH; O'Reilly, RJ | 1 |
| Bhalla, K; Grant, S; Swerdlow, P | 1 |
| Antoniw, P; Bagshawe, KD; Boden, JA; Boxer, GM; Patridge, TA; Pedley, RB; Sharma, K; Southall, PJ | 1 |
| Ellis, NK; Erickson, LC; Swinnen, LJ | 1 |
| David, JC; Marquet, J; Zittoun, J | 1 |
| Collins, A; Gedik, C; Macintyre, F | 1 |
| Ahmad, M; Brizard, A; Dreyfus, B; Guilhot, F; Huret, JL; Kitzis, A; Mahon, FX; Tanzer, J | 1 |
| Labanowska, J; Tolmach, LJ | 1 |
| Colinas, RJ; Condit, RC; Paoletti, E | 1 |
| Zaborowska, D; Zuk, J | 1 |
| Albain, KS; Erickson, LC; Fisher, RI; Stiff, PJ; Swinnen, LJ | 1 |
| Darroudi, F; Natarajan, AT; van der Schans, GP | 1 |
| Cassileth, PA | 1 |
| Blakey, DH; Douglas, GR | 1 |
| Cory, JG; Matsumoto, M; Rey, DA | 1 |
| Barone, JE; Barone, JG; DiGiacomo, JC; Snyder, AB | 1 |
| Galanello, R; Papayannopoulou, T; Stamatoyannopoulos, G; Veith, R | 2 |
| Dean, A; Fordis, CM; Ley, T; Schechter, AN; Wu, YJ | 1 |
| Platt, OS | 1 |
| Snyder, RD; Van Houten, B | 1 |
| DeSimone, J; Hall, L; Heller, P; Lavelle, D; Zwiers, D | 1 |
| Estey, E; Silberman, L; Zwelling, LA | 1 |
| Alexander, RB; Coffey, DS; Nelson, WG | 1 |
| Freireich, EJ; Gutterman, J; Kantarjian, HM; Keating, MJ; Kurzrock, R; McCredie, KB; Talpaz, M | 1 |
| Galanello, R; Papayannopoulou, T; Stamatoyannopoulos, G | 1 |
| Akiyama, Y; Kubota, M; Mikawa, H; Takimoto, T; Tanizawa, A | 1 |
| Pfeifer, GP; Steigerwald, SD | 1 |
| Cox, GS; Park, KH | 1 |
| Archimbaud, E; Fiere, D; Sebban, C | 1 |
| Dahlberg, WK; Little, JB; Ueno, AM | 1 |
| Chitnis, MP; Deshpande, SS; Satyamoorthy, K | 1 |
| Cortés, F; Mateos, S; Ortiz, T; Piñero, J | 2 |
| Andersson, HC; Kihlman, BA | 2 |
| Denizeau, F; Jutras, D; Marion, M | 1 |
| Anuszewska, E; Koziorowska, J | 1 |
| Maemori, M; Matsuda, Y; Tobari, I | 1 |
| Aller, P; Bernabeu, C; Cabañas, C; Mata, F; Rius, C | 1 |
| Akiyama, Y; Kiriyama, Y; Kitoh, T; Kubota, M; Mikawa, H; Takimoto, T; Tanizawa, A | 1 |
| Advani, SH; Das Gupta, A; Dole, MG; Giri, NK; Gopal, R; Kurkure, PA; Nair, CN; Pai, SK; Pai, VR; Saikia, TK | 1 |
| Heinemann, V; Plunkett, W | 1 |
| Carr, DS; Gonzalez, MF; Noble, TA | 1 |
| Aller, P; Hirschhorn, RR; Rius, C | 1 |
| Genter, EI; Mikhel'son, VM; Zhestianikov, VD | 1 |
| Cleaver, JE | 3 |
| Brizard, A; Desmarest, MC; Dreyfus, B; Giraud, C; Guilhot, F; Huret, JL; Tanzer, J | 1 |
| Walker, MM; Wanda, PE | 1 |
| Maemori, M; Matsuda, Y; Seki, N; Tobari, I | 1 |
| Johnson, RT; Mullinger, AM | 2 |
| Spath, A; Tempel, K | 1 |
| Biondi, A; D'Incalci, M; Giudici, G; Mannironi, C; Masera, G; Rossi, V; Ubezio, P | 1 |
| Bantle, JA; Courchesne, CL | 1 |
| Albain, KS; Barnes, DM; Erickson, LC; Fisher, RI; Fisher, SG; Swinnen, LJ | 1 |
| FitzGerald, GB; Ratliff, J; Wick, MM | 1 |
| Wawra, E | 1 |
| Cajelli, E; Ghia, M; Martelli, A | 1 |
| Collins, AR; Downes, CS; Johnson, RT; Mullinger, AM; Ord, MJ | 1 |
| Mullenders, LH; Natarajan, AT; van Kesteren-van Leeuwen, AC; van Zeeland, AA | 1 |
| Burhans, WC; Heintz, NH; Selegue, JE | 1 |
| Hittelman, WN | 1 |
| Bleyer, WA; Geyer, JR; Heideman, RL; Kosnik, EJ; Milstein, JM; Morris, JD; Mulne, AF; Pendergrass, TW; Ruymann, FB; Stuntz, JT | 1 |
| Jones, PA; Liu, L; Nyce, J | 1 |
| Oikawa, A; Tohda, H | 1 |
| Booker, R; Truman, JW | 1 |
| Collins, A | 2 |
| Fram, RJ; Robichaud, NJ | 1 |
| Collins, AR; Downes, CS; Elliott, GC; Johnson, RT; Mullinger, AM; Rasko, I; Squires, S | 1 |
| Durkacz, BW; Harris, AL; Moses, K | 1 |
| Chebotarev, AN; Golovina, ME; Smirnova, TD | 1 |
| Calissano, P; Coccia, EM; Di Luzio, A; Improta, T; Romeo, G; Salvatore, AM | 1 |
| Bigner, SH; Gockerman, JP; Sokal, JE | 1 |
| Al-Ansari, HM; Farkas, WR; Walden, TL | 1 |
| Helson, L; Kushner, BH | 1 |
| Simons, JW; van der Schans, GP; van Zeeland, AA; Westerveld, A; Zdzienicka, MZ | 1 |
| Fernandes, DJ; Neff, TA; Paff, MT; Smith-Nanni, C | 1 |
| Brunat-Mentigny, M; Chastagner, P; Czorny, A; Lapras, C; Olive, D; Philip, T; Zucker, JM | 1 |
| Nilsson, TK; Norberg, B | 1 |
| Hayashi, M; Honma, Y; Hozumi, M; Okabe-Kado, J | 1 |
| Bhandal, AK; Brelvi, ZS; Studzinski, GP | 1 |
| Brewer, G; Kobs, G; Peltz, SW; Ross, J | 1 |
| Ishiguro, T; Ochi, T; Ohsawa, M; Otsuka, F | 1 |
| Bantle, JA; Dawson, DA | 1 |
| Kapp, LN; Painter, RB; Young, BR | 1 |
| Collins, A; Oates, DJ | 1 |
| Enomoto, T; Hanaoka, F; Ohno, H; Ohsawa, M; Otsuka, F; Yamada, K; Yamada, M | 1 |
| Chao, CC; Ducore, JM; Rosenstein, BS | 1 |
| Ahnström, G | 1 |
| Bantle, JA; Courchesne, CL; Dawson, DA | 1 |
| Schilsky, RL; Ultmann, JE; Watson, S; Williams, SF | 1 |
| Haanen, C; Marie, JP; Marquet, J; Zittoun, J; Zittoun, R | 1 |
| Ben-Ishay, Z; Borenstein, A; Prindull, G; Sharon, S | 1 |
| Birgens, HS; Geisler, C; Hansen, NE; Hasselbalch, H | 1 |
| Bligham, G; Freireich, EJ; Gehan, E; Hester, JP; Kantarjian, HM; Keating, MJ; McCredie, KB; Smith, TL; Talpaz, M; Walters, RS | 1 |
| Ashman, CR; Davidson, RL; Kaufman, ER | 1 |
| Jehn, U; Löwenberg, B | 1 |
| Jehn, U; Löwenberg, B; Zittoun, R | 1 |
| Kimura, K; Tanaka, M; Yoshida, S | 1 |
| Ishikura, H; Izumi, Y; Mochizuki, T; Okazaki, T; Sawada, H; Tashima, M; Uchino, H | 1 |
| Fram, RJ; Kufe, DW | 3 |
| Ishiguro, T; Ochi, T; Ohsawa, M | 1 |
| Allavena, P; Bonner, WM; D'Incalci, M; Wu, RS | 1 |
| Chiu, ML; Irvin, JL | 1 |
| Gotlib, VIa; Pelevina, II; Taponaĭnen, NIa | 1 |
| Akerblom, L; Reichard, P | 1 |
| Bohn, T; Haas, R; Hunstein, W; Mundinger, A; Schaz, K | 1 |
| Malick, NC; Snyder, RD | 1 |
| Seidel, HJ | 1 |
| Benedict, WF; Karon, M | 1 |
| Greenwald, ES | 1 |
| Canellos, GP; Whang-Peng, J | 1 |
| Burchenal, JH; Carter, SK | 1 |
| Crissman, HA; Tobey, RA | 2 |
| Simmonds, WP | 1 |
| Clarkson, BD; Yataganas, X | 1 |
| Israel, L | 1 |
| Dantzig, PI | 1 |
| Falkson, G; Geddes, EW | 1 |
| Bohunicky, L; Cerny, V; Halko, J; Koza, I; Krizan, Z; Petrek, C; Poliakova, L | 1 |
| Alimena, G; Amadori, S; Esposito, A; Mandelli, F; Monarca, B; Papa, G | 1 |
| Pennington, TH | 1 |
| Alberti, A; Amadori, S; Baccarani, M; Basetta, E; Buonanno, G; Cacciola, E; Cajozzo, A; Carnevali, C; di Marco, P; Fioritoni, G; Leoni, F; Lucarelli, G; Magro, S; Mandelli, F; Monfardini, S; Musso, R; Panzacchi, G; Porcellini, A; Rizzoli, V; Rossi Ferrini, P; Salti, F; Torlontano, G; Tura, S | 1 |
| Cohen, LS; Studzinski, GP | 1 |
| Djordjevic, B; Kim, JH | 1 |
| Coleman, AW; Coleman, JR; Kankel, D; Werner, I | 1 |
| Jacobs, EM; Johnson, FD | 1 |
| Bell, E | 1 |
| Heidelberger, C; Huberman, E | 1 |
| Aasen, J; Haukenes, G | 1 |
| Adamson, DJ; Bowdon, BJ; Vail, MH; Wheeler, GP | 1 |
| Hawtrey, AO; Jones, PA; Taderera, JV | 1 |
| Conkie, D; Paul, J | 1 |
| Bhuyan, BK; Fraser, TJ | 2 |
| Bedford, JS; Bender, MA; Griggs, HG | 1 |
| Selawry, OS | 1 |
| Goldstein, DA; Hall, MR; Lerner, RA; Meinke, W | 1 |
| Mattoccia, LP; Roberti, S | 1 |
| Bitter-Suermann, D; Clauss, I; Falke, D | 1 |
| Crouch, NA; Rawls, WE; Tevethia, SS; Tompkins, WA | 1 |
| Rideau, C; Smulson, ME | 1 |
| Burroughs, MA; Derge, JG; Hampar, B; Martos, LM; Tagamets, MA | 1 |
| Sokol, F; Tan, KB | 1 |
| Karran, P | 1 |
| Derge, JG; Hampar, B; Showalter, SD | 1 |
| Honess, RW; Roizman, B | 1 |
| Garfinkle, B; McAuslan, BR | 1 |
| Girard, M; Manteuil, S | 1 |
| Chang, SY; Derge, JG; Hampar, B; Nonoyama, M; Showalter, SD; Tagamets, A | 1 |
| Glaser, R; Mele, J; Nonoyama, M; Rapp, F; Zimmerman, J | 1 |
| Becker, Y; Ben-Zeev, A; Weinberg, E | 1 |
| Tange, T | 1 |
| Alberts, DS; Golde, DW | 1 |
| Hawtrey, AO; Robertson, G; Scott-Burden, T | 1 |
| Bailey, I; Kiryabwire, Y; Magrath, IT; Mugerwa, J; Olweny, C | 1 |
| Gunz, FW; Levi, JA; Vincent, PC | 3 |
| Jungi, WF | 1 |
| Alberto, P; Brunner, KW; Martz, G; Nagel, G; Obrecht, JP; Senn, HJ | 1 |
| Dominick, CA; Dykes, DJ; Griswold, DP; Kelley, CA; Roberts, BJ | 1 |
| Gee, TS; Grabstald, H; Schreibman, SM | 1 |
| Burchenal, JH; Clarkson, BD; Haghbin, M; Miké, V; Murphy, ML; Tan, CC | 1 |
| Burchenal, JH; Clarkson, BD; Cunningham, B; Dowling, MD; Gee, TS; Haghbin, M; Tan, CT | 1 |
| Conroy, JF | 1 |
| Cunningham, DD; Remo, RA | 1 |
| Craig, N | 1 |
| Goldin, A | 1 |
| Carter, SK | 1 |
| Bases, R; Erlanger, B; Hsu, KC; Liebeskind, D | 1 |
| Andersson, J; Melchers, F | 1 |
| Brachet, J; De Schutter, A; Hanocq, F; Hubert, E | 1 |
| Adamson, RH; Hahn, MA | 1 |
| Banerjee, S; Kelleher, JK; Margulis, L; Winston, M; Younger, KB | 1 |
| Cikes, M; Klein, G | 1 |
| Abbott, J; Holtzer, H; Mayne, R | 1 |
| Homan, ER; Neil, GL | 1 |
| Bhuyan, BK; Fraser, TJ; Gray, LG; Kuentzel, SL; Neil, GL | 1 |
| Cooper, EH | 1 |
| Barranco, SC; Novak, JK | 1 |
| Brunner, KW | 1 |
| Creasey, WA; Sartorelli, AC | 1 |
| Benckhuijsen, C | 1 |
| Kovaleva, LG | 1 |
| Dano, K; Nissen, NI | 1 |
| Dales, S; Ichihashi, Y; Matsumoto, S | 1 |
| Chu, EH; Smith, DB | 1 |
| Bonder, RH; Van Scott, EJ | 2 |
| Stoughton, RB | 1 |
| Groth, DP; Horwitz, S; Vogler, WR | 1 |
| Arlett, CF | 1 |
| Inagaki, A; Nakamura, T; Wakisaka, G | 1 |
| Chae, CB; Irvin, JL; Krasny, H; Piantadosi, C; Williams, A | 1 |
| Farber, E; Landay, M; Lee, TN; Liang, H; Lieberman, MW; Starr, R; Verbin, RS | 1 |
| Brockman, RW; Lloyd, HH; Mellett, LB; Montgomery, JA; Schabel, FM; Skipper, HE; Wilkoff, LJ | 1 |
| Granoff, A; Kucera, LS | 1 |
| Djordjevic, B; Kim, JH; Perez, AG | 1 |
| Detke, S | 1 |
| Hittelman, WN; Sen, P | 1 |
| Meistrich, ML; Meyn, RE; White, RA | 1 |
| Anger, G; Fink, R; Höche, D | 1 |
| Cadman, E; Rauscher, F | 1 |
| Kolata, G | 1 |
| Jost, JP; Seldran, M; Wilks, A | 1 |
| Albert, DA; Bluestein, HG | 1 |
| Spiers, AS | 1 |
| Hurt, MM; Moses, RE | 1 |
| Kerrigan, D; Minford, J; Nichols, M; Shackney, S; Zwelling, LA | 1 |
| Burry, RW | 1 |
| Ritter, EJ | 1 |
| Klein, G; Moar, MH | 1 |
| Ghavimi, F; Miller, DR; Rosen, G; Steinherz, PG; Wang, Y; Wollner, N | 1 |
| Endo, H; Inokuchi, K; Masuda, H; Yamamoto, M | 1 |
| Lamon, EW; Lidin, BI | 1 |
| Bresnick, E; Eastman, A; Ireland, CM | 1 |
| Klinman, NR; Teale, JM | 1 |
| Dantas, M; Drebing, C; Glode, LM; Koeppler, H; Robinson, WA; Thomas, MR | 1 |
| Downes, CS | 1 |
| Collins, AR; Elliott, GC; Johnson, RT; Squires, S | 1 |
| Clarkson, JM; Mitchell, DL | 1 |
| Bradley, MO; Taylor, VI | 1 |
| Baumbach, LL; Marashi, F; Plumb, M; Stein, G; Stein, J | 1 |
| Lees, RK; MacDonald, HR | 1 |
| Bender, MA; Ishii, Y | 1 |
| Scott, JM; Weir, DG | 1 |
| Dardick, I; Dubsky, M; Kiss, G; Setterfield, G; Sheinin, R | 1 |
| Lee, SH; Sartorelli, AC | 1 |
| Costanzo, C; Kubota, K; Preisler, HD | 2 |
| Hittelman, WN; Pollard, M | 1 |
| Regan, JD; Snyder, RD; Van Houten, B | 1 |
| Hanaoka, F; Kato, H; Yamada, K; Yamada, M | 4 |
| Gotlib, VIa; Pelevina, II | 1 |
| Filatov, MV; Sheĭkna, TA | 1 |
| Chang, LM; Yew, FH | 1 |
| Amar, M; Bernard, JF; Brousse, N; Chastang, C; Desaint, B; Herrera, A; Mancilla, F; Renoux, M; Solal-Celigny, P; Vroclans, M | 1 |
| Kufe, DW; Luisi-DeLuca, C; Mitchell, T; Spriggs, D | 1 |
| Baker, LH; Balcerzak, SP; Chen, TT; Coltman, CA; Hester, JP; Morrison, FS; Stephens, RL; Waddell, CC | 1 |
| Howell, SB; Pfeifle, CE | 1 |
| Chertkov, IL; Drize, NI | 1 |
| Blakely, WF; Joner, EI; Ward, JF | 1 |
| Alison, MR; Benton, HP | 1 |
| Filatov, MV; Sheĭkina, TA | 1 |
| Collins, AR; Downes, CS; Johnson, RT | 1 |
| Fischer, P; Haas, O; Paietta, E; Schwarzmeier, JD | 1 |
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| Krykowski, E; Mazurowa, A; Olszańska-Skorek, T; Polkowska-Kulesza, E; Płuzańska, A; Robak, T | 1 |
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| Clarkson, BD; Gee, TS; Mertelsmann, R; Miké, V; Passe, S | 1 |
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| Dräger, AM; Huijgens, PC; Schuurhuis, GJ; Teule, GJ; van Leeuwen-Stok, AE; Visser-Platier, AW | 1 |
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| Hasenclever, D; Loeffler, M; Tsodikov, A | 1 |
| Ashmore, J; Galgut, P; Henderson, B; Nair, S; Olsen, I; Patel, M; White, PA; Wilson, M | 1 |
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| Cole, KJ; Grover, PL; Martin, FL; Phillips, DH; Weaver, G | 1 |
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| Kaya, H; Maeno, K; Matsuda, T; Nakamura, S; Ohtake, S; Okafuji, K; Tanaka, N; Terasaki, Y | 1 |
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| Akita, S; Akiyama, M; Anderson, KC; Eto, Y; Kanda, N; Kawano, T; Mizoguchi, H; Ohno, T; Yamada, H; Yamada, O | 1 |
| Herrera, P; Jodra, MH; Laraña, JG; López, J; Navarro, JL; Odriozola, J; Pérez de Oteyza, J; Ramos, ML; Ramos, P; Roldán, E; Villalón, L; Zamora, C | 1 |
| Kelly, S; Nguyen, M; Sun, D; Urrabaz, R; Weitman, S | 1 |
| Ault, P; Cortes, J; Kaled, ES; Kantarjian, H; Koller, C | 1 |
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| Hentrich, M; Ledderose, G; Salat, C; Stoetzer, OJ | 1 |
| Hentrich, M; Salat, C; Stoetzer, OJ | 1 |
| Abbrederis, K; Apfelbeck, U; Baldinger, C; Buder, R; Burgstaller, S; Duba, C; Eisterer, W; Fiegl, M; Fridrik, M; Gastl, G; Geissler, D; Greil, R; Hausmaninger, H; Hilbe, W; Köck, L; Krieger, O; Kühr, T; Lang, A; Lin, W; Linkesch, W; Lutz, D; Michlmayr, G; Pont, J; Seewann, H; Thaler, J; Zabernigg, A | 1 |
| Abgrall, JF; Berthou, C; Braekeleer, MD; Bris, MJ; Calvez, GL; Herry, A; Marion, V; Morel, F | 1 |
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| Bianchi, N; Borgatti, M; Fibach, E; Gambari, R; Lampronti, I; Prus, E | 1 |
| Allsop, D; El-Agnaf, OM; Hewitt, R; Martin, FL; Paleologou, KE; Williamson, SJ | 1 |
| Chagnon, MC; Lhuguenot, JC; Padieu, M; Severin, I | 1 |
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| Kimura, S; Kuroda, J; Maekawa, T; Nogawa, M; Ottmann, OG; Sato, K; Segawa, H; Yuasa, T | 1 |
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| Cho, SH; Crain, C; Fujii, GH; Parry, D; Toouli, CD | 1 |
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| Abramsson-Zetterberg, L; Alexander, J; Husøy, T; Paulsen, JE; Ølstørn, HB | 1 |
| Cedrone, M; Chierichini, A; Diverio, D; Foà, R; Lo Coco, F; Mariani, G; Pasquini, L; Pelosi, E; Peschle, C; Riccioni, R; Rossini, A; Saulle, E; Testa, U; Vitale, A | 1 |
| Chan, GW; Miller, KB; Winer, ES | 1 |
| Bousquet, M; Brousset, P; Dastugue, N; De Mas, V; Delsol, G; Duchayne, E; Laurent, G; Quelen, C; Roquefeuil, B | 1 |
| Brychtova, Y; Buchtova, I; Doubek, M; Mayer, J; Palasek, I | 1 |
| Hori, H; Kawai, Y; Ueda, T; Yoshio, N | 1 |
| Fay, M; Goldman, J; Murphy, PT; O'Donnell, R; Quinn, J; Swords, R | 1 |
| Irving, I; Kennedy, GA; McCarthy, C; Perel, JM; Walker, O; Williams, B | 1 |
| Alimena, G; Bongarzoni, V; Borza, PA; Breccia, M; Carmosino, I; D'Andrea, M; D'Elia, GM; Latagliata, R; Mandelli, F; Mecarocci, S; Mengarelli, A; Morano, SG; Petti, MC | 1 |
| Bouabdallah, K; Daskalakis, M; Johansson, B; Kunzmann, R; Lübbert, M; Mauritzson, N; Müller-Berndorff, H; Onida, F; Schmitt-Gräff, A | 1 |
| Owen-Lynch, PJ; Pierce, A; Thompson, SE; Underhill-Day, N; Whetton, AD; Xenaki, D | 1 |
| Aguilera Cros, C; Gómez, JP; Gutierrez, I | 1 |
| Antonenko, EV; Cherepovich, VS; Grinëv, VV; Lotkova, ES; Shakhlevich, EV | 1 |
| Fujita, H; Kurata, M; Maeda, A; Matsushita, A; Mori, M; Nagai, K; Nagai, Y; Takahashi, T; Tanaka, K; Tanaka, Y; Togami, K | 1 |
| Barbany, G; Bengtsson, M; Göransson, H; Hagberg, A; Höglund, M; Isaksson, A; Olsson-Strömberg, U; Simonsson, B; Wickenberg-Bolin, U | 1 |
| Burnett, AK; Goldstone, AH; Hills, RK; McMullin, MF; Milligan, D; Prentice, AG; Wheatley, K | 1 |
| Güerci, A; Liviac, D; Marcos, R | 1 |
| Camitta, B; Dubowy, R; Graham, M; Hakami, N; Kletzel, M; Mahoney, D; Newman, E; Ravindranath, Y | 1 |
| Czyz, M; Jakubowska, J; Stasiak, M; Sztiller-Sikorska, M; Wozniak, M | 1 |
| Chen, ZC; Li, L; Li, QB; Xia, LH; You, Y; Zou, P | 1 |
| Capobianchi, A; Capria, S; Cardarelli, L; Foà, R; Gentile, G; Gianfelici, V; Martino, P; Meloni, G; Trisolini, SM | 1 |
| Alam, F; Chin, KJ | 1 |
| Fousteri, MI; Giglia-Mari, A; Gourdin, AM; Houtsmuller, AB; Kool, H; Mullenders, LH; Overmeer, RM; Siegal, G; Vermeulen, W | 1 |
| Barbagallo, I; Chiarenza, A; Conticello, C; Del Fabro, V; Di Raimondo, F; Giallongo, C; La Cava, P; Palumbo, GA; Parrinello, N; Romano, A; Stagno, F; Tibullo, D | 1 |
| Ayemou, R; Koffi, KG; Kouakou, B; Méité, N; Nanho, DC; Ndiaye, FS; Sanogo, I; Sawadogo, GD; Sékongo, YM; Tolo-Diebkilé, A | 1 |
| Chung, I; Eastman, A; Garner, KM; Montano, R; Parry, D | 1 |
| Atkinson, HD; Colovic, M; Colovic, N; Jankovic, G; Kraguljac, N; Radojkovic, M; Stanisavljevic, D; Suvajdzic, N; Tomin, D; Vidovic, A | 1 |
| de la Torre, C; Pincheira, J; Rodríguez, N; Valenzuela, CY | 1 |
| Prada Garcia, C; Rodriguez Prieto, MÁ; Sanchez Sambucety, P | 1 |
| Chen, H; Chen, J; Du, G; Han, Q; Liu, C; Sun, M; Wang, W; Wu, L | 1 |
| Amadori, S; de Witte, T; Halkes, CJ; Karrasch, M; Marie, JP; Meert, L; Meloni, G; Muus, P; Rapion, J; Suciu, S; Vignetti, M; Willemze, R | 1 |
| Iland, HJ; Seymour, JF; Wei, A | 1 |
| Ahn, C; Choi, Y; Hong, EJ; Jeung, EB; Kang, HY; Yang, H | 1 |
| Balleari, E; Bernal, T; Beyne-Rauzy, O; Bordessoule, D; Calabuig, M; Cametti, G; Campelo, MD; Cheze, S; Cony-Makhoul, P; Dreyfus, F; Fenaux, P; Fensterl, J; Ferrero, D; Gaidano, G; Germing, U; Gioia, D; Götze, K; Guerci-Bresler, A; Hamel, JF; Kaivers, J; Kelaidi, C; Komrokji, R; Kotsianidis, I; Müller-Thomas, C; Pane, F; Park, S; Ramos, F; Roboz, GJ; Rose, C; Sanna, A; Santini, V; Sanz, GF; Sapena, R; Sekeres, MA; Stamatoullas, A; Steensma, DP; Thépot, S; Toma, A; Vey, N; Wattel, E | 1 |
| Ahn, C; Hong, EJ; Jeung, EB; Kang, HS; Kang, HY | 1 |
| Guo, J; Parasramka, S; Rosenfeld, M; Talari, G; Villano, JL | 1 |
| Moyo, TK; Savona, MR | 1 |
| Bertolini, F; Cassisa, A; Gasparin, P; Miggiano, MC | 1 |
| Almakadi, M; Aslostovar, L; Bhatia, M; Boyd, AL; Collins, TJ; Foley, R; Julian, JA; Kim, RB; Leber, B; Leong, DP; Levine, MN; Tirona, RG; Xenocostas, A | 1 |
| Bérard, E; Bertoli, S; Delabesse, E; Huguet, F; Picard, M; Récher, C; Sarry, A; Tavitian, S; Vergez, F | 1 |
| Assaraf, YG; Berman, B; Levin, M; Stark, M | 1 |
| Jin, L; Li, Y; Liu, X; Lu, L; Qu, J; Xiao, M; Xu, L; Yin, Z | 1 |
| Bruserud, Ø; Fredly, HK; Gjertsen, BT; Grønningsæter, IS; Hatfield, KJ | 1 |
| Antunovic, P; Cammenga, J; Deneberg, S; Derolf, ÅR; Eriksson, A; Höglund, M; Juliusson, G; Lazarevic, V; Lehmann, S; Lorenz, F; Möllgård, L; Ölander, E; Österroos, A; Uggla, B; Wennström, L | 1 |
| Diao, S; DiNardo, C; DiPippo, AJ; Konopleva, M; Maiti, A; Nichols, ED; Ning, J; Qiao, W | 1 |
| Fischer, AS; Kersh, AE; Rosenbach, M; Shields, BE; Torre, EA; Xu, X | 1 |
| Borthakur, G; Brandt, M; Daver, N; DiNardo, CD; Garcia-Manero, G; Jabbour, E; Jain, N; Kadia, TM; Kantarjian, H; Kim, K; Konopleva, M; Loghavi, S; Pemmaraju, N; Pierce, S; Rausch, CR; Ravandi, F; Sasaki, K; Short, NJ; Tang, G; Yilmaz, M | 1 |
38 review(s) available for cytarabine and hydroxyurea
| Article | Year |
|---|---|
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk | 2016 |
Digital abnormalities in monkeys and rats.
Topics: Abnormalities, Drug-Induced; Acetazolamide; Animals; Cell Division; Cell Survival; Cytarabine; DNA; Ectoderm; Extremities; Fingers; Haplorhini; Hydroxyurea; Macaca; Macaca mulatta; Mesoderm; Rats; Time Factors; Toes | 1977 |
The effects of cancer chemotherapeutic agents on normal hematopoietic precursor cells: a review.
Topics: Alkylating Agents; Animals; Antibiotics, Antineoplastic; Antimetabolites, Antineoplastic; Antineoplastic Agents; Asparaginase; Benzamides; Busulfan; Carmustine; Cisplatin; Cyclophosphamide; Cytarabine; Drug Evaluation, Preclinical; Erythrocytes; Fluorouracil; Hematopoietic Stem Cells; Humans; Hydroxyurea; Lomustine; Methotrexate; Nitrogen Mustard Compounds; Spleen; Vinca Alkaloids | 1976 |
The use of metabolic inhibitors in the analysis of eukaryotic DNA repair.
Topics: Animals; Antimetabolites; Cytarabine; DNA Damage; DNA Repair; HeLa Cells; Humans; Hydroxyurea; Ultraviolet Rays | 1990 |
Augmentation of hemoglobin synthesis by S-phase specific drugs in the K562 cell line.
Topics: Adult; Azacitidine; Cell Line; Cytarabine; Deoxyribonuclease HpaII; DNA Restriction Enzymes; Fetal Hemoglobin; Globins; Hemoglobinopathies; Humans; Hydroxyurea; Interphase; Kinetics; Transcription, Genetic | 1985 |
Intercalator-induced, topoisomerase II-mediated DNA cleavage and its modification by antineoplastic antimetabolites.
Topics: Aminoacridines; Amsacrine; Animals; Antineoplastic Agents; Azacitidine; Cell Survival; Cytarabine; DNA; DNA Topoisomerases, Type II; Drug Synergism; Humans; Hydroxyurea; In Vitro Techniques; Intercalating Agents; Mice | 1986 |
Use of a trypsin, Peru balsam, and castor oil spray on the oral mucosa: case report and review of the literature.
Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; Balsams; Carcinoma, Squamous Cell; Castor Oil; Cisplatin; Cytarabine; Drug Combinations; Female; Humans; Hydroxyurea; Mouth Mucosa; Mouth Neoplasms; Oral Hygiene; Trypsin; Wound Healing | 1989 |
Bromodeoxyuridine mutagenesis and deoxyribonucleotide pool imbalance in mammalian cells.
Topics: Animals; Base Composition; Bromodeoxyuridine; Cell Line; Cricetinae; Cytarabine; Deoxyadenosines; Deoxycytidine; Deoxyguanosine; Deoxyribonucleotides; DNA; Drug Resistance; Fluorouracil; Hydroxyurea; Melanoma; Mutation; Ribonucleotide Reductases; Sister Chromatid Exchange; Thymidine | 1985 |
Cancer chemotherapy. II.
Topics: Animals; Antineoplastic Agents; Asparaginase; Azathioprine; Bleomycin; Cytarabine; Dactinomycin; Daunorubicin; Dimethylamines; Doxorubicin; Floxuridine; Fluorouracil; Humans; Hydroxyurea; Imidazoles; Mercaptopurine; Mitomycins; Mitotane; Neoplasms; Nitrosourea Compounds; Pipobroman; Procarbazine; Streptonigrin; Streptozocin; Thioguanine; Triazenes; Triazines; Vinblastine; Vincristine | 1972 |
New cancer chemotherapeutic agents.
Topics: Aldehydes; Amides; Amines; Animals; Antineoplastic Agents; Asparaginase; Azacitidine; Azaguanine; Bleomycin; Carmustine; Chlorides; Cyclization; Cyclohexanes; Cytarabine; Cytidine; Doxorubicin; Glycosides; Humans; Hydroxyurea; Imidazoles; Leukemia, Lymphoid; Leukemia, Myeloid; Mice; Nitrosourea Compounds; Picolinic Acids; Platinum; Podophyllotoxin; Streptozocin; Thiosemicarbazones; Triazenes | 1972 |
Immunosuppressive and cytotoxic drugs in dermatology.
Topics: Animals; Antineoplastic Agents; Azathioprine; Azauridine; Bleomycin; Chlorambucil; Cyclophosphamide; Cytarabine; Dactinomycin; Humans; Hydroxyurea; Immunosuppressive Agents; Mercaptopurine; Methotrexate; Procarbazine; Skin Diseases; Skin Neoplasms; Vinblastine; Vincristine | 1974 |
Mechanisms of chromosomal aberration production. 3. Chemicals and ionizing radiation.
Topics: Alkylating Agents; Animals; Caffeine; Chromosome Aberrations; Cyanides; Cytarabine; Deoxyadenosines; DNA; DNA Repair; DNA Replication; DNA, Single-Stranded; Floxuridine; Hydroxyurea; Mitosis; Models, Biological; Mutagens; Radiation Genetics; Recombination, Genetic; Streptonigrin; Theobromine; Theophylline | 1974 |
Monochemotherapy of bronchogenic carcinoma withs special reference to cell type.
Topics: Adenocarcinoma; Alkylating Agents; Antineoplastic Agents; Carcinoma, Bronchogenic; Cytarabine; Dactinomycin; Daunorubicin; Doxorubicin; Floxuridine; Humans; Hydroxyurea; Lung Neoplasms; Mechlorethamine; Methotrexate; Mitomycins; Nitrosourea Compounds; Plicamycin; Porfiromycin; Procarbazine; Streptonigrin; Thiotepa; Vinblastine | 1973 |
Rationale of combination chemotherapy based on preclinical experiments.
Topics: Animals; Antineoplastic Agents; Azaguanine; Carcinoma; Cytarabine; Drug Synergism; Humans; Hydroxyurea; Immunotherapy; Leukemia L1210; Lung Neoplasms; Melanoma; Neoplasms; Thiosemicarbazones; Time Factors | 1973 |
An overview of the status of the nitrosoureas in other tumors.
Topics: Adenocarcinoma; Alkylating Agents; Antineoplastic Agents; Breast Neoplasms; Carcinoma; Carcinoma, Bronchogenic; Carmustine; Cyclohexanes; Cyclophosphamide; Cytarabine; Drug Therapy, Combination; Hodgkin Disease; Humans; Hydroxyurea; Leukemia, Lymphoid; Leukemia, Myeloid; Lymphoma; Melanoma; Melphalan; Multiple Myeloma; Nitrosourea Compounds; Prednisone; Vincristine | 1973 |
[Progress in the drug therapy of cancer].
Topics: Antibiotics, Antineoplastic; Antineoplastic Agents; Asparaginase; Cytarabine; Daunorubicin; Drug Synergism; Humans; Hydrazines; Hydroxyurea; Neoplasms; Nitroso Compounds; Picolinic Acids; Pyrogallol; Quinolines; Streptonigrin; Urea | 1968 |
Cancer chemotherapy.
Topics: Alkaloids; Amides; Animals; Antineoplastic Agents; Asparaginase; Cell Division; Colchicine; Cytarabine; DNA; Griseofulvin; Humans; Hydroxyurea; Mice; Neoplasms; Nucleosides; Thiosemicarbazones; Vinblastine; Vincristine | 1969 |
Chemotherapy and the life cycle of leukaemic cells. A comparison between the growth characteristics of human acute leukaemia and the murine leukaemia L 1210.
Topics: Anilides; Animals; Cell Division; Cyclophosphamide; Cytarabine; DNA, Neoplasm; Fluorouracil; Humans; Hydroxyurea; In Vitro Techniques; Leukemia; Leukemia L1210; Leukemia, Lymphoid; Mechlorethamine; Mercaptopurine; Methotrexate; Mice; Mitosis; Nitroso Compounds; Prednisone; Thymidine; Time Factors; Tritium; Vinblastine; Vincristine | 1969 |
[Cytostatic therapy of acute leukemia (review of the literature)].
Topics: Antibiotics, Antineoplastic; Antineoplastic Agents; Asparaginase; Cyclophosphamide; Cytarabine; Drug Synergism; Humans; Hydroxyurea; Leukemia; Vinblastine; Vincristine | 1969 |
[New principles of treatment in acute leukemia].
Topics: Adolescent; Adult; Antineoplastic Agents; Central Nervous System Diseases; Child; Cyclophosphamide; Cytarabine; Female; Guanidines; Humans; Hydroxyurea; Leukemia, Lymphoid; Leukemia, Myeloid, Acute; Leukopenia; Male; Mercaptopurine; Methotrexate; Middle Aged; Nitroso Compounds; Prednisone; Thrombocytopenia; Urea; Uric Acid; Vincristine | 1970 |
Chronic granulocytic leukemia.
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Asparaginase; Bone Marrow Transplantation; Busulfan; Chromosomes, Human, 21-22 and Y; Cyclophosphamide; Cytarabine; Daunorubicin; Female; Humans; Hydroxyurea; Leukapheresis; Leukemia, Myeloid; Male; Methotrexate; Middle Aged; Palliative Care; Prednisolone; Prednisone; Thioguanine; Vincristine | 1984 |
Drug-induced megaloblastic change.
Topics: Cyclophosphamide; Cytarabine; DNA; Erythrocytes, Abnormal; Floxuridine; Fluorouracil; Folic Acid Antagonists; Humans; Hydroxyurea; Megaloblasts; Methotrexate; Phenytoin; Pyrimethamine; Ribonucleotides; Thymidine Monophosphate; Thymidylate Synthase; Triamterene; Trimethoprim | 1980 |
[Chromosome analysis and TdT determination: important prognostic parameters of blastic crises in chronic myelocytic leukemia].
Topics: Busulfan; Chromosome Aberrations; Cytarabine; DNA Nucleotidylexotransferase; DNA Nucleotidyltransferases; Humans; Hydroxyurea; Karyotyping; Leukemia, Myeloid; Prednisone; Prognosis; Thioguanine; Vincristine | 1982 |
The use of ferrokinetics in the study of experimental anemia.
Topics: Anemia; Animals; Benzene; Cytarabine; Erythropoiesis; Hematopoietic Stem Cells; Humans; Hydroxyurea; Iron; Iron Radioisotopes; Kinetics; Pentobarbital | 1981 |
A syndrome of lymphoblastic lymphoma, eosinophilia, and myeloid hyperplasia/malignancy associated with t(8;13)(p11;q11): description of a distinctive clinicopathologic entity.
Topics: Acute Disease; Adolescent; Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Bone Marrow; Bone Marrow Transplantation; Carboplatin; Chromosomes, Human, Pair 13; Chromosomes, Human, Pair 8; Combined Modality Therapy; Cyclophosphamide; Cytarabine; Daunorubicin; Doxorubicin; Eosinophilia; Etoposide; Fatal Outcome; Female; Humans; Hydroxyurea; Hyperplasia; Ifosfamide; Leukemia, Myeloid; Lymph Nodes; Male; Middle Aged; Mitoxantrone; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Prednisone; Pregnancy; Pregnancy Complications, Neoplastic; Remission Induction; Syndrome; Translocation, Genetic; Vincristine | 1995 |
Chemotherapy and bone marrow transplantation in the treatment of chronic myelogenous leukemia.
Topics: Antineoplastic Agents; Bone Marrow Transplantation; Busulfan; Cytarabine; Humans; Hydroxyurea; Interferon-alpha; Leukemia, Myelogenous, Chronic, BCR-ABL Positive; Transplantation, Autologous; Transplantation, Homologous | 1994 |
[Interferon therapy for chronic myelogenous leukemia].
Topics: Antineoplastic Combined Chemotherapy Protocols; Cytarabine; Daunorubicin; Humans; Hydroxyurea; Immunity, Cellular; Interferon-alpha; Interferon-gamma; Leukemia, Myelogenous, Chronic, BCR-ABL Positive; T-Lymphocytes; Vincristine | 1993 |
Chronic myelogenous leukemia: a review.
Topics: Adult; Antimetabolites, Antineoplastic; Antineoplastic Agents, Alkylating; Antineoplastic Agents, Phytogenic; Antineoplastic Combined Chemotherapy Protocols; Bone Marrow Transplantation; Busulfan; Cytarabine; Drug Therapy, Combination; Harringtonines; Homoharringtonine; Humans; Hydroxyurea; Immunosuppressive Agents; Interferon-alpha; Leukemia, Myelogenous, Chronic, BCR-ABL Positive; Middle Aged; Prognosis; Time Factors | 1996 |
[Recent progress in therapy for chronic myelogenous leukemia].
Topics: Age Factors; Antineoplastic Agents; Bone Marrow Transplantation; Busulfan; Cytarabine; Humans; Hydroxyurea; Interferon-alpha; Leukemia, Myelogenous, Chronic, BCR-ABL Positive; Middle Aged; Randomized Controlled Trials as Topic; Remission Induction; Survival Rate | 1997 |
[Oral antitumor drugs for hematological malignancies].
Topics: Administration, Oral; Antineoplastic Agents; Cytarabine; Etoposide; Hematologic Neoplasms; Humans; Hydroxyurea; Leukemia-Lymphoma, Adult T-Cell; Piperazines; Prodrugs; Tretinoin | 1999 |
The role of interferon-alpha in the treatment of myeloproliferative disorders.
Topics: Clinical Trials as Topic; Cytarabine; Drug Therapy, Combination; Female; Humans; Hydroxyurea; Interferon-alpha; Myeloproliferative Disorders; Polyethylene Glycols; Pregnancy; Pregnancy Complications, Hematologic; Quality of Life | 1999 |
The biology and treatment of chronic myelogenous leukemia.
Topics: Antineoplastic Agents; Benzamides; Busulfan; Clinical Trials as Topic; Combined Modality Therapy; Cytarabine; Graft vs Host Disease; Hematopoietic Stem Cell Transplantation; Humans; Hydroxyurea; Imatinib Mesylate; Interferon-alpha; Leukemia, Myelogenous, Chronic, BCR-ABL Positive; Middle Aged; Piperazines; Pyrimidines; Survival Analysis | 2001 |
Donor cell-derived acute myeloid leukemia developing 14 months after matched unrelated bone marrow transplantation for chronic myeloid leukemia.
Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; Antiviral Agents; Bone Marrow Transplantation; Combined Modality Therapy; Cyclosporine; Cystitis; Cytarabine; Cytomegalovirus Infections; DNA, Neoplasm; Female; Foscarnet; Ganciclovir; Graft vs Host Disease; Granulocyte Colony-Stimulating Factor; Histocompatibility; Humans; Hydroxyurea; Immunosuppressive Agents; Interferon-alpha; Leukemia, Myelogenous, Chronic, BCR-ABL Positive; Leukemia, Myeloid, Acute; Male; Methotrexate; Mitoxantrone; Neoplasms, Second Primary; Prednisolone; Prostaglandins; Remission Induction; Topotecan; Transplantation Conditioning; Transplantation, Homologous; Vidarabine; Whole-Body Irradiation | 2001 |
[Chronic myeloid leukemia--treatment].
Topics: Adult; Antimetabolites, Antineoplastic; Antineoplastic Agents; Benzamides; Cytarabine; Enzyme Inhibitors; Female; Humans; Hydroxyurea; Imatinib Mesylate; Interferon-alpha; Leukemia, Myelogenous, Chronic, BCR-ABL Positive; Male; Piperazines; Protein-Tyrosine Kinases; Pyrimidines; Remission Induction; Risk Factors; Stem Cell Transplantation | 2002 |
Fatal hemorrhagic pneumonia caused by infection due to Kytococcus sedentarius--a pathogen or passenger?
Topics: Actinomycetales; Actinomycetales Infections; Acyclovir; Antineoplastic Combined Chemotherapy Protocols; Bacteremia; Bacterial Translocation; Cefepime; Cephalosporins; Clostridium Infections; Colistin; Cytarabine; Daunorubicin; Drug Therapy, Combination; Etoposide; Fatal Outcome; Hemoptysis; Humans; Hydroxyurea; Immunocompromised Host; Intestinal Mucosa; Leukemia, Myeloid, Acute; Male; Metronidazole; Middle Aged; Neutropenia; Pneumonia, Bacterial; Superinfection; Teicoplanin; Trimethoprim, Sulfamethoxazole Drug Combination | 2004 |
Have all-trans retinoic acid and arsenic trioxide replaced all-trans retinoic acid and anthracyclines in APL as standard of care.
Topics: Adult; Age Factors; Aged; Anthracyclines; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Arsenic Trioxide; Arsenicals; Blood Coagulation Factors; Clinical Trials as Topic; Combined Modality Therapy; Cytarabine; Etoposide; Humans; Hydroxyurea; Idarubicin; Leukemia, Promyelocytic, Acute; Maintenance Chemotherapy; Middle Aged; Mitoxantrone; Multicenter Studies as Topic; Oxides; Platelet Transfusion; Practice Guidelines as Topic; Remission Induction; Risk Assessment; Thioguanine; Treatment Outcome; Tretinoin | 2014 |
Procarbazine, lomustine and vincristine for recurrent high-grade glioma.
Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; Brain Neoplasms; Cytarabine; Dacarbazine; Disease Progression; Disease-Free Survival; Drug Administration Schedule; Glioma; Humans; Hydroxyurea; Lomustine; Methylprednisolone; Middle Aged; Neoplasm Recurrence, Local; Procarbazine; Randomized Controlled Trials as Topic; Temozolomide; Vincristine | 2017 |
Therapy for Chronic Myelomonocytic Leukemia in a New Era.
Topics: Allografts; Cytarabine; Humans; Hydroxyurea; Leukemia, Myelogenous, Chronic, BCR-ABL Positive; Stem Cell Transplantation; World Health Organization | 2017 |
28 trial(s) available for cytarabine and hydroxyurea
| Article | Year |
|---|---|
A comparative trial of daunorubicin, cytosine arabinoside, and thioguanine, and a combination of the three agents for the treatment of acute myelocytic leukemia.
Topics: Adult; Age Factors; Aged; Antineoplastic Agents; Bone Marrow; Clinical Trials as Topic; Cyclophosphamide; Cytarabine; Daunorubicin; Drug Administration Schedule; Drug Synergism; Drug Therapy, Combination; Female; Humans; Hydroxyurea; Leukemia, Myeloid, Acute; Male; Mercaptopurine; Middle Aged; Remission, Spontaneous; Thioguanine | 1979 |
A clinical trial of early splenectomy, hydroxyurea, and cyclic arabinosyl cytosine, vincristine, and prednisone in chronic myeloid leukemia. Italian Cooperative Study Group on Chronic Myeloid Leukemia.
Topics: Adolescent; Adult; Aged; Antineoplastic Agents; Clinical Trials as Topic; Cytarabine; Drug Evaluation; Drug Therapy, Combination; Female; Humans; Hydroxyurea; Leukemia, Myeloid; Liver; Male; Middle Aged; Organ Size; Prednisone; Spleen; Splenectomy; Time Factors; Vincristine | 1975 |
Chronic myelogenous leukemia: a clinical and experimental evaluation of splenectomy and intensive chemotherapy.
Topics: Adult; Antineoplastic Agents; Busulfan; Chromosome Aberrations; Chromosomes, Human, 21-22 and Y; Clinical Trials as Topic; Cytarabine; Daunorubicin; Drug Evaluation; Drug Therapy, Combination; Evaluation Studies as Topic; Female; Humans; Hydroxyurea; Leukemia, Myeloid; Male; Middle Aged; Splenectomy; Thioguanine | 1975 |
Treatment of acute myeloid leukemia in the elderly with low-dose cytarabine, hydroxyurea, and calcitriol.
Topics: Acute Disease; Administration, Oral; Age Factors; Aged; Aged, 80 and over; Bone Marrow; Calcitriol; Cytarabine; Dose-Response Relationship, Drug; Drug Therapy, Combination; Humans; Hydroxyurea; Infusions, Intravenous; Leukemia, Myeloid; Middle Aged | 1992 |
A multicentre study of a randomized therapeutic protocol in previously untreated patients with Ph-positive chronic myelogenous leukaemia: interferon alfa-2b and hydroxyurea with or without cytosine arabinoside , preliminary results.
Topics: Adolescent; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Cytarabine; Female; Humans; Hydroxyurea; Interferon Type I; Leukemia, Myelogenous, Chronic, BCR-ABL Positive; Male; Middle Aged; Recombinant Proteins | 1991 |
[Treatment of acute myeloblastic leukemia in aged patients].
Topics: Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Clinical Trials as Topic; Colony-Stimulating Factors; Cytarabine; Daunorubicin; Humans; Hydroxyurea; Leukemia, Myeloid, Acute; Middle Aged; Palliative Care; Prognosis | 1989 |
[AML-7 study of the value of intensive remission induction in aged patients with acute myelocytic leukemia].
Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Clinical Trials as Topic; Cytarabine; Daunorubicin; Drug Administration Schedule; Humans; Hydroxyurea; Leukemia, Myeloid, Acute; Vincristine | 1985 |
[AML-6 and AML-7 studies on the treatment of acute myelocytic leukemia. Cyclic alternating chemotherapy during remission, and induction of remission and survival of elderly patients].
Topics: Adult; Age Factors; Aged; Aminoacridines; Amsacrine; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Azaguanine; Cytarabine; Daunorubicin; Drug Administration Schedule; Humans; Hydroxyurea; Leukemia, Myeloid, Acute; Middle Aged; Vincristine | 1985 |
[The so-called partial synchronization in the treatment of malignant lymphomas. A clinical study].
Topics: Bleomycin; Cell Division; Clinical Trials as Topic; Cytarabine; Doxorubicin; Fluorouracil; Hodgkin Disease; Humans; Hydroxyurea; Lymphoma; Neoplasm Invasiveness; Remission, Spontaneous; Vinca Alkaloids | 1980 |
Response of chronic myelogenous leukemia patients to COAP-splenectomy. A Southwest Oncology Group study.
Topics: Adolescent; Adult; Age Factors; Aged; Antineoplastic Combined Chemotherapy Protocols; BCG Vaccine; Combined Modality Therapy; Cyclophosphamide; Cytarabine; Female; Humans; Hydroxyurea; Immunotherapy; Leukemia, Myeloid; Male; Middle Aged; Prednisone; Sex Factors; Splenectomy; Vincristine | 1984 |
Immunotherapy maintenance in acute non-lymphocytic leukaemia.
Topics: Acute Disease; Adult; Aged; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; BCG Vaccine; Clinical Trials as Topic; Cytarabine; Daunorubicin; Drug Administration Schedule; Drug Therapy, Combination; Humans; Hydroxyurea; Immunotherapy; Leukemia; Middle Aged; Prednisolone; Prognosis; Random Allocation; Vincristine | 1982 |
Granulocyte-macrophage colony stimulating factor (GM-CSF) priming in the treatment of elderly patients with acute myelogenous leukemia.
Topics: Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Biopsy; Bone Marrow; Cell Cycle; Cytarabine; Disease-Free Survival; Female; Granulocyte-Macrophage Colony-Stimulating Factor; Humans; Hydroxyurea; Leukemia, Myeloid, Acute; Male; Middle Aged; Remission Induction; Survival Rate | 1995 |
Evolving approaches with interferon alfa in chronic myelogenous leukemia.
Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; Cytarabine; Humans; Hydroxyurea; Interferon alpha-2; Interferon-alpha; Leukemia, Myelogenous, Chronic, BCR-ABL Positive; Recombinant Proteins; Treatment Outcome | 1993 |
Long-term follow-up results of alpha interferon therapy in chronic myelogenous leukemia at M. D. Anderson Cancer Center.
Topics: Antineoplastic Combined Chemotherapy Protocols; Combined Modality Therapy; Cytarabine; Daunorubicin; Drug Therapy, Combination; Follow-Up Studies; Humans; Hydroxyurea; Immunologic Factors; Interferon alpha-2; Interferon-alpha; Interferon-gamma; Leukemia, Myelogenous, Chronic, BCR-ABL Positive; Life Tables; Prednisone; Recombinant Proteins; Remission Induction; Survival Analysis; Texas; Treatment Outcome; Vincristine | 1993 |
Successful treatment of accelerated and blastic phase of chronic myeloid leukemia with high-dose interferon alpha and hydroxyurea: a novel approach.
Topics: Acetaminophen; Adult; Aged; Analgesics, Non-Narcotic; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Blast Crisis; Bone Marrow Transplantation; Busulfan; Combined Modality Therapy; Cytarabine; Humans; Hydroxyurea; Interferon-alpha; Leukemia, Myelogenous, Chronic, BCR-ABL Positive; Male; Melphalan; Middle Aged | 1995 |
Ototoxicity in children with malignant brain tumors treated with the "8 in 1" chemotherapy protocol.
Topics: Adolescent; Antineoplastic Combined Chemotherapy Protocols; Brain Neoplasms; Chemotherapy, Adjuvant; Child; Child, Preschool; Cisplatin; Combined Modality Therapy; Cyclophosphamide; Cytarabine; Dacarbazine; Drug Administration Schedule; Evaluation Studies as Topic; Female; Follow-Up Studies; Hearing Loss; Humans; Hydroxyurea; Incidence; Infant; Lomustine; Male; Methylprednisolone; Procarbazine; Radiation Injuries; Risk Factors; Vincristine | 1996 |
The treatment of chronic myelogenous leukemia by interferon and cytosine-arabinoside: rational and design of the French trials. French CML Study Group.
Topics: Adult; Aged; Antineoplastic Agents; Combined Modality Therapy; Cytarabine; Drug Tolerance; France; Humans; Hydroxyurea; Interferon alpha-2; Interferon-alpha; Leukemia, Myeloid, Chronic-Phase; Middle Aged; Randomized Controlled Trials as Topic; Recombinant Proteins | 1996 |
Interferon alfa-2b combined with cytarabine versus interferon alone in chronic myelogenous leukemia. French Chronic Myeloid Leukemia Study Group.
Topics: Adolescent; Adult; Aged; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Child; Child, Preschool; Cytarabine; Female; Humans; Hydroxyurea; Interferon alpha-2; Interferon-alpha; Leukemia, Myelogenous, Chronic, BCR-ABL Positive; Male; Middle Aged; Recombinant Proteins; Regression Analysis; Survival Analysis | 1997 |
Long-term follow-up results of alpha-interferon-based regimens in patients with late chronic phase chronic myelogenous leukemia.
Topics: Adolescent; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Cytarabine; Female; Follow-Up Studies; Humans; Hydroxyurea; Interferon Type I; Interferon-alpha; Interferon-gamma; Leukemia, Myelogenous, Chronic, BCR-ABL Positive; Leukemia, Myeloid, Chronic-Phase; Male; Middle Aged; Prognosis; Recombinant Proteins; Time Factors | 1997 |
Regression with bounded outcome score: evaluation of power by bootstrap and simulation in a chronic myelogenous leukaemia clinical trial.
Topics: Antineoplastic Combined Chemotherapy Protocols; Bone Marrow Transplantation; Combined Modality Therapy; Cytarabine; Humans; Hydroxyurea; Interferons; Leukemia, Myelogenous, Chronic, BCR-ABL Positive; Models, Statistical; Odds Ratio; Outcome and Process Assessment, Health Care; Regression Analysis; Remission Induction | 1998 |
A prospective randomized study of alpha-2b interferon plus hydroxyurea or cytarabine for patients with early chronic phase chronic myelogenous leukemia: the International Oncology Study Group CML1 study.
Topics: Adolescent; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Child; Cytarabine; Female; Humans; Hydroxyurea; Interferon alpha-2; Interferon-alpha; Leukemia, Myeloid, Chronic-Phase; Male; Middle Aged; Prospective Studies; Recombinant Proteins; Survival Rate; Treatment Outcome | 2000 |
Synergistic activity of the new ABL-specific tyrosine kinase inhibitor STI571 and chemotherapeutic drugs on BCR-ABL-positive chronic myelogenous leukemia cells.
Topics: Antineoplastic Combined Chemotherapy Protocols; Benzamides; Cytarabine; Dose-Response Relationship, Drug; Drug Synergism; Enzyme Inhibitors; Fusion Proteins, bcr-abl; Humans; Hydroxyurea; Imatinib Mesylate; Leukemia, Myelogenous, Chronic, BCR-ABL Positive; Piperazines; Protein-Tyrosine Kinases; Pyrimidines; Remission Induction | 2001 |
[Imatinib combination therapies--the new CML Study 4].
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Benzamides; Cytarabine; Dose-Response Relationship, Drug; Drug Resistance, Neoplasm; Humans; Hydroxyurea; Imatinib Mesylate; Interferon alpha-2; Interferon-alpha; Leukemia, Myeloid, Chronic-Phase; Middle Aged; Piperazines; Pyrimidines; Recombinant Proteins; Remission Induction; Survival Rate; Treatment Outcome | 2002 |
A randomized study comparing interferon (IFN alpha) plus low-dose cytarabine and interferon plus hydroxyurea (HU) in early chronic-phase chronic myeloid leukemia (CML).
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Cytarabine; Female; Gastrointestinal Diseases; Hematologic Diseases; Humans; Hydroxyurea; Interferon-alpha; Leukemia, Myeloid, Chronic-Phase; Life Tables; Male; Middle Aged; Nervous System Diseases; Recombinant Proteins; Treatment Outcome | 2003 |
A comparison of low-dose cytarabine and hydroxyurea with or without all-trans retinoic acid for acute myeloid leukemia and high-risk myelodysplastic syndrome in patients not considered fit for intensive treatment.
Topics: Acute Disease; Aged; Antineoplastic Combined Chemotherapy Protocols; Cytarabine; Female; Humans; Hydroxyurea; Leukemia, Myeloid; Male; Middle Aged; Myelodysplastic Syndromes; Risk; Survival; Treatment Outcome; Tretinoin | 2007 |
Sequential oral hydroxyurea and intravenous cytosine arabinoside in refractory childhood acute leukemia: a pediatric oncology group phase 1 study.
Topics: Adolescent; Adult; Child; Child, Preschool; Cytarabine; Humans; Hydroxyurea; Infections; Leukemia; Leukemia-Lymphoma, Adult T-Cell; Leukemia, Myeloid, Acute; Liver; Skin; Survival Analysis | 2008 |
Clofarabine in combination with a standard remission induction regimen (cytosine arabinoside and idarubicin) in patients with previously untreated intermediate and bad-risk acute myelogenous leukemia (AML) or high-risk myelodysplastic syndrome (HR-MDS): p
Topics: Adenine Nucleotides; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Arabinonucleosides; Clofarabine; Consolidation Chemotherapy; Cytarabine; Fatigue; Female; Gastrointestinal Diseases; Humans; Hydroxyurea; Hyperbilirubinemia; Idarubicin; Leukemia, Myeloid, Acute; Male; Middle Aged; Myelodysplastic Syndromes; Remission Induction; Risk; Treatment Outcome | 2014 |
A phase 1 trial evaluating thioridazine in combination with cytarabine in patients with acute myeloid leukemia.
Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Cytarabine; Dopamine D2 Receptor Antagonists; Female; Humans; Hydroxyurea; Leukemia, Myeloid, Acute; Male; Middle Aged; Thioridazine | 2018 |
488 other study(ies) available for cytarabine and hydroxyurea
| Article | Year |
|---|---|
Structure-activity relationships of antineoplastic agents in multidrug resistance.
Topics: Animals; Antineoplastic Agents; Cell Line; Cell Survival; Cricetinae; Dactinomycin; Drug Resistance; Leukemia L1210; Mice; Regression Analysis; Structure-Activity Relationship; Tumor Cells, Cultured | 1990 |
Comparative structure-activity relationships of antifolate triazines inhibiting murine tumor cells sensitive and resistant to methotrexate.
Topics: Animals; Chemical Phenomena; Chemistry, Physical; Chickens; Drug Resistance; Folic Acid Antagonists; Humans; Leukemia L5178; Leukemia, Experimental; Mathematics; Methotrexate; Mice; Structure-Activity Relationship; Triazines | 1984 |
Assessment of the health effects of chemicals in humans: II. Construction of an adverse effects database for QSAR modeling.
Topics: Adverse Drug Reaction Reporting Systems; Artificial Intelligence; Computers; Databases, Factual; Drug Prescriptions; Drug-Related Side Effects and Adverse Reactions; Endpoint Determination; Models, Molecular; Quantitative Structure-Activity Relationship; Software; United States; United States Food and Drug Administration | 2004 |
Quantitative structure-activity relationship and complex network approach to monoamine oxidase A and B inhibitors.
Topics: Computational Biology; Drug Design; Humans; Isoenzymes; Molecular Structure; Monoamine Oxidase; Monoamine Oxidase Inhibitors; Quantitative Structure-Activity Relationship | 2008 |
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship | 2010 |
Multi-target spectral moment QSAR versus ANN for antiparasitic drugs against different parasite species.
Topics: Antiparasitic Agents; Molecular Structure; Neural Networks, Computer; Parasitic Diseases; Quantitative Structure-Activity Relationship; Species Specificity; Thermodynamics | 2010 |
FDA-approved drug labeling for the study of drug-induced liver injury.
Topics: Animals; Benchmarking; Biomarkers, Pharmacological; Chemical and Drug Induced Liver Injury; Drug Design; Drug Labeling; Drug-Related Side Effects and Adverse Reactions; Humans; Pharmaceutical Preparations; Reproducibility of Results; United States; United States Food and Drug Administration | 2011 |
A multifactorial approach to hepatobiliary transporter assessment enables improved therapeutic compound development.
Topics: Animals; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Transport; Chemical and Drug Induced Liver Injury; Cluster Analysis; Drug-Related Side Effects and Adverse Reactions; Humans; Liver; Male; Multidrug Resistance-Associated Proteins; Pharmacokinetics; Rats; Rats, Sprague-Dawley; Recombinant Proteins; Risk Assessment; Risk Factors; Toxicity Tests | 2013 |
R factor elimination from Escherichia coli by hydroxyurea and cytosine arabinoside [proceedings].
Topics: Cytarabine; Drug Resistance, Microbial; Escherichia coli; Hydroxyurea; R Factors | 1976 |
Enhancing effect by metabolic inhibitors on the killing of tumor cells by antibody and complement.
Topics: Animals; Antibodies, Neoplasm; Antigen-Antibody Reactions; Antineoplastic Agents; Azacitidine; Carcinoma, Hepatocellular; Cells, Cultured; Complement System Proteins; Cyclophosphamide; Cytarabine; Dactinomycin; Doxorubicin; Fluorouracil; Guinea Pigs; Hydroxyurea; Liver Neoplasms; Mercaptopurine; Methotrexate; Mitomycins; Neoplasms, Experimental; Puromycin; Vincristine | 1975 |
Character of the stimulatory response of uridine kinase in rat livers to cycloheximide treatment.
Topics: Animals; Azacitidine; Cycloheximide; Cytarabine; Dactinomycin; Enzyme Activation; Hydroxyurea; Kinetics; Liver; Male; Mitomycins; Phosphotransferases; Puromycin; Rats; Starvation; Uridine Kinase | 1975 |
Cell volume growth after cell cycle block with chemotherapeutic agents.
Topics: Anti-Bacterial Agents; Antineoplastic Agents; Bleomycin; Cell Division; Cell Line; Cells, Cultured; Colchicine; Cycloheximide; Cytarabine; Dactinomycin; Dose-Response Relationship, Drug; Hydroxyurea; Kinetics; Puromycin; Thymidine; Vinblastine | 1976 |
The mechanism of sensitivity to phleomycin in growing Escherichia coli cells.
Topics: Anti-Bacterial Agents; Bacterial Proteins; Chloramphenicol; Cytarabine; DNA Repair; DNA Replication; DNA, Bacterial; Drug Resistance, Microbial; Escherichia coli; Hydroxyurea; Mitosis; Phenylethyl Alcohol; Phleomycins; Rifampin; RNA, Bacterial; Thymidine; Thymine; Time Factors; Tryptophan | 1976 |
Cell surface changes in HeLa cells as an indication of cell cycle events.
Topics: Bleomycin; Cell Division; Cell Membrane; Cytarabine; HeLa Cells; Humans; Hydrocortisone; Hydroxyurea; Microscopy, Electron, Scanning; Mitomycins; Mitosis; Thymidine; Time Factors; Vinblastine | 1976 |
Hair growth inhibition as a method of screening drugs for local antimitotic activity.
Topics: Animals; Antineoplastic Agents; Bleomycin; Colchicine; Cyclophosphamide; Cytarabine; Drug Evaluation, Preclinical; Fluorouracil; Guinea Pigs; Hair; Hydroxyurea; Injections, Intradermal; Mechlorethamine; Methotrexate; Mitosis; Thiotepa; Vincristine | 1977 |
Regulation of herpesvirus thymidine kinase activity in LM(TK) cells transformed by ultraviolet light-irradiated herpes simplex virus.
Topics: Cell Line; Cell Transformation, Neoplastic; Clone Cells; Cycloheximide; Cytarabine; Dactinomycin; Deoxyadenosines; Enzyme Induction; Epitopes; Herpesviridae; Hydroxyurea; Simplexvirus; Thymidine Kinase; Ultraviolet Rays; Vaccinia virus | 1977 |
In vitro induction of polyclonal killer T cells with 2-mercaptoethanol and the essential role of macrophages in this process.
Topics: Animals; Antigens, Neoplasm; Burkitt Lymphoma; Cell Division; Cells, Cultured; Clone Cells; Cytarabine; Cytotoxicity Tests, Immunologic; DNA; Epitopes; Female; Hydroxyurea; Immunity, Cellular; In Vitro Techniques; Leukemia, Experimental; Macrophages; Mast-Cell Sarcoma; Mercaptoethanol; Mice; Mice, Inbred Strains; Neoplasms, Experimental; Plasmacytoma; T-Lymphocytes | 1977 |
Effect of various antitumor drugs on energetic processes.
Topics: Animals; Antineoplastic Agents; Bleomycin; Brain; Carcinoma, Ehrlich Tumor; Carmustine; Cytarabine; Daunorubicin; Doxorubicin; Glycolysis; Hydroxyurea; In Vitro Techniques; Liver; Oxygen Consumption; Peptichemio; Rats; Teniposide | 1976 |
Differential sensitivities of five rat hepatoma cell lines to anticancer drugs.
Topics: Animals; Antineoplastic Agents; Bleomycin; Carcinoma, Hepatocellular; Cell Line; Cell Survival; Cytarabine; Doxorubicin; Drug Resistance; Hydroxyurea; Liver Neoplasms; Lomustine; Neoplasms, Experimental; Rats; Semustine | 1978 |
Induced synthesis of immunoglobulin messenger RNA accompanies induction of immunoglobulin production in cultured mouse spleen cells.
Topics: Animals; Cycloheximide; Cytarabine; Dactinomycin; DNA; Escherichia coli; Globins; Hydroxyurea; Immunoglobulin kappa-Chains; Immunoglobulin Light Chains; Lipopolysaccharides; Male; Mice; RNA, Messenger; Spleen; Uridine | 1978 |
Effects of thymidine analogs upon growth control in cultured hormone-dependent ray ovary cells.
Topics: Animals; Bromodeoxyuridine; Cell Differentiation; Cell Division; Cell Line; Cell Survival; Culture Media; Cytarabine; Deoxyuridine; DNA; Female; Floxuridine; Hormones; Hydroxyurea; Idoxuridine; Kinetics; Ovarian Neoplasms; Rats; Thymidine | 1975 |
Control of normal differentiation of myeloid leukemic cells. VI. Inhibition of cell multiplication and the formation of macrophages.
Topics: Animals; Blood; Bromodeoxyuridine; Cell Adhesion; Cell Differentiation; Cell Division; Cell Movement; Clone Cells; Cycloheximide; Cytarabine; Dactinomycin; Endotoxins; Floxuridine; Hydroxyurea; Idoxuridine; Leukemia, Myeloid; Macrophages; Mice; Mitomycins; Thymidine; Vinblastine | 1975 |
Changes in the organization of chromosomes during the cell cycle: response to ultraviolet light.
Topics: Autoradiography; Caffeine; Cell Division; Cell Fusion; Cell Survival; Chromosomes; Cytarabine; DNA, Neoplasm; Floxuridine; HeLa Cells; Humans; Hydroxyurea; Mitosis; Radiation Effects; Thymidine; Tritium; Ultraviolet Rays | 1975 |
The reversible inhibition of myoblast fusion by ethidium bromide (EB).
Topics: Cell Fusion; Cells, Cultured; Chloramphenicol; Cytarabine; DNA; Dose-Response Relationship, Drug; Ethidium; Floxuridine; Hydroxyurea; Methotrexate; Protein Biosynthesis; Rifampin; RNA; Thymidine | 1976 |
Cell proliferation kinetics and drug sensitivity of exponential and stationary populations of cultured L1210 cells.
Topics: Amino Acids; Animals; Antineoplastic Agents; Carmustine; Cell Division; Cell Survival; Cells, Cultured; Culture Media; Cytarabine; Dactinomycin; Daunorubicin; DNA, Neoplasm; Doxorubicin; Glucose; Hydroxyurea; Kinetics; Leukemia L1210; Lomustine; Streptozocin; Thymidine; Vincristine | 1977 |
Stimulation of human chorionic gonadotropin by JAr line choriocarcinoma after inhibition of DNA synthesis.
Topics: Cell Line; Choriocarcinoma; Chorionic Gonadotropin; Cycloheximide; Cytarabine; DNA, Neoplasm; Dose-Response Relationship, Drug; Female; Floxuridine; Humans; Hydroxyurea; Methotrexate; Neoplasm Proteins; Neoplasms, Experimental; Pregnancy; Uterine Neoplasms | 1979 |
Nerve outgrowth by dorsal root ganglia in vitro: stimulation by inhibitors of DNA metabolism in the absence of exogenous nerve growth factor.
Topics: Animals; Arabinose; Cells, Cultured; Chick Embryo; Cytarabine; Cytosine; Dose-Response Relationship, Drug; Floxuridine; Ganglia, Spinal; Hydroxyurea; Nerve Growth Factors; Thymidine | 1979 |
In vitro synthesis of DNA in nuclei isolated from herpes simplex virus-infected cells, untreated and treated with metabolic inhibitors.
Topics: Adenine Nucleotides; Animals; Anti-Bacterial Agents; Camptothecin; Cell Line; Cell Nucleus; Centrifugation, Density Gradient; Culture Media; Cytarabine; Cytosine Nucleotides; Deoxyadenosines; DNA; DNA, Viral; Guanine Nucleotides; Haplorhini; Hydroxyurea; Kidney; Magnesium; Simplexvirus; Sucrose; Thymine Nucleotides; Tritium; Virus Replication | 1975 |
Cycloheximide induction of xenotropic type C virus from synchronized mouse cells: metabolic requirements for virus activation.
Topics: Animals; Cell Division; Cell Line; Cycloheximide; Cytarabine; Dactinomycin; DNA, Neoplasm; Hydroxyurea; Idoxuridine; Mice; Mice, Inbred Strains; Mitomycins; Retroviridae; RNA, Neoplasm; Sarcoma, Experimental; Virus Replication | 1975 |
Determination of limb bud chondrocytes during a transient block of the cell cycle.
Topics: Aminopterin; Animals; Bucladesine; Cartilage; Cell Adhesion; Cell Differentiation; Cell Division; Cells, Cultured; Chick Embryo; Colchicine; Cytarabine; DNA; Extremities; Floxuridine; Hydroxyurea; Theophylline; Thymidine | 1975 |
Replication of polyoma DNA: effects of hydroxyurea and arabinosyl cytosine.
Topics: Centrifugation, Density Gradient; Cytarabine; DNA Replication; DNA, Circular; DNA, Viral; Electrophoresis, Agar Gel; Hydroxyurea; Molecular Weight; Polyomavirus | 1975 |
Biochemical and physiological mechanisms in glucocorticoid hormone induction of mouse mammary tumor virus.
Topics: Antigens, Viral; Clone Cells; Cycloheximide; Cytarabine; Dactinomycin; Dexamethasone; DNA; DNA-Directed RNA Polymerases; DNA, Viral; Hydroxyurea; Kinetics; Mammary Tumor Virus, Mouse; Nucleic Acid Hybridization; Proteins; Receptors, Drug; RNA, Viral; Viral Proteins; Virus Replication | 1976 |
Cell cycle dependence for activation of Epstein-Barr virus by inhibitors of protein synthesis or medium deficient in arginine.
Topics: Antigens, Viral; Arginine; Cell Division; Cell Line; Culture Media; Cycloheximide; Cytarabine; DNA, Neoplasm; DNA, Viral; Herpesvirus 4, Human; Hydroxyurea; Neoplasm Proteins; Puromycin; RNA, Neoplasm; Virus Replication | 1976 |
Common precursor pathways of Herpes DNA and of repair synthesis in ultraviolet irradiated cells.
Topics: Cells, Cultured; Cytarabine; Deoxyribonucleosides; DNA Repair; DNA, Viral; Floxuridine; Hydroxyurea; Phosphotransferases; Simplexvirus; Ultraviolet Rays; Virus Replication | 1977 |
Analysis of herpes simplex virus DNA synthesized in infected nuclei by chromatography on benzoylated naphthoylated DEAE cellulose columns.
Topics: Arginine; Cell Line; Cell Nucleus; Chromatography, DEAE-Cellulose; Cytarabine; DNA Replication; DNA, Viral; Hydroxyurea; Molecular Weight; Simplexvirus | 1976 |
Nuclear localisation of DNA polymerase alpha and DNA synthesis in polyoma virus infected mouse cells.
Topics: Animals; Cell Nucleus; Cells, Cultured; Cytarabine; Cytoplasm; DNA Replication; DNA-Directed DNA Polymerase; DNA, Neoplasm; DNA, Viral; Floxuridine; Hydroxyurea; Polyomavirus; Tumor Virus Infections | 1977 |
[Combined action of DNA-synthesis inhibitors on the reproduction of DNA viruses].
Topics: Cytarabine; Distamycins; DNA Replication; DNA Viruses; DNA, Viral; Drug Combinations; Herpesvirus 1, Suid; Hydroxyurea; Orotic Acid; Vaccinia virus; Virus Replication | 1977 |
Transport and metabolism of deoxycytidine and 1-beta-D-arabinofuranosylcytosine into cultured Novikoff rat hepatoma cells, relationship to phosphorylation, and regulation of triphosphate synthesis.
Topics: Animals; Biological Transport, Active; Carcinoma, Hepatocellular; Cells, Cultured; Cytarabine; Deoxycytidine; Deoxyribonucleotides; DNA, Neoplasm; Feedback; Hydroxyurea; Liver Neoplasms; Neoplasms, Experimental; Oxidative Phosphorylation; Rats; Thymidine | 1978 |
Augmentation of the in vitro humoral immune response by pharmacologic agents. II: comparison of the effects of antiproliferative agents with DBcAMP.
Topics: Animals; Antibody Formation; Bucladesine; Cells, Cultured; Cyclic AMP; Cytarabine; Demecolcine; Dose-Response Relationship, Drug; Female; Hydroxyurea; Mice; Spleen | 1979 |
Animal cells reversibly permeable to small molecules.
Topics: Cell Cycle; Cell Line; Cell Membrane Permeability; Cytarabine; Deoxyribonucleotides; DNA; DNA Replication; Hydroxyurea; Protein Biosynthesis; Ribonucleotide Reductases; RNA; Saline Solution, Hypertonic | 1978 |
Selective killing of oncogenic human cells cocultivated with normal human fibroblasts.
Topics: Cell Cycle; Cell Survival; Cells, Cultured; Cytarabine; Fibroblasts; HeLa Cells; Histidinol; Humans; Hydroxyurea; Imidazoles; Theophylline | 1978 |
Results of treatment of Ph'+ chronic myelogenous leukemia with an intensive treatment regimen (L-5 protocol).
Topics: Adolescent; Adult; Asparaginase; Cell Transformation, Neoplastic; Chromosomes, Human, 21-22 and Y; Cytarabine; Female; Humans; Hydroxyurea; Leukemia, Myeloid; Male; Middle Aged; Radiography; Spleen; Splenectomy; Thioguanine | 1979 |
[Splenectomy and polychemotherapy in chronic myelosis].
Topics: Busulfan; Cytarabine; Daunorubicin; Humans; Hydroxyurea; Leukemia, Myeloid; Mercaptopurine; Methotrexate; Mitobronitol; Prognosis; Splenectomy; Vincristine | 1979 |
Dose-dependent cytokinetic changes following 1-beta-D-arabinofuranosylcytosine and hydroxyurea in L1210 and S-180 in vivo.
Topics: Animals; Cytarabine; DNA, Neoplasm; Female; Hydroxyurea; Leukemia L1210; Male; Mice | 1978 |
Curing of an R factor from Escherichia coli by hydroxyurea and cytosine arabinoside.
Topics: Culture Media; Cytarabine; DNA, Bacterial; Dose-Response Relationship, Drug; Drug Resistance, Microbial; Escherichia coli; Hydroxyurea; R Factors | 1978 |
Improvement of therapeutic effects of cytosine-arabinoside on Walker-carcinosarcoma after different synchronization with hydroxyurea.
Topics: Animals; Carcinoma 256, Walker; Cell Cycle; Cytarabine; Cytological Techniques; Hydroxyurea; Rats | 1978 |
Engraftment of RH-positive marrow in a recipient with RH antibody.
Topics: Acute Disease; Adult; Blood Group Incompatibility; Bone Marrow Cells; Bone Marrow Transplantation; Cell Survival; Cyclophosphamide; Cytarabine; Graft Survival; Humans; Hydroxyurea; Injections, Spinal; Isoantibodies; Leukemia, Lymphoid; Male; Methotrexate; Patient Isolators; Rh-Hr Blood-Group System | 1977 |
[Chemotherapy in solid transplantation tumors following synchronization (author's transl)].
Topics: Animals; Carcinoma 256, Walker; Cell Cycle; Cyclophosphamide; Cytarabine; Hydroxyurea; Male; Neoplasms, Experimental; Neurofibroma; Rats; Time Factors; Vincristine | 1979 |
Effects of intranasal irrigation with mitotic inhibitors on olfactory behavior and biochemistry in mice.
Topics: Administration, Intranasal; Animals; Behavior, Animal; Carnosine; Chemoreceptor Cells; Colchicine; Cytarabine; Discrimination Learning; DNA; Ethidium; Hydroxyurea; Mice; Mitosis; Nasal Mucosa; Nerve Degeneration; Neurons; Olfactory Bulb; Peptide Synthases; Smell | 1979 |
Some effects of chemotherapeutic drugs on bone marrow stem cells. I. The long-term effects of phase-specific drugs on mouse bone marrow stem cells.
Topics: Animals; Bone Marrow; Cell Cycle; Colony-Forming Units Assay; Cytarabine; Female; Hematopoietic Stem Cells; Hydroxyurea; Interphase; Leukocyte Count; Mice; Mice, Inbred CBA; Models, Biological; Time Factors | 1979 |
Effect of some cytostatics on the haemopoietic stem cells (CFUs) in blood.
Topics: Animals; Antineoplastic Agents; Blood Cell Count; Colchicine; Colony-Forming Units Assay; Cytarabine; Female; Hematopoietic Stem Cells; Hematopoietic System; Hydroxyurea; Methotrexate; Mice; Vinblastine; Vincristine | 1979 |
Differential cell-cycle-dependent inhibition of DNA synthesis by hydroxyurea and cytosine arabinoside in cultured L5178Y mouse lymphoma cells.
Topics: Animals; Cell Cycle; Cell Line; Cytarabine; DNA, Neoplasm; Hydroxyurea; Leukemia L5178; Leukemia, Experimental; Mice; Mitosis | 1979 |
Differential lethal effects of both cytosine arabinoside and hydroxyurea on jejunal crypt cells and testosterone-stimulated accessory sex glands.
Topics: Animals; Castration; Cell Division; Cytarabine; DNA; Hydroxyurea; Jejunum; Male; Rats; Seminal Vesicles; Testosterone; Thymidine; Tritium | 1979 |
Secondary activities of diverse inhibitors potentiate the response of hamster embryo cultures to a mitotic stimulus.
Topics: Animals; Blood; Cattle; Cell Line; Cricetinae; Culture Media; Cycloheximide; Cytarabine; Dactinomycin; DNA; Epithelial Cells; Epithelium; Fibroblasts; Hydroxyurea; Mesocricetus; Mitosis; Mitotic Index; Stimulation, Chemical; Time Factors | 1977 |
Biological and biophysical characteristics of mouse adenovirus, strain FL.
Topics: Adenoviridae; Animals; Antigens, Viral; Capsid; Cell Line; Cross Reactions; Culture Techniques; Cytarabine; Hot Temperature; Hydroxyurea; Idoxuridine; Kidney; Mice; Trypsin; Virus Replication | 1977 |
Description of a permeable eukaryotic cell system to study agents affecting DNA synthesis: demonstration that cytembena is a direct inhibitor of replicative DNA synthesis.
Topics: Acrylates; Cell Membrane Permeability; Cytarabine; Daunorubicin; DNA; DNA Replication; Hydroxyurea; L Cells | 1977 |
The characteristics of enhanced DNA synthesis in L cells treated with interferon and arginine-deprived.
Topics: Arginine; Cell Nucleus; Cytarabine; Dactinomycin; DNA; Hydroxyurea; Interferons; L Cells; Protein Biosynthesis; Puromycin; RNA | 1977 |
Effects of antipsoriasis drugs and metabolic inhibitors on the growth of epidermal cells in culture.
Topics: Animals; Anthralin; Antimetabolites; Azauridine; Cell Division; Cells, Cultured; Cycloheximide; Cytarabine; Dactinomycin; Daunorubicin; Guinea Pigs; Hydroxyurea; Methotrexate; Mycophenolic Acid; Psoriasis; Puromycin; Skin | 1978 |
Effects of the inhibition of DNA synthesis on hypertrophying skeletal muscle.
Topics: Animals; Collagen; Cytarabine; DNA; Hydroxyurea; Hypertrophy; Male; Muscles; Rats; RNA | 1978 |
Response of quiescent and cycling CFU to stimulation.
Topics: Animals; Antigens; Bone Marrow Cells; Cell Division; Clone Cells; Cytarabine; DNA; Female; Hydroxyurea; Mice; Mice, Inbred Strains | 1978 |
Cytoplasmic control of histone messenger RNA translation is not mediated through protein phosphorylation.
Topics: Cytarabine; HeLa Cells; Histones; Hydroxyurea; Molecular Weight; Phosphates; Phosphorylation; Protein Biosynthesis; RNA, Messenger | 1978 |
A new anti-cancer principle isolated from Gymnosporia rothiana Laws, and its use in attaining cures in L1210 leukaemia in combination with "S" phase sensitive drugs.
Topics: Animals; Antineoplastic Agents; Cytarabine; Drug Evaluation, Preclinical; Drug Synergism; Drug Therapy, Combination; Fluorouracil; Hydroxyurea; Interphase; Leukemia L1210; Mice; Plants | 1978 |
Carcinogen-induced immunoreactivity to antinucleoside antibodies in HeLa cells.
Topics: Acetoxyacetylaminofluorene; Anthracenes; Antibodies, Antinuclear; Antigen-Antibody Reactions; Benzopyrenes; Carcinogens; Cycloheximide; Cytarabine; Dactinomycin; DNA, Neoplasm; Dose-Response Relationship, Drug; Fluorescent Antibody Technique; HeLa Cells; Hydroxyurea; Methylnitronitrosoguanidine; Neoplasm Proteins; Puromycin | 1976 |
Murine pulmonary adenoma bioassay of potentially effective agents against slow-growing solid tumors.
Topics: Adenoma; Animals; Antineoplastic Agents; Cell Division; Cell Survival; Cells, Cultured; Cytarabine; Doxorubicin; Drug Evaluation, Preclinical; Female; Humans; Hydroxyurea; Lung Neoplasms; Male; Mice; Mice, Inbred A; Neoplasms, Experimental; Urethane | 1977 |
Alteration of rat bone marrow megakaryocytes following administration of cytosine arabinoside, daunomycin and hydroxyurea.
Topics: Animals; Blood Cell Count; Blood Platelets; Bone Marrow; Bone Marrow Cells; Cytarabine; Daunorubicin; Hydroxyurea; Megakaryocytes; Rats | 1977 |
The relationship between the formation of inclusions and viral DNA synthesis in adenovirus 12-infected cells.
Topics: Adenoviridae; Cell Line; Cell Nucleus; Cytarabine; DNA, Viral; Genes; Hydroxyurea; Inclusion Bodies, Viral; Mutation; Temperature; Viral Proteins | 1977 |
Evidence that the coupling of histone gene expression and DNA synthesis in HeLa S3 cells is not mediated at the transscriptional level.
Topics: Chromatin; Cytarabine; DNA Replication; HeLa Cells; Histones; Hydroxyurea; Kinetics; Nucleic Acid Hybridization; Protein Biosynthesis; Transcription, Genetic | 1977 |
DNA synthesis in isolated lymphocyte nuclei. Effects of megaloblastic anaemia due to folate or vitamin B-12 deficiency or antimetabolite drugs.
Topics: Adenosine Triphosphate; Adult; Aged; Anemia, Macrocytic; Anemia, Megaloblastic; Cell Nucleus; Cytarabine; DNA; DNA Replication; DNA-Directed DNA Polymerase; Ethylmaleimide; Female; Fluorouracil; Folic Acid Deficiency; Humans; Hydroxyurea; Kinetics; Lectins; Lymphocyte Activation; Lymphocytes; Male; Methotrexate; Middle Aged; Thymine Nucleotides; Vitamin B 12 Deficiency | 1977 |
DNA damage in ultraviolet-irradiated HeLa and CHO-Kl cells examined by alkaline lysis and hydroxyapatite chromatography.
Topics: Alkalies; Cells, Cultured; Chromatography; Cytarabine; DNA; DNA Repair; DNA, Single-Stranded; HeLa Cells; Humans; Hydroxyapatites; Hydroxyurea; Mitosis; Ultraviolet Rays; X-Rays | 1977 |
Toxicity of antitumor agents on hemopoietic colony forming cells.
Topics: Animals; Antineoplastic Agents; Bone Marrow; Bone Marrow Cells; Cells, Cultured; Cyclophosphamide; Cytarabine; Female; Femur; Hematopoietic Stem Cells; Hydroxyurea; Mercaptopurine; Methotrexate; Mice; Mice, Inbred Strains; Spleen | 1976 |
Direct induction by estradiol on vitellogenin synthesis in organ cultures of male Xenopus laevis liver.
Topics: Albumins; Animals; Cytarabine; Dactinomycin; Dose-Response Relationship, Drug; Estradiol; Hydroxyurea; Kinetics; Lipoproteins; Liver; Male; Organ Culture Techniques; Protein Biosynthesis; Vitellogenins; Xenopus | 1976 |
Proliferation rate of haemopoietic stem cells after damage by several cytostatic agents.
Topics: Animals; Cell Division; Colchicine; Cytarabine; Dose-Response Relationship, Radiation; Female; Hematopoietic Stem Cells; Hydroxyurea; Methotrexate; Mice | 1976 |
Effect of rate of replication upon transcription in chick embryo limb bud mesenchyme cells in organ culture.
Topics: Animals; Canavanine; Cell Differentiation; Cell Division; Chick Embryo; Chromatin; Connective Tissue; Cycloheximide; Cytarabine; Depression, Chemical; DNA; DNA Replication; Extremities; Hydroxyurea; Organ Culture Techniques; Protein Biosynthesis; RNA; Time Factors; Transcription, Genetic | 1976 |
Treatment of therapy-resistant acute myeloid leukaemia with 7 and 8 cytostatics.
Topics: Adolescent; Adult; Aged; Candidiasis; Cyclophosphamide; Cytarabine; Daunorubicin; Drug Resistance; Drug Therapy, Combination; Esophagitis, Peptic; Female; Humans; Hydroxyurea; Leukemia, Myeloid, Acute; Leukocyte Count; Leukopenia; Male; Mercaptopurine; Methotrexate; Middle Aged; Prednisolone; Stomach Ulcer; Thioguanine; Vincristine | 1975 |
Treatment of acute leukemia in adults.
Topics: Adolescent; Adult; Aged; Asparaginase; Carmustine; Child; Cytarabine; Daunorubicin; Female; Humans; Hydroxyurea; Leukemia, Lymphoid; Leukemia, Monocytic, Acute; Leukemia, Myeloid, Acute; Male; Methotrexate; Middle Aged; Remission, Spontaneous; Thioguanine; Vincristine | 1975 |
DNA-RNA hybrid in cells infected by murine leukemia virus.
Topics: Base Sequence; Cell Nucleus; Cells, Cultured; Cytarabine; Cytoplasm; Depression, Chemical; DNA; DNA, Viral; Hydroxyurea; Molecular Weight; Nucleic Acid Hybridization; Rauscher Virus; RNA, Viral; Time Factors | 1975 |
Non-Hodgkin's lymphoma in children: results of treatment with LSA2-L2 protocol.
Topics: Adolescent; Antineoplastic Agents; Asparaginase; Bone Neoplasms; Child; Child, Preschool; Cyclophosphamide; Cytarabine; Daunorubicin; Drug Therapy, Combination; Female; Humans; Hydroxyurea; Leukemia; Leukemia, Lymphoid; Lymph Nodes; Lymphoma; Male; Mediastinal Neoplasms; Methotrexate; Nasopharyngeal Neoplasms; Ovarian Neoplasms; Skin Neoplasms; Stomach Neoplasms; Thioguanine; Vincristine | 1975 |
Differentiation of erythroleukemic cells in the presence of inhibitors of DNA synthesis.
Topics: Butyrates; Cell Differentiation; Cell Line; Cytarabine; DNA Replication; DNA, Neoplasm; Hemoglobins; Hydroxyurea; Leukemia, Erythroblastic, Acute | 1975 |
[Pharmakokinetics of hydroxy-urea. Therapy of acute myeoblastic leukemias using synchronization and recruitment effects (author' transl)].
Topics: Administration, Oral; Adult; Cell Division; Cytarabine; DNA, Neoplasm; Half-Life; Humans; Hydroxyurea; Kinetics; Leukemia, Myeloid, Acute; Middle Aged; Time Factors | 1976 |
Chemotherapy of acute lymphoblastic leukemia in children.
Topics: Adolescent; Antineoplastic Agents; Asparaginase; Central Nervous System Diseases; Child; Child, Preschool; Cyclophosphamide; Cytarabine; Daunorubicin; Drug Therapy, Combination; Female; Humans; Hydroxyurea; Infant; Injections, Spinal; Leukemia, Lymphoid; Male; Methotrexate; Nitrosourea Compounds; Prednisone; Remission, Spontaneous; Thioguanine; Vincristine | 1976 |
A simultaneous study of bone marrow, spleen, and liver in chronic myeloid leukemia: evidence for differences in cell composition and karyotypes.
Topics: Adolescent; Adult; Bone Marrow; Bone Marrow Cells; Cell Count; Cytarabine; Erythroblasts; Erythrocyte Count; Female; Granulocytes; Humans; Hydroxyurea; Leukemia, Myeloid; Leukocyte Count; Liver; Male; Middle Aged; Mitotic Index; Spleen; Splenectomy | 1975 |
Triggering mechanism of B lymphocytes. I. Effect of anti-immunoglobulin and enhancing soluble factor on differentiation and proliferation of B cells.
Topics: Animals; Antibodies, Anti-Idiotypic; Antibody Formation; Antigens; Ascaris; Azides; B-Lymphocytes; Cell Differentiation; Cytarabine; Cytochalasin B; Hydroxyurea; Immunoglobulins; In Vitro Techniques; Injections, Intradermal; Lipopolysaccharides; Lymphocyte Activation; Rabbits; Time Factors | 1975 |
Triggering mechanism of B lymphocytes. II. Induction of ornithine decarboxylase in B cells by anti-immunoglobulin and enhancing soluble factor.
Topics: Animals; Antibodies, Anti-Idiotypic; B-Lymphocytes; Carboxy-Lyases; Cytarabine; Cytochalasin B; Enzyme Induction; Hydrazines; Hydroxyurea; Immunoglobulin Fab Fragments; Immunoglobulins; Ornithine Decarboxylase; Ornithine Decarboxylase Inhibitors; Rabbits; T-Lymphocytes; Time Factors | 1975 |
Differentiation of thymocytes: evidence that induction of the surface phenotype requires transcription and translation.
Topics: Animals; Camptothecin; Cell Differentiation; Cycloheximide; Cytarabine; Dactinomycin; Deoxyadenosines; DNA; Hydroxyurea; In Vitro Techniques; Macromolecular Substances; Mice; Mice, Inbred Strains; Phenotype; Protein Biosynthesis; Protein Precursors; Puromycin; RNA; T-Lymphocytes; Thymus Extracts; Transcription, Genetic | 1976 |
Cellular kinetics in multiple myeloma. A new approach to staging and treatment.
Topics: Azathioprine; Bone and Bones; Bone Neoplasms; Cell Count; Computers; Cytarabine; Diagnosis, Computer-Assisted; Doxorubicin; Humans; Hydroxyurea; Immunoglobulin G; Information Systems; Kinetics; Medical Records; Multiple Myeloma; Myeloma Proteins; Prognosis; Vincristine | 1975 |
Characterization of the replication of Escherichia coli DNA in the absence of protein synthesis: stable DNA replication.
Topics: Aminoglycosides; Anti-Bacterial Agents; Bacterial Proteins; Chloramphenicol; Cytarabine; DNA Replication; DNA, Bacterial; Escherichia coli; Hot Temperature; Hydroxyurea; Models, Biological; Mutation; Nalidixic Acid; Protein Biosynthesis; RNA, Bacterial; Thymine | 1975 |
1-beta-D-arabinofuranosylcytosine-induced chromatid breakage: effect of inhibition of DNA synthesis.
Topics: Animals; Benzimidazoles; Cell Division; Cell Line; Chromatids; Cricetinae; Cycloheximide; Cytarabine; Dactinomycin; Depression, Chemical; DNA; DNA Replication; Fibroblasts; Hydroxyurea; Protein Biosynthesis; RNA; Sulfhydryl Compounds | 1975 |
The lethal actions of antitumor agents in proliferating cell systems in vivo.
Topics: Animals; Antineoplastic Agents; Cell Survival; Cytarabine; DNA; DNA Replication; Epithelial Cells; Epithelium; Hydroxyurea; Intestinal Mucosa; Intestine, Small; Lysosomes; Methotrexate; Mice; Mitosis; Necrosis; Poly I-C; RNA; Vacuoles | 1975 |
Non-Hodgkin's lymphoma in children.
Topics: Adolescent; Asparaginase; Bone Marrow; Brain Neoplasms; Carmustine; Child; Child, Preschool; Cyclophosphamide; Cytarabine; Daunorubicin; Female; Humans; Hydroxyurea; Lymphoma; Male; Methotrexate; Neoplasm Metastasis; Nitrogen Mustard Compounds; Peripheral Nervous System Neoplasms; Prednisone; Prognosis; Thioguanine; Vincristine | 1975 |
DNA synthesis in permeabilized mouse L cells.
Topics: Biological Transport; Cell Membrane Permeability; Cell Nucleus; Cold Temperature; Cytarabine; Dactinomycin; Deoxyribonucleotides; DNA Replication; Ethylmaleimide; Hydroxymercuribenzoates; Hydroxyurea; Kinetics; L Cells; Magnesium; Microscopy, Electron; Ribonucleotides; Thymidine Kinase | 1976 |
Non-Hodgkin's lymphoma in children. A comparative study of two modalities of therapy.
Topics: Adolescent; Antineoplastic Agents; Asparaginase; Carmustine; Child; Child, Preschool; Cyclophosphamide; Cytarabine; Dactinomycin; Daunorubicin; Drug Therapy, Combination; Female; Humans; Hydroxyurea; Lymphoma; Male; Mercaptopurine; Methotrexate; Neoplasm Metastasis; Prednisone; Thioguanine; Vinblastine; Vincristine | 1976 |
Inhibition of intracellular pyrimidine ribonucleotide reduction by deoxycytidine, arabinosylcytosine and hydroxyurea.
Topics: Cell Line; Cytarabine; Deoxycytidine; Hydroxyurea; Oxidation-Reduction; Pyrimidine Nucleotides; Uridine | 1976 |
Synergistic effect of aphidicolin and 1-beta-D-arabinofuranosylcytosine on the repair of gamma-ray-induced DNA damage in normal human fibroblasts.
Topics: Aphidicolin; Centrifugation, Density Gradient; Cobalt Radioisotopes; Cytarabine; DNA; DNA Damage; DNA Repair; Drug Synergism; Fibroblasts; Gamma Rays; Humans; Hydroxyurea; Radiation Dosage; Ultraviolet Rays | 1992 |
The yield of fission neutron-induced chromatid aberrations in G2-stage human lymphocytes: effect of caffeine, hydroxyurea and cytosine arabinoside post-irradiation.
Topics: Caffeine; Chromosome Aberrations; Cytarabine; DNA Damage; DNA Repair; G2 Phase; Humans; Hydroxyurea; Lymphocytes; Neutrons | 1992 |
Cell cycle status of murine megakaryocyte and granulocyte-macrophage colony-forming cells in bone marrow and spleen.
Topics: Animals; Bone Marrow; Bone Marrow Cells; Cell Cycle; Cells, Cultured; Cytarabine; DNA; Female; Granulocytes; Hematopoietic Stem Cells; Hydroxyurea; Macrophages; Megakaryocytes; Mice; Mice, Inbred C57BL; Spleen | 1992 |
Factors affecting the mRNA levels for the non-heme iron and effector-binding subunits of ribonucleotide reductase.
Topics: Animals; Calcium; Cycloheximide; Cytarabine; Dactinomycin; Deoxyadenosines; Gene Expression Regulation, Neoplastic; Hydroxyurea; Leukemia L1210; Metalloproteins; Nonheme Iron Proteins; Protein Biosynthesis; Pyrazoles; Ribonucleotide Reductases; RNA, Messenger; Transcription, Genetic; Tumor Cells, Cultured | 1992 |
Joint actions of developmental toxicants in Xenopus embryos: binary mixtures of DNA synthesis inhibitors.
Topics: Animals; Cytarabine; DNA; Drug Synergism; Embryo, Nonmammalian; Fluorouracil; Hydroxyurea; Teratogens; Xenopus laevis | 1992 |
Non-aggressive therapy for chronic myeloid leukaemia in blastic transformation.
Topics: Acute Disease; Adolescent; Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Blast Crisis; Child; Cytarabine; Daunorubicin; Doxorubicin; Female; Humans; Hydroxyurea; Leukemia; Leukemia, Myeloid, Chronic-Phase; Male; Methotrexate; Middle Aged; Remission Induction; Thioguanine; Vincristine | 1992 |
Compartmentation of dCTP pools disappears after hydroxyurea or araC treatment in lymphocytes.
Topics: Cytarabine; Deoxycytidine; Deoxycytosine Nucleotides; DNA; G1 Phase; Humans; Hydroxyurea; Lymphocytes; Palatine Tonsil; Phospholipids; S Phase; Thymidine | 1992 |
Synergistic inhibition of human gastric carcinoma cell growth by 1-beta-D-arabinofuranosylcytosine and hydroxyurea or 2'-deoxyguanosine in vitro.
Topics: Carcinoma; Cell Death; Cell Division; Colonic Neoplasms; Cytarabine; Deoxyguanosine; Deoxyribonucleotides; Drug Synergism; Humans; Hydroxyurea; In Vitro Techniques; Stomach Neoplasms; Tumor Cells, Cultured | 1992 |
Cytotoxic synergy of cisplatin with concurrent hydroxyurea and cytarabine: summary of an in vitro model and initial clinical pilot experience.
Topics: Administration, Oral; Antineoplastic Combined Chemotherapy Protocols; Carcinoma; Cell Survival; Cisplatin; Cohort Studies; Cytarabine; DNA, Neoplasm; Dose-Response Relationship, Drug; Drug Screening Assays, Antitumor; Drug Synergism; Female; Humans; Hydroxyurea; Infusions, Intravenous; Male; Middle Aged; Pilot Projects; Remission Induction; Tumor Cells, Cultured | 1992 |
Increase in Ara-C sensitivity in Ara-C sensitive and -resistant leukemia by stimulation of the salvage and inhibition of the de novo pathway.
Topics: Cell Division; Cytarabine; Deoxycytidine Kinase; Deoxycytosine Nucleotides; DNA; Drug Resistance; Humans; Hydroxyurea; Leukemia, Myeloid; Tumor Cells, Cultured | 1992 |
Comparison of in vitro activity of epipodophyllotoxins with other chemotherapeutic agents in human medulloblastomas.
Topics: Alkylating Agents; Amsacrine; Cell Division; Cell Survival; Cross-Linking Reagents; Cytarabine; DNA Damage; DNA Topoisomerases, Type II; Drug Resistance; Etoposide; Humans; Hydroxyurea; In Vitro Techniques; Karyotyping; Medulloblastoma; Teniposide; Tumor Cells, Cultured; Vincristine | 1991 |
Fludarabine infusion potentiates arabinosylcytosine metabolism in lymphocytes of patients with chronic lymphocytic leukemia.
Topics: Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Cytarabine; Drug Synergism; Female; Humans; Hydroxyurea; Infusions, Intravenous; Kinetics; Leukemia, Lymphocytic, Chronic, B-Cell; Lymphocytes; Male; Middle Aged; Vidarabine | 1992 |
The mode of action of 1-beta-D-arabinofuranosylcytosine in inhibiting DNA repair; new evidence using a sensitive assay for repair DNA synthesis and ligation in permeable cells.
Topics: Aphidicolin; Binding, Competitive; Cell Membrane Permeability; Cytarabine; Diterpenes; DNA; DNA Damage; DNA Repair; HeLa Cells; Humans; Hydroxyurea; Nucleic Acid Synthesis Inhibitors; Ultraviolet Rays | 1991 |
High-dose melphalan with 6-hydroxydopamine-purged autologous bone marrow transplantation for poor-risk neuroblastoma.
Topics: Adolescent; Adult; Antineoplastic Combined Chemotherapy Protocols; Ascorbic Acid; Bone Marrow Transplantation; Child; Child, Preschool; Combined Modality Therapy; Cyclophosphamide; Cytarabine; Dianhydrogalactitol; Doxorubicin; Female; Fluorouracil; Humans; Hydroxydopamines; Hydroxyurea; Infant; Male; Melphalan; Neoplasm Staging; Neuroblastoma; Oxidopamine; Prognosis; Radiotherapy Dosage; Remission Induction; Survival Rate; Vincristine; Whole-Body Irradiation | 1991 |
Effects of thymidine and hydroxyurea on the metabolism and cytotoxicity of 1-B-D arabinofuranosylcytosine in highly resistant human leukemia cells.
Topics: Arabinofuranosylcytosine Triphosphate; Cell Cycle; Cell Survival; Cytarabine; DNA; Drug Resistance; Humans; Hydroxyurea; In Vitro Techniques; Leukemia, Myeloid; Thymidine; Tumor Cells, Cultured | 1991 |
Selective uptake of toxic nucleoside (125IUdR) by resistant cancer.
Topics: Adenocarcinoma; Animals; Cell Line; Choriocarcinoma; Colon; Colonic Neoplasms; Cytarabine; Drug Resistance; Female; Fluorouracil; Humans; Hydroxyurea; Idoxuridine; Iodine Radioisotopes; Male; Methotrexate; Mice; Mice, Inbred Strains; Neoplasm Transplantation; Uterine Neoplasms | 1991 |
Inhibition of cis-diammine-1,1-cyclobutane dicarboxylatoplatinum(II)-induced DNA interstand cross-link removal and potentiation of cis-diammine-1,1-cyclobutane dicarboxylatoplatinum(II) cytotoxicity by hydroxyurea and 1-beta-D-arabinofuranosylcytosine.
Topics: Animals; Carboplatin; Cell Survival; Colonic Neoplasms; Cytarabine; DNA Repair; DNA, Neoplasm; Drug Synergism; Humans; Hydroxyurea; Mice; Time Factors; Tumor Stem Cell Assay | 1991 |
Mechanism of inhibition of DNA ligase in Ara-C treated cells.
Topics: Adenosine Monophosphate; Arabinofuranosylcytosine Triphosphate; Cytarabine; DNA Ligases; Humans; Hydroxyurea; Leukemia, Myeloid; Tumor Cells, Cultured | 1991 |
Cytogenetics and molecular analysis in chronic myelogenous leukemia patients treated by interferon and chemotherapy.
Topics: Adult; Combined Modality Therapy; Cytarabine; Female; Humans; Hydroxyurea; Interferon Type I; Leukemia, Myelogenous, Chronic, BCR-ABL Positive; Male; Middle Aged; Polymerase Chain Reaction; Remission Induction | 1990 |
Kinetics of the development of accelerated cell-cycle transit resulting from inhibition of DNA replication in the previous cycle.
Topics: Antineoplastic Agents; Aphidicolin; Cell Cycle; Cytarabine; Diterpenes; DNA; DNA Polymerase II; DNA Replication; HeLa Cells; Humans; Hydroxyurea; Interphase; Mitosis; Thymidine | 1990 |
Extrachromosomal recombination in vaccinia-infected cells requires a functional DNA polymerase participating at a level other than DNA replication.
Topics: Animals; beta-Galactosidase; Cells, Cultured; Cytarabine; DNA Replication; DNA-Directed DNA Polymerase; DNA, Viral; Genetic Markers; Hot Temperature; Hydroxyurea; Lac Operon; Mutation; Phosphonoacetic Acid; Plasmids; Recombination, Genetic; Sequence Homology, Nucleic Acid; Vaccinia virus; Virus Replication | 1990 |
The effect of DNA replication on mutation of the Saccharomyces cerevisiae CDC8 gene.
Topics: Arabinonucleotides; Buffers; Caffeine; Cycloheximide; Cytarabine; Cytidine Monophosphate; DNA Replication; DNA, Fungal; Genes, Fungal; Hydroxyurea; Mutation; Phenotype; Phosphates; Saccharomyces cerevisiae; Ultraviolet Rays | 1990 |
Cisplatin preceded by concurrent cytarabine and hydroxyurea: a pilot study based on an in vitro model.
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Cisplatin; Cytarabine; DNA Repair; Drug Administration Schedule; Drug Evaluation; Female; Humans; Hydroxyurea; Male; Middle Aged; Neoplasms; Thrombocytopenia | 1990 |
Biochemical and cytogenetical characterization of Chinese hamster ovary X-ray-sensitive mutant cells xrs 5 and xrs 6. VI. The correlation between UV-induced DNA lesions and chromosomal aberrations, and their modulations with inhibitors of DNA repair synth
Topics: Animals; Cell Line; Chromosome Aberrations; Cricetinae; Cricetulus; Cytarabine; DNA; DNA Damage; DNA Repair; DNA Replication; DNA, Single-Stranded; Hydroxyurea; Mutation; Radiation Tolerance; Ultraviolet Rays; X-Rays | 1990 |
Intensive therapy in elderly patients with acute myeloid leukemia.
Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Cytarabine; Humans; Hydroxyurea; Leukemia, Myeloid, Acute; Remission Induction | 1990 |
The role of excision repair in the removal of transient benzo[a]pyrene-induced DNA lesions in Chinese hamster ovary cells.
Topics: Animals; Benzo(a)pyrene; Cell Line; Cricetinae; Cricetulus; Cytarabine; DNA; DNA Damage; DNA Repair; Female; Hydroxyurea; Kinetics; Male; Ovary | 1990 |
Effects of cytosine arabinoside and hydroxyurea on the synthesis of deoxyribonucleotides and DNA replication in L1210 cells.
Topics: Adenosine; Animals; Cytarabine; Cytidine; Deoxyribonucleotides; DNA Replication; Hydroxyurea; Leukemia L1210; Mice; RNA, Neoplasm; Tumor Cells, Cultured | 1990 |
Postoperative pulmonary leukostasis.
Topics: Aged; Allopurinol; Cytarabine; Drug Therapy, Combination; Humans; Hydroxyurea; Leukemia, Myelogenous, Chronic, BCR-ABL Positive; Leukocytosis; Male; Positive-Pressure Respiration; Postoperative Complications; Respiratory Insufficiency | 1990 |
Hb F production in stressed erythropoiesis: observations and kinetic models.
Topics: Anemia; Animals; Azacitidine; Cell Cycle; Cell Differentiation; Cytarabine; Erythropoiesis; Fetal Hemoglobin; Hematopoietic Stem Cells; Humans; Hydroxyurea; Kinetics; Models, Biological; Time Factors; Transcription, Genetic | 1985 |
Stimulation of F-cell production in patients with sickle-cell anemia treated with cytarabine or hydroxyurea.
Topics: Adult; Anemia, Sickle Cell; Cytarabine; Dose-Response Relationship, Drug; Erythrocyte Count; Erythropoiesis; Fetal Hemoglobin; Hematocrit; Hematopoietic Stem Cells; Humans; Hydroxyurea; Regeneration; Reticulocytes; Stimulation, Chemical | 1985 |
Chemotherapy to increase fetal hemoglobin in patients with sickle cell anemia.
Topics: Anemia, Sickle Cell; Azacitidine; Cytarabine; Fetal Hemoglobin; Humans; Hydroxyurea; Kinetics; Thalassemia | 1985 |
Genotoxicity of formaldehyde and an evaluation of its effects on the DNA repair process in human diploid fibroblasts.
Topics: Bleomycin; Centrifugation, Density Gradient; Cytarabine; Diploidy; DNA; DNA Polymerase I; DNA Repair; Escherichia coli; Fibroblasts; Formaldehyde; Humans; Hydroxyurea; Kinetics; Mutation; Pyrimidine Dimers; Ultraviolet Rays | 1986 |
On the mechanism of Hb F elevations in the baboon by erythropoietic stress and pharmacologic manipulation.
Topics: Anemia, Hemolytic; Animals; Azacitidine; Cytarabine; DNA; Erythropoiesis; Fetal Hemoglobin; Hemorrhage; Hydroxyurea; Leukocyte Count; Methylation; Nucleic Acid Hybridization; Papio; Reticulocytes | 1986 |
Synergistic enhancement by tumor necrosis factor of in vitro cytotoxicity from chemotherapeutic drugs targeted at DNA topoisomerase II.
Topics: Animals; Bleomycin; Cell Line; Cell Survival; Cytarabine; Dactinomycin; DNA Topoisomerases, Type II; Doxorubicin; Drug Synergism; Etoposide; Fibrosarcoma; Glycoproteins; Hydroxyurea; Mice; Recombinant Proteins; Teniposide; Tumor Necrosis Factor-alpha | 1987 |
Intensive combination chemotherapy and interferons in the management of chronic myelogenous leukemia.
Topics: Antineoplastic Combined Chemotherapy Protocols; Busulfan; Cyclophosphamide; Cytarabine; Drug Evaluation; Humans; Hydroxyurea; Interferons; Leukemia, Myeloid; Prednisone; Recombinant Proteins; Retrospective Studies; Vincristine | 1987 |
Mechanism of Hb F stimulation by S-stage compounds. In vitro studies with bone marrow cells exposed to 5-azacytidine, Ara-C, or hydroxyurea.
Topics: Azacitidine; Bone Marrow Cells; Cytarabine; Erythropoiesis; Fetal Hemoglobin; Hematopoietic Stem Cells; Humans; Hydroxyurea; In Vitro Techniques; Interphase | 1988 |
Differential modulation of 1-beta-D-arabinofuranosylcytosine metabolism by hydroxyurea in human leukemic cell lines.
Topics: Arabinofuranosylcytosine Triphosphate; Arabinonucleotides; B-Lymphocytes; Cell Line; Cytarabine; Deoxyadenine Nucleotides; Deoxyadenosines; Deoxycytidine; Deoxycytosine Nucleotides; Humans; Hydroxyurea; Leukemia; T-Lymphocytes; Thymine Nucleotides; Vidarabine Phosphate | 1988 |
Variable DNA methylation changes during differentiation of human melanoma cells.
Topics: Aphidicolin; Azacitidine; Cell Differentiation; Cell Division; Chromatography, High Pressure Liquid; Cytarabine; Decitabine; Diterpenes; DNA; DNA, Neoplasm; Humans; Hydroxyurea; Methylation; Monophenol Monooxygenase; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured | 1988 |
Modulation of glycoprotein hormone alpha-subunit levels, alkaline phosphatase activity, and DNA replication by antimetabolites in HeLa cultures.
Topics: Alkaline Phosphatase; Antimetabolites; Butyrates; Butyric Acid; Cytarabine; DNA Replication; DNA, Neoplasm; Glycoprotein Hormones, alpha Subunit; HeLa Cells; Humans; Hydroxyurea; Kinetics; Methotrexate | 1989 |
Differential response of human and rodent cell lines to chemical inhibition of the repair of potentially lethal damage.
Topics: Adenosine Diphosphate Ribose; Animals; Aphidicolin; Benzamides; Cell Line; Cricetinae; Cricetulus; Cytarabine; Diterpenes; DNA Polymerase II; DNA Repair; Fibroblasts; Humans; Hydroxyurea; Mice; Vidarabine | 1989 |
Differential effect of collaterally sensitive antimetabolites on P388 murine leukemia sensitive and resistant to adriamycin in vitro.
Topics: Animals; Antimetabolites, Antineoplastic; Aphidicolin; Cytarabine; Diterpenes; DNA Polymerase II; DNA, Neoplasm; Doxorubicin; Drug Resistance; Hydroxyurea; Inosine; Leukemia P388; Leukemia, Experimental; Mice; Ribonucleotide Reductases; RNA, Neoplasm; Tumor Cells, Cultured | 1989 |
G2 effects of DNA-repair inhibitors on chromatid-type aberrations in root-tip cells treated with maleic hydrazide and mitomycin C.
Topics: Caffeine; Cell Cycle; Chromosome Aberrations; Chromosomes; Cytarabine; DNA Damage; DNA Repair; Floxuridine; Hydroxyurea; In Vitro Techniques; Interphase; Maleic Hydrazide; Mitomycin; Mitomycins; Plants; Pyridazines; Thymidine | 1989 |
The production of chromosomal alterations in human lymphocytes by drugs known to interfere with the activity of DNA topoisomerase II. I. m-AMSA.
Topics: Amsacrine; Cell Cycle; Cells, Cultured; Chromosome Aberrations; Chromosomes; Culture Media; Cytarabine; DNA Repair; Humans; Hydroxyurea; In Vitro Techniques; Lymphocytes; Sister Chromatid Exchange; Topoisomerase II Inhibitors; X-Rays | 1989 |
The effects of putative DNA repair inhibitors on DNA adduct levels and unscheduled DNA synthesis in rat hepatocytes exposed to 2-acetylaminofluorene.
Topics: 2-Acetylaminofluorene; Animals; Aphidicolin; Cells, Cultured; Cytarabine; Dideoxynucleosides; Diterpenes; DNA Damage; DNA Repair; Hydroxyurea; In Vitro Techniques; Liver; Male; Nalidixic Acid; Nucleic Acid Synthesis Inhibitors; Rats; Topoisomerase I Inhibitors | 1989 |
Characteristics of MNNG induced repair synthesis and DNA synthesis induced by human cytomegalovirus.
Topics: Animals; Cells, Cultured; Cytarabine; Cytomegalovirus; DNA Repair; DNA, Viral; Humans; Hydroxyurea; Methylnitronitrosoguanidine; Mice; Transcription, Genetic | 1989 |
Relationship between cell cycle stage in the fertilized egg of mice and repair capacity for X-ray-induced damage in the sperm.
Topics: Animals; Benzamides; Caffeine; Cell Cycle; Chromosome Aberrations; Cytarabine; DNA Damage; DNA Repair; Hydroxyurea; Male; Metaphase; Mice; Radiation-Sensitizing Agents; Spermatozoa; Zygote | 1989 |
S-phase inhibitors induce vimentin expression in human promonocytic U-937 cells.
Topics: Antigens, Differentiation, Myelomonocytic; Blotting, Northern; Cell Cycle; Cell Differentiation; Cytarabine; Cytoskeleton; Gene Expression Regulation; Humans; Hydroxyurea; Interphase; RNA, Messenger; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured; Vimentin | 1989 |
Ara-CTP metabolism following hydroxyurea or methotrexate treatment in human leukemia cell lines.
Topics: Arabinofuranosylcytosine Triphosphate; Arabinonucleotides; Cytarabine; Deoxycytidine; Deoxycytosine Nucleotides; Drug Synergism; Humans; Hydroxyurea; Leukemia; Leukemia, Promyelocytic, Acute; Methotrexate; Thymine Nucleotides; Tumor Cells, Cultured | 1989 |
Limitations of the therapeutic regimens for myelodysplastic syndrome.
Topics: Adolescent; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Child; Cytarabine; Female; Humans; Hydroxyurea; Male; Middle Aged; Myelodysplastic Syndromes | 1989 |
Modulation of deoxynucleotide metabolism by the deoxycytidylate deaminase inhibitor 3,4,5,6-tetrahydrodeoxyuridine.
Topics: Cell Line; Cytarabine; Cytidine Diphosphate; DCMP Deaminase; Deoxycytidine; Deoxycytidine Kinase; Deoxycytosine Nucleotides; Deoxyuridine; Hydroxyurea; Kinetics; Nucleotide Deaminases; Ribonucleotide Reductases; T-Lymphocytes; Tetrahydrouridine; Thymine Nucleotides | 1989 |
Modification of cell growth-dependent gene transcript levels by sodium butyrate in serum stimulated fibroblasts.
Topics: Animals; Blood; Butyrates; Butyric Acid; Cell Cycle; Cell Division; Cell Line; Culture Media; Cytarabine; Fibroblasts; Gene Expression Regulation; Genes; Hydroxyurea; Mitoguazone; Mutation; RNA, Messenger; Temperature | 1989 |
[UV-induced unscheduled DNA synthesis in differentiated and dedifferentiated lymphocytes from human peripheral blood under the action of DNA-repair and -replication inhibitors].
Topics: Benzamides; Caffeine; Cell Differentiation; Cells, Cultured; Cytarabine; Depression, Chemical; DNA; DNA Repair; DNA Replication; Drug Interactions; Humans; Hydroxyurea; Lymphocytes; Phytohemagglutinins; Ultraviolet Rays | 1989 |
DNA damage and repair in normal, xeroderma pigmentosum and XP revertant cells analyzed by gel electrophoresis: excision of cyclobutane dimers from the whole genome is not necessary for cell survival.
Topics: Cell Line; Cell Survival; Cytarabine; DNA; DNA Damage; DNA Repair; DNA Replication; Dose-Response Relationship, Radiation; Fibroblasts; Humans; Hydroxyurea; Ultraviolet Rays; X-Rays; Xeroderma Pigmentosum | 1989 |
Combined therapy interferon and chemotherapy in chronic myelogenous leukemia.
Topics: Adolescent; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Child; Child, Preschool; Combined Modality Therapy; Cytarabine; Drug Evaluation; Humans; Hydroxyurea; Interferon alpha-2; Interferon Type I; Interferon-alpha; Leukemia, Myelogenous, Chronic, BCR-ABL Positive; Middle Aged; Recombinant Proteins; Remission Induction | 1989 |
Hemoglobin induction by Ara-C in human erythroleukemic cells (K562) is cell-cycle dependent.
Topics: Cell Cycle; Cell Line; Cytarabine; Heme; Hemoglobins; Humans; Hydroxyurea; Interphase; Kinetics; Leukemia, Erythroblastic, Acute | 1989 |
Mechanism of chromosome aberration induction in the mouse egg fertilized with sperm recovered from postmeiotic germ cells treated with methyl methanesulfonate.
Topics: Animals; Benzamides; Caffeine; Chromosome Aberrations; Cytarabine; Female; Hydroxyurea; Male; Meiosis; Methyl Methanesulfonate; Mice; Mice, Inbred Strains; Mutagens; Ovum; Sister Chromatid Exchange; Spermatozoa; Zygote | 1989 |
Disassembly of the mammalian metaphase chromosome into its subunits: studies with ultraviolet light and repair synthesis inhibitors.
Topics: Animals; Cell Line; Cell Transformation, Viral; Chromatids; Chromosomes; Cytarabine; Deer; DNA Repair; Hydroxyurea; Macromolecular Substances; Metaphase; Microscopy, Electron, Scanning; Ruminants; Simian virus 40; Ultraviolet Rays | 1987 |
[Deoxyribonucleic acid synthesis by rat thymus and spleen cells in vitro following hyperthermia].
Topics: Animals; Benzamides; Cytarabine; Dideoxynucleosides; DNA; Female; Hot Temperature; Hydroxyurea; Novobiocin; Rats; Spleen; Thymidine; Thymus Gland; Topoisomerase II Inhibitors | 1988 |
Comparison of histone variant synthesis in human lymphocytic leukemia cells and in normal lymphocytes.
Topics: Acetylation; Cell Cycle; Cytarabine; DNA; Histones; Humans; Hydroxyurea; Leukemia, Lymphoid; Lymphocytes; Ubiquitins | 1988 |
Analysis of the activity of DNA, RNA, and protein synthesis inhibitors on Xenopus embryo development.
Topics: Abnormalities, Drug-Induced; Animals; Cycloheximide; Cytarabine; Dactinomycin; DNA Replication; Drug Evaluation, Preclinical; Embryo, Nonmammalian; Ethidium; Female; Hydroxyurea; Protein Biosynthesis; Teratogens; Transcription, Genetic; Xenopus | 1985 |
1-beta-D-arabinofuranosylcytosine and hydroxyurea production of cytotoxic synergy with cis-diamminedichloroplatinum(II) and modification of platinum-induced DNA interstrand cross-linking.
Topics: Cell Survival; Cisplatin; Cytarabine; DNA; DNA Repair; Drug Synergism; Humans; Hydroxyurea; Tumor Cells, Cultured | 1989 |
Effects of caffeine and inhibitors of DNA synthesis on chromatid-type aberrations induced by acetaldehyde in root-tip cells.
Topics: Acetaldehyde; Caffeine; Cells, Cultured; Chromatids; Chromosome Aberrations; Cytarabine; DNA Replication; Floxuridine; Hydroxyurea; Mutagenicity Tests; Plants | 1987 |
Inhibition of thymidylate synthase in intact L1210 cells by ara-C, daunomycin, hydroxyurea and 3,4-dihydroxybenzylamine.
Topics: Animals; Cytarabine; Daunorubicin; Deoxyuridine; DNA; Dopamine; Floxuridine; Hydroxyurea; Kinetics; Leukemia L1210; Methotrexate; Thymidylate Synthase | 1987 |
Microinjected deoxynucleotides for the study of chemical inhibition of DNA synthesis.
Topics: Animals; Aphidicolin; Autoradiography; Cell Nucleus; Cells, Cultured; Cytarabine; Deoxyribonucleotides; Diterpenes; DNA Replication; Floxuridine; Hydroxyurea; Kinetics; Methotrexate; Trifluridine; Tritium | 1988 |
Scintillometric determination of unscheduled DNA synthesis in primary cultures of rat-liver cells. A hydroxylapatite batch assay.
Topics: Animals; Cells, Cultured; Cytarabine; Dimethylnitrosamine; DNA; DNA Repair; DNA Replication; Durapatite; Hydroxyapatites; Hydroxyurea; Liver; Rats; Scintillation Counting | 1985 |
Novobiocin inhibition of DNA excision repair may occur through effects on mitochondrial structure and ATP metabolism, not on repair topoisomerases.
Topics: Adenosine Triphosphate; Aphidicolin; Chromosomes; Cytarabine; Diterpenes; DNA Repair; HeLa Cells; Humans; Hydroxyurea; Mitochondria; Novobiocin; Topoisomerase I Inhibitors | 1985 |
Analysis of the structure and spatial distribution of ultraviolet-induced DNA repair patches in human cells made in the presence of inhibitors of replicative synthesis.
Topics: Cell Line; Cytarabine; DNA; DNA Repair; DNA Replication; Endonucleases; Humans; Hydroxyurea; Kinetics; Molecular Weight; Single-Strand Specific DNA and RNA Endonucleases; Ultraviolet Rays; Xeroderma Pigmentosum | 1985 |
Replication intermediates formed during initiation of DNA synthesis in methotrexate-resistant CHOC 400 cells are enriched for sequences derived from a specific, amplified restriction fragment.
Topics: Animals; Base Sequence; Cell Cycle; Cell Line; Cricetinae; Cricetulus; Cytarabine; DNA; DNA Replication; DNA Restriction Enzymes; Drug Resistance; Female; Gene Amplification; Genes; Hydroxyurea; Kinetics; Methotrexate; Ovary; Tetrahydrofolate Dehydrogenase | 1986 |
Visualization of chromatin events during DNA excision repair in XP cells: deficiency in localized but not generalized chromatin events.
Topics: Cells, Cultured; Chromatin; Cytarabine; DNA Repair; DNA Topoisomerases, Type II; Humans; Hydroxyurea; Xeroderma Pigmentosum | 1986 |
Eight drugs in one day chemotherapy for brain tumors: experience in 107 children and rationale for preradiation chemotherapy.
Topics: Antineoplastic Combined Chemotherapy Protocols; Astrocytoma; Brain Neoplasms; Child; Cisplatin; Combined Modality Therapy; Cyclophosphamide; Cytarabine; Dacarbazine; Drug Evaluation; Glioblastoma; Humans; Hydroxyurea; Lomustine; Medulloblastoma; Methylprednisolone; Neoplasm Recurrence, Local; Procarbazine; Vincristine | 1987 |
Variable effects of DNA-synthesis inhibitors upon DNA methylation in mammalian cells.
Topics: Animals; Aphidicolin; Base Sequence; Cell Line; Chromatography, High Pressure Liquid; Cricetinae; Cycloheximide; Cytarabine; Dactinomycin; Diterpenes; DNA; DNA Polymerase II; DNA Replication; Fibrosarcoma; Hydroxyurea; Methylation; Nalidixic Acid; Novobiocin | 1986 |
Proliferation-dependent reduction of sister-chromatid exchange frequency induced by mitomycin C in human lymphoblastoid cells and its suppression by inhibitors of DNA replication.
Topics: 4-Nitroquinoline-1-oxide; Cell Division; Cycloheximide; Cytarabine; Depression, Chemical; DNA Repair; DNA Replication; Ethyl Methanesulfonate; Humans; Hydroxyurea; Lymphocytes; Mitomycin; Mitomycins; Sister Chromatid Exchange | 1986 |
Adult-specific neurons in the nervous system of the moth, Manduca sexta: selective chemical ablation using hydroxyurea.
Topics: Animals; Cell Count; Cell Differentiation; Cell Division; Central Nervous System; Cytarabine; Hydroxyurea; Larva; Lepidoptera; Metamorphosis, Biological; Mitomycin; Mitomycins; Moths; Nerve Degeneration; Neuronal Plasticity; Neurons; Stem Cells | 1986 |
Estimates of the rate of ligation during excision repair of ultraviolet-damaged DNA in mammalian cells.
Topics: Adenosine Diphosphate Ribose; Animals; Aphidicolin; Benzamides; Cells, Cultured; Cricetinae; Cytarabine; Diterpenes; DNA; DNA Damage; DNA Repair; Humans; Hydroxyurea; Kinetics; Ultraviolet Rays | 1987 |
Potentiation of ara-C induced cytotoxicity by hydroxyurea in LoVo colon carcinoma cells.
Topics: Aphidicolin; Cell Line; Cell Survival; Colonic Neoplasms; Cytarabine; Diterpenes; DNA; Drug Resistance; Drug Synergism; Hydroxyurea | 1987 |
DNA repair under stress.
Topics: Aphidicolin; Cell Survival; Chromosomes; Cytarabine; Diterpenes; DNA; DNA Repair; DNA Replication; HeLa Cells; Humans; Hydroxyurea; Novobiocin; Ultraviolet Rays | 1987 |
Adenosine-diphosphoribosyltransferase inhibitors can protect against or potentiate the cytotoxicity of S-phase acting drugs.
Topics: Benzamides; Cell Survival; Cells, Cultured; Cytarabine; DNA Repair; Dose-Response Relationship, Drug; Drug Interactions; Hydroxyurea; Interphase; Poly(ADP-ribose) Polymerase Inhibitors; Thioguanine | 1988 |
[Simultaneous estimation of sister chromatid exchange and evaluation of cell cycle delay].
Topics: Animals; Caffeine; Cell Cycle; Cells, Cultured; Cricetinae; Cricetulus; Cytarabine; Hydroxyurea; Mitosis; Sister Chromatid Exchange; Thiotepa | 1988 |
IFN-gamma facilitates NGF-induced neuronal differentiation in PC12 cells.
Topics: Adrenal Gland Neoplasms; Animals; Cell Differentiation; Cell Survival; Colchicine; Cytarabine; Hydroxyurea; Interferon-gamma; Mice; Mitomycin; Mitomycins; Nerve Growth Factors; Neurons; Pheochromocytoma; Rats; Recombinant Proteins; Tumor Cells, Cultured | 1988 |
Evidence for a selective antileukemic effect of cytosine arabinoside in chronic granulocytic leukemia.
Topics: Adult; Bone Marrow; Cytarabine; Female; Humans; Hydroxyurea; Leukemia, Myeloid; Male; Philadelphia Chromosome; Pilot Projects; Remission Induction | 1988 |
Elevation of blood levels of zinc protoporphyrin by radiomimetic drugs and Friend leukemia virus.
Topics: Animals; Antineoplastic Agents; Bone Marrow Transplantation; Cyclophosphamide; Cytarabine; Erythropoiesis; Folic Acid Deficiency; Friend murine leukemia virus; Hydroxyurea; Leukemia, Experimental; Male; Methotrexate; Mice; Mice, Inbred BALB C; Mice, Inbred C3H; Porphyrins; Protoporphyrins; Radiation Dosage; Radiation Effects; Whole-Body Irradiation | 1987 |
Coordinated use of sequentially escalated cyclophosphamide and cell-cycle-specific chemotherapy (N4SE protocol) for advanced neuroblastoma: experience with 100 patients.
Topics: Age Factors; Antineoplastic Combined Chemotherapy Protocols; Bone Marrow Transplantation; Cell Cycle; Child, Preschool; Cyclophosphamide; Cytarabine; Doxorubicin; Female; Fluorouracil; Follow-Up Studies; Humans; Hydroxyurea; Infant; Male; Neuroblastoma; Time Factors; Vincristine | 1987 |
Phenotypic heterogeneity within the first complementation group of UV-sensitive mutants of Chinese hamster cell lines.
Topics: Animals; Cell Line; Cell Survival; Cricetinae; Cytarabine; DNA Damage; DNA Repair; Genetic Complementation Test; Hydroxyurea; Mutation; Phenotype; Ultraviolet Rays | 1988 |
Effects of antileukemia agents on nuclear matrix-bound DNA replication in CCRF-CEM leukemia cells.
Topics: Amsacrine; Antineoplastic Agents; Cell Nucleus; Chromatin; Cytarabine; DNA Replication; Hydroxyurea; Microscopy, Electron; Nuclear Proteins; Teniposide; Tumor Cells, Cultured | 1988 |
[Efficacy of the "8 drugs in a day" protocol in brain tumors in children].
Topics: Adolescent; Adult; Antineoplastic Combined Chemotherapy Protocols; Astrocytoma; Brain Neoplasms; Cerebellar Neoplasms; Child; Child, Preschool; Cytarabine; Cytidine Diphosphate Diglycerides; Dacarbazine; Female; Glioma; Humans; Hydroxyurea; Infant; Lomustine; Male; Medulloblastoma; Methylprednisolone; Procarbazine; Vincristine | 1988 |
Platelet clumping in Ph-negative myeloproliferative syndromes.
Topics: Adult; Aged; Blood Platelets; Cytarabine; Female; Humans; Hydroxyurea; Male; Middle Aged; Myeloproliferative Disorders; Platelet Aggregation; Platelet Count; Retrospective Studies | 1987 |
Enhancement by hemin of the sensitivity of K562 human leukemic cells to 1-beta-D-arabinofuranosylcytosine.
Topics: Aminolevulinic Acid; Butyrates; Cell Differentiation; Cell Line; Cytarabine; Daunorubicin; Deoxyguanosine; Doxorubicin; Drug Synergism; Erythropoiesis; Heme; Hemin; Humans; Hydroxyurea; Leukemia, Myeloid; Methotrexate; Thymidine; Vincristine | 1986 |
Potentiation by 1-alpha,25-dihydroxyvitamin D3 of cytotoxicity to HL-60 cells produced by cytarabine and hydroxyurea.
Topics: Calcitriol; Cell Differentiation; Cell Division; Cell Line; Cell Survival; Cytarabine; DNA, Neoplasm; Drug Synergism; Humans; Hydroxyurea; Leukemia, Myeloid, Acute | 1986 |
Histone mRNA degradation in vivo: the first detectable step occurs at or near the 3' terminus.
Topics: Base Sequence; Cell Line; Cloning, Molecular; Cytarabine; DNA Replication; Genes; Histones; Humans; Hydroxyurea; Kinetics; Leukemia, Erythroblastic, Acute; Leukemia, Myeloid; Nucleic Acid Hybridization; RNA, Messenger | 1986 |
Involvement of DNA polymerases in the repair of DNA damage by benzo[a]pyrene in cultured Chinese hamster cells.
Topics: Animals; Benzo(a)pyrene; Biotransformation; Cell Line; Cricetinae; Cricetulus; Cytarabine; DNA Damage; DNA Repair; DNA Replication; DNA-Directed DNA Polymerase; Hydroxyurea; Microsomes, Liver; Rats | 1987 |
Coadministration of methylxanthines and inhibitor compounds potentiates teratogenicity in Xenopus embryos.
Topics: Abnormalities, Drug-Induced; Animals; Caffeine; Cycloheximide; Cytarabine; Drug Synergism; Embryo, Nonmammalian; Emetine; Fluorouracil; Hydroxyurea; Theobromine; Theophylline; Xanthines; Xenopus laevis | 1987 |
Absence of DNA overreplication in Chinese hamster cells incubated with inhibitors of DNA synthesis.
Topics: Animals; Bromodeoxyuridine; Caffeine; Cells, Cultured; Centrifugation, Density Gradient; Cricetinae; Cytarabine; DNA; DNA Replication; Gene Amplification; Hydroxyurea | 1987 |
Hydroxyurea: effects on deoxyribonucleotide pool sizes correlated with effects on DNA repair in mammalian cells.
Topics: Animals; Cell Line; Cytarabine; Deoxyribonucleotides; DNA Repair; HeLa Cells; Humans; Hydroxyurea; Kinetics; Ultraviolet Rays | 1987 |
Effect of 3-aminobenzamide on the process of ultraviolet-induced DNA excision repair.
Topics: Adenosine Diphosphate Ribose; Benzamides; Cell Survival; Cytarabine; DNA Repair; DNA Replication; HeLa Cells; Humans; Hydroxyurea; Ultraviolet Rays | 1986 |
The use of metabolic inhibitors to compare the excision repair of pyrimidine dimers and nondimer DNA damages in human skin fibroblasts exposed to 254-nm and sunlamp-produced greater than 310-nm ultraviolet radiation.
Topics: Cells, Cultured; Cytarabine; DNA; DNA Repair; Dose-Response Relationship, Radiation; Fibroblasts; Humans; Hydroxyurea; Pyrimidine Dimers; Skin; Ultraviolet Rays | 1986 |
Repair pathways in mammalian cells: incision-ligation kinetics after UV, X-rays and mutagenic chemicals. Effects of 3-aminobenzamide and hydroxy urea + cytosine arabinoside.
Topics: Animals; Benzamides; Cell Survival; Cricetinae; Cytarabine; DNA; DNA Repair; Drug Combinations; Hydroxyurea; Kinetics; Mutagens; Mutation; Ultraviolet Rays; X-Rays | 1986 |
Detection of inhibitors of protein and nucleic acid synthesis using oocytes of Xenopus laevis microinjected with the herpes thymidine kinase gene.
Topics: Animals; Cycloheximide; Cytarabine; Dactinomycin; Emetine; Ethidium; Female; Genes; Hydroxyurea; Microinjections; Oocytes; Protein Biosynthesis; Puromycin; Thymidine Kinase; Transcription, Genetic; Xenopus | 1986 |
Sequential hydroxyurea-cytarabine chemotherapy for refractory non-Hodgkin's lymphoma.
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Cytarabine; Drug Evaluation; Female; Humans; Hydroxyurea; Lymphoma, Non-Hodgkin; Male; Middle Aged | 1987 |
Modulation of cytosine arabinoside (ara-C) and high-dose ara-C in acute leukemia.
Topics: Aminoacridines; Amsacrine; Antineoplastic Combined Chemotherapy Protocols; Cytarabine; Drug Resistance; Humans; Hydroxyurea; Interphase; Leukemia, Lymphoid; Leukemia, Myeloid; Leukemia, Myeloid, Acute; Thymidine | 1985 |
Effects of chemotherapy on bone marrow stroma in mice with acute myelogenous leukemia. Correlation with CFU-C and CFU-D.
Topics: Animals; Antineoplastic Agents; Bone Marrow; Bone Marrow Cells; Cytarabine; Diffusion; Doxorubicin; Fibroblasts; Granulocytes; Hematopoietic Stem Cells; Hydroxyurea; Leukemia, Experimental; Leukemia, Myeloid, Acute; Macrophages; Male; Mice; Mice, Inbred C57BL; Time Factors | 1985 |
Hypercalcaemia in the accelerated phase of chronic myelogenous leukaemia: no relationship to the phenotype of the blast cells.
Topics: Adult; Bone Marrow Examination; Cyclophosphamide; Cytarabine; Daunorubicin; Female; Humans; Hydroxyurea; Hypercalcemia; Leukemia, Myeloid; Male; Methotrexate; Middle Aged; Phenotype; Primary Myelofibrosis | 1985 |
Chronic myelogenous leukemia: a multivariate analysis of the associations of patient characteristics and therapy with survival.
Topics: Adult; Age Factors; Aged; Antineoplastic Combined Chemotherapy Protocols; Basophils; Blood Cell Count; Body Weight; Bone Marrow Cells; Busulfan; Chromosome Aberrations; Cyclophosphamide; Cytarabine; Daunorubicin; Drug Combinations; Female; Hemoglobins; Humans; Hydroxyurea; Leukemia, Myeloid; Male; Middle Aged; Philadelphia Chromosome; Prednisone; Prognosis; Risk; Vincristine | 1985 |
Mechanism of synergistic cell killing by hydroxyurea and cytosine arabinoside.
Topics: Biological Transport; Cell Line; Cell Survival; Cytarabine; Deoxycytosine Nucleotides; Deoxyribonucleotides; DNA, Neoplasm; Drug Synergism; Humans; Hydroxyurea; Leukemia, Lymphoid; Nucleic Acid Synthesis Inhibitors | 1985 |
Effect of antimetabolites and thymidine blockage on the induction of differentiation of HL-60 cells by retinoic acid or 1 alpha,25-dihydroxyvitamin D3.
Topics: Antibiotics, Antineoplastic; Aphidicolin; Calcitriol; Cell Differentiation; Cell Division; Cell Line; Cytarabine; Diterpenes; DNA Replication; Humans; Hydroxyurea; Kinetics; Leukemia, Myeloid, Acute; Tretinoin | 1985 |
Inhibition of DNA excision repair and the repair of X-ray-induced DNA damage by cytosine arabinoside and hydroxyurea.
Topics: Aphidicolin; Cytarabine; Diterpenes; DNA; DNA Damage; DNA Repair; Hydroxyurea | 1985 |
Induction of alkaline-labile sites in DNA by benzo [a]pyrene and the repair of those lesions in cultured Chinese hamster cells.
Topics: Animals; Benzo(a)pyrene; Cell Line; Cricetinae; Cricetulus; Cytarabine; DNA; DNA Repair; Fibroblasts; Hydrogen-Ion Concentration; Hydroxyurea; Lung; Ultrafiltration | 1986 |
H1 variant synthesis in proliferating and quiescent human cells.
Topics: Adult; Animals; Cell Cycle; Cells, Cultured; Cricetinae; Cricetulus; Cytarabine; DNA; Fibroblasts; HeLa Cells; Histones; Humans; Hydroxyurea; Lymphocyte Activation; Lymphocytes; Macrophages; Monocytes | 1986 |
Effect of inhibition of DNA synthesis on histone synthesis, turnover, and deposition in the rat testis.
Topics: Animals; Carcinoma, Ehrlich Tumor; Cell Nucleus; Cytarabine; DNA; Histones; Hydroxyurea; Hypophysectomy; In Vitro Techniques; Leucine; Male; Rats; Testis | 1985 |
[Residual DNA damages in irradiated HeLa cells].
Topics: Cell Survival; Cytarabine; DNA; DNA Repair; DNA Replication; HeLa Cells; Humans; Hydroxyurea; Time Factors | 1985 |
Effect of 1-beta-D-arabinofuranosyl cytosine and hydroxyurea on the repair of X-ray-induced DNA single-strand breaks in human leukemic blasts.
Topics: Cells, Cultured; Cytarabine; DNA; DNA Repair; DNA, Single-Stranded; Humans; Hydroxyurea; Leukemia; X-Rays | 1985 |
Poly (ADP-ribose) is not involved in the rejoining of DNA breaks accumulated to high levels in u.v.-irradiated HeLa cells.
Topics: Alkylating Agents; Benzamides; Cytarabine; DNA Repair; DNA Replication; DNA, Neoplasm; HeLa Cells; Humans; Hydroxyurea; Kinetics; NAD; Nucleoside Diphosphate Sugars; Poly Adenosine Diphosphate Ribose; Sulfuric Acid Esters; Ultraviolet Rays | 1985 |
Azidocytidine is a specific inhibitor of deoxyribonucleotide synthesis in 3T6 cells.
Topics: Animals; Cell Division; Cells, Cultured; Cytarabine; Cytidine; Deoxyribonucleotides; DNA Replication; Fibroblasts; Hydroxyurea; Kinetics; Mice; Phosphorylation | 1985 |
Manipulating chromosome structure and metaphase status with ultraviolet light and repair synthesis inhibitors.
Topics: Animals; Cattle; Cell Line; Cell Transformation, Viral; Cells, Cultured; Chromosomes; Cytarabine; Deer; DNA Repair; HeLa Cells; Humans; Hydroxyurea; Metaphase; Mitosis; Ultraviolet Rays | 1985 |
[Therapeutic possibilities in hypereosinophilia syndrome with Löffler's fibroplastic endomyocarditis. Efficacy of cytarabine and 6-thioguanine].
Topics: Adult; Cytarabine; Endocarditis; Eosinophilia; Female; Humans; Hydroxyurea; Male; Middle Aged; Prednisone; Thioguanine | 1985 |
Effects of hydroxyurea and thymidine derivatives on the uptake and metabolism of deoxycytidine and arabinofuranosylcytosine in log phase and contact-inhibited human diploid fibroblasts.
Topics: Arabinofuranosylcytosine Triphosphate; Cells, Cultured; Cytarabine; Deamination; Deoxycytidine; Deoxyuracil Nucleotides; Fibroblasts; Humans; Hydroxyurea; Thymidine; Thymine Nucleotides; Tritium | 1985 |
[Estimation of tumor sensitivity in vitro. II. Studies with the solid Ehrlich carcinoma of the mouse and the GW 77, a heterotransplanted human carcinoma].
Topics: Animals; Antibiotics, Antineoplastic; Autoradiography; Carcinoma; Carcinoma, Ehrlich Tumor; Colonic Neoplasms; Cricetinae; Culture Media; Cytarabine; Dactinomycin; DNA, Neoplasm; Humans; Hydroxyurea; Mice; Neoplasm Transplantation; Neoplasms, Experimental; Nucleosides; RNA, Neoplasm; Thymidine; Triaziquone; Tritium; Uridine | 1970 |
Chromatid breakage: differential effect of inhibitors of DNA synthesis during G 2 phase.
Topics: Animals; Azacitidine; Azaguanine; Cell Line; Chromatids; Chromosome Aberrations; Cricetinae; Cytarabine; Cytidine; DNA; DNA Nucleotidyltransferases; Hydroxyurea; Lung; Mitosis; Oxidoreductases; Pyridines; Ribonucleotides; Thiosemicarbazones; Triazines | 1972 |
Philadelphia-chromosome-positive preleukaemic state.
Topics: Adult; Blood Cell Count; Bone Marrow Cells; Bone Marrow Examination; Chromosome Aberrations; Cytarabine; Cytogenetics; Daunorubicin; Humans; Hydroxyurea; Leukemia, Myeloid, Acute; Male; Prednisone; Thioguanine; Vincristine | 1972 |
Use of flow microfluorometry in detailed analysis of effects of chemical agents on cell cycle progression.
Topics: Animals; Antineoplastic Agents; Autoradiography; Bleomycin; Camptothecin; Cell Division; Cell Line; Cricetinae; Cytarabine; DNA Replication; Fluorometry; Hydroxyurea; Mitosis; Thymidine; Time Factors; Tritium | 1972 |
Chemotherapy in recurrent heat and neck cancer.
Topics: Antineoplastic Agents; Bleomycin; Carcinoma, Squamous Cell; Cyclophosphamide; Cytarabine; Drug Therapy, Combination; Fluorouracil; Head; Head and Neck Neoplasms; Humans; Hydroxyurea; Injections, Intra-Arterial; Injections, Intramuscular; Methotrexate; Neoplasm Recurrence, Local; Neoplasms; Vinblastine; Vincristine | 1974 |
Flow microfluorometric analysis of cell killing with cytotoxic drugs.
Topics: Autoanalysis; Bleomycin; Cell Division; Cell Line; Cell Survival; Cytarabine; Dactinomycin; Demecolcine; DNA, Neoplasm; Histocytochemistry; Humans; Hydroxyurea; Leukemia, Myeloid; Methods; Microscopy, Fluorescence; Mitosis; Staining and Labeling; Thymidine; Time Factors; Tritium | 1974 |
[Palliative chemotherapy of bronchial cancers. Current status of the problem].
Topics: Antineoplastic Agents; Bleomycin; Bronchial Neoplasms; Cyclophosphamide; Cytarabine; Doxorubicin; Drug Therapy, Combination; Emetine; Fluorouracil; Humans; Hydroxyurea; Methotrexate; Mitomycins; Mustard Compounds; Palliative Care; Procarbazine; Thiotepa; Vinblastine | 1973 |
Malignant hepatoma in the Bantu.
Topics: Adenoma, Bile Duct; Africa, Eastern; Alanine Transaminase; Antineoplastic Agents; Aspartate Aminotransferases; Black People; Blood Proteins; Carcinoma, Hepatocellular; Clinical Enzyme Tests; Cyclophosphamide; Cytarabine; Dactinomycin; Fluorouracil; gamma-Globulins; Humans; Hydroxyurea; Liver Neoplasms; Male; Mercaptopurine; Methotrexate; Mitomycins; Nitrogen Mustard Compounds; Prednisone; Prognosis; South Africa; Vincristine | 1970 |
Treatment of the blastic phase of chronic myeloid leukaemia. A question to solve.
Topics: Adult; Antineoplastic Agents; Child; Cytarabine; Glycine; Humans; Hydroxyurea; Leukemia, Myeloid; Purines; Remission, Spontaneous; Sulfides; Valerates; Vincristine | 1972 |
[Preliminary studies on the effectiveness of the association cytosine-arabinoside, thioguanine, hydroxyureas in the treatment of blastic crisis in chronic myeloid leukemia].
Topics: Adult; Cytarabine; Drug Therapy, Combination; Female; Humans; Hydroxyurea; Leukemia, Myeloid; Male; Middle Aged; Thioguanine | 1972 |
Vaccinia virus polypeptide synthesis: sequential appearance and stability of pre- and post-replicative polypeptides.
Topics: Animals; Autoradiography; Carbon Radioisotopes; Cell Line; Cytarabine; DNA, Viral; Electrophoresis, Polyacrylamide Gel; Haplorhini; Hydroxyurea; Kidney; Methionine; Peptide Biosynthesis; Protein Hydrolysates; Sulfur Radioisotopes; Thymidine; Time Factors; Tritium; Uridine; Vaccinia virus; Virus Replication | 1974 |
Splenectomy in early chronic myeloid leukaemia: preliminary report on 37 cases.
Topics: Adolescent; Adult; Blood Cell Count; Blood Platelets; Cytarabine; Death; Drug Therapy, Combination; Hematopoiesis; Hemoperitoneum; Humans; Hydroxyurea; Leukemia, Myeloid; Leukocyte Count; Middle Aged; Organ Size; Pleural Effusion; Pneumonia; Prednisone; Pyelonephritis; Spleen; Splenectomy; Subphrenic Abscess; Thrombocytosis; Thrombophlebitis; Vincristine | 1974 |
Correlation between cell enlargement and nucleic acid and protein content of HeLa cells in unbalanced growth produced by inhibitors of DNA synthesis.
Topics: Cell Division; Culture Techniques; Cytarabine; DNA, Neoplasm; Female; Floxuridine; Growth; HeLa Cells; Humans; Hydroxyurea; Mechlorethamine; Mitomycins; Neoplasm Proteins; Nitrogen Mustard Compounds; RNA, Neoplasm; Thymidine | 1967 |
Modification of radiation response in synchronized HeLa cells by metabolic inhibitors: effects of inhibitors of DNA and protein synthesis.
Topics: Cyclohexanes; Cytarabine; DNA; Floxuridine; HeLa Cells; Hydroxyurea; In Vitro Techniques; Mitosis; Protein Biosynthesis; Puromycin; Pyridones; Radiation Effects; Thymidine | 1969 |
The reversible control of animal cell differentiation by the thymidine analog, 5-bromodeoxyuridine.
Topics: Animals; Autoradiography; Bromodeoxyuridine; Cartilage; Cell Differentiation; Chick Embryo; Culture Techniques; Cytarabine; DNA; Glycosaminoglycans; Hydroxyurea; Melanins; Muscle Proteins; Muscles; Retina; RNA; Thymidine; Time Factors; Tritium | 1970 |
Chemotherapy of metastatic malignant melanoma. Experience with 73 patients.
Topics: Adult; Aged; Antineoplastic Agents; Chlorambucil; Colchicine; Cyclophosphamide; Cytarabine; Eye Neoplasms; Female; Floxuridine; Humans; Hydroxyurea; Idoxuridine; Male; Melanoma; Melphalan; Middle Aged; Neoplasm Metastasis; Nitrogen Mustard Compounds; Nitrosourea Compounds; Skin Neoplasms; Vinblastine; Vincristine; Vulvar Neoplasms | 1971 |
Informational DNA synthesis distinguished from that of nuclear DNA by inhibitors of DNA synthesis.
Topics: Animals; Cell Nucleus; Cells, Cultured; Chick Embryo; Cytarabine; Cytoplasm; Depression, Chemical; DNA; Floxuridine; Genetic Code; Hydroxyurea; Muscles; Thymidine; Tritium | 1971 |
The mutagenicity to mammalian cells of pyrimidine nucleoside analogs.
Topics: Animals; Azaguanine; Bromodeoxyuridine; Cell Count; Cell Survival; Cells, Cultured; Clone Cells; Cricetinae; Cytarabine; DNA; Drug Resistance; Floxuridine; Hydroxyurea; Mutagens; Mutation; Pyrimidines | 1972 |
The effect of metabolic inhibitors on the production of vaccinia haemagglutinin.
Topics: Animals; Bromodeoxyuridine; Cattle; Cycloheximide; Cytarabine; Dactinomycin; DNA, Viral; Floxuridine; HeLa Cells; Hemagglutination Inhibition Tests; Hemagglutination Tests; Hemagglutination, Viral; Hemagglutinins, Viral; Humans; Hydroxyurea; Indoles; Mitomycins; Rabbits; Rifampin; Thiosemicarbazones; Vaccinia virus | 1972 |
Comparison of the effects of several inhibitors of the synthesis of nucleic acids upon the viability and progression through the cell cycle of cultured H. Ep. no. 2 cells.
Topics: Antimetabolites; Azaguanine; Carcinoma; Cell Division; Cell Line; Cell Survival; Cytarabine; DNA Replication; Dose-Response Relationship, Drug; Floxuridine; Fluorouracil; Humans; Hydroxyurea; Laryngeal Neoplasms; Mercaptopurine; Methotrexate; Mitosis; Ribonucleosides; Thioguanine; Time Factors; Tritium | 1972 |
Transformation of hamster cells in vitro by 1- -D arabinofuranosylcytosine, 5-fluorodeoxyuridine and hydroxyurea.
Topics: Animals; Cell Transformation, Neoplastic; Cricetinae; Culture Techniques; Cytarabine; Cytosine Nucleotides; DNA; Embryo, Mammalian; Floxuridine; Hydroxyurea; Neoplasm Metastasis; Tritium | 1972 |
Effects of inhibitors of DNA synthesis on the stimulation of mouse erythroid cells by erythropoietin.
Topics: Animals; Bromodeoxyuridine; Cells, Cultured; Cytarabine; DNA; Erythrocytes; Erythropoietin; Fetus; Floxuridine; Hematopoietic Stem Cells; Heme; Hemoglobins; Hydroxyurea; Iron Isotopes; Liver; Mice; Phosphorus Isotopes; RNA; Stimulation, Chemical; Tritium | 1973 |
DNA synthesis inhibition, cytotoxicity and their relationship to teratogenesis following administration of a nicotinamide antagonist, aminothiadiazole, to pregnant rats.
Topics: Abnormalities, Drug-Induced; Animals; Cleft Palate; Cytarabine; Depression, Chemical; DNA; Female; Forelimb; Heart Defects, Congenital; Hydroxyurea; Niacinamide; Pregnancy; Rats; Tail; Thiadiazoles; Thymidine; Time Factors; Tritium | 1973 |
Frozen DON cells as a source for a cell cycle assay of antitumor agents.
Topics: Alkaloids; Animals; Antibiotics, Antineoplastic; Antineoplastic Agents; Biological Assay; Camptothecin; Carbazoles; Cell Division; Cell Line; Cell Survival; Cricetinae; Cryoprotective Agents; Cytarabine; Cytological Techniques; Dactinomycin; Dimethyl Sulfoxide; Floxuridine; Formates; Freezing; Glycerol; Hydroxyurea; Lung; Mitosis; Proteins; Pyridines; Ribonucleosides; Thiosemicarbazones; Time Factors | 1974 |
Differential effects of metabolic inhibitors on cytoplasmic membrane associated and nuclear DNA.
Topics: Antimetabolites; Benzyl Compounds; Biological Transport; Bromodeoxyuridine; Carbon Radioisotopes; Cell Division; Cell Line; Cell Membrane; Cell Nucleus; Centrifugation, Density Gradient; Cytarabine; DNA; Ethidium; Floxuridine; Humans; Hydroxyurea; Lymphocytes; Rifampin; Thymidine; Time Factors | 1974 |
Effect of specific inhibitors on mitochondrial DNA replication in HeLa cells.
Topics: Carbon Radioisotopes; Centrifugation, Density Gradient; Cytarabine; Deoxyadenosines; DNA; DNA Replication; DNA, Mitochondrial; Ethidium; Floxuridine; HeLa Cells; Hydroxyurea; Thymidine; Tritium | 1974 |
[Giant cell formation and virus-specific antigens of herpesvirus hominis: information flow from the parental DNA].
Topics: Animals; Antigens; Autoradiography; Cell Line; Cytarabine; Cytopathogenic Effect, Viral; Hydroxyurea; Kidney; Mitomycins; Rabbits; Radiation Effects; RNA; Simplexvirus; Thymidine; Tritium; Ultraviolet Rays; Uridine | 1969 |
Characterization of surface antigen on cells infected by fibroma virus.
Topics: Animals; Antibody Formation; Antigen-Antibody Reactions; Antigens; Cell Line; Cell Membrane; Cell Movement; Cycloheximide; Cytarabine; DNA; DNA, Viral; Fluorescent Antibody Technique; Herpesviridae; Hydroxyurea; Hypersensitivity, Delayed; Immune Sera; Immunity; Immunity, Cellular; Kidney; Macrophages; Microscopy, Electron; Oncogenic Viruses; Papillomaviridae; Rabbits; Simian virus 40; Tumor Virus Infections; Vaccinia virus | 1970 |
Nuclear polyadenosine diphosphoribosylation during restricted macromolecular synthesis of HeLa cells.
Topics: Adenine Nucleotides; Adenosine Diphosphate; Carbon Isotopes; Cell Nucleus; Chromatin; Cycloheximide; Cytarabine; Dactinomycin; Deoxyadenosines; DNA; HeLa Cells; Hydroxyurea; NAD; Nucleoside Diphosphate Sugars; Nucleotidyltransferases; Protein Biosynthesis; Ribosomes; RNA Nucleotidyltransferases; Thymidine; Tritium; Uridine; Valine | 1972 |
Sequence of spontaneous Epstein-Barr virus activation and selective DNA synthesis in activated cells in the presence of hydroxyurea.
Topics: Adenine; Antigens, Viral; Autoradiography; Bromodeoxyuridine; Carbon Isotopes; Carcinoma; Cell Line; Cells, Cultured; Centrifugation, Density Gradient; Cytarabine; DNA, Viral; Fluorescent Antibody Technique; Herpesviridae; Herpesvirus 4, Human; Humans; Hydroxyurea; Nasopharyngeal Neoplasms; Thymidine; Thymidine Kinase; Tritium; Virus Replication | 1972 |
Enancement of uptake of Simian virus 40 by nuclei of permissive cells.
Topics: Animals; Cell Nucleus; Cells, Cultured; Culture Media; Cycloheximide; Cytarabine; Cytoplasm; Dactinomycin; DNA; Floxuridine; Haplorhini; Histones; Hydroxyurea; Kidney; Kinetics; Magnesium Sulfate; RNA; Simian virus 40; Thymidine; Tritium; Uridine | 1973 |
The repair of methyl methanesulphonate-induced lesions in the DNA of a murine lymphoma cell.
Topics: Animals; Cell Line; Centrifugation, Density Gradient; Cytarabine; Deoxycytidine; DNA Repair; DNA Replication; DNA, Single-Stranded; Hydroxyurea; Lymphocytes; Lymphoma; Mesylates; Mice; Mice, Inbred Strains; Radiation Effects; Spectrophotometry, Ultraviolet; Tritium | 1973 |
Enhanced activation of the repressed Epstein-Barr viral genome by inhibitors of DNA synthesis.
Topics: Burkitt Lymphoma; Cell Line; Cell Transformation, Neoplastic; Cytarabine; DNA; Genotype; Herpesvirus 4, Human; Hydroxyurea; Mitosis; Thymidine; Time Factors; Virus Replication | 1974 |
Regulation of herpesvirus macromolecular synthesis. I. Cascade regulation of the synthesis of three groups of viral proteins.
Topics: Amino Acids; Autoradiography; Carbon Radioisotopes; Carcinoma, Squamous Cell; Cell Line; Cells, Cultured; Cycloheximide; Cytarabine; Dactinomycin; Electrophoresis, Polyacrylamide Gel; Hydroxyurea; Laryngeal Neoplasms; Peptide Biosynthesis; Puromycin; Simplexvirus; Viral Proteins; Virus Replication | 1974 |
Regulation of herpes simplex virus-induced thymidine kinase.
Topics: Animals; Avian Sarcoma Viruses; Cell Line; Cell Transformation, Neoplastic; Cycloheximide; Cytarabine; Dactinomycin; Enzyme Induction; Hydroxyurea; Protein Biosynthesis; RNA, Messenger; RNA, Neoplasm; RNA, Viral; Sarcoma, Avian; Simplexvirus; Thymidine Kinase; Time Factors; Virus Replication | 1974 |
Inhibitors of DNA synthesis: their influence on replication and transcription of simian virus 40 DNA.
Topics: Animals; Cell Line; Centrifugation, Zonal; Chloroquine; Cytarabine; DNA Replication; Floxuridine; Haplorhini; Hydroxyurea; In Vitro Techniques; Kidney; Lucanthone; Mutation; Nucleic Acid Hybridization; Simian virus 40; Temperature; Thymidine; Time Factors; Transcription, Genetic; Tritium; Virus Replication | 1974 |
Programming of events in Epstein-Barr virus-activated cells induced by 5-iododeoxyuridine.
Topics: Antigens, Viral; Autoradiography; Burkitt Lymphoma; Cell Line; Cells, Cultured; Cytarabine; Deoxycytidine; DNA Replication; DNA, Neoplasm; DNA, Viral; Fluorescent Antibody Technique; Herpesvirus 4, Human; Humans; Hydroxyurea; Idoxuridine; Mitosis; Thymidine; Time Factors; Tritium; Viral Proteins; Virus Replication | 1974 |
Observations on the resistance of Fpstein-Barr virus DNA synthesis to hydroxyurea.
Topics: Antigens, Viral; Burkitt Lymphoma; Cell Line; Cytarabine; Depression, Chemical; DNA Replication; DNA, Viral; Fluorescent Antibody Technique; Herpesvirus 4, Human; Hybrid Cells; Hydroxyurea; Idoxuridine; Nucleic Acid Hybridization; Thymidine; Tritium | 1974 |
Isolation of herpes simplex virus DNA from virus particles and infected cells by electrophoresis in polyacrylamide gels.
Topics: Animals; Camptothecin; Carbon Radioisotopes; Cell Fractionation; Cell Line; Cell Nucleus; Centrifugation, Density Gradient; Cytarabine; Cytoplasm; DNA; DNA Replication; DNA, Viral; Electrophoresis, Polyacrylamide Gel; Haplorhini; Hydroxyurea; Kidney; Molecular Weight; Simplexvirus; Thymidine; Tritium | 1974 |
An experimental study on the significance of the bone marrow lymphocyte in haematopoietic regeneration following acute injury due to 60CO irradiation and cytotoxic drugs.
Topics: Animals; Bone Marrow; Bone Marrow Cells; Busulfan; Cobalt Radioisotopes; Cytarabine; Hematopoietic System; Hydroxyurea; Lymph Nodes; Lymphocytes; Male; Microscopy, Electron; Radiation Dosage; Radiation Injuries; Rats; Regeneration; Spleen; Thymus Gland | 1974 |
DNA synthesis in multiple myeloma cells following cell cycle-nonspecific chemotherapy.
Topics: Alkylating Agents; Autoradiography; Bone Marrow; Bone Marrow Cells; Cell Division; Cells, Cultured; Cytarabine; DNA Repair; DNA, Neoplasm; Humans; Hydroxyurea; Multiple Myeloma; Remission, Spontaneous; Thymidine; Tritium | 1974 |
Inhibition of glycoprotein and glycolipid synthesis in hamster embryo cells by cytosine arabinoside and hydroxyurea.
Topics: Animals; Carbon Radioisotopes; Cell Membrane; Cell Transformation, Neoplastic; Cells, Cultured; Cricetinae; Cytarabine; DNA; DNA Replication; Electrophoresis, Polyacrylamide Gel; Fibroblasts; Glucosamine; Glycolipids; Glycoproteins; Hydroxyurea; Thymidine; Tritium | 1974 |
Intracerebral Burkitt's lymphoma: pathology, clinical features and treatment.
Topics: Adolescent; Allopurinol; Brain Neoplasms; Burkitt Lymphoma; Child; Child, Preschool; Cyclophosphamide; Cytarabine; Daunorubicin; Dexamethasone; Female; Humans; Hydroxyurea; Male; Methotrexate; Neoplasm Metastasis; Papilledema; Prednisolone; Vincristine | 1974 |
Combination chemotherapy of adult acute nonlymphoblastic leukemia.
Topics: Acute Disease; Adolescent; Adult; Aged; Bone Marrow; Cytarabine; Drug Synergism; Female; Humans; Hydroxyurea; Leukemia; Leukemia, Myeloid; Leukemia, Myeloid, Acute; Male; Middle Aged; Nausea; Remission, Spontaneous; Thioguanine; Vomiting | 1972 |
The outlook for the adult with acute leukaemia, 1972.
Topics: Acute Disease; Adolescent; Adult; Aged; Bacterial Infections; Cytarabine; Drug Combinations; Female; Hemorrhage; Humans; Hydroxyurea; Length of Stay; Leukemia; Leukemia, Erythroblastic, Acute; Leukemia, Lymphoid; Leukemia, Myeloid, Acute; Male; Middle Aged; Patient Isolators; Prednisone; Remission, Spontaneous; Thioguanine | 1972 |
Optimism in leukemia treatment.
Topics: Acute Disease; Adult; Child; Cyclophosphamide; Cytarabine; Humans; Hydroxyurea; Leukemia; Leukemia, Lymphoid; Leukemia, Myeloid; Leukemia, Myeloid, Acute; Mercaptopurine; Methotrexate; Prednisolone; Thioguanine; Vincristine | 1973 |
[Therapy of acute leukemias].
Topics: Adrenal Cortex Hormones; Asparaginase; Cyclophosphamide; Cytarabine; Daunorubicin; Doxorubicin; Drug Therapy, Combination; Humans; Hydroxyurea; Leukemia, Lymphoid; Leukemia, Monocytic, Acute; Leukemia, Myeloid, Acute; Mercaptopurine; Methotrexate; Thioguanine; Vincristine | 1973 |
[Therapy of acute leukemia. Results of the Swiss study group for clinical cancer research (SAKK)].
Topics: Age Factors; Bone Marrow Examination; Cytarabine; Daunorubicin; Drug Therapy, Combination; Humans; Hydroxyurea; Leukemia, Myeloid, Acute; Mercaptopurine; Nitrosourea Compounds; Prednisone; Remission, Spontaneous; Thioguanine; Vincristine | 1974 |
Approaches to combination chemotherapy in rat, mouse, and hamster tumors.
Topics: Adenocarcinoma; Amides; Androstanols; Animals; Antineoplastic Agents; Cricetinae; Cyclohexanes; Cyclophosphamide; Cytarabine; Doxorubicin; Drug Therapy, Combination; Estradiol; Female; Hydroxyurea; Imidazoles; Mammary Neoplasms, Experimental; Melanoma; Melphalan; Mice; Mice, Inbred C3H; Mice, Inbred Strains; Neoplasm Transplantation; Neoplasms, Experimental; Osteosarcoma; Plasmacytoma; Progesterone; Rats; Sarcoma, Experimental; Triazenes | 1974 |
Management of priapism in patients with chronic granulocytic leukemia.
Topics: Adult; Anti-Bacterial Agents; Busulfan; Cytarabine; Diazepam; Humans; Hydroxyurea; Infusions, Parenteral; Leukemia, Myeloid; Male; Priapism; Splenomegaly | 1974 |
Intensive chemotherapy in children with acute lymphoblastic leukemia (L-2 protocol).
Topics: Administration, Oral; Adolescent; Age Factors; Antineoplastic Agents; Asparaginase; Carmustine; Chemical and Drug Induced Liver Injury; Child; Child, Preschool; Cyclophosphamide; Cytarabine; Daunorubicin; Drug Therapy, Combination; Evaluation Studies as Topic; Female; Follow-Up Studies; Humans; Hydroxyurea; Infant; Infections; Injections, Intravenous; Leukemia, Lymphoid; Male; Meningitis; Methotrexate; Prednisone; Remission, Spontaneous; Thioguanine; Vincristine | 1974 |
Proceedings: Treatment of acute leukaemia in adults.
Topics: Acute Disease; Adult; Allopurinol; Anti-Bacterial Agents; Bacterial Infections; Child; Cytarabine; Daunorubicin; Drug Therapy, Combination; Humans; Hydroxyurea; Leukemia; Leukemia, Lymphoid; Metabolic Diseases; Prednisone; Remission, Spontaneous; Thioguanine; Uric Acid; Vincristine | 1974 |
Comparative results obtained in the treatment of acute leukemia.
Topics: Antineoplastic Agents; Asparaginase; Carmustine; Cytarabine; Daunorubicin; Drug Therapy, Combination; Humans; Hydroxyurea; Leukemia; Leukemia, Lymphoid; Leukemia, Myeloid, Acute; Meningitis; Methotrexate; Prednisone; Thioguanine; Vincristine | 1973 |
Cancer chemotherapy: mechanisms of action.
Topics: Alkaloids; Alkylating Agents; Antibiotics, Antineoplastic; Antineoplastic Agents; Binding Sites; Cytarabine; Drug Synergism; Enzyme Therapy; Folic Acid Antagonists; Humans; Hydroxyurea; Leucovorin; Mechlorethamine; Mercaptopurine; Methotrexate; Mitomycins; Neoplasms; Nucleic Acids; Purines; Pyrimidines; Steroids; Thioguanine; Vinblastine; Vincristine | 1973 |
Specific increase in pyrimidine deoxynucleoside transport at the time of deoxyribonucleic acid synthesis in 3T3 mouse cells.
Topics: Animals; Biological Transport; Cell Line; Culture Media; Cycloheximide; Cytarabine; Dactinomycin; Deoxyadenosines; Deoxycytidine; Deoxyribonucleosides; DNA; Electrophoresis, Paper; Fibroblasts; Guanosine; Hydroxyurea; Kinetics; Mice; Mitomycins; Mutation; Phosphates; Phosphorus Isotopes; Thymidine; Thymidine Kinase; Time Factors; Tritium | 1973 |
The effects of inhibitors of RNA and DNA synthesis on protein synthesis and polysome levels in mouse L-cells.
Topics: Animals; Benzimidazoles; Centrifugation, Density Gradient; Cycloheximide; Cytarabine; Dactinomycin; Deoxyadenosines; DNA; DNA Replication; Dose-Response Relationship, Drug; Half-Life; Hydroxyurea; Kinetics; L Cells; Mice; Peptide Chain Elongation, Translational; Peptide Chain Initiation, Translational; Peptide Chain Termination, Translational; Phosphorus Radioisotopes; Polyribosomes; Protein Biosynthesis; Pyridines; RNA; RNA, Ribosomal; Sulfhydryl Compounds; Transcription, Genetic; Tritium | 1973 |
Immunoreactivity to antinucleoside antibodies in x-irradiated HeLa cells.
Topics: Antibodies; Antigen-Antibody Reactions; Cell Nucleus; Cytarabine; Dactinomycin; DNA, Neoplasm; DNA, Single-Stranded; Dose-Response Relationship, Radiation; Fluorescent Antibody Technique; HeLa Cells; Humans; Hydroxyurea; Immunologic Techniques; Mitosis; Nucleic Acid Denaturation; Nucleosides; Peroxidases; Radiation Effects; Thymidine; Time Factors; Tritium | 1974 |
Maturation of mitogen-activated bone marrow-derived lymphocytes in the absence of proliferation.
Topics: Animals; Antibody Formation; B-Lymphocytes; Cell Membrane; Cytarabine; DNA; Escherichia coli; Hemolytic Plaque Technique; Hydroxyurea; Immunoglobulin M; Lipopolysaccharides; Lymphocyte Activation; Lymphocytes; Mice; Mitogens; Polysaccharides, Bacterial; Thymidine; Tritium | 1974 |
Cytochemical and biochemical studies on progesterone-induced maturation in amphibian oocytes. 2. DNA synthesis.
Topics: Animals; Autoradiography; Benzyl Compounds; Bromodeoxyuridine; Cell Nucleus; Cytarabine; Cytological Techniques; Cytoplasm; Deoxyadenosines; DNA; DNA, Mitochondrial; Ethidium; Female; Hydroxyurea; Kinetics; Nucleic Acid Denaturation; Nucleic Acid Renaturation; Ovum; Photometry; Progesterone; Radiation Effects; Rana pipiens; Ribosomes; Rifampin; Thymidine; Xenopus | 1974 |
Pharmacology of 3,5-diamino-1,24-triazole (guanazole). 1. Antitumor activity of guanazole.
Topics: Amines; Animals; Antineoplastic Agents; Carcinoma 256, Walker; Cyclophosphamide; Cytarabine; Depression, Chemical; Female; Hydroxyurea; In Vitro Techniques; Leukemia L1210; Leukemia, Experimental; Lymphoma, Large B-Cell, Diffuse; Male; Mast-Cell Sarcoma; Methotrexate; Mice; Neoplasms, Experimental; Nitrosourea Compounds; Plasmacytoma; Structure-Activity Relationship; Triazoles | 1972 |
Evidence that the synchronized production of new basal bodies is not associated with DNA synthesis in Stentor coeruleus.
Topics: Animals; Autoradiography; Cilia; Ciliophora; Cytarabine; Dactinomycin; DNA; Hydroxyurea; Mitochondria; Mitomycins; Organoids; Protein Biosynthesis; Regeneration; RNA; Thymidine; Tritium | 1972 |
Effects of inhibitors of protein and nucleic acid synthesis on the expression of H-2 and Moloney leukemia virus-determined cell-surface antigens on cultured murine lymphoma cells.
Topics: Animals; Antigens; Antigens, Neoplasm; Antigens, Viral; Antineoplastic Agents; Cell Membrane; Cells, Cultured; Culture Media; Cycloheximide; Cytarabine; Dactinomycin; Histocompatibility Antigens; Hydroxyurea; Lymphoma; Mice; Mitomycins; Moloney murine leukemia virus; Neoplasm Proteins; Neoplasms, Experimental; Puromycin; RNA, Neoplasm | 1972 |
Preparation of large quantities of synchronized mammalian cells in late G1 in the pre-DNA replicative phase of the cell cycle.
Topics: Acridines; Animals; Autoradiography; Cell Line; Cells, Cultured; Cricetinae; Culture Media; Cytarabine; DNA Replication; Female; Fluorometry; Hydroxyurea; Isoleucine; Mitosis; Ovary; Thymidine; Time Factors; Tritium | 1972 |
Requirement for cell proliferation for the effects of 5-bromo-2'-deoxyuridine on cultures of chick chondrocytes.
Topics: Animals; Bromodeoxyuridine; Cartilage; Cell Division; Cells, Cultured; Chick Embryo; Chondroitin; Culture Media; Cycloheximide; Cytarabine; DNA; DNA Replication; Glucosamine; Hydroxyurea; Leucine; Sulfates; Sulfur Isotopes; Thymidine; Tritium | 1973 |
The effect of dose interval on the survival of L1210 leukemic mice treated with DNA synthesis inhibitors.
Topics: Animals; Antineoplastic Agents; Camptothecin; Cell Division; Cell Survival; Cytarabine; DNA, Neoplasm; Formates; Hydroxyurea; Leukemia L1210; Mice; Mice, Inbred C57BL; Mice, Inbred DBA; Pyridines; Thiosemicarbazones; Thymidine; Time Factors | 1973 |
Cell-kill kinetics of several S-phase-specific drugs.
Topics: Animals; Antineoplastic Agents; Camptothecin; Cell Division; Cell Line; Cell Survival; Cricetinae; Cytarabine; DNA, Neoplasm; Formates; Hydroxyurea; Kinetics; Leukemia L1210; Lung; Mice; Neoplasms, Experimental; Pyridines; Thiosemicarbazones; Time Factors | 1973 |
Relationship of temporal patterns of cell death and development to malformations in the rat limb. Possible mechanisms of teratogenesis with inhibitors of DNA synthesis.
Topics: Abnormalities, Drug-Induced; Abnormalities, Multiple; Animals; Cell Survival; Cytarabine; DNA; Ectoderm; Embryo Loss; Embryo, Mammalian; Embryonic and Fetal Development; Female; Fetal Death; Fetus; Forelimb; Hindlimb; Hydroxyurea; Limb Deformities, Congenital; Mesoderm; Necrosis; Palmitates; Pregnancy; Rats; Teratogens; Time Factors | 1973 |
The effects of chemotherapy on the morphology of solid tumours.
Topics: Antineoplastic Agents; Cell Division; Cell Nucleus; Cells; Cytarabine; Hydroxyurea; Intestinal Mucosa; Intestine, Small; Methotrexate; Microscopy, Electron; Mitosis; Neoplasms; Phagocytosis; Time Factors; Vinca Alkaloids | 1974 |
Antagonism between DNA synthesis inhibitors and protein synthesis inhibitors in mammalian cell cultures.
Topics: Animals; Antimetabolites; Cell Division; Cell Line; Cell Survival; Cells, Cultured; Cyclohexanes; Cytarabine; DNA; Formates; Hydroxyurea; Lung; Mice; Piperidones; Protein Biosynthesis; Pyridines; Thiosemicarbazones | 1974 |
Survival responses of dividing and nondividing mammalian cells after treatment with hydroxyurea, arabinosylcytosine, or adriamycin.
Topics: Animals; Cell Division; Cell Line; Cell Survival; Cells, Cultured; Cricetinae; Cytarabine; Dose-Response Relationship, Drug; Doxorubicin; Female; Hydroxyurea; Ovary; Time Factors | 1974 |
Biogenesis of poxviruses: role of A-type inclusions and host cell membranes in virus dissemination.
Topics: Animals; Autoradiography; Cell Membrane; Chick Embryo; Chickens; Culture Techniques; Cytarabine; Cytoplasm; Dactinomycin; DNA, Viral; Erythrocytes; Fluorescent Antibody Technique; Genetic Complementation Test; Genetics, Microbial; Goats; Golgi Apparatus; HeLa Cells; Hemadsorption; Hemagglutinins, Viral; Humans; Hydroxyurea; Immune Sera; Inclusion Bodies, Viral; L Cells; Microscopy, Electron; Organelle Biogenesis; Puromycin; Rabbits; Ribosomes; Rifampin; RNA, Viral; Species Specificity; Thymidine; Time Factors; Tritium; Vaccinia virus; Viral Proteins | 1971 |
A genetic approach to the study of cytotoxicity and resistance of cultured Chinese hamster cells in the presence of cytosine arabinoside.
Topics: Animals; Arginine; Carbon Isotopes; Cell Fusion; Cell Line; Cell Survival; Cricetinae; Cytarabine; DNA; Drug Resistance; Genes, Recessive; Genetic Complementation Test; Hybrid Cells; Hydroxyurea; Leucine; Lung; Protein Biosynthesis; Puromycin; Thymidine; Time Factors; Tritium | 1972 |
Use of mouse vaginal and rectal epithelium to screen antimitotic effects of systemically administered drugs.
Topics: Animals; Antineoplastic Agents; Cytarabine; Epithelial Cells; Epithelium; Female; Fluorouracil; Hydroxyurea; Mechlorethamine; Methotrexate; Mice; Mitosis; Podophyllin; Rectum; Vagina; Vinblastine | 1971 |
Effect of hydroxyurea and cytarabine on rodent epidermal cells.
Topics: Animals; Animals, Newborn; Cell Nucleus; Cytarabine; Depression, Chemical; DNA Replication; Hydroxyurea; Mice; Mitosis; Necrosis; Psoriasis; Rats; Skin; Thymidine; Tritium | 1971 |
Drugs in the treatment of leukemia.
Topics: Asparaginase; Busulfan; Chlorambucil; Cyclophosphamide; Cytarabine; Humans; Hydroxyurea; Leukemia; Leukemia, Lymphoid; Leukemia, Myeloid; Leukemia, Myeloid, Acute; Mercaptopurine; Methotrexate; Pipobroman; Prednisolone; Vincristine | 1968 |
Studies on the effects of hydroxyurea and other anticancer drugs upon pyrimidine metabolism.
Topics: Amidohydrolases; Animals; Antineoplastic Agents; Ascites; Carbon Isotopes; Cyclophosphamide; Cytarabine; Deoxyuridine; DNA; Fluorouracil; Humans; Hydroxyurea; Leukemia, Myeloid, Acute; Leukocytes; Methotrexate; Mice; Neoplasms, Experimental; Orotic Acid; Pyrimidines; Transferases; Triazines | 1969 |
The influence of post-irradiation conditions on the survival of Chinese hamster cells after gamma-irradiation.
Topics: Acridines; Animals; Caffeine; Chloramphenicol; Cricetinae; Culture Techniques; Cycloheximide; Cytarabine; Dactinomycin; DNA; Hydroxylamines; Hydroxyurea; Protein Binding; Protein Biosynthesis; Puromycin; Radiation Effects; Temperature; Thymidine | 1970 |
Studies on the mechanism of action of 1-beta-D-arabinofuranosylcytosine as an inhibitor of DNA synthesis in human leukemic leukocytes.
Topics: Animals; Binding Sites; Cytarabine; DNA Nucleotidyltransferases; DNA, Neoplasm; Humans; Hydroxyurea; In Vitro Techniques; Leukemia, Experimental; Leukocytes; Tritium; Uridine | 1969 |
Inhibition of thymidine phosphorylation and DNA and histone synthesis in Ehrlich ascites carcinoma.
Topics: Aldehydes; Animals; Arginine; Carbon Isotopes; Carcinoma, Ehrlich Tumor; Chromatography, Thin Layer; Cycloheximide; Cytarabine; Cytoplasm; DNA; Glycine; Histones; Hydroxyurea; In Vitro Techniques; Lysine; Mice; Mitomycins; Nucleotides; Orotic Acid; Puromycin; Thiosemicarbazones; Thymidine; Tritium | 1970 |
A probable role for protein synthesis in intestinal epithelial cell damage induced in vivo by cytosine arabinoside, nitrogen mustard, or X-irradiation.
Topics: Animals; Carbon Isotopes; Chemical Phenomena; Chemistry; Cycloheximide; Cytarabine; DNA; Epithelium; Hydroxyurea; Intestinal Mucosa; Intestine, Small; Ketones; Leucine; Male; Mechlorethamine; Protein Biosynthesis; Proteins; Pyrroles; Radiation Effects; Rats; RNA; Thymidine; Time Factors | 1970 |
Implications of biochemical, cytokinetic, pharmacologic, and toxicologic relationships in the design of optimal therapeutic schedules.
Topics: Animals; Antineoplastic Agents; Cyclophosphamide; Cytarabine; Dactinomycin; Daunorubicin; Disease Models, Animal; DNA, Neoplasm; Fluorouracil; Half-Life; Hydroxyurea; In Vitro Techniques; Kinetics; Leukemia L1210; Mercaptopurine; Methotrexate; Mice; Mitosis; Nitrosourea Compounds; Thiosemicarbazones | 1970 |
Intravaginal and intrarectal screening of antimitotic drugs for topical effectiveness.
Topics: Animals; Antineoplastic Agents; Colchicine; Cytarabine; Daunorubicin; Evaluation Studies as Topic; Female; Fluorouracil; Hydroxyurea; Intestinal Mucosa; Mechlorethamine; Methods; Methotrexate; Mice; Mitosis; Mucous Membrane; Nitrosourea Compounds; Podophyllin; Rectum; Vagina; Vinblastine; Vincristine | 1971 |
Viruses and renal carcinoma of Rana pipiens. VI. Interrelationships of macromolecular synthesis and infectious virus production in frog virus 3-infected BHK 21/13 cells.
Topics: Adenine; Animals; Anura; Carbon Isotopes; Culture Techniques; Cycloheximide; Cytarabine; Dactinomycin; DNA; DNA, Viral; Herpesviridae; Hydroxyurea; Idoxuridine; Inclusion Bodies, Viral; Kidney Neoplasms; Leucine; Neoplasms, Experimental; Oncogenic Viruses; Protein Biosynthesis; RNA; RNA, Viral; Thymidine; Tritium; Uridine; Viral Proteins; Virus Replication | 1968 |
Repair replication and degradation of bromouracil-substituted DNA in mammalian cells after irradiation with ultraviolet light.
Topics: Bromodeoxyuridine; Carbon Isotopes; Centrifugation, Density Gradient; Cytarabine; DNA; DNA Replication; HeLa Cells; Hydroxyurea; Radiation Effects; Radiation Genetics; Tritium; Ultraviolet Rays | 1968 |
Studies on unbalanced growth in synchronized HeLa cells.
Topics: Cycloheximide; Cytarabine; Depression, Chemical; DNA; HeLa Cells; Hydroxyurea; Mitosis; Protein Biosynthesis; RNA; Time Factors | 1968 |
Comparison of the effectiveness of S phase inhibitors in altering gene expression.
Topics: Animals; Azacitidine; Cell Line; Cell Survival; Cytarabine; Female; Genes; Hydroxyurea; Hypoxanthine Phosphoribosyltransferase; Interphase; Kinetics; Mice; Thymidine; Transcription, Genetic; X Chromosome | 1984 |
Induction of chromosome damage by Neurospora endonuclease in repair-inhibited quiescent normal human fibroblasts.
Topics: Cell Line; Chromosome Aberrations; Cytarabine; DNA Repair; Endonucleases; Fibroblasts; HeLa Cells; Humans; Hydroxyurea; Karyotyping; Kinetics; Mechlorethamine; Single-Strand Specific DNA and RNA Endonucleases | 1984 |
Cycle-dependent anticancer drug cytotoxicity in mammalian cells synchronized by centrifugal elutriation.
Topics: Animals; Antineoplastic Agents; Bleomycin; Cell Cycle; Cell Separation; Cell Survival; Cells, Cultured; Cisplatin; Cricetinae; Cricetulus; Cytarabine; Doxorubicin; Female; Hydroxyurea; Interphase; Melphalan; Mesylates; Metaphase; Ovary | 1980 |
Biochemical and cytokinetic modulation of L1210 and HL-60 cells by hydroxyurea and effect on 1-beta-D-arabinofuranosylcytosine metabolism and cytotoxicity.
Topics: Animals; Arabinofuranosylcytosine Triphosphate; Cell Line; Cell Survival; Cytarabine; Cytidine Triphosphate; DNA; Humans; Hydroxyurea; Kinetics; Leukemia L1210; Leukemia, Myeloid; Mice; RNA | 1983 |
Globin gene studies create a puzzle.
Topics: Anemia, Sickle Cell; Azacitidine; Cell Differentiation; Cytarabine; DNA; Erythropoiesis; Fetal Hemoglobin; Gene Expression Regulation; Hematopoietic Stem Cells; Humans; Hydroxyurea; Interphase; Methylation | 1984 |
An estrogen-dependent demethylation at the 5' end of the chicken vitellogenin gene is independent of DNA synthesis.
Topics: Animals; Chickens; Cytarabine; Deoxyribonuclease HpaII; DNA; DNA Replication; DNA Restriction Enzymes; Estradiol; Female; Genes; Hydroxyurea; Lipoproteins; Liver; Male; Methylation; Nucleic Acid Hybridization; RNA, Messenger; Vitellogenins | 1984 |
DNA synthesis inhibitors block protein synthesis in the human lymphocyte.
Topics: Blood Proteins; Cytarabine; DNA; Humans; Hydroxyurea; In Vitro Techniques; Leucine; Lymphocytes; Lymphokines; Mitogens; Mitomycin; Mitomycins; Phytohemagglutinins; RNA | 1984 |
Abnormal response of xeroderma pigmentosum cells to bleomycin.
Topics: Bleomycin; Cell Line; Cells, Cultured; Cytarabine; DNA; DNA Repair; DNA Replication; Fibroblasts; Humans; Hydroxyurea; Molecular Weight; Xeroderma Pigmentosum | 1984 |
Enhancement of the DNA breakage and cytotoxic effects of intercalating agents by treatment with sublethal doses of 1-beta-D-arabinofuranosylcytosine or hydroxyurea in L1210 cells.
Topics: Aminoacridines; Amsacrine; Animals; Bleomycin; Cell Survival; Cytarabine; Daunorubicin; DNA, Neoplasm; Doxorubicin; Drug Synergism; Hydroxyurea; Intercalating Agents; Leukemia L1210; Mice | 1984 |
Antimitotic drugs that enhance neuronal survival in olfactory bulb cell cultures.
Topics: Animals; Bromodeoxyuridine; Cells, Cultured; Cytarabine; Depression, Chemical; Floxuridine; Hydroxyurea; Methotrexate; Mitosis; Olfactory Bulb; Potassium; Rats; Rats, Inbred Strains; Thymidine | 1983 |
Potentiation of teratogenesis.
Topics: Animals; Antibiotics, Antineoplastic; Cytarabine; DNA; Drug Synergism; Embryo, Mammalian; Female; Floxuridine; Gestational Age; Glycine; Hydroxyurea; Pregnancy; Purines; Rats; Rats, Inbred Strains; Teratogens | 1984 |
Effect of mitomycin C and hydroxyurea on the expression of the Epstein-Barr virus cycle following P3HR-1 superinfection.
Topics: Antigens, Viral; Burkitt Lymphoma; Cell Line; Cytarabine; DNA; DNA, Viral; Herpesvirus 4, Human; Humans; Hydroxyurea; Mitomycins; Nucleic Acid Hybridization | 1980 |
Higher leukocyte nadirs with lithium carbonate after chemotherapy.
Topics: Adolescent; Adult; Child; Child, Preschool; Cyclophosphamide; Cytarabine; Female; Humans; Hydroxyurea; Leukocyte Count; Lithium; Male; Nasopharyngeal Neoplasms; Neoplasms; Neuroblastoma; Papaverine; Rhabdomyosarcoma; Sarcoma, Ewing; Teratoma; Trifluridine; Vincristine; Wilms Tumor | 1980 |
Hydroxyurea inhibits degradation of internalized epidermal growth factor in HeLa cells.
Topics: Antineoplastic Agents; Cycloheximide; Cytarabine; DNA Replication; Epidermal Growth Factor; ErbB Receptors; Floxuridine; HeLa Cells; Humans; Hydroxyurea; Kinetics; Protein Biosynthesis; Receptors, Cell Surface; Transcription, Genetic | 1982 |
Effects of DNA synthesis inhibitors on early antigen expression following primary infection or superinfection by Epstein-Barr virus.
Topics: Antigens, Viral; Burkitt Lymphoma; Cell Line; Cytarabine; DNA, Viral; Gene Expression Regulation; Genes, Viral; Herpesvirus 4, Human; Humans; Hydroxyurea; Phosphonoacetic Acid; Virus Cultivation | 1983 |
The influence of inhibitors on the repair of benzo[a]pyrene-damaged DNA in hamster tracheal epithelial cells.
Topics: Animals; Benzamides; Benzo(a)pyrene; Benzopyrenes; Carcinogens; Cell Line; Clone Cells; Cricetinae; Cytarabine; DNA Repair; DNA Replication; Epithelium; Hydroxyurea; Kinetics; Nalidixic Acid; Novobiocin; Trachea | 1984 |
Membrane and metabolic requirements for tolerance induction of neonatal B cells.
Topics: Animals; Animals, Newborn; B-Lymphocytes; Chlorpromazine; Colchicine; Cytarabine; Cytochalasins; Hydroxyurea; Immune Tolerance; Immunologic Capping; Lymphocyte Activation; Lymphocyte Depletion; Macrophages; Mice; Mice, Inbred BALB C; T-Lymphocytes; Tubercidin | 1984 |
High frequencies of chromatid aberrations produced during G2 in human lymphocytes by very low doses (0.025-0.4 Gy) of X-rays in combination with inhibitors of DNA synthesis.
Topics: Chromatids; Chromosome Aberrations; Cytarabine; Deoxyadenosines; DNA Replication; Dose-Response Relationship, Radiation; Humans; Hydroxyurea; Interphase; Lymphocytes | 1984 |
Autologous marrow transplantation for patients with chronic myelogenous leukemia (CML) in blast crisis.
Topics: Adult; Bone Marrow Transplantation; Cytarabine; Daunorubicin; Doxorubicin; Female; Freezing; Humans; Hydroxyurea; Leukemia, Myeloid; Male; Melphalan; Middle Aged; Teniposide; Thioguanine; Tissue Preservation; Transplantation, Autologous | 1984 |
Approaches to the quantitative analysis of repair through the use of inhibitors.
Topics: Animals; Arvicolinae; Cell Cycle; Cell Line; Cytarabine; DNA Repair; DNA Replication; Humans; Hydroxyurea; Kinetics; Ultraviolet Rays | 1984 |
Comparative studies of repair using inhibitors.
Topics: Animals; Arvicolinae; Bloom Syndrome; Cell Line; Cells, Cultured; Cytarabine; DNA Repair; Dose-Response Relationship, Radiation; Embryo, Mammalian; Female; Fibroblasts; Genetic Variation; Humans; Hydroxyurea; Kinetics; Pregnancy; Ultraviolet Rays; Xeroderma Pigmentosum | 1984 |
The effect of various inhibitors of DNA synthesis on the repair of DNA photoproducts.
Topics: Animals; Aphidicolin; Cell Line; Cricetinae; Cricetulus; Cytarabine; Diterpenes; DNA; DNA Polymerase II; DNA Repair; DNA Replication; Female; Hydroxyurea; Kinetics; Nalidixic Acid; Novobiocin; Ovary; Ultraviolet Rays | 1983 |
Repair-induced DNA double strand breaks after ultraviolet-light and either aphidocolin or 1-beta-D-arabinofuranosylcytosine/hydroxyurea.
Topics: Aphidicolin; Cell Line; Cytarabine; Diterpenes; DNA; DNA Polymerase II; DNA Repair; Dose-Response Relationship, Radiation; Humans; Hydroxyurea; Kinetics; Lung; Ultraviolet Rays | 1983 |
Inhibition of DNA replication coordinately reduces cellular levels of core and H1 histone mRNAs: requirement for protein synthesis.
Topics: Aphidicolin; Cycloheximide; Cytarabine; Dactinomycin; Diterpenes; DNA Polymerase II; DNA Replication; HeLa Cells; Histones; Humans; Hydroxyurea; Kinetics; Protein Biosynthesis; RNA, Messenger; Transcription, Genetic | 1984 |
The effect of inhibitors of DNA synthesis on DNA repair.
Topics: Alkylating Agents; Animals; Aphidicolin; Cytarabine; Diterpenes; DNA Polymerase II; DNA Repair; DNA Replication; DNA, Neoplasm; Hydroxyurea; Kinetics; Leukemia L1210; Mice; Ultraviolet Rays | 1984 |
Dissociation of differentiation and proliferation in the primary induction of cytolytic T lymphocytes by alloantigens.
Topics: Animals; Cell Differentiation; Cell Division; Cell Separation; Cytarabine; Cytotoxicity, Immunologic; DNA; Hydroxyurea; Isoantigens; Lymphocyte Culture Test, Mixed; Mice; Mice, Inbred C57BL; Mice, Inbred DBA; Spleen; T-Lymphocytes | 1980 |
Effects of inhibitors of DNA synthesis on spontaneous and ultraviolet light-induced sister-chromatid exchanges in Chinese hamster cells.
Topics: Animals; Cell Line; Chromatids; Cricetinae; Cricetulus; Crossing Over, Genetic; Cycloheximide; Cytarabine; Dideoxynucleotides; Hydroxyurea; Lung; Novobiocin; Sister Chromatid Exchange; Thymine Nucleotides; Ultraviolet Rays; Zinostatin | 1980 |
Relationship between chromatin structure and replication in mouse L-cells.
Topics: Animals; Chromatin; Cycloheximide; Cytarabine; DNA Replication; Floxuridine; Hydroxyurea; Isoleucine; L Cells; Methotrexate; Mice; Mitomycin; Mitomycins; Protein Biosynthesis; Structure-Activity Relationship | 1980 |
The effects of inhibitors of DNA biosynthesis on the cytotoxicity of 6-thioguanine.
Topics: Animals; Cells, Cultured; Cytarabine; DNA; DNA Replication; Floxuridine; Hydroxyurea; Interphase; Leukemia, Experimental; Mice; Thioguanine | 1981 |
Different sensitivities of granulocyte-macrophage and erythroid progenitor cells of normal human bone marrow to S-phase-specific agents.
Topics: Bone Marrow Cells; Cells, Cultured; Cytarabine; DNA Replication; Granulocytes; Hematopoietic Stem Cells; Humans; Hydroxyurea; Interphase; Macrophages | 1984 |
Visualization of chromatin events associated with repair of ultraviolet light-induced damage by premature chromosome condensation.
Topics: Cell Cycle; Chromatin; Chromosomes, Human; Cycloheximide; Cytarabine; DNA Repair; Dose-Response Relationship, Radiation; Humans; Hydroxyurea; Kinetics; Ultraviolet Rays | 1984 |
The accumulation of DNA breaks due to incision; comparative studies with various inhibitors.
Topics: Cell Cycle; Cell Line; Cells, Cultured; Cytarabine; DNA; DNA Repair; DNA Replication; DNA, Single-Stranded; Humans; Hydroxyurea; Kinetics; Skin; Ultraviolet Rays; Vidarabine; Xeroderma Pigmentosum | 1984 |
Effects of inhibitors on repair DNA synthesis in in vitro systems.
Topics: Antimetabolites; Cytarabine; Deoxyribonucleotides; DNA Repair; DNA Replication; HeLa Cells; Humans; Hydroxyurea; Interphase; Kinetics; Thymine Nucleotides; Ultraviolet Rays | 1984 |
[Radiosensitizing of experimental animal tumors using inhibitors of repair].
Topics: Animals; Cell Survival; Cells, Cultured; Cytarabine; DNA Repair; DNA, Neoplasm; Female; Hydroxyurea; Leukemia, Experimental; Mice; Radiation Tolerance; Sarcoma 37; Sarcoma, Experimental | 1984 |
[Caffeine inactivation of mammalian cells in the S phase of the mitotic cycle due to anomalous replicon initiation during the inhibition of the elongation of replicating DNA].
Topics: Animals; Caffeine; Cell Line; Cells, Cultured; Cricetinae; Cricetulus; Cytarabine; DNA; DNA Replication; Gamma Rays; Hydroxyurea; Interphase; Mitosis; Novobiocin; Replicon | 1984 |
Unscheduled DNA synthesis in cell lysate system reflecting DNA repair in vivo.
Topics: Cytarabine; Dideoxynucleosides; DNA; DNA Repair; HeLa Cells; Humans; Hydroxyurea; Thymidine; Ultraviolet Rays | 1984 |
DNA replication and repair in Tilapia cells. I. The effect of ultraviolet radiation.
Topics: Animals; Cell Division; Cell Line; Cell Survival; Cricetinae; Cytarabine; DNA; DNA Repair; DNA Replication; Female; Fishes; Hydroxyurea; Kidney; Ovary; Ultraviolet Rays | 1984 |
Effects of S-phase-specific agents on granulocyte-macrophage and erythroid progenitor cells obtained from normal individuals and from patients with chronic myelogenous leukemia.
Topics: Adult; Aged; Bone Marrow Cells; Cytarabine; Female; Granulocytes; Hematopoietic Stem Cells; Humans; Hydroxyurea; Interphase; Leukemia, Myeloid; Macrophages; Male; Middle Aged; Thymidine | 1983 |
Chronic myelomonocytic leukemia according to FAB classification: analysis of 35 cases.
Topics: Aged; Bone Marrow; Cell Transformation, Neoplastic; Cytarabine; Female; Humans; Hydroxyurea; Leukemia, Myeloid; Male; Middle Aged; Monocytes; Muramidase; Prognosis | 1984 |
Induction of terminal differentiation in human K562 erythroleukemia cells by arabinofuranosylcytosine.
Topics: Cell Differentiation; Cell Division; Cell Line; Cell Survival; Clone Cells; Cytarabine; Heme; Hemoglobins; Humans; Hydroxyurea; Kinetics; Leukemia, Myeloid, Acute | 1984 |
Phase I trial of cytarabine and hydroxyurea.
Topics: Adolescent; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Blood Cell Count; Child; Cytarabine; Drug Evaluation; Drug Resistance; Female; Gastrointestinal Diseases; Humans; Hydroxyurea; Leukemia; Lymphoma; Male; Middle Aged; Skin Diseases | 1983 |
[Possibility of an artefact in determining hematopoietic stem cell proliferation by CFUs suicide methods].
Topics: Animals; Cell Cycle; Colony-Forming Units Assay; Cytarabine; Female; Hydroxyurea; Methotrexate; Mice; Tritium | 1983 |
Effects of inhibitors of DNA strand break repair on HeLa cell radiosensitivity.
Topics: Azo Compounds; Cell Survival; Cytarabine; Diamide; DNA Repair; DNA Replication; Dose-Response Relationship, Radiation; HeLa Cells; Humans; Hydroxyurea; Kinetics | 1984 |
Do cells of continually renewing populations and those stimulated from quiescence respond similarly to HU and Ara-C?
Topics: Animals; Autoradiography; Cell Survival; Cytarabine; DNA; Hydroxyurea; Male; Mice; Mice, Inbred BALB C; Rats; Rats, Inbred Strains; Species Specificity; Tritium | 1984 |
[New method for studying the kinetics of the excision repair of DNA damages in mammalian cells].
Topics: Animals; Cell Line; Cell Survival; Cricetinae; Cricetulus; Cytarabine; DNA; DNA Repair; Gamma Rays; HeLa Cells; Humans; Hydroxyurea; Kinetics; Methods; Ultraviolet Rays | 1984 |
Cell cycle-dependent regulation of excision repair of UV damage.
Topics: Animals; Arvicolinae; Cell Cycle; Cell Survival; Cells, Cultured; Cytarabine; DNA Repair; Dose-Response Relationship, Radiation; Hydroxyurea; Kinetics; Trypsin; Ultraviolet Rays | 1982 |
Modulation of the cellular pharmacology and clinical toxicity of 1-beta-D-arabinofuranosylcytosine.
Topics: Arabinofuranosylcytosine Triphosphate; Cell Line; Cytarabine; Deoxyribonucleotides; DNA; Drug Therapy, Combination; Humans; Hydroxyurea; Leukemia; Ribonucleotide Reductases; Ribonucleotides; Thymidine | 1982 |
Inhibitors of repair DNA synthesis.
Topics: Antibiotics, Antineoplastic; Aphidicolin; Cell Line; Cytarabine; Diterpenes; DNA Repair; DNA Replication; Dose-Response Relationship, Drug; Dose-Response Relationship, Radiation; Fibroblasts; Humans; Hydroxyurea; Kinetics; Novobiocin; Ultraviolet Rays | 1982 |
Unscheduled DNA synthesis induced by N-methyl-N'-nitro-N-nitrosoguanidine in Hela cells.
Topics: Aphidicolin; Cytarabine; Dideoxynucleotides; Diterpenes; DNA; DNA Polymerase II; HeLa Cells; Humans; Hydroxyurea; Methylnitronitrosoguanidine; Nucleic Acid Synthesis Inhibitors; Thymine Nucleotides | 1982 |
Increased level of ribonucleotide reductase and associated resistance to aphidicolin in mouse FM3A cell mutants selected for simultaneous resistance to 9-beta-D-arabinofuranosyladenine and 1-beta-D-arabinofuranosylcytosine.
Topics: Animals; Aphidicolin; Cells, Cultured; Cytarabine; Diterpenes; DNA Polymerase II; Drug Resistance; Hydroxyurea; Mice; Mutation; Nucleic Acid Synthesis Inhibitors; Phenotype; Ribonucleotide Reductases; Thymidine; Vidarabine | 1982 |
Enhancement of ultraviolet-induced unscheduled DNA synthesis in HeLa cell lysate by aphidicolin in vivo.
Topics: Aphidicolin; Cytarabine; Diterpenes; DNA Polymerase II; DNA Replication; HeLa Cells; Humans; Hydroxyurea; Kinetics; Nucleic Acid Synthesis Inhibitors; Ultraviolet Rays | 1982 |
Comparison of nucleoid and alkaline sucrose gradients in the analysis of inhibitors of DNA repair in human fibroblasts.
Topics: Aphidicolin; Benzamides; Cell Line; Cytarabine; Dideoxynucleosides; Diterpenes; DNA Polymerase I; DNA Polymerase II; DNA Repair; DNA Replication; DNA, Single-Stranded; Embryology; Fibroblasts; Humans; Hydroxyurea; Molecular Weight; Nucleic Acid Synthesis Inhibitors; Skin; Thymidine; Ultraviolet Rays | 1982 |
Detection of DNA single-strand breaks during the repair of UV damage in xeroderma pigmentosum cells.
Topics: Cells, Cultured; Cytarabine; DNA; DNA Repair; DNA-Directed DNA Polymerase; Humans; Hydroxyurea; Nucleic Acid Synthesis Inhibitors; Pyrimidine Dimers; Ultraviolet Rays; Xeroderma Pigmentosum | 1983 |
Cytosine arabinoside as a suicide agent for human colony forming cells.
Topics: Bone Marrow Cells; Cells, Cultured; Cytarabine; Cytotoxicity, Immunologic; Dose-Response Relationship, Drug; Hematopoietic Stem Cells; Humans; Hydroxyurea; Neutropenia | 1983 |
Poly(ADP-ribose) metabolism in ultraviolet irradiated human fibroblasts.
Topics: Cells, Cultured; Cytarabine; DNA Repair; DNA Replication; Fibroblasts; Humans; Hydroxyurea; Infant, Newborn; Male; NAD; Nucleoside Diphosphate Sugars; Poly Adenosine Diphosphate Ribose; Skin; Ultraviolet Rays | 1983 |
U.v. induces long-lived DNA breaks in Cockayne's syndrome and cells from an immunodeficient individual (46BR): defects and disturbance in post incision steps of excision repair.
Topics: Cells, Cultured; Cockayne Syndrome; Culture Media; Cytarabine; DNA Repair; Dose-Response Relationship, Radiation; Dwarfism; Humans; Hydroxyurea; Immunologic Deficiency Syndromes; Time Factors; Ultraviolet Rays | 1983 |
Cell growth state determines susceptibility of repair DNA synthesis to inhibition by hydroxyurea and 1-beta-D-arabinofuranosylcytosine.
Topics: Animals; Cell Cycle; Cell Line; Cell Transformation, Neoplastic; Cricetinae; Cricetulus; Cytarabine; DNA Repair; DNA Replication; Drug Interactions; Fibroblasts; HeLa Cells; Hydroxyurea; Kinetics; Ultraviolet Rays | 1983 |
Sensitization of human cells by inhibitors of DNA synthesis following the action of DNA-damaging agents.
Topics: Cytarabine; DNA; DNA Replication; HeLa Cells; Humans; Hydroxyurea; Time Factors; Ultraviolet Rays | 1983 |
High rate of long-term survivals in AML treated by chemotherapy and androgenotherapy: a pilot study.
Topics: Adolescent; Adult; Antineoplastic Agents; Chemical and Drug Induced Liver Injury; Child; Child, Preschool; Cytarabine; Daunorubicin; Drug Therapy, Combination; Female; Humans; Hydroxyurea; Leukemia, Myeloid, Acute; Male; Mercaptopurine; Middle Aged; Prednisone; Stanozolol; Vincristine; Virilism | 1980 |
Potential pre-screening for therapeutic agents that induce differentiation in human myeloid leukemia cells.
Topics: Antineoplastic Agents; Bromodeoxyuridine; Cell Line; Cell Transformation, Neoplastic; Complement C3; Cytarabine; Dactinomycin; Doxorubicin; Humans; Hydroxyurea; Immunoglobulin Fc Fragments; Leukemia, Myeloid; Leukocytes; Mitomycins; Muramidase; Rosette Formation | 1980 |
[Results of complex treatment of adults with myeloblastic leukemia].
Topics: Adolescent; Adult; Aged; Antineoplastic Agents; Cyclophosphamide; Cytarabine; Daunorubicin; Drug Administration Schedule; Drug Therapy, Combination; Female; Follow-Up Studies; Humans; Hydroxyurea; Leukemia, Myeloid, Acute; Male; Mercaptopurine; Middle Aged; Prednisone; Vincristine | 1980 |
Terminal differentiation of the human promyelocytic leukemia cell line, HL-60, in the absence of cell proliferation.
Topics: Cell Cycle; Cell Differentiation; Cell Division; Cell Line; Cell Survival; Cytarabine; Dimethyl Sulfoxide; Humans; Hydroxyurea; Kinetics; Leukemia, Myeloid, Acute | 1982 |
Synergistic interaction between 1-beta-D-arabinofuranosylcytosine, thymidine, and hydroxyurea against human B cells and leukemic blasts in vitro.
Topics: Animals; B-Lymphocytes; Cells, Cultured; Cytarabine; DNA Replication; DNA, Neoplasm; Drug Synergism; Drug Therapy, Combination; Humans; Hydroxyurea; Leukemia, Experimental; Thymidine | 1981 |
Response of hypereosinophilic syndrome to 6-thioguanine and cytarabine.
Topics: Adult; Cytarabine; Eosinophilia; Heart Failure; Humans; Hydroxyurea; Male; Prednisone; Syndrome; Thioguanine | 1982 |
Regulation of thymidine kinase enzyme level in serum-stimulated mouse 3T6 fibroblasts.
Topics: Animals; Cell Cycle; Culture Media; Cytarabine; DNA Replication; Gene Expression Regulation; Growth Substances; Hydroxyurea; Mice; Thymidine; Thymidine Kinase; Transcription, Genetic | 1982 |
Role of dephosphorylation in accumulation of 1-beta-D-arabinofuranosylcytosine 5'-triphosphate in human lymphoblastic cell lines with reference to their drug sensitivity.
Topics: Arabinofuranosylcytosine Triphosphate; Arabinonucleotides; Cell Division; Cell Line; Cells, Cultured; Cytarabine; DNA, Neoplasm; Humans; Hydroxyurea; Leukemia; Lymphoma; Phosphorylation; Thymidine | 1982 |
Acute nonlymphoblastic leukemia: prognostic factors in adults with long-term follow-up.
Topics: Acute Disease; Adolescent; Adult; Age Factors; Aged; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Bacterial Vaccines; Carmustine; Cyclophosphamide; Cytarabine; Daunorubicin; Drug Therapy, Combination; Female; Follow-Up Studies; Humans; Hydroxyurea; Leukemia; Male; Methotrexate; Middle Aged; Platelet Count; Prognosis; Pseudomonas; Statistics as Topic; Thioguanine; Vincristine | 1982 |
Schedule optimization of hydroxyurea and 1-beta-D-arabinofuranosylcytosine in sarcoma 180 in vitro.
Topics: Animals; Cell Survival; Clone Cells; Cytarabine; DNA Replication; Dose-Response Relationship, Drug; Drug Administration Schedule; Flow Cytometry; Hydroxyurea; Kinetics; Mice; Sarcoma 180 | 1982 |
Effects of DNA replication inhibitors on UV excision repair in synchronised human cells.
Topics: Cytarabine; DNA Repair; DNA Replication; HeLa Cells; Humans; Hydroxyurea; Kinetics; Ultraviolet Rays | 1982 |
Uncoordinate synthesis of histone H1 in cells arrested in the G1 phase.
Topics: Animals; Cell Cycle; Cell Line; Culture Media; Cytarabine; DNA Replication; Histones; Hydroxyurea; Interphase; Mice; Plasmacytoma; Protein Biosynthesis; RNA, Messenger | 1982 |
Detection of DNA single-strand breaks produced during the repair of damage by DNA-protein cross-linking agents.
Topics: Cells, Cultured; Chromates; Cisplatin; Cytarabine; DNA Repair; DNA, Single-Stranded; Formaldehyde; Humans; Hydroxyurea | 1982 |
Change in the expression of collagen genes in dividing and nondividing chondrocytes.
Topics: Animals; Cartilage; Cell Division; Cells, Cultured; Chick Embryo; Collagen; Cytarabine; Gene Expression Regulation; Hydroxyurea | 1981 |
Volume increase in L5222 leukemic cells following chemotherapy: manifestation of leukemic cell damage.
Topics: Animals; Ascitic Fluid; Cytarabine; Daunorubicin; Fluorouracil; Hydroxyurea; Leukemia, Experimental; Rats; Vincristine | 1981 |
Sensitivity of excision repair in normal human, xeroderma pigmentosum variant and Cockayne's syndrome fibroblasts to inhibition by cytosine arabinoside.
Topics: Cockayne Syndrome; Cytarabine; DNA Repair; DNA, Single-Stranded; Dwarfism; Fibroblasts; Humans; Hydroxyurea; In Vitro Techniques; Interphase; Ultraviolet Rays; Xeroderma Pigmentosum | 1981 |
Application of arabinofuranosyl cytosine in the kinetic analysis and quantitation of DNA repair in human cells after ultraviolet irradiation.
Topics: Cells, Cultured; Cytarabine; DNA Repair; DNA Replication; Fibroblasts; Humans; Hydroxyurea; Kinetics; Skin; Ultraviolet Rays; Xeroderma Pigmentosum | 1981 |
Schedule-dependent synergism of combinations of hydroxyurea with adriamycin and 1-beta-D-arabinofuranosylcytosine with adriamycin.
Topics: Animals; Cell Line; Cell Survival; Cytarabine; Dose-Response Relationship, Drug; Doxorubicin; Drug Administration Schedule; Drug Synergism; Drug Therapy, Combination; Hydroxyurea; Mice; Sarcoma 180 | 1981 |
Increase in the cytotoxicity of 1-beta-D-arabinofuranosylcytosine due to inhibition of degradation of its triphosphate by hydroxyurea in Burkitt's lymphoma cells.
Topics: Animals; Arabinofuranosylcytosine Triphosphate; Arabinonucleotides; Burkitt Lymphoma; Cattle; Cells, Cultured; Cytarabine; Humans; Hydroxyurea | 1981 |
Clinical characteristics, DNA repair, and complementation groups in xeroderma pigmentosum patients from Egypt.
Topics: Adolescent; Cells, Cultured; Child; Consanguinity; Cytarabine; DNA Repair; DNA, Neoplasm; DNA, Single-Stranded; Egypt; Female; Genetic Complementation Test; Humans; Hydroxyurea; Infant; Male; Pedigree; Xeroderma Pigmentosum | 1980 |
DNA repair synthesis in HeLa cell lysate.
Topics: Adenosine Triphosphate; Cytarabine; Deoxyribonucleotides; DNA; DNA Repair; HeLa Cells; Humans; Hydroxyurea; Magnesium; Ultraviolet Rays | 1980 |
Synchronization of L1210 leukemia with hydroxyurea infusion and the effect of subsequent pulse dose chemotherapy.
Topics: Animals; Antineoplastic Agents; Cell Cycle; Cell Line; Cytarabine; Doxorubicin; Drug Evaluation, Preclinical; Drug Therapy, Combination; Hydroxyurea; Interphase; Leukemia L1210; Male; Methotrexate; Mice; Neoplasm Transplantation; Time Factors; Transplantation, Homologous | 1980 |
Increased activation of 1-beta-D-arabinofuranosylcytosine by hydroxyurea in L1210 cells.
Topics: Animals; Cell Line; Cytarabine; Deoxycytidine Kinase; Enzyme Activation; Hydroxyurea; Infusions, Parenteral; Leukemia L1210; Mice; Neoplasm Transplantation | 1980 |
Antagonizing effect of triphenyltin chloride on cytosine-1-beta-D-arabinofuranoside potentiation of chromosome aberrations induced by mitomycin C.
Topics: Animals; Caffeine; CHO Cells; Chromosome Aberrations; Cricetinae; Cytarabine; Drug Antagonism; Drug Synergism; G2 Phase; Hydroxyurea; Mitomycin; Mutagenesis; Organotin Compounds | 1994 |
Psychosis during interferon in eosinophilic leukaemia.
Topics: Adolescent; Adrenal Cortex Hormones; Antineoplastic Combined Chemotherapy Protocols; Combined Modality Therapy; Cyclophosphamide; Cytarabine; Delusions; Diagnosis, Differential; Epirubicin; Etoposide; Fatal Outcome; Hemibody Irradiation; Humans; Hydroxyurea; Hypereosinophilic Syndrome; Immunologic Factors; Interferon-alpha; Leukemic Infiltration; Male; Palliative Care; Pruritus; Skin; Somatoform Disorders; Splenectomy; Vasculitis; Vincristine | 1994 |
Nickel chloride inhibits the DNA repair of UV-treated but not methyl methanesulfonate-treated Chinese hamster ovary cells.
Topics: Animals; Carcinogens; Cell Survival; Centrifugation, Density Gradient; CHO Cells; Cricetinae; Cytarabine; DNA; DNA Repair; Hydroxyurea; Methyl Methanesulfonate; Nickel; Ultraviolet Rays | 1993 |
[Survival of children with primitive neuroectodermal tumors and malignant ependymomas of the central nervous system after treatment with 8 cytostatic agents in one day. A report of the Children's Cancer Group].
Topics: Antineoplastic Combined Chemotherapy Protocols; Brain Neoplasms; Carmustine; Cytarabine; Ependymoma; Follow-Up Studies; Humans; Hydroxyurea; Infant; Methylprednisolone; Neuroectodermal Tumors, Primitive; Procarbazine; Time Factors; Vincristine | 1995 |
The suitability of the micronucleus assay in human lymphocytes as a new biomarker of excision repair.
Topics: Adult; Cytarabine; DNA Repair; Evaluation Studies as Topic; Genetic Markers; Humans; Hydroxyurea; Lymphocytes; Micronucleus Tests; Mutagens; Pesticides | 1995 |
Detection of UVR-induced DNA damage in mouse epidermis in vivo using alkaline elution.
Topics: Animals; Cytarabine; DNA; DNA Damage; Epidermis; Female; Hydroxyurea; Mice; Mice, Inbred C3H; Ultraviolet Rays | 1995 |
The origin of micronuclei induced by cytosine arabinoside and its synergistic interaction with hydroxyurea in human lymphocytes.
Topics: Adult; Cytarabine; DNA Damage; DNA Repair; Drug Synergism; Humans; Hydroxyurea; In Vitro Techniques; Kinetochores; Lymphocytes; Micronuclei, Chromosome-Defective; Micronucleus Tests | 1994 |
Survival of infants with primitive neuroectodermal tumors or malignant ependymomas of the CNS treated with eight drugs in 1 day: a report from the Childrens Cancer Group.
Topics: Antineoplastic Combined Chemotherapy Protocols; Brain Neoplasms; Carmustine; Cisplatin; Cyclophosphamide; Cytarabine; Drug Administration Schedule; Ependymoma; Female; Humans; Hydroxyurea; Infant; Male; Neuroectodermal Tumors, Primitive, Peripheral; Prednisone; Procarbazine; Survival Analysis; Vincristine | 1994 |
Regulation of thymidine kinase and thymidylate synthase in intact human lymphoblast CCRF-CEM cells.
Topics: Aphidicolin; Carbon Radioisotopes; Cell Cycle; Cytarabine; Deoxycytidine; Deoxyuridine; DNA Replication; DNA, Neoplasm; Hydroxyurea; Kinetics; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Thymidine Kinase; Thymidylate Synthase; Time Factors; Tritium; Tumor Cells, Cultured | 1993 |
Down-regulation of c-myc gene is not obligatory for growth inhibition and differentiation of human myeloid leukemia cells.
Topics: Cell Differentiation; Cell Division; Cytarabine; Down-Regulation; Erythrocytes; Gene Expression Regulation, Leukemic; Genes, myc; Humans; Hydroxyurea; Interferon-alpha; Leukemia, Myeloid; Macrophages; Megakaryocytes; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured | 1993 |
Combined plateletpheresis and cytotoxic chemotherapy for symptomatic thrombocytosis in myeloproliferative disorders.
Topics: Adult; Aged; Aged, 80 and over; Busulfan; Combined Modality Therapy; Cytarabine; Drug Therapy, Combination; Female; Humans; Hydroxyurea; Male; Middle Aged; Myeloproliferative Disorders; Plateletpheresis; Remission Induction; Retrospective Studies; Thrombocytosis | 1993 |
Induction of apolipoprotein E expression during erythroid differentiation of human K562 leukemia cells.
Topics: Apolipoproteins E; Cell Differentiation; Cytarabine; Humans; Hydroxyurea; Hypercholesterolemia; Leukemia, Erythroblastic, Acute; RNA, Messenger; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured | 1993 |
A general protocol for evaluating the specific effects of DNA replication inhibitors.
Topics: Animals; Antifungal Agents; Aphidicolin; Cell Cycle; CHO Cells; Ciclopirox; Cricetinae; Cytarabine; DNA Replication; Electrophoresis, Gel, Two-Dimensional; Flow Cytometry; Genetic Techniques; Hydroxyurea; Mimosine; Pyridones; Replicon; Tetrahydrofolate Dehydrogenase | 1993 |
Bromodeoxyuridine-labelled apoptosis after treatment with antimetabolites in two murine tumours and in small intestinal crypts.
Topics: Animals; Apoptosis; Bromodeoxyuridine; Carcinoma; Cytarabine; Hydroxyurea; Intestine, Small; Male; Mice; Mice, Inbred CBA; Mitotic Index; S Phase; Sarcoma, Experimental | 1993 |
[The effect of inhibitors on induced mutagenesis].
Topics: Aphidicolin; Caffeine; Cell Line; Cytarabine; DNA Replication; G1 Phase; G2 Phase; Hydroxyurea; Mitomycin; Mutagenesis; Seeds | 1993 |
The use of gemfibrozil in a patient with chronic myelogenous leukemia to successfully manage retinoid-induced hypertriglyceridemia.
Topics: Acne Vulgaris; Adult; Combined Modality Therapy; Cytarabine; Gemfibrozil; Humans; Hydroxyurea; Hypertriglyceridemia; Immunologic Factors; Incidence; Isotretinoin; Leukemia, Myelogenous, Chronic, BCR-ABL Positive; Male | 1993 |
Detection of bcr-abl mRNA in single progenitor colonies from patients with chronic myeloid leukemia by PCR: comparison with cytogenetics and PCR from uncultured cells.
Topics: Base Sequence; Bone Marrow Transplantation; Cytarabine; Fusion Proteins, bcr-abl; Hematopoiesis; Hematopoietic Stem Cell Transplantation; Hematopoietic Stem Cells; Humans; Hydroxyurea; Interferon-alpha; Leukemia, Myelogenous, Chronic, BCR-ABL Positive; Molecular Sequence Data; Polymerase Chain Reaction; RNA, Messenger; Tumor Cells, Cultured | 1995 |
Modulation of radiation-induced chromosomal damage by inhibitors of DNA repair and flow cytometric analysis in ataxia telangiectasia cells with 'intermediate radiosensitivity'.
Topics: Aphidicolin; Ataxia Telangiectasia; Cell Cycle; Cells, Cultured; Chromosome Aberrations; Chromosomes, Human; Cytarabine; Dimethyl Sulfoxide; DNA Damage; DNA Repair; Flow Cytometry; G1 Phase; G2 Phase; Humans; Hydroxyurea; Lymphocytes; Nucleic Acid Synthesis Inhibitors; Radiation Tolerance; S Phase; Time Factors; X-Rays | 1995 |
Trisomy 21 in acute myeloid leukemia.
Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; Cytarabine; Down Syndrome; Humans; Hydroxyurea; Idarubicin; Karyotyping; Leukemia, Myelogenous, Chronic, BCR-ABL Positive; Leukemia, Myelomonocytic, Acute; Male; Mitoxantrone | 1996 |
FLANG (fludarabine + cytosine arabinoside + novantrone + G-CSF) induces partial remission in lymphoid blast transformation of Ph+chronic myelogenous leukaemia.
Topics: Antineoplastic Combined Chemotherapy Protocols; Blast Crisis; Bone Marrow; Bone Marrow Transplantation; Chromosome Aberrations; Combined Modality Therapy; Cytarabine; Disease Progression; Granulocyte Colony-Stimulating Factor; Humans; Hydroxyurea; Immunologic Factors; Interferon-alpha; Karyotyping; Leukemia, Myelogenous, Chronic, BCR-ABL Positive; Male; Mercaptopurine; Middle Aged; Mitoxantrone; Remission Induction; Vidarabine | 1996 |
Effect of modulation of the transferrin receptor on gallium-67 uptake and cytotoxicity in lymphoma cell lines.
Topics: Antineoplastic Agents; Biological Transport; Cell Cycle; Cell Division; Cell Line; Cell Survival; Cytarabine; Flow Cytometry; Gallium Radioisotopes; Gene Expression; Humans; Hydroxyurea; Lymphoma; Methotrexate; Receptors, Transferrin; Tumor Cells, Cultured; Tumor Stem Cell Assay | 1996 |
Juvenile myelomonocytic leukemia: analyses of treatment results in the EORTC Children's Leukemia Cooperative Group (CLCG).
Topics: Antineoplastic Combined Chemotherapy Protocols; Child; Child, Preschool; Combined Modality Therapy; Cytarabine; Etoposide; Female; Follow-Up Studies; Humans; Hydroxyurea; Immunologic Factors; Infant; Interferons; Isotretinoin; Leukemia, Myelomonocytic, Acute; Life Tables; Male; Mercaptopurine; Remission Induction; Retrospective Studies; Splenectomy; Transplantation Conditioning; Treatment Outcome; Whole-Body Irradiation | 1996 |
DNA damage induced by 3-chloro-4-(dichloromethyl)-5-hydroxy-2[5H]-furanone (MX) in HL-60 cells and purified DNA in vitro.
Topics: Cytarabine; DNA; DNA Damage; DNA, Single-Stranded; Electrophoresis; Filtration; Furans; Guanine; HL-60 Cells; Humans; Hydroxyurea; Mutagens; Sequence Analysis, DNA | 1997 |
Detection of MNNG-induced DNA lesions in mammalian cells; validation of comet assay against DNA unwinding technique, alkaline elution of DNA and chromosomal aberrations.
Topics: Animals; Cell Line; Child; Chromatids; Chromosome Aberrations; Cricetinae; Cytarabine; DNA; DNA Damage; DNA Repair; Dose-Response Relationship, Drug; Humans; Hydroxyurea; Male; Metaphase; Methylnitronitrosoguanidine; Mutagenesis; Mutagenicity Tests; Mutagens; Reproducibility of Results; Skin; Tumor Cells, Cultured | 1997 |
DNA damage, gadd153 expression, and cytotoxicity in plateau-phase renal proximal tubular epithelial cells treated with a quinol thioether.
Topics: Animals; Aurintricarboxylic Acid; Benzamides; Catalase; CCAAT-Enhancer-Binding Proteins; Cell Line; Cell Survival; Chelating Agents; Cytarabine; DNA Damage; DNA Repair; DNA-Binding Proteins; Endodeoxyribonucleases; Enzyme Activation; Enzyme Inhibitors; Gene Expression Regulation; Glutathione; Histones; Hydrogen Peroxide; Hydroquinones; Hydroxyl Radical; Hydroxyurea; Kidney Tubules, Proximal; Poly(ADP-ribose) Polymerases; Reactive Oxygen Species; Stress, Physiological; Swine; Transcription Factor CHOP; Transcription Factors | 1997 |
Optimizing treatment for chronic myeloid leukemia.
Topics: Antineoplastic Combined Chemotherapy Protocols; Cytarabine; Humans; Hydroxyurea; Interferon alpha-2; Interferon-alpha; Leukemia, Myelogenous, Chronic, BCR-ABL Positive; Recombinant Proteins | 1997 |
Apoptosis-resistant phenotype selected by alternating exposure to camptothecin and etoposide.
Topics: Antineoplastic Agents; Apoptosis; Arabinofuranosylcytosine Triphosphate; ATP Binding Cassette Transporter, Subfamily B, Member 1; bcl-X Protein; Calcimycin; Camptothecin; Clone Cells; Cycloheximide; Cytarabine; DNA Fragmentation; Drug Resistance, Neoplasm; Etoposide; HL-60 Cells; Humans; Hydroxyurea; Kinetics; Nucleosomes; Phenotype; Proto-Oncogene Proteins c-bcl-2; Ultraviolet Rays | 1997 |
Arsenite retards DNA break rejoining by inhibiting DNA ligation.
Topics: Animals; Arsenites; Cell Survival; CHO Cells; Cricetinae; Cytarabine; DNA; DNA Damage; DNA Repair; Hydroxyurea; Kinetics; Methyl Methanesulfonate; Mutagenesis; Mutagens; Oligodeoxyribonucleotides; Poly A; Polydeoxyribonucleotides; Time Factors | 1997 |
Salvage therapy for relapsed or refractory childhood acute lymphocytic leukemia by alternative administration a lymphoid- and myeloid-directed chemotherapeutic regimen consisting of dual modulation of ara-C, hydroxyurea, and etoposide.
Topics: Antineoplastic Combined Chemotherapy Protocols; Asparaginase; Bone Marrow Transplantation; Child; Combined Modality Therapy; Cyclophosphamide; Cytarabine; Dexamethasone; Drug Administration Schedule; Drug Evaluation; Etoposide; Female; Fever; Gastrointestinal Diseases; Humans; Hydrocortisone; Hydroxyurea; Leucovorin; Male; Methotrexate; Mitoxantrone; Pilot Projects; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Recurrence; Remission Induction; Salvage Therapy; Treatment Outcome | 1997 |
NADH dehydrogenase deficiency in an apoptosis-resistant mutant isolated from a human HL-60 leukemia cell line.
Topics: Antineoplastic Agents; Apoptosis; Calcimycin; Camptothecin; Cell Division; Clone Cells; Cloning, Molecular; Cytarabine; Deoxyglucose; Etoposide; Glucose; HL-60 Cells; Humans; Hydroxyurea; Macromolecular Substances; Mitochondria; Mutagenesis; NADH Dehydrogenase; Transcription, Genetic; Ultraviolet Rays | 1997 |
DNA damage in breast epithelial cells: detection by the single-cell gel (comet) assay and induction by human mammary lipid extracts.
Topics: Adult; Breast; Cells, Cultured; Cytarabine; DNA Damage; DNA Repair; Epithelial Cells; Female; Humans; Hydroxyurea; Lipids; Middle Aged | 1997 |
Fewer chromosome aberrations and earlier apoptosis induced by DNA synthesis inhibitors, a topoisomerase II inhibitor or alkylating agents in human cells with normal compared with mutant p53.
Topics: Alkylating Agents; Antineoplastic Agents; Aphidicolin; Apoptosis; B-Lymphocytes; Cell Division; Cell Line; Chromosome Aberrations; Cytarabine; DNA Replication; Etoposide; Humans; Hydroxyurea; Methotrexate; Mutagenesis; Nucleic Acid Synthesis Inhibitors; Radiation, Ionizing; Topoisomerase II Inhibitors; Tumor Suppressor Protein p53 | 1998 |
Different effects of an oligonucleotide uptake stimulating protein on leukemic cells in their primitive and differentiated state.
Topics: Biological Transport; Cell Differentiation; Cell Division; Cytarabine; DNA-Binding Proteins; Fungal Proteins; Gene Transfer Techniques; Granulocytes; HL-60 Cells; Humans; Hydroxyurea; Leukemia; Leukocytes, Mononuclear; Oligodeoxyribonucleotides; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured | 1998 |
Methods for registration of spontaneous DNA instability in mammalian cells.
Topics: Benzimidazoles; Bromodeoxyuridine; Cell Cycle; Cells, Cultured; Chromosome Breakage; Cytarabine; DNA; DNA Repair; Drug Stability; Fluorescent Dyes; HeLa Cells; Humans; Hydroxyurea; Lymphocytes; Photolysis; Ultraviolet Rays | 1998 |
DNA damage induces p21 protein expression by inhibiting ubiquitination in ML-1 cells.
Topics: Acetylcysteine; Cell Nucleus; Cyclin-Dependent Kinase Inhibitor p21; Cyclins; Cysteine Proteinase Inhibitors; Cytarabine; Deferoxamine; DNA Damage; Etoposide; Gene Expression Regulation; Hydroxyurea; Polyribosomes; RNA, Messenger; Tumor Cells, Cultured; Ubiquitins | 1998 |
Interferon-alpha for the treatment of elderly patients with chronic myeloid leukaemia.
Topics: Adolescent; Adult; Aged; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Child; Child, Preschool; Cytarabine; Humans; Hydroxyurea; Interferon-alpha; Leukemia, Myelogenous, Chronic, BCR-ABL Positive; Middle Aged; Retrospective Studies; Survival Rate | 1998 |
Control of the human cell cycle by a bacterial protein, gapstatin.
Topics: Aggregatibacter actinomycetemcomitans; Animals; Bacterial Proteins; Cell Cycle; Cell Cycle Proteins; Cells, Cultured; Cytarabine; Demecolcine; DNA; Fibroblasts; Humans; Hydroxyurea; Mice; Nucleic Acid Synthesis Inhibitors; Protein Biosynthesis; Receptors, Cell Surface; RNA; Time Factors | 1998 |
Genotoxicity of human milk extracts and detection of DNA damage in exfoliated cells recovered from breast milk.
Topics: Breast; Breast Neoplasms; Cells, Cultured; Cytarabine; DNA Damage; Dose-Response Relationship, Drug; Epithelial Cells; Female; Humans; Hydroxyurea; Micronucleus Tests; Milk, Human; Mutagenicity Tests; Mutagens; Pilot Projects; Ribosomal Protein S9; Ribosomal Proteins; Salmonella typhimurium; Time Factors | 1999 |
Persisting bone marrow aplasia following interferon-alpha combined with ara-C for chronic myelogenous leukemia.
Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; Bone Marrow; Cytarabine; Dose-Response Relationship, Drug; Humans; Hydroxyurea; Interferon-alpha; Leukemia, Myeloid, Chronic-Phase; Male; Pancytopenia | 1999 |
[Interferon-alpha in the treatment of chronic myeloid leukemia].
Topics: Adult; Age Factors; Aged; Antimetabolites, Antineoplastic; Antineoplastic Agents; Antineoplastic Agents, Alkylating; Bone Marrow Transplantation; Busulfan; Cause of Death; Cytarabine; Humans; Hydroxyurea; Interferon-alpha; Leukemia, Myelogenous, Chronic, BCR-ABL Positive; Middle Aged; Philadelphia Chromosome | 1999 |
The DNA repair inhibitors hydroxyurea and cytosine arabinoside enhance the sensitivity of the alkaline single-cell gel electrophoresis ('comet') assay in metabolically-competent MCL-5 cells.
Topics: Amines; Benzene; Bleomycin; Cell Line; Cell Survival; Chlorides; Chromates; Chromium Compounds; Cisplatin; Cytarabine; Diethylstilbestrol; DNA; DNA Damage; DNA Repair; Dose-Response Relationship, Drug; Electrophoresis, Agar Gel; Heterocyclic Compounds; Hexachlorocyclohexane; Humans; Hydroxyurea; Methylnitronitrosoguanidine; Mutagenicity Tests; Nitro Compounds; Nucleic Acid Synthesis Inhibitors; Polycyclic Aromatic Hydrocarbons; Radiation, Ionizing; Reproducibility of Results; Sensitivity and Specificity; Sodium Compounds; Sucrose | 1999 |
Serum beta-2 microglobulin levels are a significant prognostic factor in Philadelphia chromosome-positive chronic myelogenous leukemia.
Topics: Aged; Antineoplastic Agents; beta 2-Microglobulin; Biomarkers, Tumor; Cytarabine; Disease-Free Survival; Humans; Hydroxyurea; Interferon Type I; Interferon-alpha; Interferon-gamma; Leukemia, Myelogenous, Chronic, BCR-ABL Positive; Middle Aged; Prognosis; Recombinant Proteins; Survival Rate; Time Factors | 2000 |
Use of single cell gel electrophoresis (comet assay) modifications for analysis of DNA damage.
Topics: Animals; Cell Line; Comet Assay; Cricetinae; Cricetulus; Cytarabine; Deoxyribonuclease (Pyrimidine Dimer); DNA Damage; DNA Repair; DNA-Formamidopyrimidine Glycosylase; DNA, Single-Stranded; Endodeoxyribonucleases; Escherichia coli Proteins; Hydrogen Peroxide; Hydroxyurea; Methylnitronitrosoguanidine; N-Glycosyl Hydrolases | 1999 |
Enhancement of antiherpetic activity of cytarabine by hydroxyurea in human embryonic skin-muscle fibroblasts.
Topics: Antiviral Agents; Cells, Cultured; Cytarabine; Drug Synergism; Embryo, Mammalian; Fibroblasts; Herpesvirus 1, Human; Herpesvirus 2, Human; Humans; Hydroxyurea; Muscles; Skin | 2000 |
STAT5 activation contributes to growth and viability in Bcr/Abl-transformed cells.
Topics: Animals; Anti-Bacterial Agents; Antimetabolites, Antineoplastic; Cell Cycle; Cell Division; Cell Line; Cell Line, Transformed; Cell Survival; Cytarabine; DNA-Binding Proteins; DNA, Complementary; Dose-Response Relationship, Drug; Doxycycline; Enzyme Inhibitors; Fusion Proteins, bcr-abl; Genes, Reporter; Hydroxyurea; Mice; Milk Proteins; Mutation; Phosphorylation; Promoter Regions, Genetic; STAT5 Transcription Factor; Time Factors; Trans-Activators; Tyrosine | 2000 |
In vitro cytotoxic effects of fludarabine (2-F-ara-A) in combination with commonly used antileukemic agents by isobologram analysis.
Topics: Antimetabolites, Antineoplastic; Antineoplastic Agents; Cell Survival; Cyclophosphamide; Cytarabine; Dose-Response Relationship, Drug; Doxorubicin; Drug Screening Assays, Antitumor; Drug Synergism; Etoposide; Humans; Hydroxyurea; Leukemia-Lymphoma, Adult T-Cell; Leukemia, Hairy Cell; Leukemia, Lymphocytic, Chronic, B-Cell; Methotrexate; Neoplastic Stem Cells; Tumor Cells, Cultured; Vidarabine; Vidarabine Phosphate; Vincristine | 2000 |
Trisomy 14 with thrombocytosis and monocytosis.
Topics: Aclarubicin; Aged; Antibiotics, Antineoplastic; Antimetabolites, Antineoplastic; Antineoplastic Agents; Chromosomes, Human, Pair 14; Cytarabine; Humans; Hydroxyurea; Leukemia, Myelomonocytic, Chronic; Leukocyte Disorders; Male; Monocytes; Quality of Life; Thrombocytosis; Trisomy | 2000 |
[Hematologic and cytogenetic response to treatment in patients with chronic myeloid leukemia].
Topics: Adolescent; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Cytarabine; Female; Humans; Hydroxyurea; Interferon-alpha; Leukemia, Myelogenous, Chronic, BCR-ABL Positive; Male; Middle Aged; Philadelphia Chromosome | 2000 |
Efficacy of STI571, an abl tyrosine kinase inhibitor, in conjunction with other antileukemic agents against bcr-abl-positive cells.
Topics: Antineoplastic Agents; Benzamides; Blast Crisis; Cell Division; Cell Survival; Cytarabine; Daunorubicin; Fusion Proteins, bcr-abl; Granulocyte-Macrophage Colony-Stimulating Factor; Humans; Hydroxyurea; Imatinib Mesylate; Interleukin-3; Leukemia, Megakaryoblastic, Acute; Piperazines; Protein-Tyrosine Kinases; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-bcr; Pyrimidines; Stem Cell Factor; Transfection; Tumor Cells, Cultured; Tumor Stem Cell Assay | 2000 |
JP-8 jet fuel-induced DNA damage in H4IIE rat hepatoma cells.
Topics: Animals; Apoptosis; Carcinoma, Hepatocellular; Cell Survival; Comet Assay; Cytarabine; DNA Damage; DNA Repair; Dose-Response Relationship, Drug; Hydrocarbons; Hydroxyurea; Kerosene; Mutagenicity Tests; Nucleic Acid Synthesis Inhibitors; Rats; Tumor Cells, Cultured | 2001 |
Cell cycle-related changes in regulatory volume decrease and volume-sensitive chloride conductance in mouse fibroblasts.
Topics: Animals; Aphidicolin; Cell Cycle; Cell Division; Cell Line; Cell Size; Chlorides; Culture Media, Serum-Free; Cytarabine; Electric Conductivity; Enzyme Inhibitors; Fibroblasts; Hydroxyurea; Ion Transport; Lovastatin; Mice; Mimosine; Osmotic Pressure; Paclitaxel; Patch-Clamp Techniques | 2001 |
In vitro cytotoxic effects of a tyrosine kinase inhibitor STI571 in combination with commonly used antileukemic agents.
Topics: Antineoplastic Agents; Apoptosis; Benzamides; Cytarabine; Dose-Response Relationship, Drug; Drug Interactions; Drug Resistance, Neoplasm; Drug Screening Assays, Antitumor; Drug Synergism; Enzyme Inhibitors; Fusion Proteins, bcr-abl; Harringtonines; Homoharringtonine; Humans; Hydroxyurea; Imatinib Mesylate; Interferon-alpha; Leukemia; Leukemia, Myelogenous, Chronic, BCR-ABL Positive; Methotrexate; Microbial Sensitivity Tests; Neoplasm Proteins; Neoplasms; Piperazines; Pyrimidines; Tumor Cells, Cultured; Vincristine | 2001 |
ATR-mediated checkpoint pathways regulate phosphorylation and activation of human Chk1.
Topics: Adenoviridae; Amino Acid Motifs; Antineoplastic Agents; Ataxia Telangiectasia Mutated Proteins; Caffeine; Cell Cycle; Cell Cycle Proteins; Cell Line; Checkpoint Kinase 1; Cisplatin; Cytarabine; DNA Damage; Enzyme Activation; Etoposide; Genes, Reporter; Humans; Hydroxyurea; Immunoblotting; Nucleic Acid Synthesis Inhibitors; Phosphodiesterase Inhibitors; Phosphoric Monoester Hydrolases; Phosphorylation; Phosphoserine; Protein Kinases; Protein Serine-Threonine Kinases; Recombinant Fusion Proteins | 2001 |
Molecular remission following high-dose hydroxyurea and fludarabine plus cytarabine in a patient with simultaneous acute myeloid leukemia and low-grade lymphoma.
Topics: Acute Disease; Antineoplastic Combined Chemotherapy Protocols; Cytarabine; Humans; Hydroxyurea; Leukemia, Myeloid; Lymphoma; Neoplasms, Multiple Primary; Remission Induction; Vidarabine | 2001 |
Accumulation of gamma-globin mRNA and induction of erythroid differentiation after treatment of human leukaemic K562 cells with tallimustine.
Topics: Apoptosis; Blotting, Northern; Cell Differentiation; Cell Division; Cytarabine; Distamycins; DNA-Binding Proteins; Erythrocytes; Fetal Hemoglobin; Globins; Hematopoietic Stem Cells; Hemoglobins; Humans; Hydroxyurea; K562 Cells; Nitrogen Mustard Compounds; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger | 2001 |
Multiple herpes simplex virus infections with various resistance patterns in a matched unrelated donor transplant recipient.
Topics: Acyclovir; Antineoplastic Agents, Alkylating; Antiviral Agents; Bone Marrow Transplantation; Cidofovir; Combined Modality Therapy; Cyclosporine; Cytarabine; Cytomegalovirus Infections; Cytosine; Drug Resistance, Viral; Fatal Outcome; Foscarnet; Graft vs Host Disease; Herpes Genitalis; Herpes Simplex; Humans; Hydroxyurea; Immunocompromised Host; Immunosuppressive Agents; Interferons; Leukemia, Myelogenous, Chronic, BCR-ABL Positive; Male; Methotrexate; Middle Aged; Organophosphonates; Organophosphorus Compounds; Simplexvirus; Transplantation Conditioning; Whole-Body Irradiation | 2001 |
Collection of Philadelphia-negative stem cells using recombinant human granulocyte colony-stimulating factor in chronic myeloid leukemia patients treated with alpha-interferon.
Topics: Adolescent; Adult; Antineoplastic Combined Chemotherapy Protocols; Blood Cell Count; Blood Component Removal; Bone Marrow Purging; Busulfan; Cytarabine; Feasibility Studies; Female; Filgrastim; Granulocyte Colony-Stimulating Factor; Hematopoietic Stem Cell Mobilization; Hematopoietic Stem Cell Transplantation; Hematopoietic Stem Cells; Humans; Hydroxyurea; Immunologic Factors; Interferons; Leukemia, Myelogenous, Chronic, BCR-ABL Positive; Leukocytosis; Male; Middle Aged; Neoplastic Cells, Circulating; Pain; Philadelphia Chromosome; Recombinant Proteins; Remission Induction; Safety; Transplantation, Autologous; Treatment Outcome | 2002 |
Homologous recombination induced by replication inhibition, is stimulated by expression of mutant p53.
Topics: Animals; Aphidicolin; Cell Cycle; Cell Line; Ciclopirox; Cytarabine; DNA Replication; Gene Expression; Genes, p53; Hydroxyurea; Mice; Mimosine; Mutation; Pyridones; Recombination, Genetic; Tumor Suppressor Protein p53 | 2002 |
Telomerase overexpression in K562 leukemia cells protects against apoptosis by serum deprivation and double-stranded DNA break inducing agents, but not against DNA synthesis inhibitors.
Topics: Antineoplastic Agents; Apoptosis; Culture Media, Serum-Free; Cytarabine; DNA Damage; DNA Replication; Etoposide; Humans; Hydroxyurea; K562 Cells; Nucleic Acid Synthesis Inhibitors; Telomerase; Telomere; Transfection | 2002 |
Autologous peripheral blood progenitor cell transplantation with <2 x 10(6) CD34(+)/kg: an analysis of variables concerning mobilisation and engraftment.
Topics: Adolescent; Adult; Aged; Antigens, CD34; Antineoplastic Combined Chemotherapy Protocols; Blood Cell Count; Caspase 14; Caspases; Cerebral Hemorrhage; Cohort Studies; Combined Modality Therapy; Cyclophosphamide; Cytarabine; Erythropoietin; Etoposide; Female; Graft Survival; Granulocyte Colony-Stimulating Factor; Hematologic Neoplasms; Hematopoietic Stem Cell Mobilization; Hematopoietic Stem Cell Transplantation; Humans; Hydroxyurea; Infections; Leukapheresis; Life Tables; Male; Middle Aged; Neoplasms; Proportional Hazards Models; Transplantation Conditioning; Transplantation, Autologous | 2000 |
Enhancement of DNA ligase I level by gemcitabine in human cancer cells.
Topics: Antimetabolites, Antineoplastic; Blotting, Western; Cell Cycle; Cytarabine; Deoxycytidine; DNA Ligase ATP; DNA Ligases; Dose-Response Relationship, Drug; Enzyme Activation; Fluorouracil; Gemcitabine; Humans; Hydroxyurea; Tumor Cells, Cultured | 2002 |
Response of idiopathic hypereosinophilic syndrome to treatment with imatinib mesylate.
Topics: Alkylating Agents; Antimetabolites; Benzamides; Bone and Bones; Busulfan; Cladribine; Combined Modality Therapy; Consciousness Disorders; Cytarabine; Drug Resistance, Multiple; Enzyme Inhibitors; Fatal Outcome; Humans; Hydroxyurea; Hypereosinophilic Syndrome; Imatinib Mesylate; Immunosuppressive Agents; Indomethacin; Infarction; Male; Middle Aged; Mitral Valve Stenosis; Pancytopenia; Piperazines; Protein-Tyrosine Kinases; Pyrimidines; Splenectomy | 2002 |
A method for assaying the sensitivity of Drosophila replication checkpoint mutants to anti-cancer and DNA-damaging drugs.
Topics: Animals; Antineoplastic Agents; Cell Cycle; Cell Cycle Proteins; Checkpoint Kinase 1; Cisplatin; Cytarabine; DNA Damage; DNA Replication; DNA-Binding Proteins; Drosophila; Drosophila Proteins; Female; Genes, Insect; Hydroxyurea; Male; Methyl Methanesulfonate; Mutation; Nuclear Proteins; Paraquat; Protein Kinases; Protein Serine-Threonine Kinases; Protein-Tyrosine Kinases; Schizosaccharomyces pombe Proteins | 2002 |
Microcystin-LR induces oxidative DNA damage in human hepatoma cell line HepG2.
Topics: Bacterial Toxins; Carcinoma, Hepatocellular; Cyanobacteria; Cytarabine; Dimethyl Sulfoxide; DNA Damage; Dose-Response Relationship, Drug; Humans; Hydroxyurea; Liver Neoplasms; Marine Toxins; Microcystins; Oxidation-Reduction; Peptides, Cyclic; Tumor Cells, Cultured | 2003 |
[Chronic myeloid leukemia--case report].
Topics: Adult; Antineoplastic Agents; Benzamides; Bone Marrow Transplantation; Cytarabine; Humans; Hydroxyurea; Imatinib Mesylate; Interferon-alpha; Leukemia, Myelogenous, Chronic, BCR-ABL Positive; Lymphocyte Transfusion; Male; Piperazines; Prognosis; Pyrimidines; Remission Induction | 2002 |
Double minutes containing amplified bcr-abl fusion gene in a case of chronic myeloid leukemia treated by imatinib.
Topics: Aneuploidy; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Benzamides; Blast Crisis; Chromosome Aberrations; Chromosome Painting; Combined Modality Therapy; Cytarabine; Drug Resistance, Neoplasm; Enzyme Inhibitors; Fatal Outcome; Fusion Proteins, bcr-abl; Gene Amplification; Humans; Hydroxyurea; Imatinib Mesylate; Interferon-alpha; Karyotyping; Leukemia, Myelogenous, Chronic, BCR-ABL Positive; Male; Middle Aged; Neoplasm Proteins; Peripheral Blood Stem Cell Transplantation; Philadelphia Chromosome; Piperazines; Pyrimidines; Transplantation, Autologous | 2003 |
[Chronic myeloid leukemia. What's in the future therapy in Black Africa?].
Topics: Adult; Age Factors; Antimetabolites, Antineoplastic; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Congo; Cytarabine; Female; Follow-Up Studies; Humans; Hydroxyurea; Interferon alpha-2; Interferon-alpha; Leukemia, Myelogenous, Chronic, BCR-ABL Positive; Male; Middle Aged; Prognosis; Recombinant Proteins; Retrospective Studies; Sex Factors; Socioeconomic Factors; Time Factors | 2003 |
Analysis of single nucleotide polymorphism C3435T of the multidrug resistance gene MDR1 in acute lymphoblastic leukemia.
Topics: Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Asparaginase; Case-Control Studies; Cyclophosphamide; Cytarabine; Daunorubicin; Drug Resistance, Multiple; Drug Resistance, Neoplasm; Female; Genes, MDR; Humans; Hydroxyurea; Male; Mercaptopurine; Methotrexate; Polymorphism, Single Nucleotide; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Prednisone; Prognosis; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization; Tumor Cells, Cultured; Vincristine | 2003 |
Accumulation of gamma-globin mRNA in human erythroid cells treated with angelicin.
Topics: Cell Differentiation; Cell Division; Chromatography, High Pressure Liquid; Cisplatin; Cytarabine; Erythrocytes; Erythroid Precursor Cells; Fetal Hemoglobin; Furocoumarins; Gene Expression; Globins; Glyceraldehyde-3-Phosphate Dehydrogenases; Humans; Hydroxyurea; K562 Cells; Kinetics; Plicamycin; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger | 2003 |
Fe(II)-induced DNA damage in alpha-synuclein-transfected human dopaminergic BE(2)-M17 neuroblastoma cells: detection by the Comet assay.
Topics: alpha-Synuclein; Amino Acid Substitution; Cell Line, Tumor; Comet Assay; Cytarabine; DNA; DNA Damage; DNA Repair; Dopamine; Electron Transport; Ferrous Compounds; Humans; Hydroxyurea; Nerve Tissue Proteins; Neuroblastoma; Rotenone; Synucleins; Transfection; Uncoupling Agents | 2003 |
Toxic interaction between hydroxyurea and 1-beta-D-arabino-furanosylcytosine on the DNA of a human hepatoma cell line (HEPG2).
Topics: Carcinoma, Hepatocellular; Cell Line, Tumor; Comet Assay; Cytarabine; DNA Damage; DNA Repair; Drug Synergism; Humans; Hydroxyurea; Liver Neoplasms; Mutagens | 2003 |
Antiproliferative efficacy of the third-generation bisphosphonate, zoledronic acid, combined with other anticancer drugs in leukemic cell lines.
Topics: Antineoplastic Agents; Benzamides; Cell Death; Cell Division; Cell Line, Tumor; Cytarabine; Daunorubicin; Diphosphonates; Drug Screening Assays, Antitumor; Drug Synergism; Humans; Hydroxyurea; Imatinib Mesylate; Imidazoles; Leukemia; Leukemia, Myelogenous, Chronic, BCR-ABL Positive; Methotrexate; Piperazines; Pyrimidines; Vincristine; Zoledronic Acid | 2004 |
Repair of cytokine-induced DNA damage in cultured rat islets of Langerhans.
Topics: Animals; Cells, Cultured; Cytarabine; Cytokines; DNA; DNA Damage; DNA Repair; DNA-Formamidopyrimidine Glycosylase; Hydroxyurea; Islets of Langerhans; Nitric Oxide Synthase; Nitroso Compounds; Oxidation-Reduction; Rats; Rats, Wistar | 2004 |
Chk1 is essential for tumor cell viability following activation of the replication checkpoint.
Topics: Antineoplastic Agents; Apoptosis; Cell Cycle; Cell Line, Tumor; Cell Survival; Checkpoint Kinase 1; Checkpoint Kinase 2; Cytarabine; DNA Damage; DNA Replication; DNA, Neoplasm; Histones; Humans; Hydroxyurea; Protein Kinases; Protein Serine-Threonine Kinases; Replication Protein A; RNA, Small Interfering; Tumor Suppressor Protein p53 | 2005 |
Effect of cytosine arabinoside and hydroxyurea on micronucleus formation induced by model clastogens in Chinese hamster V79 cells.
Topics: Animals; Cricetinae; Cricetulus; Cytarabine; Hydroxyurea; Micronuclei, Chromosome-Defective; Micronucleus Tests; Mutagens | 2004 |
Adenomatous polyposis coli influences micronuclei induction by PhIP and acrylamide in mouse erythrocytes.
Topics: Acrylamide; Adenomatous Polyposis Coli; Adenomatous Polyposis Coli Protein; Animals; Colchicine; Cytarabine; DNA Adducts; Epoxy Compounds; Erythrocytes; Female; Flow Cytometry; Hydroxyurea; Imidazoles; Injections, Subcutaneous; Male; Mice; Mice, Inbred C57BL; Mice, Mutant Strains; Micronuclei, Chromosome-Defective; Micronucleus Tests; Mutagens | 2005 |
TRAIL decoy receptors mediate resistance of acute myeloid leukemia cells to TRAIL.
Topics: Acute Disease; Adolescent; Adult; Antineoplastic Agents; Apoptosis; Caspase 3; Caspase 8; Cell Differentiation; Cell Membrane; Cytarabine; Drug Resistance, Neoplasm; Etoposide; Female; GPI-Linked Proteins; Granulocytes; HL-60 Cells; Humans; Hydroxyurea; Leukemia, Myeloid; Leukemia, Promyelocytic, Acute; Male; Middle Aged; Monocytes; Oncogene Proteins, Fusion; Receptors, TNF-Related Apoptosis-Inducing Ligand; Receptors, Tumor Necrosis Factor; Receptors, Tumor Necrosis Factor, Member 10c; Recombinant Fusion Proteins; Tretinoin; Tumor Cells, Cultured; Tumor Necrosis Factor Decoy Receptors; Tumor Stem Cell Assay; U937 Cells | 2005 |
GM-CSF and low-dose cytosine arabinoside in high-risk, elderly patients with AML or MDS.
Topics: Adult; Aged; Aged, 80 and over; Antimetabolites, Antineoplastic; Antineoplastic Combined Chemotherapy Protocols; Cytarabine; Female; Granulocyte-Macrophage Colony-Stimulating Factor; Humans; Hydroxyurea; Leukemia, Myeloid, Acute; Male; Middle Aged; Myelodysplastic Syndromes; Neutropenia; Recombinant Proteins; Retrospective Studies; Risk Assessment; Risk Factors | 2005 |
The t(8;9)(p22;p24) translocation in atypical chronic myeloid leukaemia yields a new PCM1-JAK2 fusion gene.
Topics: Antibiotics, Antineoplastic; Antimetabolites, Antineoplastic; Antineoplastic Agents; Autoantigens; Cell Cycle Proteins; Chromosomes, Human, Pair 8; Chromosomes, Human, Pair 9; Cytarabine; Fatal Outcome; Genetic Variation; Humans; Hydroxyurea; Idarubicin; In Situ Hybridization, Fluorescence; Janus Kinase 2; Karyotyping; Leukemia, Myelogenous, Chronic, BCR-ABL Positive; Male; Middle Aged; Oncogene Proteins, Fusion; Open Reading Frames; Protein Structure, Tertiary; Protein-Tyrosine Kinases; Proto-Oncogene Proteins; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Secondary Prevention; Sequence Analysis, RNA; Translocation, Genetic; Treatment Outcome | 2005 |
Acute myeloid leukemia treatment in patients over 60 years of age. Comparison of symptomatic, palliative, and aggressive therapy.
Topics: Acute Disease; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Cytarabine; Daunorubicin; Female; Hematopoietic Stem Cell Transplantation; Hospitalization; Humans; Hydroxyurea; Leukemia, Myeloid; Male; Middle Aged; Mitoxantrone; Palliative Care; Prognosis; Remission Induction; Retrospective Studies; Survival Analysis; Treatment Outcome | 2005 |
Resistance to 9-beta-D-arabinofuranosyl-2-fluoroadenine due to reduced incorporation into DNA from competition by excess deoxyadenosine triphosphate: implications for different sensitivities to nucleoside analogues.
Topics: Animals; Binding, Competitive; Biotransformation; Cell Line, Tumor; Cell Proliferation; Cytarabine; Deoxyadenine Nucleotides; Deoxycytosine Nucleotides; DNA; Drug Interactions; Drug Resistance, Neoplasm; Hydroxyurea; Mice; Nucleosides; Vidarabine | 2005 |
CML clonal evolution with resistance to single agent imatinib therapy.
Topics: Antineoplastic Combined Chemotherapy Protocols; Benzamides; Cell Transformation, Neoplastic; Clone Cells; Cytarabine; Drug Resistance, Neoplasm; Humans; Hydroxyurea; Imatinib Mesylate; Interferon-alpha; Leukemia, Myelogenous, Chronic, BCR-ABL Positive; Male; Middle Aged; Philadelphia Chromosome; Piperazines; Pyrimidines; Remission Induction; Treatment Failure; Trisomy | 2005 |
Clinical significance of development of Philadelphia-chromosome negative clones in patients with chronic myeloid leukemia treated with imatinib mesylate.
Topics: Acute Disease; Aged; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Benzamides; Bone Marrow; Clone Cells; Cytarabine; Disease Progression; Fatal Outcome; Fusion Proteins, bcr-abl; Granulocyte Colony-Stimulating Factor; Humans; Hydroxyurea; Imatinib Mesylate; In Situ Hybridization, Fluorescence; Interferons; Leukemia, Myelogenous, Chronic, BCR-ABL Positive; Leukemia, Myeloid; Leukemia, Myeloid, Chronic-Phase; Male; Middle Aged; Neoplastic Stem Cells; Philadelphia Chromosome; Piperazines; Protein Kinase Inhibitors; Pyrimidines; Selection, Genetic; Vidarabine | 2005 |
Acute myelogenous leukemia in elderly patients not eligible for intensive chemotherapy: the dark side of the moon.
Topics: Aged; Aged, 80 and over; Antineoplastic Agents; Cytarabine; Female; Health Services for the Aged; Humans; Hydroxyurea; Leukemia, Myeloid, Acute; Male; Middle Aged; Palliative Care; Quality of Life; Retrospective Studies; Survival Analysis; Thioguanine | 2006 |
Trisomy 19 as the sole chromosomal abnormality in proliferative chronic myelomonocytic leukemia.
Topics: Aged; Azacitidine; Chromosome Aberrations; Chromosomes, Human, Pair 19; Cytarabine; Cytogenetic Analysis; Daunorubicin; Decitabine; Dose-Response Relationship, Drug; Fatal Outcome; Female; Humans; Hydroxyurea; Leukemia, Myelomonocytic, Chronic; Male; Middle Aged; Myelodysplastic Syndromes; Phenotype; Steroids; Treatment Outcome | 2006 |
Role of the C-terminal actin binding domain in BCR/ABL-mediated survival and drug resistance.
Topics: Actins; Antineoplastic Agents; Apoptosis; Cell Differentiation; Cell Division; Cell Line, Tumor; Cloning, Molecular; Cytarabine; Drug Resistance, Neoplasm; Fluorescent Antibody Technique; Fusion Proteins, bcr-abl; Humans; Hydroxyurea; Interleukin-3; Leukemia, Myelogenous, Chronic, BCR-ABL Positive; Lipids; Models, Biological; Neoplastic Stem Cells; Protein-Tyrosine Kinases; Temperature | 2006 |
Leukemic infiltration of the knee.
Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Cytarabine; Fatal Outcome; Humans; Hydroxyurea; Knee; Leukemia, Myelomonocytic, Chronic; Leukemic Infiltration; Magnetic Resonance Imaging; Male; Prednisolone | 2006 |
[Modulating effect of antileukemia drugs on the cellular susceptibility in chronic myeloid leukemia to cytotoxic lymphocytes].
Topics: Antineoplastic Combined Chemotherapy Protocols; Busulfan; Cytarabine; Humans; Hydroxyurea; K562 Cells; Leukemia, Myelogenous, Chronic, BCR-ABL Positive; Leukocytes, Mononuclear | 2006 |
Multiple granulocytic sarcomas in essential thrombocythemia.
Topics: Antineoplastic Combined Chemotherapy Protocols; Blood Transfusion; Chromosome Deletion; Chromosomes, Human, Pair 7; Cytarabine; Etoposide; Fatal Outcome; Female; Femoral Fractures; Femoral Neoplasms; Humans; Hydroxyurea; Middle Aged; Mitobronitol; Neoplasm Metastasis; Nitrosourea Compounds; Primary Myelofibrosis; Radiography; Sarcoma, Myeloid; Thrombocythemia, Essential | 2006 |
Gene expression analysis identifies a genetic signature potentially associated with response to alpha-IFN in chronic phase CML patients.
Topics: Adult; Aged; Antineoplastic Agents; Biomarkers, Tumor; Cytarabine; Fusion Proteins, bcr-abl; Gene Expression Profiling; Gene Expression Regulation, Leukemic; Gene Expression Regulation, Neoplastic; Humans; Hydroxyurea; Interferon-alpha; Leukemia, Myeloid, Chronic-Phase; Middle Aged; Oligonucleotide Array Sequence Analysis; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; RNA, Neoplasm | 2007 |
Detection of excision repaired DNA damage in the comet assay by using Ara-C and hydroxyurea in three different cell types.
Topics: Blood Cells; Cell Line; Cell Survival; Comet Assay; Cytarabine; DNA Damage; DNA Repair; Ethyl Methanesulfonate; Humans; Hydroxyurea; Methyl Methanesulfonate | 2009 |
A non-apoptotic function of caspase-3 in pharmacologically-induced differentiation of K562 cells.
Topics: Antineoplastic Agents; Apoptosis; bcl-X Protein; Caspase 3; Cell Differentiation; Cell Survival; Cisplatin; Cytarabine; Doxorubicin; GATA1 Transcription Factor; HSP70 Heat-Shock Proteins; Humans; Hydroxyurea; K562 Cells; Membrane Potential, Mitochondrial; Structure-Activity Relationship | 2009 |
A comparative study of outcomes of idarubicin- and etoposide-intensified conditioning regimens for allogeneic peripheral blood stem cell transplantation in patients with high-risk acute leukemia.
Topics: Acute Disease; Antineoplastic Combined Chemotherapy Protocols; Aspergillus; Busulfan; China; Combined Modality Therapy; Cyclophosphamide; Cytarabine; Disease-Free Survival; Etoposide; Female; Graft Survival; Graft vs Host Disease; Hematologic Neoplasms; Hematopoietic Stem Cell Transplantation; Humans; Hydroxyurea; Idarubicin; Immunosuppressive Agents; Leukemia; Leukemia, Myeloid, Acute; Male; Methylprednisolone; Mucositis; Pneumonia; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Premedication; Retrospective Studies; Risk Factors; Semustine; Transplantation Conditioning; Transplantation, Homologous; Treatment Outcome; Whole-Body Irradiation | 2009 |
Prospective cytomegalovirus monitoring during first-line chemotherapy in patients with acute myeloid leukemia.
Topics: Adult; Antibiotics, Antineoplastic; Antibodies, Viral; Antigens, Viral; Antineoplastic Agents; Antiviral Agents; Cytarabine; Cytomegalovirus; Cytomegalovirus Infections; Daunorubicin; Female; Humans; Hydroxyurea; Incidence; Italy; Leukemia, Myeloid, Acute; Male; Middle Aged; Monitoring, Physiologic; Phosphoproteins; Treatment Outcome; Viral Matrix Proteins; Young Adult | 2010 |
Acute intraoperative tumour lysis syndrome.
Topics: Antineoplastic Combined Chemotherapy Protocols; Cytarabine; Female; Humans; Hydroxyurea; Leukemia, Myeloid, Acute; Middle Aged; Postoperative Complications; Risk Factors; Time Factors; Tumor Lysis Syndrome | 2010 |
Replication factor C recruits DNA polymerase delta to sites of nucleotide excision repair but is not required for PCNA recruitment.
Topics: Binding Sites; Cell Line; Cytarabine; DNA Damage; DNA Polymerase III; DNA Repair; DNA Replication; Fluorescence Recovery After Photobleaching; Gene Knockdown Techniques; Green Fluorescent Proteins; Humans; Hydroxyurea; Kinetics; Models, Biological; Nucleic Acid Synthesis Inhibitors; Proliferating Cell Nuclear Antigen; Recombinant Fusion Proteins; Replication Protein C; RNA, Small Interfering; Ultraviolet Rays | 2010 |
Imatinib increases cytotoxicity of melphalan and their combination allows an efficient killing of chronic myeloid leukemia cells.
Topics: Antineoplastic Combined Chemotherapy Protocols; Apoptosis; Benzamides; Cell Cycle; Cytarabine; DNA Damage; Drug Synergism; Gene Expression; Genes, abl; Humans; Hydroxyurea; Imatinib Mesylate; K562 Cells; Leukemia, Myelogenous, Chronic, BCR-ABL Positive; Melphalan; Piperazines; Pyrimidines; Tumor Stem Cell Assay | 2011 |
[Therapeutic impact of alpha interferon in chronic myelogenous leukaemia].
Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; Blast Crisis; Cytarabine; Female; Fusion Proteins, bcr-abl; Humans; Hydroxyurea; Immunologic Factors; Interferon-alpha; Kaplan-Meier Estimate; Leukemia, Myeloid, Chronic-Phase; Male; Middle Aged; Remission Induction; Retrospective Studies; Socioeconomic Factors; Virus Activation; Young Adult | 2010 |
Preclinical development of the novel Chk1 inhibitor SCH900776 in combination with DNA-damaging agents and antimetabolites.
Topics: Antimetabolites; Antineoplastic Agents; Blotting, Western; Camptothecin; Cell Cycle Checkpoints; Cell Line; Cell Line, Tumor; Cell Proliferation; Cell Survival; Checkpoint Kinase 1; Cytarabine; Deoxycytidine; DNA Breaks, Double-Stranded; DNA Damage; Dose-Response Relationship, Drug; Drug Screening Assays, Antitumor; Drug Synergism; Flow Cytometry; Gemcitabine; Humans; Hydroxyurea; Irinotecan; Molecular Structure; Phosphorylation; Protein Kinase Inhibitors; Protein Kinases; Pyrazoles; Pyrimidines; Staurosporine | 2012 |
Induction chemotherapy versus palliative treatment for acute myeloid leukemia in a consecutive cohort of elderly patients.
Topics: Acute Disease; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Blood Component Transfusion; Chromosome Aberrations; Cohort Studies; Comorbidity; Cytarabine; Daunorubicin; Etoposide; Female; Follow-Up Studies; Humans; Hydroxyurea; Immunophenotyping; Kaplan-Meier Estimate; Karyotyping; Leukemia, Myeloid; Male; Palliative Care; Remission Induction; Retrospective Studies; Serbia; Treatment Outcome | 2012 |
Response of the G2-prophase checkpoint to genotoxic drugs in lymphocytes from healthy individuals.
Topics: Adult; Antibiotics, Antineoplastic; Chromosome Aberrations; Cytarabine; DNA Damage; Doxorubicin; Female; G2 Phase Cell Cycle Checkpoints; Humans; Hydroxyurea; Lymphocytes; Male; Prophase; Young Adult | 2012 |
[Cutaneous infiltratiton by chronic myelononocytic leukemia: presentation of three cases].
Topics: Aged; Antineoplastic Agents; Azacitidine; Cytarabine; Fatal Outcome; Humans; Hydroxyurea; Leukemia, Myelomonocytic, Chronic; Leukemic Infiltration; Male; Skin | 2013 |
Primary distal femur T-cell lymphoma after allogeneic haematopoietic stem cell transplantation for chronic myeloid leukaemia: a rare case report and literature review.
Topics: Adult; Angiogenesis Inhibitors; Antimetabolites, Antineoplastic; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Cisplatin; Cytarabine; Dexamethasone; Harringtonines; Hematopoietic Stem Cell Transplantation; Homoharringtonine; Humans; Hydroxyurea; Leukemia, Myelogenous, Chronic, BCR-ABL Positive; Lymphoma, T-Cell; Male; Neoplasm Invasiveness; Transplantation, Homologous | 2014 |
Establishment of a rapid drug screening system based on embryonic stem cells.
Topics: Animals; Apoptosis; Cell Line; Cell Survival; Cytarabine; Dexamethasone; DNA Fragmentation; Drug Evaluation, Preclinical; Embryonic Stem Cells; Fluorouracil; Hydroxyurea; Indomethacin; Mice | 2015 |
Outcome of Lower-Risk Patients With Myelodysplastic Syndromes Without 5q Deletion After Failure of Erythropoiesis-Stimulating Agents.
Topics: Aged; Aged, 80 and over; Anemia; Antilymphocyte Serum; Antineoplastic Agents; Arsenic; Azacitidine; Chromosome Deletion; Chromosomes, Human, Pair 5; Cyclosporine; Cytarabine; Decitabine; Disease Progression; Enzyme Inhibitors; Erythrocyte Transfusion; Female; Hematinics; Humans; Hydroxyurea; Immunologic Factors; Lenalidomide; Leukemia, Myeloid, Acute; Male; Middle Aged; Myelodysplastic Syndromes; Recurrence; Retreatment; Retrospective Studies; Risk Factors; Survival Rate; Thalidomide; Treatment Failure; Tretinoin; Valproic Acid | 2017 |
Assessment of neurotoxicity of pharmacological compounds during early neural development of human embryonic stem cells.
Topics: Animals; Ascorbic Acid; Cell Differentiation; Cell Survival; Cells, Cultured; Cytarabine; Dexamethasone; Fluorouracil; Human Embryonic Stem Cells; Humans; Hydroxyurea; Indomethacin; Nestin; Neurogenesis | 2017 |
Skin nodules in onset of acute myeloid leukemia, a myelomonocytic variant case.
Topics: Antineoplastic Combined Chemotherapy Protocols; Biopsy; Cytarabine; Daunorubicin; Delayed Diagnosis; Etoposide; Fatal Outcome; Fatigue; Female; Fever; Humans; Hydroxyurea; Leukemia, Myelomonocytic, Acute; Leukemic Infiltration; Leukocytosis; Metrorrhagia; Middle Aged; Myoma; Neoplasms, Multiple Primary; Palliative Care; Skin; Uterine Neoplasms | 2017 |
Hydroxyurea prior to intensive chemotherapy in AML with moderate leukocytosis.
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Cytarabine; Daunorubicin; Female; Hematopoietic Stem Cell Transplantation; Humans; Hydroxyurea; Induction Chemotherapy; Leukemia, Myeloid, Acute; Leukocytosis; Lomustine; Male; Middle Aged; Retrospective Studies; Treatment Outcome | 2018 |
Surmounting Cytarabine-resistance in acute myeloblastic leukemia cells and specimens with a synergistic combination of hydroxyurea and azidothymidine.
Topics: Antineoplastic Agents; Cell Line, Tumor; Cell Proliferation; Cytarabine; Deoxycytidine Kinase; DNA Damage; Drug Resistance, Neoplasm; Drug Synergism; Histones; Humans; Hydroxyurea; Leukemia, Myeloid, Acute; Ubiquitination; Zidovudine | 2019 |
Enzymatic rhamnosylation of anticancer drugs by an α-L-rhamnosidase from Alternaria sp. L1 for cancer-targeting and enzyme-activated prodrug therapy.
Topics: Alternaria; Antineoplastic Agents; Cell Line, Tumor; Cell Survival; Cytarabine; Floxuridine; Glycoside Hydrolases; Humans; Hydroxyurea; Molecular Targeted Therapy; Neoplasms; Prodrugs; Rhamnose | 2019 |
Systemic Metabolomic Profiling of Acute Myeloid Leukemia Patients before and During Disease-Stabilizing Treatment Based on All-Trans Retinoic Acid, Valproic Acid, and Low-Dose Chemotherapy.
Topics: Aged; Aged, 80 and over; Amino Acids; Cytarabine; Drug Therapy; Female; Humans; Hydroxyurea; Leukemia, Myeloid, Acute; Lipid Metabolism; Male; Mercaptopurine; Metabolomics; Middle Aged; Treatment Outcome; Tretinoin; Valproic Acid | 2019 |
Real-world data on treatment patterns and outcomes of hypomethylating therapy in patients with newly diagnosed acute myeloid leukaemia aged ≥ 60 years.
Topics: Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Azacitidine; Cytarabine; Decitabine; Disease-Free Survival; Female; Follow-Up Studies; Humans; Hydroxyurea; Leukemia, Myeloid, Acute; Male; Middle Aged; Retrospective Studies; Survival Rate | 2020 |
Incidence of tumor lysis syndrome in patients with acute myeloid leukemia undergoing low-intensity induction with venetoclax.
Topics: Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Bridged Bicyclo Compounds, Heterocyclic; Cytarabine; Decitabine; Female; Fluid Therapy; Humans; Hydroxyurea; Incidence; Leukemia, Myeloid, Acute; Leukemia, Myelomonocytic, Acute; Leukocytosis; Male; Middle Aged; Phosphate-Binding Proteins; Phosphorus; Proto-Oncogene Proteins c-bcl-2; Retrospective Studies; Sulfonamides; Tumor Lysis Syndrome; Urate Oxidase; Uric Acid | 2021 |
Angiokeratoma-like purpuric palmar nodules following chemotherapy.
Topics: Angiokeratoma; Antineoplastic Combined Chemotherapy Protocols; Cytarabine; Daunorubicin; Diagnosis, Differential; Female; Hand Dermatoses; Humans; Hydroxyurea; Leukemia; Methotrexate; Middle Aged; Purpura; Skin Neoplasms | 2021 |
Urgent cytoreduction for newly diagnosed acute myeloid leukemia patients allows acquisition of pretreatment genomic data and enrollment on investigational clinical trials.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Clinical Trials as Topic; Cytarabine; Cytoreduction Surgical Procedures; Genomics; Humans; Hydroxyurea; Leukemia, Myeloid, Acute; Middle Aged; Prospective Studies; Treatment Outcome; Young Adult | 2022 |