cytarabine and cytidine

cytarabine has been researched along with cytidine in 83 studies

Research

Studies (83)

TimeframeStudies, this research(%)All Research%
pre-199044 (53.01)18.7374
1990's15 (18.07)18.2507
2000's15 (18.07)29.6817
2010's7 (8.43)24.3611
2020's2 (2.41)2.80

Authors

AuthorsStudies
Avery, TL; Chwang, TL; Fridland, A1
Guinan, M; Huang, N; Miller, GJ; Smith, M1
Karon, M; Lee, T; Monparler, RL1
Anderson, JE; Giblett, ER; Teng, YS1
Alwine, JC; Reed, SI; Stark, GR1
Mak, TW; Wan, CW1
Krajewska, E; Shugar, D1
Laliberté, J; Marquez, VE; Momparler, RL1
Balzarini, J; De Clercq, E; Neyts, J; Snoeck, R1
De Clercq, E; Marquez, VE; Murase, J1
Allegra, CJ; Grem, JL1
Balázová, E; Novotný, L; Rauko, P; Reichelová, V1
Mejer, J1
Allegra, CJ; Chabner, BA; Chu, E; Grem, JL; Johnson, P; Yeh, GC1
Grem, JL; Harrison, SD; Hawkins, MJ; Plowman, J; Rubinstein, L1
Novotný, L; Vachálková, A1
Cory, JG; Matsumoto, M; Rey, DA1
Broder, S; Mitsuya, H; Webb, TR1
Datta, G; Gurnani, S; Hosur, RV; Khetrapal, CL; Verma, NC1
Mejer, J; Mortensen, BT1
Guschlbauer, W; Hay, J; Jamieson, AT; Mengel, R; Wohlrab, F1
Arnett, G; Coburn, WC; O'Dell, CA; Riordan, JM; Shannon, WM; Shealy, YF; Thorpe, MC1
Chou, TC; Fanucchi, MP; Fox, JJ; Watanabe, KA1
Akerblom, L; Reichard, P1
Benedict, WF; Karon, M1
Burchenal, JH; Carter, SK1
Chabner, BA; Drake, JC; Johns, DG1
Hosono, H; Kuno, S1
Hamada, F; Hikita, J; Hirayama, H; Kanai, T; Sugihara, T1
LePage, GA; Nakai, Y1
Ganeshaguru, K; Hoffbrand, AV; Tattersall, MH1
DeYoung, JL; Feller, DR; Notari, RE1
Loehr, EV; Roberts, D1
Tattersall, MH1
Berger, AE; Kuentzel, SL; Neil, GL1
Cox, RP; Malathi, VG; Meyers, R; Silber, R1
Hoshi, A; Iigo, M; Kuretani, K; Saneyoshi, M1
Nagyvary, J; Pollard, DR1
Remin, M; Shugar, D1
Hamamura, EK; Moffatt, JG; Prystasz, M; Russell, AF; Verheyden, JP1
Ichino, M; Kikugawa, K1
Cass, CE; Paterson, AR1
Hoshi, A; Kanzawa, F; Kuretani, K1
Abbott, BJ; Baratta, MC; Greenberg, NH; Kline, I; Venditti, JM1
Arai, Y; Hoshi, A; Kanazawa, F; Kuretani, K; Saneyoshi, M1
Brown, RK; Hudson, RA; Lieu, TS; White, BC1
Burke, PJ; Steuart, CD1
Brent, TP; Krygier, V; Labitan, A; Momparler, RL1
Jones, PA; Taylor, SM1
Evans, WE; Sinkule, JA1
Beránk, J; Farghali, H; Janků, I; Novotný, L; Ryba, M1
Cysyk, RL; Hoerauf, RM; Karle, JM1
Goz, B; Orr, C; Wharton, W1
Chen, TS1
Grindey, GB; Kinahan, JJ; Kowal, EP1
Novotný, L; Pískala, A; Vachálková, A1
Cubitt, S; Enns, L; Hirani-Hojatti, S; Karimian, K; Mirzayans, R; Murthy, K; Paterson, MC; Radatus, B1
Bocek, P; Havel, J; Kostálová, A; Krivánková, L; Vargas, G1
Esche, H; Hoppe, H; Kirch, HC; Schröder, J; Schütte, J; Seeber, S1
Bachratá, M; Bílková, J; Novotný, L; Rauko, P; Stankovicová, M1
Hohl, RJ; Jung, KY; Wiemer, AJ; Wiemer, DF1
Kodama, T; Matsuda, A; Nomura, M; Shuto, S1
Brinkman, J; Evers, LM; Leen, R; Van Gennip, AH; Van Kuilenburg, AB; Verschuur, AC; Vet, RJ; Voûte, PA1
Leen, R; van Gennip, AH; van Kuilenburg, AB; Verschuur, AC; Voûte, PA1
Brinkman, J; Leen, R; Van Gennip, AH; Van Kuilenburg, AB; Verschuur, AC; Voûte, PA1
Bierau, J; Caron, HN; Helleman, J; Leen, R; Van Gennip, AH; Van Kuilenburg, AB1
Chen, X; Hohl, RJ; Wiemer, AJ; Wiemer, DF1
Chen, X; Wiemer, DF2
Ballmer-Hofer, K; Langer-Machova, Z; Marty, C; Schott, H; Schwendener, RA; Sigrist, S1
Ailenberg, M; Goldenberg, NM; Silverman, M1
Cass, CE; Clarke, ML; Damaraju, VL; Lang, T; Mowles, D; Smith, KM; Tackaberry, T; Tomkinson, B; Young, JD; Zhang, J1
Fujimoto, S; Hotta, A; Koma, M; Nagai, K; Nagasawa, K1
Endo, Y; Fukushima, M; Ito, M; Murata, D; Natsume, N; Obata, T; Sakamoto, K; Sasaki, T; Yamada, Y; Yamasaki, Y1
Bernhaus, A; Erker, T; Fritzer-Szekeres, M; Graser, G; Grusch, M; Handler, N; Horvath, Z; Jaeger, W; Jaschke, M; Krupitza, G; Lackner, A; Madlener, S; Ozsvar-Kozma, M; Saiko, P; Szekeres, T1
Botta, B; Calcaterra, A; D'Acquarica, I; Filippi, A; Fraschetti, C; Piccirillo, S; Rondino, F; Speranza, M1
Chan, K; Covey, J; Ebrahem, Q; Engelke, KJ; Gu, X; Jankowska, A; Ling, Y; Maciejewski, J; Mahfouz, RZ; Radivoyevitch, T; Saunthararajah, Y; Sekeres, MA; Tabarroki, A; Terse, P; Tiu, R; Visconte, V1
Terui, Y1
Beard, BC; Black, ME; Qiu, S; Ruan, H1
Abrous, DN; André, C; Castellanos-Jankiewicz, A; Clark, S; Cota, D; Guzman-Quevedo, O; Ladeveze, E; Laye, S; Leste-Lasserre, T; Nadjar, A; Rémus-Borel, J; Rey, C1
Abou Assi, H; Damha, MJ; González, C; Lin, YC; Serrano, I1
Aggarwal, AK; Buku, A; Choudhury, JR; Prakash, L; Prakash, S; Rechkoblit, O1
Israel, E; Rodgers, MT; Seidu, YS1

Reviews

3 review(s) available for cytarabine and cytidine

ArticleYear
Antimetabolites.
    Cancer chemotherapy and biological response modifiers, 1991, Volume: 12

    Topics: Animals; Antimetabolites; Antineoplastic Agents; Cytarabine; Cytidine; Drug Interactions; Drug Resistance; Floxuridine; Fluorouracil; Folic Acid Antagonists; Humans; Methotrexate; Neoplasms

1991
New cancer chemotherapeutic agents.
    Cancer, 1972, Volume: 30, Issue:6

    Topics: Aldehydes; Amides; Amines; Animals; Antineoplastic Agents; Asparaginase; Azacitidine; Azaguanine; Bleomycin; Carmustine; Chlorides; Cyclization; Cyclohexanes; Cytarabine; Cytidine; Doxorubicin; Glycosides; Humans; Hydroxyurea; Imidazoles; Leukemia, Lymphoid; Leukemia, Myeloid; Mice; Nitrosourea Compounds; Picolinic Acids; Platinum; Podophyllotoxin; Streptozocin; Thiosemicarbazones; Triazenes

1972
The emergence of drug resistance in tumours: a characteristic which may be exploited therapeutically.
    British journal of cancer, 1973, Volume: 27, Issue:5

    Topics: Aminohydrolases; Animals; Cytarabine; Cytidine; DNA; Drug Resistance; Humans; Leukemia; Leukemia L1210; Methotrexate; Neoplasms

1973

Other Studies

80 other study(ies) available for cytarabine and cytidine

ArticleYear
2'-O-nitro-1-beta-D-arabinofuranosylcytosine. A new derivative of 1-beta-D-arabinofuranosylcytosine that resists enzymatic deamination and has antileukemic activity.
    Journal of medicinal chemistry, 1983, Volume: 26, Issue:2

    Topics: Animals; Antimetabolites, Antineoplastic; Cytarabine; Drug Evaluation, Preclinical; Female; Leukemia L1210; Mice; Mice, Inbred Strains

1983
Design, chemical synthesis and antiviral evaluation of 2'-deoxy-2'-fluoro-2'-C-methyl-4'-thionucleosides.
    Bioorganic & medicinal chemistry letters, 2022, 04-01, Volume: 61

    Topics: Antiviral Agents; Dose-Response Relationship, Drug; Drug Design; Hepacivirus; Microbial Sensitivity Tests; Molecular Structure; Structure-Activity Relationship; Thionucleosides; Virus Replication

2022
Cellular phosphorylation of 1-beta-D-arabinofuranosylcytosine 5-azacytidine with intact fibrosarcoma and leukemic cells.
    Cancer research, 1975, Volume: 35, Issue:9

    Topics: Animals; Azacitidine; Binding, Competitive; Cells, Cultured; Cricetinae; Cytarabine; Cytidine; Deoxycytidine; Drug Resistance; Fibrosarcoma; Kinetics; Leukemia, Experimental; Mice; Phosphorus; Sarcoma, Experimental

1975
Cytidine deaminase: a new genetic polymorphism demonstrated in human granulocytes.
    American journal of human genetics, 1975, Volume: 27, Issue:4

    Topics: Azacitidine; Cytarabine; Cytidine; Cytidine Deaminase; Cytosine; Electrophoresis, Starch Gel; Female; Granulocytes; Humans; Leukocytes; Male; Nucleoside Deaminases; Pedigree; Phenotype; Polymorphism, Genetic

1975
Characterization of the autoregulation of simian virus 40 gene A.
    Journal of virology, 1977, Volume: 24, Issue:1

    Topics: Azides; Cell Line; Cytarabine; Cytidine; DNA Replication; DNA, Viral; Genes, Viral; Mutation; RNA, Viral; Simian virus 40; Temperature; Transcription, Genetic; Viral Proteins

1977
Deoxycytidine kinase and cytosine nucleoside deaminase activities in synchronized cultures of normal rat kidney cells.
    Cancer research, 1978, Volume: 38, Issue:9

    Topics: Cell Cycle; Cell Survival; Cells, Cultured; Cytarabine; Cytidine; Cytosine; Deoxycytidine; Nucleoside Deaminases; Phosphotransferases; Substrate Specificity

1978
Alkylated cytosine nucleosides: substrate and inhibitor properties in enzymatic deamination.
    Acta biochimica Polonica, 1975, Volume: 22, Issue:2

    Topics: Alkylation; Chemical Phenomena; Chemistry; Chromatography; Chromatography, Paper; Cytarabine; Cytidine; Cytidine Deaminase; Deoxycytidine; Kinetics; Nucleoside Deaminases; Pyrimidines; Salmonella typhimurium

1975
Potent inhibitors for the deamination of cytosine arabinoside and 5-aza-2'-deoxycytidine by human cytidine deaminase.
    Cancer chemotherapy and pharmacology, 1992, Volume: 30, Issue:1

    Topics: Antineoplastic Agents; Azacitidine; Azepines; Cytarabine; Cytidine; Cytidine Deaminase; Deamination; Decitabine; Humans; Kinetics; Pyrimidine Nucleosides; Tetrahydrouridine

1992
Particular characteristics of the anti-human cytomegalovirus activity of (S)-1-(3-hydroxy-2-phosphonylmethoxypropyl)cytosine (HPMPC) in vitro.
    Antiviral research, 1991, Volume: 16, Issue:1

    Topics: Animals; Antiviral Agents; Cidofovir; Cytarabine; Cytidine; Cytomegalovirus; Cytosine; Deoxycytidine; DNA, Viral; Ganciclovir; Humans; Organophosphonates; Organophosphorus Compounds; Tumor Cells, Cultured; Virus Replication

1991
Broad-spectrum antiviral and cytocidal activity of cyclopentenylcytosine, a carbocyclic nucleoside targeted at CTP synthetase.
    Biochemical pharmacology, 1991, Jun-15, Volume: 41, Issue:12

    Topics: Adenosine; Amides; Antiviral Agents; Azauridine; Carbon-Nitrogen Ligases; Cell Division; Cytarabine; Cytidine; Deoxycytidine; Drug Synergism; Fluorouracil; HeLa Cells; Humans; Ligases; Nucleosides; Pyrazoles; Ribavirin; Ribonucleosides; Ribose; Thymidine; Tumor Cells, Cultured; Uracil; Virus Replication; Viruses

1991
Sequence-dependent interaction of 5-fluorouracil and arabinosyl-5-azacytosine or 1-beta-D-arabinofuranosylcytosine.
    Biochemical pharmacology, 1991, Jul-05, Volume: 42, Issue:2

    Topics: Antineoplastic Combined Chemotherapy Protocols; Azacitidine; Cell Division; Cell Line; Cell Nucleus; Cell Survival; Colonic Neoplasms; Cytarabine; Cytidine; Deoxycytosine Nucleotides; DNA, Neoplasm; Drug Administration Schedule; Drug Interactions; Fluorouracil; Humans; Nucleic Acids; Thymine Nucleotides; Tumor Stem Cell Assay

1991
Evaluation of synergism of drugs cis-diamminedichloroplatinum (II) and arabinosylcytosine on the level of chemical interaction with DNA and on the growth of mouse leukemia.
    General pharmacology, 1991, Volume: 22, Issue:5

    Topics: Animals; Cisplatin; Cytarabine; Cytidine; DNA, Neoplasm; Drug Synergism; Female; Fluorescent Dyes; Leukemia L1210; Male; Mice; Mice, Inbred DBA; Spectrophotometry, Ultraviolet

1991
The impact of selected nucleosides on the cytotoxicity of Ara-C in HL60 cells.
    Advances in experimental medicine and biology, 1991, Volume: 309A

    Topics: Cell Line; Cell Survival; Cytarabine; Cytidine; Deoxyadenosines; Deoxycytidine; Deoxyguanosine; Drug Interactions; Humans; Kinetics; Leukemia, Promyelocytic, Acute; Nucleosides; Tetrahydrouridine; Uridine

1991
Modulation of cytosine arabinoside toxicity by 3-deazauridine in a murine leukemia model.
    Leukemia research, 1991, Volume: 15, Issue:4

    Topics: 3-Deazauridine; Animals; Antineoplastic Combined Chemotherapy Protocols; Cytarabine; Cytidine; Drug Resistance; Drug Synergism; Female; Leukemia L1210; Male; Mice; Mice, Inbred Strains; Remission Induction; Survival Rate

1991
Some electrochemical characteristics of synthetic analogs of nucleic acid components. I. Derivatives of cytidine and arabinosylcytosine. An attempt to find correlation among some of their properties.
    Neoplasma, 1990, Volume: 37, Issue:4

    Topics: Cytarabine; Cytidine; DNA; Oxidation-Reduction; Polarography; Pyrimidine Nucleosides; Solubility

1990
Effects of cytosine arabinoside and hydroxyurea on the synthesis of deoxyribonucleotides and DNA replication in L1210 cells.
    Advances in enzyme regulation, 1990, Volume: 30

    Topics: Adenosine; Animals; Cytarabine; Cytidine; Deoxyribonucleotides; DNA Replication; Hydroxyurea; Leukemia L1210; Mice; RNA, Neoplasm; Tumor Cells, Cultured

1990
1-(2,3-Anhydro-beta-D-lyxofuranosyl)cytosine derivatives as potential inhibitors of the human immunodeficiency virus.
    Journal of medicinal chemistry, 1988, Volume: 31, Issue:7

    Topics: Ancitabine; Chemical Phenomena; Chemistry; Cytarabine; Cytidine; HIV; Magnetic Resonance Spectroscopy; Mass Spectrometry; Thymidine; Uracil; Zidovudine

1988
Mechanism of interaction of the antileukemic drug cytosine arabinoside with aromatic peptides: role of sugar conformation and peptide backbone.
    Physiological chemistry and physics and medical NMR, 1989, Volume: 21, Issue:4

    Topics: Amino Acid Sequence; Carbohydrate Conformation; Carbohydrates; Cytarabine; Cytidine; Cytosine; Magnetic Resonance Spectroscopy; Molecular Sequence Data; Peptides; Spectrometry, Fluorescence

1989
Reduction of ara-C cytotoxicity in HL 60 cells by addition of deoxycytidine, cytidine or increased level of cytidine deaminase.
    Advances in experimental medicine and biology, 1989, Volume: 253B

    Topics: Bone Marrow; Bone Marrow Cells; Cell Division; Cytarabine; Cytidine; Cytidine Deaminase; Deoxycytidine; Deoxycytidine Kinase; Humans; Leukemia, Promyelocytic, Acute; Nucleoside Deaminases; Phosphotransferases; Tetrahydrouridine; Tretinoin; Tumor Cells, Cultured

1989
The effect of 2'-fluoro-2'-deoxycytidine on herpes virus growth.
    Biochimica et biophysica acta, 1985, Mar-20, Volume: 824, Issue:3

    Topics: Animals; Cell Division; Cricetinae; Cytarabine; Cytidine; Deoxycytidine; Herpesvirus 1, Equid; Herpesvirus 1, Suid; Humans; Phosphorylation; Simplexvirus; Thymidine Kinase

1985
Carbocyclic analogues of 5-halocytosine nucleosides.
    Journal of medicinal chemistry, 1986, Volume: 29, Issue:9

    Topics: Bromodeoxycytidine; Chemical Phenomena; Chemistry; Cytarabine; Cytidine; Deoxycytidine; Halogens; Simplexvirus; Virus Replication

1986
Kinetics and substrate specificity of human and canine cytidine deaminase.
    Biochemical pharmacology, 1986, Apr-01, Volume: 35, Issue:7

    Topics: Animals; Arabinofuranosyluracil; Cytarabine; Cytidine; Cytidine Deaminase; Deoxycytidine; Dogs; Humans; Kinetics; Liver; Nucleoside Deaminases; Substrate Specificity

1986
Azidocytidine is a specific inhibitor of deoxyribonucleotide synthesis in 3T6 cells.
    The Journal of biological chemistry, 1985, Aug-05, Volume: 260, Issue:16

    Topics: Animals; Cell Division; Cells, Cultured; Cytarabine; Cytidine; Deoxyribonucleotides; DNA Replication; Fibroblasts; Hydroxyurea; Kinetics; Mice; Phosphorylation

1985
Chromatid breakage: differential effect of inhibitors of DNA synthesis during G 2 phase.
    Science (New York, N.Y.), 1972, Oct-06, Volume: 178, Issue:4056

    Topics: Animals; Azacitidine; Azaguanine; Cell Line; Chromatids; Chromosome Aberrations; Cricetinae; Cytarabine; Cytidine; DNA; DNA Nucleotidyltransferases; Hydroxyurea; Lung; Mitosis; Oxidoreductases; Pyridines; Ribonucleotides; Thiosemicarbazones; Triazines

1972
Deamination of 5-azacytidine by a human leukemia cell cytidine deaminase.
    Biochemical pharmacology, 1973, Nov-01, Volume: 22, Issue:21

    Topics: Aminohydrolases; Azacitidine; Blood Proteins; Carbon Radioisotopes; Chromatography, Ion Exchange; Cytarabine; Cytidine; Deamination; Humans; In Vitro Techniques; Kinetics; Leukemia, Myeloid; Leukocytes; Spectrophotometry, Ultraviolet

1973
The purification and properties of cytidine deaminase from Escherichia coli.
    Journal of biochemistry, 1973, Volume: 74, Issue:4

    Topics: Aminohydrolases; Chromatography; Cytarabine; Cytidine; Deamination; Deoxycytidine; Deoxyribonucleosides; Edetic Acid; Electrophoresis; Escherichia coli; Hydrogen-Ion Concentration; Metals; Molecular Weight; Pyrimidine Nucleosides; Ribonucleosides; Sulfhydryl Reagents; Urea

1973
Distribution and excretion of cyclocytidine in monkeys, dogs, and rats.
    Gan, 1974, Volume: 65, Issue:2

    Topics: Anhydrides; Animals; Arabinose; Cytarabine; Cytidine; Dogs; Feces; Half-Life; Haplorhini; Injections, Intravenous; Kidney; Liver; Macaca; Nucleosides; Rats; Uracil

1974
Characterization of the kinase(s) involved in the phosphorylation of - and -2'-deoxythioguanosine.
    Cancer research, 1972, Volume: 32, Issue:11

    Topics: Adenosine Triphosphate; Animals; Bone Marrow; Carcinoma, Hepatocellular; Cattle; Cell Line; Cell-Free System; Chromatography, DEAE-Cellulose; Cytarabine; Cytidine; Deoxyribonucleosides; Dithiothreitol; Guanosine; Humans; Isoenzymes; Kinetics; Leukemia L1210; Liver Neoplasms; Lymphoma, Non-Hodgkin; Magnesium; Mercaptopurine; Mice; Mice, Inbred AKR; Mice, Inbred BALB C; Mice, Inbred C3H; Mice, Inbred DBA; Phosphotransferases

1972
The mechanisms of action of three fluorine substituted cytosine analogs: implications for cancer chemotherapy.
    Biochemical pharmacology, 1974, Sep-15, Volume: 23, Issue:18

    Topics: Antineoplastic Agents; Arabinose; Cells, Cultured; Cytarabine; Cytidine; Cytosine; Deoxyuridine; DNA; Flucytosine; Fluorine; Humans; Lymphocytes; Nucleosides; Thymidine; Tritium

1974
Comparative reactivity of cytidine and arabinosylcytosine to their 6-methyl derivatives in the presence of cytidine deaminase.
    Research communications in chemical pathology and pharmacology, 1974, Volume: 9, Issue:1

    Topics: Aminohydrolases; Animals; Chemical Phenomena; Chemistry; Cytarabine; Cytidine; Drug Stability; Kidney; Kinetics; Nucleoside Deaminases; Spectrophotometry, Ultraviolet; Structure-Activity Relationship; Swine

1974
Depression of thymidylate synthetase activity in response to cytosine arabinoside.
    Cancer research, 1972, Volume: 32, Issue:6

    Topics: Carbon Isotopes; Cell Line; Cytarabine; Cytidine; DNA; Glycine; Humans; Hypoxanthines; In Vitro Techniques; Leukemia, Lymphoid; Leukocytes; Methyltransferases; Nucleic Acids; RNA; Thymidine; Thymine Nucleotides; Time Factors; Tritium; Uracil Nucleotides; Uridine

1972
A microbiological assay for cyclocytidine--disposition studies in mice.
    Research communications in chemical pathology and pharmacology, 1973, Volume: 5, Issue:3

    Topics: Animals; Biological Assay; Cytarabine; Cytidine; Deoxycytidine; Enterococcus faecalis; Female; Mice; Nucleosides; Uridine

1973
Studies on nucleoside deaminase. Increase in activity in HeLa cell cultures caused by cytosine arabinoside.
    The Journal of biological chemistry, 1973, Sep-10, Volume: 248, Issue:17

    Topics: Alkaline Phosphatase; Aminohydrolases; Antimetabolites; Carbon Isotopes; Cell Fractionation; Culture Media; Cycloheximide; Cytarabine; Cytidine; Deamination; DNA; DNA Nucleotidyltransferases; Glucosephosphate Dehydrogenase; HeLa Cells; L-Lactate Dehydrogenase; Leucine; Methotrexate; Nucleosides; Protein Biosynthesis; Thymidine; Time Factors; Tritium; Uridine

1973
Resistance of cyclocytidine to cytidine deaminase.
    Chemical & pharmaceutical bulletin, 1973, Volume: 21, Issue:7

    Topics: Aminohydrolases; Anhydrides; Animals; Antineoplastic Agents; Cytarabine; Cytidine; Deamination; In Vitro Techniques; Kidney; Mice

1973
Inhibition of pancreatic ribonuclease A by arabinonucleotides.
    Biochemistry, 1973, Mar-13, Volume: 12, Issue:6

    Topics: Animals; Arabinose; Cattle; Chromatography, Paper; Cytarabine; Cytidine; Cytosine Nucleotides; Kinetics; Nucleosides; Nucleotides; Oligonucleotides; Pancreas; Phosphoric Acids; Photometry; Ribonucleases; Ribose; Spectrophotometry, Ultraviolet; Structure-Activity Relationship; Uracil Nucleotides; Uridine

1973
Conformational analysis of cytidine, 1-beta-D-(arabinofuranosyl)cytosine and their O'-methyl derivatives by proton magnetic resonance spectroscopy.
    Journal of the American Chemical Society, 1973, Nov-28, Volume: 95, Issue:24

    Topics: Computers; Cytarabine; Cytidine; Magnetic Resonance Spectroscopy; Methods; Methylation; Molecular Conformation; Structure-Activity Relationship

1973
Reactions of 2-acyloxyisobutyryl halides with nucleosides. V. Reactions with cytidine and its derivatives;.
    The Journal of organic chemistry, 1974, Jul-26, Volume: 39, Issue:15

    Topics: Anhydrides; Cytarabine; Cytidine; Hydrolysis; Magnetic Resonance Spectroscopy; Temperature

1974
Studies on the Vilsmeier-Haack reaction. IV. Convenient synthesis of 2,2'-anhydro-1- -D-arabinofuranosylcytosine (2,2'-cyclocytidine) and its derivatives.
    The Journal of organic chemistry, 1972, Jan-28, Volume: 37, Issue:2

    Topics: Antineoplastic Agents; Chemical Phenomena; Chemistry; Chromatography, Paper; Cyclization; Cytarabine; Cytidine; Methods; Nucleosides

1972
Mediated transport of nucleosides in human erythrocytes. Accelerative exchange diffusion of uridine and thymidine and specificity toward pyrimidine nucleosides as permeants.
    The Journal of biological chemistry, 1972, May-25, Volume: 247, Issue:10

    Topics: Benzyl Compounds; Biological Transport; Carbon Isotopes; Cytarabine; Cytidine; Deoxyribonucleosides; Diffusion; Erythrocytes; Guanosine; Humans; Kinetics; Nitro Compounds; Ribonucleosides; Structure-Activity Relationship; Sulfides; Thymidine; Uridine

1972
Antitumor activity of cyclocytidine in a variety of tumors.
    Gan, 1972, Volume: 63, Issue:3

    Topics: Adenocarcinoma; Animals; Antineoplastic Agents; Carcinoma, Ehrlich Tumor; Cell Line; Cyclization; Cyclophosphamide; Cytarabine; Cytidine; Dose-Response Relationship, Drug; Female; Fluorouracil; Leukemia L1210; Leukemia, Experimental; Male; Mercaptopurine; Methotrexate; Mice; Mitomycins; Neoplasms, Experimental; Sarcoma 180

1972
Studies of the L1210 antileukemic activity of O-2,2'-cyclocytidine, monoacetate (anhydro-ara-C; NSC-129220)--comparison with cytosine arabinoside (NSC-63878) with respect to treatment schedule dependency.
    Cancer chemotherapy reports, 1972, Volume: 56, Issue:4

    Topics: Acetates; Administration, Oral; Animals; Cyclization; Cytarabine; Cytidine; Drug Resistance; Injections, Intraperitoneal; Injections, Subcutaneous; Leukemia L1210; Male; Mice; Mice, Inbred Strains

1972
2,2'-O-cyclocytidine, an antitumor cytidine analog resistant to cytidine deaminase.
    Gan, 1971, Volume: 62, Issue:2

    Topics: Aminohydrolases; Animals; Antineoplastic Agents; Chemical Phenomena; Chemistry; Cytarabine; Cytidine; Injections, Intraperitoneal; Leukemia L1210; Mice

1971
Transport of pyrimidine nucleosides across human erythrocyte membranes.
    Biochimica et biophysica acta, 1971, Sep-14, Volume: 241, Issue:3

    Topics: ABO Blood-Group System; Biological Transport; Carbon Isotopes; Cell Membrane; Cytarabine; Cytidine; Depression, Chemical; Erythrocytes; Humans; Inosine; Kinetics; Purines; Sucrose; Thymidine; Tritium; Uridine

1971
Cytidine deaminase and the development of resistance to arabinosyl cytosine.
    Nature: New biology, 1971, Sep-22, Volume: 233, Issue:38

    Topics: Adult; Aminohydrolases; Bone Marrow; Bone Marrow Cells; Carbon Isotopes; Cyclophosphamide; Cytarabine; Cytidine; Drug Resistance; Humans; Leukemia; Leukemia, Lymphoid; Leukemia, Myeloid, Acute; Spectrum Analysis; Time Factors

1971
Studies on the phosphorylation of cytosine arabinoside in mammalian cells.
    Molecular pharmacology, 1971, Volume: 7, Issue:4

    Topics: Cells, Cultured; Cytarabine; Cytidine; Cytosine Nucleotides; Deoxyadenosines; Feedback; HeLa Cells; Kinetics; Oxidative Phosphorylation; Phosphotransferases; Tritium

1971
Cellular differentiation, cytidine analogs and DNA methylation.
    Cell, 1980, Volume: 20, Issue:1

    Topics: Adipose Tissue; Animals; Azacitidine; Cell Differentiation; Cells, Cultured; Cytarabine; Cytidine; Decitabine; Deoxycytidine; DNA; DNA (Cytosine-5-)-Methyltransferases; Methylation; Methyltransferases; Mice; Muscles; Structure-Activity Relationship

1980
High-performance liquid chromatographic assay for cytosine arabinoside, uracil arabinoside and some related nucleosides.
    Journal of chromatography, 1983, May-13, Volume: 274

    Topics: Arabinofuranosyluracil; Child; Chromatography, High Pressure Liquid; Cytarabine; Cytidine; Deoxycytidine; Humans; Infusions, Parenteral; Kinetics; Leukemia, Myeloid, Acute; Uridine

1983
Kinetics of transport and metabolism of 1-beta-D-arabinofuranosylcytosine and structural analogs by everted perfused rat jejunum.
    Biochemical pharmacology, 1984, Feb-15, Volume: 33, Issue:4

    Topics: Animals; Biological Transport; Biotransformation; Cytarabine; Cytidine; In Vitro Techniques; Intestinal Mucosa; Jejunum; Kinetics; Male; Perfusion; Rats; Rats, Inbred Strains; Structure-Activity Relationship

1984
Labelling of the thymidine and deoxycytidine bases of DNA by [2-14C]deoxycytidine in cultured L1210 cells.
    Cancer letters, 1983, Volume: 19, Issue:2

    Topics: 3-Deazauridine; Animals; Carbon Radioisotopes; Cytarabine; Cytidine; Deoxycytidine; DNA; Leukemia L1210; Mice; Tetrahydrouridine; Thymidine

1983
Inhibition by deoxycytidine, cytidine, and beta-cytosine arabinoside of the induction of alkaline phosphatase activity in HeLa cells.
    Journal of the National Cancer Institute, 1980, Volume: 64, Issue:6

    Topics: Alkaline Phosphatase; Cytarabine; Cytidine; Deoxycytidine; DNA; Enzyme Induction; HeLa Cells; Hot Temperature; Humans; Idoxuridine; Kinetics

1980
Effects of arabinosyl cytosine and 5-azacytidine on the intestinal absorption of nutrients.
    Toxicology and applied pharmacology, 1982, Volume: 62, Issue:1

    Topics: Amino Acids; Animals; Cytarabine; Cytidine; Deoxycytidine; Electrolytes; Glucose; Intestinal Absorption; Male; Mice; Mice, Inbred Strains

1982
Biochemical and antitumor effects of the combination of thymidine and 1-beta-D-arabinofuranosylcytosine against leukemia L1210.
    Cancer research, 1981, Volume: 41, Issue:2

    Topics: Animals; Arabinofuranosylcytosine Triphosphate; Aspartic Acid; Cells, Cultured; Cytarabine; Cytidine; Drug Therapy, Combination; Leukemia L1210; Mice; Phosphonoacetic Acid; Thymidine

1981
Polarographic reduction and carcinogenic index tg alpha of 5-aza nucleosides possessing antileukemic activity.
    Neoplasma, 1993, Volume: 40, Issue:5

    Topics: Antineoplastic Agents; Azacitidine; Carcinogens; Cytarabine; Cytidine; Molecular Structure; Oxidation-Reduction; Polarography; Structure-Activity Relationship

1993
Comparative genotoxicity of 2,3'-O-cyclocytidine, beta-xylocytidine and 1-beta-D-arabinofuranosylcytosine in human tumor cell lines.
    Carcinogenesis, 1994, Volume: 15, Issue:10

    Topics: Ancitabine; Antineoplastic Combined Chemotherapy Protocols; Cell Division; Cell Survival; Child; Cytarabine; Cytidine; DNA Damage; DNA Repair; DNA Replication; DNA, Neoplasm; Drug Screening Assays, Antitumor; Drug Synergism; Humans; Leukemia; Neoplasms; Tumor Cells, Cultured

1994
Separation of aracytidine and cytidine by capillary electrophoretic techniques.
    Electrophoresis, 1996, Volume: 17, Issue:12

    Topics: Boric Acids; Cytarabine; Cytidine; Electrolytes; Electrophoresis, Capillary; Humans; Hydrogen-Ion Concentration; Micelles; Sodium Dodecyl Sulfate

1996
Recombinant gene products of two natural variants of the human cytidine deaminase gene confer different deamination rates of cytarabine in vitro.
    Experimental hematology, 1998, Volume: 26, Issue:5

    Topics: Cytarabine; Cytidine; Cytidine Deaminase; Deamination; DNA, Complementary; Drug Resistance, Neoplasm; Genetic Variation; Humans; Recombinant Proteins; Sequence Analysis, DNA

1998
Transformation kinetics of the 5'-chloro-5'-deoxy analogue of arabinosylcytosine.
    Neoplasma, 1999, Volume: 46, Issue:3

    Topics: Antineoplastic Agents; Cytarabine; Cytidine; Cytosine; Drug Stability; Hydrogen-Ion Concentration; Kinetics; Structure-Activity Relationship; Thermodynamics

1999
Synthesis of phosphonate derivatives of uridine, cytidine, and cytosine arabinoside.
    Bioorganic & medicinal chemistry, 2000, Volume: 8, Issue:10

    Topics: Antimetabolites, Antineoplastic; Chemistry, Organic; Cytarabine; Cytidine; Organic Chemistry Phenomena; Organophosphonates; Pyruvate Kinase; Uridine

2000
An efficient method for the preparation of 1'alpha-branched-chain sugar pyrimidine ribonucleosides from uridine: the first conversion of a natural nucleoside into 1'-substituted ribonucleosides.
    Chemistry (Weinheim an der Bergstrasse, Germany), 2001, Jun-01, Volume: 7, Issue:11

    Topics: Cyclization; Cytarabine; Cytidine; Deoxycytidine; Glycosylation; Molecular Structure; Organoselenium Compounds; Pyrimidine Nucleosides; Ribonucleosides; Selenium; Silicon; Stereoisomerism; Structure-Activity Relationship; Uridine; Vinyl Compounds

2001
Cyclopentenyl cytosine induces apoptosis and increases cytarabine-induced apoptosis in a T-lymphoblastic leukemic cell-line.
    Leukemia research, 2001, Volume: 25, Issue:10

    Topics: Annexin A5; Antimetabolites, Antineoplastic; Antineoplastic Agents; Apoptosis; Cell Division; Cytarabine; Cytidine; Dose-Response Relationship, Drug; Drug Synergism; Humans; Leukemia, T-Cell; Necrosis; Tumor Cells, Cultured

2001
Cyclopentenyl cytosine increases the phosphorylation and incorporation into dna of arabinofu-ranosyl cytosine in a myeloid leukemic cell-line.
    Advances in experimental medicine and biology, 2000, Volume: 486

    Topics: Antimetabolites, Antineoplastic; Antineoplastic Agents; Carbon-Nitrogen Ligases; Cytarabine; Cytidine; Cytidine Diphosphate; Cytidine Monophosphate; Deoxycytosine Nucleotides; DNA; Dose-Response Relationship, Drug; Enzyme Inhibitors; HL-60 Cells; Humans; Leukemia, Myeloid; Phosphorylation

2000
Cyclopentenyl cytosine increases the phosphorylation and incorporation into DNA of 1-beta-D-arabinofuranosyl cytosine in a human T-lymphoblastic cell line.
    International journal of cancer, 2002, Apr-01, Volume: 98, Issue:4

    Topics: Antineoplastic Agents; Apoptosis; Cell Division; Cytarabine; Cytidine; Cytidine Triphosphate; Deoxycytosine Nucleotides; DNA; Dose-Response Relationship, Drug; Drug Resistance, Neoplasm; Humans; Phosphorylation; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Time Factors; Tumor Cells, Cultured

2002
Cyclopentenyl cytosine primes SK-N-BE(2)c neuroblastoma cells for cytarabine toxicity.
    International journal of cancer, 2003, Jan-20, Volume: 103, Issue:3

    Topics: Antimetabolites, Antineoplastic; Apoptosis; Carbon-Nitrogen Ligases; Cell Cycle; Cell Division; Cytarabine; Cytidine; DNA, Neoplasm; Dose-Response Relationship, Drug; Drug Resistance, Neoplasm; Drug Synergism; Enzyme Inhibitors; Humans; Neuroblastoma; Phosphorylation; Tumor Cells, Cultured

2003
Stereoselective synthesis of the 5'-hydroxy-5'-phosphonate derivatives of cytidine and cytosine arabinoside.
    The Journal of organic chemistry, 2002, Dec-27, Volume: 67, Issue:26

    Topics: Cytarabine; Cytidine; Drug Screening Assays, Antitumor; Humans; Hydrolysis; K562 Cells; Magnetic Resonance Spectroscopy; Molecular Structure; Organophosphonates; Stereoisomerism; Structure-Activity Relationship; Tumor Cells, Cultured

2002
Synthesis of 5'-amino-5'-phosphonate analogues of pyrimidine nucleoside monophosphates.
    The Journal of organic chemistry, 2003, Aug-08, Volume: 68, Issue:16

    Topics: Chromatography, Thin Layer; Cytarabine; Cytidine; Indicators and Reagents; Magnetic Resonance Spectroscopy; Organophosphonates; Oxidation-Reduction; Pyrimidine Nucleosides; Stereoisomerism; Uridine

2003
Alpha-phosphono lactone analogues of cytidine and cytosine arabinoside diphosphates: synthesis via ring closing metathesis.
    The Journal of organic chemistry, 2003, Aug-22, Volume: 68, Issue:17

    Topics: Arabinose; Cytarabine; Cytidine; Cytidine Diphosphate; Cytosine; Indicators and Reagents; Lactones; Models, Molecular; Organophosphonates; Stereoisomerism

2003
Isolation and characterization of a scFv antibody specific for tumor endothelial marker 1 (TEM1), a new reagent for targeted tumor therapy.
    Cancer letters, 2006, Apr-28, Volume: 235, Issue:2

    Topics: Antibody Specificity; Antigens, CD; Antigens, Neoplasm; Cell Line; Cytarabine; Cytidine; Humans; Immunoglobulin Fragments; Liposomes; Membrane Proteins; Neoplasm Proteins; Neoplasms; Peptide Library; Recombinant Proteins

2006
Description of a PCR-based technique for DNA splicing and mutagenesis by producing 5' overhangs with run through stop DNA synthesis utilizing Ara-C.
    BMC biotechnology, 2005, Sep-01, Volume: 5

    Topics: Alternative Splicing; Base Composition; Cloning, Molecular; Codon, Terminator; Cofilin 1; Cytarabine; Cytidine; DNA; DNA Mutational Analysis; DNA Primers; DNA Restriction Enzymes; DNA, Recombinant; Gene Deletion; Humans; Mutagenesis; Mutagenesis, Site-Directed; Nucleic Acid Conformation; Polymerase Chain Reaction; Sequence Analysis, DNA

2005
The role of human nucleoside transporters in cellular uptake of 4'-thio-beta-D-arabinofuranosylcytosine and beta-D-arabinosylcytosine.
    Molecular pharmacology, 2006, Volume: 70, Issue:1

    Topics: Animals; Arabinonucleosides; Biological Transport; Cell Line, Tumor; Cell Survival; Cytarabine; Cytidine; Dose-Response Relationship, Drug; Equilibrative-Nucleoside Transporter 2; Female; HeLa Cells; Humans; Membrane Potentials; Nucleoside Transport Proteins; Oocytes; Saccharomyces cerevisiae; Thioinosine; Transfection; Tritium; Uridine; Xenopus laevis

2006
Cytidine is a novel substrate for wild-type concentrative nucleoside transporter 2.
    Biochemical and biophysical research communications, 2006, Aug-25, Volume: 347, Issue:2

    Topics: Amino Acid Substitution; Animals; Antimetabolites, Antineoplastic; Biological Transport; Chlorocebus aethiops; COS Cells; Cytarabine; Cytidine; Deoxycytidine; Dose-Response Relationship, Drug; Gemcitabine; Genotype; Kinetics; Male; Membrane Transport Proteins; Mice; Thymidine; Transfection; Tritium; Uridine

2006
Cellular localization and functional characterization of the equilibrative nucleoside transporters of antitumor nucleosides.
    Cancer science, 2007, Volume: 98, Issue:10

    Topics: Antimetabolites, Antineoplastic; Biological Transport; Cell Membrane; Cell Proliferation; Cytarabine; Cytidine; Equilibrative Nucleoside Transport Proteins; Equilibrative Nucleoside Transporter 1; Equilibrative-Nucleoside Transporter 2; Fibrosarcoma; Green Fluorescent Proteins; Humans; Nucleoside Transport Proteins; RNA, Messenger; Stomach Neoplasms; Tumor Cells, Cultured

2007
N-hydroxy-N'-(3,4,5-trimethoxyphenyl)-3,4,5-trimethoxy-benzamidine, a novel resveratrol analog, inhibits ribonucleotide reductase in HL-60 human promyelocytic leukemia cells: synergistic antitumor activity with arabinofuranosylcytosine.
    International journal of oncology, 2007, Volume: 31, Issue:5

    Topics: Antineoplastic Agents; Apoptosis; Cell Cycle; Cytarabine; Cytidine; Drug Synergism; Enzyme Inhibitors; HL-60 Cells; Humans; Resveratrol; Ribonucleotide Reductases; Stilbenes

2007
Chirality effects on the IRMPD spectra of basket resorcinarene/nucleoside complexes.
    Chemistry (Weinheim an der Bergstrasse, Germany), 2012, Jul-02, Volume: 18, Issue:27

    Topics: Cytarabine; Cytidine; Cytosine; Molecular Structure; Nucleosides; Protons; Spectrophotometry, Infrared; Stereoisomerism

2012
Increased CDA expression/activity in males contributes to decreased cytidine analog half-life and likely contributes to worse outcomes with 5-azacytidine or decitabine therapy.
    Clinical cancer research : an official journal of the American Association for Cancer Research, 2013, Feb-15, Volume: 19, Issue:4

    Topics: Animals; Azacitidine; Cytarabine; Cytidine; Cytidine Deaminase; Decitabine; DNA (Cytosine-5-)-Methyltransferase 1; DNA (Cytosine-5-)-Methyltransferases; Female; Gene Expression Regulation, Neoplastic; Humans; Leukemia, Myeloid, Acute; Male; Mice; Myelodysplastic Syndromes; Polymorphism, Single Nucleotide; Survival Analysis; Treatment Outcome

2013
[Cytidine].
    Nihon rinsho. Japanese journal of clinical medicine, 2015, Volume: 73 Suppl 2

    Topics: Antineoplastic Agents; Arabinonucleosides; Cytarabine; Cytidine; Deoxycytidine; Gemcitabine; Humans; Neoplasms

2015
Creation of zebularine-resistant human cytidine deaminase mutants to enhance the chemoprotection of hematopoietic stem cells.
    Protein engineering, design & selection : PEDS, 2016, Volume: 29, Issue:12

    Topics: Amino Acid Sequence; Cytarabine; Cytidine; Cytidine Deaminase; Drug Resistance; Escherichia coli; Hematopoietic Stem Cell Transplantation; Humans; Mutagenesis; Mutation; Protein Engineering

2016
Inhibiting Microglia Expansion Prevents Diet-Induced Hypothalamic and Peripheral Inflammation.
    Diabetes, 2017, Volume: 66, Issue:4

    Topics: Adiposity; Animals; Antimitotic Agents; Arabinonucleosides; Arcuate Nucleus of Hypothalamus; Body Weight; Cell Proliferation; Cytarabine; Cytidine; Diet, High-Fat; Eating; Hypothalamus; Inflammation; Interleukin-1beta; Leptin; Macrophages, Peritoneal; Male; Mice; Microglia; NF-kappa B; Obesity; Tumor Necrosis Factor-alpha; Weight Gain

2017
Probing Synergistic Effects of DNA Methylation and 2'-β-Fluorination on i-Motif Stability.
    Chemistry (Weinheim an der Bergstrasse, Germany), 2018, Jan-09, Volume: 24, Issue:2

    Topics: Cytarabine; Cytidine; DNA; DNA Methylation; Halogenation; Hydrogen-Ion Concentration; Kinetics; Molecular Dynamics Simulation; Nucleotide Motifs; Telomere

2018
Structural basis for polymerase η-promoted resistance to the anticancer nucleoside analog cytarabine.
    Scientific reports, 2018, 08-23, Volume: 8, Issue:1

    Topics: Antineoplastic Agents; Crystallization; Cytarabine; Cytidine; Deoxycytidine; DNA Repair; DNA Replication; DNA-Directed DNA Polymerase; Humans; Molecular Structure; X-Ray Diffraction

2018
Influence of 2'-Modifications (O-Methylation, Fluorination, and Stereochemical Inversion) on the Base Pairing Energies of Protonated Cytidine Nucleoside Analogue Base Pairs: Implications for the Stabilities of
    Journal of the American Society for Mass Spectrometry, 2023, Jul-05, Volume: 34, Issue:7

    Topics: Base Pairing; Cytarabine; Cytidine; Halogenation; Methylation; Nucleic Acid Conformation

2023