cytarabine and cytidine monophosphate

cytarabine has been researched along with cytidine monophosphate in 28 studies

Research

Studies (28)

TimeframeStudies, this research(%)All Research%
pre-199010 (35.71)18.7374
1990's16 (57.14)18.2507
2000's2 (7.14)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Capasso, JM; Hirschberg, CB2
Dorr, RT; Iyengar, BS; Remers, WA1
Buchheit, DJ; Hong, CI; Kirisits, AJ; Nechaev, A; West, CR2
Kim, SH; Rosowsky, A; Ross, J; Wick, MM1
Abraham, TW; Kalman, TI; McIntee, EJ; Wagner, CR1
Zaborowska, D; Zuk, J1
Deguchi, K; Kageyama, S; Komada, F; Minami, N; Morita, K; Nishikawa, M; Shirakawa, S; Uemura, Y1
Higashigawa, M; Hori, H; Kawasaki, H; Ohkubo, T; Sakurai, M; Yoshizumi, T1
Chen, SR; Cuddy, DP; Ross, DD1
Suga, T; Takayama, H; Watanabe, T; Yamada, J; Yoshida, Y1
Arakawa, M; Ekimoto, H; Ishii, T; Kusama, K; Nagahata, T; Shibasaki, C; Takahashi, K; Uchida, T1
Kodama, K; Kuninaka, A; Morozumi, M; Saitoh, K; Saneyoshi, M; Yoshino, H1
Haynes, RH; Kunz, BA; McIntosh, EM1
Rooze, M1
Campbell, J; Mayhew, E; Rustum, YM; Szoka, F1
Myers-Robfogel, MW; Spataro, AC1
Harrington, C; Perrino, FW1
Arie, Y; Hirai, M; Kikukawa, M; Kodo, H; Kumakawa, T; Mizutani, R; Mori, M; Murai, Y; Nakamura, N; Tsutsumi, H1
Braess, J; Hiddemann, W; Kaufmann, C; Ramsauer, B; Schleyer, E; Schüssler, M; Unterhalt, M; Wilde, S1
Niitsu, N; Shikoshi, K; Takada, M; Umeda, M1
Tsukagoshi, S1
Ito, T; Konishi, H; Maesako, Y; Mori, S; Ueda, Y; Yagiri, Y1
Braess, J; Freund, M; Hanauske, A; Heil, G; Hiddemann, W; Kaufmann, C; Kern, W; Schleyer, E; Schüssler, M1
Harvey, S; Mazur, DJ; Perrino, FW; Ward, H1
Berger, U; Hehlmann, R; Hochhaus, A; Kuhn, C; Reiter, A1
Leen, R; van Gennip, AH; van Kuilenburg, AB; Verschuur, AC; Voûte, PA1

Reviews

2 review(s) available for cytarabine and cytidine monophosphate

ArticleYear
[Recent development of antitumor antimetabolites in Japan--cytosine arabinoside analogues].
    Gan to kagaku ryoho. Cancer & chemotherapy, 1997, Volume: 24, Issue:7

    Topics: Animals; Antimetabolites, Antineoplastic; Arabinonucleotides; Carcinoma, Non-Small-Cell Lung; Clinical Trials, Phase I as Topic; Clinical Trials, Phase II as Topic; Cytarabine; Cytidine Monophosphate; Deoxycytidine; Gemcitabine; Humans; Lung Neoplasms; Mice; Neoplasm Transplantation

1997
AraC-based pharmacotherapy of chronic myeloid leukaemia.
    Expert opinion on pharmacotherapy, 2001, Volume: 2, Issue:7

    Topics: Aged; Antimetabolites, Antineoplastic; Antineoplastic Combined Chemotherapy Protocols; Arabinonucleotides; Clinical Trials as Topic; Cytarabine; Cytidine Monophosphate; Drug Administration Schedule; Guidelines as Topic; Humans; Interferons; Leukemia, Myelogenous, Chronic, BCR-ABL Positive; Survival Analysis

2001

Trials

3 trial(s) available for cytarabine and cytidine monophosphate

ArticleYear
Pharmacokinetics of Ara-CMP-Stearate (YNK01): phase I study of the oral Ara-C derivative.
    Leukemia, 1995, Volume: 9, Issue:6

    Topics: Administration, Oral; Antineoplastic Agents; Arabinofuranosyluracil; Arabinonucleotides; Cytarabine; Cytidine Monophosphate; Dose-Response Relationship, Drug; Half-Life; Humans; Leukemia, Myeloid, Acute; Lymphoma, Non-Hodgkin; Statistics, Nonparametric

1995
[A pharmacokinetic study of the value of oral cytarabine ocfosfate in the treatment of hematological malignancies].
    [Rinsho ketsueki] The Japanese journal of clinical hematology, 1998, Volume: 39, Issue:5

    Topics: Administration, Oral; Aged; Antineoplastic Agents; Arabinonucleotides; Cytarabine; Cytidine Monophosphate; Female; Humans; Leukemia, Myeloid, Acute; Male; Middle Aged; Myelodysplastic Syndromes; Time Factors

1998
Oral cytarabine ocfosfate in acute myeloid leukemia and non-Hodgkin's lymphoma--phase I/II studies and pharmacokinetics.
    Leukemia, 1998, Volume: 12, Issue:10

    Topics: Acute Disease; Administration, Oral; Adult; Antineoplastic Agents; Arabinonucleotides; Biological Availability; Cytarabine; Cytidine Monophosphate; Diarrhea; Dose-Response Relationship, Drug; Half-Life; Humans; Infusions, Intravenous; Leukemia, Myeloid; Lymphoma, Non-Hodgkin; Metabolic Clearance Rate; Prodrugs; Regression Analysis

1998

Other Studies

23 other study(ies) available for cytarabine and cytidine monophosphate

ArticleYear
Mechanisms of glycosylation and sulfation in the Golgi apparatus: evidence for nucleotide sugar/nucleoside monophosphate and nucleotide sulfate/nucleoside monophosphate antiports in the Golgi apparatus membrane.
    Proceedings of the National Academy of Sciences of the United States of America, 1984, Volume: 81, Issue:22

    Topics: Adenine Nucleotides; Adenosine Monophosphate; Animals; Biological Transport; Cytidine Monophosphate; Cytidine Monophosphate N-Acetylneuraminic Acid; Golgi Apparatus; Guanosine Diphosphate Fucose; Guanosine Monophosphate; Nucleoside Diphosphate Sugars; Phosphoadenosine Phosphosulfate; Rats; Sialic Acids

1984
Effect of nucleotides on translocation of sugar nucleotides and adenosine 3'-phosphate 5'-phosphosulfate into Golgi apparatus vesicles.
    Biochimica et biophysica acta, 1984, Oct-17, Volume: 777, Issue:1

    Topics: Adenine Nucleotides; Animals; Binding, Competitive; Biological Transport; Cytidine Monophosphate; Cytidine Monophosphate N-Acetylneuraminic Acid; Golgi Apparatus; Guanine Nucleotides; Guanosine Diphosphate Fucose; Liver; Nucleoside Diphosphate Sugars; Nucleotides; Phosphoadenosine Phosphosulfate; Rats; Sialic Acids; Structure-Activity Relationship; Uridine Monophosphate

1984
Additional nucleotide derivatives of mitosenes. Synthesis and activity against parental and multidrug resistant L1210 leukemia.
    Journal of medicinal chemistry, 1991, Volume: 34, Issue:7

    Topics: Animals; Antineoplastic Agents; Cell Line; Chemical Phenomena; Chemistry; Leukemia L1210; Mice; Mitomycin; Mitomycins; Nucleotides

1991
Nucleoside conjugates. 6. Synthesis and comparison of antitumor activity of 1-beta-D-arabinofuranosylcytosine conjugates of corticosteroids and selected lipophilic alcohols.
    Journal of medicinal chemistry, 1985, Volume: 28, Issue:2

    Topics: Adrenal Cortex Hormones; Animals; Antineoplastic Agents; Arabinonucleotides; Cytidine Deaminase; Esters; Female; Humans; Leukemia L1210; Male; Mice

1985
Lipophilic 5'-(alkyl phosphate) esters of 1-beta-D-arabinofuranosylcytosine and its N4-acyl and 2,2'-anhydro-3'-O-acyl derivatives as potential prodrugs.
    Journal of medicinal chemistry, 1982, Volume: 25, Issue:2

    Topics: Animals; Antineoplastic Agents; Chemical Phenomena; Chemistry; Cytarabine; Drug Resistance; Esters; Hydrolysis; Leukemia L1210; Melanoma; Mice; Neoplasms, Experimental

1982
Synthesis and biological activity of aromatic amino acid phosphoramidates of 5-fluoro-2'-deoxyuridine and 1-beta-arabinofuranosylcytosine: evidence of phosphoramidase activity.
    Journal of medicinal chemistry, 1996, Nov-08, Volume: 39, Issue:23

    Topics: Animals; Cell Division; Cell Line; Cytarabine; Floxuridine; Humans; Magnetic Resonance Spectroscopy; Mice; Organophosphorus Compounds; Phosphoric Monoester Hydrolases; Thymidylate Synthase; Tumor Cells, Cultured

1996
The effect of DNA replication on mutation of the Saccharomyces cerevisiae CDC8 gene.
    Current genetics, 1990, Volume: 17, Issue:4

    Topics: Arabinonucleotides; Buffers; Caffeine; Cycloheximide; Cytarabine; Cytidine Monophosphate; DNA Replication; DNA, Fungal; Genes, Fungal; Hydroxyurea; Mutation; Phenotype; Phosphates; Saccharomyces cerevisiae; Ultraviolet Rays

1990
[A case of complete remission from acute unclassified leukemia achieved by using a prodrug of ara C, stearyl-ara-CMP (YNK01)].
    Gan no rinsho. Japan journal of cancer clinics, 1990, Volume: 36, Issue:12

    Topics: Acute Disease; Administration, Oral; Antineoplastic Agents; Arabinonucleotides; Cytarabine; Cytidine Monophosphate; Drug Administration Schedule; Female; Humans; Leukemia; Middle Aged; Prodrugs; Remission Induction

1990
Deoxyribonucleoside triphosphate pools and Ara-CTP levels in P388 murine leukemic cells treated with 1-B-D-arabinofuranosylcytosine-5'-stearylphosphate which is a newly synthesized derivative of 1-B-D-arabinofuranosylcytosine.
    Medical oncology and tumor pharmacotherapy, 1990, Volume: 7, Issue:4

    Topics: Administration, Oral; Animals; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Arabinofuranosylcytosine Triphosphate; Arabinonucleotides; Chromatography, High Pressure Liquid; Cytarabine; Cytidine Monophosphate; Deoxyribonucleotides; Leukemia P388; Male; Mice

1990
Effects of 1-beta-D-arabinofuranosylcytosine on DNA replication intermediates monitored by pH-step alkaline elution.
    Cancer research, 1990, May-01, Volume: 50, Issue:9

    Topics: Arabinonucleotides; Cytarabine; Cytidine Monophosphate; DNA Replication; DNA, Neoplasm; Humans; Hydrogen-Ion Concentration; Kinetics; Leukemia, Promyelocytic, Acute; Thymidine; Tumor Cells, Cultured

1990
Participation of the peroxisomal beta-oxidation system in the chain-shortening of PCA16, a metabolite of the cytosine arabinoside prodrug, YNKO1, in rat liver.
    Biochemical pharmacology, 1990, May-15, Volume: 39, Issue:10

    Topics: Animals; Arabinonucleotides; Cells, Cultured; Clofibrate; Coenzyme A Ligases; Cytarabine; Cytidine Monophosphate; Cytosine Nucleotides; Hydrogen Peroxide; Ketone Bodies; Liver; Microbodies; Mitochondria, Liver; Palmitates; Prodrugs; Rats; Rats, Inbred Strains; Repressor Proteins; Saccharomyces cerevisiae Proteins

1990
[Antitumor activity of a novel analog of cytarabine, 4-amino-1-beta-D-arabinofuranosyl-2(1H)-pyrimidinone 5'-(sodium octadecyl phosphate) monohydrate (YNK01)].
    Gan to kagaku ryoho. Cancer & chemotherapy, 1990, Volume: 17, Issue:8 Pt 1

    Topics: Administration, Oral; Animals; Antineoplastic Agents; Arabinonucleotides; Cytarabine; Cytidine Monophosphate; Cytosine Nucleotides; Drug Administration Schedule; Drug Screening Assays, Antitumor; Female; Injections, Intraperitoneal; Injections, Intravenous; Leukemia L1210; Male; Mice; Neoplasms, Experimental; Tumor Cells, Cultured

1990
Antitumor activity and pharmacology of 1-beta-D-arabinofuranosylcytosine-5'-stearylphosphate: an orally active derivative of 1-beta-D-arabinofuranosylcytosine.
    Japanese journal of cancer research : Gann, 1989, Volume: 80, Issue:7

    Topics: Administration, Oral; Animals; Antineoplastic Agents; Arabinonucleotides; Cytarabine; Cytidine Monophosphate; Cytosine Nucleotides; Drug Administration Schedule; Leukemia L1210; Metabolic Clearance Rate; Mice; Solubility; Structure-Activity Relationship

1989
Inhibition of DNA replication in Saccharomyces cerevisiae by araCMP.
    Current genetics, 1986, Volume: 10, Issue:8

    Topics: Arabinonucleotides; Biological Transport; Cell Division; Chromatography, High Pressure Liquid; Cytarabine; Cytidine Monophosphate; Cytosine Nucleotides; DNA Replication; DNA, Fungal; Mitosis; Recombination, Genetic; Saccharomyces cerevisiae; Thymine Nucleotides

1986
1-beta-D-arabinofuranosylcytosine conjugates of thioether phospholipids as a new class of potential antitumor drugs.
    Cancer drug delivery, 1986,Spring, Volume: 3, Issue:2

    Topics: Animals; Antineoplastic Agents; Arabinonucleotides; Cytarabine; Cytidine Monophosphate; Leukemia L1210; Leukemia P388; Leukemia, Experimental; Male; Mice; Mice, Inbred DBA; Structure-Activity Relationship

1986
Correlations between necrotic patterns and limb skeletal defects induced by antimitotic drugs in the mouse.
    Progress in clinical and biological research, 1983, Volume: 110 Pt A

    Topics: Abnormalities, Drug-Induced; Animals; Antibiotics, Antineoplastic; Cell Survival; Cytarabine; Cytidine Monophosphate; Ectoderm; Extremities; Female; Glycine; Hyperplasia; Limb Deformities, Congenital; Mesoderm; Mice; Mitosis; Necrosis; Pregnancy; Time Factors

1983
Inability of liposome encapsulated 1-beta-D-arabinofuranosylcytosine nucleotides to overcome drug resistance in L1210 cells.
    European journal of cancer & clinical oncology, 1981, Volume: 17, Issue:7

    Topics: Animals; Arabinofuranosylcytosine Triphosphate; Arabinonucleotides; Cells, Cultured; Cytarabine; Cytidine Monophosphate; DNA, Neoplasm; Drug Resistance; Female; Leukemia L1210; Liposomes; Mice; Mice, Inbred DBA

1981
1-beta-D-arabinofuranosylcytosine nucleotide inhibition of sialic acid metabolism in WI-38 cells.
    Cancer research, 1980, Volume: 40, Issue:6

    Topics: Arabinofuranosylcytosine Triphosphate; Arabinonucleotides; Cell Line; Cells, Cultured; Cytarabine; Cytidine Monophosphate; Cytosine Nucleotides; Humans; Sialic Acids; Sialyltransferases; Transferases

1980
The effects of cytosine arabinoside on RNA-primed DNA synthesis by DNA polymerase alpha-primase.
    The Journal of biological chemistry, 1995, Nov-03, Volume: 270, Issue:44

    Topics: Arabinonucleotides; Base Sequence; Cytarabine; Cytidine Monophosphate; DNA Primase; DNA Primers; DNA Replication; Kinetics; Molecular Sequence Data; RNA Nucleotidyltransferases; Templates, Genetic

1995
[Plasma concentration of cytosine arabinoside (Ara-C) in the elderly patients with hematological malignancy treated by Ara-C or cytarabine ocfosfate (SPAC)].
    Nihon Ronen Igakkai zasshi. Japanese journal of geriatrics, 1995, Volume: 32, Issue:3

    Topics: Administration, Oral; Aged; Aged, 80 and over; Antineoplastic Agents; Arabinonucleotides; Cytarabine; Cytidine Monophosphate; Female; Humans; Infusions, Intravenous; Injections, Subcutaneous; Leukemia, Myeloid, Acute; Male; Myelodysplastic Syndromes

1995
[Therapy-related acute non-lymphocytic leukemia (M2) with 7;11 chromosome translocation induced into complete remission by low dose cytosine arabinoside and cytarabine ocfosfate therapy].
    Nihon Ronen Igakkai zasshi. Japanese journal of geriatrics, 1994, Volume: 31, Issue:6

    Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Arabinonucleotides; Chromosomes, Human, Pair 11; Chromosomes, Human, Pair 7; Cytarabine; Cytidine Monophosphate; Female; Humans; Leukemia, Myeloid, Acute; Neoplasms, Second Primary; Remission Induction; Translocation, Genetic

1994
Exonucleases and the incorporation of aranucleotides into DNA.
    Cell biochemistry and biophysics, 1999, Volume: 30, Issue:3

    Topics: Animals; Cattle; Chromatography; Cytarabine; Cytidine Monophosphate; DNA; DNA Polymerase gamma; DNA Repair; DNA Replication; DNA-Directed DNA Polymerase; Electrophoresis, Polyacrylamide Gel; Exodeoxyribonucleases; HL-60 Cells; Humans; Kinetics; Leukemia; Recombinant Proteins; Thymus Gland; Time Factors; Tissue Inhibitor of Metalloproteinases

1999
Cyclopentenyl cytosine increases the phosphorylation and incorporation into dna of arabinofu-ranosyl cytosine in a myeloid leukemic cell-line.
    Advances in experimental medicine and biology, 2000, Volume: 486

    Topics: Antimetabolites, Antineoplastic; Antineoplastic Agents; Carbon-Nitrogen Ligases; Cytarabine; Cytidine; Cytidine Diphosphate; Cytidine Monophosphate; Deoxycytosine Nucleotides; DNA; Dose-Response Relationship, Drug; Enzyme Inhibitors; HL-60 Cells; Humans; Leukemia, Myeloid; Phosphorylation

2000