cytarabine has been researched along with 2'-deoxycytidine 5'-triphosphate in 43 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 20 (46.51) | 18.7374 |
| 1990's | 17 (39.53) | 18.2507 |
| 2000's | 6 (13.95) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Sasvári-Székely, M; Spasokukotskaja, T; Staub, M; Taljanidisz, J | 1 |
| Arentsen-Honders, MW; Colly, LP; Kester, MG; Richel, DJ; ter Riet, PM; Willemze, R | 1 |
| Allegra, CJ; Grem, JL | 2 |
| Chubb, S; Grindey, GB; Hertel, LW; Huang, P; Plunkett, W | 1 |
| Higashigawa, M; Hori, H; Kawasaki, H; Kuwabara, H; Ohkubo, T; Sakurai, M | 1 |
| Arlin, Z; Bhalla, K; Birkhofer, M; Graham, G; Grant, S; Lutzky, J; Safah, H | 1 |
| Bouffard, DY; Marie, JP; Marquet, J; Momparler, LF; Momparler, RL; Zittoun, J; Zittoun, R | 1 |
| Bhalla, K; Grant, S; McCrady, C | 1 |
| Chiba, P; Eher, R; Knapp, W; Köller, U; Kraupp, M; Salamon, J; Szekeres, T; Tihan, T | 1 |
| Akiyama, Y; Kubota, M; Mikawa, H; Takimoto, T; Tanizawa, A | 1 |
| Akiyama, Y; Kiriyama, Y; Kitoh, T; Kubota, M; Mikawa, H; Takimoto, T; Tanizawa, A | 1 |
| Higashigawa, M; Kamiya, H; Kawasaki, H; Ohkubo, T; Sakurai, M | 1 |
| Heinemann, V; Plunkett, W | 1 |
| David, JC; Maniey, D; Marquet, J; Zittoun, J; Zittoun, R | 1 |
| Antoni, F; Sasvári-Székely, M; Spasokukotskaja, T; Staub, M; Szyfter, K | 1 |
| Arlin, Z; Bhalla, K; Birkhofer, M; Graham, G; Grant, S; Lutzky, J | 1 |
| Joneckis, CC; Ross, DD; Song, TH; Wu, RK | 1 |
| Kufe, D; Matsukage, A; Ohno, T; Ohno, Y; Spriggs, D | 1 |
| Liliemark, JO; Plunkett, W | 1 |
| Aizawa, S; Loeb, LA; Martin, GM; Ohashi, M | 1 |
| van der Weyden, MB; Wiley, JS; Young, GJ; Young, I | 1 |
| Gonçalves, O; Meuth, M; Trudel, M | 1 |
| Dunn, WC; Regan, JD; Snyder, RD | 1 |
| Cohen, A; Ullman, B | 1 |
| Danhauser, LL; Rustum, YM | 1 |
| Creaven, P; Marquet, J; Rustum, Y; Zittoun, J; Zittoun, R | 1 |
| Hirota, H; Kamiya, H; Kawasaki, H; Komada, M; Nobori, T; Okubo, T; Sako, T; Sakurai, M; Shimizu, N | 1 |
| Bowman, WP; Danks, MK; Look, AT; Ochs, J; Rivera, G; Sinkule, JA | 1 |
| Danks, MK | 1 |
| Cuddy, DP; Ross, DD | 1 |
| Du, M; Gandhi, V; Kantarjian, HM; Plunkett, W | 1 |
| Tanaka, M | 1 |
| Buck, SA; Gurney, JG; Matherly, LH; Ravindranath, Y; Stout, ML; Taub, JW | 1 |
| Cohen, JD; Katz, TB; Marcel, PD; Strock, DJ; Teik, JE | 1 |
| Heinemann, V; Issels, RD; Schulz, L; Wilmanns, W | 1 |
| Ravindranath, Y; Taub, JW | 1 |
| Parker, WB; Rose, LM; Secrist, JA; Shaddix, SC; Shewach, DS; Tiwari, KN; Waud, WR | 1 |
| Azuma, A; Huang, P; Matsuda, A; Plunkett, W | 1 |
| Albertioni, F; Chandra, J; Eriksson, S; Knaust, E; Liliemark, E; Lotfi, K; Månsson, E; Spasokoukotskaja, T; Wang, Y; Xu, D | 1 |
| Leen, R; van Gennip, AH; van Kuilenburg, AB; Verschuur, AC; Voûte, PA | 1 |
| Bauer, W; Fritzer-Szekeres, M; Höchtl, T; Horvath, Z; Karl, D; Saiko, P; Szekeres, T | 1 |
| Hori, H; Kawai, Y; Ueda, T; Yoshio, N | 1 |
2 review(s) available for cytarabine and 2'-deoxycytidine 5'-triphosphate
| Article | Year |
|---|---|
The genetic consequences of the Thy- mutation to CHO cells.
Topics: Adenine Phosphoribosyltransferase; Alkylating Agents; Animals; Carbon-Nitrogen Ligases; Cell Line; Cricetinae; Cytarabine; Cytidine Triphosphate; Deoxycytosine Nucleotides; Deoxyribonucleotides; DNA; Drug Resistance; Female; Fluorouracil; Genes; Hypoxanthine Phosphoribosyltransferase; Ligases; Mutation; Ovary; Phenotype; Thymidine; Thymine Nucleotides; Ultraviolet Rays | 1985 |
Down syndrome and acute myeloid leukemia. Lessons learned from experience with high-dose Ara-C containing regimens.
Topics: Antineoplastic Combined Chemotherapy Protocols; Child; Cytarabine; Deoxycytosine Nucleotides; Disease-Free Survival; Dose-Response Relationship, Drug; Down Syndrome; Humans; Leukemia, Myeloid, Acute | 1999 |
41 other study(ies) available for cytarabine and 2'-deoxycytidine 5'-triphosphate
| Article | Year |
|---|---|
Compartmentation of dCTP pools disappears after hydroxyurea or araC treatment in lymphocytes.
Topics: Cytarabine; Deoxycytidine; Deoxycytosine Nucleotides; DNA; G1 Phase; Humans; Hydroxyurea; Lymphocytes; Palatine Tonsil; Phospholipids; S Phase; Thymidine | 1992 |
Increase in Ara-C sensitivity in Ara-C sensitive and -resistant leukemia by stimulation of the salvage and inhibition of the de novo pathway.
Topics: Cell Division; Cytarabine; Deoxycytidine Kinase; Deoxycytosine Nucleotides; DNA; Drug Resistance; Humans; Hydroxyurea; Leukemia, Myeloid; Tumor Cells, Cultured | 1992 |
Enhancement of the toxicity and DNA incorporation of arabinosyl-5-azacytosine and 1-beta-D-arabinofuranosylcytosine by cyclopentenyl cytosine.
Topics: Antimetabolites, Antineoplastic; Azacitidine; Cell Survival; Colorectal Neoplasms; Cytarabine; Cytidine Triphosphate; Deoxycytosine Nucleotides; DNA, Neoplasm; Humans; In Vitro Techniques; Tumor Cells, Cultured | 1990 |
Sequence-dependent interaction of 5-fluorouracil and arabinosyl-5-azacytosine or 1-beta-D-arabinofuranosylcytosine.
Topics: Antineoplastic Combined Chemotherapy Protocols; Azacitidine; Cell Division; Cell Line; Cell Nucleus; Cell Survival; Colonic Neoplasms; Cytarabine; Cytidine; Deoxycytosine Nucleotides; DNA, Neoplasm; Drug Administration Schedule; Drug Interactions; Fluorouracil; Humans; Nucleic Acids; Thymine Nucleotides; Tumor Stem Cell Assay | 1991 |
Action of 2',2'-difluorodeoxycytidine on DNA synthesis.
Topics: Antimetabolites, Antineoplastic; Base Sequence; Cells, Cultured; Cytarabine; Deoxycytidine; Deoxycytidine Monophosphate; Deoxycytosine Nucleotides; DNA; Gemcitabine; Humans; Molecular Sequence Data; RNA | 1991 |
Intracellular dCTP/ara-CTP ratio and the cytotoxic effect of ara-C.
Topics: Arabinofuranosylcytosine Triphosphate; Cell Division; Chromatography, High Pressure Liquid; Culture Media; Cytarabine; Deoxycytosine Nucleotides; DNA, Neoplasm; Humans; Tumor Cells, Cultured | 1991 |
Differential effect of interleukin 3 on the metabolism of high-dose cytosine arabinoside in normal versus leukemic human bone marrow cells.
Topics: Bone Marrow; Cytarabine; Deoxycytosine Nucleotides; DNA; Humans; Interleukin-3; Leukemia, Myeloid, Acute; Recombinant Proteins | 1991 |
Enhancement of anti-neoplastic activity of cytosine arabinoside against human HL-60 myeloid leukemic cells by 3-deazauridine.
Topics: 3-Deazauridine; Cell Line; Cell Survival; Cytarabine; Deoxycytidine Kinase; Deoxycytosine Nucleotides; Dose-Response Relationship, Drug; Drug Screening Assays, Antitumor; Drug Synergism; Humans; Leukemia, Promyelocytic, Acute | 1991 |
Effect of tetrahydrouridine and deoxytetrahydrouridine on the interaction between 2'-deoxycytidine and 1-beta-D-arabinofuranosylcytosine in human leukemia cells.
Topics: Arabinofuranosylcytosine Triphosphate; Cell Division; Cytarabine; Cytidine Deaminase; DCMP Deaminase; Deamination; Deoxycytidine; Deoxycytosine Nucleotides; DNA, Neoplasm; Humans; Leukemia; Tetrahydrouridine; Tumor Cells, Cultured | 1991 |
Concordant changes of pyrimidine metabolism in blasts of two cases of acute myeloid leukemia after repeated treatment with ara-C in vivo.
Topics: Adolescent; Adult; Arabinofuranosylcytosine Triphosphate; Cytarabine; DCMP Deaminase; Deoxycytidine Kinase; Deoxycytosine Nucleotides; Drug Resistance; Female; Humans; Leukemia, Myeloid, Acute; Male; Pyrimidines; Thymine Nucleotides | 1990 |
Differential modulation of 1-beta-D-arabinofuranosylcytosine metabolism by hydroxyurea in human leukemic cell lines.
Topics: Arabinofuranosylcytosine Triphosphate; Arabinonucleotides; B-Lymphocytes; Cell Line; Cytarabine; Deoxyadenine Nucleotides; Deoxyadenosines; Deoxycytidine; Deoxycytosine Nucleotides; Humans; Hydroxyurea; Leukemia; T-Lymphocytes; Thymine Nucleotides; Vidarabine Phosphate | 1988 |
Ara-CTP metabolism following hydroxyurea or methotrexate treatment in human leukemia cell lines.
Topics: Arabinofuranosylcytosine Triphosphate; Arabinonucleotides; Cytarabine; Deoxycytidine; Deoxycytosine Nucleotides; Drug Synergism; Humans; Hydroxyurea; Leukemia; Leukemia, Promyelocytic, Acute; Methotrexate; Thymine Nucleotides; Tumor Cells, Cultured | 1989 |
Relationship between intracellular dCTP/ara-CTP ratio and cytotoxic effect of ara-C.
Topics: Animals; Arabinofuranosylcytosine Triphosphate; Arabinonucleotides; Cytarabine; Deoxycytosine Nucleotides; Dose-Response Relationship, Drug; Humans; Leukemia, Myeloid; Leukemia, T-Cell; Mice; Spleen; Time Factors; Tumor Cells, Cultured | 1989 |
Modulation of deoxynucleotide metabolism by the deoxycytidylate deaminase inhibitor 3,4,5,6-tetrahydrodeoxyuridine.
Topics: Cell Line; Cytarabine; Cytidine Diphosphate; DCMP Deaminase; Deoxycytidine; Deoxycytidine Kinase; Deoxycytosine Nucleotides; Deoxyuridine; Hydroxyurea; Kinetics; Nucleotide Deaminases; Ribonucleotide Reductases; T-Lymphocytes; Tetrahydrouridine; Thymine Nucleotides | 1989 |
A study of the mechanisms of cytotoxicity of Ara-C on three human leukemic cell lines.
Topics: Arabinofuranosylcytosine Triphosphate; Cytarabine; Deoxycytidine Kinase; Deoxycytosine Nucleotides; DNA; DNA Ligases; DNA Polymerase II; DNA, Neoplasm; Humans; Leukemia; Leukemia, Myelogenous, Chronic, BCR-ABL Positive; Leukemia, Promyelocytic, Acute; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Tumor Cells, Cultured; Tumor Stem Cell Assay | 1989 |
Pyrimidine salvage enzymes in human tonsil lymphocytes: II. Purification and properties of deoxycytidine kinase.
Topics: Cell-Free System; Chromatography; Cytarabine; Deoxycytidine Kinase; Deoxycytosine Nucleotides; Humans; Kinetics; Lymphocytes; Molecular Weight; Palatine Tonsil; Phosphotransferases | 1985 |
Effect of recombinant GM-CSF on the metabolism of cytosine arabinoside in normal and leukemic human bone marrow cells.
Topics: Bone Marrow; Cell Division; Colony-Stimulating Factors; Cytarabine; Deoxycytosine Nucleotides; Drug Synergism; Granulocytes; Hematopoietic Stem Cells; Humans; Leukemia, Myeloid, Acute; Macrophages; Neoplastic Stem Cells; Recombinant Proteins | 1988 |
Bromodeoxyuridine enhancement of 1-beta-D-arabinofuranosylcytosine metabolic activation and toxicity in HL-60 leukemic cells.
Topics: Arabinofuranosylcytosine Triphosphate; Biotransformation; Bromodeoxyuridine; Cell Cycle; Cell Survival; Cytarabine; Deoxycytosine Nucleotides; Deoxyguanine Nucleotides; DNA, Neoplasm; Humans; Phosphorylation; Tumor Cells, Cultured | 1988 |
Effects of 1-beta-D-arabinofuranosylcytosine incorporation on elongation of specific DNA sequences by DNA polymerase beta.
Topics: Arabinofuranosylcytosine Triphosphate; Base Sequence; Cytarabine; Deoxycytosine Nucleotides; DNA; DNA Polymerase I | 1988 |
Regulation of 1-beta-D-arabinofuranosylcytosine 5'-triphosphate accumulation in human leukemia cells by deoxycytidine 5'-triphosphate.
Topics: Arabinofuranosylcytosine Triphosphate; Arabinonucleotides; Cell Cycle; Cell Line; Cytarabine; Deoxycytosine Nucleotides; Humans; Interphase; Leukemia; Nucleotides; Phosphorylation; T-Lymphocytes | 1986 |
Multipotent mutator strain of mouse teratocarcinoma cells.
Topics: Animals; Cell Line; Chimera; Cytarabine; Deoxycytosine Nucleotides; Drug Resistance; Embryonal Carcinoma Stem Cells; Mice; Mutation; Neoplasm Transplantation; Neoplastic Stem Cells; Ouabain; Phenotype; Teratoma; Thioguanine; Transplantation, Isogeneic | 1985 |
Nucleoside transport and cytosine arabinoside (araC) metabolism in human T lymphoblasts resistant to araC, thymidine and 6-methylmercaptopurine riboside.
Topics: Adenosine Kinase; Biological Transport; Cell Line; Cells, Cultured; Cytarabine; Deoxycytidine Kinase; Deoxycytosine Nucleotides; Drug Resistance; Humans; Methylthioinosine; Nucleosides; T-Lymphocytes; Thymidine; Thymidine Kinase | 1985 |
Elevation of dCTP pools in xeroderma pigmentosum variant human fibroblasts alters the effects of DNA repair arrest by arabinofuranosyl cytosine.
Topics: Cells, Cultured; Cytarabine; Deoxycytosine Nucleotides; DNA Repair; Fibroblasts; Humans; Xeroderma Pigmentosum | 1985 |
Analysis of the drug synergism between thymidine and arabinosyl cytosine using mouse S49 T lymphoma mutants.
Topics: Animals; Cells, Cultured; Cytarabine; Deoxycytosine Nucleotides; Drug Synergism; Lymphoma; Mice; Mutation; Thymidine; Thymine Nucleotides | 1985 |
Potential for selective enhancement of the in vivo metabolism of 1-beta-D-arabinofuranosylcytosine in rats by thymidine pretreatment.
Topics: Animals; Biotransformation; Colonic Neoplasms; Cytarabine; Deoxycytosine Nucleotides; Drug Therapy, Combination; Female; Rats; Rats, Inbred F344; Thymidine; Thymine Nucleotides | 1985 |
Modulation of 1-beta-D-arabinofuranosylcytosine metabolism by thymidine in human acute leukemia.
Topics: Acute Disease; Cytarabine; Deoxycytosine Nucleotides; DNA; Drug Interactions; Drug Therapy, Combination; Humans; Leukemia; Thymidine; Thymine Nucleotides | 1985 |
Enhanced production of intracellular ara-CTP after sequential use of methotrexate and 1-beta-D-arabinofuranosylcytosine.
Topics: Animals; Antineoplastic Combined Chemotherapy Protocols; Arabinofuranosylcytosine Triphosphate; Arabinonucleotides; Cytarabine; Deoxycytosine Nucleotides; Drug Administration Schedule; Leukemia L1210; Male; Methotrexate; Mice; Mice, Inbred Strains | 1985 |
Continuous infusion high-dose cytosine arabinoside in refractory childhood leukemia.
Topics: Acute Disease; Adolescent; Arabinofuranosylcytosine Triphosphate; Bone Marrow; Child; Child, Preschool; Cytarabine; Deoxycytosine Nucleotides; Drug Administration Schedule; Humans; Infusions, Parenteral; Kinetics; Leukemia; Leukemia, Lymphoid | 1984 |
Two simple high-performance liquid chromatographic methods for simultaneous determination of 2'-deoxycytidine 5'-triphosphate and cytosine arabinoside 5'-triphosphate concentrations in biological samples.
Topics: Arabinofuranosylcytosine Triphosphate; Arabinonucleotides; Bone Marrow; Child; Chromatography, High Pressure Liquid; Cytarabine; Deoxycytosine Nucleotides; Humans; Leukemia; Spectrophotometry, Ultraviolet | 1982 |
Molecular effects of 2',2'-difluorodeoxycytidine (Gemcitabine) on DNA replication in intact HL-60 cells.
Topics: Antimetabolites, Antineoplastic; Cell Death; Cytarabine; Deoxycytidine; Deoxycytosine Nucleotides; Deoxyguanine Nucleotides; DNA Replication; DNA, Neoplasm; Dose-Response Relationship, Drug; Drug Stability; Gemcitabine; Humans; Hydrogen-Ion Concentration; Tumor Cells, Cultured | 1994 |
Effect of granulocyte-macrophage colony-stimulating factor on the metabolism of arabinosylcytosine triphosphate in blasts during therapy of patients with chronic myelogenous leukemia.
Topics: Arabinofuranosylcytosine Triphosphate; Blast Crisis; Cytarabine; Deoxycytosine Nucleotides; Drug Therapy, Combination; Granulocyte-Macrophage Colony-Stimulating Factor; Humans; Leukemia, Myelogenous, Chronic, BCR-ABL Positive; Tumor Cells, Cultured | 1994 |
Recombinant GM-CSF modulates the metabolism of cytosine arabinoside in leukemic cells in bone marrow.
Topics: Arabinofuranosylcytosine Triphosphate; Bone Marrow; Bone Marrow Cells; Cytarabine; Deoxycytosine Nucleotides; DNA, Neoplasm; Granulocyte-Macrophage Colony-Stimulating Factor; Humans; Intracellular Fluid; Kinetics; Leukemia, Myeloid, Acute; Leukocytes, Mononuclear; Recombinant Proteins; S Phase; Tritium; Tumor Cells, Cultured | 1993 |
Enhanced metabolism of 1-beta-D-arabinofuranosylcytosine in Down syndrome cells: a contributing factor to the superior event free survival of Down syndrome children with acute myeloid leukemia.
Topics: Acute Disease; Adolescent; Antineoplastic Combined Chemotherapy Protocols; Arabinofuranosylcytosine Triphosphate; Cell Line, Transformed; Cells, Cultured; Child; Child, Preschool; Chromosomes, Human, Pair 21; Cystathionine beta-Synthase; Cytarabine; Deoxycytosine Nucleotides; Disease-Free Survival; Down Syndrome; Female; Herpesvirus 4, Human; Homocysteine; Humans; Infant; Infant, Newborn; Leukemia, Megakaryoblastic, Acute; Leukemia, Myeloid; Male; Methotrexate; Myelodysplastic Syndromes; Neoplastic Stem Cells; Remission, Spontaneous; Survival Rate | 1996 |
Deoxycytidine in human plasma: potential for protecting leukemic cells during chemotherapy.
Topics: Adult; Cladribine; Cytarabine; Deoxycytidine; Deoxycytosine Nucleotides; Humans; Male; Middle Aged; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Vidarabine | 1997 |
Regulation of deoxycytidine kinase by deoxycytidine and deoxycytidine 5' triphosphate in whole leukemia and tumor cells.
Topics: Animals; Arabinofuranosylcytosine Triphosphate; CHO Cells; Cricetinae; Cytarabine; Deoxycytidine; Deoxycytidine Kinase; Deoxycytosine Nucleotides; HL-60 Cells; Homeostasis; Humans; Leukemia; Ribonucleotide Reductases; Tumor Cells, Cultured | 1998 |
Metabolism of 4'-thio-beta-D-arabinofuranosylcytosine in CEM cells.
Topics: Animals; Antineoplastic Agents; Arabinonucleosides; Biological Transport; Cell Division; Cytarabine; Cytidine Deaminase; Deamination; Deoxycytidine; Deoxycytidine Kinase; Deoxycytosine Nucleotides; DNA; Humans; Male; Mice; Mice, Nude; Thionucleosides; Tumor Cells, Cultured | 2000 |
Cellular pharmacokinetics and pharmacodynamics of the deoxycytidine analog 2'-C-cyano-2'-deoxy-1-beta-D-arabino-pentofuranosylcytosine (CNDAC).
Topics: Antineoplastic Agents; Cell Division; Cytarabine; Deoxycytosine Nucleotides; Deoxyribonucleotides; DNA; Humans; RNA; Tumor Cells, Cultured | 2001 |
Pharmacological basis for cladribine resistance in a human acute T lymphoblastic leukaemia cell line selected for resistance to etoposide.
Topics: 5'-Nucleotidase; Blotting, Western; Cell Line; Cladribine; Cytarabine; Deoxycytidine Kinase; Deoxycytosine Nucleotides; DNA Topoisomerases, Type II; Drug Resistance, Microbial; Etoposide; Fas Ligand Protein; Genes, MDR; Humans; Isoenzymes; Leukemia-Lymphoma, Adult T-Cell; Membrane Glycoproteins | 2001 |
Cyclopentenyl cytosine increases the phosphorylation and incorporation into dna of arabinofu-ranosyl cytosine in a myeloid leukemic cell-line.
Topics: Antimetabolites, Antineoplastic; Antineoplastic Agents; Carbon-Nitrogen Ligases; Cytarabine; Cytidine; Cytidine Diphosphate; Cytidine Monophosphate; Deoxycytosine Nucleotides; DNA; Dose-Response Relationship, Drug; Enzyme Inhibitors; HL-60 Cells; Humans; Leukemia, Myeloid; Phosphorylation | 2000 |
Amidox, an inhibitor of ribonucleotide reductase, potentiates the action of Ara-C in HL-60 human promyelocytic leukemia cells.
Topics: Agar; Antimetabolites, Antineoplastic; Antineoplastic Combined Chemotherapy Protocols; Cell Line, Tumor; Cell Proliferation; Chromatography, High Pressure Liquid; Cytarabine; Deoxycytosine Nucleotides; Drug Synergism; Enzyme Inhibitors; HL-60 Cells; Humans; Inhibitory Concentration 50; Oximes; Ribonucleotide Reductases; Time Factors | 2004 |
Resistance to 9-beta-D-arabinofuranosyl-2-fluoroadenine due to reduced incorporation into DNA from competition by excess deoxyadenosine triphosphate: implications for different sensitivities to nucleoside analogues.
Topics: Animals; Binding, Competitive; Biotransformation; Cell Line, Tumor; Cell Proliferation; Cytarabine; Deoxyadenine Nucleotides; Deoxycytosine Nucleotides; DNA; Drug Interactions; Drug Resistance, Neoplasm; Hydroxyurea; Mice; Nucleosides; Vidarabine | 2005 |