cytarabine has been researched along with cytidine in 83 studies
Timeframe | Studies, this research(%) | All Research% |
---|---|---|
pre-1990 | 44 (53.01) | 18.7374 |
1990's | 15 (18.07) | 18.2507 |
2000's | 15 (18.07) | 29.6817 |
2010's | 7 (8.43) | 24.3611 |
2020's | 2 (2.41) | 2.80 |
Authors | Studies |
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Avery, TL; Chwang, TL; Fridland, A | 1 |
Guinan, M; Huang, N; Miller, GJ; Smith, M | 1 |
Karon, M; Lee, T; Monparler, RL | 1 |
Anderson, JE; Giblett, ER; Teng, YS | 1 |
Alwine, JC; Reed, SI; Stark, GR | 1 |
Mak, TW; Wan, CW | 1 |
Krajewska, E; Shugar, D | 1 |
Laliberté, J; Marquez, VE; Momparler, RL | 1 |
Balzarini, J; De Clercq, E; Neyts, J; Snoeck, R | 1 |
De Clercq, E; Marquez, VE; Murase, J | 1 |
Allegra, CJ; Grem, JL | 1 |
Balázová, E; Novotný, L; Rauko, P; Reichelová, V | 1 |
Mejer, J | 1 |
Allegra, CJ; Chabner, BA; Chu, E; Grem, JL; Johnson, P; Yeh, GC | 1 |
Grem, JL; Harrison, SD; Hawkins, MJ; Plowman, J; Rubinstein, L | 1 |
Novotný, L; Vachálková, A | 1 |
Cory, JG; Matsumoto, M; Rey, DA | 1 |
Broder, S; Mitsuya, H; Webb, TR | 1 |
Datta, G; Gurnani, S; Hosur, RV; Khetrapal, CL; Verma, NC | 1 |
Mejer, J; Mortensen, BT | 1 |
Guschlbauer, W; Hay, J; Jamieson, AT; Mengel, R; Wohlrab, F | 1 |
Arnett, G; Coburn, WC; O'Dell, CA; Riordan, JM; Shannon, WM; Shealy, YF; Thorpe, MC | 1 |
Chou, TC; Fanucchi, MP; Fox, JJ; Watanabe, KA | 1 |
Akerblom, L; Reichard, P | 1 |
Benedict, WF; Karon, M | 1 |
Burchenal, JH; Carter, SK | 1 |
Chabner, BA; Drake, JC; Johns, DG | 1 |
Hosono, H; Kuno, S | 1 |
Hamada, F; Hikita, J; Hirayama, H; Kanai, T; Sugihara, T | 1 |
LePage, GA; Nakai, Y | 1 |
Ganeshaguru, K; Hoffbrand, AV; Tattersall, MH | 1 |
DeYoung, JL; Feller, DR; Notari, RE | 1 |
Loehr, EV; Roberts, D | 1 |
Tattersall, MH | 1 |
Berger, AE; Kuentzel, SL; Neil, GL | 1 |
Cox, RP; Malathi, VG; Meyers, R; Silber, R | 1 |
Hoshi, A; Iigo, M; Kuretani, K; Saneyoshi, M | 1 |
Nagyvary, J; Pollard, DR | 1 |
Remin, M; Shugar, D | 1 |
Hamamura, EK; Moffatt, JG; Prystasz, M; Russell, AF; Verheyden, JP | 1 |
Ichino, M; Kikugawa, K | 1 |
Cass, CE; Paterson, AR | 1 |
Hoshi, A; Kanzawa, F; Kuretani, K | 1 |
Abbott, BJ; Baratta, MC; Greenberg, NH; Kline, I; Venditti, JM | 1 |
Arai, Y; Hoshi, A; Kanazawa, F; Kuretani, K; Saneyoshi, M | 1 |
Brown, RK; Hudson, RA; Lieu, TS; White, BC | 1 |
Burke, PJ; Steuart, CD | 1 |
Brent, TP; Krygier, V; Labitan, A; Momparler, RL | 1 |
Jones, PA; Taylor, SM | 1 |
Evans, WE; Sinkule, JA | 1 |
Beránk, J; Farghali, H; Janků, I; Novotný, L; Ryba, M | 1 |
Cysyk, RL; Hoerauf, RM; Karle, JM | 1 |
Goz, B; Orr, C; Wharton, W | 1 |
Chen, TS | 1 |
Grindey, GB; Kinahan, JJ; Kowal, EP | 1 |
Novotný, L; Pískala, A; Vachálková, A | 1 |
Cubitt, S; Enns, L; Hirani-Hojatti, S; Karimian, K; Mirzayans, R; Murthy, K; Paterson, MC; Radatus, B | 1 |
Bocek, P; Havel, J; Kostálová, A; Krivánková, L; Vargas, G | 1 |
Esche, H; Hoppe, H; Kirch, HC; Schröder, J; Schütte, J; Seeber, S | 1 |
Bachratá, M; Bílková, J; Novotný, L; Rauko, P; Stankovicová, M | 1 |
Hohl, RJ; Jung, KY; Wiemer, AJ; Wiemer, DF | 1 |
Kodama, T; Matsuda, A; Nomura, M; Shuto, S | 1 |
Brinkman, J; Evers, LM; Leen, R; Van Gennip, AH; Van Kuilenburg, AB; Verschuur, AC; Vet, RJ; Voûte, PA | 1 |
Leen, R; van Gennip, AH; van Kuilenburg, AB; Verschuur, AC; Voûte, PA | 1 |
Brinkman, J; Leen, R; Van Gennip, AH; Van Kuilenburg, AB; Verschuur, AC; Voûte, PA | 1 |
Bierau, J; Caron, HN; Helleman, J; Leen, R; Van Gennip, AH; Van Kuilenburg, AB | 1 |
Chen, X; Hohl, RJ; Wiemer, AJ; Wiemer, DF | 1 |
Chen, X; Wiemer, DF | 2 |
Ballmer-Hofer, K; Langer-Machova, Z; Marty, C; Schott, H; Schwendener, RA; Sigrist, S | 1 |
Ailenberg, M; Goldenberg, NM; Silverman, M | 1 |
Cass, CE; Clarke, ML; Damaraju, VL; Lang, T; Mowles, D; Smith, KM; Tackaberry, T; Tomkinson, B; Young, JD; Zhang, J | 1 |
Fujimoto, S; Hotta, A; Koma, M; Nagai, K; Nagasawa, K | 1 |
Endo, Y; Fukushima, M; Ito, M; Murata, D; Natsume, N; Obata, T; Sakamoto, K; Sasaki, T; Yamada, Y; Yamasaki, Y | 1 |
Bernhaus, A; Erker, T; Fritzer-Szekeres, M; Graser, G; Grusch, M; Handler, N; Horvath, Z; Jaeger, W; Jaschke, M; Krupitza, G; Lackner, A; Madlener, S; Ozsvar-Kozma, M; Saiko, P; Szekeres, T | 1 |
Botta, B; Calcaterra, A; D'Acquarica, I; Filippi, A; Fraschetti, C; Piccirillo, S; Rondino, F; Speranza, M | 1 |
Chan, K; Covey, J; Ebrahem, Q; Engelke, KJ; Gu, X; Jankowska, A; Ling, Y; Maciejewski, J; Mahfouz, RZ; Radivoyevitch, T; Saunthararajah, Y; Sekeres, MA; Tabarroki, A; Terse, P; Tiu, R; Visconte, V | 1 |
Terui, Y | 1 |
Beard, BC; Black, ME; Qiu, S; Ruan, H | 1 |
Abrous, DN; André, C; Castellanos-Jankiewicz, A; Clark, S; Cota, D; Guzman-Quevedo, O; Ladeveze, E; Laye, S; Leste-Lasserre, T; Nadjar, A; Rémus-Borel, J; Rey, C | 1 |
Abou Assi, H; Damha, MJ; González, C; Lin, YC; Serrano, I | 1 |
Aggarwal, AK; Buku, A; Choudhury, JR; Prakash, L; Prakash, S; Rechkoblit, O | 1 |
Israel, E; Rodgers, MT; Seidu, YS | 1 |
3 review(s) available for cytarabine and cytidine
Article | Year |
---|---|
Antimetabolites.
Topics: Animals; Antimetabolites; Antineoplastic Agents; Cytarabine; Cytidine; Drug Interactions; Drug Resistance; Floxuridine; Fluorouracil; Folic Acid Antagonists; Humans; Methotrexate; Neoplasms | 1991 |
New cancer chemotherapeutic agents.
Topics: Aldehydes; Amides; Amines; Animals; Antineoplastic Agents; Asparaginase; Azacitidine; Azaguanine; Bleomycin; Carmustine; Chlorides; Cyclization; Cyclohexanes; Cytarabine; Cytidine; Doxorubicin; Glycosides; Humans; Hydroxyurea; Imidazoles; Leukemia, Lymphoid; Leukemia, Myeloid; Mice; Nitrosourea Compounds; Picolinic Acids; Platinum; Podophyllotoxin; Streptozocin; Thiosemicarbazones; Triazenes | 1972 |
The emergence of drug resistance in tumours: a characteristic which may be exploited therapeutically.
Topics: Aminohydrolases; Animals; Cytarabine; Cytidine; DNA; Drug Resistance; Humans; Leukemia; Leukemia L1210; Methotrexate; Neoplasms | 1973 |
80 other study(ies) available for cytarabine and cytidine
Article | Year |
---|---|
2'-O-nitro-1-beta-D-arabinofuranosylcytosine. A new derivative of 1-beta-D-arabinofuranosylcytosine that resists enzymatic deamination and has antileukemic activity.
Topics: Animals; Antimetabolites, Antineoplastic; Cytarabine; Drug Evaluation, Preclinical; Female; Leukemia L1210; Mice; Mice, Inbred Strains | 1983 |
Design, chemical synthesis and antiviral evaluation of 2'-deoxy-2'-fluoro-2'-C-methyl-4'-thionucleosides.
Topics: Antiviral Agents; Dose-Response Relationship, Drug; Drug Design; Hepacivirus; Microbial Sensitivity Tests; Molecular Structure; Structure-Activity Relationship; Thionucleosides; Virus Replication | 2022 |
Cellular phosphorylation of 1-beta-D-arabinofuranosylcytosine 5-azacytidine with intact fibrosarcoma and leukemic cells.
Topics: Animals; Azacitidine; Binding, Competitive; Cells, Cultured; Cricetinae; Cytarabine; Cytidine; Deoxycytidine; Drug Resistance; Fibrosarcoma; Kinetics; Leukemia, Experimental; Mice; Phosphorus; Sarcoma, Experimental | 1975 |
Cytidine deaminase: a new genetic polymorphism demonstrated in human granulocytes.
Topics: Azacitidine; Cytarabine; Cytidine; Cytidine Deaminase; Cytosine; Electrophoresis, Starch Gel; Female; Granulocytes; Humans; Leukocytes; Male; Nucleoside Deaminases; Pedigree; Phenotype; Polymorphism, Genetic | 1975 |
Characterization of the autoregulation of simian virus 40 gene A.
Topics: Azides; Cell Line; Cytarabine; Cytidine; DNA Replication; DNA, Viral; Genes, Viral; Mutation; RNA, Viral; Simian virus 40; Temperature; Transcription, Genetic; Viral Proteins | 1977 |
Deoxycytidine kinase and cytosine nucleoside deaminase activities in synchronized cultures of normal rat kidney cells.
Topics: Cell Cycle; Cell Survival; Cells, Cultured; Cytarabine; Cytidine; Cytosine; Deoxycytidine; Nucleoside Deaminases; Phosphotransferases; Substrate Specificity | 1978 |
Alkylated cytosine nucleosides: substrate and inhibitor properties in enzymatic deamination.
Topics: Alkylation; Chemical Phenomena; Chemistry; Chromatography; Chromatography, Paper; Cytarabine; Cytidine; Cytidine Deaminase; Deoxycytidine; Kinetics; Nucleoside Deaminases; Pyrimidines; Salmonella typhimurium | 1975 |
Potent inhibitors for the deamination of cytosine arabinoside and 5-aza-2'-deoxycytidine by human cytidine deaminase.
Topics: Antineoplastic Agents; Azacitidine; Azepines; Cytarabine; Cytidine; Cytidine Deaminase; Deamination; Decitabine; Humans; Kinetics; Pyrimidine Nucleosides; Tetrahydrouridine | 1992 |
Particular characteristics of the anti-human cytomegalovirus activity of (S)-1-(3-hydroxy-2-phosphonylmethoxypropyl)cytosine (HPMPC) in vitro.
Topics: Animals; Antiviral Agents; Cidofovir; Cytarabine; Cytidine; Cytomegalovirus; Cytosine; Deoxycytidine; DNA, Viral; Ganciclovir; Humans; Organophosphonates; Organophosphorus Compounds; Tumor Cells, Cultured; Virus Replication | 1991 |
Broad-spectrum antiviral and cytocidal activity of cyclopentenylcytosine, a carbocyclic nucleoside targeted at CTP synthetase.
Topics: Adenosine; Amides; Antiviral Agents; Azauridine; Carbon-Nitrogen Ligases; Cell Division; Cytarabine; Cytidine; Deoxycytidine; Drug Synergism; Fluorouracil; HeLa Cells; Humans; Ligases; Nucleosides; Pyrazoles; Ribavirin; Ribonucleosides; Ribose; Thymidine; Tumor Cells, Cultured; Uracil; Virus Replication; Viruses | 1991 |
Sequence-dependent interaction of 5-fluorouracil and arabinosyl-5-azacytosine or 1-beta-D-arabinofuranosylcytosine.
Topics: Antineoplastic Combined Chemotherapy Protocols; Azacitidine; Cell Division; Cell Line; Cell Nucleus; Cell Survival; Colonic Neoplasms; Cytarabine; Cytidine; Deoxycytosine Nucleotides; DNA, Neoplasm; Drug Administration Schedule; Drug Interactions; Fluorouracil; Humans; Nucleic Acids; Thymine Nucleotides; Tumor Stem Cell Assay | 1991 |
Evaluation of synergism of drugs cis-diamminedichloroplatinum (II) and arabinosylcytosine on the level of chemical interaction with DNA and on the growth of mouse leukemia.
Topics: Animals; Cisplatin; Cytarabine; Cytidine; DNA, Neoplasm; Drug Synergism; Female; Fluorescent Dyes; Leukemia L1210; Male; Mice; Mice, Inbred DBA; Spectrophotometry, Ultraviolet | 1991 |
The impact of selected nucleosides on the cytotoxicity of Ara-C in HL60 cells.
Topics: Cell Line; Cell Survival; Cytarabine; Cytidine; Deoxyadenosines; Deoxycytidine; Deoxyguanosine; Drug Interactions; Humans; Kinetics; Leukemia, Promyelocytic, Acute; Nucleosides; Tetrahydrouridine; Uridine | 1991 |
Modulation of cytosine arabinoside toxicity by 3-deazauridine in a murine leukemia model.
Topics: 3-Deazauridine; Animals; Antineoplastic Combined Chemotherapy Protocols; Cytarabine; Cytidine; Drug Resistance; Drug Synergism; Female; Leukemia L1210; Male; Mice; Mice, Inbred Strains; Remission Induction; Survival Rate | 1991 |
Some electrochemical characteristics of synthetic analogs of nucleic acid components. I. Derivatives of cytidine and arabinosylcytosine. An attempt to find correlation among some of their properties.
Topics: Cytarabine; Cytidine; DNA; Oxidation-Reduction; Polarography; Pyrimidine Nucleosides; Solubility | 1990 |
Effects of cytosine arabinoside and hydroxyurea on the synthesis of deoxyribonucleotides and DNA replication in L1210 cells.
Topics: Adenosine; Animals; Cytarabine; Cytidine; Deoxyribonucleotides; DNA Replication; Hydroxyurea; Leukemia L1210; Mice; RNA, Neoplasm; Tumor Cells, Cultured | 1990 |
1-(2,3-Anhydro-beta-D-lyxofuranosyl)cytosine derivatives as potential inhibitors of the human immunodeficiency virus.
Topics: Ancitabine; Chemical Phenomena; Chemistry; Cytarabine; Cytidine; HIV; Magnetic Resonance Spectroscopy; Mass Spectrometry; Thymidine; Uracil; Zidovudine | 1988 |
Mechanism of interaction of the antileukemic drug cytosine arabinoside with aromatic peptides: role of sugar conformation and peptide backbone.
Topics: Amino Acid Sequence; Carbohydrate Conformation; Carbohydrates; Cytarabine; Cytidine; Cytosine; Magnetic Resonance Spectroscopy; Molecular Sequence Data; Peptides; Spectrometry, Fluorescence | 1989 |
Reduction of ara-C cytotoxicity in HL 60 cells by addition of deoxycytidine, cytidine or increased level of cytidine deaminase.
Topics: Bone Marrow; Bone Marrow Cells; Cell Division; Cytarabine; Cytidine; Cytidine Deaminase; Deoxycytidine; Deoxycytidine Kinase; Humans; Leukemia, Promyelocytic, Acute; Nucleoside Deaminases; Phosphotransferases; Tetrahydrouridine; Tretinoin; Tumor Cells, Cultured | 1989 |
The effect of 2'-fluoro-2'-deoxycytidine on herpes virus growth.
Topics: Animals; Cell Division; Cricetinae; Cytarabine; Cytidine; Deoxycytidine; Herpesvirus 1, Equid; Herpesvirus 1, Suid; Humans; Phosphorylation; Simplexvirus; Thymidine Kinase | 1985 |
Carbocyclic analogues of 5-halocytosine nucleosides.
Topics: Bromodeoxycytidine; Chemical Phenomena; Chemistry; Cytarabine; Cytidine; Deoxycytidine; Halogens; Simplexvirus; Virus Replication | 1986 |
Kinetics and substrate specificity of human and canine cytidine deaminase.
Topics: Animals; Arabinofuranosyluracil; Cytarabine; Cytidine; Cytidine Deaminase; Deoxycytidine; Dogs; Humans; Kinetics; Liver; Nucleoside Deaminases; Substrate Specificity | 1986 |
Azidocytidine is a specific inhibitor of deoxyribonucleotide synthesis in 3T6 cells.
Topics: Animals; Cell Division; Cells, Cultured; Cytarabine; Cytidine; Deoxyribonucleotides; DNA Replication; Fibroblasts; Hydroxyurea; Kinetics; Mice; Phosphorylation | 1985 |
Chromatid breakage: differential effect of inhibitors of DNA synthesis during G 2 phase.
Topics: Animals; Azacitidine; Azaguanine; Cell Line; Chromatids; Chromosome Aberrations; Cricetinae; Cytarabine; Cytidine; DNA; DNA Nucleotidyltransferases; Hydroxyurea; Lung; Mitosis; Oxidoreductases; Pyridines; Ribonucleotides; Thiosemicarbazones; Triazines | 1972 |
Deamination of 5-azacytidine by a human leukemia cell cytidine deaminase.
Topics: Aminohydrolases; Azacitidine; Blood Proteins; Carbon Radioisotopes; Chromatography, Ion Exchange; Cytarabine; Cytidine; Deamination; Humans; In Vitro Techniques; Kinetics; Leukemia, Myeloid; Leukocytes; Spectrophotometry, Ultraviolet | 1973 |
The purification and properties of cytidine deaminase from Escherichia coli.
Topics: Aminohydrolases; Chromatography; Cytarabine; Cytidine; Deamination; Deoxycytidine; Deoxyribonucleosides; Edetic Acid; Electrophoresis; Escherichia coli; Hydrogen-Ion Concentration; Metals; Molecular Weight; Pyrimidine Nucleosides; Ribonucleosides; Sulfhydryl Reagents; Urea | 1973 |
Distribution and excretion of cyclocytidine in monkeys, dogs, and rats.
Topics: Anhydrides; Animals; Arabinose; Cytarabine; Cytidine; Dogs; Feces; Half-Life; Haplorhini; Injections, Intravenous; Kidney; Liver; Macaca; Nucleosides; Rats; Uracil | 1974 |
Characterization of the kinase(s) involved in the phosphorylation of - and -2'-deoxythioguanosine.
Topics: Adenosine Triphosphate; Animals; Bone Marrow; Carcinoma, Hepatocellular; Cattle; Cell Line; Cell-Free System; Chromatography, DEAE-Cellulose; Cytarabine; Cytidine; Deoxyribonucleosides; Dithiothreitol; Guanosine; Humans; Isoenzymes; Kinetics; Leukemia L1210; Liver Neoplasms; Lymphoma, Non-Hodgkin; Magnesium; Mercaptopurine; Mice; Mice, Inbred AKR; Mice, Inbred BALB C; Mice, Inbred C3H; Mice, Inbred DBA; Phosphotransferases | 1972 |
The mechanisms of action of three fluorine substituted cytosine analogs: implications for cancer chemotherapy.
Topics: Antineoplastic Agents; Arabinose; Cells, Cultured; Cytarabine; Cytidine; Cytosine; Deoxyuridine; DNA; Flucytosine; Fluorine; Humans; Lymphocytes; Nucleosides; Thymidine; Tritium | 1974 |
Comparative reactivity of cytidine and arabinosylcytosine to their 6-methyl derivatives in the presence of cytidine deaminase.
Topics: Aminohydrolases; Animals; Chemical Phenomena; Chemistry; Cytarabine; Cytidine; Drug Stability; Kidney; Kinetics; Nucleoside Deaminases; Spectrophotometry, Ultraviolet; Structure-Activity Relationship; Swine | 1974 |
Depression of thymidylate synthetase activity in response to cytosine arabinoside.
Topics: Carbon Isotopes; Cell Line; Cytarabine; Cytidine; DNA; Glycine; Humans; Hypoxanthines; In Vitro Techniques; Leukemia, Lymphoid; Leukocytes; Methyltransferases; Nucleic Acids; RNA; Thymidine; Thymine Nucleotides; Time Factors; Tritium; Uracil Nucleotides; Uridine | 1972 |
A microbiological assay for cyclocytidine--disposition studies in mice.
Topics: Animals; Biological Assay; Cytarabine; Cytidine; Deoxycytidine; Enterococcus faecalis; Female; Mice; Nucleosides; Uridine | 1973 |
Studies on nucleoside deaminase. Increase in activity in HeLa cell cultures caused by cytosine arabinoside.
Topics: Alkaline Phosphatase; Aminohydrolases; Antimetabolites; Carbon Isotopes; Cell Fractionation; Culture Media; Cycloheximide; Cytarabine; Cytidine; Deamination; DNA; DNA Nucleotidyltransferases; Glucosephosphate Dehydrogenase; HeLa Cells; L-Lactate Dehydrogenase; Leucine; Methotrexate; Nucleosides; Protein Biosynthesis; Thymidine; Time Factors; Tritium; Uridine | 1973 |
Resistance of cyclocytidine to cytidine deaminase.
Topics: Aminohydrolases; Anhydrides; Animals; Antineoplastic Agents; Cytarabine; Cytidine; Deamination; In Vitro Techniques; Kidney; Mice | 1973 |
Inhibition of pancreatic ribonuclease A by arabinonucleotides.
Topics: Animals; Arabinose; Cattle; Chromatography, Paper; Cytarabine; Cytidine; Cytosine Nucleotides; Kinetics; Nucleosides; Nucleotides; Oligonucleotides; Pancreas; Phosphoric Acids; Photometry; Ribonucleases; Ribose; Spectrophotometry, Ultraviolet; Structure-Activity Relationship; Uracil Nucleotides; Uridine | 1973 |
Conformational analysis of cytidine, 1-beta-D-(arabinofuranosyl)cytosine and their O'-methyl derivatives by proton magnetic resonance spectroscopy.
Topics: Computers; Cytarabine; Cytidine; Magnetic Resonance Spectroscopy; Methods; Methylation; Molecular Conformation; Structure-Activity Relationship | 1973 |
Reactions of 2-acyloxyisobutyryl halides with nucleosides. V. Reactions with cytidine and its derivatives;.
Topics: Anhydrides; Cytarabine; Cytidine; Hydrolysis; Magnetic Resonance Spectroscopy; Temperature | 1974 |
Studies on the Vilsmeier-Haack reaction. IV. Convenient synthesis of 2,2'-anhydro-1- -D-arabinofuranosylcytosine (2,2'-cyclocytidine) and its derivatives.
Topics: Antineoplastic Agents; Chemical Phenomena; Chemistry; Chromatography, Paper; Cyclization; Cytarabine; Cytidine; Methods; Nucleosides | 1972 |
Mediated transport of nucleosides in human erythrocytes. Accelerative exchange diffusion of uridine and thymidine and specificity toward pyrimidine nucleosides as permeants.
Topics: Benzyl Compounds; Biological Transport; Carbon Isotopes; Cytarabine; Cytidine; Deoxyribonucleosides; Diffusion; Erythrocytes; Guanosine; Humans; Kinetics; Nitro Compounds; Ribonucleosides; Structure-Activity Relationship; Sulfides; Thymidine; Uridine | 1972 |
Antitumor activity of cyclocytidine in a variety of tumors.
Topics: Adenocarcinoma; Animals; Antineoplastic Agents; Carcinoma, Ehrlich Tumor; Cell Line; Cyclization; Cyclophosphamide; Cytarabine; Cytidine; Dose-Response Relationship, Drug; Female; Fluorouracil; Leukemia L1210; Leukemia, Experimental; Male; Mercaptopurine; Methotrexate; Mice; Mitomycins; Neoplasms, Experimental; Sarcoma 180 | 1972 |
Studies of the L1210 antileukemic activity of O-2,2'-cyclocytidine, monoacetate (anhydro-ara-C; NSC-129220)--comparison with cytosine arabinoside (NSC-63878) with respect to treatment schedule dependency.
Topics: Acetates; Administration, Oral; Animals; Cyclization; Cytarabine; Cytidine; Drug Resistance; Injections, Intraperitoneal; Injections, Subcutaneous; Leukemia L1210; Male; Mice; Mice, Inbred Strains | 1972 |
2,2'-O-cyclocytidine, an antitumor cytidine analog resistant to cytidine deaminase.
Topics: Aminohydrolases; Animals; Antineoplastic Agents; Chemical Phenomena; Chemistry; Cytarabine; Cytidine; Injections, Intraperitoneal; Leukemia L1210; Mice | 1971 |
Transport of pyrimidine nucleosides across human erythrocyte membranes.
Topics: ABO Blood-Group System; Biological Transport; Carbon Isotopes; Cell Membrane; Cytarabine; Cytidine; Depression, Chemical; Erythrocytes; Humans; Inosine; Kinetics; Purines; Sucrose; Thymidine; Tritium; Uridine | 1971 |
Cytidine deaminase and the development of resistance to arabinosyl cytosine.
Topics: Adult; Aminohydrolases; Bone Marrow; Bone Marrow Cells; Carbon Isotopes; Cyclophosphamide; Cytarabine; Cytidine; Drug Resistance; Humans; Leukemia; Leukemia, Lymphoid; Leukemia, Myeloid, Acute; Spectrum Analysis; Time Factors | 1971 |
Studies on the phosphorylation of cytosine arabinoside in mammalian cells.
Topics: Cells, Cultured; Cytarabine; Cytidine; Cytosine Nucleotides; Deoxyadenosines; Feedback; HeLa Cells; Kinetics; Oxidative Phosphorylation; Phosphotransferases; Tritium | 1971 |
Cellular differentiation, cytidine analogs and DNA methylation.
Topics: Adipose Tissue; Animals; Azacitidine; Cell Differentiation; Cells, Cultured; Cytarabine; Cytidine; Decitabine; Deoxycytidine; DNA; DNA (Cytosine-5-)-Methyltransferases; Methylation; Methyltransferases; Mice; Muscles; Structure-Activity Relationship | 1980 |
High-performance liquid chromatographic assay for cytosine arabinoside, uracil arabinoside and some related nucleosides.
Topics: Arabinofuranosyluracil; Child; Chromatography, High Pressure Liquid; Cytarabine; Cytidine; Deoxycytidine; Humans; Infusions, Parenteral; Kinetics; Leukemia, Myeloid, Acute; Uridine | 1983 |
Kinetics of transport and metabolism of 1-beta-D-arabinofuranosylcytosine and structural analogs by everted perfused rat jejunum.
Topics: Animals; Biological Transport; Biotransformation; Cytarabine; Cytidine; In Vitro Techniques; Intestinal Mucosa; Jejunum; Kinetics; Male; Perfusion; Rats; Rats, Inbred Strains; Structure-Activity Relationship | 1984 |
Labelling of the thymidine and deoxycytidine bases of DNA by [2-14C]deoxycytidine in cultured L1210 cells.
Topics: 3-Deazauridine; Animals; Carbon Radioisotopes; Cytarabine; Cytidine; Deoxycytidine; DNA; Leukemia L1210; Mice; Tetrahydrouridine; Thymidine | 1983 |
Inhibition by deoxycytidine, cytidine, and beta-cytosine arabinoside of the induction of alkaline phosphatase activity in HeLa cells.
Topics: Alkaline Phosphatase; Cytarabine; Cytidine; Deoxycytidine; DNA; Enzyme Induction; HeLa Cells; Hot Temperature; Humans; Idoxuridine; Kinetics | 1980 |
Effects of arabinosyl cytosine and 5-azacytidine on the intestinal absorption of nutrients.
Topics: Amino Acids; Animals; Cytarabine; Cytidine; Deoxycytidine; Electrolytes; Glucose; Intestinal Absorption; Male; Mice; Mice, Inbred Strains | 1982 |
Biochemical and antitumor effects of the combination of thymidine and 1-beta-D-arabinofuranosylcytosine against leukemia L1210.
Topics: Animals; Arabinofuranosylcytosine Triphosphate; Aspartic Acid; Cells, Cultured; Cytarabine; Cytidine; Drug Therapy, Combination; Leukemia L1210; Mice; Phosphonoacetic Acid; Thymidine | 1981 |
Polarographic reduction and carcinogenic index tg alpha of 5-aza nucleosides possessing antileukemic activity.
Topics: Antineoplastic Agents; Azacitidine; Carcinogens; Cytarabine; Cytidine; Molecular Structure; Oxidation-Reduction; Polarography; Structure-Activity Relationship | 1993 |
Comparative genotoxicity of 2,3'-O-cyclocytidine, beta-xylocytidine and 1-beta-D-arabinofuranosylcytosine in human tumor cell lines.
Topics: Ancitabine; Antineoplastic Combined Chemotherapy Protocols; Cell Division; Cell Survival; Child; Cytarabine; Cytidine; DNA Damage; DNA Repair; DNA Replication; DNA, Neoplasm; Drug Screening Assays, Antitumor; Drug Synergism; Humans; Leukemia; Neoplasms; Tumor Cells, Cultured | 1994 |
Separation of aracytidine and cytidine by capillary electrophoretic techniques.
Topics: Boric Acids; Cytarabine; Cytidine; Electrolytes; Electrophoresis, Capillary; Humans; Hydrogen-Ion Concentration; Micelles; Sodium Dodecyl Sulfate | 1996 |
Recombinant gene products of two natural variants of the human cytidine deaminase gene confer different deamination rates of cytarabine in vitro.
Topics: Cytarabine; Cytidine; Cytidine Deaminase; Deamination; DNA, Complementary; Drug Resistance, Neoplasm; Genetic Variation; Humans; Recombinant Proteins; Sequence Analysis, DNA | 1998 |
Transformation kinetics of the 5'-chloro-5'-deoxy analogue of arabinosylcytosine.
Topics: Antineoplastic Agents; Cytarabine; Cytidine; Cytosine; Drug Stability; Hydrogen-Ion Concentration; Kinetics; Structure-Activity Relationship; Thermodynamics | 1999 |
Synthesis of phosphonate derivatives of uridine, cytidine, and cytosine arabinoside.
Topics: Antimetabolites, Antineoplastic; Chemistry, Organic; Cytarabine; Cytidine; Organic Chemistry Phenomena; Organophosphonates; Pyruvate Kinase; Uridine | 2000 |
An efficient method for the preparation of 1'alpha-branched-chain sugar pyrimidine ribonucleosides from uridine: the first conversion of a natural nucleoside into 1'-substituted ribonucleosides.
Topics: Cyclization; Cytarabine; Cytidine; Deoxycytidine; Glycosylation; Molecular Structure; Organoselenium Compounds; Pyrimidine Nucleosides; Ribonucleosides; Selenium; Silicon; Stereoisomerism; Structure-Activity Relationship; Uridine; Vinyl Compounds | 2001 |
Cyclopentenyl cytosine induces apoptosis and increases cytarabine-induced apoptosis in a T-lymphoblastic leukemic cell-line.
Topics: Annexin A5; Antimetabolites, Antineoplastic; Antineoplastic Agents; Apoptosis; Cell Division; Cytarabine; Cytidine; Dose-Response Relationship, Drug; Drug Synergism; Humans; Leukemia, T-Cell; Necrosis; Tumor Cells, Cultured | 2001 |
Cyclopentenyl cytosine increases the phosphorylation and incorporation into dna of arabinofu-ranosyl cytosine in a myeloid leukemic cell-line.
Topics: Antimetabolites, Antineoplastic; Antineoplastic Agents; Carbon-Nitrogen Ligases; Cytarabine; Cytidine; Cytidine Diphosphate; Cytidine Monophosphate; Deoxycytosine Nucleotides; DNA; Dose-Response Relationship, Drug; Enzyme Inhibitors; HL-60 Cells; Humans; Leukemia, Myeloid; Phosphorylation | 2000 |
Cyclopentenyl cytosine increases the phosphorylation and incorporation into DNA of 1-beta-D-arabinofuranosyl cytosine in a human T-lymphoblastic cell line.
Topics: Antineoplastic Agents; Apoptosis; Cell Division; Cytarabine; Cytidine; Cytidine Triphosphate; Deoxycytosine Nucleotides; DNA; Dose-Response Relationship, Drug; Drug Resistance, Neoplasm; Humans; Phosphorylation; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Time Factors; Tumor Cells, Cultured | 2002 |
Cyclopentenyl cytosine primes SK-N-BE(2)c neuroblastoma cells for cytarabine toxicity.
Topics: Antimetabolites, Antineoplastic; Apoptosis; Carbon-Nitrogen Ligases; Cell Cycle; Cell Division; Cytarabine; Cytidine; DNA, Neoplasm; Dose-Response Relationship, Drug; Drug Resistance, Neoplasm; Drug Synergism; Enzyme Inhibitors; Humans; Neuroblastoma; Phosphorylation; Tumor Cells, Cultured | 2003 |
Stereoselective synthesis of the 5'-hydroxy-5'-phosphonate derivatives of cytidine and cytosine arabinoside.
Topics: Cytarabine; Cytidine; Drug Screening Assays, Antitumor; Humans; Hydrolysis; K562 Cells; Magnetic Resonance Spectroscopy; Molecular Structure; Organophosphonates; Stereoisomerism; Structure-Activity Relationship; Tumor Cells, Cultured | 2002 |
Synthesis of 5'-amino-5'-phosphonate analogues of pyrimidine nucleoside monophosphates.
Topics: Chromatography, Thin Layer; Cytarabine; Cytidine; Indicators and Reagents; Magnetic Resonance Spectroscopy; Organophosphonates; Oxidation-Reduction; Pyrimidine Nucleosides; Stereoisomerism; Uridine | 2003 |
Alpha-phosphono lactone analogues of cytidine and cytosine arabinoside diphosphates: synthesis via ring closing metathesis.
Topics: Arabinose; Cytarabine; Cytidine; Cytidine Diphosphate; Cytosine; Indicators and Reagents; Lactones; Models, Molecular; Organophosphonates; Stereoisomerism | 2003 |
Isolation and characterization of a scFv antibody specific for tumor endothelial marker 1 (TEM1), a new reagent for targeted tumor therapy.
Topics: Antibody Specificity; Antigens, CD; Antigens, Neoplasm; Cell Line; Cytarabine; Cytidine; Humans; Immunoglobulin Fragments; Liposomes; Membrane Proteins; Neoplasm Proteins; Neoplasms; Peptide Library; Recombinant Proteins | 2006 |
Description of a PCR-based technique for DNA splicing and mutagenesis by producing 5' overhangs with run through stop DNA synthesis utilizing Ara-C.
Topics: Alternative Splicing; Base Composition; Cloning, Molecular; Codon, Terminator; Cofilin 1; Cytarabine; Cytidine; DNA; DNA Mutational Analysis; DNA Primers; DNA Restriction Enzymes; DNA, Recombinant; Gene Deletion; Humans; Mutagenesis; Mutagenesis, Site-Directed; Nucleic Acid Conformation; Polymerase Chain Reaction; Sequence Analysis, DNA | 2005 |
The role of human nucleoside transporters in cellular uptake of 4'-thio-beta-D-arabinofuranosylcytosine and beta-D-arabinosylcytosine.
Topics: Animals; Arabinonucleosides; Biological Transport; Cell Line, Tumor; Cell Survival; Cytarabine; Cytidine; Dose-Response Relationship, Drug; Equilibrative-Nucleoside Transporter 2; Female; HeLa Cells; Humans; Membrane Potentials; Nucleoside Transport Proteins; Oocytes; Saccharomyces cerevisiae; Thioinosine; Transfection; Tritium; Uridine; Xenopus laevis | 2006 |
Cytidine is a novel substrate for wild-type concentrative nucleoside transporter 2.
Topics: Amino Acid Substitution; Animals; Antimetabolites, Antineoplastic; Biological Transport; Chlorocebus aethiops; COS Cells; Cytarabine; Cytidine; Deoxycytidine; Dose-Response Relationship, Drug; Gemcitabine; Genotype; Kinetics; Male; Membrane Transport Proteins; Mice; Thymidine; Transfection; Tritium; Uridine | 2006 |
Cellular localization and functional characterization of the equilibrative nucleoside transporters of antitumor nucleosides.
Topics: Antimetabolites, Antineoplastic; Biological Transport; Cell Membrane; Cell Proliferation; Cytarabine; Cytidine; Equilibrative Nucleoside Transport Proteins; Equilibrative Nucleoside Transporter 1; Equilibrative-Nucleoside Transporter 2; Fibrosarcoma; Green Fluorescent Proteins; Humans; Nucleoside Transport Proteins; RNA, Messenger; Stomach Neoplasms; Tumor Cells, Cultured | 2007 |
N-hydroxy-N'-(3,4,5-trimethoxyphenyl)-3,4,5-trimethoxy-benzamidine, a novel resveratrol analog, inhibits ribonucleotide reductase in HL-60 human promyelocytic leukemia cells: synergistic antitumor activity with arabinofuranosylcytosine.
Topics: Antineoplastic Agents; Apoptosis; Cell Cycle; Cytarabine; Cytidine; Drug Synergism; Enzyme Inhibitors; HL-60 Cells; Humans; Resveratrol; Ribonucleotide Reductases; Stilbenes | 2007 |
Chirality effects on the IRMPD spectra of basket resorcinarene/nucleoside complexes.
Topics: Cytarabine; Cytidine; Cytosine; Molecular Structure; Nucleosides; Protons; Spectrophotometry, Infrared; Stereoisomerism | 2012 |
Increased CDA expression/activity in males contributes to decreased cytidine analog half-life and likely contributes to worse outcomes with 5-azacytidine or decitabine therapy.
Topics: Animals; Azacitidine; Cytarabine; Cytidine; Cytidine Deaminase; Decitabine; DNA (Cytosine-5-)-Methyltransferase 1; DNA (Cytosine-5-)-Methyltransferases; Female; Gene Expression Regulation, Neoplastic; Humans; Leukemia, Myeloid, Acute; Male; Mice; Myelodysplastic Syndromes; Polymorphism, Single Nucleotide; Survival Analysis; Treatment Outcome | 2013 |
[Cytidine].
Topics: Antineoplastic Agents; Arabinonucleosides; Cytarabine; Cytidine; Deoxycytidine; Gemcitabine; Humans; Neoplasms | 2015 |
Creation of zebularine-resistant human cytidine deaminase mutants to enhance the chemoprotection of hematopoietic stem cells.
Topics: Amino Acid Sequence; Cytarabine; Cytidine; Cytidine Deaminase; Drug Resistance; Escherichia coli; Hematopoietic Stem Cell Transplantation; Humans; Mutagenesis; Mutation; Protein Engineering | 2016 |
Inhibiting Microglia Expansion Prevents Diet-Induced Hypothalamic and Peripheral Inflammation.
Topics: Adiposity; Animals; Antimitotic Agents; Arabinonucleosides; Arcuate Nucleus of Hypothalamus; Body Weight; Cell Proliferation; Cytarabine; Cytidine; Diet, High-Fat; Eating; Hypothalamus; Inflammation; Interleukin-1beta; Leptin; Macrophages, Peritoneal; Male; Mice; Microglia; NF-kappa B; Obesity; Tumor Necrosis Factor-alpha; Weight Gain | 2017 |
Probing Synergistic Effects of DNA Methylation and 2'-β-Fluorination on i-Motif Stability.
Topics: Cytarabine; Cytidine; DNA; DNA Methylation; Halogenation; Hydrogen-Ion Concentration; Kinetics; Molecular Dynamics Simulation; Nucleotide Motifs; Telomere | 2018 |
Structural basis for polymerase η-promoted resistance to the anticancer nucleoside analog cytarabine.
Topics: Antineoplastic Agents; Crystallization; Cytarabine; Cytidine; Deoxycytidine; DNA Repair; DNA Replication; DNA-Directed DNA Polymerase; Humans; Molecular Structure; X-Ray Diffraction | 2018 |
Influence of 2'-Modifications (O-Methylation, Fluorination, and Stereochemical Inversion) on the Base Pairing Energies of Protonated Cytidine Nucleoside Analogue Base Pairs: Implications for the Stabilities of
Topics: Base Pairing; Cytarabine; Cytidine; Halogenation; Methylation; Nucleic Acid Conformation | 2023 |