cytarabine and camptothecin

cytarabine has been researched along with camptothecin in 47 studies

Research

Studies (47)

Timeframe	Studies, this research(%)	All Research%
pre-1990	13 (27.66)	18.7374
1990's	12 (25.53)	18.2507
2000's	14 (29.79)	29.6817
2010's	8 (17.02)	24.3611
2020's	0 (0.00)	2.80

Authors

Authors	Studies
Corbett, TH; Edelstein, M; Hazeldine, ST; Horwitz, JP; Kushner, J; Palomino, E; Paluch, J; Polin, L; White, K	1
Addo, SN; Das, SG; Doshi, JM; Hermanson, DL; Srinivasan, B; Tian, D; Xing, C	1
Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A	1
Afshari, CA; Chen, Y; Dunn, RT; Hamadeh, HK; Kalanzi, J; Kalyanaraman, N; Morgan, RE; van Staden, CJ	1
Asher, Y; Becker, Y	1
Kelly, DC; Lescott, T	1
Boyse, EA; Goldstein, G; Hammerling, U; Storrie, B	1
Bergevin, PR; Blom, J; Tormey, DC	1
Tobey, RA	1
Crissman, HA; Tobey, RA	1
Gang, M; Kline, I; Sirica, AE; Venditti, JM; Woodman, RJ	1
Kline, I	1
Brockman, RW	1
Bhuyan, BK; Fraser, TJ	1
Becker, Y; Ben-Zeev, A; Weinberg, E	1
Homan, ER; Neil, GL	1
Bhuyan, BK; Fraser, TJ; Gray, LG; Kuentzel, SL; Neil, GL	1
Kataoka, S; Kawai, H; Mashima, T; Naito, M; Tsuruo, T	1
Tsukagoshi, S	1
Emoto, Y; Kharbanda, S; Kisaki, H; Kufe, D; Manome, Y	1
Darzynkiewicz, Z; Feldman, E; Halicka, HD; Seiter, K; Traganos, F	1
Ahmed, T; Darzynkiewicz, Z; Feldman, EJ; Halicka, HD; Lake, D; Seiter, K; Traganos, F	1
Mashima, T; Tsuruo, T	1
Akiyama, Y; Furusho, K; Kataoka, A; Koishi, S; Kubota, M; Lin, YW; Sawada, M; Usami, I; Watanabe, Ki	1
Akiyama, Y; Furusho, K; Kataoka, A; Kitoh, T; Koishi, S; Kubota, M; Lin, YW; Sawada, M; Usami, I; Watanabe, K	1
Geller, HM; Greene, LA; Morris, EJ; Padmanabhan, J; Park, DS; Shelanski, ML	1
Bhalla, K; Bullock, G; Huang, Y; Maria Ibrado, A; Miyashita, T; Ray, S; Reed, J	1
Hunter, N; Meyn, RE; Mirkovic, N; Story, MD	1
Ishiura, S; Koriyama, H; Kouchi, Z; Momoi, T; Saido, TC; Suzuki, K; Umeda, T	1
Gioffre, C; Kohlhagen, G; Pommier, Y; Pourquier, P; Takebayashi, Y; Urasaki, Y	1
Bieszczad, CK; Cleaveland, ES; Craig, RW; Ma, Y; Mohandas, TK; Park, JP; Vrana, JA	1
Funato, T; Imoto, I; Inazawa, J; Mihara, S; Naito, S; Okamoto, H; Saito-Ohara, F; Tomida, A; Tsuruo, T; Yasui, K; Yokomizo, A; Zhao, C	1
Arlander, SJ; Hackbarth, J; Hopkins, KM; Karnitz, LM; Kaufmann, SH; Lieberman, HB; Loegering, D; Roos-Mattjus, P; Vroman, BT	1
Bjornsti, MA; Bohlander, M; Brouwer, J; de Jong, LA; Schellens, JH; van Delft, F; van Eijndhoven, MA; van Waardenburg, RC	1
Abdel-Aziz, W; Hickey, RJ; Malkas, LH	1
Bjornsti, MA; de Jong, LA; Jansen, LE; Pluim, D; Schellens, JH; van Eijndhoven, MA; van Waardenburg, RC; Verseyden, C	1
Baer, MR; Ford, LA; Greco, WR; Minderman, H; O'Loughlin, KL; Pendyala, L; Smith, PF; Sweeney, KG; Wetzler, M	1
Beyer, U; Gnad-Vogt, SU; Hochhaus, A; Hofheinz, RD	1
Akutsu, M; Furukawa, Y; Izumi, T; Kano, Y; Kobayashi, H; Mano, H; Tsunoda, S	1
Bally, MB; Harasym, NL; Harasym, TO; Janoff, AS; Johnstone, SA; Mayer, LD; Ramsay, EC; Shew, CR; Tardi, PG	1
Adams, DJ; Giles, F; Jacobsen, TF; Myhren, F; Rizzieri, DA; Sandvold, ML	1
Bonnabry, P; Fleury-Souverain, S; Geiser, L; Hochstrasser, D; Nussbaumer, S; Sadeghipour, F; Veuthey, JL	1
Chung, I; Eastman, A; Garner, KM; Montano, R; Parry, D	1
Allorge, D; Barthelemy, C; Bonnabry, P; Décaudin, B; Humbert, L; Lebecque, M; Odou, P; Pinturaud, M; Richeval, C; Sidikou, O; Simon, N; Soichot, M; Vasseur, M	1
Al Abo, M; Huang, SY; Kiselev, E; Liu, X; Plunkett, W; Pommier, Y; Rajapakse, VN; Sasanuma, H; Takeda, S	1
He, W; Hu, X; Jiang, W; Li, Z; Liu, R; Luan, Y; Zhang, D; Zhang, J	1
Fukuda, M; Hosokawa, M; Iwakawa, S; Masuda, A; Tanaka, S; Ueda, K	1

Reviews

4 review(s) available for cytarabine and camptothecin

Article	Year
Guide to the use of cancer chemotherapeutic agents. Modern treatment, 1972, Volume: 9, Issue:2 Topics: Alkylating Agents; Allopurinol; Antibiotics, Antineoplastic; Antimetabolites; Antineoplastic Agents; Asparaginase; Azaserine; Azauridine; Bleomycin; Camptothecin; Carmustine; Cell Division; Cyclophosphamide; Cytarabine; Dactinomycin; Daunorubicin; Doxorubicin; Fluorouracil; Humans; Kinetics; Neoplasms; Nitrogen Mustard Compounds; Procarbazine; Triazines; Vincristine	1972
Biochemical aspects of drug combinations. Cancer chemotherapy reports. Part 2, 1974, Volume: 4, Issue:1 Topics: Alkylating Agents; Animals; Antineoplastic Agents; Bleomycin; Camptothecin; Cell Division; Cytarabine; Deferoxamine; Diamines; DNA, Neoplasm; Doxorubicin; Drug Therapy, Combination; Leukemia L1210; Macromolecular Substances; Mice; Neoplasms; Neoplasms, Experimental; Nitrosourea Compounds; Purine Nucleotides; Ribonucleotide Reductases; Thioguanine; Triazoles	1974
[Recent development of new anticancer drugs in Japan]. Nihon rinsho. Japanese journal of clinical medicine, 1993, Volume: 51, Issue:7 Topics: Aminopterin; Antineoplastic Agents; Camptothecin; Cisplatin; Cytarabine; Irinotecan; Methotrexate; Paclitaxel; Tretinoin; Tubulin Modulators; Vinblastine; Vinorelbine	1993
Liposomal encapsulated anti-cancer drugs. Anti-cancer drugs, 2005, Volume: 16, Issue:7 Topics: Animals; Anthracyclines; Antineoplastic Agents; Camptothecin; Cardiomyopathies; Clinical Trials as Topic; Cytarabine; Humans; Liposomes; Neoplasms; Platinum Compounds; Vincristine	2005

Trials

1 trial(s) available for cytarabine and camptothecin

Article	Year
Sequential administration of irinotecan and cytarabine in the treatment of relapsed and refractory acute myeloid leukemia. Cancer chemotherapy and pharmacology, 2006, Volume: 57, Issue:1 Topics: Acute Disease; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Camptothecin; Cytarabine; DNA Damage; DNA Topoisomerases, Type I; DNA, Neoplasm; Dose-Response Relationship, Drug; Drug Synergism; Female; HL-60 Cells; Humans; Irinotecan; Leukemia, Myeloid; Male; Middle Aged; Recurrence	2006

Article

Year

Sequential administration of irinotecan and cytarabine in the treatment of relapsed and refractory acute myeloid leukemia.

Cancer chemotherapy and pharmacology, 2006, Volume: 57, Issue:1

Topics: Acute Disease; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Camptothecin; Cytarabine; DNA Damage; DNA Topoisomerases, Type I; DNA, Neoplasm; Dose-Response Relationship, Drug; Drug Synergism; Female; HL-60 Cells; Humans; Irinotecan; Leukemia, Myeloid; Male; Middle Aged; Recurrence

2006

Other Studies

42 other study(ies) available for cytarabine and camptothecin

Article	Year
Design, synthesis, and biological evaluation of analogues of the antitumor agent, 2-(4-[(7-chloro-2-quinoxalinyl)oxy]phenoxy)propionic acid (XK469). Journal of medicinal chemistry, 2001, May-24, Volume: 44, Issue:11 Topics: Animals; Antineoplastic Agents; Drug Design; Drug Screening Assays, Antitumor; Humans; Mice; Quinoxalines; Stereoisomerism; Structure-Activity Relationship; Transplantation, Heterologous; Tumor Cells, Cultured	2001
Structure-activity relationship and molecular mechanisms of ethyl 2-amino-4-(2-ethoxy-2-oxoethyl)-6-phenyl-4h-chromene-3-carboxylate (sha 14-1) and its analogues. Journal of medicinal chemistry, 2009, Oct-08, Volume: 52, Issue:19 Topics: Apoptosis; Benzopyrans; Camptothecin; Cell Line, Tumor; Drug Resistance, Neoplasm; Humans; Leukemia; Mitoxantrone; Structure-Activity Relationship	2009
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species. Chemical research in toxicology, 2010, Volume: 23, Issue:1 Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship	2010
A multifactorial approach to hepatobiliary transporter assessment enables improved therapeutic compound development. Toxicological sciences : an official journal of the Society of Toxicology, 2013, Volume: 136, Issue:1 Topics: Animals; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Transport; Chemical and Drug Induced Liver Injury; Cluster Analysis; Drug-Related Side Effects and Adverse Reactions; Humans; Liver; Male; Multidrug Resistance-Associated Proteins; Pharmacokinetics; Rats; Rats, Sprague-Dawley; Recombinant Proteins; Risk Assessment; Risk Factors; Toxicity Tests	2013
In vitro synthesis of DNA in nuclei isolated from herpes simplex virus-infected cells, untreated and treated with metabolic inhibitors. Virology, 1975, Volume: 63, Issue:1 Topics: Adenine Nucleotides; Animals; Anti-Bacterial Agents; Camptothecin; Cell Line; Cell Nucleus; Centrifugation, Density Gradient; Culture Media; Cytarabine; Cytosine Nucleotides; Deoxyadenosines; DNA; DNA, Viral; Guanine Nucleotides; Haplorhini; Hydroxyurea; Kidney; Magnesium; Simplexvirus; Sucrose; Thymine Nucleotides; Tritium; Virus Replication	1975
The effects of inhibitors of nucleic acid and protein synthesis on the replication of Spodoptera frugiperda nuclear polyhedrosis virus in cultured Spodoptera frugiperda cells. Intervirology, 1976, Volume: 7, Issue:6 Topics: Camptothecin; Cell Line; Cycloheximide; Cytarabine; Dactinomycin; Insect Viruses; Insecta; Puromycin; Rifampin; Virus Replication	1976
Differentiation of thymocytes: evidence that induction of the surface phenotype requires transcription and translation. Journal of immunology (Baltimore, Md. : 1950), 1976, Volume: 116, Issue:5 Topics: Animals; Camptothecin; Cell Differentiation; Cycloheximide; Cytarabine; Dactinomycin; Deoxyadenosines; DNA; Hydroxyurea; In Vitro Techniques; Macromolecular Substances; Mice; Mice, Inbred Strains; Phenotype; Protein Biosynthesis; Protein Precursors; Puromycin; RNA; T-Lymphocytes; Thymus Extracts; Transcription, Genetic	1976
Effects of cytosine arabinoside, daunomycin, mithramycin, azacytidine, adriamycin, and camptothecin on mammalian cell cycle traverse. Cancer research, 1972, Volume: 32, Issue:12 Topics: Animals; Antineoplastic Agents; Autoradiography; Azacitidine; Camptothecin; Cell Division; Cell Line; Cricetinae; Cytarabine; Daunorubicin; DNA; DNA Replication; Doxorubicin; Mitosis; Plicamycin; Thymidine; Tritium	1972
Use of flow microfluorometry in detailed analysis of effects of chemical agents on cell cycle progression. Cancer research, 1972, Volume: 32, Issue:12 Topics: Animals; Antineoplastic Agents; Autoradiography; Bleomycin; Camptothecin; Cell Division; Cell Line; Cricetinae; Cytarabine; DNA Replication; Fluorometry; Hydroxyurea; Mitosis; Thymidine; Time Factors; Tritium	1972
The enhanced therapeutic effect of cis-platinum (II) diamminodichloride against L1210 leukemia when combined with cyclophosphamide or 1,2-bis(3,5-dioxopiperazine-1-yl)propane or several other antitumor agents. Chemotherapy, 1973, Volume: 18, Issue:3 Topics: Amines; Animals; Antineoplastic Agents; Azacitidine; Camptothecin; Carmustine; Chlorides; Cyclophosphamide; Cytarabine; Drug Synergism; Emetine; Fluorouracil; Ketones; Leukemia L1210; Male; Methotrexate; Mice; Mice, Inbred C57BL; Mice, Inbred DBA; Piperazines; Platinum; Propane; Time Factors	1973
Potentially useful combinations of chemotherapy detected in mouse tumor systems. Cancer chemotherapy reports. Part 2, 1974, Volume: 4, Issue:1 Topics: Acetylcysteine; Animals; Antineoplastic Agents; Azauridine; Bleomycin; Camptothecin; Cyclic P-Oxides; Cyclophosphamide; Cytarabine; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Synergism; Drug Therapy, Combination; Ethylamines; Fluorouracil; Imidazoles; Leukemia L1210; Lung Neoplasms; Methotrexate; Mice; Neoplasms, Experimental; Oxazines; Piperazines; Procarbazine; Propane; Triazenes	1974
Frozen DON cells as a source for a cell cycle assay of antitumor agents. Experimental cell research, 1974, Volume: 83, Issue:1 Topics: Alkaloids; Animals; Antibiotics, Antineoplastic; Antineoplastic Agents; Biological Assay; Camptothecin; Carbazoles; Cell Division; Cell Line; Cell Survival; Cricetinae; Cryoprotective Agents; Cytarabine; Cytological Techniques; Dactinomycin; Dimethyl Sulfoxide; Floxuridine; Formates; Freezing; Glycerol; Hydroxyurea; Lung; Mitosis; Proteins; Pyridines; Ribonucleosides; Thiosemicarbazones; Time Factors	1974
Isolation of herpes simplex virus DNA from virus particles and infected cells by electrophoresis in polyacrylamide gels. The Journal of general virology, 1974, Volume: 25, Issue:1 Topics: Animals; Camptothecin; Carbon Radioisotopes; Cell Fractionation; Cell Line; Cell Nucleus; Centrifugation, Density Gradient; Cytarabine; Cytoplasm; DNA; DNA Replication; DNA, Viral; Electrophoresis, Polyacrylamide Gel; Haplorhini; Hydroxyurea; Kidney; Molecular Weight; Simplexvirus; Thymidine; Tritium	1974
The effect of dose interval on the survival of L1210 leukemic mice treated with DNA synthesis inhibitors. Cancer research, 1973, Volume: 33, Issue:4 Topics: Animals; Antineoplastic Agents; Camptothecin; Cell Division; Cell Survival; Cytarabine; DNA, Neoplasm; Formates; Hydroxyurea; Leukemia L1210; Mice; Mice, Inbred C57BL; Mice, Inbred DBA; Pyridines; Thiosemicarbazones; Thymidine; Time Factors	1973
Cell-kill kinetics of several S-phase-specific drugs. Cancer research, 1973, Volume: 33, Issue:4 Topics: Animals; Antineoplastic Agents; Camptothecin; Cell Division; Cell Line; Cell Survival; Cricetinae; Cytarabine; DNA, Neoplasm; Formates; Hydroxyurea; Kinetics; Leukemia L1210; Lung; Mice; Neoplasms, Experimental; Pyridines; Thiosemicarbazones; Time Factors	1973
Aspartate-based inhibitor of interleukin-1 beta-converting enzyme prevents antitumor agent-induced apoptosis in human myeloid leukemia U937 cells. Biochemical and biophysical research communications, 1995, Apr-26, Volume: 209, Issue:3 Topics: Antineoplastic Agents; Apoptosis; Aspartic Acid; Camptothecin; Caspase 1; Cell Cycle; Cell Line; Cysteine Endopeptidases; Cytarabine; DNA, Neoplasm; Doxorubicin; Etoposide; Humans; Kinetics; Leukemia, Myeloid; Time Factors; Tumor Cells, Cultured	1995
Activation of protein kinase Cdelta in human myeloid leukemia cells treated with 1-beta-D-arabinofuranosylcytosine. Blood, 1996, Mar-01, Volume: 87, Issue:5 Topics: Amino Acid Sequence; Apoptosis; Camptothecin; Cytarabine; DNA Damage; Endopeptidases; Enzyme Activation; Genes, jun; Humans; Intracellular Signaling Peptides and Proteins; Isoenzymes; Leukemia, Myeloid; Lymphoma, Large B-Cell, Diffuse; Membrane Proteins; Mitomycin; Molecular Sequence Data; Myelin Basic Protein; Myristoylated Alanine-Rich C Kinase Substrate; Neoplasm Proteins; Neoplastic Stem Cells; Nucleosomes; Phosphorylation; Protein Kinase C; Protein Kinase C-delta; Protein Processing, Post-Translational; Proteins; Signal Transduction; Substrate Specificity; Tumor Cells, Cultured	1996
Induction of apoptosis by camptothecin and topotecan. Annals of the New York Academy of Sciences, 1996, Dec-13, Volume: 803 Topics: Antineoplastic Agents, Phytogenic; Apoptosis; Bone Marrow; Camptothecin; Cell Cycle; Cytarabine; DNA Damage; Enzyme Inhibitors; HL-60 Cells; Humans; Leukemia; Topotecan	1996
Phase I clinical and laboratory evaluation of topotecan and cytarabine in patients with acute leukemia. Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 1997, Volume: 15, Issue:1 Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Apoptosis; Blast Crisis; Camptothecin; Cytarabine; Drug Administration Schedule; Female; Humans; Leukemia, Myelogenous, Chronic, BCR-ABL Positive; Leukemia, Myeloid, Acute; Male; Middle Aged; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Topotecan	1997
[Involvement of ICE/CED 3 family proteases in antitumor agent-induced apoptosis]. Gan to kagaku ryoho. Cancer & chemotherapy, 1997, Volume: 24, Issue:2 Topics: Antineoplastic Agents; Apoptosis; Camptothecin; Caspase 1; Cycloheximide; Cysteine Endopeptidases; Cytarabine; Doxorubicin; Humans; Leukemia; Tumor Cells, Cultured; Tumor Necrosis Factor-alpha	1997
Apoptosis-resistant phenotype selected by alternating exposure to camptothecin and etoposide. Experimental cell research, 1997, Aug-25, Volume: 235, Issue:1 Topics: Antineoplastic Agents; Apoptosis; Arabinofuranosylcytosine Triphosphate; ATP Binding Cassette Transporter, Subfamily B, Member 1; bcl-X Protein; Calcimycin; Camptothecin; Clone Cells; Cycloheximide; Cytarabine; DNA Fragmentation; Drug Resistance, Neoplasm; Etoposide; HL-60 Cells; Humans; Hydroxyurea; Kinetics; Nucleosomes; Phenotype; Proto-Oncogene Proteins c-bcl-2; Ultraviolet Rays	1997
NADH dehydrogenase deficiency in an apoptosis-resistant mutant isolated from a human HL-60 leukemia cell line. Cancer research, 1997, Dec-01, Volume: 57, Issue:23 Topics: Antineoplastic Agents; Apoptosis; Calcimycin; Camptothecin; Cell Division; Clone Cells; Cloning, Molecular; Cytarabine; Deoxyglucose; Etoposide; Glucose; HL-60 Cells; Humans; Hydroxyurea; Macromolecular Substances; Mitochondria; Mutagenesis; NADH Dehydrogenase; Transcription, Genetic; Ultraviolet Rays	1997
Cyclin-dependent kinases participate in death of neurons evoked by DNA-damaging agents. The Journal of cell biology, 1998, Oct-19, Volume: 143, Issue:2 Topics: Animals; Antimetabolites, Antineoplastic; Antineoplastic Agents, Phytogenic; Apoptosis; Camptothecin; CDC2-CDC28 Kinases; Cell Cycle; Cells, Cultured; Cerebral Cortex; Cyclin D1; Cyclin-Dependent Kinase 2; Cyclin-Dependent Kinase 4; Cyclin-Dependent Kinase 6; Cyclin-Dependent Kinases; Cytarabine; DNA Damage; Enzyme Activation; Gene Expression Regulation, Viral; Neurons; Protein Serine-Threonine Kinases; Proto-Oncogene Proteins; Rats; Rats, Sprague-Dawley; Sindbis Virus; Superior Cervical Ganglion; Ultraviolet Rays	1998
Evidence against a direct role for the induction of c-jun expression in the mediation of drug-induced apoptosis in human acute leukemia cells. Clinical cancer research : an official journal of the American Association for Cancer Research, 1995, Volume: 1, Issue:5 Topics: Antineoplastic Agents; Apoptosis; Camptothecin; Cisplatin; Cytarabine; Etoposide; Gene Expression Regulation, Neoplastic; Genes, bcl-2; Genes, jun; HL-60 Cells; Humans; Leukemia, B-Cell; Mitoxantrone; Paclitaxel; Proto-Oncogene Proteins c-bcl-2; Proto-Oncogene Proteins c-jun; Recombinant Proteins; Transfection; Tumor Cells, Cultured	1995
Bcl-2 expression correlates with apoptosis induction but not tumor growth delay in transplantable murine lymphomas treated with different chemotherapy drugs. Cancer chemotherapy and pharmacology, 1999, Volume: 44, Issue:5 Topics: Animals; Antineoplastic Agents; Apoptosis; Camptothecin; Cisplatin; Cyclophosphamide; Cytarabine; Doxorubicin; Etoposide; Female; Gene Expression Regulation, Neoplastic; Genes, bcl-2; Lymphoma; Male; Mice; Mice, Inbred C3H; Proto-Oncogene Proteins c-bcl-2	1999
Proteolytic activation of protein kinase C delta and epsilon by caspase-3 in U937 cells during chemotherapeutic agent-induced apoptosis. Cellular signalling, 1999, Volume: 11, Issue:11 Topics: Antineoplastic Agents; Apoptosis; Camptothecin; Caspase 3; Caspase Inhibitors; Caspases; Cysteine Proteinase Inhibitors; Cytarabine; Enzyme Activation; Etoposide; fas Receptor; Humans; Isoenzymes; Oligopeptides; Protein Kinase C; Protein Kinase C-delta; Protein Kinase C-epsilon; Tetradecanoylphorbol Acetate; U937 Cells	1999
Induction of topoisomerase I cleavage complexes by 1-beta -D-arabinofuranosylcytosine (ara-C) in vitro and in ara-C-treated cells. Proceedings of the National Academy of Sciences of the United States of America, 2000, Feb-15, Volume: 97, Issue:4 Topics: Animals; Antineoplastic Agents; Camptothecin; Cytarabine; DNA; DNA Topoisomerases, Type I; Drug Resistance; Enzyme Induction; Humans; Mice; Molecular Structure; Tumor Cells, Cultured	2000
An MCL1-overexpressing Burkitt lymphoma subline exhibits enhanced survival on exposure to serum deprivation, topoisomerase inhibitors, or staurosporine but remains sensitive to 1-beta-D-arabinofuranosylcytosine. Cancer research, 2002, Feb-01, Volume: 62, Issue:3 Topics: Antimetabolites, Antineoplastic; Apoptosis; Burkitt Lymphoma; Camptothecin; Cell Survival; Culture Media, Serum-Free; Cytarabine; Drug Resistance, Multiple; Drug Resistance, Neoplasm; Enzyme Inhibitors; Etoposide; Humans; Myeloid Cell Leukemia Sequence 1 Protein; Neoplasm Proteins; Proto-Oncogene Proteins c-bcl-2; Staurosporine; Topoisomerase Inhibitors; Tumor Cells, Cultured	2002
Alteration in copy numbers of genes as a mechanism for acquired drug resistance. Cancer research, 2004, Feb-15, Volume: 64, Issue:4 Topics: Apoptosis; ATP-Binding Cassette Transporters; Camptothecin; Cell Line, Tumor; Cytarabine; Drug Resistance, Neoplasm; Etoposide; Gene Amplification; Gene Dosage; Genes, bcl-2; Humans	2004
Rad9 protects cells from topoisomerase poison-induced cell death. The Journal of biological chemistry, 2004, Apr-30, Volume: 279, Issue:18 Topics: Animals; Apoptosis; Camptothecin; Cell Cycle Proteins; Cytarabine; DNA Damage; DNA Topoisomerases; Embryo, Mammalian; Etoposide; Humans; Mice; Mice, Knockout; Protective Agents; Stem Cells; Topoisomerase Inhibitors; Transfection; Transgenes	2004
Homologous recombination is a highly conserved determinant of the synergistic cytotoxicity between cisplatin and DNA topoisomerase I poisons. Molecular cancer therapeutics, 2004, Volume: 3, Issue:4 Topics: Animals; Camptothecin; Cell Survival; CHO Cells; Cisplatin; Cricetinae; Cricetulus; Cytarabine; DNA Damage; DNA Repair; DNA Topoisomerases, Type I; DNA-Binding Proteins; Drug Synergism; Enzyme Inhibitors; Rad52 DNA Repair and Recombination Protein; Recombination, Genetic; Saccharomyces cerevisiae; Saccharomyces cerevisiae Proteins; Schizosaccharomyces; Topoisomerase I Inhibitors; X-Rays	2004
An in vitro model system that can differentiate the stages of DNA replication affected by anticancer agents. Biochemical pharmacology, 2004, Jul-01, Volume: 68, Issue:1 Topics: Antineoplastic Agents; Arabinofuranosylcytosine Triphosphate; Camptothecin; Cytarabine; DNA Replication; DNA-Directed DNA Polymerase; DNA, Viral; Doxorubicin; Electrophoresis, Agar Gel; Humans; Multienzyme Complexes; Simian virus 40	2004
Platinated DNA adducts enhance poisoning of DNA topoisomerase I by camptothecin. The Journal of biological chemistry, 2004, Dec-24, Volume: 279, Issue:52 Topics: Antineoplastic Agents, Phytogenic; Breast Neoplasms; Camptothecin; Cisplatin; Colonic Neoplasms; Cytarabine; DNA; DNA Adducts; DNA Topoisomerases, Type I; Drug Synergism; Enzyme Inhibitors; Female; Humans; Models, Molecular; Ovarian Neoplasms; Platinum Compounds; Topoisomerase I Inhibitors; Topotecan; Tumor Cells, Cultured	2004
Cytotoxic effects of histone deacetylase inhibitor FK228 (depsipeptide, formally named FR901228) in combination with conventional anti-leukemia/lymphoma agents against human leukemia/lymphoma cell lines. Investigational new drugs, 2007, Volume: 25, Issue:1 Topics: Antineoplastic Agents; Apoptosis; Benzamides; Camptothecin; Carboplatin; Cell Line, Tumor; Cell Survival; Cyclophosphamide; Cytarabine; Depsipeptides; Dose-Response Relationship, Drug; Doxorubicin; Drug Synergism; Etoposide; Histone Deacetylase Inhibitors; HL-60 Cells; Humans; Imatinib Mesylate; Irinotecan; K562 Cells; Leukemia; Lymphoma; Mercaptopurine; Piperazines; Pyrimidines; Time Factors	2007
Ratiometric dosing of anticancer drug combinations: controlling drug ratios after systemic administration regulates therapeutic activity in tumor-bearing mice. Molecular cancer therapeutics, 2006, Volume: 5, Issue:7 Topics: Animals; Antineoplastic Combined Chemotherapy Protocols; Camptothecin; Cell Line, Tumor; Cisplatin; Cytarabine; Daunorubicin; Dose-Response Relationship, Drug; Drug Synergism; Floxuridine; Humans; Irinotecan; Liposomes; Mice; Neoplasms; Xenograft Model Antitumor Assays	2006
Anti proliferative activity of ELACY (CP-4055) in combination with cloretazine (VNP40101M), idarubicin, gemcitabine, irinotecan and topotecan in human leukemia and lymphoma cells. Leukemia & lymphoma, 2008, Volume: 49, Issue:4 Topics: Antineoplastic Combined Chemotherapy Protocols; Camptothecin; Cell Line, Tumor; Cytarabine; Deoxycytidine; Drug Interactions; Drug Screening Assays, Antitumor; Gemcitabine; Humans; Hydrazines; Idarubicin; Irinotecan; Leukemia; Lymphoma; Sulfonamides; Topotecan	2008
Wipe sampling procedure coupled to LC-MS/MS analysis for the simultaneous determination of 10 cytotoxic drugs on different surfaces. Analytical and bioanalytical chemistry, 2012, Volume: 402, Issue:8 Topics: Antineoplastic Agents; Camptothecin; Chromatography, Liquid; Cyclophosphamide; Cytarabine; Deoxycytidine; Doxorubicin; Epirubicin; Etoposide; Gemcitabine; Ifosfamide; Irinotecan; Methotrexate; Organophosphorus Compounds; Surface Properties; Tandem Mass Spectrometry; Vincristine	2012
Preclinical development of the novel Chk1 inhibitor SCH900776 in combination with DNA-damaging agents and antimetabolites. Molecular cancer therapeutics, 2012, Volume: 11, Issue:2 Topics: Antimetabolites; Antineoplastic Agents; Blotting, Western; Camptothecin; Cell Cycle Checkpoints; Cell Line; Cell Line, Tumor; Cell Proliferation; Cell Survival; Checkpoint Kinase 1; Cytarabine; Deoxycytidine; DNA Breaks, Double-Stranded; DNA Damage; Dose-Response Relationship, Drug; Drug Screening Assays, Antitumor; Drug Synergism; Flow Cytometry; Gemcitabine; Humans; Hydroxyurea; Irinotecan; Molecular Structure; Phosphorylation; Protein Kinase Inhibitors; Protein Kinases; Pyrazoles; Pyrimidines; Staurosporine	2012
Effectiveness of a Closed-System Transfer Device in Reducing Surface Contamination in a New Antineoplastic Drug-Compounding Unit: A Prospective, Controlled, Parallel Study. PloS one, 2016, Volume: 11, Issue:7 Topics: Antineoplastic Agents; Camptothecin; Cyclophosphamide; Cytarabine; Deoxycytidine; Drug Compounding; Drug Contamination; Fluorouracil; Ganciclovir; Gemcitabine; Humans; Ifosfamide; Irinotecan; Methotrexate; Occupational Exposure; Prospective Studies	2016
TDP1 is Critical for the Repair of DNA Breaks Induced by Sapacitabine, a Nucleoside also Targeting ATM- and BRCA-Deficient Tumors. Molecular cancer therapeutics, 2017, Volume: 16, Issue:11 Topics: Arabinonucleosides; BRCA2 Protein; Camptothecin; Colorectal Neoplasms; Cytarabine; Cytosine; DNA Breaks, Single-Stranded; DNA Damage; DNA Repair; DNA Replication; Gene Expression Regulation, Neoplastic; HCT116 Cells; Humans; Phosphoric Diester Hydrolases; Poly (ADP-Ribose) Polymerase-1	2017
Rational Design of a New Self-Codelivery System from Redox-Sensitive Camptothecin-Cytarabine Conjugate Assembly for Effectively Synergistic Anticancer Therapy. Advanced healthcare materials, 2017, Volume: 6, Issue:24 Topics: Animals; Antineoplastic Agents, Phytogenic; Apoptosis; Camptothecin; Cell Line, Tumor; Cytarabine; Disease Models, Animal; Drug Delivery Systems; Drug Liberation; Drug Synergism; Female; Glutathione; HT29 Cells; Human Umbilical Vein Endothelial Cells; Humans; Magnetic Resonance Imaging; Mice; Nanoparticles	2017
Monophosphorylation by deoxycytidine kinase affects apparent cellular uptake of decitabine in HCT116 colon cancer cells. Drug metabolism and pharmacokinetics, 2017, Volume: 32, Issue:6 Topics: Antimetabolites, Antineoplastic; Azacitidine; Camptothecin; Colonic Neoplasms; Cytarabine; Decitabine; Deoxycytidine; Deoxycytidine Kinase; Equilibrative Nucleoside Transporter 1; Etoposide; Gemcitabine; HCT116 Cells; Humans; Irinotecan; Phosphorylation	2017