cytarabine and glasdegib

cytarabine has been researched along with glasdegib in 24 studies

Research

Studies (24)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's7 (29.17)24.3611
2020's17 (70.83)2.80

Authors

AuthorsStudies
Chan, G; Cortes, JE; DesJardins, P; Fiedler, W; Heidel, FH; Hellmann, A; Heuser, M; Laird, AD; Ma, WW; Montesinos, P; O'Connell, A; Ottmann, O; Pollyea, DA; Robak, T; Shaik, MN; Smith, BD; Zeremski, M1
Hoy, SM1
By, K; Del Valle, PL; Farrell, AT; Goldberg, KB; Leong, R; Liu, C; Norsworthy, KJ; Pazdur, R; Przepiorka, D; Shen, YL; Sheth, CM; Subramaniam, S; Zhuang, L1
DiNardo, C; Guerra, VA; Konopleva, M1
Fathi, AT1
Robak, T; Wolska-Washer, A1
Goldsmith, SR; Lovell, AR; Schroeder, MA1
Emadi, A; Estey, E; Gale, RP; Karp, JE; Othus, M1
Carraway, HE; Chandhok, NS; Griffiths, EA; Prebet, T1
Burnett, A; Stone, R1
Candoni, A; Chan, G; Cortes, JE; Ferdinand, R; Fiedler, W; Heidel, FH; Heuser, M; Leber, B; Ma, WW; Montesinos, P; O'Brien, T; O'Connell, A; Pollyea, DA; Robak, T; Sekeres, MA; Smith, BD1
Bell, TJ; Bhattacharyya, H; Cappelleri, JC; Cortes, JE; Hoang, CJ; Johnson, C; Kwon, Y; Solem, CT1
Chan, G; Cortes, JE; Lin, S; Ruiz-Garcia, A; Shaik, N1
Candoni, A; Clark, RE; Cortes, JE; Heuser, M; Leber, B; Montesinos, P; Vyas, P; Zeidan, AM1
Chacim, S; Mariz, JM; Tavares, M1
Daver, N; DiNardo, CD; Fathi, AT; Pollyea, DA; Vyas, P; Wei, AH1
Galinsky, I; Hoang, CJ; McBride, A; Newman, MJ; Paul, S; Relias, V; Ryan, JC; Saneeymehri, S; Stanislaus, G; Tobin, J1
Feld, J; Navada, SC; Silverman, LR1
Heaney, ML; Sarkaria, SM1
Foster, MC; Green, SD; Richardson, DR; Zeidner, JF1
Burzdikaite, P; Dapkeviciute, A; Daukelaite, G; Davainis, L; Griskevicius, L; Maneikis, K; Pugaciute, B; Ringeleviciute, U; Staras, V; Zucenka, A1
Bell, T; Brown, A; Cappelleri, JC; Chan, G; Daniele, P; Tremblay, G1
Chan, G; Cortes, JE; Fiedler, W; Heuser, M; Hoang, CJ; Leber, B; Ma, WW; Merchant, A; Montesinos, P; O'Brien, T; O'Connell, A; Papayannidis, C; Pérez-Simón, JA; Sekeres, MA; Smith, BD; Zeremski, M1
Chan, G; Cortes, JE; DiRienzo, CG; Dombret, H; Jeyakumar, D; Jou, E; Liu, X; Ma, W; Mayer, J; Merchant, A; Montesinos, P; Novak, J; O'Brien, T; Robak, T; Roh, W; Sekeres, MA; Shaik, N; Taussig, DC; Tomlinson, B; Wang, J1

Reviews

10 review(s) available for cytarabine and glasdegib

ArticleYear
Glasdegib: First Global Approval.
    Drugs, 2019, Volume: 79, Issue:2

    Topics: Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Benzimidazoles; Cytarabine; Drug Approval; Europe; Hedgehog Proteins; Humans; Leukemia, Myeloid, Acute; Myelodysplastic Syndromes; Phenylurea Compounds; Signal Transduction; United States

2019
Venetoclax-based therapies for acute myeloid leukemia.
    Best practice & research. Clinical haematology, 2019, Volume: 32, Issue:2

    Topics: Aminopyridines; Antineoplastic Combined Chemotherapy Protocols; Benzimidazoles; Bridged Bicyclo Compounds, Heterocyclic; Clinical Trials as Topic; Cytarabine; Daunorubicin; Glycine; Humans; Leukemia, Myeloid, Acute; Phenylurea Compounds; Proto-Oncogene Proteins c-bcl-2; Pyridines; Sulfonamides; Triazines

2019
Recent drug approvals for newly diagnosed acute myeloid leukemia: gifts or a Trojan horse?
    Leukemia, 2020, Volume: 34, Issue:3

    Topics: Antineoplastic Agents; Benzimidazoles; Bridged Bicyclo Compounds, Heterocyclic; Cytarabine; Daunorubicin; Drug Approval; Gemtuzumab; Glycine; Humans; Leukemia, Myeloid, Acute; Phenylurea Compounds; Pyridines; Randomized Controlled Trials as Topic; Staurosporine; Sulfonamides; United States; United States Food and Drug Administration

2020
Advances in non-intensive chemotherapy treatment options for adults diagnosed with acute myeloid leukemia.
    Leukemia research, 2020, Volume: 91

    Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Azacitidine; Benzimidazoles; Bridged Bicyclo Compounds, Heterocyclic; Cytarabine; Decitabine; Gemtuzumab; Glycine; Humans; Leukemia, Myeloid, Acute; Male; Molecular Targeted Therapy; Phenylurea Compounds; Precision Medicine; Pyridines; Recurrence; Remission Induction; Staurosporine; Sulfonamides

2020
AML: New Drugs but New Challenges.
    Clinical lymphoma, myeloma & leukemia, 2020, Volume: 20, Issue:6

    Topics: Aniline Compounds; Antineoplastic Combined Chemotherapy Protocols; Benzimidazoles; Cytarabine; Daunorubicin; Gemtuzumab; Humans; Leukemia, Myeloid, Acute; Phenylurea Compounds; Pyrazines

2020
Selection and management of older patients with acute myeloid leukemia treated with glasdegib plus low-dose cytarabine: expert panel review.
    Leukemia & lymphoma, 2020, Volume: 61, Issue:14

    Topics: Antineoplastic Combined Chemotherapy Protocols; Benzimidazoles; Cytarabine; Humans; Leukemia, Myeloid, Acute; Phenylurea Compounds

2020
New directions for emerging therapies in acute myeloid leukemia: the next chapter.
    Blood cancer journal, 2020, 10-30, Volume: 10, Issue:10

    Topics: Allografts; Antineoplastic Combined Chemotherapy Protocols; Benzimidazoles; Bridged Bicyclo Compounds, Heterocyclic; Cytarabine; Hematopoietic Stem Cell Transplantation; Humans; Leukemia, Myeloid, Acute; Phenylurea Compounds; Quinuclidines; Sulfonamides

2020
Forsaken Pharmaceutical: Glasdegib in Acute Myeloid Leukemia and Myeloid Diseases.
    Clinical lymphoma, myeloma & leukemia, 2021, Volume: 21, Issue:4

    Topics: Animals; Antineoplastic Combined Chemotherapy Protocols; Azacitidine; Benzimidazoles; Cell Line, Tumor; Clinical Trials as Topic; Cytarabine; Drug Approval; Drug Evaluation, Preclinical; Humans; Induction Chemotherapy; Leukemia, Myeloid, Acute; Mice; Phenylurea Compounds; Signal Transduction; Smoothened Receptor; United States

2021
Glasdegib in newly diagnosed acute myeloid leukemia.
    Expert review of anticancer therapy, 2021, Volume: 21, Issue:6

    Topics: Antineoplastic Combined Chemotherapy Protocols; Benzimidazoles; Cytarabine; Hedgehog Proteins; Humans; Leukemia, Myeloid, Acute; Phenylurea Compounds

2021
Secondary AML Emerging After Therapy with Hypomethylating Agents: Outcomes, Prognostic Factors, and Treatment Options.
    Current hematologic malignancy reports, 2021, Volume: 16, Issue:1

    Topics: Animals; Antineoplastic Agents; Azacitidine; Benzimidazoles; Bridged Bicyclo Compounds, Heterocyclic; Cytarabine; Daunorubicin; Gemtuzumab; Humans; Induction Chemotherapy; Leukemia, Myeloid, Acute; Molecular Targeted Therapy; Phenylurea Compounds; Prognosis; Sulfonamides

2021

Trials

8 trial(s) available for cytarabine and glasdegib

ArticleYear
Randomized comparison of low dose cytarabine with or without glasdegib in patients with newly diagnosed acute myeloid leukemia or high-risk myelodysplastic syndrome.
    Leukemia, 2019, Volume: 33, Issue:2

    Topics: Aged; Aged, 80 and over; Antimetabolites, Antineoplastic; Benzimidazoles; Cytarabine; Drug Therapy, Combination; Female; Follow-Up Studies; Humans; Leukemia, Myeloid, Acute; Male; Middle Aged; Myelodysplastic Syndromes; Phenylurea Compounds; Prognosis; Survival Rate

2019
FDA Approval Summary: Glasdegib for Newly Diagnosed Acute Myeloid Leukemia.
    Clinical cancer research : an official journal of the American Association for Cancer Research, 2019, 10-15, Volume: 25, Issue:20

    Topics: Age Factors; Aged; Aged, 80 and over; Antineoplastic Agents; Benzimidazoles; Comorbidity; Cytarabine; Dose-Response Relationship, Drug; Drug Approval; Drug Labeling; Female; Humans; Induction Chemotherapy; Leukemia, Myeloid, Acute; Male; Middle Aged; Phenylurea Compounds; Smoothened Receptor; Survival Analysis; Treatment Outcome; United States; United States Food and Drug Administration

2019
Glasdegib in the treatment of acute myeloid leukemia.
    Future oncology (London, England), 2019, Volume: 15, Issue:28

    Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Benzimidazoles; Cytarabine; Drug Evaluation; Female; Follow-Up Studies; Humans; Leukemia, Myeloid, Acute; Male; Phenylurea Compounds; Prognosis; Survival Rate

2019
A quality-adjusted survival time without symptoms or toxicities analysis of glasdegib plus low-dose cytarabine versus low-dose cytarabine as initial therapy for acute myeloid leukemia in patients who are not considered candidates for intensive chemotherap
    Cancer, 2020, 10-01, Volume: 126, Issue:19

    Topics: Antineoplastic Combined Chemotherapy Protocols; Benzimidazoles; Cytarabine; Female; Humans; Leukemia, Myeloid, Acute; Male; Phenylurea Compounds; Survival Analysis

2020
An evaluation of overall survival in patients with newly diagnosed acute myeloid leukemia and the relationship with glasdegib treatment and exposure.
    Cancer chemotherapy and pharmacology, 2020, Volume: 86, Issue:4

    Topics: Administration, Oral; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Area Under Curve; Benzimidazoles; Cytarabine; Dose-Response Relationship, Drug; Drug Administration Schedule; Hedgehog Proteins; Humans; Kaplan-Meier Estimate; Leukemia, Myeloid, Acute; Male; Middle Aged; Phenylurea Compounds; Time Factors; Treatment Outcome; United States

2020
Glasdegib plus low-dose cytarabine for acute myeloid leukemia: Practical considerations from advanced practitioners and pharmacists.
    Journal of oncology pharmacy practice : official publication of the International Society of Oncology Pharmacy Practitioners, 2021, Volume: 27, Issue:3

    Topics: Aged; Aged, 80 and over; Antimetabolites, Antineoplastic; Antineoplastic Combined Chemotherapy Protocols; Benzimidazoles; Cytarabine; Drug Interactions; Female; Gastrointestinal Diseases; Hematologic Diseases; Humans; Leukemia, Myeloid, Acute; Male; Pharmacists; Phenylurea Compounds; Physicians

2021
Clinical benefit of glasdegib plus low-dose cytarabine in patients with de novo and secondary acute myeloid leukemia: long-term analysis of a phase II randomized trial.
    Annals of hematology, 2021, Volume: 100, Issue:5

    Topics: Aged; Aged, 80 and over; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Benzimidazoles; Cytarabine; Female; Humans; Leukemia, Myeloid, Acute; Male; Middle Aged; Neoplasms, Second Primary; Phenylurea Compounds; Survival Analysis; Treatment Outcome

2021
Glasdegib plus intensive or non-intensive chemotherapy for untreated acute myeloid leukemia: results from the randomized, phase 3 BRIGHT AML 1019 trial.
    Leukemia, 2023, Volume: 37, Issue:10

    Topics: Anemia; Antineoplastic Combined Chemotherapy Protocols; Azacitidine; Cytarabine; Daunorubicin; Humans; Leukemia, Myeloid, Acute; Nausea

2023

Other Studies

6 other study(ies) available for cytarabine and glasdegib

ArticleYear
Glasdegib with Low-Dose Cytarabine: A New Upfront Option for the Vulnerable AML Patient.
    Clinical cancer research : an official journal of the American Association for Cancer Research, 2019, 10-15, Volume: 25, Issue:20

    Topics: Antineoplastic Combined Chemotherapy Protocols; Benzimidazoles; Cytarabine; Hedgehog Proteins; Humans; Leukemia, Myeloid, Acute; Phenylurea Compounds

2019
Glasdegib for the treatment of adult patients with newly diagnosed acute myeloid leukemia or high-grade myelodysplastic syndrome who are elderly or otherwise unfit for standard induction chemotherapy.
    Drugs of today (Barcelona, Spain : 1998), 2019, Volume: 55, Issue:9

    Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Benzimidazoles; Clinical Trials, Phase II as Topic; Cytarabine; Drug Approval; Humans; Induction Chemotherapy; Leukemia, Myeloid, Acute; Myelodysplastic Syndromes; Phenylurea Compounds; Randomized Controlled Trials as Topic; United States; United States Food and Drug Administration

2019
Survival outcomes and clinical benefit in patients with acute myeloid leukemia treated with glasdegib and low-dose cytarabine according to response to therapy.
    Journal of hematology & oncology, 2020, 07-14, Volume: 13, Issue:1

    Topics: Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Benzimidazoles; Blood Transfusion; Cause of Death; Clinical Trials, Phase II as Topic; Combined Modality Therapy; Cytarabine; Female; Follow-Up Studies; Humans; Kaplan-Meier Estimate; Leukemia, Myeloid, Acute; Male; Middle Aged; Molecular Targeted Therapy; Multicenter Studies as Topic; Phenylurea Compounds; Randomized Controlled Trials as Topic; Remission Induction; Treatment Outcome

2020
Compassionate use of glasdegib in combination with low-dose cytarabine for relapsed, refractory acute myeloid leukemia or high-risk myelodysplastic syndrome.
    Annals of hematology, 2021, Volume: 100, Issue:3

    Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Benzimidazoles; Compassionate Use Trials; Cytarabine; Female; Humans; Leukemia, Myeloid, Acute; Male; Middle Aged; Myelodysplastic Syndromes; Phenylurea Compounds

2021
Glasdegib in combination with low-dose Cytarabine for the outpatient treatment of relapsed or refractory acute myeloid leukemia in unfit patients.
    Annals of hematology, 2021, Volume: 100, Issue:5

    Topics: Aged; Aged, 80 and over; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Benzimidazoles; Cytarabine; Female; Humans; Leukemia, Myeloid, Acute; Male; Middle Aged; Phenylurea Compounds; Retrospective Studies; Treatment Outcome

2021
Comparative effectiveness of glasdegib versus venetoclax combined with low-dose cytarabine in acute myeloid leukemia.
    Journal of comparative effectiveness research, 2021, Volume: 10, Issue:7

    Topics: Antineoplastic Combined Chemotherapy Protocols; Benzimidazoles; Bridged Bicyclo Compounds, Heterocyclic; Cytarabine; Humans; Leukemia, Myeloid, Acute; Phenylurea Compounds; Sulfonamides

2021