cytarabine has been researched along with acetylcysteine in 17 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 2 (11.76) | 18.7374 |
| 1990's | 4 (23.53) | 18.2507 |
| 2000's | 6 (35.29) | 29.6817 |
| 2010's | 5 (29.41) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Benz, RD; Contrera, JF; Kruhlak, NL; Matthews, EJ; Weaver, JL | 1 |
| Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A | 1 |
| Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K | 1 |
| Huang, HS; Jiménez, JJ; Yunis, AA | 1 |
| Czarnomska, A; Czyzewska-Szafran, H; Danysz, A; Jastrzebski, Z | 1 |
| Kline, I | 1 |
| Hu, ZB; Li, M; McCulloch, EA; Minden, MD; Miyamoto, N; Yang, GS | 1 |
| Bessho, R; Hirota, H; Kawai, M; Kubota, M; Kuwakado, K; Lin, YW; Matsubara, K; Nishikomori, R; Okuda, A; Wakazono, Y | 1 |
| Fukuchi, K; Gomi, K; Nakamaki, T; Tomoyasu, S; Tsuruoka, N | 1 |
| Cheng, KY; Geller, HM; Goldsmith, NK; Grandison, L; Morris, EJ; Romero, AA; Zhang, AL | 1 |
| Ethiraj, KS; Hakimelahi, GH; Hakimelahi, S; Moosavi-Movahedi, AA; Pasdar, M; Sambaiah, T; Zhu, JL | 1 |
| Anastasopoulos, D; Kitraki, E; Kittas, C; Koros, C; Papalexi, E | 1 |
| Patel, R; Studzinski, GP; Wang, X | 1 |
| Kitraki, E; Koros, C | 1 |
| Braunagel, D; Dransfeld, CL; Ehninger, G; Kramer, M; Mahlknecht, U; Schaich, M | 1 |
| Liu, K; Lu, W; Wang, W; Zhang, Y | 1 |
| Acer, S; Balci, YI; Bozkurt, K; Kucukatay, V; Polat, A; Sarbay, H; Yagci, R | 1 |
1 review(s) available for cytarabine and acetylcysteine
| Article | Year |
|---|---|
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk | 2016 |
1 trial(s) available for cytarabine and acetylcysteine
| Article | Year |
|---|---|
The T_T genotype within the NME1 promoter single nucleotide polymorphism -835 C/T is associated with an increased risk of cytarabine induced neurotoxicity in patients with acute myeloid leukemia.
Topics: Acetylcysteine; Adolescent; Adult; Aged; Apoptosis; Cytarabine; Female; Genotype; Humans; Leukemia, Myeloid, Acute; Male; Middle Aged; Neurons; Neurotoxicity Syndromes; NM23 Nucleoside Diphosphate Kinases; Polymorphism, Single Nucleotide; Promoter Regions, Genetic; Retrospective Studies; Survival Rate; Young Adult | 2012 |
15 other study(ies) available for cytarabine and acetylcysteine
| Article | Year |
|---|---|
Assessment of the health effects of chemicals in humans: II. Construction of an adverse effects database for QSAR modeling.
Topics: Adverse Drug Reaction Reporting Systems; Artificial Intelligence; Computers; Databases, Factual; Drug Prescriptions; Drug-Related Side Effects and Adverse Reactions; Endpoint Determination; Models, Molecular; Quantitative Structure-Activity Relationship; Software; United States; United States Food and Drug Administration | 2004 |
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship | 2010 |
Treatment with ImuVert/N-acetylcysteine protects rats from cyclophosphamide/cytarabine-induced alopecia.
Topics: Acetylcysteine; Administration, Topical; Alopecia; Animals; Antineoplastic Combined Chemotherapy Protocols; Biological Products; Cyclophosphamide; Cytarabine; Immunologic Factors; Injections, Intraperitoneal; Injections, Subcutaneous; Random Allocation; Rats; Rats, Inbred F344; Rats, Inbred Strains | 1992 |
The effect of sodium-2-mercaptoethane-sulphonate, N-acetylcysteine and cysteine on the uptake of cytosine arabinoside by normal and neoplastic thymus cells of mice.
Topics: Acetylcysteine; Animals; Cells, Cultured; Cysteine; Cytarabine; Female; Male; Mercaptoethanol; Mesna; Mice; Thymus Gland; Thymus Neoplasms; Tumor Cells, Cultured | 1988 |
Potentially useful combinations of chemotherapy detected in mouse tumor systems.
Topics: Acetylcysteine; Animals; Antineoplastic Agents; Azauridine; Bleomycin; Camptothecin; Cyclic P-Oxides; Cyclophosphamide; Cytarabine; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Synergism; Drug Therapy, Combination; Ethylamines; Fluorouracil; Imidazoles; Leukemia L1210; Lung Neoplasms; Methotrexate; Mice; Neoplasms, Experimental; Oxazines; Piperazines; Procarbazine; Propane; Triazenes | 1974 |
Mechanism of cytosine arabinoside toxicity to the blast cells of acute myeloblastic leukemia: involvement of free radicals.
Topics: Acetylcysteine; Antioxidants; Base Sequence; Blotting, Northern; Cytarabine; Down-Regulation; Drug Interactions; Drug Screening Assays, Antitumor; Free Radicals; Gene Expression Regulation, Leukemic; Humans; Hydrocortisone; Hydrogen Peroxide; Leukemia, Myeloid, Acute; Lymphocyte Activation; Lymphocytes; Molecular Sequence Data; Polymerase Chain Reaction; Proto-Oncogene Mas; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-bcl-2; Transcription, Genetic; Tretinoin; Tumor Cells, Cultured | 1995 |
Pyrrolidine dithiocarbamate, a potent inhibitor of nuclear factor kappa B (NF-kappa B) activation, prevents apoptosis in human promyelocytic leukemia HL-60 cells and thymocytes.
Topics: Acetylcysteine; Apoptosis; Base Sequence; Cytarabine; Endonucleases; Etoposide; Humans; Leukemia, Promyelocytic, Acute; Molecular Sequence Data; NF-kappa B; Oligodeoxyribonucleotides; Phenanthrolines; Pyrrolidines; T-Lymphocytes; Thiocarbamates; Thymus Gland; Tumor Cells, Cultured | 1994 |
DNA damage induces p21 protein expression by inhibiting ubiquitination in ML-1 cells.
Topics: Acetylcysteine; Cell Nucleus; Cyclin-Dependent Kinase Inhibitor p21; Cyclins; Cysteine Proteinase Inhibitors; Cytarabine; Deferoxamine; DNA Damage; Etoposide; Gene Expression Regulation; Hydroxyurea; Polyribosomes; RNA, Messenger; Tumor Cells, Cultured; Ubiquitins | 1998 |
Oxidative stress mediates neuronal DNA damage and apoptosis in response to cytosine arabinoside.
Topics: Acetylcysteine; Animals; Apoptosis; Biological Transport; Cell Survival; Cells, Cultured; Cerebral Cortex; Cytarabine; Dipyridamole; DNA Damage; Embryo, Mammalian; Free Radical Scavengers; Kinetics; Models, Neurological; Neurons; Oxidative Stress; Rats; Uric Acid; Vitamin E | 2001 |
Reactions of purines-containing butenolides with L-cysteine or N-acetyl-L-cysteine as model biological nucleophiles: a potent mechanism-based inhibitor of ribonucleotide reductase caused apoptosis in breast carcinoma MCF7 cells.
Topics: 4-Butyrolactone; Acetylcysteine; Animals; Antineoplastic Agents; Apoptosis; Cell Division; Cell Line; Cysteine; Cytarabine; Dose-Response Relationship, Drug; Escherichia coli; Fibroblasts; Furans; Humans; Mice; Molecular Structure; Purines; Ribonucleotide Reductases; Sulfhydryl Compounds; Tumor Cells, Cultured | 2002 |
Effects of AraC treatment on motor coordination and cerebellar cytoarchitecture in the adult rat. A possible protective role of NAC.
Topics: Acetylcysteine; Animals; Antimetabolites, Antineoplastic; Calcium; Cerebellum; Cognition; Cytarabine; Cytoskeleton; Dose-Response Relationship, Drug; Immunohistochemistry; Male; Maze Learning; Mice; Neurofilament Proteins; Neuroprotective Agents; Postural Balance; Psychomotor Performance; Rats; Rats, Wistar; Space Perception; Walking | 2007 |
hKSR-2, a vitamin D-regulated gene, inhibits apoptosis in arabinocytosine-treated HL60 leukemia cells.
Topics: Acetylcysteine; Adaptor Proteins, Signal Transducing; Antioxidants; Apoptosis; Cytarabine; Gene Expression Regulation, Neoplastic; HL-60 Cells; Humans; Myeloid Cell Leukemia Sequence 1 Protein; Necrosis; Oligonucleotides, Antisense; Proto-Oncogene Proteins c-bcl-2; RNA, Messenger; RNA, Small Interfering; Vitamin D | 2008 |
Neurofilament isoform alterations in the rat cerebellum following cytosine arabinoside administration.
Topics: Acetylcysteine; Analysis of Variance; Animals; Antimetabolites, Antineoplastic; Antioxidants; Blotting, Western; Cerebellum; Cytarabine; Immunohistochemistry; Isomerism; Male; Neurofilament Proteins; Rats; Rats, Wistar | 2009 |
Mitochondrial reactive oxygen species regulate adipocyte differentiation of mesenchymal stem cells in hematopoietic stress induced by arabinosylcytosine.
Topics: Acetylcysteine; Adipocytes; Adipogenesis; Animals; Antioxidants; Cytarabine; Hematopoiesis; Humans; Male; Mesenchymal Stem Cells; Mice; Mice, Inbred C57BL; Mitochondria; Organophosphorus Compounds; Oxidative Stress; Piperidines; Reactive Oxygen Species | 2015 |
N-acetylcysteine supplementation reduces oxidative stress for cytosine arabinoside in rat model.
Topics: Acetylcysteine; Animals; Antioxidants; Conjunctiva; Cornea; Cytarabine; Dietary Supplements; Disease Models, Animal; Free Radical Scavengers; Immunosuppressive Agents; Oxidative Stress; Rats; Rats, Wistar | 2017 |