cytarabine and caffeine

cytarabine has been researched along with caffeine in 49 studies

Research

Studies (49)

TimeframeStudies, this research(%)All Research%
pre-199025 (51.02)18.7374
1990's12 (24.49)18.2507
2000's8 (16.33)29.6817
2010's4 (8.16)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
González-Díaz, H; Orallo, F; Quezada, E; Santana, L; Uriarte, E; Viña, D; Yáñez, M1
Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A1
Choi, SS; Contrera, JF; Hastings, KL; Kruhlak, NL; Sancilio, LF; Weaver, JL; Willard, JM1
Ambroso, JL; Ayrton, AD; Baines, IA; Bloomer, JC; Chen, L; Clarke, SE; Ellens, HM; Harrell, AW; Lovatt, CA; Reese, MJ; Sakatis, MZ; Taylor, MA; Yang, EY1
Afshari, CA; Chen, Y; Dunn, RT; Hamadeh, HK; Kalanzi, J; Kalyanaraman, N; Morgan, RE; van Staden, CJ1
Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K1
Nakanishi, Y; Schneider, EL1
Johnson, RT; Schor, SL; Waldren, CA1
Casto, BC; Dipaolo, JA; Janosko, N; Pieczynski, WJ1
Schöneich, J; Wobus, AM1
Antoccia, A; Catena, C; Palitti, F; Raggi, T; Tanzarella, C1
Mitsumoto, Y; Mohri, T; Ohkubo, T1
Chung, HW; Morgan, WF; Phillips, JW; Preston, RJ; Winegar, RA1
Sakamoto-Hojo, ET; Takahashi, CS1
Zaborowska, D; Zuk, J1
Cortés, F; Mateos, S; Ortiz, T; Piñero, J2
Maemori, M; Matsuda, Y; Tobari, I1
Botet, J; Dougherty, JB; Kelsen, D; Kemeny, N; Magill, G; Niedzwiecki, D1
Genter, EI; Mikhel'son, VM; Zhestianikov, VD1
Maemori, M; Matsuda, Y; Seki, N; Tobari, I1
Matsuda, Y; Tobari, I3
Chebotarev, AN; Golovina, ME; Smirnova, TD1
Benoit, B; DaSilva, V; Hugenholtz, H; Maroun, J; Richard, M; Russell, N; Stewart, DJ; Verma, S1
Bantle, JA; Dawson, DA1
Kapp, LN; Painter, RB; Young, BR1
Kyriazis, AA; Kyriazis, AP; Yagoda, A1
Bedford, JS; Bender, MA; Griggs, HG1
Arlett, CF1
Natarajan, AT; Obe, G1
Dozi-Vassiliades, J; Granitsas, A; Mourelatos, D; Tsigalidou-Balla, V1
Filatov, MV; Sheĭkna, TA1
Gantt, R; Jones, GM; Parshad, R; Sanford, KK; Tarone, RE1
Fujiwara, Y; Ichihashi, M1
Kozuka, H; Miyahara, T; Sakaguchi, M; Yamada, H1
Medeiros M das, G; Takahashi, CS1
Dubinina, LG1
Melnick, LK; Nee, LE; Parshad, RP; Price, FM; Robbins, JH; Sanford, KK; Schapiro, MB; Tarone, RE1
Christensen, C; Deppe, G; Lawrence, WD; Ruan, H; Saunders, DE; Wappler, NL1
Erdoğan, D; Kadioğlu, D; Peker, T1
Ahmed, S; Arlauskas, P; Du, W; Gordon, C; Kellogg, C; Shields, AF; Vaitkevicius, VK; Zalupski, MM1
Mizutani, S; Oshimi, K; Sasaki, M; Sugimoto, K; Takagi, M; Tamayose, K; Yamada, K1
Arutyunyan, RM; Cleaver, JE; Coriell, L; Greene, AE; Kaufmann, WK; Sarkisian, T1
Piwnica-Worms, H; Zhao, H1
Buzello, C; Nguyen, M; Sun, D; Urrabaz, R1
Adsay, V; Al-Sukhun, S; Ben-Josef, E; Forman, JD; Heilbrun, LK; Levin, K; Philip, PA; Shields, AF; Soulen, R; Vaitkevicius, VK; Weaver, D; Zalupski, MM1
Horio, T; Kaminishi, Y; Katsuma, S; Ohgi, T; Takagaki, K; Tanaka, T; Yano, J1

Reviews

2 review(s) available for cytarabine and caffeine

ArticleYear
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
    Drug discovery today, 2016, Volume: 21, Issue:4

    Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk

2016
Mechanisms of chromosomal aberration production. 3. Chemicals and ionizing radiation.
    Mutation research, 1974, Volume: 23, Issue:2

    Topics: Alkylating Agents; Animals; Caffeine; Chromosome Aberrations; Cyanides; Cytarabine; Deoxyadenosines; DNA; DNA Repair; DNA Replication; DNA, Single-Stranded; Floxuridine; Hydroxyurea; Mitosis; Models, Biological; Mutagens; Radiation Genetics; Recombination, Genetic; Streptonigrin; Theobromine; Theophylline

1974

Trials

3 trial(s) available for cytarabine and caffeine

ArticleYear
Advanced pancreatic cancer: a phase I-II trial of cisplatin, high-dose cytarabine, and caffeine.
    Journal of the National Cancer Institute, 1989, Nov-15, Volume: 81, Issue:22

    Topics: Acute Disease; Adenocarcinoma; Antineoplastic Combined Chemotherapy Protocols; Caffeine; Cisplatin; Clinical Trials as Topic; Cytarabine; Drug Administration Schedule; Drug Evaluation; Female; Humans; Male; Middle Aged; Pancreatic Neoplasms; Time Factors

1989
Cisplatin, cytarabine, caffeine, and continuously infused 5-fluorouracil (PACE) in the treatment of advanced pancreatic carcinoma: a phase II study.
    American journal of clinical oncology, 2000, Volume: 23, Issue:4

    Topics: Adenocarcinoma; Adult; Aged; Antimetabolites, Antineoplastic; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Biomarkers, Tumor; CA-19-9 Antigen; Caffeine; Cisplatin; Confidence Intervals; Cytarabine; Female; Fluorouracil; Humans; Male; Middle Aged; Neutropenia; Pancreatic Neoplasms; Phosphodiesterase Inhibitors; Remission Induction; Survival Rate; Thrombocytopenia

2000
Chemoradiotherapy in the treatment of regional pancreatic carcinoma: a phase II study.
    American journal of clinical oncology, 2003, Volume: 26, Issue:6

    Topics: Adenocarcinoma; Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Caffeine; Cisplatin; Combined Modality Therapy; Cytarabine; Female; Fluorouracil; Humans; Male; Middle Aged; Neoadjuvant Therapy; Pancreatic Neoplasms; Radiotherapy Dosage; Survival Analysis

2003

Other Studies

44 other study(ies) available for cytarabine and caffeine

ArticleYear
Quantitative structure-activity relationship and complex network approach to monoamine oxidase A and B inhibitors.
    Journal of medicinal chemistry, 2008, Nov-13, Volume: 51, Issue:21

    Topics: Computational Biology; Drug Design; Humans; Isoenzymes; Molecular Structure; Monoamine Oxidase; Monoamine Oxidase Inhibitors; Quantitative Structure-Activity Relationship

2008
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
    Chemical research in toxicology, 2010, Volume: 23, Issue:1

    Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship

2010
Development of a phospholipidosis database and predictive quantitative structure-activity relationship (QSAR) models.
    Toxicology mechanisms and methods, 2008, Volume: 18, Issue:2-3

    Topics:

2008
Preclinical strategy to reduce clinical hepatotoxicity using in vitro bioactivation data for >200 compounds.
    Chemical research in toxicology, 2012, Oct-15, Volume: 25, Issue:10

    Topics: Chemical and Drug Induced Liver Injury; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Decision Trees; Drug Evaluation, Preclinical; Drug-Related Side Effects and Adverse Reactions; Glutathione; Humans; Liver; Pharmaceutical Preparations; Protein Binding

2012
A multifactorial approach to hepatobiliary transporter assessment enables improved therapeutic compound development.
    Toxicological sciences : an official journal of the Society of Toxicology, 2013, Volume: 136, Issue:1

    Topics: Animals; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Transport; Chemical and Drug Induced Liver Injury; Cluster Analysis; Drug-Related Side Effects and Adverse Reactions; Humans; Liver; Male; Multidrug Resistance-Associated Proteins; Pharmacokinetics; Rats; Rats, Sprague-Dawley; Recombinant Proteins; Risk Assessment; Risk Factors; Toxicity Tests

2013
In vivo sister-chromatid exchange: a sensitive measure of DNA damage.
    Mutation research, 1979, Volume: 60, Issue:3

    Topics: 4-Nitroquinoline-1-oxide; Animals; Bromodeoxyuridine; Caffeine; Chromosomes; Crossing Over, Genetic; Cytarabine; Daunorubicin; DNA; Drug Evaluation, Preclinical; Ethyl Methanesulfonate; Genetic Techniques; Male; Methylnitronitrosoguanidine; Mice; Mice, Inbred C57BL; Mitomycins; Mutagens; X-Rays

1979
Changes in the organization of chromosomes during the cell cycle: response to ultraviolet light.
    Journal of cell science, 1975, Volume: 17, Issue:3

    Topics: Autoradiography; Caffeine; Cell Division; Cell Fusion; Cell Survival; Chromosomes; Cytarabine; DNA, Neoplasm; Floxuridine; HeLa Cells; Humans; Hydroxyurea; Mitosis; Radiation Effects; Thymidine; Tritium; Ultraviolet Rays

1975
Significance of treatment interval and DNA repair in the enhancement of viral transformation by chemical carcinogens and mutagens.
    Chemico-biological interactions, 1976, Volume: 13, Issue:2

    Topics: 9,10-Dimethyl-1,2-benzanthracene; Acetoxyacetylaminofluorene; Adenoviridae; Aflatoxins; Benzopyrenes; Caffeine; Carcinogens; Cell Line; Cell Transformation, Neoplastic; Cytarabine; DNA Repair; DNA Replication; Methyl Methanesulfonate; Methylcholanthrene; Methylnitronitrosoguanidine; Mutagens; Oncogenic Viruses; Propiolactone

1976
[A cytological test system for the routine determination of mutagenicity].
    Die Pharmazie, 1977, Volume: 32, Issue:3

    Topics: Ascitic Fluid; Caffeine; Cells, Cultured; Chromosome Aberrations; Cytarabine; Hydrazines; Isonicotinic Acids; Mechlorethamine; Methods; Mutation; Netropsin

1977
The yield of fission neutron-induced chromatid aberrations in G2-stage human lymphocytes: effect of caffeine, hydroxyurea and cytosine arabinoside post-irradiation.
    International journal of radiation biology, 1992, Volume: 62, Issue:5

    Topics: Caffeine; Chromosome Aberrations; Cytarabine; DNA Damage; DNA Repair; G2 Phase; Humans; Hydroxyurea; Lymphocytes; Neutrons

1992
Characterization of the uptake of adenosine by cultured rat hippocampal cells and inhibition of the uptake by xanthine derivatives.
    Neuroscience letters, 1991, Dec-09, Volume: 133, Issue:2

    Topics: 2-Chloroadenosine; Adenosine; Affinity Labels; Animals; Biological Transport; Caffeine; Cells, Cultured; Cytarabine; Dipyridamole; Embryo, Mammalian; Hippocampus; Kinetics; Neuroglia; Neurons; Pentoxifylline; Rats; Sodium; Theophylline; Thioinosine; Tritium; Xanthines

1991
Modulation of restriction enzyme-induced damage by chemicals that interfere with cellular responses to DNA damage: a cytogenetic and pulsed-field gel analysis.
    Radiation research, 1991, Volume: 125, Issue:1

    Topics: Animals; Aphidicolin; Benzamides; Caffeine; Cytarabine; Deoxyribonucleases, Type II Site-Specific; Diterpenes; DNA Damage

1991
Clastogenic action of ellipticine over the cell cycle of human lymphocytes and influence of posttreatments with caffeine and ara-C at G2.
    Mutation research, 1991, Volume: 248, Issue:1

    Topics: Caffeine; Cell Cycle; Chromosome Aberrations; Cytarabine; DNA; DNA Repair; Drug Synergism; Ellipticines; G2 Phase; Humans; Mutagens; Sister Chromatid Exchange

1991
The effect of DNA replication on mutation of the Saccharomyces cerevisiae CDC8 gene.
    Current genetics, 1990, Volume: 17, Issue:4

    Topics: Arabinonucleotides; Buffers; Caffeine; Cycloheximide; Cytarabine; Cytidine Monophosphate; DNA Replication; DNA, Fungal; Genes, Fungal; Hydroxyurea; Mutation; Phenotype; Phosphates; Saccharomyces cerevisiae; Ultraviolet Rays

1990
G2 effects of DNA-repair inhibitors on chromatid-type aberrations in root-tip cells treated with maleic hydrazide and mitomycin C.
    Mutation research, 1989, Volume: 226, Issue:2

    Topics: Caffeine; Cell Cycle; Chromosome Aberrations; Chromosomes; Cytarabine; DNA Damage; DNA Repair; Floxuridine; Hydroxyurea; In Vitro Techniques; Interphase; Maleic Hydrazide; Mitomycin; Mitomycins; Plants; Pyridazines; Thymidine

1989
Relationship between cell cycle stage in the fertilized egg of mice and repair capacity for X-ray-induced damage in the sperm.
    International journal of radiation biology, 1989, Volume: 56, Issue:3

    Topics: Animals; Benzamides; Caffeine; Cell Cycle; Chromosome Aberrations; Cytarabine; DNA Damage; DNA Repair; Hydroxyurea; Male; Metaphase; Mice; Radiation-Sensitizing Agents; Spermatozoa; Zygote

1989
[UV-induced unscheduled DNA synthesis in differentiated and dedifferentiated lymphocytes from human peripheral blood under the action of DNA-repair and -replication inhibitors].
    Tsitologiia, 1989, Volume: 31, Issue:2

    Topics: Benzamides; Caffeine; Cell Differentiation; Cells, Cultured; Cytarabine; Depression, Chemical; DNA; DNA Repair; DNA Replication; Drug Interactions; Humans; Hydroxyurea; Lymphocytes; Phytohemagglutinins; Ultraviolet Rays

1989
Mechanism of chromosome aberration induction in the mouse egg fertilized with sperm recovered from postmeiotic germ cells treated with methyl methanesulfonate.
    Mutation research, 1989, Volume: 214, Issue:2

    Topics: Animals; Benzamides; Caffeine; Chromosome Aberrations; Cytarabine; Female; Hydroxyurea; Male; Meiosis; Methyl Methanesulfonate; Mice; Mice, Inbred Strains; Mutagens; Ovum; Sister Chromatid Exchange; Spermatozoa; Zygote

1989
Repair capacity of fertilized mouse eggs for X-ray damage induced in sperm and mature oocytes.
    Mutation research, 1989, Volume: 210, Issue:1

    Topics: Animals; Benzamides; Caffeine; Chromosome Aberrations; Chromosome Banding; Cleavage Stage, Ovum; Cytarabine; DNA Repair; Male; Mice; Mitotic Index; Oocytes; Spermatozoa; X-Rays

1989
Effects of caffeine and inhibitors of DNA synthesis on chromatid-type aberrations induced by acetaldehyde in root-tip cells.
    Mutation research, 1987, Volume: 180, Issue:2

    Topics: Acetaldehyde; Caffeine; Cells, Cultured; Chromatids; Chromosome Aberrations; Cytarabine; DNA Replication; Floxuridine; Hydroxyurea; Mutagenicity Tests; Plants

1987
[Simultaneous estimation of sister chromatid exchange and evaluation of cell cycle delay].
    Biulleten' eksperimental'noi biologii i meditsiny, 1988, Volume: 105, Issue:5

    Topics: Animals; Caffeine; Cell Cycle; Cells, Cultured; Cricetinae; Cricetulus; Cytarabine; Hydroxyurea; Mitosis; Sister Chromatid Exchange; Thiotepa

1988
Chromosomal analysis in mouse eggs fertilized in vitro with sperm exposed to ultraviolet light (UV) and methyl and ethyl methanesulfonate (MMS and EMS).
    Mutation research, 1988, Volume: 198, Issue:1

    Topics: Animals; Caffeine; Cell Cycle; Chromosome Aberrations; Cytarabine; Ethyl Methanesulfonate; Female; Fertilization in Vitro; Male; Methyl Methanesulfonate; Mice; Mice, Inbred C3H; Mice, Inbred C57BL; Spermatozoa; Ultraviolet Rays; Zygote

1988
Cytosine arabinoside plus cisplatin and other drugs as chemotherapy for gliomas.
    Seminars in oncology, 1987, Volume: 14, Issue:2 Suppl 1

    Topics: Antineoplastic Combined Chemotherapy Protocols; Brain Neoplasms; Caffeine; Carmustine; Cisplatin; Cytarabine; Drug Synergism; Glioma; Humans; Teniposide

1987
Coadministration of methylxanthines and inhibitor compounds potentiates teratogenicity in Xenopus embryos.
    Teratology, 1987, Volume: 35, Issue:2

    Topics: Abnormalities, Drug-Induced; Animals; Caffeine; Cycloheximide; Cytarabine; Drug Synergism; Embryo, Nonmammalian; Emetine; Fluorouracil; Hydroxyurea; Theobromine; Theophylline; Xanthines; Xenopus laevis

1987
Absence of DNA overreplication in Chinese hamster cells incubated with inhibitors of DNA synthesis.
    Cancer research, 1987, Nov-01, Volume: 47, Issue:21

    Topics: Animals; Bromodeoxyuridine; Caffeine; Cells, Cultured; Centrifugation, Density Gradient; Cricetinae; Cytarabine; DNA; DNA Replication; Gene Amplification; Hydroxyurea

1987
Enhanced therapeutic effect of cis-diamminedichloroplatinum(II) against nude mouse grown human pancreatic adenocarcinoma when combined with 1-beta-D-arabinofuranosylcytosine and caffeine.
    Cancer research, 1985, Volume: 45, Issue:12 Pt 1

    Topics: Adenocarcinoma; Animals; Antineoplastic Combined Chemotherapy Protocols; Caffeine; Cisplatin; Cytarabine; Drug Synergism; Female; Humans; Mice; Mice, Nude; Neoplasm Transplantation; Pancreatic Neoplasms

1985
The influence of post-irradiation conditions on the survival of Chinese hamster cells after gamma-irradiation.
    International journal of radiation biology and related studies in physics, chemistry, and medicine, 1970, Volume: 17, Issue:6

    Topics: Acridines; Animals; Caffeine; Chloramphenicol; Cricetinae; Culture Techniques; Cycloheximide; Cytarabine; Dactinomycin; DNA; Hydroxylamines; Hydroxyurea; Protein Binding; Protein Biosynthesis; Puromycin; Radiation Effects; Temperature; Thymidine

1970
Molecular mechanisms involved in the production of chromosomal aberrations. III. Restriction endonucleases.
    Chromosoma, 1984, Volume: 90, Issue:2

    Topics: Animals; Caffeine; Cell Cycle; Cell Line; Chromosome Aberrations; Cricetinae; Cricetulus; Cytarabine; DNA Restriction Enzymes; Female; Fibroblasts; Karyotyping; Kinetics; Metaphase; Mice; Ovary

1984
Enhancement by methylxanthines of sister-chromatid exchange frequency induced by cytostatics in normal and leukemic human lymphocytes.
    Mutation research, 1983, Volume: 121, Issue:2

    Topics: Caffeine; Cells, Cultured; Crossing Over, Genetic; Cytarabine; Drug Synergism; Humans; Leukemia; Lymphocytes; Mitomycin; Mitomycins; Mutagenicity Tests; Mutagens; Sister Chromatid Exchange; Xanthines

1983
[Caffeine inactivation of mammalian cells in the S phase of the mitotic cycle due to anomalous replicon initiation during the inhibition of the elongation of replicating DNA].
    Tsitologiia, 1984, Volume: 26, Issue:10

    Topics: Animals; Caffeine; Cell Line; Cells, Cultured; Cricetinae; Cricetulus; Cytarabine; DNA; DNA Replication; Gamma Rays; Hydroxyurea; Interphase; Mitosis; Novobiocin; Replicon

1984
Repair of chromosome damage induced by X-irradiation during G2 phase in a line of normal human fibroblasts and its malignant derivative.
    Journal of the National Cancer Institute, 1982, Volume: 69, Issue:2

    Topics: 4-Nitroquinoline-1-oxide; Caffeine; Catalase; Cell Line; Cell Transformation, Neoplastic; Chromosome Aberrations; Cytarabine; DNA Repair; Fibroblasts; Humans; Interphase; Mannitol; Radiation Dosage

1982
Clinical and photobiological characteristics of Japanese xeroderma pigmentosum variant.
    The British journal of dermatology, 1981, Volume: 105, Issue:1

    Topics: Adult; Caffeine; Cells, Cultured; Child; Child, Preschool; Cytarabine; DNA; Dose-Response Relationship, Radiation; Female; Fibroblasts; Humans; Light; Male; Middle Aged; Skin; Ultraviolet Rays; Xeroderma Pigmentosum

1981
Antagonizing effect of triphenyltin chloride on cytosine-1-beta-D-arabinofuranoside potentiation of chromosome aberrations induced by mitomycin C.
    Mutation research, 1994, Volume: 323, Issue:3

    Topics: Animals; Caffeine; CHO Cells; Chromosome Aberrations; Cricetinae; Cytarabine; Drug Antagonism; Drug Synergism; G2 Phase; Hydroxyurea; Mitomycin; Mutagenesis; Organotin Compounds

1994
Effects of treatment with mitoxantrone in combination with novobiocin, caffeine and ara-C on human lymphocytes in culture.
    Mutation research, 1994, May-01, Volume: 307, Issue:1

    Topics: Adult; Caffeine; Cells, Cultured; Cytarabine; DNA Repair; Drug Interactions; Female; Humans; Lymphocytes; Male; Mitoxantrone; Novobiocin

1994
[The effect of inhibitors on induced mutagenesis].
    Genetika, 1993, Volume: 29, Issue:8

    Topics: Aphidicolin; Caffeine; Cell Line; Cytarabine; DNA Replication; G1 Phase; G2 Phase; Hydroxyurea; Mitomycin; Mutagenesis; Seeds

1993
Radiosensitivity and effects of repair inhibitors for X-ray-induced chromosomal damage in mouse zygotes in S and G2 phases.
    International journal of radiation biology, 1995, Volume: 68, Issue:6

    Topics: Animals; Benzamides; Caffeine; Chromosome Aberrations; Cytarabine; DNA Repair; Female; G2 Phase; Male; Mice; Mice, Inbred C3H; Mice, Inbred C57BL; Radiation Tolerance; S Phase; X-Rays; Zygote

1995
Fluorescent light-induced chromatid breaks distinguish Alzheimer disease cells from normal cells in tissue culture.
    Proceedings of the National Academy of Sciences of the United States of America, 1996, May-14, Volume: 93, Issue:10

    Topics: Alzheimer Disease; Caffeine; Case-Control Studies; Cells, Cultured; Chromatids; Cytarabine; DNA; DNA Damage; DNA Repair; Down Syndrome; Female; Fibroblasts; G1 Phase; G2 Phase; Humans; Light; Lymphocytes; Male; Ultraviolet Rays

1996
Paclitaxel-induced apoptosis in MCF-7 breast-cancer cells.
    International journal of cancer, 1997, Jan-17, Volume: 70, Issue:2

    Topics: Adenocarcinoma; Antineoplastic Agents; Antineoplastic Agents, Phytogenic; Apoptosis; Breast Neoplasms; Caffeine; Cell Cycle; Cisplatin; Cytarabine; DNA Damage; DNA Fragmentation; DNA, Neoplasm; Doxorubicin; Estrogens; Female; Humans; Neoplasms, Hormone-Dependent; Paclitaxel; Tumor Cells, Cultured

1997
Demonstration of congenital anomalies in the joints of the forelimbs and hindlimbs caused by several pharmacological agents.
    Anatomia, histologia, embryologia, 1996, Volume: 25, Issue:4

    Topics: Abnormalities, Drug-Induced; Animals; Anti-Inflammatory Agents, Non-Steroidal; Anticarcinogenic Agents; Antimetabolites, Antineoplastic; Caffeine; Central Nervous System Stimulants; Cytarabine; Diterpenes; Dose-Response Relationship, Drug; Female; Forelimb; Hindlimb; Joints; Male; Mice; Mice, Inbred BALB C; Pregnancy; Prenatal Exposure Delayed Effects; Retinyl Esters; Sodium Salicylate; Vitamin A

1996
Activation of an ataxia telangiectasia mutation-dependent intra-S-phase checkpoint by anti-tumour drugs in HL-60 and human lymphoblastoid cells.
    British journal of haematology, 2000, Volume: 110, Issue:4

    Topics: Antimetabolites; Antineoplastic Agents; Ataxia Telangiectasia Mutated Proteins; Bromodeoxyuridine; Caffeine; Cell Cycle Proteins; Cell Line, Transformed; Cytarabine; DNA-Binding Proteins; Doxorubicin; Etoposide; Flow Cytometry; Gene Expression; HL-60 Cells; Humans; Mutation; Phosphodiesterase Inhibitors; Protein Serine-Threonine Kinases; S Phase; Signal Transduction; Topoisomerase II Inhibitors; Tumor Suppressor Proteins

2000
Similar defects in DNA repair and replication in the pigmented xerodermoid and the xeroderma pigmentosum variants.
    Carcinogenesis, 1980, Volume: 1, Issue:8

    Topics: Adolescent; Adult; Antimetabolites; Caffeine; Cells, Cultured; Cytarabine; DNA Damage; DNA Repair; DNA Replication; Humans; Male; Pigmentation Disorders; Replication Origin; Time Factors; Ultraviolet Rays; Xeroderma Pigmentosum

1980
ATR-mediated checkpoint pathways regulate phosphorylation and activation of human Chk1.
    Molecular and cellular biology, 2001, Volume: 21, Issue:13

    Topics: Adenoviridae; Amino Acid Motifs; Antineoplastic Agents; Ataxia Telangiectasia Mutated Proteins; Caffeine; Cell Cycle; Cell Cycle Proteins; Cell Line; Checkpoint Kinase 1; Cisplatin; Cytarabine; DNA Damage; Enzyme Activation; Etoposide; Genes, Reporter; Humans; Hydroxyurea; Immunoblotting; Nucleic Acid Synthesis Inhibitors; Phosphodiesterase Inhibitors; Phosphoric Monoester Hydrolases; Phosphorylation; Phosphoserine; Protein Kinases; Protein Serine-Threonine Kinases; Recombinant Fusion Proteins

2001
Induction of DNA ligase I by 1-beta-D-arabinosylcytosine and aphidicolin in MiaPaCa human pancreatic cancer cells.
    Experimental cell research, 2002, Oct-15, Volume: 280, Issue:1

    Topics: Antimetabolites, Antineoplastic; Aphidicolin; Caffeine; Cell Count; Cell Division; Cell Line; Cell Survival; Cytarabine; DNA Ligase ATP; DNA Ligases; DNA Repair; DNA-Directed DNA Polymerase; DNA, Neoplasm; Dose-Response Relationship, Drug; Enzyme Inhibitors; Humans; Nucleic Acid Synthesis Inhibitors; Pancreatic Neoplasms; Phosphodiesterase Inhibitors; RNA, Messenger; Tumor Cells, Cultured

2002
Role of Chk1 and Chk2 in Ara-C-induced differentiation of human leukemia K562 cells.
    Genes to cells : devoted to molecular & cellular mechanisms, 2005, Volume: 10, Issue:2

    Topics: Antimetabolites, Antineoplastic; Ataxia Telangiectasia Mutated Proteins; Caffeine; Carbazoles; cdc25 Phosphatases; Cell Cycle Proteins; Cell Differentiation; Checkpoint Kinase 1; Checkpoint Kinase 2; Cytarabine; DNA-Binding Proteins; Erythrocytes; Humans; Indoles; Intracellular Signaling Peptides and Proteins; K562 Cells; Phosphorylation; Proteasome Endopeptidase Complex; Protein Kinases; Protein Serine-Threonine Kinases; RNA, Small Interfering; Tumor Suppressor Proteins

2005