cytarabine has been researched along with aphidicolin in 88 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 55 (62.50) | 18.7374 |
| 1990's | 27 (30.68) | 18.2507 |
| 2000's | 5 (5.68) | 29.6817 |
| 2010's | 1 (1.14) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Andrais, B; Mirzayans, R; Paterson, MC | 1 |
| Aranda-Anzaldo, A | 1 |
| Costa, JV; Marques, MI | 1 |
| Bianchi, V; Pontis, E; Reichard, P | 1 |
| Chung, HW; Morgan, WF; Phillips, JW; Preston, RJ; Winegar, RA | 1 |
| Collins, AR; Gedik, CM | 1 |
| Frankfurt, OS | 1 |
| Datta, R; Kharbanda, S; Kufe, D | 1 |
| Labanowska, J; Tolmach, LJ | 1 |
| Bag, J; Meadus, WJ | 1 |
| Meneghini, R; Ortega, JM; Schumacher, RI; Ventura, AM | 1 |
| Pfeifer, GP; Steigerwald, SD | 1 |
| Akiyama, Y; Kiriyama, Y; Kito, T; Kubota, M; Mikawa, H; Takimoto, T; Tanizawa, A | 1 |
| Ahnström, G | 1 |
| Akiyama, Y; Kitoh, T; Kubota, M; Mikawa, H; Takimoto, T; Tanizawa, A; Tsuruta, S | 1 |
| Iliakis, G; Okayasu, R; Pantelias, G; Seaner, R | 1 |
| Dahlberg, WK; Little, JB; Ueno, AM | 1 |
| Chitnis, MP; Deshpande, SS; Satyamoorthy, K | 1 |
| Denizeau, F; Jutras, D; Marion, M | 1 |
| Wawra, E | 1 |
| Collins, AR; Downes, CS; Johnson, RT; Mullinger, AM; Ord, MJ | 1 |
| Cleaver, JE; Karentz, D | 1 |
| Jones, PA; Liu, L; Nyce, J | 1 |
| Wainwright, LK; Wainwright, SD | 1 |
| Downes, CS; Elliott, GC | 1 |
| Collins, A | 1 |
| Moore, RC; Randall, C | 1 |
| Bishov, SD; Fram, RJ; Robichaud, N; Wilson, JM | 1 |
| Fram, RJ; Robichaud, NJ | 1 |
| Collins, AR; Downes, CS; Elliott, GC; Johnson, RT; Mullinger, AM; Rasko, I; Squires, S | 1 |
| Reidy, JA | 1 |
| Moore, RC; Randell, C | 1 |
| Bender, MA; Moore, RC; Randell, C | 1 |
| Leonard, JC; Leonard, RC; Thompson, KH | 1 |
| Berney, JJ; Francis, GE; Guimaraes, JE; Wing, MA | 2 |
| Griffin, JD; Kufe, DW; Spriggs, DR | 1 |
| Kufe, DW; Spriggs, DR | 1 |
| Mishra, NC; Vishwanatha, JK | 2 |
| Ishikura, H; Izumi, Y; Mochizuki, T; Okazaki, T; Sawada, H; Tashima, M; Uchino, H | 1 |
| Hyodo, M; Ito, N; Suzuki, K; Yamashita, M | 1 |
| Fram, RJ; Kufe, DW | 3 |
| Ayusawa, D; Iwata, K; Seno, T | 1 |
| Aoki, H; Maeno, K; Nishiyama, Y; Tsurumi, T | 1 |
| Cleaver, JE | 2 |
| Aizawa, S; Loeb, LA; Martin, GM | 1 |
| Clarkson, JM; Mitchell, DL | 1 |
| Bradley, MO; Taylor, VI | 1 |
| Okumoto, DS; Smith, CA | 1 |
| Baumbach, LL; Marashi, F; Plumb, M; Stein, G; Stein, J | 1 |
| Egan, E; Herrick, D; Kufe, DW; Munroe, D; Spriggs, D | 1 |
| Mariani, T; Rainaldi, G; Sessa, MR | 1 |
| Wist, E | 1 |
| Collins, AR; Johnson, RT; Squires, S | 1 |
| Crocombe, K; Mirzayans, R; Waters, R | 1 |
| Preston, RJ | 1 |
| Hanaoka, F; Kato, H; Yamada, K; Yamada, M | 2 |
| Ayurawa, D; Iwata, K; Seno, T | 1 |
| Charles, WC; Cleaver, JE | 1 |
| Griffin, J; Kufe, D; Major, P; Munroe, D | 1 |
| Bessho, R; Kataoka, A; Kubota, M; Kuwakado, K; Lin, YW; Okuda, A; Usami, I; Wakazono, Y | 1 |
| Bramson, J; Panasci, L | 1 |
| Fox, MH; Hang, H | 1 |
| Mishra, NC; Singleton, RW | 1 |
| Brinkman, W; Heaton, D; Mustafi, R; Schwartz, JL | 1 |
| Cubitt, S; Enns, L; Karimian, K; Mirzayans, R; Paterson, MC; Radatus, B | 1 |
| Plunkett, W; Xu, YZ | 1 |
| Smit, JA; Stark, JH | 1 |
| Dietrich, K; Mirzayans, R; Paterson, MC | 1 |
| Hamlin, JL; Levenson, V | 1 |
| Taddie, JA; Traktman, P | 1 |
| Gutierrez, C; Litvak, S; Rojas, C; Solari, A | 1 |
| Dubinina, LG | 1 |
| Antoccia, A; Chessa, L; Ricordy, R; Tanzarella, C | 1 |
| Geller, HM; Greene, LA; Morris, EJ; Park, DS; Shelanski, ML; Stefanis, L; Troy, CM | 1 |
| Armstrong, MJ; Bradt, CI; Galloway, SM; Greenwood, SK; Hill, RB; Hilliard, CA; Johnson, TE | 1 |
| Elgie, AW; Sargent, JM; Taylor, CG; Williamson, CJ | 1 |
| Elgie, AW; Lewandowicz, GM; Sargent, JM; Taylor, CG; Williamson, CJ | 1 |
| Doroshenko, N; Doroshenko, P; Sabanov, V | 1 |
| Lopez, BS; Saintigny, Y | 1 |
| Buzello, C; Nguyen, M; Sun, D; Urrabaz, R | 1 |
| Broekhuizen, AJ; Creutzig, U; Gibson, BE; Hubeek, I; Kaspers, GJ; Peters, GJ; Sargent, J | 1 |
| Capron, C; Emile, JF; Finzi, L; Goere, D; Kraemer, A; Legagneux, J; Malafosse, R; Nordlinger, B; Noullet, S; Penna, C | 1 |
2 review(s) available for cytarabine and aphidicolin
| Article | Year |
|---|---|
Cellular and clinical pharmacology of low-dose ara-C.
Topics: Adult; Aged; Aphidicolin; Bone Marrow; Cell Differentiation; Cell Division; Cell Line; Cytarabine; Diterpenes; DNA; DNA Replication; Dose-Response Relationship, Drug; Female; Hemoglobins; Humans; Karyotyping; Kinetics; Leukemia; Male; Middle Aged; Preleukemia | 1985 |
Biochemical and cellular pharmacology of cytosine arabinoside.
Topics: Animals; Aphidicolin; Arabinofuranosylcytosine Triphosphate; Binding, Competitive; Cell Line; Cell Survival; Centrifugation, Density Gradient; Cytarabine; Diterpenes; DNA; DNA Repair; DNA Replication; Fibroblasts; Granulocytes; Humans; Kinetics; Leukemia L1210; Leukemia, Myeloid, Acute; Nucleic Acid Synthesis Inhibitors; Templates, Genetic; Vidarabine | 1985 |
86 other study(ies) available for cytarabine and aphidicolin
| Article | Year |
|---|---|
Synergistic effect of aphidicolin and 1-beta-D-arabinofuranosylcytosine on the repair of gamma-ray-induced DNA damage in normal human fibroblasts.
Topics: Aphidicolin; Centrifugation, Density Gradient; Cobalt Radioisotopes; Cytarabine; DNA; DNA Damage; DNA Repair; Drug Synergism; Fibroblasts; Gamma Rays; Humans; Hydroxyurea; Radiation Dosage; Ultraviolet Rays | 1992 |
Evidence for an altered kinetics of DNA excision-repair in cells infected by herpes simplex virus type 1.
Topics: Animals; Aphidicolin; Chromosome Aberrations; Cytarabine; DNA Damage; DNA Repair; HeLa Cells; Humans; Kinetics; L Cells; Mice; Simplexvirus; Ultraviolet Rays | 1992 |
African swine fever virus-induced DNA polymerase is resistant to aphidicolin.
Topics: African Swine Fever Virus; Aphidicolin; Cytarabine; DNA-Directed DNA Polymerase; DNA, Viral; Drug Resistance, Microbial; Kinetics; Phosphonoacetic Acid | 1992 |
Dynamics of the dATP pool in cultured mammalian cells.
Topics: 3T3 Cells; Adenine; Animals; Aphidicolin; Cell Line; Cytarabine; Deoxyadenine Nucleotides; Deoxyadenosines; DNA; Hypoxanthine; Hypoxanthines; Kinetics; Mice; Pentostatin; Substrate Cycling; Thymine Nucleotides | 1992 |
Modulation of restriction enzyme-induced damage by chemicals that interfere with cellular responses to DNA damage: a cytogenetic and pulsed-field gel analysis.
Topics: Animals; Aphidicolin; Benzamides; Caffeine; Cytarabine; Deoxyribonucleases, Type II Site-Specific; Diterpenes; DNA Damage | 1991 |
The mode of action of 1-beta-D-arabinofuranosylcytosine in inhibiting DNA repair; new evidence using a sensitive assay for repair DNA synthesis and ligation in permeable cells.
Topics: Aphidicolin; Binding, Competitive; Cell Membrane Permeability; Cytarabine; Diterpenes; DNA; DNA Damage; DNA Repair; HeLa Cells; Humans; Hydroxyurea; Nucleic Acid Synthesis Inhibitors; Ultraviolet Rays | 1991 |
Inhibition of DNA repair and the enhancement of cytotoxicity of alkylating agents.
Topics: Alkylating Agents; Antineoplastic Agents; Aphidicolin; Cell Line; Cell Survival; Cisplatin; Cytarabine; Diterpenes; DNA Damage; DNA Repair; Female; Humans; Lung Neoplasms; Melphalan; Nucleic Acid Synthesis Inhibitors; Ovarian Neoplasms; Thiotepa | 1991 |
Regulation of c-jun gene expression in HL-60 leukemia cells by 1-beta-D-arabinofuranosylcytosine. Potential involvement of a protein kinase C dependent mechanism.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Aphidicolin; Cell Line; Cell Nucleus; Cycloheximide; Cytarabine; Dactinomycin; Diterpenes; DNA-Binding Proteins; Enzyme Activation; Gene Expression Regulation, Neoplastic; Humans; Isoquinolines; Kinetics; Leukemia, Promyelocytic, Acute; Piperazines; Protein Kinase C; Protein-Tyrosine Kinases; Proto-Oncogene Proteins c-jun; Proto-Oncogenes; RNA, Neoplasm; Sulfonamides; Transcription Factors; Transcription, Genetic | 1991 |
Kinetics of the development of accelerated cell-cycle transit resulting from inhibition of DNA replication in the previous cycle.
Topics: Antineoplastic Agents; Aphidicolin; Cell Cycle; Cytarabine; Diterpenes; DNA; DNA Polymerase II; DNA Replication; HeLa Cells; Humans; Hydroxyurea; Interphase; Mitosis; Thymidine | 1990 |
The effect of inhibitors of DNA synthesis on 40-kilodalton polypeptide translation in rat L6 myoblasts.
Topics: Animals; Aphidicolin; Cell Differentiation; Cell Division; Cells, Cultured; Cytarabine; Diterpenes; DNA Replication; Gene Expression Regulation; Muscles; Peptide Biosynthesis; Protein Biosynthesis; Rats; RNA, Messenger | 1990 |
Recovery of DNA synthesis from inhibition by ultraviolet light in mammalian cells.
Topics: Animals; Aphidicolin; Cells, Cultured; Cricetinae; Cricetulus; Cytarabine; Dactinomycin; Diterpenes; DNA; DNA Polymerase II; DNA Repair; Floxuridine; RNA; Ultraviolet Rays | 1987 |
Variable DNA methylation changes during differentiation of human melanoma cells.
Topics: Aphidicolin; Azacitidine; Cell Differentiation; Cell Division; Chromatography, High Pressure Liquid; Cytarabine; Decitabine; Diterpenes; DNA; DNA, Neoplasm; Humans; Hydroxyurea; Methylation; Monophenol Monooxygenase; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured | 1988 |
Synergistic effect of methotrexate and 1-beta-D-arabinofuranosylcytosine on the generation of DNA strand breaks in a human promyelocytic leukemia cell line.
Topics: Aphidicolin; Cell Line; Cytarabine; Diterpenes; DNA Damage; Drug Combinations; Drug Synergism; Humans; Hypoxanthine; Hypoxanthines; Leucovorin; Leukemia, Promyelocytic, Acute; Methotrexate; Phosphorylation; Thymidine | 1989 |
Inhibition of DNA strand break rejoining in ultraviolet-irradiated human cells: comparison of aphidicolin and cytosine arabinoside.
Topics: Aphidicolin; Cell Line; Cytarabine; Diterpenes; DNA; DNA Damage; DNA Repair; Humans; In Vitro Techniques; Time Factors; Ultraviolet Rays | 1989 |
Cell cycle related change of Ara-C transport in HL-60 cells after differentiation induction.
Topics: Aphidicolin; Biological Transport; Cell Cycle; Cell Differentiation; Cell Membrane; Cytarabine; Deoxycytidine Kinase; Diterpenes; Humans; Interphase; Leukemia, Promyelocytic, Acute; Mutation; Tretinoin; Tumor Cells, Cultured | 1989 |
Comparative studies on repair inhibition by araA, araC and aphidicolin of radiation induced DNA and chromosome damage in rodent cells: comparison with fixation of PLD.
Topics: Animals; Aphidicolin; Cell Line; Cell Survival; Chromosomes; Cricetinae; Cytarabine; Diterpenes; DNA; DNA Damage; DNA Repair; DNA Replication; Vidarabine | 1989 |
Differential response of human and rodent cell lines to chemical inhibition of the repair of potentially lethal damage.
Topics: Adenosine Diphosphate Ribose; Animals; Aphidicolin; Benzamides; Cell Line; Cricetinae; Cricetulus; Cytarabine; Diterpenes; DNA Polymerase II; DNA Repair; Fibroblasts; Humans; Hydroxyurea; Mice; Vidarabine | 1989 |
Differential effect of collaterally sensitive antimetabolites on P388 murine leukemia sensitive and resistant to adriamycin in vitro.
Topics: Animals; Antimetabolites, Antineoplastic; Aphidicolin; Cytarabine; Diterpenes; DNA Polymerase II; DNA, Neoplasm; Doxorubicin; Drug Resistance; Hydroxyurea; Inosine; Leukemia P388; Leukemia, Experimental; Mice; Ribonucleotide Reductases; RNA, Neoplasm; Tumor Cells, Cultured | 1989 |
The effects of putative DNA repair inhibitors on DNA adduct levels and unscheduled DNA synthesis in rat hepatocytes exposed to 2-acetylaminofluorene.
Topics: 2-Acetylaminofluorene; Animals; Aphidicolin; Cells, Cultured; Cytarabine; Dideoxynucleosides; Diterpenes; DNA Damage; DNA Repair; Hydroxyurea; In Vitro Techniques; Liver; Male; Nalidixic Acid; Nucleic Acid Synthesis Inhibitors; Rats; Topoisomerase I Inhibitors | 1989 |
Microinjected deoxynucleotides for the study of chemical inhibition of DNA synthesis.
Topics: Animals; Aphidicolin; Autoradiography; Cell Nucleus; Cells, Cultured; Cytarabine; Deoxyribonucleotides; Diterpenes; DNA Replication; Floxuridine; Hydroxyurea; Kinetics; Methotrexate; Trifluridine; Tritium | 1988 |
Novobiocin inhibition of DNA excision repair may occur through effects on mitochondrial structure and ATP metabolism, not on repair topoisomerases.
Topics: Adenosine Triphosphate; Aphidicolin; Chromosomes; Cytarabine; Diterpenes; DNA Repair; HeLa Cells; Humans; Hydroxyurea; Mitochondria; Novobiocin; Topoisomerase I Inhibitors | 1985 |
Excision repair in xeroderma pigmentosum group C but not group D is clustered in a small fraction of the total genome.
Topics: Aphidicolin; Benzamides; Cell Line; Chromosome Mapping; Cycloheximide; Cytarabine; Diterpenes; DNA; DNA Repair; Genetic Complementation Test; Humans; Molecular Weight; Novobiocin; Ultraviolet Rays; Xeroderma Pigmentosum | 1986 |
Variable effects of DNA-synthesis inhibitors upon DNA methylation in mammalian cells.
Topics: Animals; Aphidicolin; Base Sequence; Cell Line; Chromatography, High Pressure Liquid; Cricetinae; Cycloheximide; Cytarabine; Dactinomycin; Diterpenes; DNA; DNA Polymerase II; DNA Replication; Fibrosarcoma; Hydroxyurea; Methylation; Nalidixic Acid; Novobiocin | 1986 |
Effects of some inhibitors of DNA synthesis and repair upon the cycle of serotonin N-acetyltransferase activity in cultured chick pineal glands.
Topics: Acetyltransferases; Animals; Aphidicolin; Arylamine N-Acetyltransferase; Benzamides; Cells, Cultured; Chickens; Circadian Rhythm; Cytarabine; Darkness; Deoxyadenosines; Dideoxynucleosides; Diterpenes; DNA Repair; DNA Replication; Kinetics; Light; Pineal Gland; Thymidine | 1986 |
Qualitative differences between replicative and repair synthesis of DNA in normal and transformed mouse cells as measured by precursor discrimination.
Topics: Animals; Aphidicolin; Bromodeoxyuridine; Cell Line; Cell Transformation, Neoplastic; Chromosome Aberrations; Cytarabine; Deoxycytidine; Diterpenes; DNA; DNA Damage; DNA Polymerase II; DNA Repair; DNA Replication; Embryo, Mammalian; Mice; Substrate Specificity; Ultraviolet Rays | 1986 |
Estimates of the rate of ligation during excision repair of ultraviolet-damaged DNA in mammalian cells.
Topics: Adenosine Diphosphate Ribose; Animals; Aphidicolin; Benzamides; Cells, Cultured; Cricetinae; Cytarabine; Diterpenes; DNA; DNA Damage; DNA Repair; Humans; Hydroxyurea; Kinetics; Ultraviolet Rays | 1987 |
Different effects of 1-beta-D-arabinofuranosylcytosine and aphidicolin in S-phase cells--chromosome aberrations, cell-cycle delay and cytotoxicity.
Topics: Animals; Aphidicolin; Cell Cycle; Cell Line; Cell Survival; Chromosome Aberrations; Cytarabine; Diterpenes; DNA; DNA Replication; Drug Administration Schedule; Interphase; Macropodidae | 1987 |
Interactions of cis-diamminedichloroplatinum(II) with 1-beta-D-arabinofuranosylcytosine in LoVo colon carcinoma cells.
Topics: Aphidicolin; Carcinoma; Cell Line; Cell Survival; Cisplatin; Colonic Neoplasms; Cytarabine; Diterpenes; DNA Damage; DNA Repair; Humans | 1987 |
Potentiation of ara-C induced cytotoxicity by hydroxyurea in LoVo colon carcinoma cells.
Topics: Aphidicolin; Cell Line; Cell Survival; Colonic Neoplasms; Cytarabine; Diterpenes; DNA; Drug Resistance; Drug Synergism; Hydroxyurea | 1987 |
DNA repair under stress.
Topics: Aphidicolin; Cell Survival; Chromosomes; Cytarabine; Diterpenes; DNA; DNA Repair; DNA Replication; HeLa Cells; Humans; Hydroxyurea; Novobiocin; Ultraviolet Rays | 1987 |
Folate- and deoxyuridine-sensitive chromatid breakage may result from DNA repair during G2.
Topics: Aphidicolin; Chromosome Aberrations; Chromosome Fragility; Cytarabine; Deoxyuridine; Diterpenes; DNA Repair; Folic Acid; Humans; In Vitro Techniques; Interphase; Lymphocytes; Uracil | 1987 |
Synergism of 1-beta-D-arabinofuranosylcytosine with itself and aphidicolin.
Topics: Aphidicolin; Cell Cycle; Cell Line; Chromosome Aberrations; Cytarabine; Diterpenes; DNA Repair; Drug Administration Schedule; Drug Synergism; Mutation | 1988 |
An investigation using inhibition of G2 repair of the molecular basis of lesions which result in chromosomal aberrations.
Topics: Animals; Aphidicolin; Cells, Cultured; Chromosome Aberrations; Cytarabine; Diterpenes; DNA Damage; DNA Repair; Interphase; Sister Chromatid Exchange; X-Rays | 1988 |
Arabinofuranosyl nucleosides induce common fragile sites.
Topics: Aphidicolin; Chromosome Fragile Sites; Chromosome Fragility; Cytarabine; Diterpenes; Female; Humans; Male; Nucleic Acid Synthesis Inhibitors; Vidarabine | 1988 |
Synergistic interaction between differentiation inducers and DNA synthesis inhibitors: a new approach to differentiation induction in myelodysplasia and acute myeloid leukaemia.
Topics: Antineoplastic Combined Chemotherapy Protocols; Aphidicolin; Bone Marrow; Bone Marrow Diseases; Cell Differentiation; Cells, Cultured; Cytarabine; Diterpenes; DNA; Drug Synergism; Formamides; Humans; Leukemia, Myeloid, Acute; Mercaptopurine; Preleukemia; Syndrome; Tretinoin | 1985 |
Differentiation in myelodysplastic, myeloid leukaemic and normal haemopoietic cells: a new approach exploiting the synergistic interaction between differentiation inducers and DNA synthesis inhibitors.
Topics: Antineoplastic Agents; Aphidicolin; Bone Marrow; Bone Marrow Cells; Cell Differentiation; Cells, Cultured; Cytarabine; Diterpenes; DNA Replication; Formamides; Hematopoietic Stem Cells; Humans; Leukemia, Myeloid; Mercaptopurine; Myeloproliferative Disorders; Reference Values; Tretinoin | 1985 |
Chinese hamster ovary cell mutants resistant to DNA polymerase inhibitors. I. Isolation and biochemical genetic characterization.
Topics: Animals; Aphidicolin; Cell Division; Cell Line; Cricetinae; Cricetulus; Cytarabine; Diterpenes; DNA Polymerase II; Drug Resistance; Female; Kinetics; Mutation; Nucleic Acid Synthesis Inhibitors; Ovary; Vidarabine | 1985 |
Chinese hamster ovary cell mutants resistant to DNA polymerase inhibitors. II. Segregational analysis and DNA transfection of the aphr gene.
Topics: Animals; Aphidicolin; Cell Line; Cricetinae; Cricetulus; Cytarabine; Diterpenes; DNA; DNA Polymerase II; Drug Resistance; Female; Genes; Mutation; Nucleic Acid Synthesis Inhibitors; Ovary; Transfection; Vidarabine | 1985 |
Effect of antimetabolites and thymidine blockage on the induction of differentiation of HL-60 cells by retinoic acid or 1 alpha,25-dihydroxyvitamin D3.
Topics: Antibiotics, Antineoplastic; Aphidicolin; Calcitriol; Cell Differentiation; Cell Division; Cell Line; Cytarabine; Diterpenes; DNA Replication; Humans; Hydroxyurea; Kinetics; Leukemia, Myeloid, Acute; Tretinoin | 1985 |
An improved method for isolation of mutator mutants from mouse FM3A cells and their characterization.
Topics: Animals; Aphidicolin; Cell Line; Cell Separation; Cytarabine; Diterpenes; DNA Replication; Guanidines; Mammary Neoplasms, Experimental; Mice; Mutation; Nucleosides; Ouabain; Thioguanine; Tunicamycin | 1985 |
Inhibition of DNA excision repair and the repair of X-ray-induced DNA damage by cytosine arabinoside and hydroxyurea.
Topics: Aphidicolin; Cytarabine; Diterpenes; DNA; DNA Damage; DNA Repair; Hydroxyurea | 1985 |
Unusual sensitivity to bleomycin and joint resistance to 9-beta-D-arabinofuranosyladenine and 1-beta-D-arabinofuranosylcytosine of mouse FM3A cell mutants with altered ribonucleotide reductase and thymidylate synthase.
Topics: Animals; Antibiotics, Antineoplastic; Aphidicolin; Bleomycin; Cell Line; Cell Survival; Cytarabine; Diterpenes; Drug Resistance; Kinetics; Mammary Neoplasms, Experimental; Methyltransferases; Mice; Mice, Inbred C3H; Mutation; Ribonucleotide Reductases; Thymidylate Synthase; Vidarabine | 1983 |
Identification of DNA polymerase(s) involved in the repair of viral and cellular DNA in herpes simplex virus type 2-infected cells.
Topics: Aphidicolin; Cell Line; Cytarabine; Diterpenes; DNA; DNA Polymerase I; DNA Repair; DNA, Viral; Humans; Phosphonoacetic Acid; Simplexvirus | 1983 |
Structure of repaired sites in human DNA synthesized in the presence of inhibitors of DNA polymerases alpha and beta in human fibroblasts.
Topics: Aphidicolin; Cells, Cultured; Cytarabine; Dideoxynucleosides; Diterpenes; DNA Polymerase I; DNA Polymerase II; DNA Repair; DNA Replication; Fibroblasts; Humans; Kinetics; Nucleic Acid Synthesis Inhibitors; Skin; Thymidine | 1983 |
Mouse teratocarcinoma cells resistant to aphidicolin and arabinofuranosyl cytosine: isolation and initial characterization.
Topics: Animals; Aphidicolin; Cell Line; Cell Separation; Cytarabine; Diterpenes; Dose-Response Relationship, Drug; Drug Resistance; Methylnitronitrosoguanidine; Mice; Teratoma | 1983 |
The effect of various inhibitors of DNA synthesis on the repair of DNA photoproducts.
Topics: Animals; Aphidicolin; Cell Line; Cricetinae; Cricetulus; Cytarabine; Diterpenes; DNA; DNA Polymerase II; DNA Repair; DNA Replication; Female; Hydroxyurea; Kinetics; Nalidixic Acid; Novobiocin; Ovary; Ultraviolet Rays | 1983 |
Repair-induced DNA double strand breaks after ultraviolet-light and either aphidocolin or 1-beta-D-arabinofuranosylcytosine/hydroxyurea.
Topics: Aphidicolin; Cell Line; Cytarabine; Diterpenes; DNA; DNA Polymerase II; DNA Repair; Dose-Response Relationship, Radiation; Humans; Hydroxyurea; Kinetics; Lung; Ultraviolet Rays | 1983 |
Completion of excision repair patches in human cell preparations: identification of a probable mode of excision and resynthesis.
Topics: Aphidicolin; Cell Line; Cell Nucleus; Cytarabine; Dideoxynucleosides; Diterpenes; DNA Polymerase I; DNA Polymerase II; DNA Repair; DNA Replication; Fibroblasts; Humans; Thymidine; Ultraviolet Rays | 1984 |
Nature of DNA repair synthesis resistant to inhibitors of polymerase alpha in human cells.
Topics: Aphidicolin; Cell Division; Cells, Cultured; Cytarabine; Diterpenes; DNA Polymerase II; DNA Repair; Dose-Response Relationship, Radiation; Humans; Kinetics; Molecular Weight; Ultraviolet Rays | 1984 |
Inhibition of DNA replication coordinately reduces cellular levels of core and H1 histone mRNAs: requirement for protein synthesis.
Topics: Aphidicolin; Cycloheximide; Cytarabine; Dactinomycin; Diterpenes; DNA Polymerase II; DNA Replication; HeLa Cells; Histones; Humans; Hydroxyurea; Kinetics; Protein Biosynthesis; RNA, Messenger; Transcription, Genetic | 1984 |
Effects of 1-beta-D-arabinofuranosylcytosine incorporation on eukaryotic DNA template function.
Topics: Animals; Aphidicolin; Cell Survival; Cytarabine; Diterpenes; DNA Replication; DNA, Neoplasm; Kinetics; Leukemia L1210; Mice; Templates, Genetic | 1984 |
Inhibitors of DNA synthesis induce sister chromatid exchanges at the early S phase of the cell cycle.
Topics: Animals; Aphidicolin; Cell Line; Cricetinae; Cricetulus; Crossing Over, Genetic; Cytarabine; Diterpenes; DNA; DNA Polymerase II; DNA Replication; Interphase; Sister Chromatid Exchange; Thymidine | 1984 |
The effect of inhibitors of DNA synthesis on DNA repair.
Topics: Alkylating Agents; Animals; Aphidicolin; Cytarabine; Diterpenes; DNA Polymerase II; DNA Repair; DNA Replication; DNA, Neoplasm; Hydroxyurea; Kinetics; Leukemia L1210; Mice; Ultraviolet Rays | 1984 |
Effects of araC and aphidicolin on DNA chain elongation rate in HeLa S3 cells.
Topics: Anti-Bacterial Agents; Aphidicolin; Cytarabine; Diterpenes; DNA Replication; DNA, Neoplasm; HeLa Cells; Humans; Molecular Weight | 1980 |
Inhibitors of repair DNA synthesis.
Topics: Antibiotics, Antineoplastic; Aphidicolin; Cell Line; Cytarabine; Diterpenes; DNA Repair; DNA Replication; Dose-Response Relationship, Drug; Dose-Response Relationship, Radiation; Fibroblasts; Humans; Hydroxyurea; Kinetics; Novobiocin; Ultraviolet Rays | 1982 |
The inhibition of DNA repair by aphidicolin or cytosine arabinoside in X-irradiated normal and xeroderma pigmentosum fibroblasts.
Topics: Aphidicolin; Cells, Cultured; Cytarabine; Diterpenes; DNA; DNA Polymerase II; DNA Repair; Fibroblasts; Humans; Xeroderma Pigmentosum | 1982 |
DNA strand breaks caused by inhibitors of DNA synthesis: 1-beta-D-arabinofuranosylcytosine and aphidicolin.
Topics: Animals; Aphidicolin; Cytarabine; Diterpenes; DNA Polymerase II; DNA Replication; Kinetics; Leukemia L1210; Mice; Nucleic Acid Synthesis Inhibitors | 1982 |
The use of inhibitors of DNA-repair in the study of the mechanisms of induction of chromosome aberrations.
Topics: Aphidicolin; Cell Cycle; Chromosome Aberrations; Cytarabine; Diterpenes; DNA Repair; Humans; In Vitro Techniques; Lymphocytes | 1982 |
Unscheduled DNA synthesis induced by N-methyl-N'-nitro-N-nitrosoguanidine in Hela cells.
Topics: Aphidicolin; Cytarabine; Dideoxynucleotides; Diterpenes; DNA; DNA Polymerase II; HeLa Cells; Humans; Hydroxyurea; Methylnitronitrosoguanidine; Nucleic Acid Synthesis Inhibitors; Thymine Nucleotides | 1982 |
Increased level of ribonucleotide reductase and associated resistance to aphidicolin in mouse FM3A cell mutants selected for simultaneous resistance to 9-beta-D-arabinofuranosyladenine and 1-beta-D-arabinofuranosylcytosine.
Topics: Animals; Aphidicolin; Cells, Cultured; Cytarabine; Diterpenes; DNA Polymerase II; Drug Resistance; Hydroxyurea; Mice; Mutation; Nucleic Acid Synthesis Inhibitors; Phenotype; Ribonucleotide Reductases; Thymidine; Vidarabine | 1982 |
Enhancement of ultraviolet-induced unscheduled DNA synthesis in HeLa cell lysate by aphidicolin in vivo.
Topics: Aphidicolin; Cytarabine; Diterpenes; DNA Polymerase II; DNA Replication; HeLa Cells; Humans; Hydroxyurea; Kinetics; Nucleic Acid Synthesis Inhibitors; Ultraviolet Rays | 1982 |
Comparison of nucleoid and alkaline sucrose gradients in the analysis of inhibitors of DNA repair in human fibroblasts.
Topics: Aphidicolin; Benzamides; Cell Line; Cytarabine; Dideoxynucleosides; Diterpenes; DNA Polymerase I; DNA Polymerase II; DNA Repair; DNA Replication; DNA, Single-Stranded; Embryology; Fibroblasts; Humans; Hydroxyurea; Molecular Weight; Nucleic Acid Synthesis Inhibitors; Skin; Thymidine; Ultraviolet Rays | 1982 |
Induction of differentiation of human myeloid leukemia cells by inhibitors of DNA synthesis.
Topics: Aphidicolin; Cell Line; Cell Transformation, Neoplastic; Clone Cells; Cytarabine; Depression, Chemical; Diterpenes; DNA; DNA-Directed DNA Polymerase; Humans; Leukemia, Myeloid, Acute; Nucleosides | 1982 |
Augmentation by aphidicolin of 1-beta-D-arabinofuranosylcytosine-induced c-jun and NF-kappa B activation in a human myeloid leukemia cell line: correlation with apoptosis.
Topics: Antimetabolites, Antineoplastic; Aphidicolin; Apoptosis; Base Sequence; Cytarabine; DNA Damage; DNA Polymerase II; Drug Synergism; Enzyme Inhibitors; Gene Expression Regulation, Neoplastic; Genes, jun; Genes, myc; Humans; Molecular Sequence Data; NF-kappa B; Oligodeoxyribonucleotides; Proto-Oncogene Proteins c-jun; RNA, Messenger; Tumor Cells, Cultured | 1995 |
Potentiation of chlorambucil toxicity in B-CLL lymphocytes using the DNA synthesis inhibitors aphidicolin and 1-beta-D-arabinofuranosylcytosine.
Topics: Aphidicolin; Chlorambucil; Cytarabine; DNA Replication; Drug Resistance; Drug Synergism; Humans; Leukemia, Lymphocytic, Chronic, B-Cell; Lymphocytes | 1995 |
Expression of hsp70 induced in CHO cells by 45.0 degrees C hyperthermia is cell cycle associated and DNA synthesis dependent.
Topics: Animals; Aphidicolin; Cell Cycle; CHO Cells; Cricetinae; Cricetulus; Cytarabine; DNA; Flow Cytometry; Hot Temperature; HSP70 Heat-Shock Proteins | 1995 |
Genetic evidence that aphidicolin inhibits in vivo DNA synthesis in Chinese hamster ovary cells.
Topics: Animals; Aphidicolin; CHO Cells; Cricetinae; Cytarabine; Deoxyguanosine; Diphosphonates; DNA; DNA Polymerase II; DNA Replication | 1995 |
Enhancement of X-ray toxicity in squamous cell carcinoma cell lines by DNA polymerase inhibitors.
Topics: Aphidicolin; Carcinoma, Squamous Cell; Cell Survival; Cytarabine; DNA Repair; DNA Replication; DNA, Neoplasm; Humans; In Vitro Techniques; Nucleic Acid Synthesis Inhibitors; Tumor Cells, Cultured; Vidarabine; X-Rays | 1994 |
Effect of DNA polymerase inhibitors on repair of gamma ray-induced DNA damage in proliferating (intact versus permeable) human fibroblasts: evidence for differences in the modes of action of aphidicolin and 1-beta-D-arabinofuranosylcytosine.
Topics: Aphidicolin; Arabinofuranosylcytosine Triphosphate; Cells, Cultured; Child; Cytarabine; DNA Repair; Drug Combinations; Fibroblasts; Humans; Nucleic Acid Synthesis Inhibitors; Saponins | 1994 |
Regulation of thymidine kinase and thymidylate synthase in intact human lymphoblast CCRF-CEM cells.
Topics: Aphidicolin; Carbon Radioisotopes; Cell Cycle; Cytarabine; Deoxycytidine; Deoxyuridine; DNA Replication; DNA, Neoplasm; Hydroxyurea; Kinetics; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Thymidine Kinase; Thymidylate Synthase; Time Factors; Tritium; Tumor Cells, Cultured | 1993 |
Inhibiting the repair of DNA damage induced by gamma irradiation in rat thymocytes.
Topics: Animals; Antineoplastic Agents; Aphidicolin; Benzamides; Cytarabine; DNA Damage; DNA Repair; Doxorubicin; Flavonoids; Gamma Rays; Kinetics; Naphthoquinones; Novobiocin; Radiation-Sensitizing Agents; Rats; Rats, Sprague-Dawley; T-Lymphocytes; Time Factors; Vidarabine | 1994 |
Aphidicolin and 1-beta-D-arabinofuranosylcytosine strongly inhibit transcriptionally active DNA repair in normal human fibroblasts.
Topics: 4-Nitroquinoline-1-oxide; Aphidicolin; Cell Line; Cytarabine; DNA Repair; Fibroblasts; Genes, myc; Humans; Mutagens; Transcription, Genetic; Ultraviolet Rays | 1993 |
A general protocol for evaluating the specific effects of DNA replication inhibitors.
Topics: Animals; Antifungal Agents; Aphidicolin; Cell Cycle; CHO Cells; Ciclopirox; Cricetinae; Cytarabine; DNA Replication; Electrophoresis, Gel, Two-Dimensional; Flow Cytometry; Genetic Techniques; Hydroxyurea; Mimosine; Pyridones; Replicon; Tetrahydrofolate Dehydrogenase | 1993 |
Genetic characterization of the vaccinia virus DNA polymerase: cytosine arabinoside resistance requires a variable lesion conferring phosphonoacetate resistance in conjunction with an invariant mutation localized to the 3'-5' exonuclease domain.
Topics: Animals; Aphidicolin; Base Sequence; Cell Line; Chlorocebus aethiops; Cytarabine; DNA-Directed DNA Polymerase; Drug Resistance; Exonucleases; In Vitro Techniques; L Cells; Mice; Molecular Sequence Data; Mutation; Nucleic Acid Synthesis Inhibitors; Oligodeoxyribonucleotides; Phosphonoacetic Acid; Restriction Mapping; Sequence Alignment; Species Specificity; Structure-Activity Relationship; Vaccinia virus; Virus Replication | 1993 |
Nuclear and kinetoplast DNA synthesis in Trypanosoma cruzi, autoradiographical study with DNA polymerase inhibitors.
Topics: Animals; Aphidicolin; Autoradiography; Cytarabine; Dideoxynucleosides; DNA, Circular; DNA, Kinetoplast; DNA, Protozoan; Nucleic Acid Synthesis Inhibitors; Trypanosoma cruzi | 1993 |
[The effect of inhibitors on induced mutagenesis].
Topics: Aphidicolin; Caffeine; Cell Line; Cytarabine; DNA Replication; G1 Phase; G2 Phase; Hydroxyurea; Mitomycin; Mutagenesis; Seeds | 1993 |
Modulation of radiation-induced chromosomal damage by inhibitors of DNA repair and flow cytometric analysis in ataxia telangiectasia cells with 'intermediate radiosensitivity'.
Topics: Aphidicolin; Ataxia Telangiectasia; Cell Cycle; Cells, Cultured; Chromosome Aberrations; Chromosomes, Human; Cytarabine; Dimethyl Sulfoxide; DNA Damage; DNA Repair; Flow Cytometry; G1 Phase; G2 Phase; Humans; Hydroxyurea; Lymphocytes; Nucleic Acid Synthesis Inhibitors; Radiation Tolerance; S Phase; Time Factors; X-Rays | 1995 |
Multiple pathways of neuronal death induced by DNA-damaging agents, NGF deprivation, and oxidative stress.
Topics: Animals; Antimetabolites, Antineoplastic; Aphidicolin; Apoptosis; Aspartic Acid; Cell Division; Cell Survival; Cyclin-Dependent Kinases; Cysteine Endopeptidases; Cytarabine; DNA Damage; Enzyme Inhibitors; Flavonoids; Humans; Kinetin; Nerve Growth Factors; Neurons; Oxidative Stress; PC12 Cells; Piperidines; Purines; Rats; Rats, Sprague-Dawley; S Phase; Superior Cervical Ganglion; Superoxide Dismutase; Ultraviolet Rays | 1998 |
Fewer chromosome aberrations and earlier apoptosis induced by DNA synthesis inhibitors, a topoisomerase II inhibitor or alkylating agents in human cells with normal compared with mutant p53.
Topics: Alkylating Agents; Antineoplastic Agents; Aphidicolin; Apoptosis; B-Lymphocytes; Cell Division; Cell Line; Chromosome Aberrations; Cytarabine; DNA Replication; Etoposide; Humans; Hydroxyurea; Methotrexate; Mutagenesis; Nucleic Acid Synthesis Inhibitors; Radiation, Ionizing; Topoisomerase II Inhibitors; Tumor Suppressor Protein p53 | 1998 |
Aphidicolin markedly increases the in vitro sensitivity to ara-C of blast cells from patients with AML.
Topics: Antibiotics, Antineoplastic; Antimetabolites, Antineoplastic; Antineoplastic Agents; Aphidicolin; Blast Crisis; Bone Marrow Cells; Cell Survival; Cytarabine; Drug Screening Assays, Antitumor; Drug Synergism; Etoposide; Humans; Leukemia, Myeloid, Acute; Tumor Cells, Cultured | 1999 |
Circumvention of ara-C resistance by aphidicolin in blast cells from patients with AML.
Topics: Antimetabolites, Antineoplastic; Aphidicolin; Cell Survival; Cytarabine; DNA; Drug Resistance; Drug Screening Assays, Antitumor; Enzyme Inhibitors; Fetal Blood; Formazans; Humans; Lethal Dose 50; Leukemia, Myeloid, Acute; Tetrazolium Salts; Tumor Cells, Cultured | 2001 |
Cell cycle-related changes in regulatory volume decrease and volume-sensitive chloride conductance in mouse fibroblasts.
Topics: Animals; Aphidicolin; Cell Cycle; Cell Division; Cell Line; Cell Size; Chlorides; Culture Media, Serum-Free; Cytarabine; Electric Conductivity; Enzyme Inhibitors; Fibroblasts; Hydroxyurea; Ion Transport; Lovastatin; Mice; Mimosine; Osmotic Pressure; Paclitaxel; Patch-Clamp Techniques | 2001 |
Homologous recombination induced by replication inhibition, is stimulated by expression of mutant p53.
Topics: Animals; Aphidicolin; Cell Cycle; Cell Line; Ciclopirox; Cytarabine; DNA Replication; Gene Expression; Genes, p53; Hydroxyurea; Mice; Mimosine; Mutation; Pyridones; Recombination, Genetic; Tumor Suppressor Protein p53 | 2002 |
Induction of DNA ligase I by 1-beta-D-arabinosylcytosine and aphidicolin in MiaPaCa human pancreatic cancer cells.
Topics: Antimetabolites, Antineoplastic; Aphidicolin; Caffeine; Cell Count; Cell Division; Cell Line; Cell Survival; Cytarabine; DNA Ligase ATP; DNA Ligases; DNA Repair; DNA-Directed DNA Polymerase; DNA, Neoplasm; Dose-Response Relationship, Drug; Enzyme Inhibitors; Humans; Nucleic Acid Synthesis Inhibitors; Pancreatic Neoplasms; Phosphodiesterase Inhibitors; RNA, Messenger; Tumor Cells, Cultured | 2002 |
Potentiation of in vitro ara-C cytotoxicity by ribonucleotide reductase inhibitors, cyclin-dependent kinase modulators and the DNA repair inhibitor aphidicolin in paediatric acute myeloid leukaemia.
Topics: Antimetabolites, Antineoplastic; Aphidicolin; Azacitidine; Child; Cyclin-Dependent Kinases; Cytarabine; Decitabine; Drug Screening Assays, Antitumor; Drug Synergism; Humans; Leukemia, Myeloid, Acute; Leukocytes, Mononuclear; Nucleic Acid Synthesis Inhibitors; Ribonucleotide Reductases | 2005 |
Improved retroviral suicide gene transfer in colon cancer cell lines after cell synchronization with methotrexate.
Topics: Animals; Antimetabolites, Antineoplastic; Antiviral Agents; Aphidicolin; Apoptosis; Cell Culture Techniques; Cell Cycle; Colonic Neoplasms; Cytarabine; Flow Cytometry; Ganciclovir; Gene Transfer Techniques; Genetic Therapy; Genetic Vectors; Humans; Methotrexate; Mice; Retroviridae; Simplexvirus; Thymidine Kinase; Tumor Cells, Cultured | 2011 |