cytarabine has been researched along with cytosine in 80 studies
Timeframe | Studies, this research(%) | All Research% |
---|---|---|
pre-1990 | 34 (42.50) | 18.7374 |
1990's | 11 (13.75) | 18.2507 |
2000's | 22 (27.50) | 29.6817 |
2010's | 13 (16.25) | 24.3611 |
2020's | 0 (0.00) | 2.80 |
Authors | Studies |
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Anderson, JE; Giblett, ER; Teng, YS | 1 |
Carlson, MD; Spooner, BS | 1 |
Mak, TW; Wan, CW | 1 |
Balzarini, J; De Clercq, E; Neyts, J; Snoeck, R | 1 |
Holliday, R | 1 |
Jones, PA; Michalowsky, LA | 1 |
Datta, G; Gurnani, S; Hosur, RV; Khetrapal, CL; Verma, NC | 1 |
Banerjee, A; Biswas, G; Bose, A; Iitaka, Y | 1 |
Jehn, U; Knüppel, W; Wilmanns, W | 1 |
Wingfield, HJ | 1 |
Atkinson, K; Clink, HM; Kay, HE; McElwain, TJ; Powles, R; Wells, DG | 1 |
Buck, M; Cleeland, R; Grunberg, E; Prince, HN | 1 |
Ganeshaguru, K; Hoffbrand, AV; Tattersall, MH | 1 |
DeYoung, JL; Lin, AJ; Notari, RE; Witiak, DT | 1 |
Fairley, GH | 1 |
Gish, DT; Neil, GL; Wechter, WJ | 1 |
Baker, RM; Mankovitz, R; Siminovitch, L; Thompson, LH; Till, JE; Whitmore, GF; Wright, JA | 1 |
Cardoni, A; Chin, ML; Notari, RE | 1 |
Grindey, GB; Kline, I; Saslaw, LD; Waravdekar, VS | 1 |
Falco, EA; Fox, JJ; Miller, N; Wempen, I | 1 |
Ikeda, K; Miura, K; Mizuno, Y; Ueda, T | 1 |
Lenaz, L; Philips, FS; Sternberg, SS | 1 |
Bouchard, J; Chabot, GG; Momparler, RL | 1 |
Datta, G; Gurnani, S; Khetrapal, CL; Ramanathan, KV; Suryaprakash, N | 1 |
Flentje, M; Goldschmidt, H; Haas, R; Hunstein, W; Karcher, A; Möhle, R; Moos, M; Wannenmacher, M; Witt, B | 1 |
Parson, SH; Price, JF; Ribchester, RR | 1 |
Cheng, YC; Chu, CK; Gao, Z; Grove, KL; Guo, X; Liu, SH | 1 |
Cheng, YC; Grove, KL | 1 |
Andrei, G; De Clercq, E; Snoeck, R | 1 |
Blick, G; Garton, T; Griegor, P; Hopkins, U; LaGravinese, L; Whiteside, M | 1 |
Hou, J; Major, EO | 1 |
Hanaoka, K; Hisaoka, M; Ikeda, T; Iwabuchi, H; Kaneko, M; Kobayashi, T; Kurakata, S; Matsuda, A; Mitsuhashi, Y; Miura, S; Nakagawa, A; Nomura, T; Sasaki, T; Shibayama, T; Suzuki, M; Tanaka, K; Tanzawa, F; Tomida, A; Tsuruo, T; Wataya, Y | 1 |
Bachratá, M; Bílková, J; Novotný, L; Rauko, P; Stankovicová, M | 1 |
Chocarro Martinez, A; Garcia Garcia, I; Gonzalez Lopez, A | 1 |
Cheng, YC; Chou, KM; Kukhanova, M | 1 |
Lewis, D; Schon, F; Tubridy, N; Wells, C | 1 |
Dumontet, C; Galmarini, CM; Mackey, JR | 1 |
Johnson, SA | 1 |
Cass, CE; Clarke, ML; Gourdeau, H; Jolivet, J; Lafrenière, RG; Lee, N; Mackey, JR; Mowles, D; Ouellet, F; Richard, A; Selner, M; Young, JD | 1 |
Ait Arkoub, Z; Arnulf, B; Chebbi, F; Fillet, AM; Lefrere, F; Varet, B | 1 |
Giles, FJ | 1 |
Cortes, JE; Douer, D; Estey, EH; Faderl, S; Garcia-Manero, G; Giles, FJ; Jeha, SS; Kantarjian, HM; Koller, CA; Levine, AM; O'Brien, SM; Thomas, DA | 1 |
Berry, DA; Cortes, JE; Estey, EH; Faderl, S; Ferrajoli, A; Garcia-Manero, G; Giles, FJ; Kantarjian, HM; O'Brien, S; Thomas, DA; Verstovsek, S; Wathen, JK; Xiao, LC | 1 |
Chen, X; Wiemer, DF | 1 |
Barbeau, S; Bouffard, DY; Gourdeau, H; Hamelin, B; Jolivet, J; Leblond, L; Ouellet, F; Richard, A | 1 |
CHU, MY; FISCHER, GA | 2 |
TALLEY, RW; VAITKEVICIUS, VK | 1 |
KAUFMAN, HE; MALONEY, ED | 1 |
BUTHALA, DA | 1 |
BOSTWICK, L; EVANS, JS; MENGEL, GD | 1 |
EVANS, JS; MENGEL, GD | 1 |
BOSTWICK, L; EVANS, JS; MENGEL, GD; MUSSER, EA | 1 |
KITAHARA, T; MELNICK, JL; RAPP, F | 1 |
KENSLER, CJ; WODINSKY, I | 1 |
ADVOCATE, S; GORDON, DM | 1 |
Boivin, AJ; Gourdeau, H; Momparler, RL | 1 |
Kiechle, FL; Zhang, X | 1 |
Auré, K; Béhin, A; Lafitte, C; Louillet, F; Sanson, M; Vernant, JP | 1 |
Bricaire, F; Caumes, E; Chapelon-Abric, C; Martinez, V; Piette, JC; Sanson, M; Seilhean, D; Terrier, B; Vaghefi, P | 1 |
Murayama, S; Saito, Y | 1 |
Kishida, S | 1 |
Fakhouri, F; Gasnault, J; Hügle, T; Hummel, A; Jablonski, M; Martinez, F; Sanson, M; Terrier, B | 1 |
Benhadji, K; Calvo, F; Chiao, J; Cvitkovic, E; Faivre, S; Galmarini, CM; Ghoul, A; Green, SR; Le Tourneau, C; Raymond, E; Serova, M | 1 |
Liu, X; Matsuda, A; Plunkett, W; Wang, Y | 1 |
Choi, S; Choi, WJ; Jeong, LS; Kang, YJ; Kim, HO; Lee, H; Lee, HW; Lee, JH; Lee, SK; Tosh, DK | 1 |
Bauerschmitz, GJ; Cerullo, V; Diaconu, I; Escutenaire, S; Hemminki, A; Hernandez-Alcoceba, R; Kanerva, A; Pesonen, S | 1 |
Bachelez, H; Gasnault, J; Le Roux-Villet, C; Michel, L; Taoufik, Y | 1 |
Briel, J; Gocke, CD; Hess, AD; Kanakry, CG; Karp, JE; Kos, F; Levitsky, H; Luznik, L; Meyer, C; Smith, BD; Thoburn, C | 1 |
Ikwuagwu, J; Patel, A; Patel, J | 1 |
Czemerska, M; Grzybowska-Izydorczyk, O; Pluta, A; Robak, T; Szmigielska-Kapłon, A; Wierzbowska, A; Wolska, A | 1 |
Andrei, G; Krecmerová, M; Lebeau, I; Snoeck, R; Topalis, D | 1 |
Burnett, AK; Hills, RK | 1 |
Campbell, DO; Czernin, J; Lee, JT; Radu, CG; Satyamurthy, N | 1 |
Botta, B; Calcaterra, A; D'Acquarica, I; Filippi, A; Fraschetti, C; Piccirillo, S; Rondino, F; Speranza, M | 1 |
Liu, XJ; Nowak, B; Plunkett, W; Wang, YQ | 1 |
Burnett, AK; Cahalin, P; Clark, RE; Hemmaway, C; Hills, RK; Khwaja, A; Milligan, D; Panoskaltsis, N; Russell, N | 1 |
Loignon, M; Toma, E | 1 |
Al Abo, M; Huang, SY; Kiselev, E; Liu, X; Plunkett, W; Pommier, Y; Rajapakse, VN; Sasanuma, H; Takeda, S | 1 |
8 review(s) available for cytarabine and cytosine
Article | Year |
---|---|
Combination chemotherapy in malignant diseases.
Topics: Adult; Antineoplastic Agents; Asparaginase; Carmustine; Child; Cyclophosphamide; Cytarabine; Cytosine; Daunorubicin; Drug Therapy, Combination; Hodgkin Disease; Humans; Immunotherapy; Leukemia, Lymphoid; Leukemia, Myeloid, Acute; Lymphoma; Male; Mechlorethamine; Mercaptopurine; Methotrexate; Nitrogen Mustard Compounds; Prednisolone; Prednisone; Procarbazine; Remission, Spontaneous; Vincristine | 1971 |
Nucleoside analogues: mechanisms of drug resistance and reversal strategies.
Topics: 2-Chloroadenosine; 5'-Nucleotidase; Acute Disease; Animals; Antimetabolites, Antineoplastic; Arabinonucleosides; Biological Transport; Carrier Proteins; Cytarabine; Cytidine Deaminase; Cytosine; Deoxyadenosines; Deoxycytidine; Deoxycytidine Kinase; Dioxolanes; DNA Repair; DNA Replication; DNA-Directed DNA Polymerase; Drug Resistance, Neoplasm; Gemcitabine; Hematopoietic Cell Growth Factors; Humans; Leukemia, Myeloid; Lymphoproliferative Disorders; Neoplastic Stem Cells; Nucleosides; Phosphorylation; Phosphotransferases (Alcohol Group Acceptor); Remission Induction; Ribonucleotide Reductases; Vidarabine | 2001 |
Nucleoside analogues in the treatment of haematological malignancies.
Topics: Antimetabolites, Antineoplastic; Arabinonucleosides; Biological Transport; Cladribine; Clinical Trials as Topic; Cytarabine; Cytosine; Deoxycytidine; Dioxolanes; Economics, Pharmaceutical; Gemcitabine; Guidelines as Topic; Hematologic Neoplasms; Humans; Molecular Structure; Nucleosides; Pentostatin; Vidarabine | 2001 |
Troxacitabine-based therapy of refractory leukemia.
Topics: Antineoplastic Combined Chemotherapy Protocols; Clinical Trials, Phase I as Topic; Clinical Trials, Phase II as Topic; Cytarabine; Cytosine; Dioxolanes; Humans; Idarubicin; Leukemia; Remission Induction; Topotecan | 2002 |
[Neuropathology of progressive multifocal leukoencephalopathy].
Topics: AIDS-Related Opportunistic Infections; Antiretroviral Therapy, Highly Active; Antiviral Agents; Brain; Cidofovir; Cytarabine; Cytosine; Demyelinating Diseases; Humans; JC Virus; Leukoencephalopathy, Progressive Multifocal; Oligodendroglia; Organophosphonates | 2007 |
[Progressive multifocal leukoencephalopathy--epidemiology, clinical pictures, diagnosis and therapy].
Topics: AIDS-Related Opportunistic Infections; Anti-HIV Agents; Antiretroviral Therapy, Highly Active; Antiviral Agents; Biomarkers; Cidofovir; Cytarabine; Cytosine; DNA, Viral; Humans; Japan; JC Virus; Leukoencephalopathy, Progressive Multifocal; Organophosphonates; Prognosis; Tomography, X-Ray Computed | 2007 |
Novel and emerging drugs for acute myeloid leukemia: pharmacology and therapeutic activity.
Topics: Adenine Nucleotides; Animals; Arabinonucleosides; Azacitidine; Benzamides; Clofarabine; Cytarabine; Cytosine; Daunorubicin; Decitabine; Dioxolanes; Farnesyltranstransferase; Histone Deacetylase Inhibitors; Humans; Hydrazines; Imatinib Mesylate; Leukemia, Myeloid, Acute; Liposomes; Piperazines; Protein Kinase Inhibitors; Pyrimidines; Sulfonamides; TOR Serine-Threonine Kinases; Valproic Acid; Vascular Endothelial Growth Factor Receptor-1 | 2011 |
Treatment options for progressive multifocal leukoencephalopathy in HIV-infected persons: current status and future directions.
Topics: Anti-HIV Agents; Antiretroviral Therapy, Highly Active; Antiviral Agents; Cidofovir; Coinfection; Cytarabine; Cytosine; HIV Infections; Humans; Immune Reconstitution Inflammatory Syndrome; Leukoencephalopathy, Progressive Multifocal; Mefloquine; Mianserin; Mirtazapine; Organophosphonates; Ritanserin; Serotonin Antagonists | 2016 |
4 trial(s) available for cytarabine and cytosine
Article | Year |
---|---|
Intensive maintenance treatment in acute myelogenous leukemia (AML): single institution experience of a multicenter randomized trial.
Topics: Adolescent; Adult; Aged; Amsacrine; Antineoplastic Combined Chemotherapy Protocols; Clinical Trials as Topic; Cytarabine; Cytosine; Daunorubicin; Dose-Response Relationship, Drug; Drug Administration Schedule; Humans; Leukemia, Myeloid, Acute; Middle Aged; Random Allocation; Vincristine | 1988 |
Randomized phase I/II study of troxacitabine combined with cytarabine, idarubicin, or topotecan in patients with refractory myeloid leukemias.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Child; Child, Preschool; Cytarabine; Cytosine; Dioxolanes; Dose-Response Relationship, Drug; Drug Administration Schedule; Female; Humans; Idarubicin; Leukemia, Myelogenous, Chronic, BCR-ABL Positive; Leukemia, Myeloid; Leukemia, Myeloid, Acute; Male; Middle Aged; Myelodysplastic Syndromes; Topotecan; Treatment Outcome | 2003 |
Adaptive randomized study of idarubicin and cytarabine versus troxacitabine and cytarabine versus troxacitabine and idarubicin in untreated patients 50 years or older with adverse karyotype acute myeloid leukemia.
Topics: Acute Disease; Age Factors; Aged; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Cytarabine; Cytosine; Dioxolanes; Female; Humans; Idarubicin; Infusions, Intravenous; Karyotyping; Leukemia, Myeloid; Male; Middle Aged; Prognosis; Survival; Treatment Outcome | 2003 |
A randomised comparison of the novel nucleoside analogue sapacitabine with low-dose cytarabine in older patients with acute myeloid leukaemia.
Topics: Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Arabinonucleosides; Cytarabine; Cytosine; Female; Follow-Up Studies; Humans; Leukemia, Myeloid, Acute; Male; Middle Aged; Neoplasm Staging; Prognosis; Remission Induction; Survival Rate | 2015 |
68 other study(ies) available for cytarabine and cytosine
Article | Year |
---|---|
Cytidine deaminase: a new genetic polymorphism demonstrated in human granulocytes.
Topics: Azacitidine; Cytarabine; Cytidine; Cytidine Deaminase; Cytosine; Electrophoresis, Starch Gel; Female; Granulocytes; Humans; Leukocytes; Male; Nucleoside Deaminases; Pedigree; Phenotype; Polymorphism, Genetic | 1975 |
Nerve outgrowth by dorsal root ganglia in vitro: stimulation by inhibitors of DNA metabolism in the absence of exogenous nerve growth factor.
Topics: Animals; Arabinose; Cells, Cultured; Chick Embryo; Cytarabine; Cytosine; Dose-Response Relationship, Drug; Floxuridine; Ganglia, Spinal; Hydroxyurea; Nerve Growth Factors; Thymidine | 1979 |
Deoxycytidine kinase and cytosine nucleoside deaminase activities in synchronized cultures of normal rat kidney cells.
Topics: Cell Cycle; Cell Survival; Cells, Cultured; Cytarabine; Cytidine; Cytosine; Deoxycytidine; Nucleoside Deaminases; Phosphotransferases; Substrate Specificity | 1978 |
Particular characteristics of the anti-human cytomegalovirus activity of (S)-1-(3-hydroxy-2-phosphonylmethoxypropyl)cytosine (HPMPC) in vitro.
Topics: Animals; Antiviral Agents; Cidofovir; Cytarabine; Cytidine; Cytomegalovirus; Cytosine; Deoxycytidine; DNA, Viral; Ganciclovir; Humans; Organophosphonates; Organophosphorus Compounds; Tumor Cells, Cultured; Virus Replication | 1991 |
Strong effects of 5-azacytidine on the in vitro lifespan of human diploid fibroblasts.
Topics: 5-Methylcytosine; Azacitidine; Cell Division; Cell Line; Cell Survival; Cytarabine; Cytosine; Decitabine; DNA; Fibroblasts; Humans; Methylation | 1986 |
Differential nuclear protein binding to 5-azacytosine-containing DNA as a potential mechanism for 5-aza-2'-deoxycytidine resistance.
Topics: 5-Methylcytosine; Animals; Azacitidine; Cell Line; Cell Nucleus; Cytarabine; Cytosine; Decitabine; DNA; DNA (Cytosine-5-)-Methyltransferases; DNA-Binding Proteins; Drug Resistance; Methylation; Mice | 1987 |
Mechanism of interaction of the antileukemic drug cytosine arabinoside with aromatic peptides: role of sugar conformation and peptide backbone.
Topics: Amino Acid Sequence; Carbohydrate Conformation; Carbohydrates; Cytarabine; Cytidine; Cytosine; Magnetic Resonance Spectroscopy; Molecular Sequence Data; Peptides; Spectrometry, Fluorescence | 1989 |
Structure of a modified cytosine: an antiviral nucleoside analog, homo-Ara-C.
Topics: Crystallography; Cytarabine; Cytosine; Molecular Conformation | 1988 |
Absence of fungistatic antagonism between flucytosine and cytarabine in vitro and in vivo.
Topics: Candida; Cryptococcus neoformans; Cytarabine; Cytosine; Female; Flucytosine; Humans; Microbial Sensitivity Tests; Middle Aged | 1987 |
Adult acute leukaemia.
Topics: Acute Disease; Administration, Oral; Adult; Aged; Antineoplastic Agents; Cyclophosphamide; Cytarabine; Cytosine; Daunorubicin; Doxorubicin; Drug Therapy, Combination; Humans; Injections, Intravenous; Leukemia; Leukemia, Lymphoid; Leukemia, Myeloid, Acute; Middle Aged; Prednisone; Remission, Spontaneous; Staining and Labeling; Thioguanine; Vincristine | 1974 |
A comparative study of the antitumor and antiviral activity of 1-beta-D-arabinofuranosyl-5-fluorocytosine (FCA) and 1-beta-D-arabinofuranosylcytosine (CA).
Topics: Animals; Antineoplastic Agents; Carcinoma 256, Walker; Carcinoma, Ehrlich Tumor; Culture Techniques; Cytarabine; Cytosine; DNA Viruses; Enterovirus; Herpesviridae Infections; Leukemia L1210; Mammary Neoplasms, Experimental; Methods; Mice; Neoplasms, Experimental; Nucleosides; Orthomyxoviridae; Rabbits; Rats; RNA Viruses; Simplexvirus; Vaccinia virus | 1969 |
The mechanisms of action of three fluorine substituted cytosine analogs: implications for cancer chemotherapy.
Topics: Antineoplastic Agents; Arabinose; Cells, Cultured; Cytarabine; Cytidine; Cytosine; Deoxyuridine; DNA; Flucytosine; Fluorine; Humans; Lymphocytes; Nucleosides; Thymidine; Tritium | 1974 |
Comparative kinetics of cytosine nucleosides. Influence of a 6-methyl substituent on degradation rates and pathways in aqueous buffers.
Topics: Chemical Phenomena; Chemistry; Cytarabine; Cytosine; Deamination; Hydrolysis; Kinetics; Methylation; Nucleosides; Spectrophotometry, Ultraviolet; Structure-Activity Relationship | 1972 |
Nucleic acids. 12. Synthesis of the L enantiomer of 1- -arabinofuranosylcytosine and of O 2 ,O 2' -anhydro-1- -D-arabinofuranosylcytosine.
Topics: Animals; Antineoplastic Agents; Antiviral Agents; Arabinose; Cytarabine; Cytosine; Hemagglutination Tests; Immunosuppressive Agents; Leukemia L1210; Mice; Nucleosides; Stereoisomerism; Structure-Activity Relationship | 1971 |
Selective and nonselective isolation of temperature-sensitive mutants of mouse L-cells and their characterization.
Topics: Animals; Cell Survival; Clone Cells; Cytarabine; Cytosine; L Cells; Leucine; Methods; Mice; Mutation; Nitrosoguanidines; Phenotype; Selection, Genetic; Temperature; Thymidine; Time Factors; Tritium; Uracil | 1971 |
Intermolecular and intramolecular catalysis in deamination of cytosine nucleosides.
Topics: Buffers; Catalysis; Cytarabine; Cytosine; Hydrogen-Ion Concentration; Kinetics; Nucleosides; Spectrophotometry | 1970 |
Sparing action of uridine on the activity of arabinosylcytosine with normal and leukemic mice.
Topics: Animals; Chromatography; Cytarabine; Cytosine; Drug Synergism; Leukemia L1210; Male; Mice; Nucleosides; Spleen; Thymidine; Tritium; Uracil Nucleotides; Uridine | 1968 |
Nucleosides. XLVII. Synthesis of some N4-substituted derivarives of 1-beta-D-arabinofuranosylcytosine and -5-fluorocytosine.
Topics: Animals; Cytarabine; Cytosine; Fluorine; Leukemia L1210; Methods; Mice; Nucleosides; Pyrimidines; Spectrophotometry; Thiouracil; Ultraviolet Rays | 1968 |
Synthetic studies of potential antimetabolites. XI. Syntheses of beta-D-pentofuranosyl-5-methylcytosines.
Topics: Cytarabine; Cytosine; Pyrimidines; Thiamine; Uracil | 1968 |
Cytotoxic effects of 1-beta-D-arabinofuranosyl-5-fluorocytosine and of 1-beta-D-arabinofuranosylcytosine in proliferating tissues in mice.
Topics: Animals; Antimetabolites; Carbon Isotopes; Cell Division; Cytarabine; Cytosine; DNA; Duodenum; Epithelium; Fluorine; Intestine, Small; Male; Mice; Mitosis; Phosphorus; Phosphorus Isotopes; RNA; Spleen; Thymidine; Thymus Gland | 1969 |
Kinetics of deamination of 5-aza-2'-deoxycytidine and cytosine arabinoside by human liver cytidine deaminase and its inhibition by 3-deazauridine, thymidine or uracil arabinoside.
Topics: 3-Deazauridine; Adult; Arabinofuranosyluracil; Azacitidine; Cytarabine; Cytidine Deaminase; Cytosine; Decitabine; Humans; Kinetics; Liver; Nucleoside Deaminases; Substrate Specificity; Thymidine | 1983 |
An NMR study of the interaction of cytosine arabinoside and lysozyme.
Topics: Animals; Chickens; Cytarabine; Cytosine; Egg White; Magnetic Resonance Spectroscopy; Muramidase; Protein Binding | 1982 |
[Sequential high-dose therapy in patients with low-malignity non-Hodgkin's lymphoma].
Topics: Antineoplastic Combined Chemotherapy Protocols; Cyclophosphamide; Cytarabine; Cytosine; Filgrastim; Granulocyte Colony-Stimulating Factor; Humans; Leukapheresis; Lymphoma, Non-Hodgkin; Mitoxantrone; Prospective Studies; Radiotherapy Dosage; Recombinant Proteins; Remission Induction; Stem Cell Transplantation; Whole-Body Irradiation | 1995 |
Cell viability and laminin-induced neurite outgrowth in cultures of embryonic chick neural tube cells: effects of cytosine-B-D-arabinofuranoside.
Topics: Animals; Biological Assay; Cell Survival; Cells, Cultured; Central Nervous System; Chick Embryo; Cytarabine; Cytosine; Deoxycytidine; Laminin; Neurites; Neurons | 1995 |
Anticancer activity of beta-L-dioxolane-cytidine, a novel nucleoside analogue with the unnatural L configuration.
Topics: Animals; Antineoplastic Agents; Carcinoma, Hepatocellular; Cell Division; Colonic Neoplasms; Cytarabine; Cytosine; Dioxolanes; Drug Screening Assays, Antitumor; Humans; KB Cells; Leukemia P388; Liver Neoplasms; Male; Mice; Molecular Structure; Phosphorylation; Prostatic Neoplasms; Stereoisomerism; Tumor Cells, Cultured | 1995 |
Uptake and metabolism of the new anticancer compound beta-L-(-)-dioxolane-cytidine in human prostate carcinoma DU-145 cells.
Topics: Antimetabolites, Antineoplastic; Biological Transport; Cell Line; Cytarabine; Cytosine; Dioxolanes; DNA, Neoplasm; Humans; Kinetics; Male; Prostatic Neoplasms; Tritium; Tumor Cells, Cultured | 1996 |
Patterns of resistance and sensitivity to antiviral compounds of drug-resistant strains of human cytomegalovirus selected in vitro.
Topics: Acyclovir; Adenine; Antiviral Agents; Cells, Cultured; Cidofovir; Cytarabine; Cytomegalovirus; Cytomegalovirus Infections; Cytosine; Drug Resistance, Microbial; Fibroblasts; Foscarnet; Humans; Lung; Organophosphonates; Organophosphorus Compounds; Phosphonoacetic Acid | 1996 |
Successful resolution of progressive multifocal leukoencephalopathy after combination therapy with cidofovir and cytosine arabinoside.
Topics: Adult; Antiviral Agents; Cidofovir; Cytarabine; Cytosine; Drug Therapy, Combination; Humans; Leukoencephalopathy, Progressive Multifocal; Male; Organophosphonates; Organophosphorus Compounds | 1998 |
The efficacy of nucleoside analogs against JC virus multiplication in a persistently infected human fetal brain cell line.
Topics: Anti-HIV Agents; Antiviral Agents; Brain; Cells, Cultured; Cidofovir; Cytarabine; Cytosine; DNA, Viral; Enzyme Inhibitors; Fetus; Humans; JC Virus; Neurons; Nucleosides; Organophosphonates; Organophosphorus Compounds; Papillomavirus Infections; Topotecan; Tumor Virus Infections; Virus Replication; Zidovudine | 1998 |
Antitumor activity and novel DNA-self-strand-breaking mechanism of CNDAC (1-(2-C-cyano-2-deoxy-beta-D-arabino-pentofuranosyl) cytosine) and its N4-palmitoyl derivative (CS-682).
Topics: Administration, Oral; Animals; Antimetabolites, Antineoplastic; Arabinonucleosides; Biotransformation; Breast Neoplasms; Cisplatin; Cytarabine; Cytosine; Deoxycytidine; Deoxycytidine Kinase; DNA Damage; DNA, Neoplasm; Drug Resistance, Neoplasm; Drug Screening Assays, Antitumor; Female; Fluorouracil; Humans; KB Cells; Leukemia P388; Mice; Mice, Inbred BALB C; Mice, Inbred DBA; Mice, Nude; Mitomycin; Molecular Structure; Neoplasm Proteins; Neoplasm Transplantation; Neoplasms, Experimental; Rats; Rats, Nude; Specific Pathogen-Free Organisms; Stomach Neoplasms; Tumor Cells, Cultured; Vincristine | 1999 |
Transformation kinetics of the 5'-chloro-5'-deoxy analogue of arabinosylcytosine.
Topics: Antineoplastic Agents; Cytarabine; Cytidine; Cytosine; Drug Stability; Hydrogen-Ion Concentration; Kinetics; Structure-Activity Relationship; Thermodynamics | 1999 |
Successful resolution of progressive multifocal leukoencephalopathy after combination therapy with cidofovir and cytosine arabinoside.
Topics: AIDS-Related Opportunistic Infections; Antiviral Agents; Cidofovir; Cytarabine; Cytosine; Drug Therapy, Combination; Humans; Leukoencephalopathy, Progressive Multifocal; Organophosphonates; Organophosphorus Compounds; Treatment Outcome | 2000 |
A novel action of human apurinic/apyrimidinic endonuclease: excision of L-configuration deoxyribonucleoside analogs from the 3' termini of DNA.
Topics: Anions; Antineoplastic Agents; Antiviral Agents; Blotting, Western; Carbon-Oxygen Lyases; Cations; Chromatography, Agarose; Chromatography, Ion Exchange; Cytarabine; Cytosine; Deoxycytidine; Deoxycytidine Monophosphate; Deoxyribonuclease IV (Phage T4-Induced); Dioxolanes; DNA; DNA-(Apurinic or Apyrimidinic Site) Lyase; Electrophoresis, Polyacrylamide Gel; Endonucleases; Humans; Oligonucleotides; Recombinant Proteins; Reverse Transcriptase Inhibitors; Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization; Stereoisomerism; Thionucleosides; Tumor Cells, Cultured; Zalcitabine | 2000 |
Unsuccessful treatment with cidofovir and cytarabine in progressive multifocal leukoencephalopathy associated with dermatomyositis.
Topics: Adult; Antiviral Agents; Cidofovir; Cytarabine; Cytosine; Dermatomyositis; Drug Therapy, Combination; Female; Humans; Leukoencephalopathy, Progressive Multifocal; Organophosphonates; Organophosphorus Compounds; Treatment Failure | 2000 |
Progressive multifocal leukoencephalopathy (PML).
Topics: AIDS-Related Opportunistic Infections; Antimetabolites, Antineoplastic; Antiviral Agents; Clinical Trials as Topic; Cytarabine; Cytosine; Drug Therapy, Combination; HIV Infections; Humans; Leukoencephalopathy, Progressive Multifocal | 1998 |
Mechanisms of uptake and resistance to troxacitabine, a novel deoxycytidine nucleoside analogue, in human leukemic and solid tumor cell lines.
Topics: Amino Acid Sequence; Antineoplastic Agents; Biological Transport; Carrier Proteins; Cytarabine; Cytidine Deaminase; Cytosine; Deoxycytidine; Deoxycytidine Kinase; Dioxolanes; Drug Resistance, Neoplasm; Gemcitabine; Humans; Leukemia; Male; Membrane Proteins; Molecular Sequence Data; Nucleoside Transport Proteins; Phosphorylation; Prostatic Neoplasms; Sequence Homology, Amino Acid; Sodium; Stereoisomerism; Tritium; Tumor Cells, Cultured; Uridine | 2001 |
Multiple herpes simplex virus infections with various resistance patterns in a matched unrelated donor transplant recipient.
Topics: Acyclovir; Antineoplastic Agents, Alkylating; Antiviral Agents; Bone Marrow Transplantation; Cidofovir; Combined Modality Therapy; Cyclosporine; Cytarabine; Cytomegalovirus Infections; Cytosine; Drug Resistance, Viral; Fatal Outcome; Foscarnet; Graft vs Host Disease; Herpes Genitalis; Herpes Simplex; Humans; Hydroxyurea; Immunocompromised Host; Immunosuppressive Agents; Interferons; Leukemia, Myelogenous, Chronic, BCR-ABL Positive; Male; Methotrexate; Middle Aged; Organophosphonates; Organophosphorus Compounds; Simplexvirus; Transplantation Conditioning; Whole-Body Irradiation | 2001 |
Alpha-phosphono lactone analogues of cytidine and cytosine arabinoside diphosphates: synthesis via ring closing metathesis.
Topics: Arabinose; Cytarabine; Cytidine; Cytidine Diphosphate; Cytosine; Indicators and Reagents; Lactones; Models, Molecular; Organophosphonates; Stereoisomerism | 2003 |
Complementary antineoplastic activity of the cytosine nucleoside analogues troxacitabine (Troxatyl) and cytarabine in human leukemia cells.
Topics: Animals; Antineoplastic Combined Chemotherapy Protocols; Biological Transport; Cell Line, Tumor; Cell Survival; Cytarabine; Cytosine; Dioxolanes; DNA, Neoplasm; Female; Humans; Inhibitory Concentration 50; Injections, Intraperitoneal; Leukemia, Experimental; Mice; Mice, SCID; Neoplasm Transplantation | 2003 |
A proposed mechanism of action of 1-beta-D-arabinofuranosyl-cytosine as an inhibitor of the growth of leukemic cells.
Topics: Animals; Antineoplastic Agents; Cytarabine; Cytosine; Leukemia, Experimental; Nucleosides; Nucleotides | 1962 |
Megaloblastosis produced by a cytosine antagonist, 1-beta-D-arabinofuranosylcytosine.
Topics: Antimetabolites; Antineoplastic Agents; Bone Marrow; Cytarabine; Cytosine; Humans; Nucleosides | 1963 |
IDU and cytosine arabinoside in experimental herpetic keratitis.
Topics: Cytarabine; Cytosine; Idoxuridine; Keratitis; Keratitis, Dendritic; Keratitis, Herpetic | 1963 |
CELL CULTURE STUDIES ON ANTIVIRAL AGENTS. I. ACTION OF CYTOSINE ARABINOSIDE AND SOME COMPARISONS WITH 5-IODO-2-DEOXYURIDINE.
Topics: Adenoviridae; Animals; Antiviral Agents; Chick Embryo; Cytarabine; Cytosine; Herpesviridae; Idoxuridine; Kidney; Liver; Mice; Newcastle disease virus; Nucleosides; Orthomyxoviridae; Pharmacology; Poultry; Poxviridae; Rabbits; Rats; Research; Simplexvirus; Skin; Tissue Culture Techniques; Vaccinia virus; Virus Cultivation; Viruses | 1964 |
SYNERGISM OF THE ANTINEOPLASTIC ACTIVITY OF CYTOSINE ARABINOSIDE BY PORFIROMYCIN.
Topics: Animals; Anti-Bacterial Agents; Antineoplastic Agents; Body Weight; Cytarabine; Cytosine; Leukemia; Leukemia L1210; Leukemia, Experimental; Mice; Mitomycin; Mitomycins; Neoplasms; Neoplasms, Experimental; Nucleosides; Pharmacology; Porfiromycin; Research; Survival | 1964 |
THE REVERSAL OF CYTOSINE ARABINOSIDE ACTIVITY IN VIVO BY DEOXYCYTIDINE.
Topics: Animals; Antineoplastic Agents; Carcinoma, Ehrlich Tumor; Cytarabine; Cytosine; Deoxycytidine; Leukemia; Leukemia, Experimental; Neoplasms; Neoplasms, Experimental; Nucleosides; Pharmacology; Research; Sarcoma 180 | 1964 |
THE EFFECT OF 1-BETA-D-ARABINOFURANOSYLCYTOSINE HYDROCHLORIDE ON MURINE NEOPLASMS.
Topics: Animals; Anti-Bacterial Agents; Antibodies; Antineoplastic Agents; Blood Cells; Carcinoma, Ehrlich Tumor; Cortisone; Cytarabine; Cytosine; Leukemia L1210; Leukemia, Experimental; Lymphoma; Mercaptopurine; Methotrexate; Mice; Neoplasms; Neoplasms, Experimental; Pharmacology; Research; Sarcoma 180 | 1964 |
TUMOR AND VIRUS ANTIGENS OF SIMIAN VIRUS 40: DIFFERENTIAL INHIBITION OF SYNTHESIS BY CYTOSINE ARABINOSIDE.
Topics: Antigens; Antigens, Viral; Cytarabine; Cytosine; Humans; Idoxuridine; Metabolism; Neoplasms; Nucleosides; Pharmacology; Research; Simian virus 40 | 1965 |
ACTIVITY OF SELECTED COMPOUNDS IN SUBLINE OF LEUKEMIA L1210 RESISTANT TO CYTOSINE ARABINOSIDE (NSC-63878).
Topics: Animals; Antineoplastic Agents; Arabinose; Cytarabine; Cytosine; Leukemia L1210; Mice; Nucleosides; Pharmacology; Research | 1964 |
VACCINIAL BLEPHAROKERATITIS TREATED WITH CYTOSINE ARABINOSIDE.
Topics: Antiviral Agents; Corneal Ulcer; Cytarabine; Cytosine; Drug Therapy; Eyelids; Humans; Idoxuridine; Inflammation; Keratitis; Nucleosides; Smallpox Vaccine; Uveitis | 1965 |
COMPARATIVE STUDIES OF LEUKEMIC CELLS SENSITIVE AND RESISTANT TO CYTOSINE ARABINOSIDE.
Topics: Adenosine Triphosphate; Antineoplastic Agents; Chromatography; Cytarabine; Cytosine; DNA; DNA, Neoplasm; Leukemia; Leukemia, Experimental; Magnesium; Neoplasms; Nucleosides; Pharmacology; Phosphotransferases; Research; RNA; RNA, Neoplasm; Tissue Culture Techniques | 1965 |
Action of troxacitabine on cells transduced with human cytidine deaminase cDNA.
Topics: Antineoplastic Agents; Carcinoma, Non-Small-Cell Lung; Cytarabine; Cytidine Deaminase; Cytosine; Dioxolanes; Drug Resistance, Neoplasm; Humans; Lung Neoplasms; Transduction, Genetic; Tumor Cells, Cultured | 2004 |
Cytosine arabinoside substitution decreases transcription factor-DNA binding element complex formation.
Topics: Binding Sites; CCAAT-Enhancer-Binding Proteins; Cell Line, Tumor; Cytarabine; Cytosine; DNA-Binding Proteins; DNA, Neoplasm; HL-60 Cells; Humans; Macromolecular Substances; Oligonucleotides; Protein Binding; TATA-Box Binding Protein; Transcription Factor AP-2; Transcription Factors | 2004 |
Dramatic improvement in non-AIDS related progressive multifocal leucoencephalopathy.
Topics: Antiviral Agents; Cidofovir; Cytarabine; Cytosine; Drug Therapy, Combination; Hematologic Diseases; Humans; Leukoencephalopathy, Progressive Multifocal; Male; Middle Aged; Organophosphonates; Treatment Outcome | 2005 |
Progressive multifocal leukoencephalopathy mimicking cerebral vasculitis in systemic granulomatosis.
Topics: Adrenal Cortex Hormones; Aged; Anti-Inflammatory Agents; Cerebrospinal Fluid; Cidofovir; Cytarabine; Cytosine; Diagnosis, Differential; DNA, Viral; Fatal Outcome; Hemiplegia; Humans; JC Virus; Leukoencephalopathy, Progressive Multifocal; Male; Organophosphonates; Polymerase Chain Reaction; Tuberculosis; Vasculitis, Central Nervous System | 2007 |
[Progressive multifocal leukoencephalopathy in a non-AIDS patient: high efficiency of combined cytarabine and cidofovir].
Topics: Antiviral Agents; Cidofovir; Cytarabine; Cytosine; Drug Therapy, Combination; Female; Humans; Immunosuppressive Agents; Leukoencephalopathy, Progressive Multifocal; Lupus Erythematosus, Systemic; Middle Aged; Opportunistic Infections; Organophosphonates; Treatment Outcome | 2007 |
Antiproliferative effects of sapacitabine (CYC682), a novel 2'-deoxycytidine-derivative, in human cancer cells.
Topics: 5'-Nucleotidase; Antineoplastic Agents; Apoptosis; Arabinonucleosides; Cell Cycle; Cell Line, Tumor; Cell Proliferation; Cell Survival; Cisplatin; Cytarabine; Cytosine; Deoxycytidine; Docetaxel; Drug Resistance, Neoplasm; Drug Synergism; Equilibrative Nucleoside Transporter 1; Gemcitabine; Gene Expression Regulation, Neoplastic; HCT116 Cells; HT29 Cells; Humans; Inhibitory Concentration 50; Molecular Structure; Neoplasms; Reverse Transcriptase Polymerase Chain Reaction; Taxoids | 2007 |
Repair of 2'-C-cyano-2'-deoxy-1-beta-D-arabino-pentofuranosylcytosine-induced DNA single-strand breaks by transcription-coupled nucleotide excision repair.
Topics: Animals; Antineoplastic Agents; Cell Line, Tumor; CHO Cells; Cricetinae; Cricetulus; Cytarabine; Cytosine; Dioxolanes; DNA Damage; DNA Repair; HeLa Cells; Humans; Mice; Transcription, Genetic; Tumor Suppressor Protein p53 | 2008 |
Discovery of a new template for anticancer agents: 2'-deoxy-2'-fluoro-4'-selenoarabinofuranosyl-cytosine (2'-F-4'-seleno-ara-C).
Topics: Antineoplastic Agents; Cell Line, Tumor; Cytarabine; Cytosine; Drug Discovery; Halogenation; Humans; Inhibitory Concentration 50; Models, Molecular; Molecular Conformation; Organoselenium Compounds | 2009 |
Human adenovirus replication in immunocompetent Syrian hamsters can be attenuated with chlorpromazine or cidofovir.
Topics: Adenoviridae Infections; Adenoviruses, Human; Animals; Biological Transport; Cell Death; Cell Line; Cell Line, Tumor; Cell Nucleus; Chlorpromazine; Cidofovir; Cricetinae; Cytarabine; Cytosine; Humans; Immunocompetence; Mesocricetus; Neoplasms; Organ Specificity; Organophosphonates; Transduction, Genetic; Virus Replication | 2010 |
Progressive multifocal leucoencephalopathy in a patient with Sézary syndrome.
Topics: Antiviral Agents; CD4-Positive T-Lymphocytes; Cidofovir; Cytarabine; Cytosine; Fatal Outcome; Flow Cytometry; Humans; JC Virus; Leukoencephalopathy, Progressive Multifocal; Male; Middle Aged; Organophosphonates; Receptors, Antigen, T-Cell, alpha-beta; Sezary Syndrome; Skin Neoplasms | 2010 |
Early lymphocyte recovery after intensive timed sequential chemotherapy for acute myelogenous leukemia: peripheral oligoclonal expansion of regulatory T cells.
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Cell Separation; Cytarabine; Cytosine; Daunorubicin; Etoposide; Female; Flavonoids; Flow Cytometry; Gene Expression Profiling; Humans; Immunophenotyping; Leukemia, Myeloid, Acute; Male; Middle Aged; Mitoxantrone; Piperidines; Reverse Transcriptase Polymerase Chain Reaction; T-Lymphocyte Subsets; T-Lymphocytes, Regulatory; Vidarabine; Young Adult | 2011 |
Treatment of progressive multifocal leukoencephalopathy and idiopathic CD4+ lymphocytopenia.
Topics: Antiviral Agents; CD4 Lymphocyte Count; Cidofovir; Cytarabine; Cytokines; Cytosine; Humans; JC Virus; Leukoencephalopathy, Progressive Multifocal; Male; Middle Aged; Organophosphonates; Randomized Controlled Trials as Topic; T-Lymphocytopenia, Idiopathic CD4-Positive; Treatment Outcome | 2010 |
Activities of different classes of acyclic nucleoside phosphonates against BK virus in primary human renal cells.
Topics: BK Virus; Cell Line; Cell Proliferation; Cidofovir; Cytarabine; Cytosine; Humans; Isoxazoles; Kidney; Leflunomide; Nucleosides; Organophosphonates; Polymerase Chain Reaction; Vidarabine | 2011 |
Applicability of a "Pick a Winner" trial design to acute myeloid leukemia.
Topics: Adenine Nucleotides; Aged; Aminoglycosides; Antibodies, Monoclonal; Antibodies, Monoclonal, Humanized; Antineoplastic Combined Chemotherapy Protocols; Arabinonucleosides; Arsenic Trioxide; Arsenicals; Clinical Trials, Phase III as Topic; Clofarabine; Cost-Benefit Analysis; Cytarabine; Cytosine; Drug Discovery; Early Termination of Clinical Trials; Follow-Up Studies; Gemtuzumab; Humans; Leukemia, Myeloid, Acute; Middle Aged; Multicenter Studies as Topic; Oxides; Patient Selection; Quality-Adjusted Life Years; Quinolones; Randomized Controlled Trials as Topic; Research Design; Sample Size; Software Design; Treatment Outcome; United Kingdom | 2011 |
Stratification of nucleoside analog chemotherapy using 1-(2'-deoxy-2'-18F-fluoro-β-D-arabinofuranosyl)cytosine and 1-(2'-deoxy-2'-18F-fluoro-β-L-arabinofuranosyl)-5-methylcytosine PET.
Topics: Adenine Nucleotides; Animals; Arabinonucleosides; Cell Line, Tumor; Clofarabine; Cytarabine; Cytidine Deaminase; Cytosine; Deoxycytidine; Deoxycytidine Kinase; Fluorine Radioisotopes; Gemcitabine; Gene Expression Regulation, Neoplastic; Leukemia, Lymphoid; Mice; Positron-Emission Tomography; Treatment Outcome | 2012 |
Chirality effects on the IRMPD spectra of basket resorcinarene/nucleoside complexes.
Topics: Cytarabine; Cytidine; Cytosine; Molecular Structure; Nucleosides; Protons; Spectrophotometry, Infrared; Stereoisomerism | 2012 |
Sapacitabine, the prodrug of CNDAC, is a nucleoside analog with a unique action mechanism of inducing DNA strand breaks.
Topics: Animals; Antimetabolites, Antineoplastic; Arabinonucleosides; CHO Cells; Cricetinae; Cricetulus; Cytarabine; Cytosine; Deoxycytidine; DNA Breaks, Double-Stranded; DNA Repair; DNA-Binding Proteins; Gemcitabine; Homologous Recombination; Inhibitory Concentration 50; Prodrugs | 2012 |
TDP1 is Critical for the Repair of DNA Breaks Induced by Sapacitabine, a Nucleoside also Targeting ATM- and BRCA-Deficient Tumors.
Topics: Arabinonucleosides; BRCA2 Protein; Camptothecin; Colorectal Neoplasms; Cytarabine; Cytosine; DNA Breaks, Single-Stranded; DNA Damage; DNA Repair; DNA Replication; Gene Expression Regulation, Neoplastic; HCT116 Cells; Humans; Phosphoric Diester Hydrolases; Poly (ADP-Ribose) Polymerase-1 | 2017 |