cytarabine has been researched along with floxuridine in 160 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 121 (75.63) | 18.7374 |
| 1990's | 12 (7.50) | 18.2507 |
| 2000's | 16 (10.00) | 29.6817 |
| 2010's | 10 (6.25) | 24.3611 |
| 2020's | 1 (0.63) | 2.80 |
| Authors | Studies |
|---|---|
| Chen, MS; Prusoff, WH; Schinazi, RF | 1 |
| Abraham, TW; Kalman, TI; McIntee, EJ; Wagner, CR | 1 |
| McIntee, EJ; Wagner, CR | 1 |
| Benz, RD; Contrera, JF; Kruhlak, NL; Matthews, EJ; Weaver, JL | 1 |
| Cordeiro, MN; Fernández, F; García-Mera, X; Helguera, AM; Rodríguez-Borges, JE | 1 |
| Björck, L; Clausen, AR; Piskur, J; Sandrini, MP; Shannon, O | 1 |
| González-Díaz, H; Orallo, F; Quezada, E; Santana, L; Uriarte, E; Viña, D; Yáñez, M | 1 |
| Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A | 1 |
| Choi, SS; Contrera, JF; Hastings, KL; Kruhlak, NL; Sancilio, LF; Weaver, JL; Willard, JM | 1 |
| Ambroso, JL; Ayrton, AD; Baines, IA; Bloomer, JC; Chen, L; Clarke, SE; Ellens, HM; Harrell, AW; Lovatt, CA; Reese, MJ; Sakatis, MZ; Taylor, MA; Yang, EY | 1 |
| Baraniak, D; Celewicz, L; Czarnecka, A; Kleczewska, N; Lewandowska, M; Ruszkowski, P | 1 |
| Celewicz, L; Chojnacka, K; Hoffmann, M; Kacprzak, K; Kleczewska, N; Lewandowska, M; Ruszkowski, P | 1 |
| Celewicz, L; Gajecka, M; Klich, K; Kubicka, MM; Przybylski, P; Pyta, K; Ruszkowski, P | 1 |
| Celewicz, L; Kleczewska, N; Liberska, J; Ruszkowski, P; Singh, A; Trznadel, R | 1 |
| Horiuchi, M; Ichikawa, Y; Maeda, M | 1 |
| Mathews, CK | 1 |
| Yakobson, E; Zaslavsky, V | 1 |
| Lotem, J; Sachs, L | 1 |
| Johnson, RT; Schor, SL; Waldren, CA | 1 |
| Chi, JC; Holtzer, H; Rubinstein, N; Strahs, K | 1 |
| Lin, H | 1 |
| Fields, BN; Soeiro, R; Sveda, MM | 1 |
| Saha, BK; Tolmach, LJ | 1 |
| Chu, MY; Fischer, GA; Hoovis, ML | 1 |
| Brunk, CF; Yaffe, D | 1 |
| Wood, PM | 1 |
| Bedard, DL; Goldwasser, E | 1 |
| Kano, K; Mano, Y | 1 |
| Schabel, FM | 1 |
| Bunge, R; Estridge, M | 1 |
| Azizkhan, JC; Goode, D; Speeg, KV; Stromberg, K | 1 |
| Carlson, MD; Spooner, BS | 1 |
| Calabresi, P; Cummings, FJ; Hoovis, ML | 1 |
| Reiter, RS; Solursh, M | 1 |
| Moertel, CG | 1 |
| Defendi, V; Hirai, K | 1 |
| Balboni, PG; Barbanti-Brodano, G; Fiume, L; Grossi, MP; Mattioli, A; Minia, A | 1 |
| Coppey, J | 1 |
| Brown, M; Rosenthal, LJ | 1 |
| Wintersberger, E; Wintersberger, U | 1 |
| Ashida, N; Baba, M; Ikeda, T; Machida, H; Sakata, S; Shigeta, S | 1 |
| Aran, JM; Plagemann, PG | 1 |
| Senderoff, RI; Smith, DR; Sokoloski, TD; Weber, PA | 1 |
| Allegra, CJ; Chabner, BA; Chu, E; Grem, JL; Johnson, P; Yeh, GC | 1 |
| Darbre, PD; Härkönen, PL; Laaksonen, EI; Solic, N; Valve, EM | 1 |
| Meneghini, R; Ortega, JM; Schumacher, RI; Ventura, AM | 1 |
| Aiba, K; Allegra, CJ; Baram, J; Chabner, BA; Curt, GA; Yeh, GC | 1 |
| Cortés, F; Mateos, S; Ortiz, T; Piñero, J | 2 |
| Kosaka, M; Matsumoto, K; Nishimune, Y; Nishina, Y; Sakuda, M; Sumi, T; Takeda, M | 1 |
| Oorschot, DE | 1 |
| Lycke, E; Svennerholm, B; Ziegler, R | 1 |
| Carl, PL; Goz, B; Tlsty, TD | 1 |
| Burry, RW; Ho, RH; Kniss, DA | 1 |
| Schwendener, RA | 1 |
| Hartmann, HR; Hengartner, H; Rubas, W; Schott, H; Schwendener, RA; Supersaxo, A | 1 |
| FitzGerald, GB; Ratliff, J; Wick, MM | 1 |
| Wawra, E | 1 |
| Belt, JA; Noel, LD | 1 |
| Saneyoshi, M | 1 |
| Benczur, M; Spasokukotskaja, T; Staub, M; Taljanidisz, J | 1 |
| Kato, S; Miyamoto, H | 1 |
| Greenwald, ES | 1 |
| Schneweis, KE | 1 |
| Buskirk, HH; Crim, JA; Johnson, AG; Merritt, K; Petering, HG | 1 |
| Calabresi, P | 1 |
| De Vrye, CE; Fahmy, MJ; Fahmy, OG | 1 |
| Cassidy, EP; Fischer, DS; Welch, AD | 1 |
| Foley, GE; Lazarus, H | 1 |
| Gilden, RV; Huebner, RJ; Kern, J; Lee, YK | 1 |
| Cohen, LS; Studzinski, GP | 1 |
| Heidelberger, C; Umeda, M | 1 |
| Djordjevic, B; Kim, JH | 1 |
| Gilden, RV; Huebner, RJ; Kern, J | 1 |
| Clarkson, B; Fried, J; Okita, T; Ota, K; Sakai, Y; Strife, A | 1 |
| Maloney, B; Minocha, HC | 1 |
| Oxford, JS; Potter, CW | 1 |
| Cremer, NE; Lennette, EH; Oshiro, LS; Teitz, Y | 1 |
| Jacobs, EM; Johnson, FD | 1 |
| Bell, E | 1 |
| Werkheiser, WC | 1 |
| Bhuyan, BK; Fraser, TJ; Scheidt, LG | 1 |
| Heidelberger, C; Huberman, E | 1 |
| Grindey, GB; Nichol, CA | 1 |
| Cohen, SS; Manduka, MJ; Ortiz, PJ | 1 |
| Aasen, J; Haukenes, G | 1 |
| Adamson, DJ; Bowdon, BJ; Vail, MH; Wheeler, GP | 1 |
| Owens, IS; Topper, YJ; Vonderhaar, BK | 1 |
| Hawtrey, AO; Jones, PA; Taderera, JV | 1 |
| Conkie, D; Paul, J | 1 |
| Momparler, RL | 1 |
| Bhuyan, BK; Fraser, TJ | 1 |
| Topper, YJ; Vonderhaar, BK | 2 |
| Chu, MY; Hoovis, ML | 1 |
| Yoshirkura, H | 1 |
| Bedford, JS; Bender, MA; Griggs, HG | 1 |
| Goorha, R; Granoff, A | 1 |
| Selawry, OS | 1 |
| Connor, JD; Fishaut, JM; Lampert, PW | 1 |
| Goldstein, DA; Hall, MR; Lerner, RA; Meinke, W | 1 |
| Belvedere, G; Bossi, A; Donelli, MG; Frigerio, A; Martini, A; Pantarotto, C | 1 |
| Carter, SK; Comis, RL | 1 |
| Chun, LL; Patterson, PH | 1 |
| Mattoccia, LP; Roberti, S | 1 |
| Temin, HM | 1 |
| Herrmann, EC | 1 |
| Plotkin, SA; Stetler, H | 1 |
| Defendi, V; Girardi, AJ | 1 |
| Kates, JR; Schlessinger, K; Winterton, R | 1 |
| Katz, M; Koprowski, H; Müller, D; ter Meulen, V | 1 |
| Batayias, GE; Martins, RR; Waisbren, BA; Walker, WE | 1 |
| Plotkin, SA | 1 |
| Anderson, CW; Gesteland, RF | 1 |
| Poste, G | 1 |
| Eckhart, W; Oxman, MN; Takemoto, KK | 1 |
| Hartley, JW; Lowy, DR; Rowe, WP; Teich, N | 1 |
| Notkins, AL; Yamazaki, S | 1 |
| Fioretti, A; Furukawa, T; Plotkin, S | 1 |
| Sokol, F; Tan, KB | 1 |
| Gologan, R | 1 |
| Girard, M; Manteuil, S | 1 |
| Cooper, N; Moss, B; Paoletti, E | 1 |
| Hadfield, AF; Sartorelli, AC | 1 |
| Khandjian, EW; Léonard, N; Matter, JM; Weil, R | 1 |
| Colsky, J; Cummings, FJ; Gelman, R; Israel, L; Kuperminc, M; Skeel, RT; Tormey, D | 1 |
| Busi, C; Fiume, L; Mattioli, A | 1 |
| Cadman, E; Grant, S | 1 |
| Ensminger, WD; Keller, JH | 1 |
| Burry, RW | 1 |
| Archard, LC | 1 |
| Ritter, EJ | 1 |
| Yamamoto, N; zur Hausen, H | 1 |
| Endo, H; Inokuchi, K; Masuda, H; Yamamoto, M | 1 |
| Hill, DL; Montgomery, JA | 1 |
| Scott, JM; Weir, DG | 1 |
| Dardick, I; Dubsky, M; Kiss, G; Setterfield, G; Sheinin, R | 1 |
| Lee, SH; Sartorelli, AC | 1 |
| Kikuchi, Y; Yamamoto, KI | 1 |
| Higashikuni, N; Sutou, S | 1 |
| Abe, H; Honma, K; Honma, S; Katsuno, Y; Shinohara, K | 1 |
| Inui, N; Sato, S; Takizawa, H | 1 |
| Allegra, CJ; Chabner, BA; Chu, E; Grem, JL; Johnston, PG; Politi, PM; Takimoto, CH | 1 |
| Huang, L; Kennel, SJ; Mori, A | 1 |
| Bastow, KF; Goz, B | 1 |
| Cattaneo-Pangrazzi, RM; Schott, H; Schwendener, RA | 1 |
| Agarwal, RP; Fernandez, M; Han, T | 1 |
| Bauer, W; Fritzer-Szekeres, M; Grusch, M; Hoechtl, T; Horvath, Z; Jaeger, W; Krupitza, G; Mader, RM; Novotny, L; Rauko, P; Saiko, P; Schott, H; Szekeres, T | 1 |
| Agarwal, RP; Bauer, W; Erlach, N; Fritzer-Szekeres, M; Grusch, M; Hoechtl, T; Horvath, Z; Illmer, C; Jaeger, W; Krupitza, G; Mader, RM; Madlener, S; Saiko, P; Schott, H; Szekeres, T | 1 |
| Bader, Y; Fritzer-Szekeres, M; Grusch, M; Hartmann, J; Krupitza, G; Leisser, C; Mader, RM; Madlener, S; Maier, S; Saiko, P; Sasgary, S; Schott, H; Strasser, S; Szekeres, T | 1 |
| Harashima, H; Ito, M; Kamiya, H; Matsuda, A; Ochiai, H | 1 |
| Bally, MB; Harasym, NL; Harasym, TO; Janoff, AS; Johnstone, SA; Mayer, LD; Ramsay, EC; Shew, CR; Tardi, PG | 1 |
| Bader, Y; Bernhaus, A; Fritzer-Szekeres, M; Gueorguieva, M; Krupitza, G; Leisser, C; Mader, RM; Madlener, S; Maier, S; Richter, S; Saiko, P; Schott, H; Strasser, S; Szekeres, T; Wesierska-Gadek, J | 1 |
| Mego, M; Novotny, L; Rauko, P; Saiko, P; Schott, H; Szekeres, T | 1 |
| Eklund, H; Mikkelsen, NE; Munch-Petersen, B | 1 |
| Li, X; Lin, XF; Wang, JL; Wu, Q; Yin, C | 1 |
| Dolan, ME; Gorsic, LK; Huang, RS; Wen, Y; Wheeler, HE; Ziliak, DM | 1 |
| Lin, X; Tang, G; Wang, J; Wu, Q; Yin, C | 1 |
| Jin, L; Li, Y; Liu, X; Lu, L; Qu, J; Xiao, M; Xu, L; Yin, Z | 1 |
| Chang, I; Chang, WJ; Chen, R; Circelli, J; Harpel, Z; Rivera, J; Wei, R; Wu, S | 1 |
13 review(s) available for cytarabine and floxuridine
| Article | Year |
|---|---|
Rationale for adjuvant chemotherapy.
Topics: Animals; Antineoplastic Agents; Breast Neoplasms; Carmustine; Cyclophosphamide; Cytarabine; Doxorubicin; Drug Therapy, Combination; Female; Floxuridine; Fluorouracil; Humans; Lung Neoplasms; Mammary Neoplasms, Experimental; Mice; Neoplasm Metastasis; Neoplasm Transplantation; Neoplasms, Experimental | 1977 |
Antimetabolites.
Topics: Animals; Antimetabolites; Antineoplastic Agents; Cytarabine; Cytidine; Drug Interactions; Drug Resistance; Floxuridine; Fluorouracil; Folic Acid Antagonists; Humans; Methotrexate; Neoplasms | 1991 |
Antimetabolites.
Topics: Animals; Antimetabolites, Antineoplastic; Azacitidine; Cytarabine; Floxuridine; Fluorouracil; Folic Acid Antagonists; Humans; Mercaptopurine; Methotrexate; Purines; Thioguanine | 1987 |
Cancer chemotherapy. II.
Topics: Animals; Antineoplastic Agents; Asparaginase; Azathioprine; Bleomycin; Cytarabine; Dactinomycin; Daunorubicin; Dimethylamines; Doxorubicin; Floxuridine; Fluorouracil; Humans; Hydroxyurea; Imidazoles; Mercaptopurine; Mitomycins; Mitotane; Neoplasms; Nitrosourea Compounds; Pipobroman; Procarbazine; Streptonigrin; Streptozocin; Thioguanine; Triazenes; Triazines; Vinblastine; Vincristine | 1972 |
Mechanisms of chromosomal aberration production. 3. Chemicals and ionizing radiation.
Topics: Alkylating Agents; Animals; Caffeine; Chromosome Aberrations; Cyanides; Cytarabine; Deoxyadenosines; DNA; DNA Repair; DNA Replication; DNA, Single-Stranded; Floxuridine; Hydroxyurea; Mitosis; Models, Biological; Mutagens; Radiation Genetics; Recombination, Genetic; Streptonigrin; Theobromine; Theophylline | 1974 |
Monochemotherapy of bronchogenic carcinoma withs special reference to cell type.
Topics: Adenocarcinoma; Alkylating Agents; Antineoplastic Agents; Carcinoma, Bronchogenic; Cytarabine; Dactinomycin; Daunorubicin; Doxorubicin; Floxuridine; Humans; Hydroxyurea; Lung Neoplasms; Mechlorethamine; Methotrexate; Mitomycins; Nitrosourea Compounds; Plicamycin; Porfiromycin; Procarbazine; Streptonigrin; Thiotepa; Vinblastine | 1973 |
A review of chemotherapy in gastric cancer.
Topics: Adenocarcinoma; Antineoplastic Agents; Carmustine; Chlorambucil; Chromomycins; Cyclophosphamide; Cytarabine; Drug Evaluation; Drug Therapy, Combination; Floxuridine; Fluorouracil; Humans; Mechlorethamine; Methotrexate; Mitomycins; Nitrosourea Compounds; Olivomycins; Stomach Neoplasms | 1974 |
[Aspects of antiviral therapy in herpes infections].
Topics: Animals; Antiviral Agents; Azauridine; Cytarabine; Encephalitis; Floxuridine; Herpes Simplex; Herpesviridae Infections; Humans; Idoxuridine; Immunoglobulins; Immunotherapy; Interferon Inducers; Keratitis, Dendritic | 1972 |
The pharmacology of prodrugs of 5-fluorouracil and 1-beta-D-arabinofuranosylcytosine.
Topics: Acylation; Ancitabine; Animals; Antineoplastic Agents; Chemistry, Pharmaceutical; Cytarabine; Floxuridine; Fluorouracil; Humans; Phospholipids; Pyrimidines; Steroids; Tegafur | 1984 |
Targeting of antiviral drugs by coupling with protein carriers.
Topics: Albumins; alpha-Fetoproteins; Amanitins; Amino Sugars; Animals; Antiviral Agents; Asialoglycoproteins; Chemical Phenomena; Chemistry; Cytarabine; DNA Replication; Ectromelia virus; Fetuins; Floxuridine; Glycoproteins; Hepatitis B; Hepatitis B virus; Humans; Liver; Macrophages; Serum Albumin; Trifluridine; Vidarabine; Virus Replication | 1983 |
Selective uptake and retention of anticancer agents by sensitive cells.
Topics: Animals; Antineoplastic Agents; Cytarabine; Doxorubicin; Floxuridine; Fluorouracil; Humans; Melphalan; Methotrexate; Neoplasms | 1980 |
Drug-induced megaloblastic change.
Topics: Cyclophosphamide; Cytarabine; DNA; Erythrocytes, Abnormal; Floxuridine; Fluorouracil; Folic Acid Antagonists; Humans; Hydroxyurea; Megaloblasts; Methotrexate; Phenytoin; Pyrimethamine; Ribonucleotides; Thymidine Monophosphate; Thymidylate Synthase; Triamterene; Trimethoprim | 1980 |
Antimetabolites.
Topics: Antimetabolites, Antineoplastic; Cytarabine; Drug Design; Drug Resistance; Floxuridine; Fluorouracil; Humans; Methotrexate; Purines | 1993 |
1 trial(s) available for cytarabine and floxuridine
| Article | Year |
|---|---|
Phase II trials of Baker's antifol, bleomycin, CCNU, streptozotocin, tilorone, and 5-fluorodeoxyuridine plus arabinosyl cytosine in metastatic breast cancer.
Topics: Antineoplastic Agents; Bleomycin; Breast Neoplasms; Cytarabine; Drug Evaluation; Drug Therapy, Combination; Female; Floxuridine; Humans; Lomustine; Probability; Streptozocin; Tilorone; Triazines | 1981 |
146 other study(ies) available for cytarabine and floxuridine
| Article | Year |
|---|---|
Synthesis and biological activities of some uronic acids, uronates, uronamides, and urononitriles of pyrimidine nucleosides.
Topics: Animals; Cell Division; Cells, Cultured; Chick Embryo; Pyrimidine Nucleosides; Sarcoma 180; Simplexvirus; Streptococcus; Structure-Activity Relationship; Substrate Specificity; Thymidine Kinase; Thymidylate Synthase; Uronic Acids; Virus Replication | 1978 |
Synthesis and biological activity of aromatic amino acid phosphoramidates of 5-fluoro-2'-deoxyuridine and 1-beta-arabinofuranosylcytosine: evidence of phosphoramidase activity.
Topics: Animals; Cell Division; Cell Line; Cytarabine; Floxuridine; Humans; Magnetic Resonance Spectroscopy; Mice; Organophosphorus Compounds; Phosphoric Monoester Hydrolases; Thymidylate Synthase; Tumor Cells, Cultured | 1996 |
Amino acid phosphoramidate nucleosides: potential ADEPT/GDEPT substrates.
Topics: Acid Phosphatase; Amides; Cell Division; Enzymes; Humans; Leukemia; Nucleosides; Phosphoric Acids; Protein Tyrosine Phosphatases; Substrate Specificity; Tumor Cells, Cultured | 2001 |
Assessment of the health effects of chemicals in humans: II. Construction of an adverse effects database for QSAR modeling.
Topics: Adverse Drug Reaction Reporting Systems; Artificial Intelligence; Computers; Databases, Factual; Drug Prescriptions; Drug-Related Side Effects and Adverse Reactions; Endpoint Determination; Models, Molecular; Quantitative Structure-Activity Relationship; Software; United States; United States Food and Drug Administration | 2004 |
Probing the anticancer activity of nucleoside analogues: a QSAR model approach using an internally consistent training set.
Topics: Algorithms; Antineoplastic Agents; Databases, Factual; Discriminant Analysis; Models, Molecular; Nucleosides; Quantitative Structure-Activity Relationship | 2007 |
Deoxyribonucleoside kinases activate nucleoside antibiotics in severely pathogenic bacteria.
Topics: Animals; Anti-Bacterial Agents; Deoxycytidine; Female; Gemcitabine; Humans; Mice; Mice, Inbred BALB C; Microbial Sensitivity Tests; Molecular Sequence Data; Nucleosides; Phosphotransferases (Alcohol Group Acceptor); Staphylococcal Infections; Staphylococcus aureus; Streptococcal Infections; Streptococcus pyogenes | 2007 |
Quantitative structure-activity relationship and complex network approach to monoamine oxidase A and B inhibitors.
Topics: Computational Biology; Drug Design; Humans; Isoenzymes; Molecular Structure; Monoamine Oxidase; Monoamine Oxidase Inhibitors; Quantitative Structure-Activity Relationship | 2008 |
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship | 2010 |
Development of a phospholipidosis database and predictive quantitative structure-activity relationship (QSAR) models.
Topics: | 2008 |
Preclinical strategy to reduce clinical hepatotoxicity using in vitro bioactivation data for >200 compounds.
Topics: Chemical and Drug Induced Liver Injury; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Decision Trees; Drug Evaluation, Preclinical; Drug-Related Side Effects and Adverse Reactions; Glutathione; Humans; Liver; Pharmaceutical Preparations; Protein Binding | 2012 |
Synthesis of 3'-azido-2',3'-dideoxy-5-fluorouridine phosphoramidates and evaluation of their anticancer activity.
Topics: Antineoplastic Agents; Cell Proliferation; Dose-Response Relationship, Drug; Floxuridine; HeLa Cells; Humans; KB Cells; MCF-7 Cells; Molecular Structure; Structure-Activity Relationship; Tumor Cells, Cultured | 2013 |
Synthesis and anticancer activity of some 5-fluoro-2'-deoxyuridine phosphoramidates.
Topics: Amides; Antineoplastic Agents; Cell Line; Cell Line, Tumor; Cell Proliferation; Cell Survival; Deoxyuridine; Humans; Neoplasms; Phosphoric Acids | 2016 |
Synthesis, Antibacterial, and Anticancer Evaluation of Novel Spiramycin-Like Conjugates Containing C(5) Triazole Arm.
Topics: Anti-Bacterial Agents; Antineoplastic Agents; Cell Line, Tumor; Cycloaddition Reaction; Drug Screening Assays, Antitumor; Gram-Positive Bacteria; Humans; Microbial Sensitivity Tests; Models, Molecular; Solubility; Spiramycin; Structure-Activity Relationship; Thermodynamics; Triazoles | 2016 |
Synthesis and in vitro anticancer activity of new gemcitabine-nucleoside analogue dimers containing methyltriazole or ester-methyltriazole linker.
Topics: Antineoplastic Agents; Cell Line, Tumor; Cell Proliferation; Click Chemistry; Deoxycytidine; Dimerization; Dose-Response Relationship, Drug; Drug Screening Assays, Antitumor; Esters; Gemcitabine; Humans; Molecular Structure; Nucleosides; Structure-Activity Relationship; Triazoles | 2019 |
Induction of differentiated functions which are reversibly suppressed by cytochalasin B.
Topics: Animals; Bromodeoxyuridine; Cell Division; Cell Line; Cell Movement; Culture Media; Cytarabine; Cytochalasin B; Depression, Chemical; Floxuridine; Latex; Leukemia, Myeloid; Mice; Mice, Inbred Strains; Microspheres; Mitosis; Phagocytosis; Polystyrenes; Radiation Effects; Trypsin; X-Rays | 1975 |
Effects of thymidine analogs upon growth control in cultured hormone-dependent ray ovary cells.
Topics: Animals; Bromodeoxyuridine; Cell Differentiation; Cell Division; Cell Line; Cell Survival; Culture Media; Cytarabine; Deoxyuridine; DNA; Female; Floxuridine; Hormones; Hydroxyurea; Idoxuridine; Kinetics; Ovarian Neoplasms; Rats; Thymidine | 1975 |
Control of thymidine kinase synthesis in IHD vaccinia virus-infected thymidine kinase-deficient LM cells.
Topics: Animals; Cell Line; Cell-Free System; Connective Tissue; Cytarabine; Dactinomycin; DNA, Viral; Enzyme Induction; Floxuridine; HeLa Cells; Humans; Mice; Radiation Effects; Thymidine Kinase; Ultraviolet Rays; Vaccinia virus | 1975 |
Control of normal differentiation of myeloid leukemic cells. VI. Inhibition of cell multiplication and the formation of macrophages.
Topics: Animals; Blood; Bromodeoxyuridine; Cell Adhesion; Cell Differentiation; Cell Division; Cell Movement; Clone Cells; Cycloheximide; Cytarabine; Dactinomycin; Endotoxins; Floxuridine; Hydroxyurea; Idoxuridine; Leukemia, Myeloid; Macrophages; Mice; Mitomycins; Thymidine; Vinblastine | 1975 |
Changes in the organization of chromosomes during the cell cycle: response to ultraviolet light.
Topics: Autoradiography; Caffeine; Cell Division; Cell Fusion; Cell Survival; Chromosomes; Cytarabine; DNA, Neoplasm; Floxuridine; HeLa Cells; Humans; Hydroxyurea; Mitosis; Radiation Effects; Thymidine; Tritium; Ultraviolet Rays | 1975 |
Synthesis of myosin heavy and light chains in muscle cultures.
Topics: Adenosine Triphosphatases; Animals; Cell Division; Cells, Cultured; Chick Embryo; Cytarabine; DNA; Egtazic Acid; Fibroblasts; Floxuridine; Molecular Weight; Muscles; Myofibrils; Myosins | 1975 |
Schedule-dependent effect of phase-specific cytotoxic agents on production of hemolytic plaque-forming cells.
Topics: Animals; Antineoplastic Agents; Cytarabine; Dose-Response Relationship, Drug; Floxuridine; Fluorouracil; Male; Methotrexate; Mice; Mice, Inbred AKR; Time Factors | 1976 |
Fate of input oncornavirion RNA--biological studies.
Topics: Adsorption; Cell Line; Cycloheximide; Cytarabine; DNA; DNA, Viral; Ethidium; Floxuridine; Friend murine leukemia virus; Nucleic Acid Hybridization; RNA, Viral; Viral Proteins; Virus Replication | 1976 |
Delayed expression of the x-ray-induced depression of DNA synthesis rate in HeLa S3 cells.
Topics: Cold Temperature; Cytarabine; DNA, Neoplasm; Floxuridine; HeLa Cells; Radiation Effects; Time Factors; X-Rays | 1976 |
Effects of 5-fluorodeoxyuridine on cell viability and uptake of deoxycytidine and (3H)cytosine arabinoside in L5178Y cells.
Topics: Animals; Cells, Cultured; Cytarabine; Deoxycytidine; DNA; Floxuridine; Kinetics; Leukemia; Mice; RNA | 1976 |
The reversible inhibition of myoblast fusion by ethidium bromide (EB).
Topics: Cell Fusion; Cells, Cultured; Chloramphenicol; Cytarabine; DNA; Dose-Response Relationship, Drug; Ethidium; Floxuridine; Hydroxyurea; Methotrexate; Protein Biosynthesis; Rifampin; RNA; Thymidine | 1976 |
Separation of functional Schwann cells and neurons from normal peripheral nerve tissue.
Topics: Animals; Cell Separation; Collagen; Culture Media; Culture Techniques; Cytarabine; Fetus; Floxuridine; Ganglia, Spinal; Neurons, Afferent; Rats; Schwann Cells; Thymidine | 1976 |
On the mechanism of erythropoietin-induced differentiation. XV. Induced transcription restricted by cytosine arabinoside.
Topics: Animals; Bone Marrow; Bone Marrow Cells; Cytarabine; DNA; Erythropoietin; Floxuridine; Hemoglobins; Male; Protein Biosynthesis; Rats; RNA; Transcription, Genetic | 1976 |
Synthesis of the acid-soluble proteins in early cleaving embryos of the sea urchin. Cyclic synthesis of histones.
Topics: Animals; Cytarabine; DNA; Floxuridine; Histones; Lysine; Sea Urchins; Thymidine; Tryptophan | 1976 |
Compositional analysis of growing axons from rat sympathetic neurons.
Topics: Animals; Axons; Biological Transport; Cell Division; Cells, Cultured; Cytarabine; Floxuridine; Ganglia, Autonomic; Membrane Proteins; Peptides; Rats | 1978 |
Stimulation of human chorionic gonadotropin by JAr line choriocarcinoma after inhibition of DNA synthesis.
Topics: Cell Line; Choriocarcinoma; Chorionic Gonadotropin; Cycloheximide; Cytarabine; DNA, Neoplasm; Dose-Response Relationship, Drug; Female; Floxuridine; Humans; Hydroxyurea; Methotrexate; Neoplasm Proteins; Neoplasms, Experimental; Pregnancy; Uterine Neoplasms | 1979 |
Nerve outgrowth by dorsal root ganglia in vitro: stimulation by inhibitors of DNA metabolism in the absence of exogenous nerve growth factor.
Topics: Animals; Arabinose; Cells, Cultured; Chick Embryo; Cytarabine; Cytosine; Dose-Response Relationship, Drug; Floxuridine; Ganglia, Spinal; Hydroxyurea; Nerve Growth Factors; Thymidine | 1979 |
Phase I study of 5-fluorodeoxyuridine plus cytosine arabinoside infusions in patients with solid tumors.
Topics: Adolescent; Adult; Aged; Breast Neoplasms; Cytarabine; Drug Administration Schedule; Drug Evaluation; Drug Therapy, Combination; Female; Floxuridine; Head and Neck Neoplasms; Humans; Infusions, Parenteral; Male; Malignant Carcinoid Syndrome; Middle Aged; Neoplasms | 1979 |
Determination of limb bud chondrocytes during a transient block of the cell cycle.
Topics: Aminopterin; Animals; Bucladesine; Cartilage; Cell Adhesion; Cell Differentiation; Cell Division; Cells, Cultured; Chick Embryo; Colchicine; Cytarabine; DNA; Extremities; Floxuridine; Hydroxyurea; Theophylline; Thymidine | 1975 |
Clinical management of advanced gastrointestinal cancer.
Topics: Adenoma, Islet Cell; Carcinoma, Hepatocellular; Carmustine; Colonic Neoplasms; Cytarabine; Drug Therapy, Combination; Floxuridine; Fluorouracil; Gastrointestinal Neoplasms; Humans; Liver Neoplasms; Lomustine; Malignant Carcinoid Syndrome; Mitomycins; Pancreatic Neoplasms; Rectal Neoplasms; Stomach Neoplasms; Streptozocin | 1975 |
The effects of serum concentration on the level of integration of simian virus (SV40) genome and the transformation frequency in SV40-infected Chinese hamster cells.
Topics: Antigens, Viral; Blood; Bromodeoxyuridine; Cell Line; Cell Transformation, Neoplastic; Colchicine; Culture Media; Cytarabine; DNA; DNA, Viral; Floxuridine; Polyploidy; Simian virus 40 | 1976 |
Activity of albumin conjugates of 5-fluorodeoxyuridine and cytosine arabinoside on poxviruses as a lysosomotropic approach to antiviral chemotherapy.
Topics: Animals; Cell Line; Cytarabine; Ectromelia virus; Ectromelia, Infectious; Floxuridine; Liver; Lysosomes; Macrophages; Mice; Pharmaceutical Vehicles; Poxviridae Infections; Rodent Diseases; Serum Albumin; Vaccinia virus; Virus Replication | 1976 |
Common precursor pathways of Herpes DNA and of repair synthesis in ultraviolet irradiated cells.
Topics: Cells, Cultured; Cytarabine; Deoxyribonucleosides; DNA Repair; DNA, Viral; Floxuridine; Hydroxyurea; Phosphotransferases; Simplexvirus; Ultraviolet Rays; Virus Replication | 1977 |
The control of SV40 transcription during a lytic infection: late RNA synthesis in the presence of inhibitors of DNA replication.
Topics: Cell Line; Chloroquine; Cytarabine; DNA Replication; DNA, Viral; Floxuridine; Kidney; Mutation; Nucleic Acid Hybridization; RNA, Viral; Simian virus 40; Transcription, Genetic | 1977 |
Nuclear localisation of DNA polymerase alpha and DNA synthesis in polyoma virus infected mouse cells.
Topics: Animals; Cell Nucleus; Cells, Cultured; Cytarabine; Cytoplasm; DNA Replication; DNA-Directed DNA Polymerase; DNA, Neoplasm; DNA, Viral; Floxuridine; Hydroxyurea; Polyomavirus; Tumor Virus Infections | 1977 |
In vitro drug combination of 1-beta-D-arabinofuranosyl-E-5-(2-bromovinyl)uracil with anti-human immunodeficiency virus or anticancer nucleosides.
Topics: Antiviral Agents; Arabinofuranosyluracil; Bromouracil; Cytarabine; Drug Combinations; Floxuridine; Fluorouracil; Herpesvirus 3, Human; HIV-1; Humans; Zidovudine | 1992 |
Nucleoside transport-deficient mutants of PK-15 pig kidney cell line.
Topics: Animals; Biological Transport; Carrier Proteins; Cell Division; Cell Line; Clone Cells; Cytarabine; DNA; Escherichia coli; Flow Cytometry; Floxuridine; Hypoxanthine; Hypoxanthines; Kidney; Kinetics; Membrane Proteins; Methotrexate; Mutation; Nucleoside Transport Proteins; Nucleosides; Plasmids; Recombinant Proteins; Swine; Thymidine; Transfection; Tubercidin; Uridine | 1992 |
Evaluation of antiproliferative agents using a cell-culture model.
Topics: Animals; Bleomycin; Cell Count; Cell Division; Cells, Cultured; Colorimetry; Cricetinae; Cytarabine; Drug Evaluation, Preclinical; Floxuridine; Fluorouracil; Tetrazolium Salts; Thiazoles; Time Factors; Uridine | 1990 |
Temperature-sensitive mutants for steroid-sensitive growth of S115 mouse mammary tumor cells.
Topics: Androgens; Animals; Blood; Cell Division; Chloramphenicol O-Acetyltransferase; Cloning, Molecular; Cytarabine; Ethyl Methanesulfonate; Floxuridine; Gammaretrovirus; Gene Expression; Kinetics; Mammary Neoplasms, Experimental; Mice; Mutation; Receptors, Androgen; RNA, Viral; Temperature; Testosterone; Transfection; Tumor Cells, Cultured | 1990 |
Recovery of DNA synthesis from inhibition by ultraviolet light in mammalian cells.
Topics: Animals; Aphidicolin; Cells, Cultured; Cricetinae; Cricetulus; Cytarabine; Dactinomycin; Diterpenes; DNA; DNA Polymerase II; DNA Repair; Floxuridine; RNA; Ultraviolet Rays | 1987 |
G2 effects of DNA-repair inhibitors on chromatid-type aberrations in root-tip cells treated with maleic hydrazide and mitomycin C.
Topics: Caffeine; Cell Cycle; Chromosome Aberrations; Chromosomes; Cytarabine; DNA Damage; DNA Repair; Floxuridine; Hydroxyurea; In Vitro Techniques; Interphase; Maleic Hydrazide; Mitomycin; Mitomycins; Plants; Pyridazines; Thymidine | 1989 |
Inhibition of DNA synthesis causes stem cell differentiation: induction of teratocarcinoma F9 cell differentiation with nucleoside analogues of DNA-synthesis inhibitors and their inducing abilities counterbalanced specifically by normal nucleosides.
Topics: Animals; Bromodeoxyuridine; Cell Differentiation; Cell Line; Cytarabine; DNA Replication; DNA, Neoplasm; Floxuridine; Hematopoietic Stem Cells; Idoxuridine; Kinetics; Mice; Mutation; Nucleosides; Plasminogen Activators; Teratoma; Thymidine Kinase | 1989 |
Effect of fluorodeoxyuridine on neurons and non-neuronal cells in cerebral explants.
Topics: Animals; Astrocytes; Brain; Cell Count; Cell Differentiation; Cytarabine; Dendrites; Embryo, Mammalian; Floxuridine; Organ Culture Techniques; Rats | 1989 |
Herpes simplex virus infection of the rat sensory neuron. Effects of interferon on cultured cells.
Topics: Animals; Cells, Cultured; Cytarabine; Floxuridine; Interferon Type I; Neurons; Rats; Simplexvirus; Uridine; Virus Replication | 1989 |
1-beta-D-arabinofuranosylcytosine enhancement of resistance to several antineoplastic drugs in mammalian tissue culture cells.
Topics: Animals; Antimetabolites, Antineoplastic; Aspartate Carbamoyltransferase; Aspartic Acid; Carbamoyl-Phosphate Synthase (Glutamine-Hydrolyzing); Cell Line; Cricetinae; Cytarabine; Dihydroorotase; Dose-Response Relationship, Drug; Drug Resistance; Floxuridine; Gene Amplification; Methotrexate; Multienzyme Complexes; Phosphonoacetic Acid; Time Factors; Vincristine | 1989 |
Enhanced survival of apparent presynaptic elements on polylysine-coated beads by inhibition of non-neuronal cell proliferation.
Topics: Animals; Animals, Newborn; Bromodeoxyuridine; Cells, Cultured; Central Nervous System; Cerebellum; Cytarabine; Floxuridine; Neuroglia; Rats; Regeneration; Wound Healing | 1985 |
The preparation of large volumes of homogeneous, sterile liposomes containing various lipophilic cytostatic drugs by the use of a capillary dialyzer.
Topics: Cytarabine; Dialysis; Drug Stability; Floxuridine; Humans; Liposomes; Micelles; Renal Dialysis; Sterilization | 1986 |
Effects of caffeine and inhibitors of DNA synthesis on chromatid-type aberrations induced by acetaldehyde in root-tip cells.
Topics: Acetaldehyde; Caffeine; Cells, Cultured; Chromatids; Chromosome Aberrations; Cytarabine; DNA Replication; Floxuridine; Hydroxyurea; Mutagenicity Tests; Plants | 1987 |
[Liposomes as carriers of lipophilic cytosine arabinoside and fluorodeoxyuridine derivatives. Their cytostatic effect and possibilities of tumor cell specific therapy].
Topics: Animals; Antibodies, Monoclonal; Cytarabine; Drug Therapy; Floxuridine; Humans; Leukemia L1210; Liposomes; Mice; Neoplasms, Experimental; Organ Specificity; Prodrugs | 1987 |
Inhibition of thymidylate synthase in intact L1210 cells by ara-C, daunomycin, hydroxyurea and 3,4-dihydroxybenzylamine.
Topics: Animals; Cytarabine; Daunorubicin; Deoxyuridine; DNA; Dopamine; Floxuridine; Hydroxyurea; Kinetics; Leukemia L1210; Methotrexate; Thymidylate Synthase | 1987 |
Microinjected deoxynucleotides for the study of chemical inhibition of DNA synthesis.
Topics: Animals; Aphidicolin; Autoradiography; Cell Nucleus; Cells, Cultured; Cytarabine; Deoxyribonucleotides; Diterpenes; DNA Replication; Floxuridine; Hydroxyurea; Kinetics; Methotrexate; Trifluridine; Tritium | 1988 |
Isolation and characterization of a mutant of L1210 murine leukemia deficient in nitrobenzylthioinosine-insensitive nucleoside transport.
Topics: Animals; Biological Transport; Carrier Proteins; Cytarabine; Floxuridine; Inosine; Leukemia L1210; Membrane Proteins; Mice; Mutation; Nucleoside Transport Proteins; Nucleosides; Thioinosine; Thymidine; Tubercidin; Tumor Cells, Cultured; Uridine | 1988 |
[Recent advances and trends in cancer chemotherapy using nucleoside analogs].
Topics: Animals; Cell Transformation, Neoplastic; Cytarabine; Floxuridine; Humans; Neoplasms; Nucleosides; Structure-Activity Relationship | 1988 |
5-fluorodeoxyuridine decreases the effect of arabinofuranosyl-cytosine in undifferentiated human B lymphocytes.
Topics: B-Lymphocytes; Centrifugation, Density Gradient; Child, Preschool; Cytarabine; Deoxycytidine; DNA; Floxuridine; Humans; T-Lymphocytes; Thymidine; Tritium | 1988 |
Cell surface antigens induced by poxviruses. I. Effects of antimetabolites on cell surface antigens.
Topics: Amnion; Animals; Antigens; Antimetabolites; Cell Line; Chikungunya virus; Cross Reactions; Cytarabine; Dactinomycin; Ectromelia virus; Encephalitis Virus, Japanese; Floxuridine; Fluorescent Antibody Technique; Haplorhini; Hemadsorption Inhibition Tests; Hemagglutination, Viral; Immune Sera; Inclusion Bodies, Viral; Kidney; Myxoma virus; Oncogenic Viruses; Polyomavirus; Poxviridae; Puromycin; Rabbits; Simian virus 40; Vaccinia virus | 1971 |
[Immunologic analysis of the two Herpes simplex type viruses].
Topics: Animals; Antibodies, Viral; Antibody Specificity; Antigens, Viral; Bromodeoxyuridine; Cross Reactions; Cytarabine; Floxuridine; Fluorides; Herpes Simplex; Immunodiffusion; Phenylalanine; Protein Biosynthesis; Rabbits; Simplexvirus; Viral Proteins | 1972 |
Effect of uracil mustard and several antitumor drugs on the primary antibody response in rats and mice.
Topics: Animals; Antibody Formation; Antigen-Antibody Reactions; Carcinoma 256, Walker; Cyclophosphamide; Cytarabine; Endotoxins; Floxuridine; gamma-Globulins; Injections; Mercaptopurine; Mice; Rats; Thiosemicarbazones; Uracil Mustard | 1965 |
Clinical studies with systemic administration of antimetabolites of pyrimidine nucleosides in viral infections.
Topics: Adrenal Gland Neoplasms; Adult; Aged; Antimetabolites; Cytarabine; Female; Floxuridine; Gangrene; Herpes Zoster; Hodgkin Disease; Humans; Idoxuridine; Infant; Lymphoma, Non-Hodgkin; Middle Aged; Neoplasms; Rhabdomyosarcoma; Smallpox; Vaccination; Vaccinia; Virus Diseases | 1965 |
The mutagenic properties of the nucleosides of pyrimidine analogues in Drosophila melanogaster.
Topics: Animals; Antimetabolites; Bromodeoxyuridine; Chromosome Aberrations; Chromosome Disorders; Cytarabine; Deoxyuridine; Drosophila; Floxuridine; Mutagens; Mutation; Nucleosides | 1966 |
Immunosuppression by pyrimidine nucleoside analogs.
Topics: Animals; Antibody Formation; Antimetabolites; Azathioprine; Bromodeoxyuridine; Chloramphenicol; Cytarabine; Cytosine Nucleotides; Erythrocytes; Floxuridine; Hemagglutination Tests; Idoxuridine; Injections, Intraperitoneal; Injections, Subcutaneous; Mercaptoethanol; Mercaptopurine; Methotrexate; Mice; Nucleosides; Sheep | 1966 |
The response in vitro, of continuous cultures of human lymphoblasts (CCRF-CEM cells) to chemotherapeutic agents.
Topics: Animals; Azaserine; Chloramphenicol; Culture Media; Culture Techniques; Cyclophosphamide; Cytarabine; Dactinomycin; Deoxyuridine; Floxuridine; Fluorouracil; Humans; Hydrocortisone; Lymphocytes; Mechlorethamine; Mercaptopurine; Methotrexate; Mitomycins; Puromycin; Thymidine; Triazines; Vincristine | 1967 |
Biological separation of adenovirus T and V antigen synthesis in KB cells.
Topics: Adenoviridae; Antigens; Culture Techniques; Cytarabine; Floxuridine; Humans; Radiation Effects; Temperature; Ultraviolet Rays; Virus Cultivation | 1968 |
Correlation between cell enlargement and nucleic acid and protein content of HeLa cells in unbalanced growth produced by inhibitors of DNA synthesis.
Topics: Cell Division; Culture Techniques; Cytarabine; DNA, Neoplasm; Female; Floxuridine; Growth; HeLa Cells; Humans; Hydroxyurea; Mechlorethamine; Mitomycins; Neoplasm Proteins; Nitrogen Mustard Compounds; RNA, Neoplasm; Thymidine | 1967 |
Fluorinated pyrimidines. XXXI. Mechanisms of inhibition of vaccinia virus replication in HeLa cells by pyrimidine nucleosides.
Topics: Culture Media; Cytarabine; Deoxyuridine; Floxuridine; HeLa Cells; Idoxuridine; Methods; Pyrimidines; Time Factors; Vaccinia virus; Virus Replication | 1969 |
Modification of radiation response in synchronized HeLa cells by metabolic inhibitors: effects of inhibitors of DNA and protein synthesis.
Topics: Cyclohexanes; Cytarabine; DNA; Floxuridine; HeLa Cells; Hydroxyurea; In Vitro Techniques; Mitosis; Protein Biosynthesis; Puromycin; Pyridones; Radiation Effects; Thymidine | 1969 |
T antigens of bovine and canine adenoviruses demonstrated by immunofluorescence.
Topics: Adenoviridae; Animals; Antigens; Cattle; Cell Transformation, Neoplastic; Complement Fixation Tests; Culture Techniques; Cytarabine; Dogs; Embryo, Mammalian; Floxuridine; Fluorescent Antibody Technique; Kidney; Neoplasms, Experimental | 1969 |
Studies of cellular proliferation in human leukemia. 3. Behavior of leukemic cells in three adults with acute leukemia given continuous infusions of 3H-thymidine for 8 or 10 days.
Topics: Acute Disease; Adult; Aged; Autoradiography; Bone Marrow; Bone Marrow Cells; Cell Division; Cell Nucleus; Culture Techniques; Cytarabine; Down Syndrome; Female; Floxuridine; Humans; Karyotyping; Leukemia; Leukocytes; Lymphocytes; Male; Mitosis; Prednisone; Thioguanine; Thymidine; Tritium; Vincristine | 1970 |
Inhibition of fibroma viral deoxyribonucleic acid synthesis by fluorodeoxyuridine and cytosine arabinoside.
Topics: Autoradiography; Culture Techniques; Cytarabine; DNA; DNA Replication; DNA, Viral; Fibroma; Floxuridine; Inclusion Bodies, Viral; Kidney; Nucleosides; Oncogenic Viruses; Thymidine; Tritium; Virus Replication | 1970 |
Immunofluorescence studies of T and virus capsid antigens induced by chick embryo lethal orphan virus.
Topics: Adenoviridae; Animals; Antigens; Chickens; Complement Fixation Tests; Cricetinae; Culture Techniques; Cytarabine; Embryo, Mammalian; Embryo, Nonmammalian; Floxuridine; Fluorescent Antibody Technique; Humans; Immune Sera; Kidney; Rabbits; Rats; Species Specificity; Time Factors | 1970 |
Release of C-type particles from normal rat thymus cultures and those infected with Moloney leukemia virus.
Topics: Animals; Biological Assay; Cell Line; Centrifugation, Density Gradient; Culture Techniques; Cytarabine; Dactinomycin; DNA, Viral; Floxuridine; Fluorescent Antibody Technique; Immune Sera; Mice; Microscopy, Electron; Moloney murine leukemia virus; Rats; RNA, Viral; Spectrum Analysis; Thymus Gland; Tritium; Ultraviolet Rays; Uridine; Viral Proteins | 1971 |
Chemotherapy of metastatic malignant melanoma. Experience with 73 patients.
Topics: Adult; Aged; Antineoplastic Agents; Chlorambucil; Colchicine; Cyclophosphamide; Cytarabine; Eye Neoplasms; Female; Floxuridine; Humans; Hydroxyurea; Idoxuridine; Male; Melanoma; Melphalan; Middle Aged; Neoplasm Metastasis; Nitrogen Mustard Compounds; Nitrosourea Compounds; Skin Neoplasms; Vinblastine; Vincristine; Vulvar Neoplasms | 1971 |
Informational DNA synthesis distinguished from that of nuclear DNA by inhibitors of DNA synthesis.
Topics: Animals; Cell Nucleus; Cells, Cultured; Chick Embryo; Cytarabine; Cytoplasm; Depression, Chemical; DNA; Floxuridine; Genetic Code; Hydroxyurea; Muscles; Thymidine; Tritium | 1971 |
Mathematical simulation in chemotherapy.
Topics: Cell Membrane Permeability; Cytarabine; DNA, Neoplasm; Drug Interactions; Feedback; Floxuridine; Isoquinolines; Kinetics; Methotrexate; Models, Theoretical; Protein Binding; Thiosemicarbazones | 1971 |
Cell cycle phase specificity of antitumor agents.
Topics: Alkaloids; Alkylating Agents; Animals; Antibiotics, Antineoplastic; Antineoplastic Agents; Carbazoles; Cell Line; Chlorambucil; Cricetinae; Cytarabine; Dactinomycin; Depression, Chemical; DNA; Fibroblasts; Floxuridine; In Vitro Techniques; Lung; Melphalan; Mitosis; Neoplasms, Experimental; Nitrosourea Compounds; Nucleosides; Protein Biosynthesis; RNA; Streptozocin; Thiosemicarbazones | 1972 |
The mutagenicity to mammalian cells of pyrimidine nucleoside analogs.
Topics: Animals; Azaguanine; Bromodeoxyuridine; Cell Count; Cell Survival; Cells, Cultured; Clone Cells; Cricetinae; Cytarabine; DNA; Drug Resistance; Floxuridine; Hydroxyurea; Mutagens; Mutation; Pyrimidines | 1972 |
Interaction of drugs inhibiting different steps in the synthesis of DNA.
Topics: Animals; Cells, Cultured; Cytarabine; Depression, Chemical; DNA, Neoplasm; Drug Antagonism; Drug Interactions; Drug Synergism; Feedback; Floxuridine; In Vitro Techniques; Isoquinolines; Leukemia L1210; Methotrexate; Mice; Models, Biological; Thiosemicarbazones | 1972 |
The lethality of some D-arabinosyl nucleotides to mouse fibroblasts.
Topics: Animals; Arabinose; Cell Count; Cell Division; Cell Survival; Cytarabine; Depression, Chemical; Fibroblasts; Floxuridine; In Vitro Techniques; L Cells; Mice; Nucleoside Diphosphate Sugars; Nucleotides | 1972 |
The effect of metabolic inhibitors on the production of vaccinia haemagglutinin.
Topics: Animals; Bromodeoxyuridine; Cattle; Cycloheximide; Cytarabine; Dactinomycin; DNA, Viral; Floxuridine; HeLa Cells; Hemagglutination Inhibition Tests; Hemagglutination Tests; Hemagglutination, Viral; Hemagglutinins, Viral; Humans; Hydroxyurea; Indoles; Mitomycins; Rabbits; Rifampin; Thiosemicarbazones; Vaccinia virus | 1972 |
Comparison of the effects of several inhibitors of the synthesis of nucleic acids upon the viability and progression through the cell cycle of cultured H. Ep. no. 2 cells.
Topics: Antimetabolites; Azaguanine; Carcinoma; Cell Division; Cell Line; Cell Survival; Cytarabine; DNA Replication; Dose-Response Relationship, Drug; Floxuridine; Fluorouracil; Humans; Hydroxyurea; Laryngeal Neoplasms; Mercaptopurine; Methotrexate; Mitosis; Ribonucleosides; Thioguanine; Time Factors; Tritium | 1972 |
Concerning the necessary coupling of development to proliferation of mouse mammary epithelial cells.
Topics: Animals; Caseins; Culture Techniques; Cytarabine; Deoxyribonucleosides; DNA; Enzyme Induction; Epithelial Cells; Epithelium; Female; Floxuridine; Glucosephosphate Dehydrogenase; Hydrocortisone; Insulin; Lactalbumin; Mammary Glands, Animal; Mice; Milk Proteins; Mitosis; Phosphogluconate Dehydrogenase; Pregnancy; Prolactin | 1973 |
Transformation of hamster cells in vitro by 1- -D arabinofuranosylcytosine, 5-fluorodeoxyuridine and hydroxyurea.
Topics: Animals; Cell Transformation, Neoplastic; Cricetinae; Culture Techniques; Cytarabine; Cytosine Nucleotides; DNA; Embryo, Mammalian; Floxuridine; Hydroxyurea; Neoplasm Metastasis; Tritium | 1972 |
Effects of inhibitors of DNA synthesis on the stimulation of mouse erythroid cells by erythropoietin.
Topics: Animals; Bromodeoxyuridine; Cells, Cultured; Cytarabine; DNA; Erythrocytes; Erythropoietin; Fetus; Floxuridine; Hematopoietic Stem Cells; Heme; Hemoglobins; Hydroxyurea; Iron Isotopes; Liver; Mice; Phosphorus Isotopes; RNA; Stimulation, Chemical; Tritium | 1973 |
Inhibition of cytotoxic action of 1- -D-arabinofuranosylcytosine on S-phase HeLa cells by 5-fluorodeoxyuridine.
Topics: Cell Division; Cytarabine; Floxuridine; Half-Life; HeLa Cells; Humans; Phosphates; Tritium | 1973 |
Frozen DON cells as a source for a cell cycle assay of antitumor agents.
Topics: Alkaloids; Animals; Antibiotics, Antineoplastic; Antineoplastic Agents; Biological Assay; Camptothecin; Carbazoles; Cell Division; Cell Line; Cell Survival; Cricetinae; Cryoprotective Agents; Cytarabine; Cytological Techniques; Dactinomycin; Dimethyl Sulfoxide; Floxuridine; Formates; Freezing; Glycerol; Hydroxyurea; Lung; Mitosis; Proteins; Pyridines; Ribonucleosides; Thiosemicarbazones; Time Factors | 1974 |
Critical cell proliferation as a prerequisite for differentiation of mammary epithelial cells.
Topics: Animals; Caseins; Cell Differentiation; Cytarabine; Epithelium; Estradiol; Female; Floxuridine; Glucosephosphate Dehydrogenase; Hydrocortisone; Insulin; Lactalbumin; Lactose Synthase; Mammary Glands, Animal; Mice; Mitosis; Pregnancy; Prolactin; Uridine | 1973 |
Sensitivity of human leukemic cells to anti-cancer agents in culture.
Topics: Animals; Antineoplastic Agents; Azauridine; Cells; Cells, Cultured; Chlorambucil; Culture Media; Cyclophosphamide; Cytarabine; Drug Resistance; Floxuridine; Horses; Humans; Leukemia, Experimental; Mercaptopurine; Methotrexate; Mice; Prednisone; Thioguanine; Vincristine | 1974 |
Effect of arabinosyl-cytosine on the G1-arrested cells which were subsequently induced to divide by medium change.
Topics: Animals; Cell Line; Cells, Cultured; Culture Media; Cytarabine; Deoxycytidine; DNA; Ethidium; Floxuridine; Kidney; Mice; Mice, Inbred Strains; Mitosis; Thymidine; Time Factors; Tritium | 1974 |
Macromolecular synthesis in cells infected by frog virus 3. I. Virus-specific protein synthesis and its regulation.
Topics: Animals; Anura; Carbon Radioisotopes; Cell Line; Cricetinae; Cyprinidae; Cytarabine; Dactinomycin; DNA; DNA Replication; DNA Viruses; Electrophoresis, Polyacrylamide Gel; Epithelial Cells; Floxuridine; In Vitro Techniques; Kidney; Peptides; Protein Biosynthesis; Tritium; Viral Proteins; Virus Replication | 1974 |
Comparative effects of arabinosyl nucleosides upon the postnatal growth and development of the rat.
Topics: Adenine; Animals; Antimetabolites; Antiviral Agents; Arabinose; Behavior, Animal; Cerebellum; Cytarabine; Floxuridine; Growth; Hypoxanthines; Injections, Intraperitoneal; Locomotion; Motor Activity; Nucleosides; Rats; Time Factors | 1974 |
Differential effects of metabolic inhibitors on cytoplasmic membrane associated and nuclear DNA.
Topics: Antimetabolites; Benzyl Compounds; Biological Transport; Bromodeoxyuridine; Carbon Radioisotopes; Cell Division; Cell Line; Cell Membrane; Cell Nucleus; Centrifugation, Density Gradient; Cytarabine; DNA; Ethidium; Floxuridine; Humans; Hydroxyurea; Lymphocytes; Rifampin; Thymidine; Time Factors | 1974 |
Application of gas chromatography-chemical ionization mass fragmentography in the evaluation of bases and nucleoside analogues used in cancer chemotherapy.
Topics: Animals; Antineoplastic Agents; Base Sequence; Chromatography, Gas; Cytarabine; Drug Evaluation; Floxuridine; Fluorouracil; Mass Spectrometry; Mercaptopurine; Methods; Methylation; Mice; Nucleosides; Purines; Pyrimidines; Ribonucleosides | 1974 |
A role of the cell cycle in hormone-dependent differentiation.
Topics: Animals; Carbon Radioisotopes; Cell Division; Cells, Cultured; Cytarabine; DNA; Epithelium; Female; Floxuridine; Galactose; Humans; Hydrocortisone; Insulin; Lactalbumin; Lactation; Lactose Synthase; Mammary Glands, Animal; Placental Lactogen; Pregnancy; Rats; Thymidine; Time Factors; Tritium | 1974 |
The influence of non-neuronal cells on catecholamine and acetylcholine synthesis and accumulation in cultures of dissociated sympathetic neurons.
Topics: Acetylcholine; Animals; Catecholamines; Cells, Cultured; Choline; Cytarabine; Fibroblasts; Floxuridine; Ganglia, Autonomic; Glioma; Neurons; Rats; Sympathetic Nervous System; Uridine | 1974 |
Effect of specific inhibitors on mitochondrial DNA replication in HeLa cells.
Topics: Carbon Radioisotopes; Centrifugation, Density Gradient; Cytarabine; Deoxyadenosines; DNA; DNA Replication; DNA, Mitochondrial; Ethidium; Floxuridine; HeLa Cells; Hydroxyurea; Thymidine; Tritium | 1974 |
Genetic and possible biochemical mechanisms in viral carcinogenesis.
Topics: Avian Sarcoma Viruses; Culture Techniques; Cytarabine; DNA; Floxuridine; Genetics; Methotrexate; Neoplasms, Experimental; Oncogenic Viruses; Radionuclide Imaging; RNA; Tritium | 1966 |
Sensitivity of herpes simplex virus, vaccinia virus, and adenoviruses to deoxyribonucleic acid inhibitors and thiosemicarbazones in a plaque suppression test.
Topics: Adenoviridae; Antiviral Agents; Bromodeoxyuridine; Cytarabine; Cytopathogenic Effect, Viral; Deoxyuridine; Floxuridine; HeLa Cells; Idoxuridine; Simplexvirus; Thiosemicarbazones; Vaccinia virus | 1968 |
Treatment of congenital cytomegalic inclusion disease with antiviral agents.
Topics: Antiviral Agents; Child, Preschool; Cytarabine; Cytomegalovirus Infections; Female; Floxuridine; Humans; Infant; Infant, Newborn; Infant, Newborn, Diseases; Male; Pyrans | 1969 |
Induction of SV40 transplantation antigen (TrAg) during the lytic cycle.
Topics: Animals; Animals, Newborn; Antigens; Bromodeoxyuridine; Cell Line; Cricetinae; Cycloheximide; Cytarabine; Cytopathogenic Effect, Viral; Dactinomycin; Female; Floxuridine; Fluorescent Antibody Technique; Haplorhini; Immune Tolerance; Immunity; Immunization; Kidney; Male; Neoplasms, Experimental; Neutralization Tests; Puromycin; Simian virus 40; Time Factors | 1970 |
Induction of acetylcholinesterase activity in mouse neuroblastoma tissue culture cells.
Topics: Acetylcholinesterase; Animals; Cell Differentiation; Cell Line; Culture Techniques; Cycloheximide; Cytarabine; Dactinomycin; Depression, Chemical; DNA, Neoplasm; Enzyme Induction; Floxuridine; Mice; Neuroblastoma; Synaptic Transmission | 1971 |
Cytochemical evidence for the presence of two viral agents in subacute sclerosing panencephalitis.
Topics: Animals; Brain; Cell Line; Cells, Cultured; Cytarabine; DNA, Viral; Floxuridine; Haplorhini; Histocytochemistry; Kidney; Measles virus; Microscopy, Electron; Papillomaviridae; Polyomaviridae; RNA, Viral; Simian virus 40; Subacute Sclerosing Panencephalitis | 1971 |
A method for determining sensitivities of antiviral drugs in vitro for possible use as clinical consultation.
Topics: Adenoviridae; Animals; Antiviral Agents; Cell Line; Culture Media; Cytarabine; Cytopathogenic Effect, Viral; Floxuridine; Haplorhini; HeLa Cells; Humans; Idoxuridine; Kidney; Lung; Methods; Simplexvirus; Virus Cultivation | 1971 |
Editorial comment: antiviral chemotherapy.
Topics: Cytarabine; Cytomegalovirus Infections; Floxuridine; Herpesviridae Infections; Humans; Idoxuridine; Infant, Newborn; Virus Replication | 1972 |
Pattern of protein synthesis in monkey cells infected by simian virus 40.
Topics: Amino Acid Sequence; Animals; Autoradiography; Cell Line; Cytarabine; DNA Replication; DNA, Viral; Electrophoresis, Disc; Floxuridine; Haplorhini; Kidney; Methionine; Peptides; Phosphorus Isotopes; Simian virus 40; Sulfur Isotopes; Thymidine; Time Factors; Tritium; Trypsin; Uridine; Viral Proteins | 1972 |
Changes in susceptibility of normal cells to agglutination by plant lectins following modification of cell coat material.
Topics: Agglutination; Animals; Carcinoma; Carcinoma, Squamous Cell; Cell Line; Cell Membrane; Cell Transformation, Neoplastic; Chick Embryo; Concanavalin A; Cricetinae; Cycloheximide; Cytarabine; Floxuridine; Humans; Immune Sera; Kidney; Laryngeal Neoplasms; Lectins; Methods; Newcastle disease virus; Simplexvirus; Time Factors; Trypsin; Vitamin A | 1972 |
Polyoma T antigen synthesis by temperature-sensitive mutants of polyoma virus.
Topics: Animals; Antigens, Viral; Cell Line; Cytarabine; DNA Replication; DNA, Viral; Floxuridine; Fluorescent Antibody Technique; Genes; Genetics, Microbial; Mice; Mutation; Polyomavirus; Temperature; Time Factors; Viral Plaque Assay; Virus Replication | 1972 |
Studies of the mechanism of induction of infectious murine leukemia virus from AKR mouse embryo cell lines by 5-iododeoxyuridine and 5-bromodeoxyuridine.
Topics: Animals; Bromodeoxyuridine; Cell Line; Clone Cells; Cytarabine; DNA; Floxuridine; Idoxuridine; Immune Sera; Leukemia Virus, Murine; Light; Mice; Mice, Inbred AKR; Radiation Effects; Thymidine; Time Factors; Ultraviolet Rays; Viral Plaque Assay; Virus Replication | 1973 |
Inhibition of replication of lactic dehydrogenase virus by actinomycin.
Topics: Animals; Culture Techniques; Cytarabine; Dactinomycin; DNA; Drug Resistance, Microbial; Floxuridine; Interferons; L Cells; L-Lactate Dehydrogenase; Mice; Mice, Inbred Strains; Newcastle disease virus; RNA; RNA Viruses; Thymidine; Time Factors; Tritium; Uridine; Vesicular stomatitis Indiana virus; Virus Diseases; Virus Replication | 1973 |
Growth characteristics of cytomegalovirus in human fibroblasts with demonstration of protein synthesis early in viral replication.
Topics: Amino Acids; Antigens, Viral; Bromodeoxyuridine; Carbon Isotopes; Cell Line; Centrifugation, Density Gradient; Complement Fixation Tests; Cytarabine; Cytomegalovirus; Cytopathogenic Effect, Viral; DNA, Viral; Floxuridine; Fluorescent Antibody Technique; Inclusion Bodies, Viral; Lung; Precipitin Tests; Thymidine; Time Factors; Tritium; Viral Proteins; Virus Replication | 1973 |
Enancement of uptake of Simian virus 40 by nuclei of permissive cells.
Topics: Animals; Cell Nucleus; Cells, Cultured; Culture Media; Cycloheximide; Cytarabine; Cytoplasm; Dactinomycin; DNA; Floxuridine; Haplorhini; Histones; Hydroxyurea; Kidney; Kinetics; Magnesium Sulfate; RNA; Simian virus 40; Thymidine; Tritium; Uridine | 1973 |
Inhibitors of DNA synthesis: their influence on replication and transcription of simian virus 40 DNA.
Topics: Animals; Cell Line; Centrifugation, Zonal; Chloroquine; Cytarabine; DNA Replication; Floxuridine; Haplorhini; Hydroxyurea; In Vitro Techniques; Kidney; Lucanthone; Mutation; Nucleic Acid Hybridization; Simian virus 40; Temperature; Thymidine; Time Factors; Transcription, Genetic; Tritium; Virus Replication | 1974 |
Regulation of synthesis of two immunologically distinct nucleic acid-dependent nucleoside triphosphate phosphohydrolases in vaccinia virus-infected HeLa cells.
Topics: Adenosine Triphosphatases; Cycloheximide; Cytarabine; Dactinomycin; DNA; Enzyme Induction; Floxuridine; HeLa Cells; Immune Sera; Neutralization Tests; Nucleotidases; Phosphoric Monoester Hydrolases; Rifampin; Thiosemicarbazones; Vaccinia virus; Virus Replication | 1974 |
Simian virus 40 and polyoma virus stimulate overall cellular RNA and protein synthesis.
Topics: Antigens, Neoplasm; Cell Nucleus; Cells, Cultured; Cytarabine; Cytoplasm; Floxuridine; Kinetics; Polyomavirus; Protein Biosynthesis; RNA; Simian virus 40; Virus Replication | 1980 |
Modulation of 1-beta-D-arabinofuranosylcytosine metabolism and cytotoxicity in L1210 cells by fluoropyrimidine pretreatment.
Topics: Animals; Arabinofuranosylcytosine Triphosphate; Cell Line; Cell Survival; Clone Cells; Cytarabine; Deoxyribonucleotides; Deoxyuridine; Drug Interactions; Floxuridine; Fluorodeoxyuridylate; Fluorouracil; Leukemia L1210; Mice; Uridine | 1982 |
Stability of cancer chemotherapeutic agents in a totally implanted drug delivery system.
Topics: Antineoplastic Agents; Cytarabine; Drug Stability; Floxuridine; Infusions, Parenteral; Methotrexate; Vinblastine | 1982 |
Antimitotic drugs that enhance neuronal survival in olfactory bulb cell cultures.
Topics: Animals; Bromodeoxyuridine; Cells, Cultured; Cytarabine; Depression, Chemical; Floxuridine; Hydroxyurea; Methotrexate; Mitosis; Olfactory Bulb; Potassium; Rats; Rats, Inbred Strains; Thymidine | 1983 |
Synthesis of full-length, virus genomic DNA by nuclei of vaccinia-infected HeLa cells.
Topics: Cell Fractionation; Cell Nucleus; Centrifugation, Density Gradient; Cytarabine; Cytoplasm; DNA, Viral; Floxuridine; Genes, Viral; HeLa Cells; Humans; Nucleic Acid Hybridization; Thymidine; Vaccinia virus | 1983 |
Potentiation of teratogenesis.
Topics: Animals; Antibiotics, Antineoplastic; Cytarabine; DNA; Drug Synergism; Embryo, Mammalian; Female; Floxuridine; Gestational Age; Glycine; Hydroxyurea; Pregnancy; Purines; Rats; Rats, Inbred Strains; Teratogens | 1984 |
Effect of inhibition of DNA synthesis on Epstein--Barr virus induction by tumor promoters.
Topics: Antigens, Viral; Cytarabine; DNA; Floxuridine; Herpesvirus 4, Human; Humans; Idoxuridine; Phorbols; Tetradecanoylphorbol Acetate; Virus Activation | 1980 |
Hydroxyurea inhibits degradation of internalized epidermal growth factor in HeLa cells.
Topics: Antineoplastic Agents; Cycloheximide; Cytarabine; DNA Replication; Epidermal Growth Factor; ErbB Receptors; Floxuridine; HeLa Cells; Humans; Hydroxyurea; Kinetics; Protein Biosynthesis; Receptors, Cell Surface; Transcription, Genetic | 1982 |
Relationship between chromatin structure and replication in mouse L-cells.
Topics: Animals; Chromatin; Cycloheximide; Cytarabine; DNA Replication; Floxuridine; Hydroxyurea; Isoleucine; L Cells; Methotrexate; Mice; Mitomycin; Mitomycins; Protein Biosynthesis; Structure-Activity Relationship | 1980 |
The effects of inhibitors of DNA biosynthesis on the cytotoxicity of 6-thioguanine.
Topics: Animals; Cells, Cultured; Cytarabine; DNA; DNA Replication; Floxuridine; Hydroxyurea; Interphase; Leukemia, Experimental; Mice; Thioguanine | 1981 |
Studies on micronuclei time response and on the effects of multiple treatments of mutagens on induction of micronuclei.
Topics: Animals; Busulfan; Cell Nucleus; Colchicine; Cyclophosphamide; Cytarabine; Ethyl Methanesulfonate; Floxuridine; Male; Methotrexate; Methyl Methanesulfonate; Mice; Mitomycins; Mutagenicity Tests; Mutagens; Time Factors; Triethylenemelamine; Vincristine | 1981 |
An optimal, generalized sampling time of 30 +/- 6 h after double dosing in the mouse peripheral blood micronucleus test.
Topics: 2-Acetylaminofluorene; 9,10-Dimethyl-1,2-benzanthracene; Animals; Antineoplastic Agents; Carcinogens; Colchicine; Cyclophosphamide; Cytarabine; Floxuridine; Fluorouracil; Kinetics; Methotrexate; Mice; Mice, Inbred Strains; Micronucleus Tests; Mitomycin; Mutagens; Reticulocytes; Sulfuric Acid Esters; Time Factors | 1995 |
Two distinct oscillators in the rat suprachiasmatic nucleus in vitro.
Topics: Animals; Arginine Vasopressin; Circadian Rhythm; Cytarabine; Floxuridine; In Vitro Techniques; Mitosis; N-Methylaspartate; Rats; Rats, Wistar; Suprachiasmatic Nucleus; Vasoactive Intestinal Peptide | 1995 |
Mouse strain differences in induction of micronuclei by base analogues and nucleosides.
Topics: Adenine; Animals; Bromodeoxyuridine; Bromouracil; Cytarabine; Erythrocytes; Female; Floxuridine; Guanosine; Mercaptopurine; Mice; Mice, Inbred BALB C; Mice, Inbred C57BL; Mice, Inbred DBA; Micronucleus Tests; Mitogens; Nucleosides; Purines; Pyrimidines; Species Specificity; Thymidine; Uridine | 1993 |
Immunotargeting of liposomes containing lipophilic antitumor prodrugs.
Topics: Animals; Antibodies, Monoclonal; Antineoplastic Agents; Binding Sites; Cholesterol; Cytarabine; Cytidine Diphosphate Diglycerides; Doxorubicin; Drug Carriers; Floxuridine; Gangliosides; Liposomes; Male; Mice; Mice, Inbred BALB C; Phosphatidylcholines; Phosphatidylethanolamines; Polyethylene Glycols; Prodrugs; Surface Properties | 1993 |
A possible role for topoisomerase II in cell death and N-phosphonoacetyl-L-aspartate-resistance frequency and its enhancement by 1-beta-D-arabinofuranosyl cytosine and 5-fluoro-2'-deoxyuridine.
Topics: Animals; Antimetabolites, Antineoplastic; Aspartic Acid; Cell Death; Cell Line; Cricetinae; Cytarabine; DNA; DNA Topoisomerases, Type II; Drug Resistance; Drug Synergism; Enzyme Induction; Etoposide; Floxuridine; Gene Amplification; Humans; Kidney; Phosphonoacetic Acid | 1997 |
The novel heterodinucleoside dimer 5-FdU-NOAC is a potent cytotoxic drug and a p53-independent inducer of apoptosis in the androgen-independent human prostate cancer cell lines PC-3 and DU-145.
Topics: Androgens; Antimetabolites, Antineoplastic; Apoptosis; Biotransformation; Cell Cycle; Cell Division; Cytarabine; Dimerization; Dose-Response Relationship, Drug; Enzyme Inhibitors; Floxuridine; Fluorodeoxyuridylate; Humans; Hydrolysis; Male; Neoplasms, Hormone-Dependent; Phosphodiesterase I; Phosphoric Diester Hydrolases; Prodrugs; Prostatic Neoplasms; Thymidylate Synthase; Tumor Cells, Cultured; Tumor Suppressor Protein p53 | 2000 |
Reduced cellular transport and activation of fluoropyrimidine nucleosides and resistance in human lymphocytic cell lines selected for arabinosylcytosine resistance.
Topics: Antimetabolites, Antineoplastic; Biological Transport; Cell Line; Cytarabine; Drug Resistance, Multiple; Drug Resistance, Neoplasm; Drug Screening Assays, Antitumor; Floxuridine; Fluorouracil; HL-60 Cells; Humans | 2001 |
In vitro and in vivo antitumor activity of novel amphiphilic dimers consisting of 5-fluorodeoxyuridine and arabinofuranosylcytosine.
Topics: Animals; Antineoplastic Agents; Apoptosis; Cell Line, Tumor; Colorectal Neoplasms; Cytarabine; Drug Resistance, Neoplasm; Floxuridine; Humans; Mice; Surface-Active Agents | 2004 |
Cytotoxic effects of novel amphiphilic dimers consisting of 5-fluorodeoxyuridine and arabinofuranosylcytosine in cross-resistant H9 human lymphoma cells.
Topics: Antineoplastic Agents; Cell Line, Tumor; Cell Survival; Cytarabine; Dimerization; Floxuridine; Humans; Lymphoma; Phosphorylation | 2005 |
Analysis of mechanisms contributing to AraC-mediated chemoresistance and re-establishment of drug sensitivity by the novel heterodinucleoside phosphate 5-FdUrd-araC.
Topics: Antimetabolites, Antineoplastic; Apoptosis; Breast Neoplasms; Cell Cycle; Cell Line, Tumor; Cytarabine; Drug Resistance, Neoplasm; Female; Floxuridine; Humans; Molecular Structure | 2006 |
Transient expression of Drosophila melanogaster deoxynucleoside kinase gene enhances cytotoxicity of nucleoside analogs.
Topics: Animals; Cell Death; Cytarabine; Deoxycytosine Nucleotides; Drosophila melanogaster; Floxuridine; Gene Expression; HeLa Cells; Humans; Molecular Structure; Phosphotransferases (Alcohol Group Acceptor) | 2006 |
Ratiometric dosing of anticancer drug combinations: controlling drug ratios after systemic administration regulates therapeutic activity in tumor-bearing mice.
Topics: Animals; Antineoplastic Combined Chemotherapy Protocols; Camptothecin; Cell Line, Tumor; Cisplatin; Cytarabine; Daunorubicin; Dose-Response Relationship, Drug; Drug Synergism; Floxuridine; Humans; Irinotecan; Liposomes; Mice; Neoplasms; Xenograft Model Antitumor Assays | 2006 |
5-FdUrd-araC heterodinucleoside re-establishes sensitivity in 5-FdUrd- and AraC-resistant MCF-7 breast cancer cells overexpressing ErbB2.
Topics: Antimetabolites, Antineoplastic; Apoptosis; Breast Neoplasms; Caspase 7; Cell Cycle; Cell Proliferation; Cyclin D1; Cytarabine; Dimerization; Drug Resistance, Neoplasm; Female; Floxuridine; Humans; Receptor, ErbB-2; Tumor Cells, Cultured | 2006 |
In vitro and in vivo antileukemic effect of novel dimers consisting of 5-fluorodeoxyuridine and arabinofuranosylcytosine.
Topics: Animals; Antineoplastic Agents; Body Weight; Cell Line, Tumor; Cell Proliferation; Cell Survival; Cytarabine; Dimerization; Female; Floxuridine; Inhibitory Concentration 50; Leukemia L1210; Leukemia P388; Male; Mice; Mice, Inbred DBA; Time Factors | 2007 |
Structural studies of nucleoside analog and feedback inhibitor binding to Drosophila melanogaster multisubstrate deoxyribonucleoside kinase.
Topics: Adenosine Diphosphate; Animals; Antimetabolites; Bromodeoxyuridine; Cytarabine; Cytidine Triphosphate; Drosophila melanogaster; Drosophila Proteins; Feedback; Floxuridine; Guanosine Triphosphate; Hydrogen Bonding; Inhibitory Concentration 50; Kinetics; Models, Chemical; Models, Molecular; Phosphotransferases (Alcohol Group Acceptor); Protein Binding; Protein Structure, Secondary; Structure-Activity Relationship; Thymine Nucleotides; X-Ray Diffraction; Zalcitabine; Zidovudine | 2008 |
Multidrug nanoparticles based on novel random copolymer containing cytarabine and fluorodeoxyuridine.
Topics: Antimetabolites, Antineoplastic; Cytarabine; Drug Carriers; Floxuridine; Nanoparticles; Polymers | 2010 |
Chemotherapeutic-induced apoptosis: a phenotype for pharmacogenomics studies.
Topics: Antineoplastic Agents; Apoptosis; Biomarkers, Pharmacological; Carboplatin; Caspases; Cell Line, Tumor; Cisplatin; Cytarabine; Floxuridine; Genome-Wide Association Study; Glutamates; Guanine; Humans; Paclitaxel; Pemetrexed; Pharmacogenetics; Phenotype; Quantitative Trait Loci; Twins, Monozygotic | 2011 |
Glucose-functionalized multidrug-conjugating nanoparticles based on amphiphilic terpolymer with enhanced anti-tumorous cell cytotoxicity.
Topics: Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Hepatocellular; Cytarabine; Drug Carriers; Drug Delivery Systems; Floxuridine; Glucose; Hep G2 Cells; Humans; Liver Neoplasms; Microscopy, Confocal; Nanoparticles; Polymers | 2013 |
Enzymatic rhamnosylation of anticancer drugs by an α-L-rhamnosidase from Alternaria sp. L1 for cancer-targeting and enzyme-activated prodrug therapy.
Topics: Alternaria; Antineoplastic Agents; Cell Line, Tumor; Cell Survival; Cytarabine; Floxuridine; Glycoside Hydrolases; Humans; Hydroxyurea; Molecular Targeted Therapy; Neoplasms; Prodrugs; Rhamnose | 2019 |
Effects of six pyrimidine analogs on the growth of Tetrahymena thermophila and their implications in pyrimidine metabolism.
Topics: Antimetabolites; Cytarabine; Floxuridine; Fluorouracil; Gemcitabine; Nucleosides; Pyrimidines; Tetrahymena thermophila; Thymine; Uracil | 2023 |